gcy-2

Species: Nematode worm
Alias: R134.2, CE25080, gcy-2, aSWK299
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: II: 9511999-9507508, WormBase Genetic Map location: n/a,

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
gcy-2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 228 Kinase domain by global Sugen HMM Fasta, JSON
gcy-2.AA Protein Genbank 1118 None Fasta, JSON

Protein domain

Protein domains of gcy-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ANF_receptor gcy-2.AA ANF_receptor 56-435 19 2.7e-66 231.38 Pfam 1-364 (364) Show / Hide
Range on Protein: 56-435
Range on HMM: 1-364/364
Sequence Identity: 19% (78 aa)

VCGGAVPMAIERLREFGYVKDFDFEFIVDYTEC----DQGSVVRAGIEFIKTHKVDVIIGPPCAQALRVMSFLAENYKKPVLGWGFVSDTDLSD--VIRF
 |..|..||||..   . . ...... .....|    |    | |. .... ..|..|||| | .. . .. .|. ...|...|| .... |.|   .|.
QCAPAMRMAIEDINADPGILLPGITLGYHDDDCCYCSDC-QAVAAADCCWH-KGVVAIIGPSCSYVCIPVARIANHWNIPMISWG-CTCPCLTDKAKNRY

PYLTTVIPNSLML-GYAASKMLTV-YNWGRVAMLYYYSDIKYCSGV---MNDVEATFNNPSTPNVNI--VIKAEIYLNDNETTDIVFQS-VKSRARIIFW
||.. ..|..... |.|.....   ..| .||..|. .| .|. |.   |.... ... .  ..|..  | . . . .| .. . . .  .|..||.|..
PYFFRTVPSDTYQYGWAMVDIIQHHFGWKWVAVIYDDDDYYYWRGGCYFMEAFQDELREHGGNCVYYAYVSMVIPWDDDFMDYLKKIKDIIKMKARVIVM

CTQTAIE---KRDYLIKIATHDMIGDEYVHIMLSMRNIAFGAQTSLGKPTFSQSGLTPIWESFTEGTDDFEKMVKQAATRMFVLDVNSEVADKKYLDYLQ
|.. .     .| ...... . | ...||.|. .. . ... | .                      || ...  ..|  ... .    . .... ...|
CCYPDDMGLLQRQIMQQAHELGMMSGGYVWIYTDWWMHSYDMQ-W-------------------WYDDDMDNDKFREAMKGVLGFTMH-P-SPEFQEFMQ

KNIMKAVQSPPMNCSTVECMTANTTIMGGYARQLFDVVYLYGVALTNTNSTDPAVYDDV---------DVIVPQFV-TSFQGMTGKVVISPNLTRMPIFQ
.. .                  ..| | .|| ...| ||||. || |....||.....          ...      ..|.|.|| |..  |  |.| ..
RWKK------------------TDTEMNYYAAYAYDAVYLYAHALHNMLRCDPNHWNGGCDIMKWHGWQLLHYMWNKVNFEGVTGDVQFDDNGGRRPDYM

LYGLNSD
.. .| |
YWIMNWD

Kinase gcy-2.AA RGC 587-770 30 9.7e-92 311.09 In-house 1-239 (300) Show / Hide
Range on Protein: 587-770
Range on HMM: 1-239/300
Sequence Identity: 30% (73 aa)

EKEMVLTAKYQYT----HLTK--ADKERFVKMRKLDHENINRFIGLSIDSA------HFIAVTKLCSRGSLQDILSRGNFSMDYFFMFCIIRDVAKGLEY
|...|.. |....    |..   ...  . .||.|.|.|.|.|||..||.       ... |...||||||||||......|| .|... |||..||..|
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHKTFLRLHGNLRSATCLVNDSWQVKLAEYGMD----------------------NLV-EEQTPPKKRLLWVAPEVLRGSLSVSQME---------PSAD
||. ..| ||||.|..|.|...|.||.. .|.                       ..  ....| .|..|| |||.||.... .|..         ...|
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

