Gene F11D5.3 (Nematode worm)

F11D5.3

Species: Nematode worm
Alias: F11D5.3A, CE27950, F11D5.3, F11D5.3a, aSWK332
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: X: 3284456-3293363, WormBase Genetic Map location: X:-11.07,

Classification

Group: TK
Family: DDR

Sequence

Name Sequence Type Origin Length Description Download
F11D5.3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 261 Kinase domain by global Sugen HMM Fasta, JSON
F11D5.3.AA Protein Genbank 797 None Fasta, JSON

Protein domain

Protein domains of F11D5.3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
F5_F8_type_C F11D5.3.AA F5_F8_type_C 40-178 25 2.7e-27 95.93 Pfam 1-140 (140) Show / Hide 
Range on Protein: 40-178
Range on HMM: 1-140/140
Sequence Identity: 25% (37 aa)

QISASSSFDLQSTGP--QHARAHQE-SGSGAWCP-KNQINSLSKEWLQISFSVDTVITSVETQGRFDDGRGMEYATAFKIQYWRPS-LN-AWASYKDDFE
||.|||... .  ..    .. .   . ...|.. |.. |.  ..|.|. .   . ||.|..|.| | |   ......||||      .  | .|||. .
QITASSQWSGYWGNGWPPDNAIDGNGYPNTFWHSQKWS-NNDDPQWIQVDLGKPYKITGVVYQWRQDGGN--GWVKKYKIQYSNDGGDESNWTTYKDHDG

LETIPANNDTEHAIRRHLDRAIIARRIRIVPV-SNSTRTVCMRVEV
  . ..| |   . ..... .|.|| .||.|.  |..   .||.|.
-KVFYGN-DND-PVKNMFFPPIKARYVRIHPTSWNNHNWWAMRWEF
FA58C F11D5.3.AA FA58C 24-181 22 2.5e-22 81.41 SMART 1-199 (199) Show / Hide 
Range on Protein: 24-181
Range on HMM: 1-199/199
Sequence Identity: 22% (46 aa)

ECSHQLGMSNRKIRDEQISASSS------FDLQSTGPQHARAHQESG-----SGAWCPKNQIN------SLSKEWLQISFSVD-TVITSVETQGRF----
|| . ||| . .| |.|| ||||      . .. ..| .|| ... .      .||||..  .          .|... .    . .| | |....    
ECNEPLGMEGGHIPDWQITASSSHYWNRDMPWWYWWPHIARLNGNGSNHDYWDNAWCPWKNDYEDWIFDYHCPHWWLVDLGRKTHRVTGV-TITGRRRRG

---DDGRGMEYATA-FKIQYWRPSLN-----AWASYKDDF------ELETIPANNDTEHAIRRHLDRAIIARRIRIVPVSN------STRTVCMRVEVFG
   ... ...|    .|. ..|. .      .|  |||        . .....|.| .|  . .......|| |||.|. .        ...|||.|..|
HGWGHDDWWTYYWMMYKD-DRRDNNERQNGHTWTTYKDFWIEHGTGNSMVFYGNWDNNHPWHNMFHPPMVARYIRIWPTWWNTNATGWHHNYCMRWELYG

C
|
C
F5_F8_type_C F11D5.3.AA F5_F8_type_C 255-332 10 6.021963 1.77 Pfam 46-140 (140) Show / Hide 
Range on Protein: 255-332
Range on HMM: 46-140/140
Sequence Identity: 10% (11 aa)

LAFEFSELRNISGILIHTSNEFKKSAKAFSSATVLFSING--K-DFSDTIV----------------HFNNPEDTESEVPRWIRIPV-----NNRIAKVA
. . . . ..|.|. .   . . .     .. .. .| .|  . .. .                   .|..| ..     |..|| .     .|..| ..
IQVDLGKPYKITGVVYQWRQDGGN--GWVKKYKIQYSNDGGDESNWTTYKDHDGKVFYGNDNDPVKNMFFPPIKA-----RYVRIHPTSWNNHNWWAMRW

KI
 .
EF
Kinase F11D5.3.AA DDR 527-785 44 2e-181 609.01 In-house 1-306 (306) Show / Hide 
Range on Protein: 527-785
Range on HMM: 1-306/306
Sequence Identity: 44% (137 aa)

