F09G2.1

Species: Nematode worm
Alias: F09G2.1, aSWK395, CE30744
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: V: 7202858-7208208, WormBase Genetic Map location: V:-1.25,

Classification

Group: TK
Family: KIN6

Sequence

Name Sequence Type Origin Length Description Download
F09G2.1.AA Protein Genbank 971 None Fasta, JSON
F09G2.1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 285 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of F09G2.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase F09G2.1.AA KIN6 529-813 49 1.7e-213 712.26 In-house 1-305 (305) Show / Hide
Range on Protein: 529-813
Range on HMM: 1-305/305
Sequence Identity: 49% (152 aa)

VVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRA----EALDYTDCDCAVKMLPKYATDAAKQEFRHEIELMKNLGFNEHLVNMLGCITVSAKSCLVLEHC
..|..||||||...|.||||.|..|.....||.    |...|.||.|||||||..|...|...|.|||..||.||...||||||||.|.|.|.|||.|.|
IHKDHKLGHGAFCNVYKGKIKGKSPIMQWINRVNMRIEMMRYQDCQCAVKMLPSHADEMAHHDFMHEIAFMKQLGHHPHLVNMLGCVTNSYKPCLVVEYC

CHRDLLRYVKNKK--------------CDLEISRSVDDTIDSHKEFLNFAWQITQGMRFLVDKRIIHRDLAARNILITEQCGMKSAKVSDFGLAILSEPS
||.|||.|..|..              |..|.||..|.....||....|||||..||..|..|..|||||||||.|.||.|.||..|.|||||.......
CHMDLLKYLRNRCQYMMNLDDLGINYHCPDENSRYDDMMCIRHKDLYMFAWQICDGMEYLHSKNCIHRDLAARNVLVTEGCRMKTCKISDFGLCRYPYMD

ENGEVTGSDR-LPIKWLALECLEKAEFSFKSDVWSFGIVIFEMYSLGDVPFAEIE-PTELIAHLKSGARPKFPLLATDKIEEIMSSCWSEKSEERPDFDE
.........| |||||.|.|||...|||.||||||||...|||.||||||..|.. |||.|.|..||.|||.|......|..||.|||.||...||.|.|
QFQYTSKGGRYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKWCPEEIYDIMQSCWQEKPDDRPEFNE

LSKLF
....|
MRMQF

Kinase F09G2.1.AA TyrKc 529-813 29 1.3e-110 374.66 SMART 1-280 (280) Show / Hide
Range on Protein: 529-813
Range on HMM: 1-280/280
Sequence Identity: 29% (93 aa)

VVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRAEALDYTDCDCAVKMLPKYATDAAKQEFRHEIELMKNLG-FNEHLVNMLGCITVS-------AKSCLV
.....|||.||.| |.||.                      ..||||| ..|    ...|..|...|..||  ....|...|..| .          ..|
ITLGKKLGEGAFGEVYKGTWK-------------------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIV

LEHCCHRDLLRYVKNKKCDLEISRSVDDTIDSHKEFLNFAWQITQGMRFLVDKRIIHRDLAARNILITEQCGMKSAKVSDFGLAILSEPS-------ENG
.|...| ||. | .... .            ..|..|.|.||| .||..| .|..|||||||||.|..|.     .|.|||||.   .         .  
MEYMPHGDLKDYLRKHRPK-----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYY

EVTG--SDR--LPIKWLALECLEKAEFSFKSDVWSFGIVIFEMYSLGDVPFAE-----IEPTELIAHLKSGARPKFPLL--------ATDKIEEIMSSCW
 ...  . .  |||.|.|.||. . .|..||||||||....|....|. |  .     ....|.|...|.| |.. |          ..|.. .||..||
RKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCW

SEKSEERPDFDELSKLF
 |. |.|| | |. ..|
HEDPEDRPTFSEIHECF

Kinase F09G2.1.AA Pkinase_Tyr 529-813 32 2.2e-106 360.92 Pfam 1-270 (270) Show / Hide
Range on Protein: 529-813
Range on HMM: 1-270/270
Sequence Identity: 32% (95 aa)

VVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRAEALDYTDCDCAVKMLPKYATDAA--KQEFRHEIELMKNLGFNEHLVNMLGCITVSAKS---CLVLEH
.....|||.||.|.|.||.  |              | |....|||||. .|.. .  ...| .|...||.|| ....|...|..|   ..   ..|.|.
ITFGKKLGEGAFGEVYKGTWKG------------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEY

CCHRDLLRYVKNKKCDLEISRSVDDTIDSHKEFLNFAWQITQGMRFLVDKRIIHRDLAARNILITEQCGMKSAKVSDFGLAILSEPSENG-EVTGSDRLP
..| ||| | ....       . .. .. .   |...||| .|| .| .|..|||||||||.|.||  ..  .|..||||| . .. ..   ..|. .||
MPHGDLLDYLRKHR-------EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NN-VVKICDFGLARDIYNDDYYYRKRGGGKLP

IKWLALECLEKAEFSFKSDVWSFGIVIFEMYSLGDVP-FAEIEPTELIAHL-KSGARPKFPLLATDKIEEIMSSCWSEKSEERPDFDELSKLF
|||.|.||.   .|. ||||||||....|....|. | .... ..|..... ..| | . | ...|.| ..| .|| .. |.|| | |.   .
IKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase F09G2.1.AA TK 529-813 19 5.7e-92 308.56 In-house 1-486 (486) Show / Hide
Range on Protein: 529-813
Range on HMM: 1-486/486
Sequence Identity: 19% (93 aa)

VVKNEKLGHGAYG---HVFKGKIVGVPPAIEKYNRAEA---------LDYTDCDCAVKMLPKYATDAAKQEFR----------------HEIELMKN-LG
..  .|||.|..|    |.||.  | .|  .|......          . . ...||||| . ........|                 .|...|.. ||
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

FNEHLVNMLGCITVSAK------------SCLVLEHCCHRD----LLRYVKNKK---------------------------------------CDLEISR
  ...|...|..| ..              ..|.|...| |    |. | ....                                       |  | ..
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC-PEEQD

SVDD------TIDSHKEFLN-------------------FAWQITQGMRFLVDK------RIIHRDLAARNILITEQCGMK--------SAKVSDFG---
..||      .  ..|..|.                   ..||| .||..| .|      ...||||||||.|..|.   |         .|..|||   
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LAILSEPSENGEVTG------------------------SDRLPIKWLALECLEKAE---------FSFKSDVWSFGIVIFEMYSLGDVPFA---
     ||   .....  ...                        ...|||.|.| |||.. .         |. ||||||||....|....|..|..   
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

--------EIEPTELIAHLKSG--------------ARPKFPLLAT--------------DKIEEIMSSCWSEKSEERPDFDELSKLF
        . ...|.. .|..|               |.. | ...              . ....| .||... |.||.|..| . .
SNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase F09G2.1.AA TK-Unique 529-813 30 3e-71 243.03 In-house 1-294 (294) Show / Hide
Range on Protein: 529-813
Range on HMM: 1-294/294
Sequence Identity: 30% (95 aa)

VVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRAEALDYTDCDCAVKMLPKYATDAAKQEFRHEIELMKNLGFNEHLVNMLGCITVSA-KSCLVLEHCCHR
.. ....| ||.|.|..|...|..         .  | ..|  ||||| ..|||  ||.|  ||..||.||  ...|..||| | |    ....|.|   
LEVGDVIGEGAFGQVWRGEVWGIW---------KHWDKQKC-VAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCG

DLLRYVKNKKCD---------------LEISRSVDDTIDSHKEFLNFAWQITQGMRFLVD--KRIIHRDLAARNILITEQCGMKSAKVSDFGLAI-LSEP
.|. | ......                . ..  ...|.. | ...||||| .|| .|    |.|.||||.|||.|.||    | .|..|||.|  .. .
NLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISP-KDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE---DKVCKICDFGMARDVYTN

