Gene lin-18 (Nematode worm)

lin-18

Species: Nematode worm
Alias: aSWK403, CE27692, C16B8.1, lin-18
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: X: 3962285-3965672, WormBase Genetic Map location: X:-8.82474,

Classification

Group: TK
Family: Ryk

Sequence

Name Sequence Type Origin Length Description Download
lin-18.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 289 Kinase domain by global Sugen HMM Fasta, JSON
lin-18.AA Protein Genbank 562 None Fasta, JSON

Protein domain

Protein domains of lin-18.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
WIF lin-18.AA WIF 1-128 44 6.4e-78 266.09 SMART 4-146 (146) Show / Hide 
Range on Protein: 1-128
Range on HMM: 4-146/146
Sequence Identity: 44% (63 aa)

MFISKEEMNRTFGVKAELNYIEMGNVSSYSTKF------HYRVMANIDYLSFTWNAVGI---VHYEVYVESDDSSVL--PIVRIPLKGTVPESLQDFTVE
|.|.|.||.|..||.|||.|...|....|...|      .|.|.|||.|..|||.|||.   |||...|.|||..|.  |||.||..||||..||...||
MWINKHEMRRLIGVDAELYYVREGHINHYAHNFRKAQQRMYPVPANIHYMHFTWQAVGQAHYVHYFINVQSDDQEVMPMPIVNIPHQGTVPHTLQVWQVE

YRCAGHRS--GQFAVSLYFTFKYG--NKEPLKVKLRQEKICAS
|.|.|||.  ..|.|..|...||.  .|.......|..|||..
YKCSGHRDGVAEFMVTMYVMVKYNRSTKNFTHLNFRRKKICYQ
WIF lin-18.AA WIF 1-126 26 1.3e-36 126.65 Pfam 1-145 (145) Show / Hide 
Range on Protein: 1-126
Range on HMM: 1-145/145
Sequence Identity: 26% (39 aa)

MFISKEEMNRTFGVKAELNYIEMGNVSSYSTK-----F------HYRVMANIDYLSFTWNA--VGIVHYEVYV-ESDDSSVL--PIVRIPLKGTVPESLQ
|.|........ || ||. ||. | |. |...     |       ..| .|. |..|||..      ||.  |  |.| ...  |...|...|.|| . .
MWINEHQVMMLIGVSAEIYYIHNGHVNHYAHDPNFSHFRKAQQRMPPVPSNVHYVNFTWQSLGKHKYHYNFQVLYSSDQQIMKRPTLNISHQGRVPHEAK

DFTVEYRCAGHRSGQFAVSLYFTFKYGNKEPLK---VKLRQEKIC
 | ....|.| ||||.....   ..  .. |..   . ....|||
EFSIDLPCSGNRSGQATFTVNLEVMHRRSKPNNNTPLRFKRKKIC
Kinase lin-18.AA Ryk 260-551 58 1.4e-240 768.85 In-house 1-292 (292) Show / Hide 
Range on Protein: 260-551
Range on HMM: 1-292/292
Sequence Identity: 58% (170 aa)

FQSLPLDMEGTFGEVRYAIWRQVDDVLNGDVDDEEDTFCNQEAVYTKTLKNNASPIQLDRFLSDALLFYNITPHQNLSQVACVASFGRFDRPETVTDFPL
.|...|..|||||.....||.|||||.||||||||||||....|..||.|..||..|....|....|.|.|.||||...|..|.||||||||....|.|.
IQYSCLVQEGTFGRIYHGIWNQVDDVNNGDVDDEEDTFCDCQDVFVKTVKDHASQMQVHCMLQESCLLYGISPHQNILPVLHVCSFGRFDRPIEDHDPPF

VCYRHQG-FGNLKKFLTICRHGDKTKGAQTLRTHQLVSLATQVSSAVAHIHKYRIVHNDIAARNCLIAEVNGRLQVQLCDSALSRDLFPADYHCLGDNEN
|||.|.. .||||.||..||| ||.|..|...|||||..|.|......|.||.||||.|||.|||.|.|.||||||..|||||||||||.||||||||||
VCYPHMNNWGNLKQFLQDCRH-DKPKCHQAISTHQLVHMAIQITMGMMHLHKHRIVHKDIATRNCVIDEQNGRLQVKICDSALSRDLFPMDYHCLGDNEN