IYSFAIIASEILTKKEAWDIL-----------DRKEDCE
.|||.||..||.|.|..||.            ...|. |
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIE

Kinase gcy-2.AA RGC 587-770 30 9.7e-92 311.09 In-house 1-239 (300) Show / Hide
Range on Protein: 587-770
Range on HMM: 1-239/300
Sequence Identity: 30% (73 aa)

EKEMVLTAKYQYT----HLTK--ADKERFVKMRKLDHENINRFIGLSIDSA------HFIAVTKLCSRGSLQDILSRGNFSMDYFFMFCIIRDVAKGLEY
|...|.. |....    |..   ...  . .||.|.|.|.|.|||..||.       ... |...||||||||||......|| .|... |||..||..|
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHKTFLRLHGNLRSATCLVNDSWQVKLAEYGMD----------------------NLV-EEQTPPKKRLLWVAPEVLRGSLSVSQME---------PSAD
||. ..| ||||.|..|.|...|.||.. .|.                       ..  ....| .|..|| |||.||.... .|..         ...|
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

IYSFAIIASEILTKKEAWDIL-----------DRKEDCE
.|||.||..||.|.|..||.            ...|. |
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIE

Kinase gcy-2.AA TKL 606-797 18 2.4e-29 102.81 In-house 72-364 (364) Show / Hide
Range on Protein: 606-797
Range on HMM: 72-364/364
Sequence Identity: 18% (56 aa)

KERFV-KMRKLDHENINRFIGLSIDSAH-------------FIAVTKLCSRGSLQDILSRGNFSMDYFFMFCIIRDVAKGLEYLHKTFL-------RLHG
.|. .  |..|.|.|| .|.| .... .             .  |. .|..||| ..|           .. ...|.|.|..|||            .| 
EEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHR

NLRSATCLVNDSWQ--------------VKLAEYGMDNLVEEQTP-----------------------PKKRLLWVAPEVLRGSLSVSQME---------
.| |. .||.. |.              .|.. .|    ... .                        .   . | |||||||..  ..           
DLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGF

---PSADIYSFAIIASEILTKKEAWD-----------------ILDRK--------------------EDC-EALIALVKDCWAEVPEDRPTAENICSQM
   ...|.|||.|.  |||| .. ..                 ... .                    .|| . .. | .|||.. ||.||... | ...
EYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL





Kinase gcy-2.AA TKL-Unique 612-757 25 1.5e-20 69.28 In-house 49-225 (290) Show / Hide
Range on Protein: 612-757
Range on HMM: 49-225/290
Sequence Identity: 25% (46 aa)

MRKLD-HENINRFIGLSI----DSAHFIAVTKLCSRGSLQDILS---------RGNFSMDYFFMFCIIRDVAKGLEYLHKTFL-RLHGNLRSATCLVNDS
| ||. |.|| ...| ..    . .... |.  |..||| | |.         . |  ...  .  ...|.|.|..||| .    .|..|.|   ||.  
MKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNN

-----WQVKLAEYGMDNLVE-EQTPPKKRL------------LWVAPEVLRGSLSVSQMEPSADIYSFAIIASEILTKK
     |..|..  |   .   . . .....            .|.||||||..   .|   ..|.|||.|.  ||.| |
SNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNF--CQYSEKSDVYSFGIVLWEIATRK

Kinase gcy-2.AA RGC 771-799 46 1.1e-13 44.58 In-house 271-300 (300) Show / Hide
Range on Protein: 771-799
Range on HMM: 271-300/300
Sequence Identity: 46% (14 aa)

ALIALVKDCWAEVPEDRPT-AENICSQMKG
.|..|..||||| ||.||. ...|..|.|.
CLLHLMRDCWAEDPEERPDMFDQIRKQLKT

Kinase gcy-2.AA RGC 771-799 46 1.4e-13 44.58 In-house 271-300 (300) Show / Hide
Range on Protein: 771-799
Range on HMM: 271-300/300
Sequence Identity: 46% (14 aa)

