Gene F57B9.8 (Nematode worm)
F57B9.8
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| F57B9.8.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 255 | Kinase domain by global Sugen HMM | Fasta, JSON |
| F57B9.8.AA | Protein | Genbank | 444 | None | Fasta, JSON |
Protein domains of F57B9.8.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| SH2 | F57B9.8.AA | SH2 | 6-91 | 36 | 5.5e-28 | 100.21 | SMART | 1-87 (87) | Show / Hide |
Range on Protein: 6-91 Range on HMM: 1-87/87 Sequence Identity: 36% (34 aa) QPFFHGLLPREEVKLLLQKN----GDYLMRTSEPQGQARHLIISVMQNETSQEVAHYVIRTSD-GAYSITD--KIKFGTLTELVNHHKQAKIS ||..|| ..|||. ||... ||.| | ||. .......||. . ..| ||.||..| | |.|.. . || .| |||||... ... QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES--NPGDYVLSVRWK---GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG |
|||||||||
| SH2 | F57B9.8.AA | SH2 | 8-85 | 34 | 4.2e-21 | 63.79 | Pfam | 1-81 (81) | Show / Hide |
Range on Protein: 8-85 Range on HMM: 1-81/81 Sequence Identity: 34% (29 aa) FFHGLLPREEVKLLLQK----NGDYLMRTSEP-QGQARHLIISVMQNETSQEVAHYVIRTSDGA-YSITDKIKFGTLTELVNHH ..|| ..|.|. ||.. .|..| | || .|. .||. . ....| ||.|.. |. | ||.. ||..| |||.|. WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGD---YTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY |
|||||||||
| Kinase | F57B9.8.AA | Fer | 115-368 | 44 | 4.2e-141 | 475.08 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 115-368 Range on HMM: 1-283/283 Sequence Identity: 44% (125 aa) ITMTKVLGEGAFGEVKLG--TLKMGS-TTVDV---AIKVAKL--EKVTKEQIKEIITEARLMRG-FDHKNVVKCYGVAAIDEPLLVVMELVPGGALDKYL .|..|.|||||||||..| |||.. ....| |.||.|. |..|||||||. |||.|| .||.||||.|||.. ..|...|||...||.||.|| VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL QKNSS-VQWP-EKLDIIAQVAAGLAYIHSKNIIHRDIAARNILYGKGVAK----VSDFGLSRV----GTEYQMD-PSKRVPIRWLSPETIVSFLYTPQTD .||.. . . ||.....|.|.|..|.||||.|||||||||.||.|.. | .||||.|| |. |.|. ....||||||.|||. ...|.| || KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD VFAFSILCWEVIENGAQPYPE----MLVVQVH----QKVGRDDYRMPISQKAPAMLADVIK-KCWIRDPQQRPTMSQVVQMMY |..|...|||. .|||.|||. | . .|. ... ...|.||. . .| .. ... .|| .|| .||||....|... VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK |
|||||||||
| Kinase | F57B9.8.AA | TyrKc | 115-367 | 35 | 7.4e-115 | 388.79 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 115-367 Range on HMM: 1-280/280 Sequence Identity: 35% (103 aa) ITMTKVLGEGAFGEVKLGTLKMGSTTVDVAIKVAKLEKVTKEQIKEIITEARLMRGF--DHKNVVKCYGVAAID-------EPLLVVMELVPGGALDKYL ||. |.||||||||| .||.| ..||.|. | .. ..... |||.|. . .|.|.|..|||. . |||..|||..|.|.|..|| ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL QKNSS-VQWPEKLDIIAQVAAGLAYIHSKNIIHRDIAARNILYGKGV-AKVSDFGLSRVGTEY--------QMDP----SKR--VPIRWLSPETIVSFLY .|. ......|.. |.|.| .|.||||.||||.||||.|.|.. .|.||||||| .... .. ... .||||..||.| . RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF TPQTDVFAFSILCWEVIENGAQPYPE-----MLVVQVHQKVGRDDYRMPISQK--------APAMLADVIKKCWIRDPQQRPTMSQVVQMM |...||..| ...||. .|.||||. | .|...| .. ||||. . .|. . ...|.|| .|| .|||.|.... . TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV-KQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
