Gene F09C12.2 (Nematode worm)

F09C12.2

Species: Nematode worm
Alias: CE02602, aSWK202, F09C12.2
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: II:-2.03, WormBase Physical Map location: II: 5110008-5114105,

Classification

Group: CMGC
Family: MAPK
Subfamily: MAPK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
F09C12.2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 299 Kinase domain by global Sugen HMM Fasta, JSON
F09C12.2.AA Protein Genbank 691 None Fasta, JSON

Protein domain

Protein domains of F09C12.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase F09C12.2.AA MAPK 44-342 44 1.6e-169 569.51 In-house 1-328 (328) Show / Hide 
Range on Protein: 44-342
Range on HMM: 1-328/328
Sequence Identity: 44% (147 aa)

YLAQENLGAGAFGVVCRAIDSK------LNKQVAIKKITRVFKNQSTAKCALREIRITREL-SHENIINSTDVLMRES----GSG---QDIYIVMDLMET
|  ....| ||.|||| ||| .       .|.|||||| |.| |.  .|...|||.. |..  |||||.  |... |     .|    .||||||.||||
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLLSVLKSNQTLNEKHFQYFFYQILKG--LKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSRSGPSTKTTPNTSPNAHIS---GDLSQYVSTLWYRA
||  ..||.|.|...|.|||.||||.|  |||.|||..|||||||.|.|.||.| |||.|||..||  .... .. .... ..   .....||.| ||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDP-HCFQKMHMTEYVATRWYRA

PEILLS--MGEYDTQVDIWSAGCILAEMLL-LRPIFTGTDSYSQIQLLIEYLGTPDEQVIRRIK-SPSIRDYISSFG--PKTPL-PFTAMFPN----ASI
|||.|.  . .|...||.||.|||.||||   .|.| |.|.  |..| .|.||||.|..|..|. |.. |.||.|.|  ||.|  |.. ||||    |. 
PEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANP

EARNIVSKMLQISPWKRFSAEQLLEEPFV
.|.. ..|||...|.|| ..|. |. |..
QAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase F09C12.2.AA ERK 44-342 42 1.6e-127 429.94 In-house 1-307 (307) Show / Hide 
Range on Protein: 44-342
Range on HMM: 1-307/307
Sequence Identity: 42% (133 aa)

YLAQENLGAGAFGVVCRAIDSK-----LNKQVAIKKITRVFKNQSTAKCALREIRITRELS-HENIINSTDVLMRESG-SGQDIYIVMDLMETDLLSVLK
|   . .| ||.|||| ||| .      .. ||||||...| .   .| .||||.. | .  |||||.  |..| .|  .  |||.| .||||||  . .
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPEQYNDIYCVEELMETDLHQIIN

SNQTLNEKHFQYFFYQILKGLKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSR---SGPSTKTTPNTSPNAHISGDLSQYVSTLWYRAPEILLSMGE
| |.|...|.||| |||| ||||.|||..||||||| |.|.|..| |||.||| .|   ....  ..         ......||.| |||||||.||  .
SQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHE-------CNQNFMTEYVATRWYRAPEIMLSWQK

YDTQVDIWSAGCILAEMLLLRPIFTGTDSYSQIQLLIEYLGTP-DEQVIRRIKSPSIRDYISSFGP--KTPLPFTAMFPNAS--IEARNIVSKMLQISPW
|.. .||||.|||.||||  .|.| | |.  ||.. ....||| .|. ...|.|.  ..||....   ..| |.  .||||.   .| .  .|||.. | 
YTKAMDIWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPD

KRFSAEQLLEEPFV
|| ..|. || |. 
KRITVEECLEHPYF
Kinase F09C12.2.AA CMGC 44-342 25 1.4e-125 414.99 In-house 1-513 (513) Show / Hide 
Range on Protein: 44-342
Range on HMM: 1-513/513
Sequence Identity: 25% (129 aa)

YLAQENLGAGAFGVVCRAID--------------SKLNKQVAIKKITRVFKNQSTAK----------CALREIRITRELS-----------------HEN
|   . .| |..|||....|               . |..|||||| ..| .. .||           |||||.| ..|.                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IINSTDVLMRES--GSGQ-----------DIYIVMDLMETDLLSVLKSNQ---------TLNEKH------------FQYFF------YQILKGLK--YL
|..  |.....   |...           ..|.|...|..||. ..|.||          |.| |             .||.      ||||.|||  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSAG--IIHRDLKPANLLLNEDCSL--------------------KIADFGMSR--SGPSTKTTPNTSP--------NAHISGDLSQYVSTLWYRAPEIL
||..  ||||||||.|.|.|..| |                    ||.|||..|  . .| ...  . .        . ...  ...||.|.||||||||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDD-KPNRPYTHYVVTRWYRAPEIL

LSMGEYD---------TQVDIWSAGCILAEMLL--------LRPIFT-----------GTDSYSQIQLLIEYLGTP----------------DEQVIRRI
|....|.         |..|.||.|||.|||..        ..|.|            |.. . |... .. ||||                .|. . .|
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

K--------------------SPSIRDYISS---FGPKTPLPFTAMFPN-----------------------------------ASIEARNIVSKMLQIS
|                    |.. | ||.|   |... | |.. .||.                                   .. .|.. ..||||. 
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

PWKRFSAEQLLEEPFV
| || .||| |. |. 
PDKRITAEQALQHPYF
Kinase F09C12.2.AA MAPK-Unclassified 44-192 57 3.5e-111 375.68 In-house 1-157 (575) Show / Hide 
Range on Protein: 44-192
Range on HMM: 1-157/575
Sequence Identity: 57% (90 aa)

YLAQENLGAGAFGVVCRAIDSKL-NKQVAIKKITRVFKNQSTAKCALREIRITRELSHENIINSTDVLMRESGSG---QDIYIVMDLMET---DLLSVLK
|..|.|.|.||.|.||||.|.|. |.||||||....|.|....|..||||||.|.|.|.|||...|.........   .|||||||.|.|   ||....|
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLNHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQIIK

SNQ-TLNEKHFQYFFYQILKGLKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSR
||| .....|.||||||||.||||||||.||||||||.|||.|.|||..|.||||||
SNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSR
Kinase F09C12.2.AA p38 44-342 40 7.89999999999e-105 354.56 In-house 1-289 (289) Show / Hide 
Range on Protein: 44-342
Range on HMM: 1-289/289
Sequence Identity: 40% (123 aa)

YLAQENLGAGAFGVVCRAIDSKLNKQ---VAIKKITRVFKNQSTAKCALREIRITRELSHENIINSTDVLMR---ESGSGQDIYIVMDLMETDLLSVLKS
|   . .| ||.| || |.|.. ...   |||||. | |     || . ||.|  . . |||.|   ||      .  . ||.|.|. .|..||  ..|.
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMKC

NQTLNEKHFQYFFYQILKGLKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSRSGPSTKTTPNTSPNAHISGDLSQYVSTLWYRAPEILLSMGEYDTQ
 |.|.. | |.  ||||.|||| |||||||||||| |. .|||| |.| ||| .|               |   .. .|| | |||||||.|. ..|.  
-QRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR---------------HCDDEMTGYVATRWYRAPEIMLNWMHYTQT

VDIWSAGCILAEMLLLRPIFTGTDSYSQIQLLIEYLGTPDEQVIRRIKSPSIRDYISSFGPKTPLPFTAMFPNASIEARNIVSKMLQISPWKRFSAEQLL
||||| |||.||..  |. | |.|  .|.| ... .||||| .. .|.| . | || |  . .   |. .|..|.  | .   |||.. | || .||. .
VDIWSVGCIMAELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAM

EEPFV
. |. 
QHPYF
Kinase F09C12.2.AA ERK5 44-342 41 1.3e-100 340.58 In-house 1-295 (295) Show / Hide 
Range on Protein: 44-342
Range on HMM: 1-295/295
Sequence Identity: 41% (126 aa)

YLAQENLGAGAFGVVCRAIDSKLNKQVAIKKITRVFKNQSTAKCALREIRITRELSHENIINSTDVLMRESGSG--QDIYIVMDLMETDLLSVLKSNQTL
|   | .| ||.|||| |.  |  .|||||||   |    .||  .||..| |   |.|||   |.|| .   .  .|.|.|.|||| ||  .. ||| .
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFRHDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQPF

NEKHFQYFFYQILKGLKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSRSGPSTKTTPNTSPNAHISGDLSQYVSTLWYRAPEILLSMGEYDTQVDIW
   |  || ||||.||||.||| .|||||||.||| || | ||| |||| | | .|      ||. |    . .|| | ||||||...|. .|   .|.|
TLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMAR-GLCT-----FSPDKHQMF-MTEYVATRWYRAPELMFSSHDYTQAIDVW

SAGCILAEMLLLRPIFTGTDSYSQIQLLIEYLGTPDEQVIRRIKSPSIRDYISS-FGPKTPLPFTAMFPNASIEARNIVSKMLQISPWKRFSAEQLLEEP
| |||. ||.  | .| |     |.||... ||.|  ..|. . .  .. |. . | ...| ..  ..| |   | .....||   | .| .. . |  |
SVGCIFGEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYPKADRQALDLLARMLRFEPSERITVNKALQHP

FV
|.
FL
Kinase F09C12.2.AA ERK7 44-342 38 1.6e-96 326.96 In-house 1-292 (292) Show / Hide 
Range on Protein: 44-342
Range on HMM: 1-292/292
Sequence Identity: 38% (114 aa)

YLAQENLGAGAFGVVCRAIDSKLNKQVAIKKITRVFKNQSTAKCALREIRITRELS-HENIINSTDVLMRESGSGQDIYIVMDLMETDLLSVLKSNQTLN
|. .. || ||.|.| .|.| .  . ||.|||   |.||  |    ||| . .|.  |.|||   .|.  .    .|||.| . |||||  | .  . | 
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRAD--NDRDIYLVFEFMETDLHAVIRKGNILK

EKHFQYFFYQILKGLKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSRSGPSTKTTPNTSPNAHISGDLSQYVSTLWYRAPEILLSMGEYDTQVDIWS
. | || .||.|. .||.||. .|||||||.|.||. .| .|..|||. ||  ...        .   ..|  || | |||||||||.  .|   || ||
DIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEY------DEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWS

AGCILAEMLLLRPIFTGTDSYSQIQLLIEYLGTPDEQVIRRIKSPSIRDYISSFGPKTPLPFTAMFPNASIEARNIVSKMLQISPWKRFSAEQLLEEPFV
 ||||.|||  .|.| ||    || . .| .. | .. |  |.|      ... . . . .. .|.|... .| ... ..|.  | || .||| |. |.|
IGCILGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase F09C12.2.AA S_TKc 44-342 28 5.4e-95 322.81 SMART 1-231 (231) Show / Hide 
Range on Protein: 44-342
Range on HMM: 1-231/231
Sequence Identity: 28% (91 aa)

YLAQENLGAGAFGVVCRAIDSKLNKQVAIKKITRVFKNQSTAKCALREIRITRELSHENIINSTDVLMRESGSGQDIYIVMDLMET---DLLSVLKSNQT
|   . .| ||||.|..... | ...||||.|          . ..|||.| ..  |.||..  ||        ...|.||.....   ||....|....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGR

------LNEKHFQYFFYQILKGLKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSRSGPSTKTTPNTSPNAHISGDLSQYVSTLWYRAPEILLSMGEY
      ..| | ....|||...|.|.|| |||||||||.|.||.|   .||.|||..|                     . .. |.||.|||.|     |
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------TTFCGTPWYMAPEVL----GY

DT-QVDIWSAGCILAEMLLLRPIFTGTDSYSQIQLLIEYLGTPDEQVIRRIKSPSIRDYISSFGPKTPLPFTAMFPNASIEARNIVSKMLQISPWKRFSA
..  .|.|| ||||.|||  .| |       |.|.... .|                                     | ||.....|.||  | || .|
GKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA

EQLLE-------EPFV
 ..|.        |..
-EALQDEWDIKCHPWF
Kinase F09C12.2.AA MAPK-Unclassified 193-342 38 1.5e-91 310.46 In-house 385-575 (575) Show / Hide 
Range on Protein: 193-342
Range on HMM: 385-575/575
Sequence Identity: 38% (74 aa)

SGPSTKTTPNTSPNAHISGDLSQYVSTLWYRAPEILLSMGEYDTQVDIWSAGCILAEMLLL-----------RPIFTGTD--------------------
.....|.........|......|||.|.|||||||.|||.||||||||||.|||.|||...           ||.|.|.|                    
CTKNKKQKHKQINDCHHCYHMTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHS

SYSQIQLLIEYLGTPDEQVIRRIKSPSIRDYISSFGPKTPLPFT-AMFPNAS---------IEARNIVSKMLQISPWKRFSAEQLLEEPFV
...||.....|||.|.|.....|...|.|.||.||..|||..|| .||..|.         .|....|.||||..||||..|.|.||.|..
HQDQIKMIFDYLGMPPEEDCNFITCDSARKYIQSFKCKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase F09C12.2.AA ERK1 44-342 43 8.5e-91 307.95 In-house 1-289 (289) Show / Hide 
Range on Protein: 44-342
Range on HMM: 1-289/289
Sequence Identity: 43% (131 aa)

YLAQENLGAGAFGVVCRAIDSKLNKQVAIKKITRVFKNQSTAKCALREIRITRELSHENIINSTDVLMRES-GSGQDIYIVMDLMETDLLSVLKSNQTLN
|.  . .| ||.|.|| |.|   ...||||||   |  |   .  ||||.|     ||||||  |..  ..  . .|.||| .||||||  .||. | | 
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKIS-PFEHQTYCQRTLREIKILTRFKHENIINIQDIIRADTIEQMRDVYIVQCLMETDLYKLLKT-QHLS

EKHFQYFFYQILKGLKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSRSGPSTKTTPNTSPNAHISGDLSQYVSTLWYRAPEILLSMGEYDTQVDIWS
  |  || ||||.||||.||| ..||||||.|||||  | ||| |||. |          . |.    | |  || | |||||||.|    |   .||||
NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARI---------ADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWS

AGCILAEMLLLRPIFTGTDSYSQIQLLIEYLGTPDEQVIRRIKSPSIRDYISSFGPKTPLPFTAMFPNASIEARNIVSKMLQISPWKRFSAEQLLEEPFV
 ||||||||  |||| |     |. ...  || | .. .. |     | |. |   |. .|.  .||.|   |  .. |||   | ||   |. |  |..
VGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPYL
Kinase F09C12.2.AA CDK 44-342 30 6.1e-85 271.68 In-house 1-284 (284) Show / Hide 
Range on Protein: 44-342
Range on HMM: 1-284/284
Sequence Identity: 30% (100 aa)

YLAQENLGAGAFGVVCRAIDSK-----LNKQVAIKKITRVF-----KNQSTAKCALREIRITRELSHENIINSTDVLMRESGSG-------QDIYIVMDL
|   | .| |..||| .|.| .      .. ||.|||         .       |.||| . .|| |.||..  || . .. .          .|.|.. 
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

