Gene kin-18 (Nematode worm)

kin-18

Species: Nematode worm
Alias: T17E9.1, T17E9.1a, CE01405, kin-18, Sulu, aSWK313
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: III: 6114373-6119004, WormBase Genetic Map location: n/a,

Classification

Group: STE
Family: STE20
Subfamily: TAO

Sequence

Name Sequence Type Origin Length Description Download
kin-18.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 260 Kinase domain by global Sugen HMM Fasta, JSON
kin-18.AA Protein Genbank 982 None Fasta, JSON

Protein domain

Protein domains of kin-18.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase kin-18.AA TAO 30-289 69 1.5e-189 624.7 In-house 1-254 (254) Show / Hide 
Range on Protein: 30-289
Range on HMM: 1-254/254
Sequence Identity: 69% (181 aa)

YQDLREIGHGSFGAVYFAYDKKNEQTVAIKKMNFSGKQAVEKWNDILKEVSFLNTVVHPHIVDYKACFLKDTTCWLVMEYCIGSAADIVDVLRKGMREVE
.|||||||||||||||||.||..|..||||||..||||..|||.||.|||.||..|.||....||.|.|...|||||||||.|||.||.||..|.|.|||
FQDLREIGHGSFGAVYFARDKHTEEVVAIKKMSYSGKQSHEKWQDIIKEVRFLQQVKHPNCIEYKGCYLREHTCWLVMEYCLGSASDILDVHKKPMQEVE

IAAICSQTLDALRYLHSLKRIHRDIKAGNILLSDHAIVKLADFGSASLVDPAQTFIGTPFFMAPEVILAMDEGHYTDRADIWSLGITCIELAERRPPLFS
|||||...|..||||||.|.||||||||||||..|..||||||||||.|.||..|.|||..||||||||||||.|....|.|||||||||||||.||||.
IAAICHGALQGLRYLHSHKMIHRDIKAGNILLTEHGQVKLADFGSASMVCPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFN

MNAMSALYHIAQNDPPTLSPIDTSEQPEWSLEFVQFIDKCLRKPAEERMSAEECFRHPFI
||||||||||||||.|||.      |.||| .|.||.||||.|...||.|||||.||.|.
MNAMSALYHIAQNDSPTLQ------QNEWSDCFHQFVDKCLQKMPQERPSAEECLRHEFV
Kinase kin-18.AA STE20 30-289 45 2.4e-135 455.93 In-house 1-288 (288) Show / Hide 
Range on Protein: 30-289
Range on HMM: 1-288/288
Sequence Identity: 45% (132 aa)

YQDLREIGHGSFGAVYFAYDKKNEQT----VAIKKMNFSGK---QAVEKWNDILKEVSFLNTVVHPHIVDYKACFLKD----TTCWLVMEYCIG-SAADI
|..|..||.||.|.||.||.|.. .     ||||||| . .   |  ..|.||.||.|...   ||.|| |  ..|||    .  |.||||| | |. ||
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQ--DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDI

VD---VLRK-----GMREVEIAAICSQTLDALRYLHSLKRIHRDIKAGNILLSDHAIVKLADFG-SASLVD--------PAQTFIGTPFFMAPEVILAMD
..   .. |      | |..||.|| ..| .| |||| ..|||||||.||||.... ||||||| .|.| .        . .||.|||..||||||. |.
MKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCME

--EGHYTDRADIWSLGITCIELAERRPPLFSMNAMSALYHIA--QNDPPTLSPIDTSEQPEWSLEFVQFIDKCLRKPAEERMSAEECFRHPFI
  .. |. ..||||||||.||.||..||.| |..|.|...|.  ||.||||. . .  .  || || .|.|||| |  |.| .|..  .||||
GPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDD-K--PHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase kin-18.AA STE 30-289 30 6.2e-113 381.5 In-house 1-359 (359) Show / Hide 
Range on Protein: 30-289
Range on HMM: 1-359/359
Sequence Identity: 30% (112 aa)

YQDLREIGHGSFGAVYFAYDK------KNEQT---------VAIKKMNFSGKQA--------------VEKWNDILKEVSFLNTVV--HPHIVDYKACFL
......||.|.|| || |...      |. ..         .|||.||.. ...               |....||||.....     ||.|| |  |..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KD-------TTCWLVMEYCI-GSAADIVD-VLRKGMR------------EVEIAAICSQTLDA-LRYLHSLKRIHRDIKAGNILLSDHAIVKLADFGSAS
|.       ...|..|||.  ||. ||.. .  .|..            | .||.|| |.| . | ||||...||||||..||||     |||.||| ..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

LVDP--------------------AQTFIGTPFFMAPEVILAMDEG---HYTDRADIWSLGITCIELAERRPPLFSMNAMSALYHIAQN-----------
 ...                     .||.||| .||||||. ...|   .|. ..||||||.|.||.|. .||.. |. |.|...|..|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----DPPTLSPIDTSE------------QPEWSLEFVQFIDKCLRKPAEERMSAEECFR--HPFI
    .||.| .   ..            . .|| || .||.|||.|  ..| .|..  .  ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase kin-18.AA MST 30-289 43 3.4e-100 319.17 In-house 1-254 (254) Show / Hide 
Range on Protein: 30-289
Range on HMM: 1-254/254
Sequence Identity: 43% (116 aa)

YQDLREIGHGSFGAVYFAYDKKNEQTVAIKKMNFSGKQAVEKW-NDILKEVSFLNTVVHPHIVDYKACFL--KDTTCWLVMEYC-IGSAADIVDVLRKGM
.  .  .| ||.| || | .|.. . ||||...      |.   ..|.|| |..     ..|| | . ..  |...||.||||| .||..||.   ..  
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVP------VNEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTL

REVEIAAICSQTLDALRYLHSLKRIHRDIKAGNILLSDHAIVKLADFG-SASLVD---PAQTFIGTPFFMAPEVILAMDEGHYTDRADIWSLGITCIELA
 |..||.|...||  | |||. |.||||||||||||.     |||||| |. | |    ..|.||||..||||||    |  |.  |||||||||.||.|
NEQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVI---QEIKYDCKADIWSLGITAIEMA

ERRPPLFSMNAMSALYHIAQNDPPTLSPIDTSEQPEWSLEFVQFIDKCLRKPAEERMSAEECFRHPFI
| .||..   .|.|.  | |. |||.     ..  .|| ||  |. ||| |  |.| .||.   ||||
EGMPPYSDIHPMRAMFMIPQKPPPTF-----KDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase kin-18.AA S_TKc 30-289 31 4.1e-91 309.93 SMART 1-231 (231) Show / Hide 
Range on Protein: 30-289
Range on HMM: 1-231/231
Sequence Identity: 31% (87 aa)

YQDLREIGHGSFGAVYFAYDKKNEQTVAIKKMNFSGKQAVEKWNDILKEVSFLNTVVHPHIVDYKACFLKDTTCWLVMEYCIGSAADIVDVLRKG-----
|. ||.||.|.|| || ...||  . ||||...          ..|..|.. |    ||.|| .. .|   .  ..||||| |.. |  |...|      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---MREVEIAAICSQTLDALRYLHSLKRIHRDIKAGNILLSDHAIVKLADFGSASLVDPAQTFIGTPFFMAPEVILAMDEGHYTD-RADIWSLGITCIEL
   . | ... .. |...|| |.||.. ||||.|  ||||..   .|..|||.| ..    ||.|||..|||||.      .|.  ..|.||.|.. .|.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCILYEM

AERRPPLFSMNAMSALYHIAQNDPPTLSPIDTSEQPEWSLEFVQFIDKCLRKPAEERMSAEECFR-------HPFI
. ..||      | .....                   | |. .||.|||.|  |.|..| |...       ||..
LCGYPPFP---QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase kin-18.AA YSK 30-289 40 2e-83 251.0 In-house 1-257 (257) Show / Hide 
Range on Protein: 30-289
Range on HMM: 1-257/257
Sequence Identity: 40% (110 aa)

YQDLREIGHGSFGAVYFAYDKKNEQTVAIKKMNFSGKQAVEKWNDILKEVSFLNTVVHPHIVDYKACFLKDTTCWLVMEYCI-GSAADIVDVLRK----G
.  .  || |||| || ..|.. ...||||  .    .| .   || .|. ||     | |  | . .||||  | .||||  ||..|    ...    .
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDL--EHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDL---MKPKYVGQ

MREVEIAAICSQTLDALRYLHSLKRIHRDIKAGNILLSDHAIVKLADFGSASLVD----PAQTFIGTPFFMAPEVILAMDE-GHYTDRADIWSLGITCIE
. |  || |    | .| |||| . ||||||| |.||| |  |||.||| |. .       .||.|||..||||||  . |   |   ||||||||| .|
FDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVI--CQEVSYYDFKADIWSLGITAYE

LAERRPPLFSMNAMSALYHIAQNDPPTLSPIDTSEQPEWSLEFVQFIDKCLRKPAEERMSAEECFRHPFI
.|   ||.  . .| ..  |  | ||.|      |  ..|  |  |.. || |  |.| ||.|   | ||
MAKGEPPYCDYHPMRVMFLIPKNNPPKL------EGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase kin-18.AA PAKA 30-289 37 1.4e-71 244.16 In-house 1-260 (260) Show / Hide 
Range on Protein: 30-289
Range on HMM: 1-260/260
Sequence Identity: 37% (102 aa)

YQDLREIGHGSFGAVYFAYDKKNEQT--VAIKKMNFSGKQAVEKWNDILKEVSFLNTVVHPHIVDYKACFLKDTTCWLVMEY-CIGSAADIVDVLRK---
|. . .|| |. |.|| |...|..|.  ||||.||..     |.   |. | . ...  |. ||.|   .| |   |.||||   |.  |...  ..   
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKEL---IINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQC

-GMREVEIAAICSQTLDALRYLHSLKRIHRDIKAGNILLSDHAIVKLADFGSASLVDP----AQTFIGTPFFMAPEVILAMDEGHYTDRADIWSLGITCI
  | |  ||..| ..| .| ..|| .|||||||  ||||   . ||..||| .    .     .|  ||| .||||||.  .   |    ||||||| .|
NYMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQ---YDEKVDIWSLGIMAI

ELAERRPPLFSMNAMSALYHIAQN-DPPTLSPIDTSEQPEWSLEFVQFIDKCLRKPAEERMSAEECFRHPFI
|..|  ||  ...   |.| ||.|  |. .      ..  || || .| |||| .  ..| ||.|  .|||.
EMIEGEPPYLNEPPLRAMYLIATNGKPDIK------DPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase kin-18.AA SLK 30-289 39 8.9e-70 234.55 In-house 1-259 (259) Show / Hide 
Range on Protein: 30-289
Range on HMM: 1-259/259
Sequence Identity: 39% (105 aa)

YQDLREIGHGSFGAVYFAYDKKNEQTVAIKKMNFSGKQAVEKWNDILKEVSFLNTVVHPHIVDYKACFLKDTTCWLVMEYCIGSAADIVDV-LRKGMREV
.. . |.| | || || | .| ...  | | ..    .  |. .| . |.  | .. ||.||.    .  |   |...|.| | | | . | | ....| 
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEI---KDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTED

EIAAICSQTLDALRYLHSLKRIHRDIKAGNILLSDHAIVKLADFG-SASLVDPAQ---TFIGTPFFMAPEVIL--AMDEGHYTDRADIWSLGITCIELAE
 |. .| ....||..||| | ||||.||||||.     |.||||| || .  . |   ||||||..|||||..   . .  |  .||||||||| ||.|.
QIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQ

RRPPLFSMNAMSALYHIAQNDPPTLSPIDTSEQP-EWSLEFVQFIDKCLRKPAEERMSAEECFRHPFI
  ||   || |  |  |.. .||||      ||| .|| ||  |. ||| | .. | .... ..|...
MEPPHHEMNPMRVLLKIQKSEPPTL------EQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase kin-18.AA Pkinase 30-289 28 3.3e-68 237.71 Pfam 1-293 (293) Show / Hide 
Range on Protein: 30-289
Range on HMM: 1-293/293
Sequence Identity: 28% (85 aa)

YQDLREIGHGSFGAVYFAYDKKNEQTVAIKKMNFSGKQAVEKWNDIL-KEVSFLNTVVHPHIVDYKACFLKDTTCWLVMEYCIG-----SAADIVD-VLR
|. .| || |||| || ...|.....||.|... ...   .. ....  |.. .. . ||.|| .. .|  .. ...||||| |     . .|..    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KGM--REVEIAAICSQTLDALRYLHSLKRIHRDIKAGNILLSDHAIV----KLADFGSA----SLVDPAQTFIGTPFFMAPEVILAMDEGHYTDRADIWS
...   | |.  .. |.| .| |.|| . ||||.|  |||....  .    |..|||.|       ....|| |||..||||||.  .  .|. ..|.||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIR--GGQYYGPKVDMWS

LGITCIELAERRPPLFSM------NAMSALYHIAQNDPPTLSPIDTSEQ-------------PEWSLEFVQFIDKCLRKPAEERMSAEECFRHPFI
.|....|.. .|||  .       . |  .. | . ...  .| . |.              ..|| |. .||..||.|  ..| .||... ||..
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase kin-18.AA Ste20-DD1 30-289 40 6.3e-66 224.93 In-house 1-268 (268) Show / Hide 
Range on Protein: 30-289
Range on HMM: 1-268/268
Sequence Identity: 40% (111 aa)

YQDLREIGHGSFGAVYFA-------YDKKNEQTVAIKKMNFSGKQAVEKWNDILKEVSFL-NTVVHPHIVDYKACFLKDTTCWLVMEYCI-GSAADIVDV
.| .  || |||| |           .  | . .|.| .   .   ||      ||.  | ||.  | || |. |..|.     |||||  ||  ||.. 
FQIVEVIGQGSFGVVCTCRWMKKKDRNTNNNRVIACKFVEMNA-DDVEENSNLKKEIDILKNTMDCPYIVKYHGCYIKENMLMIVMEYCDGGSILDIMQM

LRKGMREVEIAAICSQTLDALRYLHSLKRIHRDIKAGNILLSDHAIVKLADFG-SASLV---DPAQTFIGTPFFMAPEVILA--MDEGHYTDRADIWSLG
  | . | .||||| |    | |||| . .||||||||.|.      |||||| |. .|      .| || |. |.||.|      .| |  .|||||||
CSKRLIEEQIAAICYQIVKGLVYLHSNRITHRDIKAGNVLVNKEGQPKLADFGVSTIAVNQGFKMNTVIGSPYWMSPEIIMPPKGSQG-YDQKADIWSLG

ITCIELAERRPPLFSMNAMSALYHIAQNDPPTLS-PIDTSEQPEWSLEFVQFIDKCLRKPAEERMSAEECFRHPFI
|| ||.||  ||.| .|     . |    ||||  | .      || ||  ||  || . .. | || .   ||||
ITAIEMAESKPPRFNVNPVRVIFVIPHQQPPTLKIPSN------WSPEFNDFIKQCLNMNPDKRPSAQQLLNHPFI
Kinase kin-18.AA KHS 30-289 38 1.9e-65 219.08 In-house 1-258 (258) Show / Hide 
Range on Protein: 30-289
Range on HMM: 1-258/258
Sequence Identity: 38% (101 aa)

YQDLREIGHGSFGAVYFAYDKKNEQTVAIKKMNFSGKQAVEKWNDILKEVSFLNTVVHPHIVDYKACFLKDTTCWLVMEYC-IGSAADIVDVLRKGMREV
|. |  .| | .| || | |.. .. .|.| . .   .. .    | .|.  . .  || || |   .|.    |..||||  ||  ||  |  . . |.
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKM---EPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGP-LSEL

EIAAICSQTLDALRYLHSLKRIHRDIKAGNILLSDHAIVKLADFG-SASL---VDPAQTFIGTPFFMAPEVILAMDEGHYTDRADIWSLGITCIELAERR
 || .| .|| .|.|||| ...|||||  ||||.|.  ||||||| || .   .   . |||||..|||||     .| |    |||..||| |||||  
QIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQ

PPLFSMNAMSALYHIAQNDPPTLSPIDTSEQPEWSLEFVQFIDKCLRKPAEERMSAEECFRHPFI
||.| .  | ||. ... .     |    ..  ||  | .|.  .| | .  | .||   .|||.
PPMFDLHPMRALFLMTKSN---FQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase kin-18.AA PAKL 32-289 39 8.5e-61 208.3 In-house 2-256 (256) Show / Hide 
Range on Protein: 32-289
Range on HMM: 2-256/256
Sequence Identity: 39% (105 aa)

DLRE-IGHGSFGAVYFAYDKKNEQTVAIKKMNFSGKQAVEKWNDILKEVSFLNTVVHPHIVDYKACFLKD-TTCWLVMEYC-IGSAADIVDVLRKGMREV
 . |  | ||.|.|| |  |    . ||| .       ..   || ||.. |     | || |        .  |  |.|| .||  |.  .  | . | 
EFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIK---DIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEK

EIAAICSQTLDALRYLHSLKRIHRDIKAGNILLSDHAIVKLADFG-SASLVDPAQ----TFIGTPFFMAPEVILAMDEGHYTDRADIWSLGITCIELAER
.|. |  |||  | ||||   ||||||| ||||.  ..||.|||| |  | |         ||||..||||.|.  .   |   .|||||||| ||.|. 
QISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQN---YNNKCDIWSLGITAIEMADG

RPPLFSMNAMSALYHIAQNDPPTLSPIDTSEQPEWSLEFVQFIDKCLRKPAEERMSAEECFRHPFI
.||.  |. | |.| |    |||.     |.   || .|. |...|. |  |.| |. .   ||||
FPPHYDMPPMRAMYMIPNWPPPTF-----SNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase kin-18.AA Pkinase_Tyr 30-173 26 3.7e-16 55.33 Pfam 1-156 (270) Show / Hide 
Range on Protein: 30-173
Range on HMM: 1-156/270
Sequence Identity: 26% (43 aa)

YQDLREIGHGSFGAVYFAYDK----KNEQTVAIKKMNFSGKQAVEK---WNDILKEVSFLNTV-VHPHIVDYKACFL-KDTT--CWLVMEYCIGSAADIV
 . ....|.|.|| || .. |    .....||.|...    .| ..   . | ..|.. . .   ||.|| . .. . ..     ..||||. .   |  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK---EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHG--DLL

DVLRKG------MREVEIAAICSQTLDALRYLHSLKRIHRDIKAGNILLSDHAIVKLADFG
| |||           ..  .| |  ... ||.| . ||||. | |.|...  .|| .|||
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase kin-18.AA TyrKc 30-289 22 8.7e-16 32.53 SMART 1-280 (280) Show / Hide 
Range on Protein: 30-289
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

YQDLREIGHGSFGAVYFAYDKKNEQTVAIKKMNFSGKQAVEKWNDILKEVSFLNTV--VHPHIVDYKACFLKD-------TTCWLVMEYCIGSAADIVDV
 . ....|.| || || .  |   ..||.|... .         |...| . .  .   ||.||   .. ...          ..||||. .   |  | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH--GDLKDY

LRKGMR---EVEIAAICSQTLDALRYLHSLKRIHRDIKAGNILLSDHAIVKLADFGSASLVDPA-------QTFI-----GTP-----FFMAPEVILAMD
|||  .     .   .| |  .  .|||| . ||||. | |.|...  .|| .||| .  ..         ..       |.        ||||.|   .
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---N

EGHYTDRADIWSLGITCIELAER-RPPLFS-----MNAMSALYHIAQN---DPPTL----SPIDTSEQPEWSLEFVQFIDKCLRKPAEERMSAEECFRHP
.| .|   |.|| |... |.  .  .|        |..  .. .. |    ..|      |    .  .. . |  | . .| .  .|.| . .|.  | 
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----F--VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HE

FI
..
CF
Kinase kin-18.AA Pkinase_Tyr 191-220 36 0.037839 7.9 Pfam 181-207 (270) Show / Hide 
Range on Protein: 191-220
Range on HMM: 181-207/270
Sequence Identity: 36% (11 aa)

MAPEVILAMDEGHYTDRADIWSLGITCIEL
||||.|  .    .|   |.|| |... |.
MAPECINYGK---FTTKSDVWSFGVLMWEI