ALIALVKDCWAEVPEDRPT-AENICSQMKG
.|..|..||||| ||.||. ...|..|.|.
CLLHLMRDCWAEDPEERPDMFDQIRKQLKT

Kinase gcy-2.AA DRK 612-755 33 2.3e-13 41.68 In-house 51-197 (258) Show / Hide
Range on Protein: 612-755
Range on HMM: 51-197/258
Sequence Identity: 33% (51 aa)

MRKLDHENINRFIGLSIDSAHFIAVTKLCSRGSLQDILSRGNFSMDYFFMFCIIRDVAKGLEYLH-KTFLRLHGNLRSATCLVNDSWQVKLAEYGMDN--
| .| | ||  |.|    .     ..   .||||  ||     .||   |  .  |.|||. |||  .   .|  | |   || ..|||| | .|     
MCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRF

-LVEEQTPPKKRL---LWVAPEVLRGSLSVSQMEPSADIYSFAIIASEILT
  .....  .       |.||||||   .    |  ||.|||||.  |..|
KKHKQHKFAMTMCGTPCWTAPEVLR---NQRYTE-KADVYSFAIVLWECVT

S_TKc gcy-2.AA S_TKc 558-798 16 3.7e-10 -28.01 SMART 1-231 (231) Show / Hide
Range on Protein: 558-798
Range on HMM: 1-231/231
Sequence Identity: 16% (42 aa)

LQSAPSISTGHSGVTTVSDFCENYTMMMYEKEMVLTAKYQYTHLTKADKERFVKMRKLDHENINRFIGLSIDSAHFIAVTKLCSR--GSLQDILSRGNFS
 .    |  |  |.       .           .   |       .. .|. . ..  .|.|| ....   |  |.  |. .|.   |.| |.. . .  
YEILRKIGKGAFGKVYKCRHKK--------TGRIVAIKIIK---EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----MDYFFMFCIIRDVAKGLEYLHKTFLRLHGNLRSATCLVNDSWQVKLAEYGMDNLVEEQTPPKKRLLWVAPEVLRGSLSVSQMEP-SADIYSFAII
     ..     .... ....|||.|.    .|  |  .  |...  ..|..  |.  ..   |     . ..|||||       .  . ..|..|. .|
GLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCI

ASEILTKKEAWD----ILDRKEDCEALIALVKDCWAEVPEDRPTAENICS--------QMK
  | |. .  ..    ....    . .. ... |.   ||.||||  .          .  
LYEMLCGYPPFPQMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase gcy-2.AA TK 611-706 13 9.3e-10 28.09 In-house 93-297 (486) Show / Hide
Range on Protein: 611-706
Range on HMM: 93-297/486
Sequence Identity: 13% (28 aa)

KMRK---LDHENINRFIGLSIDS------------AHFIAVTKLCSRGS----LQDILS--RGNFS----------------------------------
|| .   ..|.|| |..| . ..             ... |. ... |.    |.| |   |..|.                                  
KMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNS

---------------------------------------MDYFFMFCIIRDVAKGLEYLHKTFLR-----LHGNLRSATCLVNDSWQ-----------VK
                                       ..   .  . ...|.|.||||.   .      |..|    |||... .           .|
PCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCK

LAEYGM
.| .|.
IADFGL

TyrKc gcy-2.AA TyrKc 583-797 18 2.4e-09 -71.45 SMART 1-280 (280) Show / Hide
Range on Protein: 583-797
Range on HMM: 1-280/280
Sequence Identity: 18% (55 aa)

MMMYE---------------------KEMVLTAKYQYTHLTKADKERFVK----MRKL--DHENINRFIGLSIDS-------AHFIAVTKLCSRGSLQDI
  . .                     | .   |           .| | .    |.||  .|.|| |..|  ...            |. ... |.|.| 
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

