Gene gcy-8 (Nematode worm)

gcy-8

Species: Nematode worm
Alias: gcy-8, aSWK297, CE20579, C49H3.1
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: IV: 7928148-7933700, WormBase Genetic Map location: n/a,

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
gcy-8.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 275 Kinase domain by global Sugen HMM Fasta, JSON
gcy-8.AA Protein Genbank 1206 None Fasta, JSON

Protein domain

Protein domains of gcy-8.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ANF_receptor gcy-8.AA ANF_receptor 82-468 20 2.8e-55 194.74 Pfam 1-364 (364) Show / Hide 
Range on Protein: 82-468
Range on HMM: 1-364/364
Sequence Identity: 20% (84 aa)

NDVKILEVSHKALQAEGI-LDDDLDVEIISQTGC--GESYEGVAVAADMYHLQKVKAFIGPYCNAEMDAVARMAAFWNIPIIGYMAASNNLAD--KNAYP
.    ..   . . |..  |. ....... .  |   ..  .||.|.. .| ..|.|.|||.| .....|||.|. ||||.|.. . .  | |  || ||
QCAPAMRMAIEDINADPGILLPGITLGYHDDDCCYCSDC-QAVAAADCCWH-KGVVAIIGPSCSYVCIPVARIANHWNIPMISWGCTCPCLTDKAKNRYP

TLARISAFIISKIHKYYFFFNFLDDRSKVGISLRTTNSIAEATCAMLRH-YGWNKVAIITNTGILAYDR-----VLSFEEVFHQRGINVVKK--IMFDEF
...|                          .  . |. ...|  ....| .||..||.| . .   |.|     .  |.......|.|.| .   .. . 
YFFR--------------------------TVPSDTYQYGWAMVDIIQHHFGWKWVAVIYDDDDYYYWRGGCYFMEAFQDELREHGGNCVYYAYVSMVIP

ADSKAMIASGLLND-IKNSARIVVCLFSNTRES--SREFLTAANTQGMNVNEYGYVFPWLQDGGKDASPWTGADGSMLQKVKDQYANAIIIDDVNSFDNT
 |...| ..  ..| || .||..|. .. .. .  .|... .|  .||.  .| ... ..  .. | . | ..|..|...   ......... .  . ..
WDDDFMDYLKKIKDIIKMKARVIVMCCYPDDMGLLQRQIMQQAHELGMMSGGYVWIYTDWWMHSYDMQ-W-WYDDDMDNDKFREAMKGVLGFTMH-P-SP

IVGPFIERIKDVGLTEADVDIANIYGYLYLFDALKLYAIAARKVLNETGKAENLL------NGRMMWQNMRK-LKFVGMVGASGIASGQVSMDDRAERAP
 .  |..|.|         |    |  .|..|| .||| |....|.... . | .      .|  . . |..  .|         ..|.|..||.  | |
EFQEFMQRWKK-------TDTEMNYYAAYAYDAVYLYAHALHNMLRCDPNHWNGGCDIMKWHGWQLLHYMWNKVNF-------EGVTGDVQFDDNGGRRP

LYRGFFVSPN
 |   .. ..
DYMYWIMNWD
Kinase gcy-8.AA RGC 666-909 36 4.1e-113 382.08 In-house 31-300 (300) Show / Hide 
Range on Protein: 666-909
Range on HMM: 31-300/300
Sequence Identity: 36% (100 aa)

QMKAAVHDNINPFLGMVWNEREE-----MLLVWKFCSRGTLQDIIYNESIQLDTKFHGAFIRDILAGLEYLHASQIGYHGSLTPWSCLIDRNWMIKLTDY
||. ..|||.|.|.||.... .|     |..||..||||.||||..|..|..| .|...|||||. |..|||.|.|.|||.|..|.|..|..|..|.||.
QMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQYLHHSPIRYHGNLKSWNCVVDSRWVVKITDF

GIADPLERWEKSQSISRDGLTSDDDKSQATQATSILYESPEMLKNREKNRVRRVDQDWM--RQTQTRRQLGDVYAFGLVMYEIIFRAL-----PFPE--G
|...||..|.|...|... .. .||||.  | ..  |..... .. | .| .| ...|   ||||...| ||||.|| .|||||.|       || .  |
GLNNPLCHWFKHGQINPP-CK-SDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGDVYSFGIIMYEIITRKGPWDLEPFCMWPG