|||||||||
| Kinase | F57B9.8.AA | Pkinase_Tyr | 115-367 | 38 | 8.8e-112 | 379.2 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 115-367 Range on HMM: 1-270/270 Sequence Identity: 38% (103 aa) ITMTKVLGEGAFGEVKLGTLK--MGSTTVDVAIKVAKLEKVTKEQ--IKEIITEARLMRGF-DHKNVVKCYGVAA-IDEP--LLVVMELVPGGALDKYLQ ||. |.|||||||||..||.| ...|...||.|. |. ..|| ... . ||..|. . .|.|.|..||| .|| ...|||..|.| |..||. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR K----NSSVQWPEKLDIIAQVAAGLAYIHSKNIIHRDIAARNILYG-KGVAKVSDFGLSRVGTE---Y-QMDPSKRVPIRWLSPETIVSFLYTPQTDVFA | . .. ...|.. .|.|.|..| .|||.||||.||||.| . ..|.|..||||.| .. | .. . ..||.|..|| | .| ..|| . KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS FSILCWEVIENGAQP-YPEMLVVQVHQKVGRDDYRMPISQKAPAMLADVIKKCWIRDPQQRPTMSQVVQMM | .|.||.. |.|| ||.| .| .....| ||||. ...|. . |..|.|| ||..|||.|...... FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
|||||||||
| Kinase | F57B9.8.AA | TK | 115-367 | 19 | 1.5e-93 | 313.98 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 115-367
Range on HMM: 1-486/486
Sequence Identity: 19% (95 aa)
ITMTKVLGEGAFG---EVKLGTLKMGS-----------------------TTVDVAIKVAKLE-KVTKEQIKE--------------IITEARLMRG--F
||. |.||||.|| || .|...... ....||.|. |.. ..|. .. |. .|. .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
DHKNVVKCYGVAAID------------EPLLVVMELVPGGA----LDKYLQKNSS---------------------------------------------
.|.|.|..||| . ||...|||..|.| |..||.|..
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
-------------------------------VQWPEKLDIIAQVAAGLAYIHSK------NIIHRDIAARNILYGKG------------VAKVSDFGLSR
. ...| . .|.|.|..|.||| |..|||.||||.| |.. |.|..||||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR
V----------------------------------GTEYQMD-PSKRVPIRWLSPETIVSFL---------YTPQTDVFAFSILCWEVIENG-AQPYPEM
. ...| .. .. ..||||..||.. . .|...||..| .|.||. .| ...|..|
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM
LV---------VQVHQKVGRD-----------DYRMPIS--QKAP--------------AMLADVIKKCWIRDPQQRPTMSQVVQMM
.| ... | |||. . .| ....|....|| .||..|||.||.....
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
|
|||||||||
| Kinase | F57B9.8.AA | UTK | 115-367 | 30 | 5.1e-80 | 272.16 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 115-367 Range on HMM: 1-296/296 Sequence Identity: 30% (91 aa) ITMTKVLGEGAFGEVKLGTLKMGS---TTVDVAIKVAKLEKVTKEQIK---EIITEAR---LMRGFD-HKNVVKCYGVAAIDEPLLVVMELVPGGALDKY . . ||.|||||| ..... | ...|||.||.. .... . ... ||| .| |. | ||.. .|| .||...|.|. ..| |..| VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY LQKNSS--------VQWPEKLDIIAQVAAGLAYIHSKNIIHRDIAARNILYGKG--------VAKVSDFG---LSRVGT------------EYQMDPSKR |.... . ..|. ...|.|..|.||....|||.||||.| .. |.|..||| .|| .|.... .| LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR VPIRWLSPETIVSF-LYTPQTDVFAFSILCWEVIENGAQPYPEMLVVQVHQKVGRDD-YRMPISQKAPAMLADVIKKCWIRDPQQRPTMSQVVQMM .|||| .|| ... .| ..||..| ..|||. .|..|||.| .|| . |.. . |||| . |. . .. ..|| ||| ||.. ..|| | WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM |
|||||||||
| Kinase | F57B9.8.AA | TK-Unique | 115-367 | 28 | 3.5e-65 | 222.86 | In-house | 1-294 (294) | Show / Hide |
Range on Protein: 115-367 Range on HMM: 1-294/294 Sequence Identity: 28% (83 aa) ITMTKVLGEGAFGEVKLGTLK---MGSTTVDVAIKVAKLEKVTKEQIKEIITEARLMRGFD-HKNVVKCYGVAA-IDEPLLVVMELVPGGALDKYLQKNS ... .|.||||||.| |... ... .... .. ...|... .. |...|. . |.|.|.|.|. ||| . .|| .|.| |..||... LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR SVQWPEK--------------------LD------IIAQVAAGLAYIHS--KNIIHRDIAARNIL-YGKGVAKVSDFGLSR---VGTEYQMD-PSKRVPI .. . .. .. |.| |..|..| |.|.|||..|||.| ...|.|..|||..| ...|.| ..|.|| PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI RWLSPETIV--SFLY-TPQTDVFAFSILCWEVIENGAQPYPEMLVVQVHQKVGRDDYRMPISQKA-PAMLADVIKKCWIRDPQQRPTMSQVVQMM ||..|| . | |...|| .| .| ||. .||.|||.| .. ... || |||| .. . . ..| || ..|..||. .|.... RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECI-RDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL |
|||||||||
| Kinase | F57B9.8.AA | Src | 115-367 | 36 | 1.4e-62 | 211.39 | In-house | 1-255 (255) | Show / Hide |
Range on Protein: 115-367 Range on HMM: 1-255/255 Sequence Identity: 36% (96 aa) ITMTKVLGEGAFGEVKLGTLKMGSTTVDVAIKVAKLEKVTKEQIKEIITEARLMRGFDHKNVVKCYGVAAIDEPLLVVMELVPGGALDKYLQ---KNSSV |.. . ||.| |||| |. . ...||.|. | |. || .| ..|...|. | | .|| . | |. | | .||. . ... IKLCRKLGQGQFGEVWMGYWNG---NTKVAVKTLKPGTMSPEAFL---QEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHL QWPEKLDIIAQVAAGLAYIHSKNIIHRDIAARNILYGKG-VAKVSDFGLSRVGT----EYQMDPSKRVPIRWLSPETIVSFLYTPQTDVFAFSILCWEVI . |. .|. ||||.| ||. |.|.|||| ||||.| |.. |.|| |||| |. || . ..||.| || | .| .|| | || .|.. HLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIV ENGAQPYPEMLVVQVHQKVGRDDYRMPISQKAPAMLAD-VIKKCWIRDPQQRPTMSQVVQMM | ||| | .| |.| | |||| .. |. | . ....|| .||.|||| . . TYGRVPYPGMTNHEVLQQVERG-YRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL |
|||||||||
| Kinase | F57B9.8.AA | TKL | 121-367 | 20 | 7e-62 | 211.9 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 121-367
Range on HMM: 1-364/364
Sequence Identity: 20% (77 aa)
LGEGAFGEVKLGTLKMGS------TTVDVAIKVAKLEKVTKEQI-------------------------KEIITEARLMRGFDHKNVVKCYGVAAIDEP-
.|.|.|||| |... . | |||.|. | . . .. . .... |...|. ..| |.|...|.. ..
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
------------LLVVMELVPGGALDKYLQKNSSVQWPEKLDIIAQVAAGLAYIHS--------KNIIHRDIAARNILYGK-GV--------------AK
| |||..||| | ||. |. ..... ..| |..| || ..|||||. .||| . . .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK
VSDFGLSRVGTEY-QMDPSK------------------RV-PIRWLSPETIV----------------SFLYTPQTDVFAFSILCWEVIE----NGAQPY
..||||||. .. .| .. .. .||..|| . .| |....||..| |. ||.. .||
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY
PEMLVV----QVHQKVGRDDYRMPIS------------QKAPAMLADVIKKCWIRDPQQRPTMSQVVQMM
..|.. . .|. . .| || .| ... ...|| ||..||....... .