METDLLSVLKSNQTLNEKHFQYFFYQILKGLKYLHSAGIIHRDLKPANLLLNEDCS-----LKIADFGMSRSGPSTKTTPNTSPNAHISGD----LSQYV
|..|| ....          . ...|.|.|| |.|| .|.||||||.|.|.|.. .     ||||||| .|   . .           | .    ..  |
MDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQ---------MS-EPNRTYTHEV

STLWYRAPEILLSMGEYD--TQVDIWSAGCILAEMLL---LRPIFTGTDSYSQIQLLIEYLGTPDEQVIRRIKSPSIRDYISSFGPKTPLPFTAMFPNAS
 ||||||||.||   .|.  |..|.||.|||.|||..    .|.| |.    |. . .. .|||.|..   ..  .  ||                    
VTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVT--KLPDY--------------------

IEARNIVSKMLQISPWKRFSAEQLLEEPFV
    .  .|||.  | ||.|||| |. |. 
----DLLNKMLCYDPKKRISAEQALQHPYF
Kinase F09C12.2.AA Pkinase 44-342 29 1.7e-84 291.84 Pfam 1-293 (293) Show / Hide 
Range on Protein: 44-342
Range on HMM: 1-293/293
Sequence Identity: 29% (93 aa)

YLAQENLGAGAFGVVCRAIDSKLNKQVAIKKITRVFKNQSTAKCALR--EIRITRELSHENIINSTDVLMRESGSGQDIYIVMDLMET-----DLLSVLK
|   . .|.|.||.|..... . .|.||.|.| .. .. .  . ..|  ||.| ..|.|.||.   |. ..    ...||.||...|      || ....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLFDYIS

--SNQTL--NEKHFQYFFYQILKGLKYLHSAGIIHRDLKPANLLLNEDCSL----KIADFGMSRSGPSTKTTPNTSPNAHISGDLSQYVSTLWYRAPEIL
  .. ..   |.. . ..||||.||.|.|| |||||||||.|.|..... .    ||.||| ..                 .. .. .. |.||.|||..
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----------Y-NNS-MTTFCGTPWYMAPEVI

LSMGEYDTQVDIWSAGCILAEMLLLRPIFTGT----DSYSQIQLLIEYLGTPDEQVIRRIKSPSIRDYISSFGPKTPLPFTAMFPNASIEARNIVSKMLQ
..  .|.. ||.||.||||.|||. ||.| |     . ..|.|.. . .|.| .  .    |.| .  ..    .    ..   .|.| |.. .....|.
RGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--F-HWTF-HNWSEECKDFIKWCLC

ISPWKRFSAEQLLEEPFV
  | || .|||.|. |..
KDPKKRPTAEQILQHPWF
Kinase F09C12.2.AA CDC2 44-342 33 3.3e-81 249.25 In-house 1-301 (301) Show / Hide 
Range on Protein: 44-342
Range on HMM: 1-301/301
Sequence Identity: 33% (106 aa)

YLAQENLGAGAFGVVCRAIDSKLNKQVAIKKITRVFKNQSTA---KCALREIRITRELS-HENIINSTDVLMRESGSGQDIYIVMDLMETDLLSVLK---
|   | .| | .||| ...| . |..||.||| |.  ..        |.||| .  ||  |.||.   ||..      . .|.| . .. ||   ..   
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKI-RLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-----NKLYMVFEYLDMDLKKYMDMSI

-SNQTLNEKHFQYFFYQILKGLKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSR--SGPSTKTTPNTSPNAHISGDLSQYVSTLWYRAPEILLSMGE
 .|. . .   . ..||||.|. ..|. .|.|||||| |.|.... ..|||||| .|  . |. . |..              | |||||||||||    
PKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTE------------HEVVTLWYRAPEILLGCKR

