H12I13.1

Species: Nematode worm
Alias: CE23804, H12I13.d, aSWK218, H12I13.1
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: II:-0.72, WormBase Physical Map location: II: 6064290-6062209,

Classification

Group: Other
Family: Haspin

Sequence

Name Sequence Type Origin Length Description Download
H12I13.1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 295 Kinase domain by global Sugen HMM Fasta, JSON
H12I13.1.AA Protein Genbank 592 None Fasta, JSON

Protein domain

Protein domains of H12I13.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
UCH H12I13.1.AA UCH 72-114 34 0.000131 12.69 Pfam 364-403 (403) Show / Hide
Range on Protein: 72-114
Range on HMM: 364-403/403
Sequence Identity: 34% (15 aa)

DAKDRRWEKMDDVHVSDVSWE-EVERHSYGTGSDDTSSAVLIVY
. |. .| | || ||..|. . ||.. ..|    |..|| . .|
HNKNNKWYKFDDDHVTRVTEWEEVLKENGG----DWWSAYMLFY

SPK H12I13.1.AA SPK 216-332 18 3.3e-23 84.34 SMART 1-118 (118) Show / Hide
Range on Protein: 216-332
Range on HMM: 1-118/118
Sequence Identity: 18% (23 aa)

YLNQCIKFLHTKSEN-VGKPFVRTTFYANFKNVVY----YKGTATTLGRGLQPLLHDAIISSEYKDFRKCQMLFVMSIQITNQSFLYRLAKN-SFSITLD
.|.....||..|... . . .|.|. .. |..        .. .|   |  ..| .  . ...| . ....|.|..|.... ..|| .. .. .  ..||
ELTRFMDFLVEKTKDAIEPMVVTTKVFKEFSKYENHVNGCRSYTTYYKRFHNKLAPNMHKWNNYSIEERIRMMFALSGKVE-DDFLEQIQTHHIGTVQLD

RFYRIEVCEYQSKKFSGVHKCPG
...||. .   .    | .|. |
EKRRICKYTSND----GKLKLEG

Kinase H12I13.1.AA Haspin 417-591 36 5.9e-80 271.93 In-house 1-216 (264) Show / Hide
Range on Protein: 417-591
Range on HMM: 1-216/264
Sequence Identity: 36% (79 aa)

LQRKIGFGAYGSAYSVKYGGKTVVMKLIGIR--DN-------------EQLLFNELIITQQLGKLAKNRVCPNFLEYCGSHVMTDVP-------VGMRRD
...|||.|.||...||.. ||.||||.|.|.  ..             .. ..||.||....|||.....||||...||..|.|.||       . |...
NCKKIGEGCYGEVFSVTWNGKEVVMKIIPIHWSCCKYYGEYCGEHQQTNDEALNEIIIMKKMGKLSHRNMCPNFPNFCGMCVVTQVPGKCCKKLNKMWDH

PKAIR---------------HLAILMARGGGVLDN--WKFKDYRQCVSVFCQLVMSLKVVKDSINMVHRDIHLWNVLVS-RTKTTCLDYSMDGK-VKLNS
.....               |....|..|| .|||  |||....||.|..||||||... ||.....|.|.|..|||.. .||...|.|.|||| .|..|
YCYTHHSENDRPDFFKKNQLHIHWIMEYGGRPLDNFRWKFNTCNQCISIMCQLVMSMYIAKDEMQFWHNDLHWGNVLIKRKTKKKWLHYTMDGKTIKIKS

YGVVMHLIDFSKSLYG
.||....|||.|| .|
HGVMVTIIDFCKSRCG

Kinase H12I13.1.AA HH498 415-442 39 5e-06 14.68 In-house 1-28 (284) Show / Hide
Range on Protein: 415-442
Range on HMM: 1-28/284
Sequence Identity: 39% (11 aa)

IELQRKIGFGAYGSAYSVKYGGKTVVMK
|| ..||| |..|  | ... .| |  |
IEFHEKIGSGSFGKVYKGEWRNKIVAVK

Kinase H12I13.1.AA MLK 415-444 26 2e-05 14.96 In-house 1-30 (291) Show / Hide
Range on Protein: 415-444
Range on HMM: 1-30/291
Sequence Identity: 26% (8 aa)

IELQRKIGFGAYGSAYSVKYGGKTVVMKLI
|.....|| |..|. .. .. .|..| | .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIV

Kinase H12I13.1.AA LISK 420-449 28 0.000232 9.85 In-house 1-32 (296) Show / Hide
Range on Protein: 420-449
Range on HMM: 1-32/296
Sequence Identity: 28% (9 aa)

KIGFGAYGSAYSVKYG--GKTVVMKLIGIRDN
.|| |..|..| . .   |. ...| | . .|
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPN

Kinase H12I13.1.AA RAF 415-443 27 0.000327 9.22 In-house 1-29 (282) Show / Hide
Range on Protein: 415-443
Range on HMM: 1-29/282
Sequence Identity: 27% (8 aa)

IELQRKIGFGAYGSAYSVKYGGKTVVMKL
.... .|| | .|. |. .. |.  | .|
VMVMTRIGSGSFGTVYRGHWHGDVAVKML

Kinase H12I13.1.AA FAK 540-556 64 0.003268 6.43 In-house 142-158 (285) Show / Hide
Range on Protein: 540-556
Range on HMM: 142-158/285
Sequence Identity: 64% (11 aa)

SINMVHRDIHLWNVLVS
|.. |||||   |||||
SKKFVHRDIAARNVLVS

Kinase H12I13.1.AA FAK 415-430 50 0.029469 3.18 In-house 1-16 (285) Show / Hide
Range on Protein: 415-430
Range on HMM: 1-16/285
Sequence Identity: 50% (8 aa)

IELQRKIGFGAYGSAY
|.| |.|| | .|  |
ITLNRCIGEGQFGDVY