TNQSELVEWLRD--------GSKVVKPTIPQNKV-----LNMDLSALIQDCWNTTPEMRPS-LRRIKLNVET
 . ... |....        |.|.  |.|. ..      .|..| .|..|||.  ||.||. ...|.....|
EYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-8.AA RGC 666-909 36 4.1e-113 382.08 In-house 31-300 (300) Show / Hide 
Range on Protein: 666-909
Range on HMM: 31-300/300
Sequence Identity: 36% (100 aa)

QMKAAVHDNINPFLGMVWNEREE-----MLLVWKFCSRGTLQDIIYNESIQLDTKFHGAFIRDILAGLEYLHASQIGYHGSLTPWSCLIDRNWMIKLTDY
||. ..|||.|.|.||.... .|     |..||..||||.||||..|..|..| .|...|||||. |..|||.|.|.|||.|..|.|..|..|..|.||.
QMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQYLHHSPIRYHGNLKSWNCVVDSRWVVKITDF

GIADPLERWEKSQSISRDGLTSDDDKSQATQATSILYESPEMLKNREKNRVRRVDQDWM--RQTQTRRQLGDVYAFGLVMYEIIFRAL-----PFPE--G
|...||..|.|...|... .. .||||.  | ..  |..... .. | .| .| ...|   ||||...| ||||.|| .|||||.|       || .  |
GLNNPLCHWFKHGQINPP-CK-SDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGDVYSFGIIMYEIITRKGPWDLEPFCMWPG

TNQSELVEWLRD--------GSKVVKPTIPQNKV-----LNMDLSALIQDCWNTTPEMRPS-LRRIKLNVET
 . ... |....        |.|.  |.|. ..      .|..| .|..|||.  ||.||. ...|.....|
EYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-8.AA TKL-Unique 688-907 23 2.1e-24 83.09 In-house 74-290 (290) Show / Hide 
Range on Protein: 688-907
Range on HMM: 74-290/290
Sequence Identity: 23% (58 aa)

EMLLVWKFCSRGTLQDIIY---------NESIQLDTKFHGAFIRDILAGLEYLHASQ--IGYHGSLTPWSCLIDRN-----WMIKLTDYGIADPLERWEK
.| .|  .|..|.| | .          |... |. .    ...||  |..||| ..  | .|. |.. . |.|.|     | ||. | |..  . .  |
NMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPI-IHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINK

SQSI----SRDGLTSDDDKSQATQATSILYESPEMLKNREKNRVRRVDQDWMRQTQTRRQLGDVYAFGLVMYEIIFRAL------PFPEGTNQSELVEWL
. ..    .|           .|  .|... .||.|.. .                .. .  |||.|| |..||. | .      |. .| .| .. | .
MTNNEHKGTR----------NQTRCGSFRWMAPEVLRMNF---------------CQYSEKSDVYSFGIVLWEIATRKITKTYKKPY-QGMDQEQWCEMV

RDGSKVVKPTIPQNKVLNMDLSALIQDCWNTTPEMRPSLRRIKLNV
..  .   |.||..  .. ... |||.||.  |. |||.  |    
HYMEENYRPPIPNH--CPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase gcy-8.AA TKL 656-907 18 5.7e-23 79.56 In-house 67-364 (364) Show / Hide 
Range on Protein: 656-907
Range on HMM: 67-364/364
Sequence Identity: 18% (59 aa)

KHLFYDRNHIQMKAAV-HDNINPFLGMVWNERE------------EMLLVWKFCSRGTLQDIIYNESIQLDTKFH--GAFIRDILAGLEYLHASQI----
.  |  .. | |.    |.|| .|.| . ...             .. .|  .|..|.| ...          .|    ...||  |..|||...     
WFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCT

---GYHGSLTPWSCLIDRNWM--------------IKLTDYGIADPLERWEKSQSISRDGL-----TSDDDKSQATQATSILYESPEMLKNREKNR----
     |  |..  .|.|.||               .|..|.|..  ... .... .. ..        . .|   ||  .. . .||.|.. ....    
KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQ-NNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVG

VRRVDQDWMRQTQTRRQLG----------DVYAFGLVMYEIIFRALPFPEGTNQSELVE------WLRDGSKVVKPTIP----------QNKVLNMDLSA
.               .            |||.||.|..||. | .|. .  . ....       .  ...|  .|.||          ...    ... 
I--------------DE-FCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKK

LIQDCWNTTPEMRPSLRRIKLNV
|.||||.. || |||  .|.   
LMQDCWDHDPEKRPSFQEILKRL
Kinase gcy-8.AA LRRK 830-909 28 1.7e-13 44.05 In-house 264-351 (351) Show / Hide 
Range on Protein: 830-909
Range on HMM: 264-351/351
Sequence Identity: 28% (25 aa)

DVYAFGLVMYEIIFRA-LPFPE--GTNQSELVEWLRD-GSKVVKPTIPQNKVLNM-----DLSALIQDCWNTTPEMRPSLRRIKLNVET
|.|.||....|.. |  .|| |  .  .... | ..|  ..  .|||||. . .      ....|||.||.. |. ||.   |    ..
DCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQH-YCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase gcy-8.AA RAF 672-909 22 5.2e-11 31.64 In-house 57-282 (282) Show / Hide 
Range on Protein: 672-909
Range on HMM: 57-282/282
Sequence Identity: 22% (56 aa)

HDNINPFLGMVWNER-EEMLLVWKFCSRGTLQDIIYNESI--QLDTKFHGAFIRDILAGLEYLHASQIGYHGSLTPWSCLIDRNWMIKLTDYGIADPLER
|.||  |.| . .   . .  | ..|   .|   |       ..|        | .  |..|||| .|  |  |     . .    .| .|.| .    |
HCNILLFMGYMSKPQTNTYAIVTQWCEHSSLYHHIHVQETREKFDMHWLIDISRQVCQGMDYLHAKNI-IHRDLKSNNIFLHEDMTVKIGDFGLMTVKTR

WE--KSQSISRDGLTSDDDKSQATQAT-SILYESPEMLKNREKNRVRRVDQDWMRQTQTRRQLGDVYAFGLVMYEIIFRALPFPEGTNQSELVEWLRDGS
|    .|              |. | | .||. .||  .|   .    |    |. .    .  |||.|| ||||.. | .|.    .. ... ..  | 
WSPRGNQ--------------QFEQPTHWILWMAPEVIRNLMIDWRGDV---LMQDENPYSFQSDVYSFGIVMYELMTRHMPYGCHIWNRDQIIFMC-GR

KVVKPTI-PQNKVLNMDLSALIQDCWNTTPEMRPSLRRIKLNVET
. ..| .  . .     .  |..|||  ..| ||. . |   .. 
GYLRPDLSKVRQDCPKAMHRLMEDCWKFQREERPLFQQILKRITV
Kinase gcy-8.AA TK 830-907 21 1.5e-10 30.8 In-house 376-486 (486) Show / Hide 
Range on Protein: 830-907
Range on HMM: 376-486/486
Sequence Identity: 21% (24 aa)

DVYAFGLVMYEIIFRA-LPFPEGTNQ---------SELVEWLRDGSK---------VVKPTIPQNKVLN--------------MDLSALIQDCWNTTPEM
||..|| .|.||  ..  |...| .           |..| ||.|..           .   || .                  ..  |.|.||.  || 
DVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPED

RPSLRRIKLNV
||. . ..   
RPTFSQLHEQL
S_TKc gcy-8.AA S_TKc 603-911 15 1.6e-10 -22.48 SMART 1-231 (231) Show / Hide 
Range on Protein: 603-911
Range on HMM: 1-231/231
Sequence Identity: 15% (49 aa)

SRNHAIVGTNTHAIYHKYVQRRPIVFNRADKTLIQLAKNFSQNPKEAGLPNYFKHLFYDRNHIQMKAAVHDNINPFLGMVWNEREEMLLVWKFCSR--GT
 . . ..|  . .  .| . ..      | | .                    .|.   ..  ..    |.||  ....  .  ... .|  .|.   |.
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK-------------------EHIRREIQILKK---HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGD

LQDIIYNESIQ-----LDTKFHGAFIRDILAGLEYLHASQIGYHGSLTPWSCLIDRNWMIKLTDYGIADPLERWEKSQSISRDGLTSDDDKSQATQATSI
| |.| .   .     ..      ... |. .|||.|  .|  |  | |   |.|.   ||..| |.|  |                       |.  . 
LFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGI-IHRDLKPENILLDE--HIKICDFGLARQL----------------------TTFCGTP

