Gene F49C5.4 (Nematode worm)

F49C5.4

Species: Nematode worm
Alias: aSWK045, CE16081, F49C5.4
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: II: 12539963-12541552, WormBase Genetic Map location: II:9.05,

Classification

Group: CAMK
Family: CAMKL
Subfamily: NIM1

Sequence

Name Sequence Type Origin Length Description Download
F49C5.4.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 252 Kinase domain by global Sugen HMM Fasta, JSON
F49C5.4.AA Protein Genbank 334 None Fasta, JSON

Protein domain

Protein domains of F49C5.4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase F49C5.4.AA NIM1 49-300 69 5.3e-245 727.61 In-house 1-258 (258) Show / Hide 
Range on Protein: 49-300
Range on HMM: 1-258/258
Sequence Identity: 69% (179 aa)

YRLGKELGAGNFSKVKLGVHQLTKEKVAVKIMD--KAKMDAKAQKLLSREIQAMEEMNHPNIVKLFEVVETLTRVHLVIEYASGGELYTYVHERGKLTEG
||...|.|.|||||||||||||||||||.||||  |.|||.|.|..||||||.||.|.|||||.|.||||||||||||.|||.||||||..|..|||.|.
YRFCGEIGRGNFSKVKLGVHQLTKEKVAIKIMDLDKTKMDQKTQRMLSREIQCMECMHHPNIVRLYEVVETLTRVHLVMEYARGGELYTHIHQEGKLREI

DAKPLFAQIVSAVSHMHSRNIVHRDIKAENVMFSSPNTVKLVDFGFSCLVDR----EQMLRTFCGSPPYAAPELFQDTSYAGELVDVWALGVLLFFMLIG
..||.||||||||.||||||||||||||||||..|.|.||..||||||....    .|||.||||||||||||||||..|.||.|||||||.||.||..|
HCKPIFAQIVSAVKHMHSRNIVHRDIKAENVMYTSNNCVKVGDFGFSCYCKMGTGANQMLNTFCGSPPYAAPELFQDEHYIGEYVDVWALGILLYFMMTG

VTPFKAETVPDMKVLITAGKYQIPDYVSLLATELIKSMLKTDTGQRADIDSVKKHFWM
|.||.|||||.||..|..|.|||||||||....||..|||....||..||....|.||
VMPFRAETVPKMKKCILKGQYQIPDYVSLPCHRLIRGMLKHIPTQRYTIDQMMNHQWM
Kinase F49C5.4.AA CAMKL 49-300 39 7.70000000001e-138 442.55 In-house 1-297 (297) Show / Hide 
Range on Protein: 49-300
Range on HMM: 1-297/297
Sequence Identity: 39% (118 aa)

YRLGKELGAGNFSKVKLGVH-QLTKEKVAVKIMD--KAKMDAKAQKL-----------LSREIQAMEEMN---HPNIVKLFEVVETLTR------VHLVI
||.||.|| |.|.||||..| ..|.||||.||.|  |...| ...|            . |||| |. .|   ||||.||.||.|| .       ..|| 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYASGGE--LYTYVHER----GKLTEGDAKPLFAQIVSAVSHMHSRNIVHRDIKAENVMFSSPN--TVKLVDFGFSCLVDR-----EQMLRTFCGSPPYA
||.||||  |. |. ..    |...|..|. .| ||||||...||..|||||||.||..... .  ..|..||||| . ..     .|.|.||||||||.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APELFQD--TSYAGELVDVWALGVLLFFMLIGVTPFKAETVP---------DMKVLITAGKYQIPDYVSLLATELIKSMLKTDTGQRADIDSVKKHFWM
|||.||.  ..| |  ||.|..||.|..|. |  ||...|..           |. .. ... |. .||  .  ||..||...  .|. |. ...| ||
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase F49C5.4.AA MARK 49-300 44 9.90000000001e-124 406.24 In-house 1-262 (262) Show / Hide 
Range on Protein: 49-300
Range on HMM: 1-262/262
Sequence Identity: 44% (117 aa)

YRLGKELGAGNFSKVKLGVHQLTKEKVAVKIMDKAKMDA-KAQKLLSREIQAMEEMNHPNIVKLFEVVE--TLTR-VHLVIEYASGGELYTYVHER--GK
|...|..| |...||||..|..|..|||.||..| |..  .. | . |||. |  ..||||.|||.|.|  | .. ..|. ||||||||| |. ..  |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LTEGDAKPLFAQIVSAVSHMHSRNIVHRDIKAENVMFSSPN--TVKLVDFGFSCLVDREQMLRTFCGSPPYAAPELFQDTSYAGELVDVWALGVLLFFML
|.| .|. .| ||||||. .||.||||||||.||..  . .   .|. |||||  .  .|.| ||||.|||.|||.|.   | |  ||.|.|||.|.||.
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