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
|
|||||||||
| Kinase | F57B9.8.AA | SFK-Src | 115-359 | 36 | 1e-58 | 172.39 | In-house | 1-247 (259) | Show / Hide |
Range on Protein: 115-359 Range on HMM: 1-247/259 Sequence Identity: 36% (93 aa) ITMTKVLGEGAFGEVKLGTLKMGSTTVDVAIKVAKLEKVTKEQIKEIITEARLMRGFDHKNVVKCYGVAAIDEPLLVVMELVPGGALDKYLQK--NSSVQ | . | ||.| ||.| |. | .||.| | . | | || .|. | | .. | | . ||. .. ||. | | ||. | . IRLEKKLGSGQFGDVWKGRWNN---TTEVAVKTLKPGAMSAE---EFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLR WPEKLDIIAQVAAGLAYIHSKNIIHRDIAARNILYGKG-VAKVSDFGLSRV---GTE-YQMDPSKRVPIRWLSPETIVSFLYTPQTDVFAFSILCWEVIE | | ||||.|.|| .| .||| ||||.| | | || |||.||| | | . ||.| || . || .| || |.. MPQLVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVT NGAQPYPEMLVVQVHQKVGR-DDYRMPISQKAPAMLADVIKKCWIRDPQQRPT | ||| | | |.| | . |||| . | . . ||. | ||| YGRIPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPT |
|||||||||
| Kinase | F57B9.8.AA | Frk | 115-371 | 35 | 3.7e-57 | 196.22 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 115-371 Range on HMM: 1-260/260 Sequence Identity: 35% (95 aa) ITMTKVLGEGAFGEVKLGTLKMGSTTVDVAIKVAKLEKVTKEQIKEIITEARLMRGFDHKNVVKCYGVAAIDEPLLVVMELVPGGALDKYLQ----KNSS | . . || | |||| | |. ||.| | . .. . ||..|. | ... | | ...||.... ||. |.| .||| | .. IQLIRRLGSGQFGEVWEGLWNN---TTPVAVKTLKPGTM---DPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQ VQWPEKLDIIAQVAAGLAYIHSKNIIHRDIAARNILYGKG-VAKVSDFGLSR---VGTE--YQMDPSKRVPIRWLSPETIVSFLYTPQTDVFAFSILCWE .| .. .|. ||||||.||. |.| ||||.||||.| |.. . |. |||| | . | | |.||.| || . . .| . ||..| || | CQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTE VIENGAQPYPEMLVVQVHQKVGRDDYRMPISQKAPAMLADVIKKCWIRDPQQRPTMSQVVQMMYEIT .| | ||| | .| | | . .|||| | | ... .|| ||..||| . . . IITYGRMPYPGMTNAEVLQMVDH-GYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF |
|||||||||
| Kinase | F57B9.8.AA | Src-Echino1 | 115-367 | 35 | 4.3e-53 | 182.51 | In-house | 1-252 (252) | Show / Hide |
Range on Protein: 115-367 Range on HMM: 1-252/252 Sequence Identity: 35% (93 aa) ITMTKVLGEGAFGEVKLGTLKMGSTTVDVAIKVAKLEKVTKEQIKEIITEARLMRGFDHKNVVKCYGVAAIDEPLLVVMELVPGGALDKYLQKNSSV--Q |.| .|.| .||| | . | | .||.| | . ... . . || .|. |...|. | | . ||. .| ||. | | .||... . . LRMDKKIGKGHCGEVWKG-VWNGNT--PVAVKTLKEKTMSPA---DFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVK WPEKLDIIAQVAAGLAYIHSKNIIHRDIAARNILYGKG-VAKVSDFGLSRV--GTEYQMDPSKRVPIRWLSPETIVSFLYTPQTDVFAFSILCWEVIENG .. .|. |..|.|. |. |||..|||.||||.| ||| | |. |||| |. .| ..||.| .|| .. .| . ||..| || |.. | MTTLIDMGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFG AQPYPEMLVVQVHQKVGRDDYRMPISQKAPAMLADV-IKKCWIRDPQQRPTMSQVVQMM |||.| .| ..| | |||| .. | | .. . ||| .|||||||. . . . RYPYPGMMNREVLDQVDR-GYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF |
|||||||||
| Kinase | F57B9.8.AA | Eph | 115-367 | 35 | 8.2e-53 | 175.68 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 115-367
Range on HMM: 1-264/264
Sequence Identity: 35% (94 aa)
ITMTKVLGEGAFGEVKLGTLK--MGSTTV---DVAIKVAKLEKVTKEQIKEIITEARLMRGFDHKNVVKCYGVAAIDEPLLVVMELVPGGALDKYLQKNS
|...||.|.| |||| |.|| | . | |||| | . | | . .|| .| ||| |... || . .|. .| | |.||..| ..
