Gene kin-5 (Nematode worm)

kin-5

Species: Nematode worm
Alias: T13H10.1, aSWK370, kin-5, CE06444
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: IV: 9969043-9967083, WormBase Genetic Map location: n/a,

Classification

Group: TK
Family: Fer

Sequence

Name Sequence Type Origin Length Description Download
kin-5.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 255 Kinase domain by global Sugen HMM Fasta, JSON
kin-5.AA Protein Genbank 533 None Fasta, JSON

Protein domain

Protein domains of kin-5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 kin-5.AA SH2 14-98 34 1.4e-29 105.53 SMART 1-87 (87) Show / Hide 
Range on Protein: 14-98
Range on HMM: 1-87/87
Sequence Identity: 34% (32 aa)

EPWYHGLLPREDMKQLLTQR----GDFLVRFTDPKVGEPRKFVLSVYVGVIEDIRHYVIREHN-NKFAVDK---KWFSSIADLLNYYHRSKEP
.||||| ..||.  ||| ..    ||||||. ..   .|...|||| ..  . ..||.||. . .|. .|    ..|.|. .|.|.|.. . .
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES---NPGDYVLSVRWK--GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 kin-5.AA SH2 16-92 28 6.6e-23 69.07 Pfam 1-81 (81) Show / Hide 
Range on Protein: 16-92
Range on HMM: 1-81/81
Sequence Identity: 28% (24 aa)

WYHGLLPREDMKQLLTQ----RGDFLVRFTDPKVGEPRKFVLSVYVGV-IEDIRHYVIREHNNK--FAVDKKWFSSIADLLNYY
|||| ..|..  .|| .    .|.||||. . . |.   ..|||. .  .. ..||.|....|.  .  ... |.|...| ..|
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGD---YTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
Kinase kin-5.AA Fer 123-377 48 9.20000000001e-149 500.51 In-house 1-283 (283) Show / Hide 
Range on Protein: 123-377
Range on HMM: 1-283/283
Sequence Identity: 48% (137 aa)

VTLIKKLGEGAFGEVQLG--EIRIGN----TVKKAAIKLAKL--ESLTKEQIKEIMHEARLMRK-FKHPNVVTFYGVAAGQEPLMVIMELADNGALDSYL
|||.||||||||||| .|  ......    .| |.|.| .|.  |..|||||||.|||||.||. ..||||| ||||.. ..|.|..||....|.|||||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

KKNIG-SLPISKKHTMVLQAGLGLEYLHSLQIIHRDIASRNCLYGNGQVK----ISDFGLSRE----GYSYRMN-PHKKVPIRWLAPEVPRTGFYTPKTD
||| . .... .|. |..||  |.||||| ..||||||.|||||....||    |||||.||.    ||.|.|  ...||||||||||. .||.|.||||
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VFAYGVMCWEVYHDGIEPYPG----MKVAEV----LPR-VQNGYRMPFEANVPPAIVRFITYRICAGAEEERVTMSEAVRELL
|...||||||....| |||||    ||...|      . ...||.||.. ..||.|.......... . |.| ||.|....| 
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase kin-5.AA TyrKc 123-376 37 1.2e-113 384.75 SMART 1-280 (280) Show / Hide 
Range on Protein: 123-376
Range on HMM: 1-280/280
Sequence Identity: 37% (110 aa)

VTLIKKLGEGAFGEVQLGEIRIGNTVKKAAIKLAKLESLTKEQIKEIMHEARLMRKF--KHPNVVTFYGVAAGQ-------EPLMVIMELADNGALDSYL
.||.||||||||||| .|. .      . |.|  | ..     ....|.|||.|.|.  .|||.| .|||.  |       ||||..||....|.|..||
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KKNIGSLPISKKHTMVLQAGLGLEYLHSLQIIHRDIASRNCLYGNGQ-VKISDFGLSREGYSY--------RMNP----HKK--VPIRWLAPEVPRTGFY
.|. . |. .... . .|.  | ||||| ..||||.| ||||.|... ||||||||||..|..           .    ..|  .||||.|||. ..| .
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TPKTDVFAYGVMCWEVYHDGIEPYPG-----MKVAEVLPRVQNGYRMPFEAN--------VPPAIVRFITYRICAGAEEERVTMSEAVREL
|.|.||...||..||.. .| .||||     |. .||. .|..|||||  .|         |... . |  . ..   |.| |.|| ....
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase kin-5.AA Pkinase_Tyr 123-341 41 2.1e-91 310.19 Pfam 1-236 (270) Show / Hide 
Range on Protein: 123-341
Range on HMM: 1-236/270
Sequence Identity: 41% (98 aa)

VTLIKKLGEGAFGEVQLGEIR--IGNTVKKAAIKLAKLESLTKEQ--IKEIMHEARLMRKF-KHPNVVTFYGVAA-GQEP--LMVIMELADNGALDSYLK
.|..||||||||||| .|. .   .||  . |.|    |. ..||  ... |.||..|... .|||.| .|||    .||  ....||.. .| |..||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KN---IGSLPISKKHTMVLQAGLGLEYLHSLQIIHRDIASRNCLYG-NGQVKISDFGLSREG-----YSYRMNPHKKVPIRWLAPEVPRTGFYTPKTDVF
|.    ..|... .  | .|   |.|||.| ..||||.| |||| . |..|||.||||.|       | ||.  . |.||.|.|||. ..| .| |.|| 
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVW

AYGVMCWEVYHDGIEP-YPGMKVAEVLPRV-QNGYRMP
..|| .||..  | .| ||||. .||. .. ..|||||
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMP
Kinase kin-5.AA TK 123-376 21 3.6e-89 299.02 In-house 1-486 (486) Show / Hide 
Range on Protein: 123-376
Range on HMM: 1-486/486
Sequence Identity: 21% (107 aa)

VTLIKKLGEGAFG---EVQLGEIRIGN-----------------------TVKKAAIKLAKLE--SLTKEQIKEIMH----------EARLMRKFK----
.||.||||||.||   || .|| | .|                       .. . |.|  |..  .  .|.. |.||          ||. | ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNVVTFYG-------------VAAGQEPLMVIMELADNGA----LDSYLKKNIGS-------------------------------------------
 |||.| .||             |  .|||.|..||....|     |..||.|. .                                            
HHPNIVRLYGVCTQGEPKPCFEVV-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD

--------------------------------LPISKKHTMVLQAGLGLEYLHSL------QIIHRDIASRNCLYGNGQ------------VKISDFG--
                                |.   .. | .|.  |.|||||.      ...|||.| |||| |..             .||.|||  
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LSREGYS----YRMNPHK-----------------------KVPIRWLAPEVPRTGF---------YTPKTDVFAYGVMCWEVYHDGIEPYPG-
      |.|. ||    ||.....                       |.||||.|||. ...          .|.|.||...||..||..  | |||.| 
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

MKV---------AEVLPRVQNG--------------YRMPFEANVPP-------------AIVRFITYRICAGAEEERVTMSEAVREL
|           .||. ....|              .|||  .. |.             ...  .  . ..   |.| |.|. ...|
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase kin-5.AA UTK 123-352 32 1.1e-68 234.07 In-house 1-273 (296) Show / Hide 
Range on Protein: 123-352
Range on HMM: 1-273/296
Sequence Identity: 32% (90 aa)

VTLIKKLGEGAFGEVQLGEIRIGN---TVKKAAIKLAKLESLTKEQIK---EIMHEAR---LMRKFK-HPNVVTFYGVAAGQEPLMVIMELADNGALDSY
| | ..||.||||||.... .  .   .. . |.| .. .. .  .     ..| |||   .| .|. ||||. ..||   .||.|...|.. || |.||
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LKKNIGSLP----ISKKHT---MVLQAGLGLEYLHSLQIIHRDIASRNCLYGNG--------QVKISDFG---LSREGY------------SYRMNPHKK
| ..  ..|    . ..|.   |...   |..|||| ...|||.| |||| .          ..||.|||   .||. .             |.... ..
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

VPIRWLAPEVPRTG-FYTPKTDVFAYGVMCWEVYHDGIEPYPGMKVAEVLPRVQNG--YRMPFEANVPPAIVR
.|||| |||.   .  .| |.||...|| |||... |  |||||  ..|. .| ||  ||||  . .| .. |
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYR
Kinase kin-5.AA Src 123-350 37 1e-49 167.1 In-house 1-229 (255) Show / Hide 
Range on Protein: 123-350
Range on HMM: 1-229/255
Sequence Identity: 37% (89 aa)

VTLIKKLGEGAFGEVQLGEIRIGNTVKKAAIKLAKLESLTKEQIKEIMHEARLMRKFKHPNVVTFYGVAAGQEPLMVIMELADNGALDSYLK-KNIGS-L
..|..|||.| ||||  |  . |||  | |.|  |  ..  |.      || .| |..|...|  | |    ||   . |.  .| |  ||| .  |. |
IKLCRKLGQGQFGEVWMGYWN-GNT--KVAVKTLKPGTMSPEAFL---QEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHL

PISKKHTMVLQAGLGLEYLHSLQIIHRDIASRNCLYGNGQ-VKISDFGLSREGY----SYRMNPHKKVPIRWLAPEVPRTGFYTPKTDVFAYGVMCWEVY
.. .   |  |   | .|| | ..|||| | || | |..  .|. |||| |        | .    |.||.| |||  . | .| |.||  .|.  .|. 
HLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIV

HDGIEPYPGMKVAEVLPRVQNGYRMPFEANVPPAI
  |  |||||. .||| .|..|||||  .|.|. .
TYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDEL
Kinase kin-5.AA Ack 123-341 34 1.1e-45 152.11 In-house 1-232 (266) Show / Hide 
Range on Protein: 123-341
Range on HMM: 1-232/266
Sequence Identity: 34% (79 aa)

VTLIKKLGEGAFGEVQLGEIRI-GNTVKKAAIKLAKLESLTKE-QIKEIMHEARLMRKFKHPNVVTFYGVAAGQEPLMVIMELADNGALDSYLKKNIG--
.|| .|||.| || |. ||    |...   |.|  . . ..    . . . |.  | .  ||..|  |||  .|  || ..|||  |.|   |.|  .  
ITLCEKLGDGCFGVVWRGEWTNPGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVVLDQPMLMMVTELAPCGSLLDCLRKHCRTA

SLPISKKHTMVLQAGLGLEYLHSLQIIHRDIASRNCLYGNG--QVKISDFGLSR---EGYS-YRMNPHK--KVPIRWLAPEVPRTGFYTPKTDVFAYGVM
 ..|.  .   .|   |. ||..  .|||| | || |   .   |||.||||.|   ..   |||..|.  |||. | |||  |..  . . || ..|| 
FFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMFGVT

CWEVYHDGIEPYPGMKVAEVLPRVQ-NGYRMP
 ||.   | ||. |.  ...| ..  .| | |
LWEMFSYGEEPWAGCNGYQILQKIDKEGERLP
Kinase kin-5.AA Frk 123-350 35 9.6e-45 152.85 In-house 1-231 (260) Show / Hide 
Range on Protein: 123-350
Range on HMM: 1-231/260
Sequence Identity: 35% (84 aa)

VTLIKKLGEGAFGEVQLGEIRIGNTVKKAAIKLAKLESLTKEQIKEIMHEARLMRKFKHPNVVTFYGVAAGQEPLMVIMELADNGALDSYLK---KNIGS
. ||..|| | ||||  |     |     |.|  |  ..     .. . ||..|.| .|| ..  | | . .||...| ||  .|.|  ||.   ..  .
IQLIRRLGSGQFGEVWEGLW---NNTTPVAVKTLKPGTM---DPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQ

LPISKKHTMVLQAGLGLEYLHSLQIIHRDIASRNCLYGNGQ-VKISDFGLSR----EGY-SYRMNPHKKVPIRWLAPEVPRTGFYTPKTDVFAYGVMCWE
. . .   |  |   |. || |   ||||.| || | |... .|| |||| |    .    |      ..||.| |||  ..  .| | ||...|..  |
CQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTE

VYHDGIEPYPGMKVAEVLPRVQNGYRMPFEANVPPAI
.   |  |||||  ||||  |..|||||  .| |. .
IITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQL
Kinase kin-5.AA TKL 129-315 22 4.3e-44 152.81 In-house 1-283 (364) Show / Hide 
Range on Protein: 129-315
Range on HMM: 1-283/364
Sequence Identity: 22% (65 aa)

LGEGAFGEVQLGEIRI------GNTVKKAAIKLAKLESLTKEQI-------------------------KEIMHEARLMRKFKHPNVVTFYGVAAGQEP-
.|.|.||||  |. |       ..| |  |.|  | ..  .. .                         ...  |...|....|||.| |.|..   .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LMVIMELADNGALDSYLKKNIGSLPISKKHTMVLQAGLGLEYLHSLQ--------IIHRDIASRNCLYG-NGQ--------------V
            |. .||....| | .||        ..... ..|.. .|..|||| .        |||||. |.|.|   |..              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KISDFGLSREGY---SYRMN----------------PHKKV-PIRWLAPEV-----PRTGF-----------YTPKTDVFAYGVMCWEVY
||.||||||.     .  ..                 ....  .||.||||     . |             |..|.||...|.. ||..
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEIL
Kinase kin-5.AA Src-Echino1 123-341 37 3.3e-43 147.62 In-house 1-217 (252) Show / Hide 
Range on Protein: 123-341
Range on HMM: 1-217/252
Sequence Identity: 37% (84 aa)

VTLIKKLGEGAFGEVQLGEIRIGNTVKKAAIKLAKLESLTKEQIKEIMHEARLMRKFKHPNVVTFYGVAAGQEPLMVIMELADNGALDSYLKKNIGS-LP
. . ||.|.| .|||  | .  |||  . |.|  | .....    . . || .|.| .| ..| .| | . .||. .. ||  || | .|||.. .  . 
LRMDKKIGKGHCGEVWKG-VWNGNT--PVAVKTLKEKTMSPA---DFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVK

ISKKHTMVLQAGLGLEYLHSLQIIHRDIASRNCLYGNGQV-KISDFGLSR--EGYSYRMNPHKKVPIRWLAPEVPRTGFYTPKTDVFAYGVMCWEVYHDG
...   |  .   |..|| |  ..|||.| || | |.| | || |||| |  .   |  .   |.||.| |||    | .| | ||...|..  |.   |
MTTLIDMGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFG

IEPYPGMKVAEVLPRVQNGYRMP
  |||||.  ||| .|..|||||
RYPYPGMMNREVLDQVDRGYRMP
Kinase kin-5.AA Pkinase 123-324 26 1.1e-37 134.38 Pfam 1-214 (293) Show / Hide 
Range on Protein: 123-324
Range on HMM: 1-214/293
Sequence Identity: 26% (59 aa)

VTLIKKLGEGAFGEVQLGEIRIGNTVKKAAIKLAKLESLTKEQIKEIMH--EARLMRKFKHPNVVTFYGVAA-GQEPLMVIMELADNG----ALDSYLK-
 ....|.|.|.||.| ..  .  .   . |.|  |...  ... ..  .  |...|....|||.|..|..   ....  ..||....|     | .|.. 
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYIST

KNIGSL--PISKKHTMVLQAGLGLEYLHSLQIIHRDIASRNCLYG-NGQV----KISDFGLSRE--GYSYRMNPHKKVPIRWLAPEVPR-TGFYTPKTDV
.. |..  .      ...|   ||||.||  |||||. . |.|.  ||..    ||.||||..     ... . .  . ....|||| |    |.|| |.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

FAYGVMCWEVYHDGIEPYPG
...|....|..  |  |.||
WSCGCILYEMLC-GRPPFPG
Kinase kin-5.AA TK-Unique 235-376 34 3.8e-36 122.19 In-house 143-294 (294) Show / Hide 
Range on Protein: 235-376
Range on HMM: 143-294/294
Sequence Identity: 34% (53 aa)

GLEYLHS--LQIIHRDIASRNCL-YGNGQVKISDFGLSREGYS---YRMN-PHKKVPIRWLAPEVPR--TGFY-TPKTDVFAYGVMCWEVYHDGIEPYPG
|.|||.|   .|.|||...||.|  .....||.|||..|..|    | |.   ...||||.|||...  .| | |.|.|| ..||  ||.   |  ||||
GMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPG

MKVAEVLPRVQNGYRMPFEANV-PPAIVRFITYRICAGAEEERVTMSEAVREL
|. .... ....|||||  ... ....  .. .      .|||.. .. . .|
MPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKS-CWQWEPEERPSFRQIKHRL
Kinase kin-5.AA S_TKc 123-377 25 2.5e-34 121.26 SMART 1-231 (231) Show / Hide 
Range on Protein: 123-377
Range on HMM: 1-231/231
Sequence Identity: 25% (68 aa)

VTLIKKLGEGAFGEVQLGEIRIGNTVKKAAIKLAKLESLTKEQIKEIMHEARLMRKFKHPNVVTFYGVAAGQEPLMVIMELADN--GALDSYLKKNIGS-
 ....|.|.||||.| ..  .   | .. |||  |         . |. | ....| .|||.|..|.|    . | ..||..|.  | | .|.||. .  
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LPISKKHTMVLQAGLGLEYLHSLQIIHRDIASRNCLYGNGQVKISDFGLSREGYSYRMNPHKKVPIRWLAPEVPRTGFYTP-KTDVFAYGVMCWEV
    .|      .. |  ..|||.||..|||||.   | |  . ..||.||||.|.        .  .   ..||||     |.. | |. . |.. .| 
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

YHDGIEPYPGMKVAEVLPRVQNGYRMPFEANVPPAIVRFITYRICAGAEEERVTMSEAVR--------ELL
.  |  |.|   ..... ..             .  .. .  ...    |.| |  || .        . .
LC-GYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase kin-5.AA Tec 123-270 36 3.5e-31 106.25 In-house 1-145 (254) Show / Hide 
Range on Protein: 123-270
Range on HMM: 1-145/254
Sequence Identity: 36% (55 aa)

VTLIKKLGEGAFGEVQLGEIRIGNTVKKAAIKLAKLESLTKEQIKEIMHEARLMRKFKHPNVVTFYGVAAGQEPLMVIMELADNGALDSYLKKNIGSLPI
 |..| || | || |.||. |      . |||  |  |   |   . . ||. | |  ||. | .|||   | |. .. |   .| | .||... . .  
LTFMKELGSGQFGVVHLGKWRH---QYDVAIKMIKEGSMSEE---DFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQK

SK--KHTMVLQAGLGLEYLHSLQIIHRDIASRNCLYGNGQ-VKISDFGLSR
.      | ..   | .|| . . |||| | |||| |  . ||.||||..|
NMAILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTR
Kinase kin-5.AA TK-Unique 123-216 28 3.8e-20 66.26 In-house 1-99 (294) Show / Hide 
Range on Protein: 123-216
Range on HMM: 1-99/294
Sequence Identity: 28% (28 aa)

VTLIKKLGEGAFGEVQLGEIRIGN---TVKKAAIKLAKLESLTKEQIKEIMHEARLMRKFK-HPNVVTFYGVAA-GQEPLMVIMELADNGALDSYLKKN
... ...||||||.|  ||.. ..     .| ..  .  ...|... .. . |...|.. . |||.|...|.    .|| | ||| . .| |..||...
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTC
Kinase kin-5.AA Tec 282-340 42 1.1e-12 40.67 In-house 159-217 (254) Show / Hide 
Range on Protein: 282-340
Range on HMM: 159-217/254
Sequence Identity: 42% (25 aa)

KVPIRWLAPEVPRTGFYTPKTDVFAYGVMCWEVYHDGIEPYPGMKVAEVLPRVQNGYRM
| |..| .|||     |  | || |.||  |||.  |  ||. |.  ||  .|. |.|.
KFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRL