Gene gcy-21 (Nematode worm)

gcy-21

Species: Nematode worm
Alias: F22E5.3, CE09555, aSWK290, gcy-21
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: II: 2659669-2665021, WormBase Genetic Map location: n/a,

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
gcy-21.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 251 Kinase domain by global Sugen HMM Fasta, JSON
gcy-21.AA Protein Genbank 1119 None Fasta, JSON

Protein domain

Protein domains of gcy-21.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase gcy-21.AA RGC 515-767 32 8.20000000001e-111 374.45 In-house 1-300 (300) Show / Hide 
Range on Protein: 515-767
Range on HMM: 1-300/300
Sequence Identity: 32% (98 aa)

EGRTVALKRIYRS----DVEFTRSIRLEIAKLQESVNSNVIEFVGMVVQSP------DVFVVYELAQRGSLKDILDNDDMPLDDVFRSQMTKDIIAGLEY
||..|..|.. ..    ...||||.. |. .... .. |.. |.||.. .|      ....| |.  ||||.||| |||...|. |.. . .||. |..|
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHSSPIGCHGRLKSTNCLIDARWMVRLSSFGL-----RELRGEET----------WQQ-EDDVQEGKDQLWTSPELLRWSTGLSQCG-----VLLVQKSD
||.|||..||.|||.||..|.||.| .. |||     .... ...          ||. .|.  . |..|||.||.||...  .|.|     ..  || |
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

VYSLAIVLYELFGRLG-----PWGDE----PMEPREIVSLVKREALAGK-KPFRPDMAVLK-----ESPRIVQETVVAAWTEDPLNRPS-LHQIKRKLKP
|||..|..||...| |     |....     ..|.||.  ||.. . |  |||||..   .     | .  . . . . |.||| .||. ..||. .|| 
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-21.AA RGC 515-767 32 8.20000000001e-111 374.45 In-house 1-300 (300) Show / Hide 
Range on Protein: 515-767
Range on HMM: 1-300/300
Sequence Identity: 32% (98 aa)

EGRTVALKRIYRS----DVEFTRSIRLEIAKLQESVNSNVIEFVGMVVQSP------DVFVVYELAQRGSLKDILDNDDMPLDDVFRSQMTKDIIAGLEY
||..|..|.. ..    ...||||.. |. .... .. |.. |.||.. .|      ....| |.  ||||.||| |||...|. |.. . .||. |..|
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHSSPIGCHGRLKSTNCLIDARWMVRLSSFGL-----RELRGEET----------WQQ-EDDVQEGKDQLWTSPELLRWSTGLSQCG-----VLLVQKSD
||.|||..||.|||.||..|.||.| .. |||     .... ...          ||. .|.  . |..|||.||.||...  .|.|     ..  || |
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

VYSLAIVLYELFGRLG-----PWGDE----PMEPREIVSLVKREALAGK-KPFRPDMAVLK-----ESPRIVQETVVAAWTEDPLNRPS-LHQIKRKLKP
|||..|..||...| |     |....     ..|.||.  ||.. . |  |||||..   .     | .  . . . . |.||| .||. ..||. .|| 
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-21.AA TKL 512-765 18 1.4e-25 89.09 In-house 12-364 (364) Show / Hide 
Range on Protein: 512-765
Range on HMM: 12-364/364
Sequence Identity: 18% (68 aa)

GLYEG----------RTVALKRIYRSDVEF--------------------------TRSIRLEIAKLQESV-NSNVIEFVGMVVQSPD------------
| . |          ..|| |.. . .. .                           |  . | ...  .    |.. |.| . ..|.            
GKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWG

-VFVVYELAQRGS-LKDILDNDDMPLDDVFRSQMTKDIIAGLEYLHS-------SPIGCHGRLKSTNCLIDARWM--------------VRLSSFGLREL
  . |.|....|| | ...           | .. .||  |..||||        |   |  ||| |.|.|  |               . .. |||   
QLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRF

RGEETWQQEDDVQ----------------EGKDQLWTSPELLRWSTGLSQC--------GVLLVQKSDVYSLAIVLYELFGRLGPWGDEPMEPREIV---
  ... ..                     ..    | .||.|| .. ....        |    .|.|||| .|||.|.. |  |. |.|..|...    
MSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPF

-SLVKREALAGKKPFRPDMAVL-------KESPRIVQETVVAAWTEDPLNRPSLHQIKRKL
    .  .. |..| .|.           .  |. . .     | .|| .|||  .|. .|
EEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase gcy-21.AA TKL-Unique 549-695 28 3.4e-17 57.31 In-house 57-222 (290) Show / Hide 
Range on Protein: 549-695
Range on HMM: 57-222/290
Sequence Identity: 28% (49 aa)

NVIEFVGMVV----QSPDVFVVYELAQRGSLKDILD---------NDDMPLDDVFRSQMTKDIIAGLEYLHSSP--IGCHGRLKSTNCLIDAR-----WM
|.  ..|  .    . |. . | |  ..||| | |.         |. ..|.   | .| .||  |..|||..   |  |. |||.| |.| .     | 
NIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPI-IHRDLKSSNFLVDNNSNIAEWN

VRLSSFGLRELRGEE---TWQQE----DDVQEGKDQLWTSPELLRWSTGLSQCGVLLVQKSDVYSLAIVLYELF
.... |||. ..  .   |        ... .|   .| .||.|| .        .  .|||||| .|||.|..
IKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGS-FRWMAPEVLRMNF------CQYSEKSDVYSFGIVLWEIA
Kinase gcy-21.AA TK 549-765 14 8.1e-16 48.78 In-house 104-486 (486) Show / Hide 
Range on Protein: 549-765
Range on HMM: 104-486/486
Sequence Identity: 14% (55 aa)

NVIEFVGMVVQS------------PDVFVVYELAQRGS----LKDILDNDDMP-----------------------------------------------
|.. ..| ..|.            . . .| |... |.    |.| | . . .                                               
NIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDD

----------------------------LDDVFRSQMTKDIIAGLEYLHSSPI-----GCHGRLKSTNCLIDARWM-----------VRLSSFGLR----
                            |.   .  |  .| .|.||||| ..       |. |   |||.. .             .... |||     
LIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGS

--ELR----GEETWQQEDDVQEG------------------KDQL---WTSPELLRWSTGLSQC--GVLLVQKSDVYSLAIVLYELF--GRLGPWGDEPM
    |    ... . ...    .                  ...|   |..|| |. .   |..        ||||.|. ....|.|  |.  . |. . 
GVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLN-DRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSN

-------EPREIVSLVKRE--------------ALAGKKPFRPD------MAVLKESPRIVQETVVAAWTEDPLNRPSLHQIKRKL
       ...|.. ...|.                  . |  ||      .    . | ....     | .||  ||.  |....|
QDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMH-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase gcy-21.AA DRK 549-636 38 3.4e-14 44.52 In-house 58-146 (258) Show / Hide 
Range on Protein: 549-636
Range on HMM: 58-146/258
Sequence Identity: 38% (34 aa)

NVIEFVGMVVQSPDVFVVYELAQRGSLKDILDNDDMPLDDVFRSQMTKDIIAGLEYLHSS-PIGCHGRLKSTNCLIDARWMVRLSSFGL
|.. | |    .||. .. |   ||||  || .. . .|   . ||  |.  |. |||.. ||  |  ||| | |.|  | |  . |||
NICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGL
S_TKc gcy-21.AA S_TKc 503-769 17 3.7e-13 15.98 SMART 1-231 (231) Show / Hide 
Range on Protein: 503-769
Range on HMM: 1-231/231
Sequence Identity: 17% (51 aa)

WHQIPDFGVGLY----------EGRTVALKRIYRSDVEFTRSIRLEIAKLQESVNSNVIEFVGMVVQSPDVFVVYELAQR--GSLKDILDNDDMP-----
.. .   | | .           || ||.|.|        ..|| ||. |..    |.. . .. .   ....| |..    |.|.|....   .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LDDVFRSQMTKDIIAGLEYLHSSPIGCHGRLKSTNCLIDARWMVRLSSFGLRELRGEETWQQEDDVQEGKDQL----WTSPELLRWSTGLSQCGVLLVQK
..      ... |. .|||.||  | .|  ||  | |.|    . .. |||  .               . .     . .||.|               |
FPE-HARFYMYQICCALEYCHSHGI-IHRDLKPENILLDE--HIKICDFGLARQL--------------TTFCGTPWYMAPEVL----------GYGKCK

