Gene F01D4.3 (Nematode worm)

F01D4.3

Species: Nematode worm
Alias: aSWK360, F01D4.3, CE09155
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: IV: 10475020-10473617, WormBase Genetic Map location: IV:4.66,

Classification

Group: TK
Family: Fer

Sequence

Name Sequence Type Origin Length Description Download
F01D4.3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 251 Kinase domain by global Sugen HMM Fasta, JSON
F01D4.3.AA Protein Genbank 399 None Fasta, JSON

Protein domain

Protein domains of F01D4.3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 F01D4.3.AA SH2 6-82 26 1.9e-16 61.92 SMART 1-87 (87) Show / Hide 
Range on Protein: 6-82
Range on HMM: 1-87/87
Sequence Identity: 26% (23 aa)

FNFYHGFLPREDLHSTLHNS----GDYLIRVSEVVEGET----KVNRECRNVVIKRVG-NKCFCEP--TRTFESVTDLIKYYTDNSGS
 ..|||...||. .. | |     ||.|.| ||   |.     ........ .|.| . .| ...    |.|.|. .|. .|. |...
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 F01D4.3.AA SH2 8-76 22 5.4e-07 22.35 Pfam 1-81 (81) Show / Hide 
Range on Protein: 8-76
Range on HMM: 1-81/81
Sequence Identity: 22% (19 aa)

FYHGFLPREDLHSTLHN----SGDYLIRVSE---------VVEGETKVNRECRNVVIKRVGNK-CFCEPTRTFESVTDLIKYY
.|||...|.. .  | |     |..|.| ||         |. . .  . . .  .|.| .|.  ..   ..|.|. .|. .|
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGP--GDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
Kinase F01D4.3.AA Fer 106-364 43 1.7e-142 479.72 In-house 1-283 (283) Show / Hide 
Range on Protein: 106-364
Range on HMM: 1-283/283
Sequence Identity: 43% (124 aa)

VTAGKVLGEGAFGKVFSG--TLKLKDGSSAEV---AIKMTKV-SAFLSKIKIKEMMNEARFIRN-FNHKNVVRLYGVAHDEQPLYILLELVKGGSLQDHM
|| ||.|||||||.|..|  |||.|.| ...|   |.|..|. .....| .|||.|.|||..|| ..|.|||..|||..||||..|..|...||||....
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

KKAKATGTVVPIAEKVRFCIGAARGIEYLHQNNCIHRDIAARNCLLSE-KEVK---ITDFGLSRN----GPSYKIK-AACKLPVKWLAPETLSSLCFTFA
|| |.   .|...||.|.|..||.|.||||..|||||||||||||... | .|   |.|||.||.    |..|| | .|||.|..||||||... .....
KKNKNK--TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPK

TDVYSWGITCYEVFADGAEPYEG----IPNATV-----KADVLNNKFIQMPPHCPDSIKKYMSTFIFV-DASCRASMTMAIGDFE
|||.|.|..|.|.|..|||||.|    . ...|     |... .... .||.|.|. |...| . ... | ..|..|. ..  ..
TDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase F01D4.3.AA TyrKc 106-363 34 1.7e-112 380.98 SMART 1-280 (280) Show / Hide 
Range on Protein: 106-363
Range on HMM: 1-280/280
Sequence Identity: 34% (101 aa)

VTAGKVLGEGAFGKVFSGTLKLKDGSSAEVAIKMTKVSAFLSKIKIKEMMNEARFIRNF--NHKNVVRLYGVAHDE-------QPLYILLELVKGGSLQD
.| ||.|||||||.|. ||.|       .||.|| | .|      ....|.|||  ...  .|.|.||||||. ..       .||.|..|....|.|.|
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

HMKKAKATGTVVPIAEKVRFCIGAARGIEYLHQNNCIHRDIAARNCLLSEKE-VKITDFGLSRNGPSY-------KIKAA-----CK--LPVKWLAPETL
. .| . .   .. .... ||. .|.| ||||..||||||.||||||..|.  |||.||||||.. ..       . . .     .|  ||..|.|||..
YLRKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

SSLCFTFATDVYSWGITCYEVFADGAEPYEG-----IPNATVKADVLNNKFIQMPPH--------CPDSIKKYMSTFIFVDASCRASMTMAIGDF
   .||...||.|.|....|.| .|..||.|     ..|. | ..| . .    ||.        ||| . . |..    |...| ...  . .|
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase F01D4.3.AA Pkinase_Tyr 106-342 37 1.2e-86 294.11 Pfam 1-249 (270) Show / Hide 
Range on Protein: 106-342
Range on HMM: 1-249/270
Sequence Identity: 37% (94 aa)

VTAGKVLGEGAFGKVFSGTLK-LKDGSSAEVAIKMTKVSAFLSKIK--IKEMMNEARFIRNF-NHKNVVRLYGVAH-DEQP--LYILLELVKGGSLQDHM
.| ||.|||||||.|. ||.| ..|.   .||.|| |     ..    ....|.||.  ... .|.|.||||||   ...|  .|| .|....|.| |. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK--EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KKAKATGTVVPIAEKVRFCIGAARGIEYLHQNNCIHRDIAARNCLLS-EKEVKITDFGLSRNG---PSY-KIKAACKLPVKWLAPETLSSLCFTFATDVY
.| .  .  ... ... .|.  |.| |||...||||||.||||||.. .. |||.||||.|       | . .  .|||.||.||| ..   || ..||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SWGITCYEVFADGAEP-YEGIPNATVKADV-LNNKFIQMPPHCPDSIKKYM
| |....|.|  |..| |.|..|. |.. .  ..    .|..||| | . |
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLM
Kinase F01D4.3.AA TK 106-363 19 8.8e-83 277.22 In-house 1-486 (486) Show / Hide 
Range on Protein: 106-363
Range on HMM: 1-486/486
Sequence Identity: 19% (96 aa)

VTAGKVLGEGAFG---KVFSGTLKLKDGSSA----------------------EVAIKMTKV-SAFLSKIKIKEMMN----------EARFIRNFN----
.| ||.||||.||   .|. |... .... .                      .||.|| |  .|  .. .. |.|.          ||. .  ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HKNVVRLYGVAHDE------------QPLYILLELVKGGS----LQDHMKKAKATGTV-----------------------------------------
 |.|.|||||| ...            .|..|..|....|.    |.|. .| . ...                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------VPIAEKVRFCIGAARGIEYLHQN------NCIHRDIAARNCLLSEKE------------VKITDFGLSR
                               .. .... .|  .|.| ||||..      |..|||.||||||..|.             .||.||||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----------NGPSYKIKA------------------------ACKLPVKWLAPETLS---------SLCFTFATDVYSWGITCYEVFADGAEPYEG-I
           ..  |  |                          .|||..|.|||.|             || ..||.|.|....|.|  |.||| | .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

PN---------ATVKADVLN------------NKFIQMP--PHCP--------------DSIKKYMSTFIFVDASCRASMTMAIGDF
.|         . |   . .                .||  ||||              . .   |      |.. | ...     .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase F01D4.3.AA UTK 106-338 30 1.1e-66 227.17 In-house 1-271 (296) Show / Hide 
Range on Protein: 106-338
Range on HMM: 1-271/296
Sequence Identity: 30% (82 aa)

VTAGKVLGEGAFGKVFSGTLKLKD--GSSAEVAIKMTKVSAFLSKIKI--KEMMNEAR---FIRNFN-HKNVVRLYGVAHDEQPLYILLELVKGGSLQD-
|  |. ||.|||| |. ....  .  .  . ||.|  ...|.  . .    . |.|||   .  .|. | ||.||.||  .|.|..|..|. ..|.|.. 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

---HMKKAKATGTVVPIAEKVRFCIGAARGIEYLHQNNCIHRDIAARNCLLSEK--------EVKITDFG---LSRNGPS-----------YKIKA-ACK
   | ... | .. .   ... ..   ||| .|||. ...|||.||||||. .          .|| |||   .||. ..           |  .. ...
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