LICVSRIGQGEFGEVDLCQLENRK------------------VAVKKLHG-ISQADEFSFHREIRVLGSLK-HPNVVEVVGVCTIQKPILCIMEYMEN-G
||.|..||.|.||||.||..|...                  ||||.|.. ........||.||......| |||.|..|||||...|...||||||| |
LIFVEKIGEGQFGEVHLCEVEGMQDYIEFDFHCDVHKGHPTLVAVKMLRPDACKHARNDFHKEIKCMSQCKRHPNIVRLVGVCTQDEPYCMIMEYMENLG

DLKSYILKNP-------------------TIQTSQCISICTQLAAGLAYLESCNFVHRDIAARNCLVDGEGNVKIADFG--MARSLYSQEYYKVEG----
||........                   ||....|..||||.|.|..||||.||||||.|.|||||..|...||.|||  |.|.||||.||.|||    
DLNQFWMEHEAENSGLMNCKADTQNCQKPTISYECCVYICTQIASGMKYLESMNFVHRDLATRNCLVGKEYHIKICDFGTVMSRNLYSQDYYRVEGFTGR

-KFVLPIRWMAWEALLLGKFSTASDVWGFGVTMWEIFSLCSEKPYSDMTDDDVVENLQSMSSTGSLKQVLSRPRMCPSKLYNEQILPCWNYESSRRPSFE
 ....||||||||..|||||.|.||||.|||||||.|..|.|.||...||..|.||.............|..|.|||...||.....||....|.|||||
QRHHMPIRWMAWESILLGKFTTKSDVWAFGVTMWEMFMFCREQPYEQLTDEQVIENACEFFRHQGMQVYLPMPPMCPYEIYNQLMCRCWRRDQSQRPSFE

NVHLHL
..|..|
EIHKFL
Kinase F11D5.3.AA TyrKc 527-785 37 9.5e-118 398.4 SMART 1-280 (280) Show / Hide 
Range on Protein: 527-785
Range on HMM: 1-280/280
Sequence Identity: 37% (107 aa)

LICVSRIGQGEFGEVDLCQLENRKVAVKKLHGISQADEFSFHREIRVLGSL--KHPNVVEVVGVCTIQ-------KPILCIMEYMENGDLKSYILKNPT-
.     .| |.|||| ....  ..||||.|.  .   .  |.||.|.. .|  .|||.|  .|||| |       .|.. .||||..||||.|. |.   
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

IQTSQCISICTQLAAGLAYLESCNFVHRDIAARNCLVDGEGNVKIADFGMARSLYSQ-------EYYKV----EGKFVLPIRWMAWEALLLGKFSTASDV
..... .|.|.| |.| .||.| |..|||.|||||||. .. |||.|||..| .|.        .||..     ||..|||||||.|..  |||.|.|||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WGFGVTMWEIFSLCSEKPYSD-----MTDDDVVENLQSMSSTGSLKQVLSRPRM----CPSKLYNEQILPCWNYESSRRPSFENVHLHL
| |||.|||||... ..||..     |....|.|....       . ..  | |    ||...|.  .. ||... . ||.|...|  .
WSFGVCMWEIFTYG-QQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase F11D5.3.AA TK 527-785 23 3.7e-105 353.56 In-house 1-486 (486) Show / Hide 
Range on Protein: 527-785
Range on HMM: 1-486/486
Sequence Identity: 23% (114 aa)

LICVSRIGQGEFG---EVDLCQLENR---------------------------KVAVKKLH---GISQADEFS--------------FHREIRVLGS--L
.. .  .|.|.||   || ......|                           .|||| |.   . ||...|               . .|. .. .  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

KHPNVVEVVGVCTIQ------------KPILCIMEYMENGD----LKSYILKNP----------------------------------------------
.|||.|  .|||| .            .|....||||..||    |..|  |..                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------TIQTSQCIS-------------------ICTQLAAGLAYLESC------NFVHRDIAARNCLVDGEGN-----------VKIADFG----
          ...|.. ..                   .| |.|.|..||.|.      ||||||.|||||||. ...           .||||||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----MARSLYS------------------------QEYYKVEGKFVLPIRWMAWEALL---------LGKFSTASDVWGFGVTMWEIFSLCSEKPYSDMT
    .|| .||                        |.||. . .  |||||||.|.|.          |||.|.|||| |||.|||||... | .| .|.
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