SDVYSLAIVLYELFGRLGPWGDEPMEPREIVSLVKREALAGKKPFRPDMAVLKESPRIVQETVVAAWTEDPLNRPSLHQIKR-----KLKPLT
.|..|. ..|||.. .  |.     .. ..  ...                    .. . . .   .. || .||.  .. .     |. |  
CDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase gcy-21.AA Dicty4-Unclassified 659-765 32 3.1e-12 38.19 In-house 174-263 (263) Show / Hide 
Range on Protein: 659-765
Range on HMM: 174-263/263
Sequence Identity: 32% (35 aa)

WTSPELLRWSTGLSQCGVLLVQKSDVYSLAIVLYELFGRLGPWGDEPMEPREIVSLVKREALAGKKPFRPDMAVLKESPRIVQETVVAAWTEDPLNRPSL
|.||| |.        .    ||||||| |..||||       ||||    || | .    .   |  || .      .  ..  ..  | .||  ||..
WESPECLM--------HESYNQKSDVYSYAMMLYELAT-----GDEPY--QEIQSIMNAARSVCDKKLRPKIP--DNCDNFWKKLIKWCWHNDPNKRPTM

HQIKRKL
 ||  .|
NQIIQYL
Kinase gcy-21.AA TESK 549-623 29 6.4e-12 33.48 In-house 54-127 (292) Show / Hide 
Range on Protein: 549-623
Range on HMM: 54-127/292
Sequence Identity: 29% (22 aa)

NVIEFVGMVVQSPDVFVVYELAQRGSLKDILDNDDMPLDDVFRSQMTKDIIAGLEYLHSSPIGCHGRLKSTNCLI
|.. | |  |.   .  . |    |.| ..|......|    . ..  ||  |. ||||  . .|  | | |||.
NILRFMGVCVHQGQLHALTEYINGGCLEQLLADSELHLSWTQKIHLAYDIARGMSYLHSKGV-FHRDLTSKNCLV
Kinase gcy-21.AA RAF 593-770 26 2.7e-11 32.57 In-house 107-282 (282) Show / Hide 
Range on Protein: 593-770
Range on HMM: 107-282/282
Sequence Identity: 26% (49 aa)

QMTKDIIAGLEYLHSSPIGCHGRLKSTNCLIDARWMVRLSSFGLRELRGEETWQQEDDVQEGKDQ-LWTSPELLR------WSTGLSQCGVLLVQKSDVY
.  . .  |..|||.  |  |  ||| | . .    |.   |||  ..  .. . .  ..      || .||  |          | |      ..||||
DISRQVCQGMDYLHAKNI-IHRDLKSNNIFLHEDMTVKIGDFGLMTVKTRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVLMQDENPYSFQSDVY

SLAIVLYELFGRLGPWGDEPMEPREIVSLVKREALAGKKPFRPDM-AVLKESPRIVQETVVAAWTEDPLNRPSLHQIKRKLKPLTI
|  ||.|||  |  | | .  .   |. ..      |..  |||. .|... |.  .. .   |  .. .||.  ||   || .|.
SFGIVMYELMTRHMPYGCHIWNRDQIIFMC------GRGYLRPDLSKVRQDCPKAMHRLMEDCWKFQREERPLFQQI---LKRITV
TyrKc gcy-21.AA TyrKc 509-765 22 8.3e-11 -47.89 SMART 12-280 (280) Show / Hide 
Range on Protein: 509-765
Range on HMM: 12-280/280
Sequence Identity: 22% (64 aa)

FGV---GLYEGRTVALKRIYRSDVEFTRSIRLEIAKLQES--VNSNVIEFVGMVVQS-------PDVFVVYELAQRGSLKDILDNDDMPLDDVFRSQMTK
||.   | .  ..|| | .  .     . .. |.  . .    . |.. ..| ..|.       . ...| |..  |.||| | .    |      ..  
FGEVYKGTWK-IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCW

DIIAGLEYLHSSPIGCHGRLKSTNCLIDARWMVRLSSFGL-RELRGEETW---QQEDDVQE--GKDQL----WTSPELLRWSTGLSQCGVLLV--QKSDV
.| .| ||||| ..  |  |   |||....  |. | ||| |..  . ..   ..  ...|  |.. .    |..|| .             .   ||||
QIACGMEYLHSKNC-IHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----------NYGKFTTKSDV

YSLAIVLYELF--GRLGPWGDEP--MEPREIVSLVKREALAGKKPFRPDMAVLKE-----SPRIVQETVVAAWTEDPLNRPSLHQIKRKL
.|  ....|.|  |   ..|..   |...|.. .||    .|. . .|. .   .      |  . .     | ||| .||.  .|....
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVK----QGYRMPQPPNDY--PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase gcy-21.AA Dicty4 549-636 28 4.5e-07 19.81 In-house 59-160 (277) Show / Hide 
Range on Protein: 549-636
Range on HMM: 59-160/277
Sequence Identity: 28% (29 aa)

NVIEFVGMVV----QSPDVFVVYELAQRGSLKDILDN------DDMPLD--DVFR-SQMTKDIIAGLEYLHS-SPIGCHGRLKSTNCLIDARWMVRLSSF
|.. | |       .....  | |.  .|.|  .| .      .  .||  .. |  .| .|.  |. .||.  |.  |  ||| | |.|. | |  . |
NICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDF

GL
||
GL
Kinase gcy-21.AA Dicty4 680-715 38 2.8e-05 13.73 In-house 196-231 (277) Show / Hide 
Range on Protein: 680-715
Range on HMM: 196-231/277
Sequence Identity: 38% (14 aa)

QKSDVYSLAIVLYELFGRLGPWGDEPMEPREIVSLV
.|.|||| .|||.|.. |  |   . |.. ..| .|
EKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAV
Kinase gcy-21.AA Pkinase 515-607 19 0.000654 14.91 Pfam 23-126 (293) Show / Hide 
Range on Protein: 515-607
Range on HMM: 23-126/293
Sequence Identity: 19% (20 aa)

EGRTVALKRIYRSDVEFTRSIRL----EIAKLQESVNSNVIEFVGMVVQSPDVFVVYELAQRG----SLKDILD-NDDMPL--DDVFRSQMTKDIIAGLE
.|..||.|.| ... .    ...    ||. ...    |.... ...  .... .| |... |    .|.|..   .. ..  ..     . . |. |||
TGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLE

YLHS
|.||
YCHS
Kinase gcy-21.AA DRK 681-700 60 0.000696 9.08 In-house 182-201 (258) Show / Hide 
Range on Protein: 681-700
Range on HMM: 182-201/258
Sequence Identity: 60% (12 aa)

KSDVYSLAIVLYELFGRLGP
| |||| |||| |.  |. |
KADVYSFAIVLWECVTRQDP
Kinase gcy-21.AA TKL-Unique 748-765 44 0.000896 9.4 In-house 273-290 (290) Show / Hide 
Range on Protein: 748-765
Range on HMM: 273-290/290
Sequence Identity: 44% (8 aa)

WTEDPLNRPSLHQIKRKL
|. || .|||. .|  .|
WHHDPSQRPSFDEIIHRL
Kinase gcy-21.AA Pkinase_Tyr 549-607 29 0.001073 13.14 Pfam 65-129 (270) Show / Hide 
Range on Protein: 549-607
Range on HMM: 65-129/270
Sequence Identity: 29% (19 aa)

NVIEFVGMVV-QSPD--VFVVYELAQRGSLKDILDND---DMPLDDVFRSQMTKDIIAGLEYLHS
|.. ..| .. |.    ...| |... |.|.| | .    . ||.     ||  .| .|.|||.|
NIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLES
Kinase gcy-21.AA Pkinase 680-765 14 0.004704 11.88 Pfam 191-293 (293) Show / Hide 
Range on Protein: 680-765
Range on HMM: 191-293/293
Sequence Identity: 14% (15 aa)

QKSDVYSLAIVLYELFGRLGPWGDE----PMEPREIVSLVKREALAGKKPFRPDMA------------VLKESPRIVQETVVAAWTEDPLNRPSLHQIKR
.|.|..|. ..|||.. .  |. ..    ........ ....  |    |   ..             . .. ..  .. .   .. ||  ||. .||. 
PKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQ

K--L
   .
HPWF
Kinase gcy-21.AA DRK 748-767 40 0.009434 5.19 In-house 239-258 (258) Show / Hide 
Range on Protein: 748-767
Range on HMM: 239-258/258
Sequence Identity: 40% (8 aa)

WTEDPLNRPSLHQIKRKLKP
| |||  |||. ..   |  
WNEDPQHRPSMQECLERLEA
Kinase gcy-21.AA Dicty4-Unclassified 597-636 32 0.017354 4.29 In-house 117-155 (263) Show / Hide 
Range on Protein: 597-636
Range on HMM: 117-155/263
Sequence Identity: 32% (13 aa)

DIIAGLEYLHSSPIGCHGRLKSTNCLIDARWMVRLSSFGL
||  |. .||.  .  |  .|| | |.|    ..   ||.
DIAQGMQHLHTRNF-IHRDIKSSNILMDKHFNIKIADFGI
Kinase gcy-21.AA Pkinase_Tyr 748-765 38 0.042475 7.73 Pfam 253-270 (270) Show / Hide 
Range on Protein: 748-765
Range on HMM: 253-270/270
Sequence Identity: 38% (7 aa)

WTEDPLNRPSLHQIKRKL
| .|| .||.  .| ..|
WHYDPEDRPTFSEIHEQL
Kinase gcy-21.AA Dicty4 748-767 36 0.082298 2.02 In-house 256-277 (277) Show / Hide 
Range on Protein: 748-767
Range on HMM: 256-277/277
Sequence Identity: 36% (8 aa)

WTEDPLNRPSLHQIKRK--LKP
| .|| .|||  .|  .  |  
WDHDPQHRPSFEEIIQRRILEH
Kinase gcy-21.AA Pkinase_Tyr 681-695 46 0.384413 4.49 Pfam 194-208 (270) Show / Hide 
Range on Protein: 681-695
Range on HMM: 194-208/270
Sequence Identity: 46% (7 aa)

KSDVYSLAIVLYELF
||||.|  ....|.|
KSDVWSFGVLMWEIF
CYCc gcy-21.AA CYCc 804-998 39 4.5e-90 306.47 SMART 1-231 (231) Show / Hide 
Range on Protein: 804-998
Range on HMM: 1-231/231
Sequence Identity: 39% (91 aa)

GEKAKSEALLKMMLPEVVADSLKLGS-NVSAESFENCTVFFSDCPGFVEMSATSKPIDIVQFLNDLYTVFDRIIDQFD-----VYKVETIADAYMVASGL
 || | . || .|||. ||..|| |   | .......|. |.| .|| ...... |...| .|||.|| ||||||...     .|||||| |||||.||.
MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC

PVPNG-------------------NHHAGEIASLGLALLKAVESFKIRHL----PNEKVRLRIGMNSGPCVAGVVGLKMPRYCLFGDTVNTASRMESNGI
| .|.                     || .||. .|  ......|...|     |....|.|||...||.|.||||..|||||.||||||.||||||.| 
PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD

PLRINCSGTAKEIL-------DQLGGYEIEE
| .|..| .....|          |..|.|.
PGQIHVSEETYWCLCLDQFERRRCGQFEFEP
Guanylate_cyc gcy-21.AA Guanylate_cyc 831-1017 38 6.1e-85 293.29 Pfam 1-214 (214) Show / Hide 
Range on Protein: 831-1017
Range on HMM: 1-214/214
Sequence Identity: 38% (82 aa)

VSAESFENCTVFFSDCPGFVEMSATSK----PIDIVQFLNDLYTVFDRIIDQF--DVYKVETIADAYMVASGLPVP-----NGNHHAGEIASLGLALLKA
| |......|..|.| .|| .... .     |. .|..|||.|| |||..||.  ..|||.|| |.||..||||.|     .. |||  .|  .|.....
VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY

VESFKIRHLPNEK-----VRLRIGMNSGPCVAGVVG--LKMPRYCLFGDTVNTASRMESNGIPL--RINCSGTAKEILDQLGGYEIE----ERGIVEMKG
.... . |.. |      ...|||...||.||||.|  ..|||||..|||||.||||||.|.|.  .|. | .....| .......|    .||....||
CQQVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGVPGSCKIHVSEETYRCLKCHENFQFECHLQHRGEIPVKG

KGKQ---MTYFVRG
|||.    |||. |
KGKMGEMETYFLHG
HNOBA gcy-21.AA HNOBA 799-825 48 0.000139 18.14 Pfam 208-234 (234) Show / Hide 
Range on Protein: 799-825
Range on HMM: 208-234/234
Sequence Identity: 48% (13 aa)

NEELEGEKAKSEALLKMMLPEVVADSL
..||| || |...||  |.|  ||. |
HRELEEEKKKTDDLLYSMFPKSVANRL