LPVKWLAPETLSSL-CFTFATDVYSWGITCYEVFADGAEPYEGIPNATVKADVLNNKFIQMPP--HCPDSI
.|..| ||| | .   ||...||.|.|..|.|... |. ||.|. |. | . |.|    .||.  .||...
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPV
Kinase F01D4.3.AA TK-Unique 106-344 25 4.5e-51 174.36 In-house 1-275 (294) Show / Hide 
Range on Protein: 106-344
Range on HMM: 1-275/294
Sequence Identity: 25% (70 aa)

VTAGKVLGEGAFGKVFSGTLKLKD-GSSAEVAIKMTKVSAFLSKIKIKEMMNEARFIRNFN-HKNVVRLYGVAHDEQ-PLYILLELVKGGSLQDHMKKAK
.. |.|.|||||| |. |... .. .... . .  ... . ... . .....|... ..   |.|.|...|.  . . | .|..| . .|.||.. .. .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

A---TG-------------TVVPIAEKVR------FCIGAARGIEYLHQ--NNCIHRDIAARNCLLSE-KEVKITDFGLSR----NGPSYKIKAACKLPV
    ..             .  |  | .       |... |.| |||..   ...|||..|||.||.| |..||.|||..|    ||.  ...   ..|.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWLAPETLS---SLCFTFATDVYSWGITCYEVFADGAEPYEGIPNATVKADVLNNKFIQMPPHC-PDSIKKYMST
.|.||| |.     ..|  .||.| |.. .|.|  || || |.|.. .  .. . .  . |.|| .. . . |..
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKS
Kinase F01D4.3.AA Axl 106-361 33 2.9e-49 169.99 In-house 1-267 (267) Show / Hide 
Range on Protein: 106-361
Range on HMM: 1-267/267
Sequence Identity: 33% (90 aa)

VTAGKVLGEGAFGKVFSGTLKLKDGSSAEVAIKMTKVSAFLSKIKIKEMMNEARFIRNFNHKNVVRLYGVAHDEQP------LYILLELVKGGSLQDHM-
.. ||.|||| || |  | ||  |||.  ||.|| |. . ...  | | . ||  ...|.| ||.|| ||.   .         ..|  .| | |  .. 
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKI-DICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLL

-KKAKATGTVVPIAEKVRFCIGAARGIEYLHQNNCIHRDIAARNCLLSEK-EVKITDFGLSR---NGPSYKIKAACKLPVKWLAPETLSSLCFTFATDVY
  . .     .|.   |.| .  | |.||| . | ||||.|||||.| |   | . |||||.   .|  |.   . |.||||.| | |    .|   ||.
YSRLGDQPFYLPLQMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQGCIAKMPVKWIAIESLADRVYTSKSDVW

SWGITCYEVFADGAEPYEGIPNATVKADVLNNKFIQMPPHCPDSIKKYMSTFIFVDASCRASMTMAIG
..|.| .|.   |  || |. |. .   ... . .. |. | | . . |.    .|   | | .    
AFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQPEDCMDELYDLMYQCWEADPKDRPSFSVLRE
Kinase F01D4.3.AA Src 106-338 32 1.7e-47 159.4 In-house 1-229 (255) Show / Hide 
Range on Protein: 106-338
Range on HMM: 1-229/255
Sequence Identity: 32% (78 aa)

VTAGKVLGEGAFGKVFSGTLKLKDGSSAEVAIKMTKVSAFLSKIKIKEMMNEARFIRNFNHKNVVRLYGVAHDEQPLYILLELVKGGSLQDHMKKAKATG
..  . ||.| || |. |. .     . .||.|  |        . .    ||    .. |...|.|| |  .| | ||  |. . |||.|  || . .|
IKLCRKLGQGQFGEVWMGYWN----GNTKVAVKTLKPGT----MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK-DGEG

TVVPIAEKVRFCIGAARGIEYLHQNNCIHRDIAARNCLLSEKE-VKITDFGLSRNGP----SYKIKAACKLPVKWLAPETLSSLCFTFATDVYSWGITCY
  ... . . .    |.| .|| ..| |||| |||| | .|.  .|. |||| |        |  .   |.|.|| ||| ..  .||  .|| | ||  .
RHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLT

EVFADGAEPYEGIPNATVKADVLNNKFIQMPPHCPDSI
|..  |  ||.|  |. |   | ..    .|..|||..
EIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDEL
Kinase F01D4.3.AA MLK 106-343 25 3.1e-43 147.86 In-house 1-271 (291) Show / Hide 
Range on Protein: 106-343
Range on HMM: 1-271/291
Sequence Identity: 25% (70 aa)

VTAGKVLGEGAFGKVFSGTLKLKDGSSAEVAIKMTKVSAFLSKIK----IKEMMNEARFIRNFNHKN----VVRLYGVAHDEQP-LYILLELVKGGSLQD
 .  ...|.|.||||..|. . ||..  .||.|. . ..| .| .    ....  |.|  | ..|.|    ....||| ..... ..|..| . |||| .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

HMKKAKATGT----------VVPIAEKVRFCIGAARGIEYLHQNN---CIHRDIAARNCLLS-------EKEVKITDFGLSRNGPSY---KIKAACKLPV
  . |.  .           |.. . .....   |||..|||..     ||||.  .| |..       .. .||.|||.||   .    . ..|  .  
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYA-

KWLAPETL---SSLCFTFATDVYSWGITCYEVFADGAEPYE-GIPNATVKADVLNNK-FIQMPPHCPDSIKKYMS
 | ||| .    .  .. . ||.|||.  .|... . .||. .. .... . | .|.    .|. ||...|| |.
-WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLT-REVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMK
Kinase F01D4.3.AA ALK 106-318 34 3.6e-43 146.87 In-house 1-226 (273) Show / Hide 
Range on Protein: 106-318
Range on HMM: 1-226/273
Sequence Identity: 34% (79 aa)

VTAGKVLGEGAFGKVFSGTLKLKDGSSAEVAIKMTKVSAFLSKIKIKEMMNEARFIRNFNHKNVVRLYGVAHDEQPLYILLELVKGGSLQDHMKKAKATG
.| ...|| |||| |. |  .  .| | . ...|       |. .    ..||  . .||| ||||. |.  ..||..|.||.  || ..  ..    . 
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPYMIVLEYMEGGDMKSFLRECRPHP

T---VVPIAEK--VRFCIGAARGIEYLHQNNCIHRDIAARNCLLSEKE----VKITDFGLSRNG----PSYKIKAACKLPVKWLAPETLSSLCFTFATDV
      ... |   . |   | |  ||  |  ||||||||||||. |.    .|| ||| .|        | .     .||||  || .    ||  |||
ESLQPSQLTMKDLLQCCCDVAQGCHYLEENHFIHRDIAARNCLLTCKGPGRVAKIADFGMARDITYRADYYRKGGRAMMPVKWMPPEAFMDGIFTSKTDV

YSWGITCYEVFADGAEPYEGIPNATV
 |.|. | |.|  |  || |  |  |
WSFGVLCWEIFSLGYMPYPGRHNQEV
Kinase F01D4.3.AA Frk 106-342 32 1e-42 145.75 In-house 1-235 (260) Show / Hide 
Range on Protein: 106-342
Range on HMM: 1-235/260
Sequence Identity: 32% (80 aa)

VTAGKVLGEGAFGKVFSGTLKLKDGSSAEVAIKMTKVSAFLSKIKIKEMMNEARFIRNFNHKNVVRLYGVAHDEQPLYILLELVKGGSLQDHMKKAKATG
.   . || | ||.|. |    .    . ||.|  |  .    .  .... ||. ...  |  ...|| |   |.|.||. ||.. ||||....  . .|
IQLIRRLGSGQFGEVWEGLWNNT----TPVAVKTLKPGT----MDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKG

TVVPIAEKVRFCIGAARGIEYLHQNNCIHRDIAARNCLLSEKE-VKITDFGLSR-----NGPSYKIKAACKLPVKWLAPETLSSLCFTFATDVYSWGITC
  . . . |      | |. || . | ||||.|||| |. |.  .|| |||| |     |   |  .   ..|.|| |||   .  ||   ||.|.||  
RQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILL

YEVFADGAEPYEGIPNATVKADVLNNKFIQMPPHCPDSIKKYM
.|.   |  || |. || |   | ..  .  || ||  . . |
TEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIM
Kinase F01D4.3.AA TKL 112-340 19 2.4e-42 146.98 In-house 1-341 (364) Show / Hide 
Range on Protein: 112-340
Range on HMM: 1-341/364
Sequence Identity: 19% (68 aa)

LGEGAFGKVFSGTLKLKDGSS------AEVAIKMTKVSA-FLSKIKIKE-----------------MMNEARFI------RNFNHKNVVRLYGVAHDEQP
.|.|.||.|. |...  .|         .||.|. |.    .. ....|                 . .. ...      ....| |.|...|.. ....
IGSGGFGEVYKGKWRGWGG-KCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

-------------LYILLELVKGGSLQDHMKKAKATGTVVPIAEKVRFCIGAARGIEYLHQNN--------CIHRDIAARNCLLSEKE------------
             |.|  |...|||| ...           .  ..|.....|||..|||..|         ||||.  .|.|. |.             
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---VKITDFGLSRNGPSYK--------------------IKAACKLPVKWLAPETLSSL----------------CFTFATDVYSWGITCYEVFA--DGA
   .||.||||||.    .                     .  .     |.||| |                    .. ..||||.||  .|...     
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR--

EPYEGIPNATVK---------ADVLNNKFIQMPP-------------HCPDSIKK
 ||...|. ...         . | ...    .|             .||.|.||
-PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKK
Kinase F01D4.3.AA S_TKc 106-369 23 9.3e-41 142.64 SMART 1-231 (231) Show / Hide 
Range on Protein: 106-369
Range on HMM: 1-231/231
Sequence Identity: 23% (65 aa)

VTAGKVLGEGAFGKVFSGTLKLKDGSSAEVAIKMTKVSAFLSKIKIKEMMNEARFIRNFNHKNVVRLYGVAHDEQPLYILLELVKG--GSLQDHMKKAKA
 . ....|.||||||. .. |    .  .||||. |          . ...| .  .. .|.|.|.||.| .| . ||. .|.. |  |.| |..|| . 
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

--TGTVVPIAEKVRFCIGAARGIEYLHQNNCIHRDIAARNCLLSEKEVKITDFGLSRNGPSYKIKAACKLPVKWLAPETLSSLCFTF-ATDVYSWGITCY
  .. . |  .  ...   ....||.|... ||||.   | ||.| ..||.||||.|          .     ..||| |    ... . |..| |.. |
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EVFADGAEPYEGIPNATVKADVLNNKFIQMPPHCPDSIKKYMSTFIFVDASCRASMTMAIG---DFERMTVM
| .. |  |..   .  .  ...           ... |  ..    .| . | .   |     |   .  .
EMLC-GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase F01D4.3.AA Pkinase 106-303 24 7.8e-32 113.64 Pfam 1-206 (293) Show / Hide 
Range on Protein: 106-303
Range on HMM: 1-206/293
Sequence Identity: 24% (53 aa)

VTAGKVLGEGAFGKVFSGTLKLKDGSSAEVAIKMTKVSAFLSKIKIKEMM-NEARFIRNFNHKNVVRLYGVAHDEQPLYILLELVKGG----SLQDHMKK
 . |...|.|.||.|. .. |       .||.|  |..   |. ..     .|..  ...||.|.||||.. .|.. .|. .|.. ||    .| |... 
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

AKATGTVV--PIAEKVRFCIGAARGIEYLHQNNCIHRDIAARNCLLS-EKEV----KITDFGLSRN--GPSYKIKAACKLPVKWLAPETLS-SLCFTFAT
    ....  .  |  ...   .||.||.|....||||.   |.|.. . ..    ||.||||..     ..           ..||| .  .   . . 
--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVYSWGITCYEVF
|..| |...||..
DMWSCGCILYEML