IGVTPFKAET--VPDMKVLITAGKYQIPDYVSLLATELIKSMLKTDTGQRADIDSVKKHFWM
 |  ||.. |    ...  |..|||.||..||  .  ||...|...  .|..|. . || ||
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase F49C5.4.AA CAMK 54-300 26 1.6e-117 380.45 In-house 1-425 (425) Show / Hide 
Range on Protein: 54-300
Range on HMM: 1-425/425
Sequence Identity: 26% (111 aa)

ELGAGNFSKVKLGVHQLTK------------EKVAVKIMDKAKMD--------------------------AKAQKLLSREIQAMEE-------MNHPNI
.|| |.|.||||..| .|.            .|||.||.|| |..                          .| .| . |||. |         ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLFEVVE------------TLTR--------VHLVI---EYASGGEL----YTYVHER---------------GKLTEGDAKPLFAQIVSAVSHMHSRN
.||.|| |            | ..        ...|    ||.|||||    . |. |.               |..|| .|. .| ||.||| ..||.|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDIKAENVMFSSP-----------------NTVKLVDFGFSCLVDR------------------------EQMLRTFCGSPPYAA-PELFQD-----
|||||.| ||.....                  |..|..||||.. .|.                         |...||||.|.|.| ||...      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------TSYAGELVDVWALGVLLFFMLIGVTPFKAE-------------TVPDMKVLITAGKYQ-IPDYVSL-----------------------LAT
          | |. .|.|..||.|..|| |  || ..             . ....  |..|||. .|.|.|                         . 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

ELIKSMLKTDTGQRADIDSVKKHFWM
 ||..||..|  .|. |. ...| ||
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase F49C5.4.AA AMPK 49-300 43 2e-113 338.1 In-house 1-254 (254) Show / Hide 
Range on Protein: 49-300
Range on HMM: 1-254/254
Sequence Identity: 43% (110 aa)

YRLGKELGAGNFSKVKLGVHQLTKEKVAVKIMDKAKM-DAKAQKLLSREIQAMEEMNHPNIVKLFEVV-ETLTRVHLVIEYASGGELYTYVHERGKLTEG
| .|| .| | | |||.|.|.||.||||.||..| |. | . .. ..|||. .  ..||.|..|.||. || |   .|.||.|||||. |.  .|.|.| 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

DAKPLFAQIVSAVSHMHSRNIVHRDIKAENVMFSSPNTVKLVDFGFSCLVDREQMLRTFCGSPPYAAPELFQDTSYAGELVDVWALGVLLFFMLIGVTPF
.|. .|.||.|.|. .|  .||||| | ||. .   . .|.|||| | .    ..|.| |||| |||||. .   |.|  ||.|  || |. || |  ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

KAETVPDMKVLITAGKYQIPDYVSLLATELIKSMLKTDTGQRADIDSVKKHFWM
  | .|.    |..|.|.||...|  | .|||.||..|  .|..|. ...| | 
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase F49C5.4.AA QIK 49-300 38 2.1e-103 349.8 In-house 1-272 (272) Show / Hide 
Range on Protein: 49-300
Range on HMM: 1-272/272
Sequence Identity: 38% (106 aa)

YRLGKELGAGNFSKVKLGVHQLTKEKVAVKIMDKAKMDAKAQKLLSREIQAMEEMNHPNIVKLFEVVETLTRVHLVIEYASGGELYTYVHERGK------
| ... .| |||  |||. |  ||.|||.||.|| ..|..  . . ||.| |  ..||.|.||..| ||     .| ||.|.||.. |. . |.      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------LTEGDAKPLFAQIVSAVSHMHSRNIVHRDIKAENVMFSSPNTVKLVDFGFSCLVDREQMLRTFCGSPPYAAPELFQDTSYAGELVD
              ..| .|.  | ||.||| . |.|||||||.||||... .   .|..||||| .   .|.| |.||||||||||.|.  .| |  ||
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD

VWALGVLLFFMLIGVTPFKAETVPDMKVLITAGKYQIPDYVSLLATELIKSMLKTDTGQRADIDSVKKHFWM
.| .||.|. .  |  ||  .|.. ..  .  ||..|| ..|.   .||. ||  | ..|  |. ...| ||
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase F49C5.4.AA NuaK 49-300 39 1.4e-100 265.11 In-house 1-252 (252) Show / Hide 
Range on Protein: 49-300
Range on HMM: 1-252/252
Sequence Identity: 39% (101 aa)

YRLGKELGAGNFSKVKLGVHQLTKEKVAVKIMDKAKMDAKAQKL-LSREIQAMEEMNHPNIVKLFEVVETLTRVHLVIEYASGGELYTYVHERGKLTEGD
|.. | || | . ||||.. . |  .||.|   | | ....  .   |||. |  .|||.|.. .|| |   .. .|.||||||||| |. |...|.|..
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