L--SRGNFSMDYFFMFCIIRDVAKGLEYLHKTFLRLHGNLRSATCLVNDSWQVKLAEYGM--DNLVE-------EQTPP----KKR----LLWVAPEVLR
|  .|....|. .  ||.  ..|.| ||||.  .  |  |    |||..  .|| .  |.  |   .       .   .     ..    . | |||...
LRKHRPKLCMKDLLSFCW--QIACGMEYLHSKNC-IHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

GS------------------LSVSQMEPSADIYSFAIIASEILTKKEAWDILDRKED--------C-EALIALVKDCWAEVPEDRPTAENICSQM
 .                  ..  |. .. .|    . ..|.. . .. . ... ..        | ...  . |.||.| |||||| ..|....
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase gcy-2.AA TESK 612-693 31 1.1e-08 23.04 In-house 47-127 (292) Show / Hide
Range on Protein: 612-693
Range on HMM: 47-127/292
Sequence Identity: 31% (26 aa)

MRKLDHENINRFIGLSIDSAHFIAVTKLCSRGSLQDILSRGNFSMDYFFMFCIIRDVAKGLEYLHKTFLRLHGNLRSATCLV
| || | || || |  .   .  |.|   . |.| ..|.  .  .          |.|.|. |||.     |  | |. |||
MNKLQHPNILRFMGVCVHQGQLHALTEYINGGCLEQLLADSELHLSWTQKIHLAYDIARGMSYLHSKGV-FHRDLTSKNCLV

Kinase gcy-2.AA TK 763-797 20 3.3e-08 22.82 In-house 437-486 (486) Show / Hide
Range on Protein: 763-797
Range on HMM: 437-486/486
Sequence Identity: 20% (10 aa)

LDRKEDCE--------------ALIAL-VKDCWAEVPEDRPTAENICSQM
. . ..|               .....  ..||.. |||||| . . .|.
MPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase gcy-2.AA UTK 612-706 23 2.5e-07 21.15 In-house 63-174 (296) Show / Hide
Range on Protein: 612-706
Range on HMM: 63-174/296
Sequence Identity: 23% (27 aa)

MRKLD-HENINRFIGLSIDSAHFIAVTKLCSRGSLQDILSRGNFSMD----YFF---MFCIIRDVAKGLEYLHKTFLRLHGNLRSATCLVNDS-------
| ... |.|. |..|.  ..  .. || ....|.|.. | |   . .    ..    . |  .|.| |..|||   .  |..|    |||...       
MKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGF-VHRDLAARNCLVHMHRMMWHCM

WQVKLAEYG---M
...|.| .|   |
MVCKIADFGRGGM

Kinase gcy-2.AA MLK 613-677 25 2.8e-07 21.47 In-house 60-142 (291) Show / Hide
Range on Protein: 613-677
Range on HMM: 60-142/291
Sequence Identity: 25% (21 aa)

RKLDHEN----INRFIGLSIDS-AHFIAVTKLCSRGSLQDILSRGN-------------FSMDYFFMFCIIRDVAKGLEYLHK
|.|.|.|    | .| | ....  ||  |.  |. ||| ..|  ..             . .|  ... .  ..|.|..|||.
RILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHS

Kinase gcy-2.AA Pkinase 612-677 28 4.7e-07 26.03 Pfam 54-126 (293) Show / Hide
Range on Protein: 612-677
Range on HMM: 54-126/293
Sequence Identity: 28% (21 aa)

MRKLDHENINRFIGLSIDSAHFIAVTKLCSRG----SLQDILS---RGNFSMDYFFMFCIIRDVAKGLEYLHK
|..|.|.|| |...   |. |   |. .|  |    .| |..|   .|.|....    .... ...||||.|.
MKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS

Kinase gcy-2.AA Pkinase 722-797 17 9.1e-07 25.01 Pfam 177-293 (293) Show / Hide
Range on Protein: 722-797
Range on HMM: 177-293/293
Sequence Identity: 17% (21 aa)

WVAPEVLRGSLSVSQMEPSADIYSFAIIASEILTKKEAWDIL-----------DRKEDC-------------------------------EALIALVKDC
..||||.|   . .   |..|..|. .|  | |...  ..              ..  .                               |... ..|.|
YMAPEVIR---GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC

WAEVPEDRPTAENICSQ--M
..  |..||||| |.    .
LCKDPKKRPTAEQILQHPWF

Kinase gcy-2.AA UTK 775-797 39 5e-06 16.49 In-house 274-296 (296) Show / Hide
Range on Protein: 775-797
Range on HMM: 274-296/296
Sequence Identity: 39% (9 aa)

LVKDCWAEVPEDRPTAENICSQM
|...||.  |..||..| . .||
LMHRCWHYDPQERPDFEDLVQQM

Kinase gcy-2.AA Pkinase_Tyr 612-676 25 6e-06 20.88 Pfam 57-128 (270) Show / Hide
Range on Protein: 612-676
Range on HMM: 57-128/270
Sequence Identity: 25% (18 aa)

MRKL-DHENINRFIGLSI-DSAH--FIAVTKLCSRGSLQDILSRG---NFSMDYFFMFCIIRDVAKGLEYLH
|..| .|.|| |..|  . .. .   . |. ..  |.| | | .    . . .   . .. ...|||.|||.
MKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLE

Kinase gcy-2.AA Dicty5 616-705 26 1.1e-05 15.53 In-house 56-149 (260) Show / Hide
Range on Protein: 616-705
Range on HMM: 56-149/260
Sequence Identity: 26% (25 aa)

DHENINRFIGLSIDSAHF-IAVTKLCSRGSLQDILSRGNF----SMDYFFMFCIIRDVAKGLEYLHKTFLRLHGNLRSATCLVNDSWQVKLAEYG
|| |. |. |           || .|..||| . |          . ||    .  |.|.....||      |  | |   |..  |..|.  .|
DHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMNI-IHRDLKSMNFLITENWKIKIIDFG

Kinase gcy-2.AA MLK 775-797 34 0.00011 12.32 In-house 269-291 (291) Show / Hide
Range on Protein: 775-797
Range on HMM: 269-291/291
Sequence Identity: 34% (8 aa)

LVKDCWAEVPEDRPTAENICSQM
| |.|| . |..||.   | .. 
LMKQCWNQDPHKRPSFRQIVQHL

Kinase gcy-2.AA DRK 773-799 33 0.000121 11.69 In-house 232-258 (258) Show / Hide
Range on Protein: 773-799
Range on HMM: 232-258/258
Sequence Identity: 33% (9 aa)

IALVKDCWAEVPEDRPTAENICSQMKG
|.| .||| | |  ||. . .   .  
IQLMNDCWNEDPQHRPSMQECLERLEA

Kinase gcy-2.AA Pkinase_Tyr 777-797 52 0.000165 15.89 Pfam 250-270 (270) Show / Hide
Range on Protein: 777-797
Range on HMM: 250-270/270
Sequence Identity: 52% (11 aa)

KDCWAEVPEDRPTAENICSQM
|.||.. |||||| . | .|.
KQCWHYDPEDRPTFSEIHEQL

Kinase gcy-2.AA TESK 722-753 46 0.000206 9.35 In-house 202-229 (292) Show / Hide
Range on Protein: 722-753
Range on HMM: 202-229/292
Sequence Identity: 46% (15 aa)

WVAPEVLRGSLSVSQMEPSADIYSFAIIASEI
|.||||||| .   .    ||..|| |.  ||
WMAPEVLRGEWYDEK----ADVFSFGIVLCEI

Kinase gcy-2.AA Dicty5 775-801 33 0.000248 10.81 In-house 234-260 (260) Show / Hide
Range on Protein: 775-801
Range on HMM: 234-260/260
Sequence Identity: 33% (9 aa)

LVKDCWAEVPEDRPTAENICSQMKGLV
|.| || . |  ||.   ||  .. ..
LIKKCWQQKPHNRPSFKEICKYFESII

Kinase gcy-2.AA Dicty5 741-761 47 0.000798 9.04 In-house 184-204 (260) Show / Hide
Range on Protein: 741-761
Range on HMM: 184-204/260
Sequence Identity: 47% (10 aa)