SENGEVTGSDRLPIKWLALECLE--KAEF-SFKSDVWSFGIVIFEMYSLGDVPFAEIEPTELIAHLKSGARPKFPLLA-TDKIEEIMSSCWSEKSEERPD
 ..   ... |.||.|.|.| |   .  . . ||||||||....|. .||  |. .. ..... ... | |.. |    .. . ..|.|||... ||||.
GVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPS

FDELSKLF
|... . .
FRQIKHRL

Kinase F09G2.1.AA UTK 529-813 24 7.4e-52 175.69 In-house 1-296 (296) Show / Hide
Range on Protein: 529-813
Range on HMM: 1-296/296
Sequence Identity: 24% (77 aa)

VVKNEKLGHGAYGHVFKGKIV-GVPPAIEKYNRAEALDYTDCDCAVKMLPKYATDAAKQE----FRHEIE---LMKNLGFNEHLVNMLGCITVSAKSCLV
|   ..||.||.| |.|.. .   ... | . .  ...            . |..  ..|    |. |     .||..   .......|  | .   ..|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ------------HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIV

LEHCCHRDLLRYVKNKKCDLEISRSVDDTIDSHKEFLNFAWQITQGMRFLVDKRIIHRDLAARNILITEQ-----CGMKSAKVSDFG---LAILSE----
.|...  ||. |.    ..   .   .... .  . | .||.|  || .|  ....||||||||.|....     | | ..|..|||   .. .      
TEYMENGDLRSYL----RRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHC-MMVCKIADFGRGGMSRRVNTFHF

---PSENGEVTGSD--RLPIKWLALECLEKA-EFSFKSDVWSFGIVIFEMYSLGDVPFAEIEPTELIAHLKSG--ARPKFPLLATDKIEEIMSSCWSEKS
    .|  ... ..  |.||.| | |.| ..  |..||||||||.| .|... | .|....   .... .  |  .|.. |    . . ..| .||    
SNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDP

EERPDFDELSKLF
.|||||..| . .
QERPDFEDLVQQM

Kinase F09G2.1.AA RTKB 657-813 38 1.7e-51 171.89 In-house 112-264 (264) Show / Hide
Range on Protein: 657-813
Range on HMM: 112-264/264
Sequence Identity: 38% (61 aa)

LNFAWQITQGMRFLVDKRIIHRDLAARNILITEQCGMKSAKVSDFGLAILSEPSENGEVTGSDRLPIKWLALECLEKAEFSFKS-DVWSFGIVIFEMYSL
. |. || .|| ||  . .|||||.|||.|.. |    . |..|||.|  ..  .    |. .||||||.| | ...  .. || ||||||.  .|  ||
VDFCHQIACGMAFLHQHNVIHRDLCARNVLVDQQL---HCKICDFGMAREIDHECY--ETTCTRLPIKWMAPESWAHRIYTTKSGDVWSFGVTMWEIFSL

GDVPFAEIEPTELIAHLKSGARPKFPLLATDKIEEIMSSCWSEKSEERPDFDELSKLF
| .|... .  ..  .| || |.  | ..  .. .||  ||..  ..||||||| ..|
GGTPYQQYRNGDIFYWLESGHRLPKPRQMPQAADHIMQMCWQMEAQHRPDFDELVDAF

Kinase F09G2.1.AA Fer 657-814 29 2.4e-49 166.24 In-house 114-283 (283) Show / Hide
Range on Protein: 657-814
Range on HMM: 114-283/283
Sequence Identity: 29% (50 aa)

LNFAWQITQGMRFLVDKRIIHRDLAARNILITE-QCGMKSAKVSDFGLAILSEPSENGEVTG--SDRLPIKWLALECLEKAEFSFKSDVWSFGIVIFEMY
.... |. .||..|  | .||||.||||.|... .   |  |.||||..   .  ..    .  ....||.||| |.... ..|.|.||||||....| .
IRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKK-CKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIF

SLGDVPFAE----IEPTEL----IAH-LKSGARPKFPLLATDKIEEIMS-SCWSEKSEERPDFDELSKLFA
. |. |...    . .|..    ..   |.| ....|. . . | .||  .|| .. |.|| ..|. . . 
TNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK

Kinase F09G2.1.AA Src 572-813 32 7.3e-46 153.78 In-house 27-255 (255) Show / Hide
Range on Protein: 572-813
Range on HMM: 27-255/255
Sequence Identity: 32% (80 aa)

AVKMLPKYATDAAKQEFRHEIELMKNLGFNEHLVNMLGCITVSAKSCLVLEHCCHRDLLRYVKNKKCDLEISRSVDDTIDSHKEFLNFAWQITQGMRFLV
||| | | .|  . . |  |...||.|   |.||...   .       | |  .|  || | |.         . .    . .. . .|.|. .|| .| 
AVKTL-KPGT-MSPEAFLQEAQIMKKLRH-EKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK---------DGEGRHLHLPQLIDMAAQVAEGMAYLE

DKRIIHRDLAARNILITEQCGMKSAKVSDFGLAILSE-PSENGEVTGSDRLPIKWLALECLEKAEFSFKSDVWSFGIVIFEMYSLGDVPFAEIEPTELIA
 ...|||||||||.|. |.     .|| ||||| | .   .. .     ..|||| | |..    |. ||||||||| . |. . | ||    .  | . 
SMNYIHRDLAARNVLVGENN---VCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQ

HLKSGARPKFPLLATDKIEE-IMSSCWSEKSEERPDFDELSKLF
... | |   |    |.. | ||  || .. |.|| |. | . .
QVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL

Kinase F09G2.1.AA FGFR 652-813 36 3.4e-45 151.96 In-house 134-293 (293) Show / Hide
Range on Protein: 652-813
Range on HMM: 134-293/293
Sequence Identity: 36% (60 aa)

SHKEFLNFAWQITQGMRFLVDKRIIHRDLAARNILITEQCGMKSAKVSDFGLAILSEPSENGEVTGSDRLPIKWLALECLEKAEFSFKSDVWSFGIVIFE
. |.   .|.|. .|| .|  ...|||||||||.|.|.   |   |..|||||      .    |.  |||||| |.| |    .  .|||||.|. . |
TQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVM---KICDFGLARDIHCIDYYRKTTNGRLPIKWMAPEALFDRVYTHQSDVWSYGVLLWE

MYSLGDVPFAEIE-PTELIAHLKSGARPKFPLLATDKIEEIMSSCWSEKSEERPDFDELSKLF
   .|. |.  |    || . ||.| |   | . .  |  .| .|| .|...|| | .|   .
IMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL

Kinase F09G2.1.AA VEGFR 654-813 39 3.4e-45 156.45 In-house 173-332 (332) Show / Hide
Range on Protein: 654-813
Range on HMM: 173-332/332
Sequence Identity: 39% (65 aa)

KEFLNFAWQITQGMRFLVDKRIIHRDLAARNILITEQCGMKSAKVSDFGLA---ILSEPSENGEVTGSD--RLPIKWLALECLEKAEFSFKSDVWSFGIV
.. .... |.  ||.||  . .|||||||||||..|    .  | .|||||   | . |     |.  |  ||||||.|.| .    .. .|||||.|..
EDLICYSFQVARGMEFLASRKCIHRDLAARNILLCEN---NVVKICDFGLARHGIYKDPD---YVRKGDQGRLPIKWMAPESIFDKVYTTYSDVWSYGVF

IFEMYSLGDVPFAEIE-PTELIAHLKSGARPKFPLLATDKIEEIMSSCWSEKSEERPDFDELSKLF
  |. ||| .|   .    |..  ||.| | . | ..|  | .|| .||..  |||| |.|| . .
LWEIFSLGGSPYPGVQIDEEFCNRLKDGYRMRAPDYCTPEIYHIMLDCWHKEPEERPHFSELVEHL

