Gene K11H12.9 (Nematode worm)

K11H12.9

Species: Nematode worm
Alias: K11H12.9, aSWK252, CE30095
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: IV: 649669-651798, WormBase Genetic Map location: IV:-22.79,

Classification

Group: Other
Family: Other-Unique

Sequence

Name Sequence Type Origin Length Description Download
K11H12.9.AA Protein Genbank 374 None Fasta, JSON
K11H12.9.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 228 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of K11H12.9.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase K11H12.9.AA Other-Unique 101-323 7 3.7e-22 72.32 In-house 1-249 (249) Show / Hide 
Range on Protein: 101-323
Range on HMM: 1-249/249
Sequence Identity: 7% (20 aa)

AIELNAGTSTRSTSISCSATDLLESDHVTIRKISLQDPATAR---------------------------REYRNIILCRLLPHPNILPISEAYEVDSTLY
 .... ||..|.    .  .. ....... .||  .   ...                           .|... ...... ...  .... . . ....
IKDIGKGTYGRVYKQHHNKKKKYCAKKTKHHKI-HCMDMDNNKREQIYHYQIIHCIFYWTMNHCHLCFCYEHCPNMIFYIMYPWY--HHHCECQCQCEHW

TVSEQMDGRLSDIVEERLTHFVVAKISHQILAAVAMMHQNG--------IAHGDLTLSTIYVNTDAELRLSSYGKSDDSSEHLDERYRDDLLSIGAIVSR
.  ..|. .|... .....|. . .... | ... .|..|.        |.| .. ..... | .  ..... . |...... . .|...  .|  .   
MNCCHMIHNLHHLHNNNHIHCDINPNNIWINQNNIHMCHNCGHNIPTIIIEHQHIKIMDFNNN-N-MMYFAPEF-SCRWCSPETFDYWPLGEKIDQYHFG

FLMNEEEMFKFSKSRNLKDIDWRVVLEGSSDSGLLDFNARSLLFQLLEGRQSARDLLR
..........  . ..   ..|. . . ... ..| .... ..... . ...  ....
CYHFHMNCQHWIFHYHDV-QHWPPHESPKDI-HILICQCECCHQCM-VNPYQNPNCFY
Kinase K11H12.9.AA CAMK 129-220 21 1.1e-11 33.23 In-house 57-205 (425) Show / Hide 
Range on Protein: 129-220
Range on HMM: 57-205/425
Sequence Identity: 21% (32 aa)

TIRKI---------SLQDPATARREYRNIILCRLLP----HPNILPISEAYE------------VDST--------LYTVS---EQMDGR------LSDI
.|.|.         . .| .  |||..   ... .     ||||. . |.||              |.        .| |    | ..|       .. |
KIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYI

VEE----------------RLTHFVVAKISHQILAAVAMMHQNGIAHGDL
||                 |.|   .... .||. ||. .|...|.| ||
VEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDL
Kinase K11H12.9.AA CMGC 130-220 15 5.6e-10 28.02 In-house 43-210 (513) Show / Hide 
Range on Protein: 130-220
Range on HMM: 43-210/513
Sequence Identity: 15% (27 aa)

IRKISLQ-DPATAR----------REYRNIILCRLLP-----------------HPNILPISEAYEVDS-----------------TLYTVSEQMDGRLS
| ||... .. .|.          | .| | . . |                  |.||. . . .  .                   || | | ||  | 
IKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLY

DIVEE-----------RLTHFV------------VAKIS------HQILAAVA--MMHQNG--IAHGDL
.. ..            |.. .            . ...      .||| ...   .|...  | | ||
QYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDL
Kinase K11H12.9.AA JNK 115-239 28 1.2e-09 32.14 In-house 14-151 (309) Show / Hide 
Range on Protein: 115-239
Range on HMM: 14-151/309
Sequence Identity: 28% (39 aa)

ISCSATDLLESDHVTIRKIS----LQDPATARREYRNIILCRLLPHPNILPISEAYEVDSTL------YTVSEQMDGRLSDIVE---ERLTHFVVAKISH
| |.| |..    | | |..    .|.   ..| ||  |.  .. |.||  .  ..  . ||      |.| | ||. | ...    ..| | ..  .  
IVCMAFDQVTNQRVAIKKMMRPDNFQNWMHWKRAYREFICMKCINHKNIIKMYNCFTPQETLEEFQDVYIVMEYMDWNLCQVIHSTFMELDHERMSYLFY

QILAAVAMMHQNGIAHGDLTLSTIYVNTDAELRLSSYG
|.. ..  .|  || | ||  | | ||.|. | ..  |
QMCCGIKHLHSMGIIHRDLKPSNIVVNQDCTLKICDFG
Kinase K11H12.9.AA S_TKc 102-327 17 2.2e-09 -39.31 SMART 1-231 (231) Show / Hide 
Range on Protein: 102-327
Range on HMM: 1-231/231
Sequence Identity: 17% (46 aa)

IELNAGTSTRSTSISCSATDLLESDHVTIRKISLQDPATARREYRNIILCRLLPHPNILPISEAYEVDSTLYTVSEQMDG---RLSDIVEER--------
 |.       . .  . ...     .| | .|.       .. .| | ...   ||||  . ....  . || | | .||    | |. ..|        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LTHFVVAKISHQILAAVAMMHQNGIAHGDLTLSTIYVNTDAELRLSSYGKSDDSSEHLDER---------------Y-RDDLLSIGAIVSRFLM------
..  ..... .||. |.. .|..|| | ||  . | ...  .. ..  | .       .                 . . |  |.| |.  .|       
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFP

NEEEMFKFSKSRNLKDIDWRVVLEGSSDSGLLDFNARSLLFQLLE----GRQSARDLLR-------HPYF
....|||  .                      .  |.... ..|.     | .| ..|.       ||.|
QMQMMFKKIG----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase K11H12.9.AA Ciliate-E2 147-223 19 5.2e-09 27.05 In-house 68-190 (365) Show / Hide 
Range on Protein: 147-223
Range on HMM: 68-190/365
Sequence Identity: 19% (24 aa)

NII--------------LCRLLPHPNILPISEAYE--VDSTLYTVSEQMDGR-LSDIVEER-------------LTHFVVAKISHQILA-----------
.|.              ....| ||||. . |...   |...| | |  .|  | |. ...             .|.. ...|. |||            
HIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIA

----AVAMMHQNG-IAHGDLTLS
    |.  .|... | | |. ..
CIILALEYLHSKNNIIHRDIKPE
Kinase K11H12.9.AA Pkinase 152-220 26 5.7e-09 32.81 Pfam 55-134 (293) Show / Hide 
Range on Protein: 152-220
Range on HMM: 55-134/293
Sequence Identity: 26% (21 aa)

RLLPHPNILPISEAYEVDSTLYTVSEQMDG-----RLSDIVE----ERL--THFVVAKISHQILAAVAMMHQNGIAHGDL
. | ||||. . ...| .. .| | | ..|      |.|...     ..  .  .. ..  ||| ... .|..|| | ||
KRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDL
Kinase K11H12.9.AA CAMK-Unique 150-220 20 1.1e-08 24.55 In-house 69-183 (363) Show / Hide 
Range on Protein: 150-220
Range on HMM: 69-183/363
Sequence Identity: 20% (23 aa)

LCRLLPHPNILPISEA----YEVDS---------------TLYTVSEQMDGR-LSDIVEER-------------------LTHFVV-----AKISHQILA
. ... ||||... .     .. .                 .|.| |  .|. |.|.. ..                    .||       . |. ..| 
IWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLS

AVAMMHQNGIAHGDL
||| ||...| |.||
AVAYMHSQDIVHRDL
Kinase K11H12.9.AA NuaK 129-222 29 2.8e-08 17.32 In-house 31-127 (252) Show / Hide 
Range on Protein: 129-222
Range on HMM: 31-127/252
Sequence Identity: 29% (29 aa)

TIRKISLQDPATARREYRNIILCRLLPHPNILPISEAYEVDSTLYTVSE-QMDGRLSDIVEE--RLTHFVVAKISHQILAAVAMMHQNGIAHGDLTL
.|.|   .|..  ..  | | .   | ||.|  | | .|  . .  | |    | | | ..|  .|.   . ..  ||  ||.  |...|.| || |
SIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPEREARHFFRQIVSAVHYCHKHRICHRDLKL
Kinase K11H12.9.AA MAPK 117-193 28 7.3e-08 23.04 In-house 16-114 (328) Show / Hide 
Range on Protein: 117-193
Range on HMM: 16-114/328
Sequence Identity: 28% (28 aa)

CSATDLL------ESDHVTIRKIS--LQDPATARREYRNIILCRLL-PHPNILPISEAYEV------DS-----TLYTVSEQMDGRLSDIVE-ER-LTH
|||.| .      . ..| | |||   |.|  ..| || |.| | .  |.||  . . .        .|     ..| |.| |.  |  | . .. |..
CSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMETDLHQIIKSQQPLSD
Kinase K11H12.9.AA STE 149-220 24 8.5e-08 23.75 In-house 81-178 (359) Show / Hide 
Range on Protein: 149-220
Range on HMM: 81-178/359
Sequence Identity: 24% (24 aa)

ILCRLLP-HPNILPISEAYEVD-------STLYTVSEQMD-GRLSDIVE----------------ERLTHFVVAKISHQILAA-VAMMHQNGIAHGDL
|. .. . ||||     .|...       ..|. . | || | |.||..                 |.   ..|.| .||| .  .  |...| | |.
IMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDI
Kinase K11H12.9.AA PAKB 156-239 34 3e-06 19.2 In-house 55-140 (252) Show / Hide 
Range on Protein: 156-239
Range on HMM: 55-140/252
Sequence Identity: 34% (30 aa)

HPNILPISEAYEVDSTLYTVSEQMD-GRLSDIV-EERLTHFVVAKISHQILAAVAMMHQNGIAHGDLTLSTIYVNTDAELRLSSYG
||||  . . | |.  |  | | |. | | ||| . |..   .| ...|.| | | .|  |. | |     |    |   .|| .|
HPNIVEMYSSYLVGDELWVVMEFMEGGALTDIVTHTRMNEEQIATVCRQVLQALAYLHAQGVIHRDIKSDSILLTHDGRVKLSDFG
Kinase K11H12.9.AA CMGC 317-327 54 0.001557 6.45 In-house 503-513 (513) Show / Hide 
Range on Protein: 317-327
Range on HMM: 503-513/513
Sequence Identity: 54% (6 aa)

SARDLLRHPYF
.| . |.||||
TAEQALQHPYF
Kinase K11H12.9.AA PAKB 315-327 53 0.001679 8.85 In-house 240-252 (252) Show / Hide 
Range on Protein: 315-327
Range on HMM: 240-252/252
Sequence Identity: 53% (7 aa)

RQSARDLLRHPYF
| .| .|||||..
RWTAQELLRHPFL
Kinase K11H12.9.AA MAPK 315-327 46 0.011792 4.74 In-house 316-328 (328) Show / Hide 
Range on Protein: 315-327
Range on HMM: 316-328/328
Sequence Identity: 46% (6 aa)

RQSARDLLRHPYF
| .. . |.||||
RITVEEALQHPYF
Kinase K11H12.9.AA STE 315-327 40 0.017085 4.77 In-house 345-359 (359) Show / Hide 
Range on Protein: 315-327
Range on HMM: 345-359/359
Sequence Identity: 40% (6 aa)

RQSARDLLR--HPYF
| .| .||.  || .
RPTASQLLKSEHPFI
Kinase K11H12.9.AA JNK 304-327 46 0.045206 3.65 In-house 282-309 (309) Show / Hide 
Range on Protein: 304-327
Range on HMM: 282-309/309
Sequence Identity: 46% (13 aa)

ARSLLFQLL----EGRQSARDLLRHPYF
|| |||  |    . | |  | |.||| 
ARDLLFRMLVINPDDRISVDDALQHPYI
Kinase K11H12.9.AA Ciliate-E2 317-327 36 0.165462 0.92 In-house 355-365 (365) Show / Hide 
Range on Protein: 317-327
Range on HMM: 355-365/365
Sequence Identity: 36% (4 aa)

SARDLLRHPYF
.. ..| ||.|
GWEQILNHPWF
Kinase K11H12.9.AA Pkinase 317-327 45 1.013255 3.63 Pfam 283-293 (293) Show / Hide 
Range on Protein: 317-327
Range on HMM: 283-293/293
Sequence Identity: 45% (5 aa)

SARDLLRHPYF
.|...| ||.|
TAEQILQHPWF