ADIYSFAIIASEILTKKEAWD
.|.|||.|.  |..|.||. |
CDVYSFGIVLWEMFTRKEPYD

Kinase gcy-2.AA TKL-Unique 775-797 30 0.00317 7.44 In-house 268-290 (290) Show / Hide
Range on Protein: 775-797
Range on HMM: 268-290/290
Sequence Identity: 30% (7 aa)

LVKDCWAEVPEDRPTAENICSQM
| ..||.  |..||. ..| .  
LIQQCWHHDPSQRPSFDEIIHRL

Kinase gcy-2.AA MLK 722-758 26 0.003462 7.06 In-house 199-234 (291) Show / Hide
Range on Protein: 722-758
Range on HMM: 199-234/291
Sequence Identity: 26% (10 aa)

WVAPEVL-RGSLSVSQMEPSADIYSFAIIASEILTKKE
| ||||. .  .  ..   ..|..|....  |.||...
WMAPEVIQQ--FRCEKYSEKCDVWSWGVVLWEMLTREV

CYCc gcy-2.AA CYCc 836-1032 41 6.4e-103 349.13 SMART 1-231 (231) Show / Hide
Range on Protein: 836-1032
Range on HMM: 1-231/231
Sequence Identity: 41% (96 aa)

LEKKKADILLSRMLPKQVAERLKAGQ-TVEPEGFDSVTVFFSDVVKFTILASKCSPFQTVNLLNDLYSNFDTIIEQHG-----VYKVESIGDGYLCVSGL
 ||.|.| || .|||. ||..||.|. .|.|. .|.||. |.|.| || |.|.|.|.|.||.|||.|..||.||..||     .|||| |||.| .|||.
MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC

PTRNG-------------------YAHIKQIVDMSLKFMEYCRSFKIPHL----PRENVELRIGVNSGPCVAGVVGLSMPRYCLFGDTVNTASRMESNGK
||||.                   ..|...|.|..|. .| ...|...|     | ... .|||...||.|.||||. |||||.||||||.||||||.|.
PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD

PSLIHLTSDAHLLL-----LTHYPNHYDTSS
|  ||........|      .. ....... 
PGQIHVSEETYWCLCLDQFERRRCGQFEFEP

Guanylate_cyc gcy-2.AA Guanylate_cyc 863-1051 42 1.2e-98 338.85 Pfam 1-214 (214) Show / Hide
Range on Protein: 863-1051
Range on HMM: 1-214/214
Sequence Identity: 42% (92 aa)

VEPEGFDSVTVFFSDVVKFTILASKCS----PFQTVNLLNDLYSNFDTIIEQH--GVYKVESIGDGYLCVSGLPTR-----NGYAHIKQIVDMSLKFMEY
|... .|.||..|.|.| || ..|.||    |.| |..|||.|..||....||  |.|||. ||| |.|||||| .     ....|. ...||.|..|||
VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY

CRSFKIPHLPREN-----VELRIGVNSGPCVAGVVG--LSMPRYCLFGDTVNTASRMESNGKPS--LIHLTSDAHLLLLTHYPNHYDT--SSRGEVIIKG
|... ..|..||.     ...|||...||.||||.|  ..|||||..|||||.||||||.|.|.   ||..  .. .| .|..  ...  ..|||. .||
CQQVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGVPGSCKIHVSEETYRCLKCHENFQFECHLQHRGEIPVKG

KGV---METFWVHG
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KGKMGEMETYFLHG

HNOBA gcy-2.AA HNOBA 823-857 51 5e-07 26.97 Pfam 200-234 (234) Show / Hide
Range on Protein: 823-857
Range on HMM: 200-234/234
Sequence Identity: 51% (18 aa)

LEEEIEERTKELTLEKKKADILLSRMLPKQVAERL
| ...|. ..||  |||| | ||  |.||.||.||
LKDKLEQMHRELEEEKKKTDDLLYSMFPKSVANRL