Gene cam-1 (Nematode worm)

cam-1

Species: Nematode worm
Alias: cam-1, C01G6.8b, C01G6.8, CE24774, kin-8, Cehd-17, aSWK402
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: II: 9304727-9304727, WormBase Genetic Map location: II:1.0557,

Classification

Group: TK
Family: Ror

Sequence

Name Sequence Type Origin Length Description Download
cam-1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 272 Kinase domain by global Sugen HMM Fasta, JSON
cam-1.AA Protein Genbank 928 None Fasta, JSON

Protein domain

Protein domains of cam-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
I-set cam-1.AA I-set 38-127 23 7.9e-18 63.02 Pfam 1-92 (92) Show / Hide 
Range on Protein: 38-127
Range on HMM: 1-92/92
Sequence Identity: 23% (22 aa)

IRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEK-TKRVKIRDKE-NSSRLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRV
 . | ...... . |. .||.|.. |.|| .  |.|.. |.   ..|.... .. . ..| |.. .  |.| | |...|.. .. .|  | |
PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV
IGc2 cam-1.AA IGc2 50-117 27 2.3e-11 45.01 SMART 1-56 (56) Show / Hide 
Range on Protein: 50-117
Range on HMM: 1-56/56
Sequence Identity: 27% (19 aa)

SSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQLDVLDSGYYQCIVSNPAA
 .|. |...|.| | |   . |.| . |..           ....| |.   . |||||.|...||. 
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG
IG cam-1.AA IG 44-128 15 8.6e-10 39.78 SMART 1-58 (58) Show / Hide 
Range on Protein: 44-128
Range on HMM: 1-58/58
Sequence Identity: 15% (14 aa)

LRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQLDVLDS---GYYQCIVSNPAASVNT--TSVLRVN
 .  | . |. |...| .       . |.                      |.| .. . ||   | |.| ..  . ..    .  |.| 
PP-VTVKEGETVTLTC-VS-----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ
V-set cam-1.AA V-set 24-127 15 5.3e-05 19.09 Pfam 1-128 (128) Show / Hide 
Range on Protein: 24-127
Range on HMM: 1-128/128
Sequence Identity: 15% (21 aa)

NASMEG-TSTGQRPYIRLTSQLRNATKSSGDEVRFKCEAL-GT----PPLKFIWLK-NNG---------------PVEKTKRVKIRDKENSS-----R--
  .... ...|. |           |.. |. |...|    ..    ... . | .  .                ......... | |.. .     .  
QSQVTQHPPRGC-PW--------WVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKN

---LVITQLDVLDSGYYQCIVSNP-AASVNTTSVLRV
   | |..| . ||| | | |.|.   .  .   |.|
DFSLTISNLQPSDSGTYYCAVWNCNEDYFGHGTRLTV
KR cam-1.AA KR 352-431 35 1.1e-35 125.81 SMART 1-90 (90) Show / Hide 
Range on Protein: 352-431
Range on HMM: 1-90/90
Sequence Identity: 35% (32 aa)

HWCYVN--SGTQYEGTVAQTSSGKQCAPWIDSTSRDFNV--HRFPELM----NSKNYCRNPGGKKSRPWCYSKPMGQE--EYCDVPQCPS
..||..  .|..|.|||..| ||..| .| . .. . .   ..||...    .  ||||||.|.. .|||| . ....  ||||.|||..
RDCYWGDDNGESYRGTVNTTWSGHPCQRWDSQYPHLHWFYPEWFPCAGQLGLLEHNYCRNPDGDSEGPWCYTMDPNVRDWEYCDIPQCED
Kringle cam-1.AA Kringle 354-429 38 4.3e-17 61.01 Pfam 1-85 (85) Show / Hide 
Range on Protein: 354-429
Range on HMM: 1-85/85
Sequence Identity: 38% (33 aa)

CYVNSGTQYEGTVAQTSSGKQCAPW-IDSTSR-DF-NVHRFPELMNSK---NYCRNPGGKKSRPWCYS--KPMGQEEYC-DVPQC
|| . | .| ||...| ||..| .|   .. |  | . ..||         |||||| |    ||||    | .. ||| |.|.|
CYHGNGENYRGTWSTTESGRPCQRWDSQTPHRHPFYTPENFPCKGLGEGKHNYCRNPDGDERGPWCYTQTDPRVRWEYCSDIPRC
Kinase cam-1.AA Ror 590-861 57 5.2e-222 743.84 In-house 1-279 (308) Show / Hide 
Range on Protein: 590-861
Range on HMM: 1-279/308
Sequence Identity: 57% (161 aa)