LYESPEMLKNREKNRVRRVDQDWMRQTQTRRQLGDVYAFGLVMYEIIFRALPFPEGTNQSELVEWLRDGSKVVKPTIPQNKVLNMDLSALIQDCWNTTPE
 | .||.|                   .  .   |....| ..|| . .  |||   .. .. . ..                  ..  .|. |..  ||
WYMAPEVL-------------------GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG----------------SPEAKDFIRKCLQKDPE

MRPSLRRIKL-----NVETYL
 ||.   .       .   ..
KRPTA-EALQDEWDIKCHPWF
Kinase gcy-8.AA Axl 830-905 28 4.2e-09 28.16 In-house 197-267 (267) Show / Hide 
Range on Protein: 830-905
Range on HMM: 197-267/267
Sequence Identity: 28% (22 aa)

DVYAFGLVMYEIIFRALPFPEGTNQSELVEWLRDGSKVVKPTIPQNKVLNMDLSALIQDCWNTTPEMRPSLRRIKL
||.|||  |.||. |      | . .|. ..|..| .. .|    .  .. .| .|.  ||.. |. |||   ...
DVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQP----EDCMD-ELYDLMYQCWEADPKDRPSFSVLRE
Kinase gcy-8.AA RAF 830-848 52 5.3e-07 20.02 In-house 199-217 (275) Show / Hide 
Range on Protein: 830-848
Range on HMM: 199-217/275
Sequence Identity: 52% (10 aa)

DVYAFGLVMYEIIFRALPF
|||||| |.||.. ...|.
DVYAFGTVWYELMAGEWPY
Kinase gcy-8.AA RAF 881-907 33 8.8e-07 19.27 In-house 249-275 (275) Show / Hide 
Range on Protein: 881-907
Range on HMM: 249-275/275
Sequence Identity: 33% (9 aa)

DLSALIQDCWNTTPEMRPSLRRIKLNV
... |...||...|| |||...|.   
EMKELLMECWSYQPEERPSFQQIMKMI
Kinase gcy-8.AA KSR 881-907 22 1e-06 18.45 In-house 246-272 (272) Show / Hide 
Range on Protein: 881-907
Range on HMM: 246-272/272
Sequence Identity: 22% (6 aa)

DLSALIQDCWNTTPEMRPSLRRIKLNV
... ... ||.. |. ||.. .|..  
EMKEILMMCWSYEPQERPTFQDIMKML
Kinase gcy-8.AA TyrKc 626-907 15 3e-06 -120.49 SMART 1-280 (280) Show / Hide 
Range on Protein: 626-907
Range on HMM: 1-280/280
Sequence Identity: 15% (51 aa)

IVFNR--------------ADKTLIQLAKNFSQNPKEAGLPNYFKHLFYDRNHIQMKAA--VHDNINPFLGMVWNER------EEMLLVWKFCSRGTLQD
|....              ..  .    |    .          .  |..   | |.     |.||  ..| .  .       | ...|  ... | |.|
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---------REDFMREARI-MCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

II-YNES-IQLDTKFHGAFIRDILAGLEYLHASQIGYHGSLTPWS----------CLIDRNWMIKLTDYGIADPLERW-EKSQSISRDGLTSDDDKSQAT
 . ...  ...... .  |  .| .| ||||                        ||...|  .| .| | .  ..   ..          |.| .....
YLRKHRPKLCMKDLLS--FCWQIACGMEYLHSK-----------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--------ESKDYYRKKE

--QATS---ILYESPEMLKNREKNRVRRVDQDWMRQTQTRRQLGDVYAFGLVMYEIIFRALPFPEG-----TNQSELVEWLRDGSKVVKPTIPQNKV---
  .. .   |   .|| .                 .. .     ||..|| .|.||  .  . ..|      . .|..|....|    .|  .   .   
HKGGKTMLPIRWMAPECI-----------------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFV

-LNMDLSALIQDCWNTTPEMRPSLRRIKLNV
    ..  ....||.  ||.||. . |.   
CCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase gcy-8.AA Pkinase_Tyr 830-907 27 1.6e-05 19.36 Pfam 196-270 (270) Show / Hide 
Range on Protein: 830-907
Range on HMM: 196-270/270
Sequence Identity: 27% (22 aa)

