Gene kin-30 (Nematode worm)

kin-30

Species: Nematode worm
Alias: M01B2.1, Cehd-5, CE16263, kin-30, aSWK390
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: V: 15247348-15250081, WormBase Genetic Map location: n/a,

Classification

Group: TK
Family: KIN16

Sequence

Name Sequence Type Origin Length Description Download
kin-30.AA Protein Genbank 483 None Fasta, JSON
kin-30.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 318 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of kin-30.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase kin-30.AA KIN16 133-451 48 4.4e-233 691.45 In-house 1-332 (332) Show / Hide 
Range on Protein: 133-451
Range on HMM: 1-332/332
Sequence Identity: 48% (170 aa)

DVFEKQFGQGNFGKVNKALLKLINQKT--GEVVRMDVAVKKPADSTDKSQDKLILDEIKLMCAIGKHPNVLAIVGAITKQEKVIGREHNLVVTEFVEGGD
. ||...|.|.||.|.|.||.. |.|.  ....|..||||.||...|..|.|.| ||.|.||||||||||||.|||.||.....||.....|||.||.||
LEFEEPLGSGHFGVVRKGLLHMKNPKNEKEHKNRLEVAVKSPANPHDICQQKMIYDELKVMCAIGKHPNVLALVGAVTKNMRQGGRHMLMIVTEYVECGD

LRSVLKYTP--YTFHDELTSTDRTGGQMVN--------------------SDIFDELSTSDLYSFAYQIANGMEYLAAKPVRFFWGKSGANFQFLKKSEF
||..|....  ...|.. ....|..|...|                    .||||.|.||||.|||||||||||.||  |.                   
LRKFLRQHRNNFQNHQVCWDNERQSGYNINNKERKHYVFKNFCENEQLVIKDIFDSLCTSDLLSFAYQIANGMEWLAHVPC-------------------

PKCVHRDLALRNVFVKRNKMIRIGDFGLARHHSKKSYYRMQCNPDTPLPIFWLAPECFNE-----SKFTEMTDVWSYGVCLFELFSLGESPYKKLHN---
  |||||||.||||.||||.|||.||||||.|..|.||||....|||||..|.|||||.|      ||||..|||||||||.|.|||||.||....|   
--CVHRDLACRNVFIKRNKIIRIADFGLARWHENKDYYRMKSSMDTPLPMRWMAPECFEEEQERKMKFTEKSDVWSYGVCLYEIFSLGETPYPNCPNNNC

--SPSYDVVHYLKKGYRLSAPRYCNAEIYEFMLYCWNIDATLRPKFTECKDFC
  .....|..||.||.||. |..|..|||.||..|||.|.. ||.|.||..| 
RDDYFQYVMEYLRKGNRLPQPEHCHPEIYDFMKMCWNFDPEKRPTFSECVEFF
Kinase kin-30.AA TyrKc 133-454 30 5.70000000001e-109 369.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 133-454
Range on HMM: 1-280/280
Sequence Identity: 30% (105 aa)

DVFEKQFGQGNFGKVNKALLKLINQKTGEVVRMDVAVKKPADSTDKSQDKLILDEIKLMCAIG-KHPNVLAIVGAITKQ-EKVIGREHNLVVTEFVEGGD
 ...|. | |.||.| |. .|           ..||||.  ...     . ...|...|| .| .|||.....|..|.| .. .  |  ..|.|....||
ITLGKKLGEGAFGEVYKGTWK-----------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD

LRSVLKYTPYTFHDELTSTDRTGGQMVNSDIFDELSTSDLYSFAYQIANGMEYLAAKPVRFFWGKSGANFQFLKKSEFPKCVHRDLALRNVFVKRNKMIR
|.. |...  .                       |...|| ||..|||.|||||. |                      .|.||||| ||. |..|. ..
LKDYLRKHRPK-----------------------LCMKDLLSFCWQIACGMEYLHSK----------------------NCIHRDLAARNCLVGENHTVK

IGDFGLARHHSKK-------SYYRMQC--NPDTPLPIFWLAPECFNESKFTEMTDVWSYGVCLFELFSLGESPYKKLHN--SPSYDVVHYLKKGYRLSAP
|.||||.| .  .       .|||..   . .|.||| |.||||.|..|||. .||||.|||..|.|..|..||        . ..|..|.|.|||.  |
ISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQP

RY--------CNAEIYEFMLYCWNIDATLRPKFTECKDFCKSL
 .        | .|.|. |. ||. |.  || |.|.   .. .
PNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF
Kinase kin-30.AA TK 133-451 21 4.5e-104 349.85 In-house 1-486 (486) Show / Hide 
Range on Protein: 133-451
Range on HMM: 1-486/486
Sequence Identity: 21% (108 aa)

DVFEKQFGQGNFG---KVNKALLKLINQ-------------------KTGEVVRMDVAVKKPADSTDKSQDKL--------------ILDEIKLMCA-IG
 ...|. |.|.||   .| |.... .|                    |.|....  |...|. |.... . ..               . |.|.||. .|
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

KHPNVLAIVGAITKQEKV------IGREHNLVVTEFVEGGD----LRSVLKYTPYTFHDELT------------------------STDRTGGQMVN---
.|||.. ..|..|..| .      ...|. ..|.|....||    ||. |.  . .|..|.                         |....... ..   
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC-PEEQD

------SDIFDELSTSDLYS-------------------FAYQIANGMEYLAAKPVRFFWGKSGANFQFLKKSEFPKCVHRDLALRNVFVKRNKM-----
      .|....|.|.||..                   ...|||.|||||..|... |              . ...|||||| ||. | .|.      
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCE-F--------------I-QNFVHRDLAARNCLVGENNVCKWHF

------IRIGDFG--------LARHHSKKSYYRMQCNPDT----------------------PLPIFWLAPECFN---------ESKFTEMTDVWSYGVC
      ..|.|||        ||| . ....|. . ...|                       ||| |.||||.|         . |||. .||||.||.
DGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVL

LFELFSLG-ESPYKKLH-------NSPSYDVVHYLKKG--------------YRLSAPRYCN--------------AEIYEFMLYCWNIDATLRPKFTEC
..|.|..| | .|  ..       . .  .|. ||..|              .|. .| .|               .|.|..|. ||. |.  || |...
MWEIFTYGQEPYYGGMSNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQL

KDFC
... 
HEQL
Kinase kin-30.AA TK-Unique 134-451 28 2.8e-66 226.52 In-house 2-294 (294) Show / Hide 
Range on Protein: 134-451
Range on HMM: 2-294/294
Sequence Identity: 28% (95 aa)

VFEKQFGQGNFGKVNKALLKLINQKTGEVVRMDVAVKKPADSTDKSQDKLILDEIKLMCAIGKHPNVLAIVGAITKQEKVIGREHNLVVTEFVEGGDLRS
..... |.|.|| | .. .. |.  ...  .  ||||.  |. .. ...  |.||..| ..|.|||.. ..|. || .     |  . . |....|.|..
EVGDVIGEGAFGQVWRGEVWGIW--KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD-----EPWMIIMEYCPCGNLQH

VLKYTPYT---------FHDELTSTDRTGGQMVNSDIFDE-LSTSDLYSFAYQIANGMEYLAA--KPVRFFWGKSGANFQFLKKSEFPKCVHRDLALRNV
 |... ..                    .  ..... ..| .|  |||.||.|||.||||||   | .                      |||||. |||
YLRTCRPAMRQHQTYGNLK--------FDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKI----------------------VHRDLCARNV

FVKRNKMIRIGDFGLARHHSKKSYYRMQCNPDTPLPIFWLAPECFN--ESKF-TEMTDVWSYGVCLFELFSLGESPYKKLHNSPSYDVVHYLKKGYRLSA
.. ..|.. |.|||.||. ..   | |.|    ..|| |.||| .   .  . |. .||||.|| ..|.|.||. || .. ..    ..  ...|||.  
LLTEDKVCKICDFGMARDVYTNGVYSMMC-SQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKD---IMECIRDGYRMPQ

PRYC-NAEIYEFMLYCWNIDATLRPKFTECKDFC
| .| . |.|..| .||. ... || |...|.  
PEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase kin-30.AA Pkinase_Tyr 310-451 43 5.9e-61 207.06 Pfam 131-270 (270) Show / Hide 
Range on Protein: 310-451
Range on HMM: 131-270/270
Sequence Identity: 43% (62 aa)

KCVHRDLALRNVFVKRNKMIRIGDFGLARHHSKKSYYRMQCNPDTPLPIFWLAPECFNESKFTEMTDVWSYGVCLFELFSLGESP-YKKLHNSPSYDVVH
.|.||||| ||. |..|. ..|.|||||| . ...|| ..   ...|||.|.||||.|..|||. .||||.||...|.|..||.| |. . |   ..|..
NCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSN---EEVYE

YL-KKGYRLSAPRYCNAEIYEFMLYCWNIDATLRPKFTECKDFC
|. ..|||. .|..| .|||. |. ||. |.  || |.|.  . 
YIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase kin-30.AA Ack 311-451 36 1.5e-42 141.34 In-house 126-266 (266) Show / Hide 
Range on Protein: 311-451
Range on HMM: 126-266/266
Sequence Identity: 36% (52 aa)

CVHRDLALRNVFVKRN-KMIRIGDFGLARH-HSKKSYYRMQCNPDTPLPIFWLAPECFNESKFTEMTDVWSYGVCLFELFSLGESPYKKLHNSPSYDVVH
|.||||| ||. . .  ... |.|||| |     . ||||. ..  ..|. | |||| .  .|.   |||..||.| | || || |.. .   . |.. .
CIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMFGVTLWEMFSYGEEPWAGC---NGYQILQ

YLK-KGYRLSAPRYCNAEIYEFMLYCWNIDATLRPKFTECKDFC
 .  .| ||  | .|  .||. |. ||  ..  ||.| . .|. 
KIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL
Kinase kin-30.AA EGFR 312-452 40 7.1e-41 133.33 In-house 123-258 (258) Show / Hide 
Range on Protein: 312-452
Range on HMM: 123-258/258
Sequence Identity: 40% (58 aa)

VHRDLALRNVFVKRNKMIRIGDFGLAR--HHSKKSYYRMQCNPDTPLPIFWLAPECFNESKFTEMTDVWSYGVCLFELFSLGESPYKKLHNSPSYDVVHY
|||||| ||| ||  . ..| |||||.  .| .|.|          .|| |.| ||. . ..|   ||||||| . ||   |..||. .   |  ..   
VHRDLAARNVLVKSPNHVKITDFGLAKLLEHDEKEYHAQGGK----MPIKWMALECIHHRCYTHQSDVWSYGVTCWELMTFGQKPYDGI---PAREIPDL

LKKGYRLSAPRYCNAEIYEFMLYCWNIDATLRPKFTECKDFCK
|.|| ||. |  |   .|  |. || ||.  ||.| |     |
LEKGERLPQPPICTIDVYMVMVKCWMIDEDMRPTFKELYEEFK
Kinase kin-30.AA UTK 310-451 30 3.2e-39 131.82 In-house 138-296 (296) Show / Hide 
Range on Protein: 310-451
Range on HMM: 138-296/296
Sequence Identity: 30% (49 aa)

KCVHRDLALRNVFVKRN-------KMIRIGDFG---LARHHS-------KKSYYRMQCNPDTPLPIFWLAPECFNES-KFTEMTDVWSYGVCLFELFSLG
..|||||| ||..| ..         ..|.|||   ..|  .        ...|  . ......|| | |||....  .||. .||||.|| ..|... |
GFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWG

ESPYKKLHNSPSYDVVHYLKKG--YRLSAPRYCNAEIYEFMLYCWNIDATLRPKFTECKDFC
  ||. . |    .|.| . .|  ||. .|. | ...|. |. ||. |   || | .  .. 
RLPYPGMSNM---QVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase kin-30.AA FGFR 310-451 40 2.8e-36 121.11 In-house 156-293 (293) Show / Hide 
Range on Protein: 310-451
Range on HMM: 156-293/293
Sequence Identity: 40% (58 aa)

KCVHRDLALRNVFVKRNKMIRIGDFGLARHHSKKSYYRMQCNPDTPLPIFWLAPECFNESKFTEMTDVWSYGVCLFELFSLGESPYKKLHNSPSYDVVHY
||.||||| ||| |  .  . | ||||||   .  |||   |    ||| | |||   . ..|   ||||||| | | . .|..||      .  .   |
KCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRKTTN--GRLPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVE--ELYKY

LKKGYRLSAPRYCNAEIYEFMLYCWNIDATLRPKFTECKDFC
|| |.|.  |  |  |||  |  ||   .  || |..  .  
LKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase kin-30.AA RTKB 312-451 39 6.3e-36 118.6 In-house 131-264 (264) Show / Hide 
Range on Protein: 312-451
Range on HMM: 131-264/264
Sequence Identity: 39% (55 aa)

VHRDLALRNVFVKRNKMIRIGDFGLARHHSKKSYYRMQCNPDTPLPIFWLAPECFNESKFTEMT-DVWSYGVCLFELFSLGESPYKKLHNSPSYDVVHYL
.||||. ||| |  .   .| |||.||  ..   |.  |   | ||| |.|||   .. .|    ||||.||  .| ||||  ||... |    |.  .|
IHRDLCARNVLVDQQLHCKICDFGMAR-EIDHECYETTC---TRLPIKWMAPESWAHRIYTTKSGDVWSFGVTMWEIFSLGGTPYQQYRN---GDIFYWL

KKGYRLSAPRYCNAEIYEFMLYCWNIDATLRPKFTECKDFC
 .|.||  ||  ...... |  || ..|  || |.|  |  
ESGHRLPKPRQMPQAADHIMQMCWQMEAQHRPDFDELVDAF
Kinase kin-30.AA Fer 310-452 32 1.6e-32 108.1 In-house 131-283 (283) Show / Hide 
Range on Protein: 310-452
Range on HMM: 131-283/283
Sequence Identity: 32% (50 aa)

KCVHRDLALRNVFVKRNKMIR---IGDFGLARHHS--KKSYYRMQCNPDTPLPIFWLAPECFNESKFTEMTDVWSYGVCLFELFSLGESPYKK------L
.|.|||.| ||. .  .|      | |||..|. |  ...|.     . . .|| |||||...   ....|||||.|| ..| |. |. ||        .
NCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKE--KACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKM

HNSPSYDVVHYLKKGYRLSAPRYCNAEIYEFML-YCWNIDATLRPKFTECKDFCK
 | . ...  . ||||..  |  .  ||...|.  ||. |   ||...| .   |
TNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase kin-30.AA VEGFR 310-450 44 8.7e-32 111.93 In-house 193-332 (332) Show / Hide 
Range on Protein: 310-450
Range on HMM: 193-332/332
Sequence Identity: 44% (65 aa)

KCVHRDLALRNVFVKRNKMIRIGDFGLARH--HSKKSYYRMQCNPD-TPLPIFWLAPECFNESKFTEMTDVWSYGVCLFELFSLGESPYKKLH-NSPSYD
||.||||| ||. .  |. . | |||||||   .   | |     | . ||| |.|||   .  .|   ||||||| | | |||| |||     .    .
KCIHRDLAARNILLCENNVVKICDFGLARHGIYKDPDYVRKG---DQGRLPIKWMAPESIFDKVYTTYSDVWSYGVFLWEIFSLGGSPYPGVQIDE---E

VVHYLKKGYRLSAPRYCNAEIYEFMLYCWNIDATLRPKFTE-CKDF
    || |||. || ||. |||. || ||  .   || | |  . .
FCNRLKDGYRMRAPDYCTPEIYHIMLDCWHKEPEERPHFSELVEHL
Kinase kin-30.AA Pkinase_Tyr 134-288 26 9.6e-32 108.14 Pfam 2-131 (270) Show / Hide 
Range on Protein: 134-288
Range on HMM: 2-131/270
Sequence Identity: 26% (42 aa)

VFEKQFGQGNFGKVNKALLKLINQKTGEVVRMDVAVKKPADSTDKSQ--DKLILDEIKLMCAIGKHPNVLAIVGAIT-KQE-KVIGREHNLVVTEFVEGG
.| |. |.|.||.| |. .|      ..  ...||||.  ......|   .  . |.|.|. .|.|||..  .|..| ..| .     . ..|.|....|
TFGKKLGEGAFGEVYKGTWKG----DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-----QIYIVMEYMPHG

DLRSVLKYTPYTFHDELTSTDRTGGQMVNSDIFDELSTSDLYSFAYQIANGMEYLAAKP
||.. |.                       .  . |...|| ....|||.|||||..|.
DLLDYLRKHR--------------------EDKQPLTMKDLLQMCWQIAKGMEYLESKN
Kinase kin-30.AA Pkinase 134-448 19 2e-24 87.48 Pfam 2-288 (293) Show / Hide 
Range on Protein: 134-448
Range on HMM: 2-288/293
Sequence Identity: 19% (70 aa)

VFEKQFGQGNFGKVNKALLKLINQKTGEVVRMDVAVKK-PADSTDKSQDKLILD--EIKLMCAIGKHPNVLAIVGAITKQEKVIGREHNLVVTEFVEGG-
..... |.|.||.| |.  |  ..         ||||. . .......|.  .   ||..|  . .|||.. . .. .       . |  .|.|..||| 
HIGRKIGSGSFGCVYKCHHKGTGK--------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED------KDHIYMVMEYCEGGL

---DLRSVLKYTPYTFHDELTSTDRTGGQMVNSDIFDELSTSDLYSFAYQIANGMEYLAAKPVRFFWGKSGANFQFLKKSEFPKCVHRDLALRNVFVKRN
   || ....                     ..  |  .|  .. ...|||. |.||. ..                      ...|||| . |.....|
YVMDLFDYIST-------------------WRHGCFY-FSEWECKFYMYQILRGLEYCHSM----------------------GIIHRDLKPENILIDNN

KMI----RIGDFGLARH--HSKKSYYRMQCNPDTPLPIFWLAPECFN-ESKFTEMTDVWSYGVCLFELFSLGESPYKKL---HNSPSYDVVHYLKKGYRL
  |    .|.|||||..  . ..| .   |       ....|||  .  .. .   |.||.|. |.|... |. |..     .|  . ........| .|
GHIDACVKICDFGLAKQFDY-NNS-MTTFC-----GTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPL

SAPRY--CN-------------------AEIYEFMLYCWNIDATLRPKFTECK
. ...  |.                    |  .|. .|.. | . || .....
HFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL
Kinase kin-30.AA S_TKc 133-455 19 4.7e-16 58.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 133-455
Range on HMM: 1-231/231
Sequence Identity: 19% (65 aa)

DVFEKQFGQGNFGKVNKALLKLINQKTGEVVRMDVAVKKPADSTDKSQDKLILDEIKLMCAIGKHPNVLAIVGAITKQEKVIGREHNLVVTEFVEG--GD
  . .. |.| |||| |.  |             ||.|.          . |. ||...    .|||.  . ...         .|  .|.|...|  ||
YEILRKIGKGAFGKVYKCRHKK--------TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGD

LRSVLKYTPY-----TFHDELTSTDRTGGQMVNSDIFDELSTSDLYSFAYQIANGMEYLAAKPVRFFWGKSGANFQFLKKSEFPKCVHRDLALRNVFVKR
|....|  ..      |.   .                        ...|||....||.  . .                      .||||   |... .
LFDYIKKRGRHGLRFPFPE-HAR-----------------------FYMYQICCALEYCHSHGI----------------------IHRDLKPENILLDE

NKMIRIGDFGLARHHSKKSYYRMQCNPDTPLPIFWLAPECFNESKFTE-MTDVWSYGVCLFELFSLGESPYKKLHNSPSYDVVHYLKKGYRLSAPRYCNA
   | |.||||||.                   ...||| .   ...    |.|| |..|.|... |. |.         ..   .||            
--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--------QMQMMFKKIG--------SP

EIYEFMLYCWNIDATLRPKFTECKD-----FCKSLI
|  .|.  |.. | . ||   |.        |   .
EAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase kin-30.AA UTK 135-285 29 6.9e-16 50.83 In-house 3-135 (296) Show / Hide 
Range on Protein: 135-285
Range on HMM: 3-135/296
Sequence Identity: 29% (47 aa)

FEKQFGQGNFGKVNKALLKLINQKTGEVVRMDVAVKKPADSTDKSQDKL----ILDEIK---LMCAIGKHPNVLAIVGAITKQEKVIGREHNLVVTEFVE
. .| |||.|| |.|| .. ..   . .  ||||||.   . |. |..     .. | .   .| .   |||||  ||  |..|        ..|||. |
LGRQLGQGAFGEVHKARFTQCS---EHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP------WMIVTEYME

GGDLRSVLKYTPYTFHDELTSTDRTGGQMVNSDIFDELSTSD-LYSFAYQIANGMEYLA
.|||||.| . . |.                  ..... |.. . ..|..||.||.||.
NGDLRSYLRRHRPTPP-----------------ACPHWLTLHQRLCMAWDIARGMQYLH
Kinase kin-30.AA Fer 134-236 33 4.3e-13 41.03 In-house 2-101 (283) Show / Hide 
Range on Protein: 134-236
Range on HMM: 2-101/283
Sequence Identity: 33% (36 aa)

VFEKQFGQGNFGKVNKA--LLKLINQKTGEVVRMDVAVKKP-ADSTDKSQDKLILDEIKLMCAIGKHPNVLAIVGAITKQEKVIGREH-NLVVTEFVEGG
...|. | |.||.| |.   ||....|. .|.  .|.|||  .....| | | .. | ..|    .|||| .. |       |.  |.  ..| ||. ||
TLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYG-------VCVDEQPIMIVMEFCNGG

DLRSVLK
.|.| ||
SLDSYLK
Kinase kin-30.AA FGFR 260-287 50 1.6e-07 21.63 In-house 128-155 (293) Show / Hide 
Range on Protein: 260-287
Range on HMM: 128-155/293
Sequence Identity: 50% (14 aa)

DIFDELSTSDLYSFAYQIANGMEYLAAK
..  .|.  || |.|||.| |||||| .
ELIPNLTQKDLVSCAYQVARGMEYLASR
Kinase kin-30.AA RTKB 135-205 30 1.8e-07 21.31 In-house 3-69 (264) Show / Hide 
Range on Protein: 135-205
Range on HMM: 3-69/264
Sequence Identity: 30% (22 aa)

FEKQFGQGNFGKVNKALLKLINQKTGEVVRMDVAVKKPADSTDKSQDKLILDEIKLMCAIGKHPNVLAIVG
  .. |.| || | .|...  |. ...  .  . | ||. |  . ||  ...|. .| ..| ||||. |.|
LGEKLGNGAFGEVFQAWVR--NRHMNTEQSCAAKVLKPGASYEERQD--FCSEMTVMKELGWHPNVIGIIG
Kinase kin-30.AA EGFR 136-205 31 4e-06 15.99 In-house 4-68 (258) Show / Hide 
Range on Protein: 136-205
Range on HMM: 4-68/258
Sequence Identity: 31% (22 aa)