LSVREKIGEGQFGVVHSGIYTSGLFAPEPMAVAVKKCRHDATNAERAQLEQEIRAVATFDHPNVIKLIGVCYMDNSLLAVFEYMVHGDLHELLKVRVPPA
....|..||.|||.|..|......|....||||.|.|.|||..|......|||...||..|||...|.|||.||......||||.||||||.|..|.|..
VRFMEELGECQFGKVYKGHLMGPNFMYHCMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMDQPYCMLFEYMNHGDLHEFLIMRSPHS

DHD-------MGGITEANAEFLYIATQIALGMEYLASMSFVHRDLATRNCLVGDTRTIKIADFGLMRTSYGSDYYKMLHRSWMPVRWMSKEAIEQGRFSE
||.       |.........||.||.|||.|||||.|..|||||||.||||||.....||.||||||..|.||||.|.|.||||.||||.|||..|.|||
DHGCSSDDDRMVKSSLDHPDFLHIAIQIAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGLMRDIYSSDYYRMQHKSWMPIRWMSPEAIMYGKFSE

ASDVWSFGVTLWEIWSFGRQPYEGASNQQVIELVANRHLLECPHNCPTNIYSLMVECWHENIERRPTFSEIRSRLQSWS
.||.|||||.||||||.|.|||.|.|||.|||...|||||.|||||||.|||||.|||||...|||.|..|.|||.||.
DSDIWSFGVVLWEIWSYGMQPYYGYSNQEVIEMIRNRHLLPCPHNCPTWIYSLMIECWHEIPSRRPRFKDIHSRLRSWD
Kinase cam-1.AA TyrKc 590-857 38 9.5e-132 444.9 SMART 1-280 (280) Show / Hide 
Range on Protein: 590-857
Range on HMM: 1-280/280
Sequence Identity: 38% (117 aa)

LSVREKIGEGQFGVVHSGIYTSGLFAPEPMAVAVKKCRHDATNAERAQLEQEIRAVATF--DHPNVIKLIGVCYMD-------NSLLAVFEYMVHGDLHE
..  .|.|||.||.|. |...        . ||||....||    |. . .|.|    .  .|||...|.|||  .         |. |.||| ||||..
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

LLKVRVPPADHDMGGITEANAEFLYIATQIALGMEYLASMSFVHRDLATRNCLVGDTRTIKIADFGLMRTSYGS-------DYYKM----LHRSWMPVRW
 |. . |            ....|....||| |||||.|. ..|||||.||||||. .|.||.||||.|  |         |||..      ....|.||
YLRKHRPK---------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW

MSKEAIEQGRFSEASDVWSFGVTLWEIWSFGRQPYEG-----ASNQQVIELVANRHLLECPHN--------CPTNIYSLMVECWHENIERRPTFSEIRSR
|. |.|  |.|...||||||||..||| ..| |||.|      |||.|||.| ... ...|.|        ||. .|..| .||||. | |||||||...
MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHEC

L
.
F
Kinase cam-1.AA Pkinase_Tyr 590-857 39 2.9e-130 441.8 Pfam 1-270 (270) Show / Hide 
Range on Protein: 590-857
Range on HMM: 1-270/270
Sequence Identity: 39% (110 aa)

LSVREKIGEGQFGVVHSGIYTSGLFAPEPMAVAVKKCRHDATNAE--RAQLEQEIRAVATF-DHPNVIKLIGVCY-MDNS--LLAVFEYMVHGDLHELLK
..  .|.|||.||.|. |...  .   . . ||||.....|.  .  |. . .|..   .. .|||...|.|||.  . .  .. |.||| ||||.. |.
ITFGKKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

VRVPPADHDMGGITEANAEFLYIATQIALGMEYLASMSFVHRDLATRNCLVGDTRTIKIADFGLMRTSYGSDYY-KMLHRSWMPVRWMSKEAIEQGRFSE
 .       ...      . | ...||| |||||.|. ..|||||.|||||......||.||||.|. |  ||| .. . . .|..||. |.|  |.|..
KHR------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTT

ASDVWSFGVTLWEIWSFGRQP-YEGASNQQVIELV-ANRHLLECPHNCPTNIYSLMVECWHENIERRPTFSEIRSRL
.||||||||..||| ..|.|| |.| ||..|.|..  ... ..||.|||  ||.|| .|||.. |.|||||||...|
KSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase cam-1.AA TK 590-857 22 7.29999999999e-110 369.61 In-house 1-486 (486) Show / Hide 
Range on Protein: 590-857
Range on HMM: 1-486/486
Sequence Identity: 22% (110 aa)

LSVREKIGEGQFG---VVHSGIYTSGLF--------------------APEPMAVAVKKCRHDATNAERAQLE-------------QEIRAVATFD----
. . .|.||||||   .|. |.. ..                        ... |||| .. ...........             .| .. . ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNVIKLIGVCYMD------------NSLLAVFEYMVHGD----LHELLKVRVPPADHDMGGITEANAEFLY---------------------------
 |||...|.|||  .              .. | ||| |||    |.. |. . |.. |   .. . ..  ..                           
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------------------------------------IATQIALGMEYLASM------SFVHRDLATRNCLVGDTRT-----------IKIADFG----
                                      .. ||| |||||.|.       |||||||.||||||.  .           .||||||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LMRTSY------------------------GSDYYKMLHRSWMPVRWMSKEAIE---------QGRFSEASDVWSFGVTLWEIWSFGRQPYEG-AS
    | |  |                        ..|||.. .. ..|.|||. |...          |.|...||||||||..|||...|..|| |  |
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

N---------QQVIELVAN--------------RHLLECPHNCP--------------TNIYSLMVECWHENIERRPTFSEIRSRL
|         |.|.|.. .              |. ...| .||              . .| || .|||.. |.|||||.....|
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase cam-1.AA UTK 590-857 37 1.1e-97 330.82 In-house 1-296 (296) Show / Hide 
Range on Protein: 590-857
Range on HMM: 1-296/296
Sequence Identity: 37% (113 aa)

LSVREKIGEGQFGVVHSGIYTSGLFAPEPMAVAVKKCR-HDATNAERA---QLEQEIR---AVATFD-HPNVIKLIGVCYMDNSLLAVFEYMVHGDLHEL
.  ....|.|.||.|| . .|      . |.||||.|. |.... |..   ..  | |     . |. ||||..|.|||  .  .. | |||. |||  .
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LKVRVPPADHDMGGITEANAEFLY------IATQIALGMEYLASMSFVHRDLATRNCLVGDTR-------TIKIADFG---LMRTSY---------GSDY
|    | ..        |. ..|        | .|| ||.||.|. ||||||| |||||.. |       ..||||||   . |  .         .|.|
LRRHRPTPP--------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYY

YKMLHRSWMPVRWMSKEAIEQG-RFSEASDVWSFGVTLWEIWSFGRQPYEGASNQQVIELVANR--HLLECPHNCPTNIYSLMVECWHENIERRPTFSEI
|.. |.  .|.|||. ||. .. ||...||||||||..||||..||.||.| ||.||.. | |.  ....||. || ..| ||..||| ....||.| ..
YMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDL

RSRL
....
VQQM
Kinase cam-1.AA Trk 590-857 38 1.6e-92 313.71 In-house 1-275 (275) Show / Hide 
Range on Protein: 590-857
Range on HMM: 1-275/275
Sequence Identity: 38% (105 aa)

LSVREKIGEGQFGVVHSGIYTSGLFAPEPMAVAVKKCRHDATNAERAQLEQEIRAVATFDHPNVIKLIGVCYMDNSLLAVFEYMVHGDLHELLKVRVPPA
.  .  .||| ||.|  .     . . ..| ||||  . ||... |   . | .     .|....|. |||  .. || ||||| |||| . |. . | |
IVLKWELGEGAFGKVFLAECYNLCPEQDKMMVAVKTLK-DASENARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPDA

DHDMGGIT------EANAEFLYIATQIALGMEYLASMSFVHRDLATRNCLVGDTRTIKIADFGLMRTSYG-SDYYKMLHRSWMPVRWMSKEAIEQGRFSE
.  ...            . |.|| ||| || |.|| .|||||.||||||||.   .||.|||. |  |  .|||.. |.  .|.|||  |.|   .|. 
MCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESIMYRKFTY

ASDVWSFGVTLWEIWSFGRQPYEGASNQQVIELVANRHL-LECPHNCPTNIYSLMVECWHENIERRPTFSEIRSRL
 ||||||||..||. ..|.||. . ||. ||| . .  . ||.|  || ..| .|. ||.   ..| .  .|  ..
ESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase cam-1.AA DDR 590-857 39 5.1e-91 308.7 In-house 1-306 (306) Show / Hide 
Range on Protein: 590-857
Range on HMM: 1-306/306
Sequence Identity: 39% (122 aa)

LSVREKIGEGQFGVVHSGIYTSGL------FAPE-----PMAVAVKKCRHDATNAERAQLEQEIRAVATFD-HPNVIKLIGVCYMDNSLLAVFEYMVH-G
| . ||||||||| ||  .  ...      |. .     |. ||||. | ||. . |. . .||.  .    |||...|.|||  | ... . |||   |
LIFVEKIGEGQFGEVHLCEVEGMQDYIEFDFHCDVHKGHPTLVAVKMLRPDACKHARNDFHKEIKCMSQCKRHPNIVRLVGVCTQDEPYCMIMEYMENLG

DLHELLKVRVPP--ADHDMG-------GITEANAEFLYIATQIALGMEYLASMSFVHRDLATRNCLVGDTRTIKIADFG--LMRTSYGSDYYKMLH----
||   .  ....  .  ..        . |   .  .||.|||| || ||.|| ||||||||||||||   .|||.|||  . |  | .|||.       
DLNQFWMEHEAENSGLMNCKADTQNCQKPTISYECCVYICTQIASGMKYLESMNFVHRDLATRNCLVGKEYHIKICDFGTVMSRNLYSQDYYRVEGFTGR

-RSWMPVRWMSKEAIEQGRFSEASDVWSFGVTLWEIWSFGR-QPYEGASNQQVIE-------LVANRHLLECPHNCPTNIY-SLMVECWHENIERRPTFS
 |  ||.|||. |.|  | |. .||||.||||.||. .| | ||||  .. ||||          .  .|  | .||  ||  || .||    ..||.|.
QRHHMPIRWMAWESILLGKFTTKSDVWAFGVTMWEMFMFCREQPYEQLTDEQVIENACEFFRHQGMQVYLPMPPMCPYEIYNQLMCRCWRRDQSQRPSFE

EIRSRL
||   |
EIHKFL
Kinase cam-1.AA CTKA 590-857 39 4.6e-88 296.01 In-house 1-290 (290) Show / Hide 
Range on Protein: 590-857
Range on HMM: 1-290/290
Sequence Identity: 39% (116 aa)

LSVREKIGEGQFGVVHSGIYTSGLFAPEPM----------AVAVKKCRHDATNAERAQLEQEIRAVA--TFDHPNVIKLIGVCYMDNSLLAVFEYMVHGD
. .  |||||..| |   .       |.|            ||||  . .|| ..|     | .  .   |.||||. |.|||  .  .. . |.|  ||
HCIMFKIGEGHYGQVFRAW-----LMPDPDDFKAQRKKGKDVAVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGD

LHELLKVRVPPAD-------------HDMGGITEANAEFLYIATQIALGMEYLASMSFVHRDLATRNCLVGDTRTIKIADFGLMRTSYGS-DYYKMLHRS
||  |. .  |||                  |     |  | | ||| ||.|||.| ||||||| ||||.|   .|||||||. ||  .   || .  ..
LHCYLR-ACRPADGQVCPARARRSIPRSFHPIEVHAHEQVYMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQR

WMPVRWMSKEAIEQGRFSEASDVWSFGVTLWEIWSFGRQPYEGASNQQVIELVANR--HLLECPHNCPTNIYSLMVECWHENIERRPTFSEIRSRL
 ||||||. ||.  |.|| |||||.||| |||| |.|  |. . | | | ....      |  | |||  .|..| |||      ||||  ..  |
VMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHMSDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase cam-1.AA Musk 592-857 40 1.4e-84 279.38 In-house 4-282 (282) Show / Hide 
Range on Protein: 592-857
Range on HMM: 4-282/282
Sequence Identity: 40% (115 aa)

VREKIGEGQFGVVHSGIYTSGLFAPEP-MAVAVKKCRHDATNAERAQLEQEIRAVATFDHPNVIKLIGVCYMDNSLLAVFEYMVHGDLHELLKVRVPPAD
||. |||| || |       || . |. . ||||  . || .   .  . |   .| |||||..|| ||| .   .   ||||  ||| | |. . | . 
VRD-IGEGAFGRVFQ-ARAPGLVPYEEETMVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDLNEFLHSCSPHRT

HDMGGITEA--------------NAEFLYIATQIALGMEYLASMSFVHRDLATRNCLVGDTRTIKIADFGLMRTSYGSDYYKMLHRSWMPVRWMSKEAIE
.       .               .. | .| ||| || ||  | ||||||||||||....  .||||||| |  |  ||||       |.|||  |.| 
CSRTHQDRGMRAQVSSPGPPQLKCYHQLCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPESIW

QGRFSEASDVWSFGVTLWEIWSFGRQPYEGASNQQVIELVANRHLLECPHNCPTNIYSLMVECWHENIERRPTFSEIRSRL
  .|. .||||..|| |||| |.. ||| | .   ||  . .   | || ||| ..| || .||  |   || | .|   .
YNQFTYESDVWAYGVCLWEIFSYALQPYYGMTHEEVIYYIRQGNILSCPENCPQKVYQLMRRCWQKNPADRPFFCQIHHCI
Kinase cam-1.AA TK-Unique 590-857 32 3.9e-83 282.51 In-house 1-294 (294) Show / Hide 
Range on Protein: 590-857
Range on HMM: 1-294/294
Sequence Identity: 32% (96 aa)

LSVREKIGEGQFGVVHSGIYTSGL-FAPEPMAVAVKKCRHDATNAERAQLEQEIRAVATFD-HPNVIKLIGVCYMD-NSLLAVFEYMVHGDLHELLKVRV
| | ..||||.|| |. | ....     ..  ||||... .||  ..... .||.     . |||.....|.|  . .. . ..||.  |.|  .|. . 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

PP--------------ADHDMGGITE-ANAEFLY-IATQIALGMEYLAS--MSFVHRDLATRNCLVGDTRTIKIADFGLMR-TSYGSDYYKMLHRSWMPV
|.              . . ..  ||  . ..|| .| ||| |||||||  . .|||||..||.|...  ..||.|||. | .. . .| .|  .. .|.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWMSKEAIE--QGRF-SEASDVWSFGVTLWEIWSFGRQPYEGASNQQVIELVANRHLLECPHNC-PTNIYSLMVECWHENIERRPTFSEIRSRL
|||..|..   .| . .. ||||||||..||| ..| .|| | .. ...|.. . . .. | .| .  .|.|| .||... | ||.|..|..||
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase cam-1.AA Src 590-857 37 9.1e-81 274.13 In-house 1-255 (255) Show / Hide 
Range on Protein: 590-857
Range on HMM: 1-255/255
Sequence Identity: 37% (101 aa)

LSVREKIGEGQFGVVHSGIYTSGLFAPEPMAVAVKKCRHDATNAERAQLEQEIRAVATFDHPNVIKLIGVCYMDNSLLAVFEYMVHGDLHELLKVRVPPA
.   .|.|.|||| |  |..         . ||||  . .    . ... ||. .  ...|.....|  ||  .   . | ||| || | . ||      
IKLCRKLGQGQFGEVWMGYWN------GNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK-----

DHDMGGITEANAEFLYIATQIALGMEYLASMSFVHRDLATRNCLVGDTRTIKIADFGLMRTSY-GSDYYKMLHRSWMPVRWMSKEAIEQGRFSEASDVWS
  |  | .    . ...|.|.| ||.|| || ..||||| || |||..   |.||||| |    . | | . | . .|..|.  |||  |||.  |||||
--DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWS

FGVTLWEIWSFGRQPYEGASNQQVIELVANRHLLECPHNCPTNIYS-LMVECWHENIERRPTFSEIRSRL
||. |.|| ..|| ||.| .|..|.. | .   . |||||| ..|  .| .|||.  |.||||  ... |
FGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase cam-1.AA InsR 590-859 36 2.2e-80 269.7 In-house 1-278 (278) Show / Hide 
Range on Protein: 590-859
Range on HMM: 1-278/278
Sequence Identity: 36% (102 aa)

LSVREKIGEGQFGVVHSGIYTSGLFAPEPM--AVAVKKCRHDATNAERAQLEQEIRAVATFDHPNVIKLIGVCYMDNSLLAVFEYMVHGDLHELLKVRVP
.    . |.| || |  ||  . .   |    ..|.|    .|.  ||    .|      |.. .|..| |||      ..| | | .|||   |  | |
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP

PAD-HDMGGI----TEANAEFLYIATQIALGMEYLASMSFVHRDLATRNCLVGDTRTIKIADFGLMRTSYGSDYYKMLHRSWMPVRWMSKEAIEQGRFSE
 .   ..| .      .  ...  | .|. || |||.  ||||||| |||.| .  |.||.|||. |  | .|||.   .. .|||||. | .  | |. 
EEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKDGVFTT

ASDVWSFGVTLWEIWSFGRQPYEGASNQQVIELV-ANRHLLECPHNCPTNIYSLMVECWHENIERRPTFSEIRSRLQS
.|||||||| |||. ..| ||| | || || . .  .. .|. | |||   . ||  ||. .   |||| .| . |. 
HSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase cam-1.AA S_TKc 590-861 23 9.6e-36 125.99 SMART 1-231 (231) Show / Hide 
Range on Protein: 590-861
Range on HMM: 1-231/231
Sequence Identity: 23% (66 aa)

LSVREKIGEGQFGVVHSGIYTSGLFAPEPMAVAVKKCRHDATNAERAQLEQEIRAVATFDHPNVIKLIGVCYMDNSLLAVFEYMVH--GDLHELLKVRVP
  . .|||.| ||.|. .. ..         ||.|. .         ....||.     .|||..||..|..  ..|  |.||. .  |||....| | .
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

PADHDMGGITEANAEFLYIATQIALGMEYLASMSFVHRDLATRNCLVGDTRTIKIADFGLMRTSYGSDYYKMLHRSWMPVRWMSKEAIEQGRFSE-ASDV
.  .   ...|  |   ... ||....||. |. ..||||   | |. .  .|||.|||| |           .       .|. | .    ..  ..|.
HGLR--FPFPE-HA--RFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDW

WSFGVTLWEIWSFGRQPYEGASNQQVIELVANRHLLECPHNCPTNIYSLMVECWHENIERRPTFSEIRS-----RLQSWS
||.|..|.|  . |. |..    |......            .    ...  |.. . |.|||  |.       ..  | 
WSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase cam-1.AA Pkinase 590-747 27 3.5e-24 86.57 Pfam 1-158 (293) Show / Hide 
Range on Protein: 590-747
Range on HMM: 1-158/293
Sequence Identity: 27% (47 aa)

LSVREKIGEGQFGVVHSGIYTSGLFAPEPMAVAVKKCRHDATNAERAQLEQ---EIRAVATFDHPNVIKLIGVCYMDNSLLAVFEYMVHG----DLHELL
. . .|||.| ||.|       .    ..  ||||. . . .. .  |      ||.  . ..|||...|..... ....  |.||. .|    ||....
YHIGRKIGSGSFGCV-----YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

KVRVPPADHDMGGI--TEANAEFLYIATQIALGMEYLASMSFVHRDLATRNCLVGDTRTI----KIADFGL
..      .. |..  .|   |   ...||. |.||. ||...||||   |.|. .. .|    ||.||||
ST------WRHGCFYFSE--WECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGL
Kinase cam-1.AA Pkinase 768-857 15 5.1e-08 29.45 Pfam 176-293 (293) Show / Hide 
Range on Protein: 768-857
Range on HMM: 176-293/293
Sequence Identity: 15% (19 aa)

RWMSKEAIE-QGRFSEASDVWSFGVTLWEIWSFGRQPYEGA----SNQQVIELVANRHLLECPHNCP-----------------------TNIYSLMVEC
..|. | |  .   . ..|.||.|..|.|  . || |. |.    .    .......   . . ..|                        .  ...  |
WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC

WHENIERRPTFSEIRSR--L
.. . ..|||. .|     .
LCKDPKKRPTAEQILQHPWF