Kinase F09G2.1.AA EGFR 572-814 33 8.4e-43 139.83 In-house 32-258 (258) Show / Hide
Range on Protein: 572-814
Range on HMM: 32-258/258
Sequence Identity: 33% (82 aa)

AVKMLPKYATDAAKQEFRHEIELMKNLGFNEHLVNMLGCITVSAKSCLVLEHCCHRDLLRYVKNKKCDLEISRSVDDTIDSHKEFLNFAWQITQGMRFLV
|.|.| .     |..|.  |   |  .  ..||| .||    |    ||     .  || ||.. |          |.| |. . ||.. || .|| .| 
AIKVLREQTGPKANEEMLDEAYVMASVD-HPHLVRLLGVCMHSQ-MQLVTQYMPYGCLLDYVRQHK----------DNIGSQ-HLLNWCVQIAKGMQYLE

DKRIIHRDLAARNILITEQCGMKSAKVSDFGLAILSEPSENGEVTGSDRLPIKWLALECLEKAEFSFKSDVWSFGIVIFEMYSLGDVPFAEIEPTELIAH
..|..||||||||.|.      .  |. ||||| | |. |.     . ..||||.||||...  .  .|||||.|. . |.   |  |.. |.  |    
EHRMVHRDLAARNVLVKS---PNHVKITDFGLAKLLEHDEKEYHAQGGKMPIKWMALECIHHRCYTHQSDVWSYGVTCWELMTFGQKPYDGIPAREIPDL

LKSGARPKFPLLATDKIEEIMSSCWSEKSEERPDFDELSKLFA
|. | | . |   |  .  .| .||   .. || | || . | 
LEKGERLPQPPICTIDVYMVMVKCWMIDEDMRPTFKELYEEFK

Kinase F09G2.1.AA S_TKc 529-815 19 8.6e-31 109.53 SMART 1-231 (231) Show / Hide
Range on Protein: 529-815
Range on HMM: 1-231/231
Sequence Identity: 19% (58 aa)

VVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRAEALDYTDCDCAVKMLPKYATDAAKQEFRHEIELMKNLGFNEHLVNMLGCITVSAKSCLVLEHCCH--
  . .|.|.||.| |.|.. ..                |.  .|.|...        . .| ||...|.    ...|......    . ..|.|.| .  
YEILRKIGKGAFGKVYKCRHKK----------------TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDL

RDLLRYVKNKKCDLEISRSVDDTIDSHKEFLNFAWQITQGMRFLVDKRIIHRDLAARNILITEQCGMKSAKVSDFGLAILSEPSENGEVTGSDRLPIKWL
 ||..| |....         .   .  .   ...|| ... .. ...||||||   |||..|       |..||||| .           .      ..
GDLFDYIKKRGRHGL------RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL---------TTFCGTPWYM

ALECLEKAEFSF-KSDVWSFGIVIFEMYSLGDVPFAEIEPTELIAHLKSGARPKFPLLATDKIEEIMSSCWSEKSEERPDFDELSK-------LFAT
| | |    ... |.|.||.|....||.. |  ||   .. ... ...           ..   .... |.    |.||   |. .           
APEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase F09G2.1.AA Pkinase 529-813 20 1.9e-25 91.09 Pfam 1-293 (293) Show / Hide
Range on Protein: 529-813
Range on HMM: 1-293/293
Sequence Identity: 20% (66 aa)

VVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRAEALDYTDCDCAVKMLPKYATDAAK-QEFRH--EIELMKNLGFNEHLVNMLGCITVSAKSCLVLEHCC
 .. .|.| |..| |.|.. .| .                   ||| ..|  ..  | |. |.  ||..||.|.  .. | .... . . . ..|.|.| 
YHIGRKIGSGSFGCVYKCHHKGTGK----------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFEDKDHIYMVMEYCE

HR----DLLRYVKNKKCDLEISRSVDDTID--SHKEFLNFAWQITQGMRFLVDKRIIHRDLAARNILITEQCGM-KSAKVSDFGLAI---LSEPSENGEV
.     || .|..            ...    | .|  ....|| .|. .. ...||||||   |||| ...    . |..|||||    .   | .  .
GGLYVMDLFDYIST----------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTF

TGSDRLPIKWLALECLE-KAEFSFKSDVWSFGIVIFEMYSLGDVPFAEI----EPTELIAHLKSGAR--PKFPLLAT---------------------DK
.|. .    ..| | .    . . |.|.||.|....||.. |  || .     .  . .. ..   .  ..|.   .                     . 
CGTPW----YMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEE

IEEIMSSCWSEKSEERPDFDELSKL--F
  .....|.  . ..|| .... .   |
CKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase F09G2.1.AA RTKB 529-609 29 8.9e-09 25.74 In-house 1-69 (264) Show / Hide
Range on Protein: 529-609
Range on HMM: 1-69/264
Sequence Identity: 29% (24 aa)

VVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRAEALDYTDCDCAVKMLPKYATDAAKQEFRHEIELMKNLGFNEHLVNMLG
|   ||||.||.| ||.. .            ..   .|   ||.| |.  |   ..|.|. |. .|| ||   ... ..|
VWLGEKLGNGAFGEVFQAWV------------RNRHMNTEQSCAAKVLKPGASYEERQDFCSEMTVMKELGWHPNVIGIIG

Kinase F09G2.1.AA Fer 529-598 26 7.8e-07 19.43 In-house 1-66 (283) Show / Hide
Range on Protein: 529-598
Range on HMM: 1-66/283
Sequence Identity: 26% (21 aa)

VVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRAEALDYTD-------CDCAVKML-PKYATDAAKQEFRHEIELMKN-L
|. ..||| ||.| |.||.            | .   . .       ....||..    ||.. ..|| ||  .|.| .
VTLGKKLGEGAFGEVYKGR------------R-TLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNY

Kinase F09G2.1.AA FGFR 528-610 27 0.000115 11.77 In-house 1-73 (293) Show / Hide
Range on Protein: 528-610
Range on HMM: 1-73/293
Sequence Identity: 27% (23 aa)

LVVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRAEALDYTDCDCAVKMLPKYATDAAKQEFRHEIELMKNLGFNEHLVNMLGC
|..  . || |..| | ..  .|.... .. . .          ||||| . .||        |.| ||  | ..  .| |||
LTL-GKMLGEGCFGQVWMAEAKGIDCDRPEKEIT---------VAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGC

Kinase F09G2.1.AA EGFR 529-546 50 0.000915 8.18 In-house 1-18 (258) Show / Hide
Range on Protein: 529-546
Range on HMM: 1-18/258
Sequence Identity: 50% (9 aa)

VVKNEKLGHGAYGHVFKG
. |  .|| ||.| |.||
LKKVKVLGSGAFGTVYKG

Kinase F09G2.1.AA Src 529-547 36 0.038658 3.01 In-house 1-19 (255) Show / Hide
Range on Protein: 529-547
Range on HMM: 1-19/255
Sequence Identity: 36% (7 aa)

VVKNEKLGHGAYGHVFKGK
.   .||| | .| |..|.
IKLCRKLGQGQFGEVWMGY

Kinase F09G2.1.AA VEGFR 572-636 34 0.07686 2.97 In-house 33-100 (332) Show / Hide
Range on Protein: 572-636
Range on HMM: 33-100/332
Sequence Identity: 34% (24 aa)

AVKMLPKYATDAAKQEFRHEIELMKNLGFNEHL--VNMLGCITV--SAKSCLV-LEHCCHRDLLRYVKNK
|||||   ||   . .   |..... .|   ||  ||.||| |     .  .|  | ||.  |. | . |
AVKMLKEGATASEHRALMSELKMLIHIG--HHLNVVNFLGCCTKNIQKGPLMVIVEYCCFGNLSNYLRTK