AKPLFAQIVSAVSHMHSRNIVHRDIKAENVMFSSPNTVKLVDFGFSCLVDREQMLRTFCGSPPYAAPELFQDTSYAGELVDVWALGVLLFFMLIGVTPFK
|. .| ||||||   |  .|.||| | ||..    . .|  ||| | . . ...| |||||| || ||    . | |  || |.|||||. |  |  || 
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

AETVPDMKVLITAGKYQIPDYVSLLATELIKSMLKTDTGQRADIDSVKKHFWM
 .    ..  |. |.|  |   |  | .||  ||. .  .|| |  . .| |.
GHDFKHLVKQISQGAYYEPCKPS-DACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase F49C5.4.AA S_TKc 49-300 29 2.5e-94 320.59 SMART 1-231 (231) Show / Hide 
Range on Protein: 49-300
Range on HMM: 1-231/231
Sequence Identity: 29% (79 aa)

YRLGKELGAGNFSKVKLGVHQLTKEKVAVKIMDKAKMDAKAQKLLSREIQAMEEMNHPNIVKLFEVVETLTRVHLVIEYASG--GELYTYVHERGK----
|......| | |.||....|  |...||.||..         . . |||| ... .|||||||..| .. .....| ||..|  |.|..| ..||.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LTEGDAKPLFAQIVSAVSHMHSRNIVHRDIKAENVMFSSPNTVKLVDFGFSCLVDREQMLRTFCGSPPYAAPELFQDTSYAGELVDVWALGVLLFFML
  ..| .|. ...||..|. ..||..|.|||.| ||.....  ..|. |||.....      .||||.| | |||..   .| .. .|.|..|..|. ||
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

IGVTPFKAETVPDMKVLITAGKYQIPDYVSLLATELIKSMLKTDTGQRADIDSVKK-------HFWM
 | .||      .|....   .       |  | ..|. .|. |  .|  .  . .       | |.
CGYPPFP-----QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase F49C5.4.AA Pkinase 49-300 27 1.9e-86 298.27 Pfam 1-293 (293) Show / Hide 
Range on Protein: 49-300
Range on HMM: 1-293/293
Sequence Identity: 27% (82 aa)

YRLGKELGAGNFSKVKLGVHQLTKEKVAVKIMDKAKMDAKAQKLLSR--EIQAMEEMNHPNIVKLFEVVETLTRVHLVIEYASGG----ELYTYVH--ER
|..|. .|.|.|..|....|. | ..|||||..| . . . .. . |  ||| | ..||||||.|....|. .....| ||. ||    .|..|..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKL--TEGDAKPLFAQIVSAVSHMHSRNIVHRDIKAENVMFSSPNTV----KLVDFGFSCL--VDREQMLRTFCGSPPYAAPELFQDTSYAGELVDVWAL
|..  .| ..|  . ||.... ..||..|.|||.| ||..... ...    |. |||....    . . . ||||.|.|.|||. .. .| |  ||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLLFFMLIGVTPFKAE----TVPDMKVLITAGKYQIPDYVS------------------------LLATELIKSMLKTDTGQRADIDSVKKHFWM
|..|. || | .||. .    .  |....|   .. .... .                          . ..||..|. |  .|  .. ...| |.
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase F49C5.4.AA CAMK-Unique 49-300 24 1.5e-76 252.17 In-house 1-363 (363) Show / Hide 
Range on Protein: 49-300
Range on HMM: 1-363/363
Sequence Identity: 24% (88 aa)

YRLGKELGAGNFSKVKLGVHQLTKEKVAVKIMDKAKMDAKAQKL------------------LSREIQAMEEMNHPNIVKLFEV----VETLT-------
|.... .| |||..|. .  . |. | |.|.  |..   |.||.                  | ||.| .   .||||.||...    ... .       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------RVHLVIEYASGGELYTYVHE--------------------RGKLTE--GDAKPLFAQIVSAVSHMHSRNIVHRDIKAENVMFSSP-------
        . ..| ||. ||.|. .. .                    .|...|   |.  ......|||..||| .|||||.|.||.|....       
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

---------NTVKLVDFGFSCLVDREQMLR---TFCGSPPYAAP--------------ELFQDTSYAGELV---DVWALGVLLFFMLIGVTPFKAETVP-
         . .|| ||| .|...  .|     |.||.|.|.||              |.     | . .    | |.|||....|| | .|| .|. . 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------DMKVLITAGKY--------QIPDYVSLLATELIKSMLKTDTGQRADIDSVKKHFWM
            |..|.|        ..|||.|  |. ..|  ...|  .|  .   ..| | 
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase F49C5.4.AA RSK 51-300 30 7.7e-75 254.94 In-house 1-278 (278) Show / Hide 
Range on Protein: 51-300
Range on HMM: 1-278/278
Sequence Identity: 30% (84 aa)

LGKE--LGAGNFSKVKLGVHQLTKEKVAVKIMDKAKMDAKA--QKLLSREIQAMEEMN-HPNIVKLFEVVETLTRVHLVIEYASGGELYTYVHERGK---
|     .| | .. ..  .|  |.   |.|. .|||.....  ..   .|.. .|. . ||.||.|... .| . ..|. || .||||.|   ...    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LTEGDAKPLFAQIVSAVSHMHSRNIVHRDIKAENVMFSS---PNTVKLVDFGFSCL--VDREQMLRTFCGSPPYAAPELFQ----DTSYAGELVDVWALG
..| .|.  .|.||.||.|.|.. |.|||.| ||... .   . ..||.||||...   | .|.. |||..  |.|||.      .  . .. .|.| ||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGH-DKACDWWSLG

VLLFFMLIGVTPFKA---ETVPDMKVLITAGK--YQIP--DYVSLLATELIKSMLKTDTGQRAD-----IDSVKKHFWM
||.. || | .||..   ..  .    |  ||    .|  .|.|  | .||. ||. |  .|       .. .|.| |.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase F49C5.4.AA Ciliate-E2 49-300 23 2.3e-74 253.34 In-house 1-365 (365) Show / Hide 
Range on Protein: 49-300
Range on HMM: 1-365/365
Sequence Identity: 23% (89 aa)

YRLGKELGAGNFSKVKLGVHQLTKE------------------KVAVKIMDKAKMDAKAQKLLSREIQAMEEMN----------------HPNIVKLFEV
| . | .| |||..|... . ....                  ||..||  .  |  .  . ...||. | |.|                ||||.|..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VE--TLTRVHLVIEYASGGELYTYVHER-----------GKLTEGDAKPLFAQIVS---------------AVSHMHSRN-IVHRDIKAENVMFSSPNTV
 .  . . . || ||..||.|. |  ..           ...||  .| ...||..               |. ..||.| |.||||| ||..|     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLVDFGFSCLVDRE--------------------------------QMLRTFCGSPPYAAPELFQDTSYAG--------ELVDVWALGVLLFFMLIGVTP
|..|||.|  .| .                                .| .|.||.|.| ||| ..  .| .        . .|.|.|||.|..|| | .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FKAETVPDMKVLITAGKYQIP------------------DYVSLLATELIKS----MLKTDTGQRAD-IDSVKKHFWM
|           |  .|...|                  ...|. .  |||     ||. |  .| . .. ...| |.
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase F49C5.4.AA Pkinase_Tyr 49-191 31 3.1e-25 86.1 Pfam 1-156 (270) Show / Hide 
Range on Protein: 49-191
Range on HMM: 1-156/270
Sequence Identity: 31% (49 aa)

YRLGKELGAGNFSKVKLGVHQ----LTKEKVAVKIMDKAKMDAKA--QKLLSREIQAMEEM-NHPNIVKLFEVVE-TLTR--VHLVIEYASGGELYTYVH
 ..||.||.|.| .|..|.       || .||||.. | . . ..  .. . ||.. | .. .|||||.|  |.        . .| ||. .| |..| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

E----RGKLTEGDAKPLFAQIVSAVSHMHSRNIVHRDIKAENVMFSSPNTVKLVDFG
.    ...||  |     .|| .. .. .|.|..|||. | |.. ...|.||  |||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase F49C5.4.AA TyrKc 49-298 23 5e-17 52.55 SMART 1-280 (280) Show / Hide 
Range on Protein: 49-298
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

YRLGKELGAGNFSKVKLGVHQLTKEKVAVKIMDKAKMDAKAQKLLSREIQAMEEM--NHPNIVKLFEVVETL-------TRVHLVIEYASGGELYTYVHE
 .|||.|| |.| .| .|.     ..|||| . . .     .. . ||.. | .   .|||||.|. |. .          . .| ||...| |  | ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

RGK-LTEGDAKPLFAQIVSAVSHMHSRNIVHRDIKAENVMFSSPNTVKLVDFGFSCLVDRE-------QMLRT-F--CGS--PPYA--APELFQDTSYAG
... |.  |      || .  .. ||.|..|||. | |.. ....|||  ||| |  .. .       .. |.    .|    |.   ||| ...  .  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF-T

ELVDVWALGVLLF--FMLIGVTPFKA-----ETVPDMKVLITAG-KYQIPDY---------VSLLATELIKSMLKTDTGQRADIDSVKKHF
.  |||. ||...  | . | .|         .  ..  .. .|    .|..          . . . ..|.  . |  .|     ... |
TKSDVWSFGVCMWEIFTY-GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF