Gene kin-16 (Nematode worm)

kin-16

Species: Nematode worm
Alias: aSWK387, kin-16, M176.7, CE12472
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: II: 9436014-9433991, WormBase Genetic Map location: n/a,

Classification

Group: TK
Family: KIN16

Sequence

Name Sequence Type Origin Length Description Download
kin-16.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 315 Kinase domain by global Sugen HMM Fasta, JSON
kin-16.AA Protein Genbank 495 None Fasta, JSON

Protein domain

Protein domains of kin-16.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase kin-16.AA KIN16 140-454 57 3.7e-257 763.42 In-house 1-332 (332) Show / Hide 
Range on Protein: 140-454
Range on HMM: 1-332/332
Sequence Identity: 57% (191 aa)

LENKSILGSGNFGVVRKGILKMASPKNEEEKKMRLTVAVKSAANCYDISQTSMLAAELRLMCSIGRFPNVLALVGAVTSELRKGR---LLIVTEYIDCGD
||....||||.|||||||.|.|..||||.|.|.||.|||||.||..||.|..|.. ||..||.||..|||||||||||...|.|.   |.|||||..|||
LEFEEPLGSGHFGVVRKGLLHMKNPKNEKEHKNRLEVAVKSPANPHDICQQKMIYDELKVMCAIGKHPNVLALVGAVTKNMRQGGRHMLMIVTEYVECGD

IRKYLIDHRNVFQDHLIEDKTEPDSYLTPISAKRKNYVFKNTDENSDYVIKESLDSLTTSDLLSFGLQIANGMQYLASIPM-VHRDLALRNVLLKKNKTI
.||.|..|||.||.|......|..|........||.|||||..||...|||...|||.|||||||..||||||..||..|. ||||||.|||..|.||.|
LRKFLRQHRNNFQNHQVCWDNERQSGYNINNKERKHYVFKNFCENEQLVIKDIFDSLCTSDLLSFAYQIANGMEWLAHVPCCVHRDLACRNVFIKRNKII

RIADFGMARTHENKSYYIPQKTKDAPVPVRWMSPEAFDT-----MKFTEKSDVWSFGICLYEIFTLGQLPYPDVPSER--------IYEYMHSGRRCPQP
||||||.||.||||.||......|.|.|.|||.||.|..     |||||||||||.|.||||||.||..|||..|...        ..||...|.|.|||
RIADFGLARWHENKDYYRMKSSMDTPLPMRWMAPECFEEEQERKMKFTEKSDVWSYGVCLYEIFSLGETPYPNCPNNNCRDDYFQYVMEYLRKGNRLPQP

QHCHVELYDLMKLCWHEKPELRPNFSNCVEYF
.||| |.||.||.||. .|| ||.||.|||.|
EHCHPEIYDFMKMCWNFDPEKRPTFSECVEFF
Kinase kin-16.AA Pkinase_Tyr 140-454 35 1.7e-129 439.23 Pfam 1-270 (270) Show / Hide 
Range on Protein: 140-454
Range on HMM: 1-270/270
Sequence Identity: 35% (114 aa)

LENKSILGSGNFGVVRKGILKMASPKNEEEKKMRLTVAVKSAANCYDISQ--TSMLAAELRLMCSIGRFPNVLALVGAVT-SELRKGRLLIVTEYIDCGD
..    ||.|.||.|.||..|.      .... ...||||.  . .. .|    .. .|...|...|. ||.. |.|..|  .  . ...||.||  .||
ITFGKKLGEGAFGEVYKGTWKG------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGD

IRKYLIDHRNVFQDHLIEDKTEPDSYLTPISAKRKNYVFKNTDENSDYVIKESLDSLTTSDLLSFGLQIANGMQYLASIPMVHRDLALRNVLLKKNKTIR
 ..|| .||                                          |. ..||..|||.. .|||.||.||.|....||||| ||.|...|....
LLDYLRKHR------------------------------------------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVK

IADFGMARTHENKSYYIPQKTKDAPVPVRWMSPEAFDTMKFTEKSDVWSFGICLYEIFTLGQLP-YPDVPSERIYEYM-HSGRRCPQPQHCHVELYDLMK
|.|||.||...|..||  .|......|..||.||.. ..|||.||||||||....||||.|. | ||... |..|||   .|.| |.|..|. |.|||||
ICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMK

LCWHEKPELRPNFSNCVEYF
.|||..|| || || ..| .
QCWHYDPEDRPTFSEIHEQL
Kinase kin-16.AA TyrKc 140-454 34 2.3e-127 430.35 SMART 1-280 (280) Show / Hide 
Range on Protein: 140-454
Range on HMM: 1-280/280
Sequence Identity: 34% (118 aa)

LENKSILGSGNFGVVRKGILKMASPKNEEEKKMRLTVAVKSAANCYDISQTSMLAAELRLMCSIG-RFPNVLALVGAVTSELRK----GRLLIVTEYIDC
.. . .||.|.||.|.||..|             ..||||.  ..       ..  |.|.||..| . ||...|.|..|.. |.    . |.||.|| . 
ITLGKKLGEGAFGEVYKGTWK-------------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH

GDIRKYLIDHRNVFQDHLIEDKTEPDSYLTPISAKRKNYVFKNTDENSDYVIKESLDSLTTSDLLSFGLQIANGMQYLASIPMVHRDLALRNVLLKKNKT
|| ..|| .||.                                              |...||||| .|||.||.||.| . .||||| ||.|...|.|
GDLKDYLRKHRPK---------------------------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHT

IRIADFGMARTHENK-------SYYIPQKTKDAP--VPVRWMSPEAFDTMKFTEKSDVWSFGICLYEIFTLGQLPYPD-----VPSERIYEYMHSGRRCP
..|.|||..| ....       .|| ....|..   .|.|||.||.... |||.||||||||.|..||||.|| |||.     .. ....||  .|.| |
VKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMP

QPQH--------CHVELYDLMKLCWHEKPELRPNFSNCVEYF
||..        |. |.|..|| ||||.|| ||.||...|.|
QPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase kin-16.AA TK 140-454 25 2.9e-116 391.47 In-house 1-486 (486) Show / Hide 
Range on Protein: 140-454
Range on HMM: 1-486/486
Sequence Identity: 25% (123 aa)

LENKSILGSGNFG---VVRKGILKMASPKNEEE---------------KKMRLTVAVKSAANCYDISQTSMLA----------------AELRLMCS-IG
..    ||.|.||   .|.||.... .|.|...               .. . .||||      . ||. ...                .|. .||. .|
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RFPNVLALVGAVTSELRK---------GRLLIVTEYIDCGD----IRKYLIDHRNVFQDHLIEDKTEPDSYL------------TPISAKRKNYVFKNTD
. ||.. |.|..| .  |         . ..||.|| ..||     |.|| ..|. ||... .  .... |.            |. |.... .   . .
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITY-SHESNSPC-PEEQ

ENSDYVIKESLDSLTTSDLLS-------------------FGLQIANGMQYLASIP------MVHRDLALRNVLLKKNKT-----------IRIADFG--
.. |..||.....|||.|||.                   . .|||.||.||.| .      .|||||| ||.|. .|..           ..|||||  
DYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------MARTHENKSYYIPQKTK----------------------DAPVPVRWMSPEAFD---------TMKFTEKSDVWSFGICLYEIFTLG-QLPYPD
      .|| ......|  ....                      .. .|.|||.||...         . |||.||||||||....||||.| . .|..
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

VPS---------ERIYEYMHSG--------------RRCPQPQHCH--------------VELYDLMKLCWHEKPELRPNFSNCVEYF
...         . ..||  .|               |.|||.||.               |.||||. |||..|| ||.|| ..|..
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase kin-16.AA TK-Unique 140-454 31 2.1e-82 280.05 In-house 1-294 (294) Show / Hide 
Range on Protein: 140-454
Range on HMM: 1-294/294
Sequence Identity: 31% (104 aa)

LENKSILGSGNFGVVRKGILKMASPKNEEEKKMRLTVAVKSAANCYDISQTSMLAAELRLMCSIGRFPNVLALVGAVTSELRKGRLLIVTEYIDCGDIRK
||.....|.|.|| | .| ..  .    ..   .  ||||    . .  . ...  |...| ..|. ||.. ..|. |.    .. .|. ||. ||. ..
LEVGDVIGEGAFGQVWRGEVWGIW----KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD--EPWMIIMEYCPCGNLQH

YLIDHR----------NVFQDHLIEDKTEPDSYLTPISAKRKNYVFKNTDENSDYVIKESLDS-LTTSDLLSFGLQIANGMQYLASIPM--VHRDLALRN
||   |          |.                                .  ... .. ... ..  ||..|. |||.||.|||| ..  |||||. ||
YLRTCRPAMRQHQTYGNLK-------------------------------FDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARN

VLLKKNKTIRIADFGMARTHENKSYYIPQKTKDAPVPVRWMSPEAFD--TMKF-TEKSDVWSFGICLYEIFTLGQLPYPDVPSERIYEYMHSGRRCPQPQ
|||  .|.. |.||||||  ..    .  ...  ..|.|||.||..   .  . |.||||||||. ..||||||. |||..|...| | .  | |.|||.
VLLTEDKVCKICDFGMARDVYT-NGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPE

HC-HVELYDLMKLCWHEKPELRPNFSNCVEYF
||   |.| ||| ||...|| ||.|. ..  .
HCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase kin-16.AA UTK 140-454 29 4.5e-69 235.45 In-house 1-296 (296) Show / Hide 
Range on Protein: 140-454
Range on HMM: 1-296/296
Sequence Identity: 29% (101 aa)

LENKSILGSGNFGVVRKGILKMASPKNEEEKKMRLTVAVKSAANCYDISQTSML-AAELRLMC----SIGRFP---NVLALVGAVTSELRKGRLLIVTEY
..    ||.|.||.|.|. .. .|.  ..| .....|..       . .|...  ...... .      ..|    ||| ||| .|.|     ..|||||
VQLGRQLGQGAFGEVHKARFTQCSEH-MYEMDVAVKVCQ-----HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP---WMIVTEY

IDCGDIRKYLIDHRNVFQDHLIEDKTEPDSYLTPISAKRKNYVFKNTDENSDYVIKESLDSLTTSDLLSFGLQIANGMQYLASIPMVHRDLALRNVLLKK
   || |.|| .||  .                                       .  ..||  ..|.. ..||.|||||.|   |||||| ||.|. .
MENGDLRSYLRRHRPTPP--------------------------------------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHM

N-------KTIRIADFG---MARTHE-------NKSYYIPQKTKDAPVPVRWMSPEAFDTM-KFTEKSDVWSFGICLYEIFTLGQLPYPDVPSERIYEYM
.        ...|||||   |.|           ...|  ... . ..|.|||.|||.. . .||.||||||||. ..||.| |.||||.   ... .  
HRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQV

HSG--RRCPQPQHCHVELYDLMKLCWHEKPELRPNFSNCVEYF
. |  .| |.|..|  ..|.||. |||  |. ||.|   |. .
CNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase kin-16.AA FGFR 276-454 42 1.7e-66 225.65 In-house 108-293 (293) Show / Hide 
Range on Protein: 276-454
Range on HMM: 108-293/293
Sequence Identity: 42% (79 aa)

KNTDENSDYVIKESLDS--------LTTSDLLSFGLQIANGMQYLASIPMVHRDLALRNVLLKKNKTIRIADFGMARTHENKSYYIPQKTKDAPVPVRWM
|...|  ||  . . .         ||  || |.  |.| ||.||||   .||||| ||||   .  . |.||| ||   .  ||   || .   |. ||
KDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYY--RKTTNGRLPIKWM

SPEAFDTMKFTEKSDVWSFGICLYEIFTLGQLPYPDVP-SERIYEYMHSGRRCPQPQHCHVELYDLMKLCWHEKPELRPNFSNCVEYF
 ||| .  ..| .|||||.|. | ||.|.|. ||| .|  | .|.|  .|.|   |..|  |.| .|  |||.||. || |   |||.
APEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase kin-16.AA Met 293-448 43 4.1e-64 209.01 In-house 101-271 (271) Show / Hide 
Range on Protein: 293-448
Range on HMM: 101-271/271
Sequence Identity: 43% (75 aa)

LTTSDLLSFGLQIANGMQYLASIPMVHRDLALRNVLLKKNKTIRIADFGMARTH-ENKSYYIPQKTKD-APVPVRWMSPEAFD--------TMK-FTEKS
..  ||..|..|.| ||.|.||   |||||| || .| .  |. .|||| .|     |.||. .   . |  ||.|| ||           | . || ||
PCVRDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQMHHTHPARLPVKWMAPECLQQGVCLGCPTYRQFTTKS

DVWSFGICLYEIFTLGQLPYPDVPS-ERIYEYMHSG--RRCPQPQHCHVELY-DLMKLCWHEKPELRPNFS
||||||. . | .| |  |||.| .   |  . | |  || ||| .|   || |.|  ||| .|| || ||
DVWSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQPEYCPDHLYTDVMLCCWHANPEDRPQFS
Kinase kin-16.AA Src 226-454 32 1.6e-60 204.32 In-house 70-255 (255) Show / Hide 
Range on Protein: 226-454
Range on HMM: 70-255/255
Sequence Identity: 32% (76 aa)

LIVTEYIDCGDIRKYLIDHRNVFQDHLIEDKTEPDSYLTPISAKRKNYVFKNTDENSDYVIKESLDSLTTSDLLSFGLQIANGMQYLASIPMVHRDLALR
.|||||   |   .|| .                                           ..   .|   .|.... |.|.||.|| |  ..||||| |
YIVTEYMSHGSLLDYLKK-------------------------------------------DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAAR

NVLLKKNKTIRIADFGMARTHE-NKSYYIPQKTKDAPVPVRWMSPEAFDTMKFTEKSDVWSFGICLYEIFTLGQLPYPDVPSERIYEYMHSGRRCPQPQH
|||  .|    .|||| ||  . ..  | ...  .| .|..|. |||..  .|| ||||||||| |.||.| |. |||    .   .    | | |.|..
NVLVGENNVCKVADFGLARLIKEDDDEYCARH--GAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHN

CHVELYD-LMKLCWHEKPELRPNFSNCVEYF
|  |||. .|. |||..|| || |    ...
CPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase kin-16.AA KIN6 297-454 41 7.4e-59 193.06 In-house 145-305 (305) Show / Hide 
Range on Protein: 297-454
Range on HMM: 145-305/305
Sequence Identity: 41% (68 aa)

DLLSFGLQIANGMQYLASIPMVHRDLALRNVLLKKNK---TIRIADFGMAR-THENKSYYIPQKTKDAP-VPVRWMSPEAFDTMKFTEKSDVWSFGICLY
||..|  ||..|| ||.|. ..||||| ||||. .     |  | |||..|     .. |   ..|     |..||.||.. . .|  ||||||||. ..
DLYMFAWQICDGMEYLHSKNCIHRDLAARNVLVTEGCRMKTCKISDFGLCRYPYMDQFQY---TSKGGRYLPIKWMAPECLKHYEFSYKSDVWSFGVLMF

EIFTLGQLPYPDVP-SERIYEYMHSGRRCPQPQHCHVELYDLMKLCWHEKPELRPNFSNCVEYF
|.|.||  |||...  . . | . ||||  .|  |  | || |..|| |||. ||.|.     |
EMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKWCPEEIYDIMQSCWQEKPDDRPEFNEMRMQF
Kinase kin-16.AA Fer 286-455 32 1.3e-56 191.32 In-house 100-283 (283) Show / Hide 
Range on Protein: 286-455
Range on HMM: 100-283/283
Sequence Identity: 32% (60 aa)

IKESLD-SLTTSDLLSFGLQIANGMQYLASIPMVHRDLALRNVLLKKNKTIR---IADFGMART--HENKSYYIP-QKTKDAPVPVRWMSPEAFDTMKFT
.|.. . .... ... . .|.|.||.|| |  ..|||.| ||.|. |.|.     |.||||.|.   . ..|. .   .|   ||.||..||...|. ..
LKKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACK---VPIRWLAPETWQTGIYS

EKSDVWSFGICLYEIFTLGQLPYPD---------VPSERIYEYMHSGRRCPQPQHCHVELYDLMK-LCWHEKPELRPNFSNCVEYFI
.|.||||||. ..|||| |. |||.         |. ...  . ..|.. | |.|...|.. .|.  ||...|| ||...  .. . 
PKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase kin-16.AA TKL 146-454 21 7.9e-56 191.8 In-house 1-364 (364) Show / Hide 
Range on Protein: 146-454
Range on HMM: 1-364/364
Sequence Identity: 21% (89 aa)

LGSGNFGVVRKGILKMAS---PKNEEEKKMRLTVAVKSAANCY-------------------------DISQTSMLAAELRLMCSIGRFPNVLALVGAVT
.||| ||.| ||...  .   |       .  .||||     .                         ..|.      |  .|.|  | ||.. ..|...
IGSGGFGEVYKGKWRGWGGKCP----S-DTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCC

SE----------LRKGRLLIVTEYIDCGDIRKYLIDHRNVFQDHLIEDKTEPDSYLTPISAKRKNYVFKNTDENSDYVIKESLDSLTTSDLLSFGLQIAN
..            .| | ||.||...|. . ||.                                                     . .... |.|| 
CPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------------------------------------------------WHQRCRWALDIAR

GMQYLAS--------IPMVHRDLALRNVLLKKNKT--------------IRIADFGMARTHENKSYYIPQK--------------TKDAPV-PVRWMSPE
||.|| |         |..||||  .|.|...| |              . |.||| .|......    ..              |.  ..   |||.||
GMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPE

AFDTM----------------KFTEKSDVWSFGICLYEIFTLGQLPYPDVPSERIY------EYMHS----GRRCPQP------------QHCHVELYDL
... .                ...||.||.||||.|.||.|  . || | |.. ..      |..      |.| | |             .|  .. .|
VLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKL

MKLCWHEKPELRPNFSNCVEYF
|. ||...|| ||.|. .....
MQDCWDHDPEKRPSFQEILKRL
Kinase kin-16.AA Pkinase 140-454 18 3.5e-31 111.32 Pfam 1-293 (293) Show / Hide 
Range on Protein: 140-454
Range on HMM: 1-293/293
Sequence Identity: 18% (67 aa)

LENKSILGSGNFGVVRKGILKMASPKNEEEKKMRLTVAVKSAANCYDISQTSMLAA---ELRLMCSIGRFPNVLALVGAVTSELRKGRLLIVTEYIDCG-
.. ....|||.||.|.|.. |  .           .||||    . . |.  . ..   |...| .. . ||.. | .....   |... .|.|| ..| 
YHIGRKIGSGSFGCVYKCHHKGTGK----------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED---KDHIYMVMEYCEGGL

---DIRKYLIDHRNVFQDHLIEDKTEPDSYLTPISAKRKNYVFKNTDENSDYVIKESLDSL--TTSDLLSFGLQIANGMQYLASIPMVHRDLALRNVLLK
   |   |.                                              ..  ..  .  .. .. .||. |..|. |   .|||| . |.|..
YVMDLFDYIST--------------------------------------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID

KNKTI----RIADFGMARTHENKSYYIPQKTKDAPVPVRWMSPEAFD-TMKFTEKSDVWSFGICLYEIFTLGQLPYPDV----PSERIYEYMHSGRRCPQ
.| .|    .|.||| |. ..   |   . ...  .  ..|.||      . . |.|.||.|. ||| .. |..|.|.     .  . .. .   ...| 
NNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPL

PQHCH-----------------------VELYDLMKLCWHEKPELRPNFSNCVEY--F
. ..                         |. |..| |.. .|. ||..  ...   |
HFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase kin-16.AA S_TKc 140-454 19 1.4e-25 92.24 SMART 1-231 (231) Show / Hide 
Range on Protein: 140-454
Range on HMM: 1-231/231
Sequence Identity: 19% (63 aa)

LENKSILGSGNFGVVRKGILKMASPKNEEEKKMRLTVAVKSAANCYDISQTSMLAAELRLMCSIGRFPNVLALVGAVTSELRKGRLLIVTEYIDC--GDI
 |   ..|.| ||.|.|.. |               ||.|            ..  |.... .  . ||.  | ..  .    ..| .|.||.|   || 
YEILRKIGKGAFGKVYKCRHKK----------TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDL

RKYLIDHRNVFQDHLIEDKTEPDSYLTPISAKRKNYVFKNTDENSDYVIKESLDSLTTSDLLSFGLQIANGMQYLASIPMVHRDLALRNVLLKKNKTIRI
..|. ...    ..                                         ..  .  ..  ||.....|. |   .||||   |.|| .  .| |
FDYIKKRGRHGLRFP----------------------------------------FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKI

ADFGMARTHENKSYYIPQKTKDAPVPVRWMSPEAFDTMKFTE-KSDVWSFGICLYEIFTLGQLPYPDVPSERIYEYMHSGRRCPQPQHCHVELYDLMKLC
.|||.||             .   .   .|.|| .   ...  |.|.||.|..||| .. |. |.|    ..... .              |. |... |
CDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKC

WHEKPELRPNFSNCVE---------YF
..  || ||    . .         .|
LQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase kin-16.AA Fer 140-168 35 0.004151 6.56 In-house 1-31 (283) Show / Hide 
Range on Protein: 140-168
Range on HMM: 1-31/283
Sequence Identity: 35% (11 aa)

LENKSILGSGNFGVVRKG--ILKMASPKNEE
 . . .||.|.|| |.||   ||.  .|. .
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHV
Kinase kin-16.AA FGFR 140-245 31 0.010253 5.02 In-house 1-100 (293) Show / Hide 
Range on Protein: 140-245
Range on HMM: 1-100/293
Sequence Identity: 31% (34 aa)

LENKSILGSGNFGVVRKGILK-MASPKNEEEKKMRLTVAVKSAANCYDISQTSMLAAELRLMCSIGRFPNVLALVGAVTSELRKGRLLIVTEYIDCGDIR
|   ..|| | || | ..  | .   . |.|     |||||           | |  |.  |  ||. .|.. | |. | |   | | .. ||   |  |
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKE----ITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQE---GPLYVIVEYCHHGNLR

KYLIDHR
 .|  .|
DFLRARR
Kinase kin-16.AA Met 141-246 24 0.021159 3.35 In-house 1-99 (271) Show / Hide 
Range on Protein: 141-246
Range on HMM: 1-99/271
Sequence Identity: 24% (27 aa)

ENKSILGSGNFGVVRKGILKMASPKNEEEKKMRLTVAVKSAA--NCYDISQTSMLAAELRLMCSIGRFPNVLALVGAVTSELRKG-RLLIVTEYIDCGDI
    ..| | ||.| .|  ..  .. .|..     .|.||       || . |    | ..|      ||||.|.|   .    |   ..|..|   ||.
HFDDVIGQGHFGCVYHG--MYHDNDGNEHH-----CACKSLHGERITDIQHISQFLREGIMMKHF-DHPNVLSLIGICLDP--EGHMPWVVLPYMKHGDL

RKYLIDHRN
...  .  |
KTFIRNPQN
Kinase kin-16.AA KIN6 140-184 24 0.069985 1.77 In-house 1-45 (305) Show / Hide 
Range on Protein: 140-184
Range on HMM: 1-45/305
Sequence Identity: 24% (11 aa)

LENKSILGSGNFGVVRKGILKMASPKNEEEKKMRLTVAVKSAANC
  .   ||.| |. | ||..|  ||  .      ...  . . .|
IHKDHKLGHGAFCNVYKGKIKGKSPIMQWINRVNMRIEMMRYQDC