D---------DDVVENLQSMS----STGSL-----KQVLSRPRMCPS-------------KLYNEQILPCWNYESSRRPSFENVHLHL
.         ..|.|.|.. .    | | |     .  . .|  ||.             ..| . .. ||.|. ..||.|. .|  |
NQDVWKDGDNQEVMEYLRRGGRLCRS-G-LNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase F11D5.3.AA Pkinase_Tyr 527-785 37 1.2e-103 351.6 Pfam 1-270 (270) Show / Hide 
Range on Protein: 527-785
Range on HMM: 1-270/270
Sequence Identity: 37% (105 aa)

LICVSRIGQGEFGEVDLCQLE------NRKVAVKKLHGISQADE---FSFHREIRVLGSL-KHPNVVEVVGVCT-IQKP--ILCIMEYMENGDLKSYILK
..    .|.|.|||| .. .       . .||||.|   .  ..    .| ||.... .| .|||.|  .||||  ..|  |. .||||..|||..|  |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----NPTIQTSQCISICTQLAAGLAYLESCNFVHRDIAARNCLVDGEGNVKIADFGMARSLYSQEYY-KVEGKFVLPIRWMAWEALLLGKFSTASDVWGF
    .. . ... ...|.| |.|..|||| |..|||.|||||||. .. |||.|||.|| .|. .|| .. |.  |||.||| |..  |||.|.|||| |
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GVTMWEIFSLCSEKP-YSDMTDDDVVENL-QSMSSTGSLKQVLSRPRMCPSKLYNEQILPCWNYESSRRPSFENVHLHL
||.|||||...  .| | .|.. .|.| . ..        . . .|. || ..|.  .. ||.|. ..||.|. .| .|
GVLMWEIFTYGE-QPTYPGMSNEEVYEYIYED-------GYRMPCPENCPDEIYDL-MKQCWHYDPEDRPTFSEIHEQL
Kinase F11D5.3.AA UTK 527-785 32 2.6e-74 253.17 In-house 1-296 (296) Show / Hide 
Range on Protein: 527-785
Range on HMM: 1-296/296
Sequence Identity: 32% (99 aa)

LICVSRIGQGEFGEVDLCQLEN-------RKVAVKKLHGISQADEFS------FHREIR---VLGSLK-HPNVVEVVGVCTIQKPILCIMEYMENGDLKS
..   ..|||.|||| .. ...        .||||..   . .....      | .| |   ... .. ||||. .||||| ..|.. ..|||||||| |
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ-HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRS

YILKNPT-------IQTSQC-ISICTQLAAGLAYLESCNFVHRDIAARNCLVDGEG-------NVKIADFG---MARSLY---------SQEYYKVEGKF
|  ...        ..|. . .. . . |.|..||.||.|||||.|||||||.  .        .||||||   |.| ..         ...||.  .  
YLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQD

VLPIRWMAWEALLLG-KFSTASDVWGFGVTMWEIFSLCSEKPYSDMTDDDVVENLQSMSSTGSLKQVLSRPRMCPSKLYNEQILPCWNYESSRRPSFENV
 .|||||| |||  . .|.|.|||| |||..|||..    .|| .|....|....   .      . . .|. ||  .|.   . ||.|. ..||.|| .
RWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTW-GRLPYPGMSNMQVWHQVCNGGR-----YRMPCPWDCPHPVYR-LMHRCWHYDPQERPDFEDL

HLHL
   .
VQQM
Kinase F11D5.3.AA TK-Unique 527-785 32 1.7e-68 233.85 In-house 1-294 (294) Show / Hide 
Range on Protein: 527-785
Range on HMM: 1-294/294
Sequence Identity: 32% (97 aa)

LICVSRIGQGEFGEVDLCQLEN--------RKVAVKKLH-GISQADEFSFHREIRVLGSLK-HPNVVEVVGVCT-IQKPILCIMEYMENGDLKSYILKNP
|   ..||.|.||.|  .....        ..||||.|. . .. |.  | .||... .|. |||.|  .|.||  . | . ||||...|.| .|. .. 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

T--------------------------IQTSQCISICTQLAAGLAYLES--CNFVHRDIAARNCLVDGEGNVKIADFGMARSLYSQEYYKVEGK-FVLPI
                           |.  . .... |.| |..||.|  ...||||..|||.|. . ...||.|||||| .|  . |  ... . .||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWMAWEALL--LGKF-STASDVWGFGVTMWEIFSLCSEKPYSDMTDDDVVENLQSMSSTGSLKQVLSRPRMC-PSKLYNEQILPCWNYESSRRPSFENVH
|||| |.|.   | . .| |||| |||.|||||.| .  ||..| ..|..|... ..        . .|  | .  .||  .  ||..| . ||||. . 
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGA-CPYPGMPWKDIMECIRDGY-------RMPQPEHCCSHEMYNLMKS-CWQWEPEERPSFRQIK

LHL
  |
HRL
Kinase F11D5.3.AA Trk 527-785 35 1.5e-67 228.06 In-house 1-275 (275) Show / Hide 
Range on Protein: 527-785
Range on HMM: 1-275/275
Sequence Identity: 35% (100 aa)

LICVSRIGQGEFGEVDLCQLENRK-------VAVKKLHGISQADEFSFHREIRVLGSLKHPNVVEVVGVCTIQKPILCIMEYMENGDLKSY---------
..    .| | || | | . .|         |||| |   |..    |.|| ..|  |.|...|   |||| ..|.| . |||..|||. |         
IVLKWELGEGAFGKVFLAECYNLCPEQDKMMVAVKTLKDASENARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPDAM

-ILKNPT------IQTSQCISICTQLAAGLAYLESCNFVHRDIAARNCLVDGEGNVKIADFGMARSLYS-QEYYKVEGKFVLPIRWMAWEALLLGKFSTA
 .....          .|   |  | |.|. |. |  |||||.|.||||| ..  |||.|||| | .||  .||.|...  ||||||  |. .  ||.. 
CYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESIMYRKFTYE

SDVWGFGVTMWEIFSLCSEKPYSDMTDDDVVENLQSMSSTGSLKQVLSRPRMCPSKLYNEQILPCWNYESSRRPSFENVHLHL
|||| |||.|||.|.     |.  .    |.|           .. | ||| ||  .| .  | ||  |  .| .  ..|  .
SDVWSFGVVMWECFTYG-KQPWYQLSNHEVIECIHQG------RHRLERPRRCPQEVY-DIMLGCWQREPQQRMNIKDIHDII
Kinase F11D5.3.AA Src 527-785 34 3.9e-66 223.66 In-house 1-255 (255) Show / Hide 
Range on Protein: 527-785
Range on HMM: 1-255/255
Sequence Identity: 34% (93 aa)

LICVSRIGQGEFGEVDLCQLEN-RKVAVKKLHGISQADEFSFHREIRVLGSLKHPNVVEVVGVCTIQKPILCIMEYMENGDLKSYIL---KNPTIQTSQC
.  . ..||| ||||      .  ||||| |   .  .   | .|. .. .|.|...|.   ||.  .||. . |||..| |  |     .  ...  | 
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGT-MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQL

ISICTQLAAGLAYLESCNFVHRDIAARNCLVDGEGNVKIADFGMARSLY--SQEY-YKVEGKFVLPIRWMAWEALLLGKFSTASDVWGFGVTMWEIFSLC
|.. .| |.| ||||| |..||| |||| ||. .  .|.|||| || .     ||  . . ||  ||.|.| ||.. |.|.. |||| ||. ..||..  
IDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKF--PIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYG

SEKPYSDMTDDDVVENLQSMSSTGSLKQVLSRPRMCPSKLYNEQILPCWNYESSRRPSFENVHLHL
   ||  ||  .|....       .    . .|. || .||.. .| ||. .  .|| ||  .  |
-RVPYPGMTNHEVLQQV-------ERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase F11D5.3.AA Frk 527-789 36 9.9e-62 211.4 In-house 1-260 (260) Show / Hide 
Range on Protein: 527-789
Range on HMM: 1-260/260
Sequence Identity: 36% (98 aa)

LICVSRIGQGEFGEVDLCQLENRK-VAVKKLHGISQADEFSFHREIRVLGSLKHPNVVEVVGVCTIQKPILCIMEYMENGDLKSYIL----KNPTIQTSQ
.  . |.| | ||||   . .|   ||||.|   . .|   | || ... .|.|| ....  |||...||. | | |..| |. |.     |   .|  |
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGT-MDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQ

CISICTQLAAGLAYLESCNFVHRDIAARNCLVDGEGNVKIADFGMARSLYSQEY--YKVEGKFVLPIRWMAWEALLLGKFSTASDVWGFGVTMWEIFSLC
 . .  |.|||.||||| |..|||.|||| ||. .  .||||||.|| |  ..   |       .||.| | ||    ||.. |||| ||. . ||    
LVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYG

SEKPYSDMTDDDVVENLQSMSSTGSLKQVLSRPRMCPSKLYNEQILPCWNYESSRRPSFENVHLHLQSLV
   ||. ||. .|.. ..           . .|  || .|| | .| ||. .. .|| || ..  |.   
-RMPYPGMTNAEVLQMVDHG-------YRMPQPPNCPQQLY-EIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase F11D5.3.AA Musk 625-785 40 4.8e-54 176.86 In-house 131-282 (282) Show / Hide 
Range on Protein: 625-785
Range on HMM: 131-282/282
Sequence Identity: 40% (65 aa)

ICTQLAAGLAYLESCNFVHRDIAARNCLVDGEGNVKIADFGMARSLYSQEYYKVEGKFVLPIRWMAWEALLLGKFSTASDVWGFGVTMWEIFSLCSEKPY
.  | |.|.|||    |||||.| ||||.  .  |||||||..|  |.|.||| ..    |||||. |...  .|...|||| .|| .|||||   . ||
MAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPESIWYNQFTYESDVWAYGVCLWEIFSYA-LQPY

SDMTDDDVVENLQSMSSTGSLKQVLSRPRMCPSKLYNEQILPCWNYESSRRPSFENVHLHL
  ||  .|.   .          .|| |  || |.|.     ||. . . ||.| ..|  .
YGMTHEEVIYYIRQG-------NILSCPENCPQKVYQ-LMRRCWQKNPADRPFFCQIHHCI
Kinase F11D5.3.AA CTKA 628-785 48 6.9e-48 158.91 In-house 139-290 (290) Show / Hide 
Range on Protein: 628-785
Range on HMM: 139-290/290
Sequence Identity: 48% (77 aa)

QLAAGLAYLESCNFVHRDIAARNCLVDGEGN-VKIADFGMARSLYSQ-EYYKVEGKFVLPIRWMAWEALLLGKFSTASDVWGFGVTMWEIFSLCSEKPYS
| |||  || .  ||||| |.||||. | .. .|||||| .| | .   || |  . |.|.|||| |||  ||||.||||| ||| .|||.|   |||. 
QIAAGMNYLAEMGFVHRDLACRNCLL-GQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMG-EKPWR

DMTDDDVVENLQSMSSTGSLKQVLSRPRMCPSKLYNEQILPCWNYESSRRPSFENVHLHL
 |.|  |.   | . | |   . |  || ||. ||      ||  |   ||.|| .   |
HMSDQEVC---QAYTSHG--MRRLPVPRNCPQVLY-HCMQECWKFEPNQRPTFETLQRML
Kinase F11D5.3.AA Ror 625-717 56 2.4e-47 163.64 In-house 124-216 (308) Show / Hide 
Range on Protein: 625-717
Range on HMM: 124-216/308
Sequence Identity: 56% (53 aa)

ICTQLAAGLAYLESCNFVHRDIAARNCLVDGEGNVKIADFGMARSLYSQEYYKVEGKFVLPIRWMAWEALLLGKFSTASDVWGFGVTMWEIFS
| .| |||  || |  ||||| |||||||  . .|||.||| .|  ||  ||.. .| ..|||||. || . ||||..||.| |||. |||.|
IAIQIAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGLMRDIYSSDYYRMQHKSWMPIRWMSPEAIMYGKFSEDSDIWSFGVVLWEIWS
Kinase F11D5.3.AA S_TKc 527-787 22 2.9e-43 150.97 SMART 1-231 (231) Show / Hide 
Range on Protein: 527-787
Range on HMM: 1-231/231
Sequence Identity: 22% (63 aa)

LICVSRIGQGEFGEVDLCQLEN--RKVAVKKLHGISQADEFSFHREIRVLGSLKHPNVVEVVGVCTIQKPILCIMEYMEN--GDLKSYILKNPT------
   .  ||.| ||.| .|.  .  |.||.|...        .. |||..| . .|||.|   .|.   . .  .|||...  |||..|| |...      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

IQTSQCISICTQLAAGLAYLESCNFVHRDIAARNCLVDGEGNVKIADFGMARSLYSQEYYKVEGKFVLPIRWMAWEALLLGKFST-ASDVWGFGVTMWEI
.   .. ... |.. .|.|. | ...|||.   | |.|   ..||.|||.|| |           |.    .|| | |   .... ..|.| .|....| 
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

FSLCSEKPYSDMTDDDVVENLQSMSSTGSLKQVLSRPRMCPSKLYNEQILPCWNYESSRRPSFENVHL-------HLQS
.. .   |..  ... . ...                    |.   . |  |.... ..||.   .         |   
LCGYP--PFP--QMQMMFKKIG-------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase F11D5.3.AA Pkinase 527-717 25 1.7e-37 133.62 Pfam 1-207 (293) Show / Hide 
Range on Protein: 527-717
Range on HMM: 1-207/293
Sequence Identity: 25% (55 aa)

LICVSRIGQGEFGEVDLCQLENRK--VAVKKLHGISQADEF---SFH-REIRVLGSLKHPNVVEVVGVCTIQKPILCIMEYMENG----DLKSYIL--KN
. ....||.| ||.| .|.  .    ||||..   .. ...    .. .||... .|.|||.|.  ....  . |  .|||.|.|    ||..||   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PTI--QTSQCISICTQLAAGLAYLESCNFVHRDIAARNCLVDGEGNV----KIADFGMARS--LYSQEYYKVEGKFVLPIRWMAWEALL-LGKFSTASDV
 ..  .  .|.....|.. ||.|. |....|||.   |.|.| .|..    ||.||| |.   . ... ...   |.  ...|| | ..   . ....|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTT---FCGTPWYMAPEVIRGGQYYGPKVDM

WGFGVTMWEIFS
|..|....| ..
WSCGCILYEMLC
Kinase F11D5.3.AA CTKA 527-611 33 6.9e-16 49.74 In-house 1-100 (290) Show / Hide 
Range on Protein: 527-611
Range on HMM: 1-100/290
Sequence Identity: 33% (33 aa)

LICVSRIGQGEFGEVDLCQLENR------------KVAVKKLHGISQADEF-SFHREIRVLG--SLKHPNVVEVVGVCTIQKPILCIMEYMENGDLKSYI
.   ..|| | .|.|    |  .             |||| |       .   |  | .||    . ||||.  .||||  || . |||.|  |||..|.
HCIMFKIGEGHYGQVFRAWLMPDPDDFKAQRKKGKDVAVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGDLHCYL
Kinase F11D5.3.AA Ror 551-607 43 3.2e-12 45.06 In-house 32-89 (308) Show / Hide 
Range on Protein: 551-607
Range on HMM: 32-89/308
Sequence Identity: 43% (25 aa)

VAVKKL-HGISQADEFSFHREIRVLGSLKHPNVVEVVGVCTIQKPILCIMEYMENGDL
||.|.. |  | |    | .||..  .|.|||.|   ||||  .| . . ||| .|||
VAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMDQPYCMLFEYMNHGDL
Kinase F11D5.3.AA Musk 527-610 33 1.8e-10 30.61 In-house 1-92 (282) Show / Hide 
Range on Protein: 527-610
Range on HMM: 1-92/282
Sequence Identity: 33% (31 aa)

LICVSRIGQGEFGEVD-------LCQLENRKVAVKKLHGISQAD-EFSFHREIRVLGSLKHPNVVEVVGVCTIQKPILCIMEYMENGDLKSY
 | |  ||.| || |        . . |.  |||| |     ..    | ||   .    |||.|   ||| . .|.   .|||  |||  .
IIYVRDIGEGAFGRVFQARAPGLVPYEEETMVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDLNEF
Kinase F11D5.3.AA Ror 767-794 42 0.016849 6.3 In-house 257-284 (308) Show / Hide 
Range on Protein: 767-794
Range on HMM: 257-284/308
Sequence Identity: 42% (12 aa)

CWNYESSRRPSFENVHLHLQSLVHTSPH
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CWHEIPSRRPRFKDIHSRLRSWDNLSNH