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLK-AGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHD
SVQWPEKL-DIIAQVAAGLAYIHSKNIIHRDIAARNILYGKG-VAKVSDFGLSRV-------GTEYQMDPSKRVPIRWLSPETIVSFLYTPQTDVFAFSI
. .| .. .|.| | . | .||| |||||| . | |||||||||| .| . ..|||| ||.| .|. || . |
GQFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTR-GGKIPIRWTAPEAIAYRKFTSASDVWSYGI
LCWEVIENGAQPYPEMLVVQVHQKVGRDDYRMPISQKAPAMLADVIKKCWIRDPQQRPTMSQVVQMM
. |||. | || .| | . . ..|| | |. | ..|| .|...||. .|.| ..
VMWEVMSYGERPYWDMSNQDVIKAI-EQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
|
|||||||||
| Kinase | F57B9.8.AA | Pkinase | 115-367 | 22 | 2.3e-48 | 171.81 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 115-367 Range on HMM: 1-293/293 Sequence Identity: 22% (66 aa) ITMTKVLGEGAFGEVKLGTLKMGSTTVDVAIKVAKLEKVTKEQIKEIIT--EARLMRGFDHKNVVKCYGVAAIDEPLLVVMELVPGG----ALDKYLQ-- .. ...|.|.||.|.... | . ||.|. |... ... .. . |...|. ..|.|.|..|.. . . .|||...|| | |.. YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW KNSSV--QWPEKLDIIAQVAAGLAYIHSKNIIHRDIAARNILYG-KGVA----KVSDFGLSRV--GTEYQMDPSKRVPIRWLSPETIV-SFLYTPQTDVF .. .. .. | ... |.. ||.|.||..|||||. |||. .|. |..||||... .. . . .....|| | . |.| |.. RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW AFSILCWEVIENGAQPYPEM------LVVQVHQKVGRDDYRMPISQKAP-------------------AMLADVIKKCWIRDPQQRPTMSQVVQM--M .. ....|.. | |.|. |....... ... ..... . . |.||.|. .||..||| |..| . SCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
|||||||||
| Kinase | F57B9.8.AA | S_TKc | 115-371 | 25 | 8.2e-48 | 166.08 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 115-371
Range on HMM: 1-231/231
Sequence Identity: 25% (69 aa)
ITMTKVLGEGAFGEVKLGTLKMGSTTVDVAIKVAKLEKVTKEQIKEIITEARLMRGFDHKNVVKCYGVAAIDEPLLVVMELVPG--GALDKYLQKNSS--
.. ...|.||||.|.... | | ||||. | . |. | .... .|.|.||.|.| . | .|||...| | | .|..|. .
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG
----VQWPEKLDIIAQVAAGLAYIHSKNIIHRDIAARNILYGKGVAKVSDFGLSRVGTEYQMDPSKRVPIRWLSPETIVSFLYTP-QTDVFAFSILCWEV
. ...|.. .|.|.||..|||||. ||| . . |..||||.|. . . ...|| . |.. |. .. .. .|
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM
IENGAQPYPEMLVVQVHQKVGRDDYRMPISQKAPAMLADVIKKCWIRDPQQRPTMSQVVQ-----MMYEIT
. | |.| . .. .|.| . . | |.||. .||..||| .. | .. .
LC-GYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
|
|||||||||