YDTQVDIWSAGCILAEM---LLLRPIFTGTDSYSQIQLLIEYLGTPDEQVIRRIKSPSIRDYISSFGPKTPLPFTAMFPN---------ASIEARNIVSK
|.| ||.|| |||.|||      .|.| |     |.    ..||||.||    ..  .  || ..|.  .|  .. ..||         .  |.. . ..
YSTPVDMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVT--QLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQ

MLQISPWKRFSAEQLLEEPFV
|||. | || ||.. |. |. 
MLQYDPQKRISAKEALQHPYF
Kinase F09C12.2.AA Pkinase_Tyr 44-192 32 3.1e-19 65.79 Pfam 1-159 (270) Show / Hide 
Range on Protein: 44-192
Range on HMM: 1-159/270
Sequence Identity: 32% (52 aa)

YLAQENLGAGAFGVVCRAIDS----KLNKQVAIKKITRVFKNQST--AKCALREIRITREL-SHENIINSTDVLMRESGSGQDIYIVMDLMET-DLLSVL
    . ||.||||.|....      . . .||.|.. .    ..    .  .||..| ..| .|.||..   | .......  ||||| .|.  |||. |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYL

KS----NQTLNEKHFQYFFYQILKGLKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSR
..    .| |. |.   . .|| ||. ||.| ..|||||   | |..|.   ||.|||..|
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase F09C12.2.AA TyrKc 44-340 24 6.5e-16 34.6 SMART 1-280 (280) Show / Hide 
Range on Protein: 44-340
Range on HMM: 1-280/280
Sequence Identity: 24% (77 aa)

YLAQENLGAGAFGVVCRAIDSKLNKQVAIKKITRVFKNQSTAKCALREIRITREL--SHENIINSTDVLMRESG---SGQDIYIVMDLMET-DLLSVLKS
    . || ||||.|.... .    |||.|..          .  .||.|| ..|  .|.||..   | . ...   . . ..||| .|.  ||.. |..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NQT-LNEKHFQYFFYQILKGLKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSRSGPST-KTTPNTSPNAHIS--GDLSQYVSTLWYRAPEILLSMGE
..  |. |.. .| .|| .|  |||| ..|||||   | |..|.   ||.|||.|| . .  ..    |     .  .. . ..  .   ||| .   |.
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGK

YDTQVDIWSAGCILAEMLLLRPIFTGTDSYSQIQLLIEYLG-----TPDEQVIRRIKSPSIRDYISS-----FGPKTPLPFTAMFPNASIEARNIVSKML
. |. |.|| |  . |      |||  ..         | |      ....||...|.   ..   .     |            . .. |  .| ..  
FTTKSDVWSFGVCMWE------IFTYGQQP--------YPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF------------VCCPDEMYQIMKQCW

QISPWKRFSAEQLLEEP
.  | .| . ... |. 
HEDPEDRPTFSEIHECF
PGAM F09C12.2.AA PGAM 493-626 19 2.3e-12 45.68 Pfam 41-175 (175) Show / Hide 
Range on Protein: 493-626
Range on HMM: 41-175/175
Sequence Identity: 19% (31 aa)

AQMIGRG--LLMTDNTPDVIYCSPSLRCIQTATW-VRE-MSGSKALLRVEPGLFENFH-------------------YPHGVPRFISQLQRHVFPVDKTF
|.  |.   | . .  .|.||||| .||.||| . . |   |... ....|.| | ..                   ||        .  |  .  ....
ARQLGKWLQLKEHGIPFDHIYCSPLKRCQQTAEIIIAEMHLGCWIPIIIDPRLREWHFGQEDWPCEEGMTWDEIWEQYP--------EEWR-WWEDPWDY

RPFLSLETVVGKQE--TNDEYNARIQLILNAIADQSEVSTVEKELKV-LVVAHASTVDMA
||        .. |  . ... .|.   ...|.        ...  | |.|.|. .. ..
RPP-------EGGEEESYEDFWERV-PFWEEII--------HPGENVILIVSHGGVIRAL