DVYAFGLVMYEIIFRA-LP-FPEGTNQSELVEWL-RDGSKVVKPTIPQNKVLNMDLSALIQDCWNTTPEMRPSLRRIKLNV
||..|| .|.||. .   | .|.    .|..|.. .||        |. .    ..  |...||.  ||.||. . |    
DVWSFGVLMWEIFTYGEQPTYPGM-SNEEVYEYIYEDGYR-----MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase gcy-8.AA RGC 611-641 17 3.1e-05 14.59 In-house 1-34 (300) Show / Hide 
Range on Protein: 611-641
Range on HMM: 1-34/300
Sequence Identity: 17% (6 aa)

TNTHAIYHKYVQR---RPIVFNRADKTLIQLAKN
........|..||   |.. |.|...... . ..
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQ
Kinase gcy-8.AA KSR 830-848 57 3.2e-05 13.77 In-house 198-216 (272) Show / Hide 
Range on Protein: 830-848
Range on HMM: 198-216/272
Sequence Identity: 57% (11 aa)

DVYAFGLVMYEIIFRALPF
|||||| . ||.| ...||
DVYAFGTIWYEMICGEWPF
Kinase gcy-8.AA RGC 611-641 17 3.4e-05 14.59 In-house 1-34 (300) Show / Hide 
Range on Protein: 611-641
Range on HMM: 1-34/300
Sequence Identity: 17% (6 aa)

TNTHAIYHKYVQR---RPIVFNRADKTLIQLAKN
........|..||   |.. |.|...... . ..
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQ
CYCc gcy-8.AA CYCc 945-1140 41 3.1e-105 356.85 SMART 1-231 (231) Show / Hide 
Range on Protein: 945-1140
Range on HMM: 1-231/231
Sequence Identity: 41% (97 aa)

EANQRADRLLSQLLPAYVANELKLGR-PVPPKTFTSSTVLFSDIVGFTEMCQNASPLEVVAVLNGIFDGFDQFIARKD-----AYKVETIGDAYMVVSGV
...|..|||| |.||..|||.|| || ||.|... . |.||.||||||..|. ..|..|| .||.... ||..|.| .     .|||||||||||||||.
MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC

PEENGH-------------------RHINEIASIALDVHKFLSEFIVPHK----RDTKVQCRLGFHTGPVAAAVVGLNAPRYCLFGDTVNMASRMESNSE
|..|.|                   .|. .||..||| .... .|.|.|.    .......| |.|||||.. |||. .||||.|||||||||||||...
PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD

PGKTQISETAKNLL------LKEYPDYICEQ
||....||.....|      ... ... .|.
PGQIHVSEETYWCLCLDQFERRRCGQFEFEP
Guanylate_cyc gcy-8.AA Guanylate_cyc 972-1159 38 8e-71 246.4 Pfam 1-214 (214) Show / Hide 
Range on Protein: 972-1159
Range on HMM: 1-214/214
Sequence Identity: 38% (83 aa)

VPPKTFTSSTVLFSDIVGFTEMCQNAS----PLEVVAVLNGIFDGFDQFIARK--DAYKVETIGDAYMVVSGVPEE-----NGHRHINEIASIALDVHKF
|... . . |..|.||||||..| . |    |...|  || ..  || .....  . |||.||||.||.|||.|..     ..  |.  .| .|||. ..
VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY

LSEFIVPHKRDTK-----VQCRLGFHTGPVAAAVVG--LNAPRYCLFGDTVNMASRMESNSEPG--KTQISETAKNLLLKEY-PDYIC--EQRGEIPIKG
.... |.|.  .      .| | | ||||| | |.|  .  ||||..|||||.||||||...||  | ..||... .| ... ... |  . |||||.||
CQQVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGVPGSCKIHVSEETYRCLKCHENFQFECHLQHRGEIPVKG

KGL---CMTYWLMG
||      ||.|.|
KGKMGEMETYFLHG
HNOBA gcy-8.AA HNOBA 919-966 34 0.000148 18.04 Pfam 190-234 (234) Show / Hide 
Range on Protein: 919-966
Range on HMM: 190-234/234
Sequence Identity: 34% (17 aa)

DQMTRMME-QYANNLEKLVAERTGMLEEANQRADRLLSQLLPAYVANEL
..... || |  ..||.  .|    |||  .. |.|| . .|. |||.|
YKLMCRMEQQLKDKLEQMHRE----LEEEKKKTDDLLYSMFPKSVANRL