RPLKWMSPEAIANELYSSAADVWSLGVLLWELMSLGGSPHAEIDPEEVYTMILKGKRLQQPNNCPDQLYEVMLCCWRVLSEDRPSSEQVVHGL
||.||||.|......||.|.||||.||..||||.||..|..||||.|.|.....|.|||||.||||.|..||.|||....|.||...|.|  |
RPVKWMSLESLQHKHYSHASDVWSFGVTMWELMTLGQMPYMEIDPFEMYHYLKDGYRLQQPFNCPDELFTVMACCWHCMPEERPTFQQLVQCL
Kinase lin-18.AA TK 260-551 15 5e-67 223.47 In-house 1-486 (486) Show / Hide 
Range on Protein: 260-551
Range on HMM: 1-486/486
Sequence Identity: 15% (75 aa)

FQSLPLDMEGTFG---EVRYAIWRQVDDVLNGDVDDE----------EDTFCNQEAVYTKTLKNNASPI-QLD-------------RFLSDALLFYN-IT
 . .    || ||   ||. ..||. ..  . . ...          ..  . . || ........|.  ..|             .... . .. . . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

PHQNLSQVACVASFGRFDRPET---VTDFPLVCYRHQGFGN----LKKFLTICRHGDKT-----------------------------------------
 |.|. .   | . |.  ....   .   ...   .   |.    |...|  ||.. ..                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------KGAQTLRTHQLVS-------------------LATQVSSAVAHIHKY------RIVHNDIAARNCLIAEVNGR--------LQVQLCDSA----
         ..|.|..|..                    . |.... ...|.       ..|| |.||||||..| | .        ... ..|      
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LSRDLFPADYHCLGD------------------------NENRPLKWMSPEAIANEL---------YSSAADVWSLGVLLWELMSLG-GSPHAEID
    |.||. . |. .  .                        .   |..||.||...            .... ||||.|||.||....| . .. ...
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

P---------EEVYTMILKG--------------KRLQQPNNCP--------------DQLYEVMLCCWRVLSEDRPSSEQVVHGL
          .||. .. .|               |. || .||              . .|..|..||.   ||||. .|... |
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase lin-18.AA Pkinase_Tyr 368-551 34 1e-64 219.83 Pfam 92-270 (270) Show / Hide 
Range on Protein: 368-551
Range on HMM: 92-270/270
Sequence Identity: 34% (64 aa)

GNLKKFLTICRHGDKTKGAQTLRTHQLVSLATQVSSAVAHIHKYRIVHNDIAARNCLIAEVNGRLQVQLCDSALSRDLFPADYH-CLGDNENRPLKWMSP
|.|...|   |      . | | ...|.. ..|.... .. .  ...| |.||||||..|    ..|  ||  |.||... ||    ...   | |||.|
GDLLDYLRKHR-----EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAP

EAIANELYSSAADVWSLGVLLWELMSLGGSP-HAEIDPEEVYTMI-LKGKRLQQPNNCPDQLYEVMLCCWRVLSEDRPSSEQVVHGL
|.|..  .... |||| |||.||....|..|  .....|||| .|  .| |. .| |||| .|..|. ||.   ||||. ..... |
ECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase lin-18.AA TK-Unique 368-551 28 8.3e-54 183.91 In-house 90-294 (294) Show / Hide 
Range on Protein: 368-551
Range on HMM: 90-294/294
Sequence Identity: 28% (59 aa)

GNLKKFLTICRHG----------------DKTKGAQT-LRTHQLVSLATQVSSAVAHIHK--YRIVHNDIAARNCLIAEVNGRLQVQLCDSALSRDLF-P
||| ..|  || .                .. |   . .  ..|.. | |. .. .....  ..|||.|..|||.|..|   .... .||  ..||.  .
GNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE---DKVCKICDFGMARDVYTN

ADYHCLGDNENRPLKWMSPEAIA--NELY-SSAADVWSLGVLLWELMSLGGSPHAEIDPEEVYTMILKGKRLQQPNNC-PDQLYEVMLCCWRVLSEDRPS
 .|   .  .  |..||.||..    . | ..  ||||.|||.||...||. |  ....... ..| .|.|..||..| ....|..| .||.   |.|||
GVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPS

SEQVVHGL
 .|..| |
FRQIKHRL
Kinase lin-18.AA TyrKc 265-551 24 5.6e-53 183.23 SMART 1-280 (280) Show / Hide 
Range on Protein: 265-551
Range on HMM: 1-280/280
Sequence Identity: 24% (80 aa)