EKQFGQGNFGKVNKALLKLINQKTGEVVRMDVAVKKPADSTDKSQDKLILDEIKLMCAIGKHPNVLAIVG
 |  | | ||.| | .   | .  || |.  ||.|   ..|.... . .||| . |  . .||... ..|
VKVLGSGAFGTVYKGI--WIPE--GENVKIPVAIKVLREQTGPKANEEMLDEAYVMASV-DHPHLVRLLG
Kinase kin-30.AA VEGFR 265-287 43 6e-06 18.62 In-house 170-192 (332) Show / Hide 
Range on Protein: 265-287
Range on HMM: 170-192/332
Sequence Identity: 43% (10 aa)

LSTSDLYSFAYQIANGMEYLAAK
| . || ....|.|.|||.|| .
LTMEDLICYSFQVARGMEFLASR
Kinase kin-30.AA VEGFR 137-212 30 1.5e-05 17.13 In-house 5-79 (332) Show / Hide 
Range on Protein: 137-212
Range on HMM: 5-79/332
Sequence Identity: 30% (24 aa)

KQFGQGNFGKVNKALLKLINQKTGEVVRMDVAVKKPADSTDKSQDKLILDEIKLMCAIGKHPNVLAIVGAITK--QEK
|. |.| ||.| .|  . |.   .  .   ||||.     . |  .  . |.|..  ||.| ||    |. ||  | .
KMLGRGAFGQVHEASAFGIRKMETCTT---VAVKMLKEGATASEHRALMSELKMLIHIGHHLNVVNFLGCCTKNIQKG
Kinase kin-30.AA FGFR 134-206 32 0.000297 10.34 In-house 2-73 (293) Show / Hide 
Range on Protein: 134-206
Range on HMM: 2-73/293
Sequence Identity: 32% (24 aa)

VFEKQFGQGNFGKVNKALLK-LINQKTGEVVRMDVAVKK-PADSTDKSQDKLILDEIKLMCAIGKHPNVLAIVGA
.  |  | | ||.| .|  | . .... . .   ||||.  .. |||    |.  |.  |  ||||.|..   |.
TLGKMLGEGCFGQVWMAEAKGIDCDRPEKEIT--VAVKMLKMNHTDKDLSDLV-SEMEMMKMIGKHKNIINLLGC
Kinase kin-30.AA RTKB 265-289 40 0.002467 7.12 In-house 106-130 (264) Show / Hide 
Range on Protein: 265-289
Range on HMM: 106-130/264
Sequence Identity: 40% (10 aa)

LSTSDLYSFAYQIANGMEYLAAKPV
|. . | .|. |||.|| .|  . |
LKQAQLVDFCHQIACGMAFLHQHNV
Kinase kin-30.AA Fer 263-289 35 0.002858 7.12 In-house 105-132 (283) Show / Hide 
Range on Protein: 263-289
Range on HMM: 105-132/283
Sequence Identity: 35% (10 aa)

DE-LSTSDLYSFAYQIANGMEYLAAKPV
.. .|. ..  ..||.|.||||| .| .
NKTVSDNEKIRMCYQAACGMEYLHSKNC
Kinase kin-30.AA Ack 270-287 55 0.004774 6.13 In-house 107-124 (266) Show / Hide 
Range on Protein: 270-287
Range on HMM: 107-124/266
Sequence Identity: 55% (10 aa)

LYSFAYQIANGMEYLAAK
|  |. |||.|| || .|
LCDFCMQIAMGMRYLEMK
Kinase kin-30.AA EGFR 263-284 40 0.029361 3.1 In-house 96-117 (258) Show / Hide 
Range on Protein: 263-284
Range on HMM: 96-117/258
Sequence Identity: 40% (9 aa)

DELSTSDLYSFAYQIANGMEYL
|..   .|  ...||| ||.||
DNIGSQHLLNWCVQIAKGMQYL