Gene F46F2.2 (Nematode worm)

F46F2.2

Species: Nematode worm
Alias: aSWK074, F46F2.2, CE05879, YWRJ_CAEEL
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: X:21.05, WormBase Physical Map location: X: 15277482-15272851,

Classification

Group: CK1
Family: CK1
Subfamily: CK1-D

Sequence

Name Sequence Type Origin Length Description Download
F46F2.2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 245 Kinase domain by global Sugen HMM Fasta, JSON
F46F2.2.AA Protein Genbank 578 None Fasta, JSON

Protein domain

Protein domains of F46F2.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase F46F2.2.AA CK1 188-445 70 3.7e-205 687.86 In-house 1-271 (271) Show / Hide 
Range on Protein: 188-445
Range on HMM: 1-271/271
Sequence Identity: 70% (193 aa)

FRLGRKIGSGSFGDIYLGQNIQTNEE---VAVKLECVKSKHPQLHIESRLYRIMLG------GIGIPEIRWCGQE--GDYNVMVMELLGPSLEDLFNFCQ
.|.|||||.||||||||| |. ||.|   ||.|||. ||||||||.|...|.|. |      ..||| ..|||||  ||||.|||.|||||||||||||.
YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFCN

RKFSLKTVLLLADQMLSRVEFIHCRDYIHRDIKPDNFLMGL-GKRGNLVYIIDFGLAKRYRDSK-HQHIAYRENKNLTGTARYASINTHRGIEQSRRDDI
|||||||||..||||..|.|..| ...|||||||||||||. ||... ||||||||||||||.| |||| ||||||||||||||||||| ||||||||| 
RKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDM

ESLGYVFMYFNRGTLPWQGLKAVTKRQKYELISEKKISTRVDDLCAG-YPEAFAQYLNYCRSLGFEEQPDYG
||||||.|||.||.|||||||| ||.|||| |.|||.|| |..||.| .|. ||.||||||.|.|||.||| 
ESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase F46F2.2.AA CK1-D 188-447 81 7.4e-204 683.54 In-house 1-261 (261) Show / Hide 
Range on Protein: 188-447
Range on HMM: 1-261/261
Sequence Identity: 81% (212 aa)

FRLGRKIGSGSFGDIYLGQNIQTNEEVAVKLECVKSKHPQLHIESRLYRIMLGGIGIPEIRWCGQEGDYNVMVMELLGPSLEDLFNFCQRKFSLKTVLLL
.|.|||||||||||||.|.|||||||||.||||.|.|||||||||..|..| ||||||||||||||||||||||.|||||||||||.|.|||||||||.|
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHRKFSLKTVLML

ADQMLSRVEFIHCRDYIHRDIKPDNFLMGLGKRGNLVYIIDFGLAKRYRDSK-HQHIAYRENKNLTGTARYASINTHRGIEQSRRDDIESLGYVFMYFNR
||||..|.|.||||..|||||||||||||||||||.||||||||||||||.. ||||.|||||||||||||||||||.|||||||||.||||||.|||||
ADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNR

GTLPWQGLKAVTKRQKYELISEKKISTRVDDLCAGYPEAFAQYLNYCRSLGFEEQPDYGYL
|.||||||||.||||||| |.|||.||..|.||.|||..|.||.||||.| |...||| ||
GSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase F46F2.2.AA CK1-Unclassified 188-419 63 2.8e-189 563.75 In-house 1-244 (244) Show / Hide 
Range on Protein: 188-419
Range on HMM: 1-244/244
Sequence Identity: 63% (156 aa)

FRLGRKIGSGSFGDIYLGQNIQTNEEVAVKLECVKSKHPQLHIESRLYRIMLGGI-------GIPEIRWCGQE--GDYNVMVMELLGPSLEDLFNFCQRK
.|...|||.||||.||.. |.|||||||.|||  .|||||| .| ...... .|        ||| . |||||  ||||.|||.|||||||||||.|.||
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCNRK

FSLKTVLLLADQMLSRVEFIHCRDYIHRDIKPDNFLMG-LGKRGNLVYIIDFGLAKRYR--DSKHQHIAYRENKNLTGTARYASINTHRGIEQSRRDDIE
|||||||..||||..|.|..| . .||||||||||||| |||. . ||||||||.|||.  |. ..|| |||||||||||||||||.|.||||||||| |
FSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDLE

SLGYVFMYFNRGTLPWQGLKAVTKRQKYELISEKKISTRVDDLC
|||||..|| .|.||||..|| .| .||| | |.|.|| |. ||
SLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC
Kinase F46F2.2.AA CK1-A 188-447 69 2.5e-164 552.23 In-house 1-261 (261) Show / Hide 
Range on Protein: 188-447
Range on HMM: 1-261/261
Sequence Identity: 69% (181 aa)

