Gene F18F11.4 (Nematode worm)
F18F11.4
Group:
Other
Family:
Other-Unique
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| F18F11.4.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 232 | Kinase domain by global Sugen HMM | Fasta, JSON |
| F18F11.4.AA | Protein | Genbank | 959 | None | Fasta, JSON |
Protein domains of F18F11.4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | F18F11.4.AA | Other-Unique | 15-235 | 12 | 7.7e-28 | 91.73 | In-house | 1-249 (249) | Show / Hide |
Range on Protein: 15-235 Range on HMM: 1-249/249 Sequence Identity: 12% (31 aa) NTPDEIEKISRTIEDLCQLRHKRLAPMYGYHWRLETELMVFR----------------------------AHVPSGTVADLVKVS-----AIPQETAVRY . ... . .|... ......| .| . .|. . | .. |.|........... .. |.. ... IKDIGKGTYGRVYKQHHNKKKKYCAKKTKHHKI-HCMDMDNNKREQIYHYQIIHCIFYWTMNHCHLCFCYEHCPNMIFYIMYPWYHHHCECQCQCEHWMN IVHVIDALAYLHERKHVHGKLNASNLLLTISNDILLADPFIEG---LPSAQKRRALLASPPEAFRSLESYPCLTPSSDIWSVGCVLVTMLTRYPPFLEHY ..|.| .| .||...|.|...|..|..... |.. ... .... . ..... .. . .. . .....|.. ... .. .... .. . .. . .. CCHMIHNLHHLHNNNHIHCDINPNNIWINQNNIHMCHNCGHNIPTII-IEHQHIKIMDFNNN-N-MMYFAPEF-SCRWCSPETFDYWPLGEKIDQYHFGC MHFHGESLHRELVSEWCTRRQLIYSSQTLIPSASKEICELIDQIFNVDPENRPSAQN .||| ...|... .... ... .. |. | . . ..||...|.. |.|...|.... YHFHMNCQHWIFHYHDV-QHWPPHESPKDI-HILICQCECCHQCM-VNPYQNPNCFY |
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| Kinase | F18F11.4.AA | Pkinase | 152-239 | 25 | 2.3e-12 | 44.83 | Pfam | 190-290 (293) | Show / Hide |
Range on Protein: 152-239 Range on HMM: 190-290/293 Sequence Identity: 25% (26 aa) TPSSDIWSVGCVLVTMLTRYPPFLEH---------YMHFHGES-LHRELVSEWCTRR------QLIYSSQTLIPSASKEICELIDQIFNVDPENRPSAQN .|..|.||.||.| ||...||| .| .|.. . .. ..||... . .|. . .|.| ...|. ....||. ||.|. GPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHW-HF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQ LLES .|.. ILQH |
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| S_TKc | F18F11.4.AA | S_TKc | 4-243 | 19 | 3e-11 | -11.86 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 4-243 Range on HMM: 1-231/231 Sequence Identity: 19% (54 aa) YTVTE----------WKLKEGNTPDEI------EKISRTIEDLCQLRHKRLAPMYGYHWRLETELMVFRAHVPS--GTVADLVKVSA-------IPQETA |.. . .| .. .| . |.| | |. | . .|. . .|.. ..| .. ... |.. |. | .| .| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HA VRYIVHVIDALAYLHERKHVHGKLNASNLLLTISNDILLAD-----PFIEGLPSAQKRRALLASP----PEAFRSLESYPCLTPSSDIWSVGCVLVTMLT .|. ...||.|.|... .| | .|.||. | ..| . . . .| || . . ....|.||.||.| ||. RFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCILYEMLC RYPPFLEHYMHFHGESLHRELVSEWCTRRQLIYSSQTLIPSASKEICELIDQIFNVDPENRPSAQNLLE------SHGSK .|||| . . . . .. |.| ...|......|||.||.| .|. .| GYPPFP------QMQMMFKKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | F18F11.4.AA | Ciliate-E2 | 152-242 | 20 | 1e-09 | 29.49 | In-house | 274-365 (365) | Show / Hide |
Range on Protein: 152-242 Range on HMM: 274-365/365 Sequence Identity: 20% (23 aa) TPSSDIWSVGCVLVTMLTRYPPFLEHYMHFHGESLHRELVSEWCTRRQLIYSSQTLIPSA-------------------SKEICELIDQ----IFNVDPE . ..||||.|..| ||. .||| | | . .|.. |.| || . ....||| DYKCDIWSLGVILYEMLFGKPPF-----------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPE NRPS-AQNLLESHGS .|.. .. .|. . KRITGWEQILNHPWF |
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| Kinase | F18F11.4.AA | NEK1 | 212-242 | 35 | 1.9e-08 | 25.6 | In-house | 246-276 (276) | Show / Hide |
Range on Protein: 212-242 Range on HMM: 246-276/276 Sequence Identity: 35% (11 aa) SKEICELIDQIFNVDPENRPSAQNLLESHGS |.|. .|. | |...|..|||.. .||.. SYELQSLVSQMFKRNPRHRPSVNQILERPFI |
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| Kinase | F18F11.4.AA | SLK | 27-119 | 27 | 1.2e-07 | 21.8 | In-house | 47-140 (259) | Show / Hide |
Range on Protein: 27-119 Range on HMM: 47-140/259 Sequence Identity: 27% (26 aa) IEDLCQLRHKRLAPMYGYHWRLETELMVFRAHVPSGTVAD-LVKVSAIPQETAVRYIV-HVIDALAYLHERKHVHGKLNASNLLLTISNDILLAD |. | .. | . .|. .. . .|... . . | | .| . .| ..|. |...|| .||..| .| | | |.|.|. |. ||| IDILSECKHPNIVKLYEAYY-YDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLAD |
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| Kinase | F18F11.4.AA | RAD53 | 152-178 | 48 | 7.5e-07 | 15.88 | In-house | 219-245 (305) | Show / Hide |
Range on Protein: 152-178 Range on HMM: 219-245/305 Sequence Identity: 48% (13 aa) TPSSDIWSVGCVLVTMLTRYPPFLEHY |.. |.|| ||.| ..|. |||| ..| TKKVDCWSMGCILYICLCGYPPFSDDY |
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| Kinase | F18F11.4.AA | CAMK | 149-174 | 50 | 7.8e-07 | 17.28 | In-house | 309-334 (425) | Show / Hide |
Range on Protein: 149-174 Range on HMM: 309-334/425 Sequence Identity: 50% (13 aa) PCLTPSSDIWSVGCVLVTMLTRYPPF | .|..|.||.|..| .||. |||| PYYGPKCDMWSCGVILYIMLCGYPPF |
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| Kinase | F18F11.4.AA | STE | 10-119 | 16 | 1e-06 | 19.57 | In-house | 48-190 (359) | Show / Hide |
Range on Protein: 10-119 Range on HMM: 48-190/359 Sequence Identity: 16% (24 aa) KLKEGNT--------------PDEIEKISRTIEDLCQLR--HKRLAPMYGYHWRL------ETELMVFRAHVPSGTVADLVK-V--------------SA .|.. |. ..|...| . |. . ... |. ||.. . ..|| .. ... |.. |..| . . NLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHR IPQETAVRYIVHVIDA-LAYLHERKHVHGKLNASNLLLTISNDILLAD .| . .... .. . |.|||. . .| . ..| || . |.| FPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCD |
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| Kinase | F18F11.4.AA | ASK | 153-176 | 54 | 1.6e-05 | 14.11 | In-house | 176-199 (254) | Show / Hide |
Range on Protein: 153-176 Range on HMM: 176-199/254 Sequence Identity: 54% (13 aa) PSSDIWSVGCVLVTMLTRYPPFLE .. ||||.|| .| | | ||| | KPADIWSFGCTMVEMATGKPPFHE |
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| Kinase | F18F11.4.AA | STE | 154-179 | 44 | 2.3e-05 | 15.02 | In-house | 248-274 (359) | Show / Hide |
Range on Protein: 154-179 Range on HMM: 248-274/359 Sequence Identity: 44% (12 aa) SSDIWSVGCVLVTMLTRYPPFLE-HYM ..||||.||... |.| ||. . |.| KCDIWSLGCTIIEMATGKPPWHDMHPM |
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| TyrKc | F18F11.4.AA | TyrKc | 4-240 | 16 | 3.9e-05 | -139.66 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 4-240 Range on HMM: 1-280/280 Sequence Identity: 16% (47 aa) YTVTEW---------------------KLKEGNTPDEIEKISRTIEDLCQL--RHKRLAPMYGYHWRLE-------TELMVFRAHVPSGTVADLVKVSA- | . .|||. .| . | .. .|.| .|. . .||. . . ||. ..| | | . . ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGV-CTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP -IPQETAVRYIVHVIDALAYLHERKHVHGKLNASNLLLTISNDILLADP----FIEGL------PSAQK------RRALLA---SPPEAFRSLESYPCLT .. .. . . . . . .|||... .| | | | |.. . . .| .|. . . ....| .||.. | . | KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----NYGKFT PSSDIWSVGCVL--VTMLTRYPPFLEHYMHFHGESLHRELVSE-WCTRRQLIY--SSQTLIPSASKEICELIDQIFNVDPENRPSAQNLLESH . ||.|| | .. . . |. . . . ... . . . . .| |. . ...|. ... | . |||.||. ... | TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF----VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | F18F11.4.AA | STE | 212-240 | 40 | 4.2e-05 | 14.09 | In-house | 327-356 (359) | Show / Hide |
Range on Protein: 212-240 Range on HMM: 327-356/359 Sequence Identity: 40% (12 aa) SKEICELIDQIFNVDPENRPSAQNLLES-H |.| .. |.. .. ||..||.|. ||.| | SPEFKDFINKCLQKDPNKRPTASQLLKSEH |
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| Kinase | F18F11.4.AA | Ciliate-E2-Unclassified | 154-174 | 52 | 6.6e-05 | 12.97 | In-house | 250-270 (352) | Show / Hide |
Range on Protein: 154-174 Range on HMM: 250-270/352 Sequence Identity: 52% (11 aa) SSDIWSVGCVLVTMLTRYPPF ..||||.|..| ||. |.|| KCDIWSLGVILYEMLFGYYPF |
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| Kinase | F18F11.4.AA | MEKK2 | 156-177 | 54 | 8.1e-05 | 13.4 | In-house | 188-209 (262) | Show / Hide |
Range on Protein: 156-177 Range on HMM: 188-209/262 Sequence Identity: 54% (12 aa) DIWSVGCVLVTMLTRYPPFLEH |.||.|| | ||| ||. |. DVWSIGCTVVEMLTEKPPWAEY |
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| Kinase | F18F11.4.AA | MEKK2 | 15-119 | 28 | 0.00015 | 12.41 | In-house | 40-146 (262) | Show / Hide |
Range on Protein: 15-119 Range on HMM: 40-146/262 Sequence Identity: 28% (31 aa) NTPDEIEKISRTIEDLCQLRHKRLAPMYG-YHWRLETELMVFRAHVPSGTVADLVKVSAIPQETAVR-YIVHVIDALAYLHERKHVHGKLNASNLLLTIS .| |.. . |. | |.|.|. || . . | | .| ..| | | | .|. || | | ... ..|||. || . |.| | ETRKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQLKAYGALTETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDSS NDILLAD . |.| GNVKLGD |
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| Kinase | F18F11.4.AA | CAMK | 78-119 | 25 | 0.000269 | 8.96 | In-house | 181-239 (425) | Show / Hide |
Range on Protein: 78-119 Range on HMM: 181-239/425 Sequence Identity: 25% (15 aa) AVRYIVHVIDALAYLHERKHVHGKLNASNLLLTIS-----------------NDILLAD | ||. ...|..|.|... || | |.||. . |.| ..| ARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIID |
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| Kinase | F18F11.4.AA | CAMK | 212-238 | 37 | 0.000724 | 7.55 | In-house | 395-421 (425) | Show / Hide |
Range on Protein: 212-238 Range on HMM: 395-421/425 Sequence Identity: 37% (10 aa) SKEICELIDQIFNVDPENRPSAQNLLE |.| || .. .||||.|.... |. SQECKDLIRKMLQVDPEKRMTIEQCLN |
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| Kinase | F18F11.4.AA | RAD53 | 218-237 | 40 | 0.000865 | 6.59 | In-house | 281-300 (305) | Show / Hide |
Range on Protein: 218-237 Range on HMM: 281-300/305 Sequence Identity: 40% (8 aa) LIDQIFNVDPENRPSAQNLL ||.. .||||.|... ..| LIKWMLCVDPEKRYTIDEAL |
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| Kinase | F18F11.4.AA | Ciliate-E2-Unclassified | 73-119 | 19 | 0.002093 | 7.7 | In-house | 135-190 (352) | Show / Hide |
Range on Protein: 73-119 Range on HMM: 135-190/352 Sequence Identity: 19% (11 aa) IPQETAV-----RYIVHVIDALAYLHERKHV-HGKLNASNLLLTISN---DILLAD .. . |. .|. .....| |||. ... | . .|.|.. .. | ..| FTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIID |
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| Kinase | F18F11.4.AA | ASK | 212-242 | 38 | 0.005994 | 5.43 | In-house | 224-254 (254) | Show / Hide |
Range on Protein: 212-242 Range on HMM: 224-254/254 Sequence Identity: 38% (12 aa) SKEICELIDQIFNVDPENRPSAQNLLESHGS |.| . | . |..||..|.|||.||. SAECKNFILRCFEPDPCKRASAQDLLQDPFL |
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| Kinase | F18F11.4.AA | ASK | 52-109 | 27 | 0.006964 | 5.21 | In-house | 66-127 (254) | Show / Hide |
Range on Protein: 52-109 Range on HMM: 66-127/254 Sequence Identity: 27% (17 aa) LMVFRAHVPSGTVADLVKVSAIPQE----TAVRYIVHVIDALAYLHERKHVHGKLNASNLLL . .| .|| | ...|.. | . | | ... | ||||.. || . | |. FKIFMEQVPGGSLSALLRSKWGPMKDNENTMNFYTKQILEGLKYLHENQIVHRDIKGDNVLV |
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| Kinase | F18F11.4.AA | Ciliate-E2 | 81-119 | 32 | 0.007402 | 5.62 | In-house | 165-199 (365) | Show / Hide |
Range on Protein: 81-119 Range on HMM: 165-199/365 Sequence Identity: 32% (13 aa) YIVHVIDALAYLHERK-HVHGKLNASNLLLTISNDILLAD ||. .|.|| |||... .| . .|.|. | ..| YIACIILALEYLHSKNNIIHRDIKPENILF-----IKIID |
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| Kinase | F18F11.4.AA | NEK1 | 155-164 | 90 | 0.023983 | 4.15 | In-house | 202-211 (276) | Show / Hide |
Range on Protein: 155-164 Range on HMM: 202-211/276 Sequence Identity: 90% (9 aa) SDIWSVGCVL ||||| |||| SDIWSLGCVL |
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| Kinase | F18F11.4.AA | Ciliate-E2-Unclassified | 213-238 | 18 | 0.030432 | 3.61 | In-house | 322-348 (352) | Show / Hide |
Range on Protein: 213-238 Range on HMM: 322-348/352 Sequence Identity: 18% (5 aa) KEICE-LIDQIFNVDPENRPSAQNLLE |.... |. ......|..|.... .|. KDFINDLLQKMLKKNPNKRITFEQILN |
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| DUF23 | F18F11.4.AA | DUF23 | 620-903 | 17 | 2.2e-41 | 148.6 | Pfam | 1-335 (335) | Show / Hide |
Range on Protein: 620-903 Range on HMM: 1-335/335 Sequence Identity: 17% (61 aa) HTLGVCLQPIFF-FTDWTVIIQFFESWIAQ--GATKFYFYLHSYTWQTKKVLNFYKQSLGDDLELLDWS-----D------LPFNSKSIAI--------- | ..||..|... ...|. .. ..| | .| |||.|.||.|| |....|||..| .. ....|. | . . .||. HPVVVCVCPMYWNEPKWLQWQEWIEHWHWQKRGATHFHFYIHSMTEYYYKVLKHYEKT-DGYVEIHPWPMRMKFPWPDMPYHDWNSNVEWHNQMAAHNDC -LPSRSKVKFVANTDLDDLAVSSS-----LNISDALNKASDRHPNAAQFKVDWILSHQPQHWDSIHTPRDVNFGLQSVRVLEID------------SIRY | .. .|..|. |.|.. . . ...| |.. | . .| .|...|...|. ... .||. .| . ..|. | ...| HLRYKYAAKWIAFFDIDERLMPRNYPTYFQEFNDYLQNHPDISYGAYHFRNHWVMKHSFMPSFYENSPRWMFFNWWCCRTRETQMEQWMMFHKWHNTKHY DYRVSK------KMFHRPERVVHFDMHSVYRNELSEDKTHQHTTIEIYDSLNLYYLHLRRFE------RHLLNPPVVKYNNRFNSSLLMKLNTKMLDQFT .. .| |...|||.|.. .|.. .. ...| | .. .... . . .|. ... |. .. ..|... . . .....|.... GCPWHKNQWCRHKCIVRPEKVNSMWIHWPWHFYNKTMYT-Q-LYH-RHNIEGYHITHVKKPIWFFRHYRDQHDHEPKHYWPMNYYDNTQIIREKDIKMID ERMEGTEFGEAMLSPWALDA--HQTMRDLEQCRREAFGT |... ... .|. . | ..... .|. . | . EDFWRMWNWQNIWKHWFELPMEHYYFWIIWKCYNCKFYH |
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