Gene F52C12.2 (Nematode worm)

F52C12.2

Species: Nematode worm
Alias: CE31534, aSWK210, F52C12.2A, F52C12.2
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: IV: 1953582-1956647, WormBase Genetic Map location: IV:-11.7,

Classification

Group: Other
Family: Bud32

Sequence

Name Sequence Type Origin Length Description Download
F52C12.2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 218 Kinase domain by global Sugen HMM Fasta, JSON
F52C12.2.AA Protein Genbank 557 None Fasta, JSON

Protein domain

Protein domains of F52C12.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
RLI F52C12.2.AA RLI 61-95 48 8e-17 60.49 Pfam 1-35 (35) Show / Hide 
Range on Protein: 61-95
Range on HMM: 1-35/35
Sequence Identity: 48% (17 aa)

FRLAMYDFNQCDPKRCSGRKLLRANLITEVKLGQR
.|.||.|..|||||.|.|||. | ....||..|..
MRIAMWDYDQCDPKKCTGRKCIRFCPVREVRMGKK
DUF367 F52C12.2.AA DUF367 99-226 49 2.1e-68 224.52 Pfam 1-131 (131) Show / Hide 
Range on Protein: 99-226
Range on HMM: 1-131/131
Sequence Identity: 49% (65 aa)

LVLSPTGTYTLAPRDRPFVEQNGLCVVDCSWKEVERTPLHRVKA---PEHRLLPYLVAANSVNYGKPCHLTCAEAMAAGLYILGFQEAASRLMKPFSWGD
.||.| .  .. | ||  ||. |.|||||||......|  ...    . .|.||.||||| ||||||| | |.|| || |||.||.. |. ||  |.|| 
VVLNPYAQICVSPEDRDIVERHGICVVDCSWNRIDEMPFKKIRFQTARHERRLPFLVAANPVNYGKPCKLSCVEAFAACLYICGFWDWAWWLMSKFKWGH

HFIELNKELLDLYAACDTPEDVIRAQNEYLE
.|.|||||||. |..|.   .....||||||
TFLELNKELLEEYSQCENSMEIVEIQNEYLE
Kinase F52C12.2.AA Bud32 340-555 44 2.1e-156 504.19 In-house 1-269 (269) Show / Hide 
Range on Protein: 340-555
Range on HMM: 1-269/269
Sequence Identity: 44% (121 aa)

IDGLLY---------QGAEAKV--------------TKCIWLGR------QAIIKERFSKGYRHPTLDTQLNKARTKQEIRGLNKARELGIHVPAVYFID
....||         |||||.|              |.|...||      |.||||||.|.||||.||.||.|.|||||.|..|..|..||.||.|||.|
MSLELYKDVDIAPISQGAEARVFYTCYLTVSKQKVYTTCNFQGRAKDSHQQCIIKERFPKAYRHPQLDQQLTKHRTKQEVRAMNRCRKAGICVPYVYFCD

NEKNQLIMEFV---PG----STAKNWISQLNP----ADFDAKTREFGQIFGEKLGKLHRGGLIHGDLTTSNIILR-DDDLQK-----MTFIDFGLSSQGK
|......||..   ||    .|.||.|.|...    ...|...|||....|...||.|....|||||||||..|| ... ..     |..||||||....
NYNHCIYMEYIEESPGGHGFYTVKNYIWQHQETQKEDQHDQCLREFCKKVGRQIGKMHWNHIIHGDLTTSNMMLRHPYADWTKLYGQMHLIDFGLSYISN

VTPEEKGVDLYVLERAVISTHDKCAA-----LIEGLMEGYKKADGK--QFVAVEKKLNEIRLRGRKRDM
..||.|||||||||||..|||.||..     ..|..||.|.|.|.|  .|.||.||.||.|||||||.|
SVPEDKGVDLYVLERAFLSTHPKCEQKYNAWIFEHFMENYRKQDTKCKKFKAVLKKFNEVRLRGRKRTM
Kinase F52C12.2.AA Dicty3 453-491 23 2.1e-07 20.31 In-house 124-187 (351) Show / Hide 
Range on Protein: 453-491
Range on HMM: 124-187/351
Sequence Identity: 23% (15 aa)

LGKLHRGG-LIHGDLTTSNIILRDDD------------------------LQKMTFIDFGLSSQ
| ..|. . .||.|... ||.| .|                           .  .||||||..
LNYIHKNCHIIHRDIKCDNIMLDNDEQHQCNNNNNKMSSTCRDIQCYYSNEINWKLIDFGLSKN
Kinase F52C12.2.AA Ciliate-E8 456-489 41 2e-06 15.83 In-house 105-138 (138) Show / Hide 
Range on Protein: 456-489
Range on HMM: 105-138/138
Sequence Identity: 41% (14 aa)

LHRGGLIHGDLTTSNIILRDDDLQKMTFIDFGLS
||    || |.   ||... .|  |   |||| |
LHNNNIIHCDFKLNNILVQRNDDTKIKIIDFGFS
S_TKc F52C12.2.AA S_TKc 338-537 17 5.9e-05 -104.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 338-537
Range on HMM: 1-231/231
Sequence Identity: 17% (44 aa)

YQIDGLLYQGAEAKVTKCIWLG--RQAIIKERFSKGYRHPTLDTQLNKARTKQEIRGLNKARELGIHVPAVYFIDNEKNQLIMEFVPG--STAKNWISQL
|.|  .. .|| .|| ||.. .  |.  ||.                  ....||. | | .   |     .| | ..  ..||...|   . .  | . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKR

NPAD----FDAKTREFGQIFGEKLGKLHRGGLIHGDLTTSNIILRDDDLQKMTFIDFGLSSQ------------------GK------------------
..      |.  .| . .   . |  .|. | || ||  .|| | .        .||||. |                  ||                  
GRHGLRFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCG

VTPEEKGVDLYVLERAVISTHDKCAALIEGLME-------GYKKADG-------KQFV
 .| .   ..... . .    . .  .|.....       .  .|          ...
YPPFP---QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
RIO F52C12.2.AA RIO 311-526 16 0.000162 -90.33 SMART 1-253 (253) Show / Hide 
Range on Protein: 311-526
Range on HMM: 1-253/253
Sequence Identity: 16% (44 aa)

FKMTAATTSS--DSEGEMDFETTIETGFGYQID--GLL--------Y---------QGAEA-----KVTKCIWLGRQAIIK--ERFSKGYRHPTLDTQLN
.|.  || .   |.   |   ...  |  . |.  |..        |          | |.     .....    ..  |.  .||..| .|..   .. 
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHG-YHHINWRKMV

KARTKQEIRGLNKARELGIHVPAVYFIDNEKNQLIMEFVPG-STAKNWISQLNPADFDAKTR-EFGQIFGEKLGKLHRGG-LIHGDLTTSNIILR---DD
.. .. | | |... | |. .| .  |..... |.|||. . . .    . ... ..... . |  .   |   |. . . |.|.||   |...    |.
RLWAEKEFRNLQRMYEAGVPCPKP--IAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDE

DLQKMTFIDFGLSSQGKVTPEEKGVDLYVL----------ERAVISTHDKCAALIEGLME
.  |  .||.. |    |.... . . .            .|  ... |    ..|.  .
NDCKVWIIDWSQS----VECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG
Kinase F52C12.2.AA NZAK 456-489 41 0.000389 9.23 In-house 121-152 (329) Show / Hide 
Range on Protein: 456-489
Range on HMM: 121-152/329
Sequence Identity: 41% (14 aa)

LHRGGLIHGDLTTSNIILRDDDLQKMTFIDFGLS
||. . || |....|.||  |  ...  |||| |
LHKHHIIHRDIKSNNVIL--DFNKNLKLIDFGSS
Kinase F52C12.2.AA Ciliate-E2 456-491 35 0.000428 9.93 In-house 176-205 (365) Show / Hide 
Range on Protein: 456-491
Range on HMM: 176-205/365
Sequence Identity: 35% (13 aa)

LHRGG-LIHGDLTTSNIILRDDDLQKMTFIDFGLSSQ
||  .  || |.  .||..          |||||| .
LHSKNNIIHRDIKPENILF-------IKIIDFGLSKK
Kinase F52C12.2.AA LRRK 453-491 26 0.000611 9.81 In-house 177-229 (351) Show / Hide 
Range on Protein: 453-491
Range on HMM: 177-229/351
Sequence Identity: 26% (14 aa)

LGKLHRGG--LIHGDLTTSNIIL-RDD---------DLQKMTFIDFGLSS--Q
...||.    .|| ||.. ||.| . .         . .. . .|||.|.  |
MEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQ
Kinase F52C12.2.AA STE 456-491 33 0.000629 9.9 In-house 168-196 (359) Show / Hide 
Range on Protein: 456-491
Range on HMM: 168-196/359
Sequence Identity: 33% (12 aa)

LHRGGLIHGDLTTSNIILRDDDLQKMTFIDFGLSSQ
||. . || |.  .|| |          .|||...|
LHSHHIIHRDIKPANILL-------VKLCDFGVCGQ
Kinase F52C12.2.AA Ciliate-E2-Unclassified 453-491 33 0.0008 9.17 In-house 156-196 (352) Show / Hide 
Range on Protein: 453-491
Range on HMM: 156-196/352
Sequence Identity: 33% (14 aa)

LGKLHRGG-LIHGDLTTSNIILRDDDLQ--KMTFIDFGLSSQ
| .||. .  || |.. .||.. |.. .  .   ||||.|..
LEYLHHKNNIIHRDIKPENILF-DNNGKNYYIKIIDFGISKK
Kinase F52C12.2.AA Ciliate-A1 456-491 36 0.000952 8.56 In-house 117-150 (301) Show / Hide 
Range on Protein: 456-491
Range on HMM: 117-150/301
Sequence Identity: 36% (13 aa)

LHRGGLIHGDLTTSNIILRDDDLQKMTFIDFGLSSQ
.|    .| ||   ||.. .||  |  ..|.|.| |
IHDHNILHRDLKPQNILIHFDD--KWKICDLGMSKQ
Kinase F52C12.2.AA APH 460-492 22 0.003324 11.81 Pfam 171-205 (248) Show / Hide 
Range on Protein: 460-492
Range on HMM: 171-205/248
Sequence Identity: 22% (8 aa)

GLIHGDLTTSNIILR--DDDLQKMTFIDFGLSSQG
...|||.   |....  .|. .   .||.. .  |
CWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWG
Kinase F52C12.2.AA APH 383-458 22 0.539839 4.27 Pfam 35-112 (248) Show / Hide 
Range on Protein: 383-458
Range on HMM: 35-112/248
Sequence Identity: 22% (19 aa)

KARTKQEIRGLNKARELGI--HVPAVYF--IDNEKNQL---IMEFVPGSTAKNWISQLNPA-DFDAKTREFGQIFGEKLGKLHR
... ..|.| |   ...||  .||.|.    |.| . .   .||..|| .. .|      . . .| ...... ... |..||.
AEELHREHRWLRHLAAHGIPVPVPRVLWGCTDDEFHGWPWYLMEWLPGEDLWRW------HALHCAQRPALLEALARFLARLHQ