FRLGRKIGSGSFGDIYLGQNIQTNEEVAVKLECVKSKHPQLHIESRLYRIMLGGIGIPEIRWCGQEGDYNVMVMELLGPSLEDLFNFCQRKFSLKTVLLL
.|| |||||||||||||| ||.  ||||.|.|  | .||||  |...|||. |..|||..|| |.| |||||||.|||||||||||||.|.|..||||.|
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKRRFTMKTVLML

ADQMLSRVEFIHCRDYIHRDIKPDNFLMGLGKRGNLVYIIDFGLAKRYRDSK-HQHIAYRENKNLTGTARYASINTHRGIEQSRRDDIESLGYVFMYFNR
||||..|.|..| . .|||||||||||||.|.  | ...|||||||.||||. .||| ||| ||||||||||||| | |||||||||.||.|||.|||||
ADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNR

GTLPWQGLKAVTKRQKYELISEKKISTRVDDLCAGYPEAFAQYLNYCRSLGFEEQPDYGYL
|.|||||.|| ||.|||| |||||.|| .. || |.|  |. |.||||.|.||||||| ||
GKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase F46F2.2.AA CK1-G 188-447 56 5.9e-148 497.84 In-house 1-266 (266) Show / Hide 
Range on Protein: 188-447
Range on HMM: 1-266/266
Sequence Identity: 56% (149 aa)

FRLGRKIGSGSFGDIYLGQNIQTNEEVAVKLECVKSKHPQLHIESRLYRIMLGGI-GIPEIRWCGQEGDYNVMVMELLGPSLEDLFNFCQRKFSLKTVLL
.| |.||| |.|| ...|.|. .|| ||.|.| .||. |||| | | |.|. |   |||.. . ||.| ||.|||.||||||||||..| ||||.|||..
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFDWCDRKFSVKTVCM

LADQMLSRVEFIHCRDYIHRDIKPDNFLMGL--GKRGNLVYIIDFGLAKRYRDSK-HQHIAYRENKNLTGTARYASINTHRGIEQSRRDDIESLGYVFMY
.| ||..|.| .| .. | ||.|||||| |    |. ....|||||.|| |.| .  |||.||| | ||||||| ||||| | |||||||.|.|| .|||
VAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMFMY

FNRGTLPWQGLKAVTKRQKYELISEKKISTRVDDLCAG--YPEAFAQYLNYCRSLGFEEQPDYGYL
| || |||||||| . ...|. | ..| .| ..||| .  .|| ||.|| | |.| |.|.||| ||
FLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase F46F2.2.AA CK1 188-447 38 7.4e-140 470.92 In-house 1-339 (339) Show / Hide 
Range on Protein: 188-447
Range on HMM: 1-339/339
Sequence Identity: 38% (130 aa)

FRLGRKIGSGSFG-DIYLG-----QNIQTN-----EEVAVKLECVKSK--HPQLHIESRLYRIMLGG-------------------IGIPEIRWCGQEGD
.....|||.|.|| .||..      ....|     ||.|.|.| .||.  ||||..|...|... ||                   ...| ..|...|.|
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

--YNVMVMELLGPSLEDLFN---FCQRKFSLKTVLLLADQMLSRVEFIHCRDYIHRDIKPDNFLMGL------GKRGN--------LVYIIDFGLAK-RY
  ||.|||.||||.||||..   .|.||||.||.| .|.|||...|..| . .||||||||||.||.      ||. .         ||.||||.|. .|
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKH-HHEWNNEHRQVYMIDFGMARRKY

RDS------------KHQHIAYRE---NKNLTG-TARYASINTHRGIEQSRRDDIESLGYVFMYFNRGT--LPWQGLKAVTK-------RQKYELISEKK
||.            ..||. .||   .|...| ||||.|||.|.|.||.||||..|..|.......||  ||||..|. .|       ..||| |.|||
RDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKK

ISTRVDDLCAG-----YPEAFAQYLNYCRSLGFEEQPDYGYL
 ||... || .     .|. | ....|.||| ... ||| ..
MSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase F46F2.2.AA TTBK 188-447 35 3.9e-52 179.53 In-house 1-257 (257) Show / Hide 
Range on Protein: 188-447
Range on HMM: 1-257/257
Sequence Identity: 35% (94 aa)

FRLGRKIGSGSFGDIYLGQNIQTN-EEVAVKLECVKSKHPQLHIESRLYRIMLGGIGIPEIRWCGQEGDYNVMVMELLGPSLEDL-FNFCQRKFSLKTVL
 .  .||| | || || ....... |.||.|.| .. .   | .|    . . |   .     || . ..| |||.|.| .| ||  .  . .||| | |
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTL

LLADQMLSRVEFIHCRDYIHRDIKPDNFLMG-LGKRGNLVYIIDFGLAKRYRDSKHQHIAYRENKNLTGTARYASINTHRGIEQSRRDDIESLGYVFMYF
 |  |.|  .| ||   . |||||| || || . .. . .|..||||| .|  .. .  . ||     ||.|||||| ||  |  |.||  || |.   |
RLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEF

NRGTLPWQGLKAVTKRQKYELISEKKISTRVDDLCAGYPEAFAQYLNYCRSLGFEEQPDYGYL
  | |||  .|   | |    . | |      .|    |. | |...  .||..|..|||  .
VQGQLPWRKIKD--KDQ----VGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase F46F2.2.AA Worm6 188-447 26 8.7e-52 178.37 In-house 1-279 (279) Show / Hide 
Range on Protein: 188-447
Range on HMM: 1-279/279
Sequence Identity: 26% (75 aa)

FRLGRKIGSGSFGDIYLGQNIQTNE--EVAVKLEC--VKSKHPQLHIESRLYRIMLGGIGI-----PEIRWCGQEGD--YNVMVMELLGPSLEDLFNFC-
. ...|||.|.||..|. .. ....  ..|.|.|    ..|...| .|   . ...    .     ..|  .|. .   .| .||.|.|..|.||  .. 
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKME---CMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRP

QRKFSLKTVLLLADQMLSRVEFIHCRDYIHRDIKPDNFLMGL-----GKRGNLVYIIDFGLAK--RYRDSKHQHIAYR-ENKNLTGTARYASINTHRGIE
.||||. | | .| |.| ..|  |   .||||.|| ||  |       .    .|..|||...  .|.. . . .  | ..    || |||... |.|.|
DRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQE

QSRRDDIESLGYVFMYFNRGTLPWQGLKAVTKRQ-KYELISEKKISTRVDDLCAGYPE-AFAQYLNYCRSLGFEEQPDYGYL
|.|.||.||  |.   . .|.|||...|.    .  .. .  .. ..   .. .. |   |   . |  .. ... ||| ..
QCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase F46F2.2.AA TTBKL 188-451 27 3.1e-51 171.25 In-house 1-288 (288) Show / Hide 
Range on Protein: 188-451
Range on HMM: 1-288/288
Sequence Identity: 27% (79 aa)

FRLGRKIGSGSFGDIYLGQNIQTNEEVAVKLECVKS-KHPQ--LHIESRLYRIML--GGIGIPEIRWCGQEGDYNVMVMELLGPSLEDLFNFCQRK--FS
..  ..||.| || .|.. .... ...|.. | ...  .    ...|  .   .   | . .|.. ..|...||| |||.|.||.| || .  ..|  ||
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

LKTVLLLADQMLSRVEFIHCRDYIHRDIKPDNFLMGLGKR----GNLVYIIDFGLAKRYRDS-----------KHQHIAYRE---NKNLTGTARYASINT
  |.. .. | |  .  .|   .||||.|| |. .|. ..      .||.||||.|..|...           | .. . |.      . || ||.|.| 
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM

HRGIEQSRRDDIESLGYVFMYFNRGTLPWQGLK-AV-TKRQKYELISEKKISTRV-DDLCAGYPEAFAQYLNYCRSLGFEEQPDYGYLRNLF
|.. ||.| ||. |. |...... | |||.... .  .   | ... |.  .    |   .. |  |.    . ||| . ..|||......|
HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRD---HDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase F46F2.2.AA Pkinase 188-433 22 1.2e-39 141.33 Pfam 1-273 (293) Show / Hide 
Range on Protein: 188-433
Range on HMM: 1-273/293
Sequence Identity: 22% (63 aa)

FRLGRKIGSGSFGDIYLGQNIQTNEEVAVKLECVKSKHPQLHI------ESRLYRIMLGGIGIPEIRWCGQEGDYNVMVMELLGPSLEDLFNFC------
...||||||||||  |..... |...||||  ........ ..      | .. . .     .  ..|.   .|.  ||||...  |. ..  .      
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLY-VMDLFDYISTW

-QRKF--SLKTVLLLADQMLSRVEFIHCRDYIHRDIKPDNFLMGLGKRGNL---VYIIDFGLAKRYRDSKHQHIAYRENKNLTGTARYASINTHR-GIEQ
 ...|  | ...   . |.|. .|..| .  ||||.||.|.|.   ..|..   | |.|||||| ..     .  .. .. ..|| .|..   .| | . 
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFD-----Y-NNS-MTTFCGTPWYMAPEVIRGGQYY

SRRDDIESLGYVFMYFNRGTLPWQGL----KAVTKRQKYELISEKKISTRVDDLCAGY----------------PEAFAQYLNYC
... |. |.| .. ..  | .|..|     . ....|....| .....   . .| ..                .|.. . ...|
GPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC
Kinase F46F2.2.AA VRK 259-391 40 5.1e-28 87.17 In-house 106-240 (284) Show / Hide 
Range on Protein: 259-391
Range on HMM: 106-240/284
Sequence Identity: 40% (56 aa)

MVMELLGPSLEDLFN-FCQRKFSLKTVLLLADQMLSRVEFIHCRDYIHRDIKPDNFLMGLGKRGNLVYIIDFGLAKRYRDS-KHQHIAYRENKNLT--GT
|||. .| .|. .    .  .|| |||| || .||   |..|  .| | |||  | | |. |  . || .|.||| || .. ||   .| |..     ||
MVMPRFGRDLQKIYEDQNGHRFSMKTVLQLACRMLDVLEYLHENEYVHGDIKAANILLGFEKNPDQVYLVDYGLAYRYCPNGKHR--QYKEDPRRCHNGT

ARYASINTHRGIEQSRRDDIESLGYVFMYFNRGTLPW
  . |.  |.|   ||| |.|.|||  |.   |.|||
CEFTSMDAHKGCAPSRRSDLEILGYCMMMWLYGYLPW
Kinase F46F2.2.AA S_TKc 188-465 17 5.3e-15 43.07 SMART 1-231 (231) Show / Hide 
Range on Protein: 188-465
Range on HMM: 1-231/231
Sequence Identity: 17% (52 aa)

FRLGRKIGSGSFGDIYLGQNIQTNEEVAVKLECVKSKHPQLHIESRLYRIMLGGIGIPEIRWCGQEGDYNVMVMELLGPSLEDLFNFCQRK--------F
....||||.|.||  |..... |...||.|         ..  | .. .   .   |  .  . |. |.  ||||... .| ||| . ...        |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

SLKTVLLLADQMLSRVEFIHCRDYIHRDIKPDNFLMGLGKRGNLVYIIDFGLAKRYRDSKHQHIAYRENKNLTGTARYASINTHRGIEQSR-RDDIESLG
.  ..  .. |... .|..| .  ||||.||.| |.        . |.|||||...             . . ||  | .         .. . |. |.|
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

YVFMYFNRGTLPWQGLKAVTKRQKYELISEKKISTRVDDLCAGYPEAFAQYLNYCRSLGFEEQPDYGYLRNLFRTLFHR--------QQFC-------YD
 ..  .  |  |..     .  . ...|                                        .... | ....        . .          
CILYEMLCGYPPFP-----QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHP

YV
..
WF
Kinase F46F2.2.AA TyrKc 188-451 18 1.1e-08 -82.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 188-451
Range on HMM: 1-280/280
Sequence Identity: 18% (57 aa)

FRLGRKIGSGSFGDIYLGQNIQTNEEVAVKLECVKSKHPQLHIESRLYR--IMLGGIG------IPEIRWCGQEG------DYNVMVMELLGP-SLEDLF
 .||.|.|.| || .|.|. .   ..||||     .       .  ..|   ..  .|      .  .  | |.|      .   .|||.    .| |  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

NFCQRKFSLKTVLLLADQMLSRVEFIHCRDYIHRDIKPDNFLMGLGKRGNLVYIIDFGLAKRYRDS-------KHQHIAYRENKNLTGTARYASINTHRG
  ...|...|. |  . |  .  |..| . .||||.   | | | ..    | | ||||..   |        .  . . .....     |  .      
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA------

IEQSRRDDIESL-GY-------VFMY-------FNRGTLPWQGLKA--VTKRQKYELISEKKISTRVDDLCAG-----YPEAFAQYLNYCRSLGFEEQPD
        .|..  .       |...       | .|  |. |     .. .. .|.. . .   . .. .        |..  |    |     |. | 
--------PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPT

YGYLRNLF
   .. .|
FSEIHECF
Kinase F46F2.2.AA Pkinase_Tyr 188-217 38 7e-07 23.92 Pfam 1-34 (270) Show / Hide 
Range on Protein: 188-217
Range on HMM: 1-34/270
Sequence Identity: 38% (13 aa)

FRLGRKIGSGSFGDIYLGQNI----QTNEEVAVK
 ..|.|.|.|.||..|.|       .|. .||||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVK
Kinase F46F2.2.AA VRK 188-204 64 3e-06 16.35 In-house 1-17 (284) Show / Hide 
Range on Protein: 188-204
Range on HMM: 1-17/284
Sequence Identity: 64% (11 aa)

FRLGRKIGSGSFGDIYL
.|||..||.| || |||
WRLGKPIGQGGFGCIYL