LDM-----EGTFGEVRYAIWRQVDDVLNGDVDDEEDTFCNQEAVYTKTLKNNASPIQLDRFLSDALLFYNI-TPHQN-LSQVACVASFGRFDRPETVTDF
. .     || ||||. ..|.                    . |  |.||..|    .  |.. | .  ..   |.| .  .... . ||         |
ITLGKKLGEGAFGEVYKGTWK--------------------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--------F

-----PLVCYRHQGFGNLKKFLTICRHGDKTKGAQTLRTHQLVSLATQVSSAVAHIHKYRIVHNDIAARNCLIAEVNGRLQVQLCDSALSRDLFPA----
     ...   .   |.||..|  .|.         | . .|.| ..|...  ...|. ...| |.||||||..| .   .|  .|  ||||.       
MYIEPLMIVMEYMPHGDLKDYLRKHRPK--------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQG

---DYHCL--GDNEN--RPLKWMSPEAIANELYSSAADVWSLGVLLWELMSLGGSPHAE-----IDPEEVYTMILKGKRLQQPNN--------CPDQLYE
   ||     .....   |..||.||.|    .... |||| ||..||....|..|. .     ....||.  . .|.|. || |        ||| .|.
ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ

VMLCCWRVLSEDRPSSEQVVHGL
.|..||.   ||||. ..... .
IMKQCWHEDPEDRPTFSEIHECF
Kinase lin-18.AA UTK 368-551 26 2e-45 153.38 In-house 95-296 (296) Show / Hide 
Range on Protein: 368-551
Range on HMM: 95-296/296
Sequence Identity: 26% (54 aa)

GNLKKFLTICRHGDKTKGAQTLRT-HQLVSLATQVSSAVAHIHKYRIVHNDIAARNCLIAEVN----GRLQVQLCDSA---LSRDLFP--------ADYH
|.| ..|  .||.... ..... | ||... | .........|  ..||.|.||||||... .      ... ..|     .||..           .| 
GDLRSYL--RRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYY

CLGDNENR-PLKWMSPEAIANE-LYSSAADVWSLGVLLWELMSLGGSPHAEIDPEEVYTMILKG--KRLQQPNNCPDQLYEVMLCCWRVLSEDRPSSEQV
.  .. .| |..||.|||...   .... ||||.||..||... |  | ...  ..| . ...|   |. .|  ||...|..|. ||.   ..||. |..
YMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDL

VHGL
|  .
VQQM
Kinase lin-18.AA KIN6 389-551 31 4.8e-43 139.97 In-house 141-305 (305) Show / Hide 
Range on Protein: 389-551
Range on HMM: 141-305/305
Sequence Identity: 31% (53 aa)

LRTHQLVSLATQVSSAVAHIHKYRIVHNDIAARNCLIAEVNGRLQVQLCDSALSR--DLFPADYHCLGDNENR--PLKWMSPEAIANELYSSAADVWSLG
.|  .|.. | |..     .|  ...| |.|||| |. | ..       |  | |  .   . |  .|.   |  |.|||.||...   .|   |||| |
IRHKDLYMFAWQICDGMEYLHSKNCIHRDLAARNVLVTEGCRMKTCKISDFGLCRYPYMDQFQYTSKGG---RYLPIKWMAPECLKHYEFSYKSDVWSFG

VLLWELMSLGGSPHAEID-PEEVYTMILKGKRLQQPNNCPDQLYEVMLCCWRVLSEDRPSSEQVVHGL
||..|. |||..| .|.  |.|.   ...|.|...| .||.. |..|  ||  ...|||   ..   .
VLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKWCPEEIYDIMQSCWQEKPDDRPEFNEMRMQF
Kinase lin-18.AA Musk 385-551 34 1.1e-40 131.97 In-house 119-282 (282) Show / Hide 
Range on Protein: 385-551
Range on HMM: 119-282/282
Sequence Identity: 34% (58 aa)

GAQTLRTHQLVSLATQVSSAVAHIHKYRIVHNDIAARNCLIAEVNGRLQVQLCDSALSRDLFPADYHCLGDNENRPLKWMSPEAIANELYSSAADVWSLG
|   |..  .  .| |.    |     . || |.| ||||| |   .  |   |  |||    .||    .|.  |  || ||.|    .. . |||. |
GPPQLKCYHQLCMAKQIACGMAYLSEMMFVHRDLATRNCLINE---HMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPESIWYNQFTYESDVWAYG

VLLWELMSLGGSPHAEIDPEEVYTMILKGKRLQQPNNCPDQLYEVMLCCWRVLSEDRPSSEQVVHGL
|.|||. | .  |   .  |||   |  | .|  |.||| ..|..|  ||  .  |||.  |. | .
VCLWEIFSYALQPYYGMTHEEVIYYIRQGNILSCPENCPQKVYQLMRRCWQKNPADRPFFCQIHHCI
Kinase lin-18.AA Trk 389-551 31 4.5e-40 133.5 In-house 114-275 (275) Show / Hide 
Range on Protein: 389-551
Range on HMM: 114-275/275
Sequence Identity: 31% (52 aa)

LRTHQLVSLATQVSSAVAHIHKYRIVHNDIAARNCLIAEVNGRLQVQLCDSALSRDLFP-ADYHCLGDNENRPLKWMSPEAIANELYSSAADVWSLGVLL
|   |.   | |. |    .    .|| |.|.||||...   .| |.  | ..|||..   ||  .|     |  || ||.|    ..   ||||.|| .
LTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQ---NLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESIMYRKFTYESDVWSFGVVM

WELMSLGGSPHAEIDPEEVYTMILKGKR-LQQPNNCPDQLYEVMLCCWRVLSEDRPSSEQVVHGL
|| .. |  |       ||   |..|.  |..|  ||  .|..|| ||.   . | .  .. . .
WECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase lin-18.AA CCK4 367-551 35 4.3e-39 129.55 In-house 86-273 (273) Show / Hide 
Range on Protein: 367-551
Range on HMM: 86-273/273
Sequence Identity: 35% (68 aa)

FGNLKKFLTICRHGDKTKGA-----QTLRTHQLVSLATQVSSAVAHIHKYRIVHNDIAARNCLIAEVNGRLQVQLCDSALSRDLFPADYHCLGDNENRPL
.| || || . |  . || .     . | | | . ...||     |. . | .| | |||||||       ||  |  .|..|..   ||    .   |.
WGDLKQFLQATRGKNNTKNKGSSSPPPLTTSQKIAICYQVALGMEHLYNNRFIHRDLAARNCLIS---PQMQVKVCYMGLCKDVYNREYHHH-RQKWIPI

KWMSPEAIANELYSSAADVWSLGVLLWELMSLG-GSPHAEIDPEEVYTMILKGK-RLQQPNNCPDQLYEVMLCCWRVLSEDRPSSEQVVHGL
 ||.||.|    ||   |||  ||. ||. . |   || . | ..|   .  || .. ||  |||.||. |. ||     ||.|  .. | |
RWMPPECIFEDEYSTKSDVWAYGVFMWEVFNQGTKMPHEQQDNDQVMQDMQAGKLMWPQPEDCPDKLYRMMHRCWADNPKDRHSFSEITHHL
Kinase lin-18.AA FGFR 412-551 39 7.4e-39 130.05 In-house 156-293 (293) Show / Hide 
Range on Protein: 412-551
Range on HMM: 156-293/293
Sequence Identity: 39% (55 aa)

RIVHNDIAARNCLIAEVNGRLQVQLCDSALSRDLFPADYHCLGDNENRPLKWMSPEAIANELYSSAADVWSLGVLLWELMSLGGSPHAEID-PEEVYTMI
...| | |||| |. . .       ||  |.||    ||     |   | ||| |||     | .  |||| |||||| | .||.|   |   || |.  
KCIHRDLAARNVLVTDDY---VMKICDFGLARDIHCIDYYRKTTNGRLPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYL

LKGKRLQQPNNCPDQLYEVMLCCWRVLSEDRPSSEQVVHGL
  |.|.  | ||.  .| .|  ||.  ...||.  |.|  |
KEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase lin-18.AA Axl 358-549 32 4.9e-38 132.24 In-house 82-267 (267) Show / Hide 
Range on Protein: 358-549
Range on HMM: 82-267/267
Sequence Identity: 32% (62 aa)

PLVCYRHQGFGNLKKFLTICRHGDKTKGAQTLRTHQLVSLATQVSSAVAHIHKYRIVHNDIAARNCLIAEVNGRLQVQLCDSALSRDLFPADYHCLGDNE
|.|      .| |  ||   | ||. .    | .  ||     . . .  . . . .| |.|||||...|    . |   |  ||. ..  ||   |   
PMVILPFMKHGDLHTFLLYSRLGDQPF---YLPLQMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLRE---DMTVCVADFGLSKKIYSGDYYRQGCIA

NRPLKWMSPEAIANELYSSAADVWSLGVLLWELMSLGGSPHAEIDPEEVYTMILKGKRLQQPNNCPDQLYEVMLCCWRVLSEDRPSSEQVVH
  | ||.  |..| ..| | .|||. || .||.|  |  | . .. .|.|  ...|.||.||..| |.||..|  ||..  .||||  ..  
KMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQPEDCMDELYDLMYQCWEADPKDRPSFSVLRE
Kinase lin-18.AA S_TKc 260-556 15 4.8e-12 -0.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 260-556
Range on HMM: 1-231/231
Sequence Identity: 15% (46 aa)

FQSLPLDMEGTFGEVRYAIWRQVDDVLNGDVDDEEDTFCNQEAVYTKTLKNNASPIQLDRFLSDALLFYNITPHQNLSQVACVASFGRFDRPETVTDFPL
.. | .  .|.||.|. ....                   .. |  | .|        .....   .  .   | |. .   |             |.  
YEILRKIGKGAFGKVYKCRHKK-----------------TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD----------DHLY

VCYRHQGF--GNLKKFLTICRHGDKTKGAQTLRTHQLVSLATQVSSAVAHIHKYRIVHNDIAARNCLIAEVNGRLQVQLCDSALSRDLFPADYHCLGDNE
..  . .   |.|....  .... .    . .   .  ... |. .|....|. .|.| |.   | |. |     .. .||  |.| |    ... |   
MVMEYCDGDLGDLFDYIKKRGRHGLR---FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL----TTFCG---

NRPLKWMSPEAIANELYSS-AADVWSLGVLLWELMSLGGSPHAEIDPEEVYTMILKGKRLQQPNNCPDQLYEVMLCCWRVLSEDRPSSEQVVH----GLR
   . .|.|| .    |.  ..|.||.|..|.|... |  |    ...... .|.           .... . .  |...  |.||.  .. .       
--TPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC

DFNI
.  .
HPWF
Kinase lin-18.AA Pkinase 463-551 18 7.7e-12 42.95 Pfam 177-293 (293) Show / Hide 
Range on Protein: 463-551
Range on HMM: 177-293/293
Sequence Identity: 18% (22 aa)

WMSPEAIA-NELYSSAADVWSLGVLLWELMSLGGSPHAEI------DPEEVYTMILK-GKRLQQPNNCP-------------------DQLYEVMLCCWR
.|.|| |  .. |....|.||.|..|.|... |  |  .       |. ... .|..   . . |. |.                   . . ... .|..
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLC

VLSEDRPSSEQVVHG--L
.  ..||. ||...   .
KDPKKRPTAEQILQHPWF
Kinase lin-18.AA TK-Unique 268-336 23 0.012535 5.03 In-house 9-66 (294) Show / Hide 
Range on Protein: 268-336
Range on HMM: 9-66/294
Sequence Identity: 23% (16 aa)

EGTFGEVRYAIWRQVDDVLNGDVDDEEDTFCNQEAVYTKTLKNNASPIQLDRFLSDALLFYNITPHQNL
|| ||.|  .  ....            ... |  |..|.|| ||.. . . ||. . .. ....|.|.
EGAFGQVWRGEVWGIW-----------KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNI
Kinase lin-18.AA Pkinase 392-418 18 0.060412 7.96 Pfam 108-134 (293) Show / Hide 
Range on Protein: 392-418
Range on HMM: 108-134/293
Sequence Identity: 18% (5 aa)

HQLVSLATQVSSAVAHIHKYRIVHNDI
... . ..|. ......|. .|.| |.
WECKFYMYQILRGLEYCHSMGIIHRDL
Kinase lin-18.AA Pkinase_Tyr 268-336 25 3.05713 1.44 Pfam 9-66 (270) Show / Hide 
Range on Protein: 268-336
Range on HMM: 9-66/270
Sequence Identity: 25% (18 aa)

EGTFGEVRYAIWRQVDDVLNGDVDDEEDTFCNQEAVYTKTLKNNASPIQ--LDRFLSDALLFYNITPHQNL
|| ||||. ..|.              |   ..  |  |.||..|.. |  .. |.. | .  ..  |.|.
EGAFGEVYKGTWKG-------------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNI