Gene M04C9.5 (Nematode worm)

M04C9.5

Species: Nematode worm
Alias: aSWK205, CE12408, M04C9.5
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: I:3.65, WormBase Physical Map location: I: 9367900-9370979,

Classification

Group: CMGC
Family: RCK
Subfamily: MAK

Sequence

Name Sequence Type Origin Length Description Download
M04C9.5.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 281 Kinase domain by global Sugen HMM Fasta, JSON
M04C9.5.AA Protein Genbank 527 None Fasta, JSON

Protein domain

Protein domains of M04C9.5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase M04C9.5.AA MAK 45-325 59 3.2e-239 769.96 In-house 1-352 (352) Show / Hide 
Range on Protein: 45-325
Range on HMM: 1-352/352
Sequence Identity: 59% (211 aa)

YLMTKRLGDGTFGEVMLAKK------------------------------IDTGDRVAIKRMKKKFYSWEEAMSLREVKSLKKLN-HPNIIKLREVIR--
|.|.|.|||||.|.|||||.                              ||||..|||||||||||||||.|.||||||||||| ||||.||.||||  
YQMIKQLGDGTYGCVMLAKRQFPLSNILGKQHDIRGTLMDQPKNGHQNYIIDTGEKVAIKRMKKKFYSWEECMNLREVKSLKKLNAHPNIVKLKEVIRDS

ENDILYFVFEFMQENLYELMKDRDR-YFPESVIRNIIYQVLQGLAFMHKNGFFHRDMKPENIMCNGT-----------------ELVKIADFGLAREIRS
|||.||||||.|.||||..|||||| .|||.|||||.||.|||||||||.||||||||||||||.|.                 ||.|||||||||||||
ENDHLYFVFEYMKENLYQMMKDRDRRHFPEPVIRNIMYQILQGLAFMHKHGFFHRDMKPENIMCMGPTQYFEKEYMNQIGYQDNELIKIADFGLAREIRS

KPPYTDYVSTRWYRAPEILLRSTSYNSPIDMWALGCIMAELYILRPLFPGTSEMDQLFKIISILGTPNKDE----------------WPEGYQLASAMNF
|||||||||||||||||.|||||.|.|||||||.||||||||..||||||.||.||.|||...||||.||.                ||.|||||..|||
KPPYTDYVSTRWYRAPEVLLRSTYYSSPIDMWAVGCIMAELYTFRPLFPGSSEIDQIFKICQVLGTPKKDDDFVNTNHITAPPPGGFWPDGYQLAHMMNF

RFQQVVA---TPMEQVVNTISK-EGMKLMMDMMLWNPEKRPNANQSLRYKYF
||.|.|.   .|........|. ....||.||..|.|.|||.|.|...|.||
RFPQCVPPSIMPLKHLIPNCSQSDAIELMKDMLQWDPNKRPTAQQCCKYPYF
Kinase M04C9.5.AA RCK 45-325 62 3.3e-232 744.57 In-house 1-298 (298) Show / Hide 
Range on Protein: 45-325
Range on HMM: 1-298/298
Sequence Identity: 62% (186 aa)

YLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEEAMSLREVKSLKKLN-HPNIIKLREVIREND--ILYFVFEFMQENLYELMKD---RDRYF
| ..|.|||||.|.||.|....||. ||||.||.|||||||.|.|||.|||.||| |||||||.||||.||  .||||||.|..|||..|||   |..|.
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKYL

PESV--IRNIIYQVLQGLAFMHKNGFFHRDMKPENIMCNG---------TELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEILLRSTSYNSPIDMWAL
||..  |.||.||.|||||.|||.||||||.|||||||.|         ....|||||||.||||||||||||||||||||||.|||.| ||||.|.||.
PENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDIWAV

GCIMAELYILRPLFPGTSEMDQLFKIISILGTPNKDEWPEGYQLASAMNFRFQQVVATPMEQVVNTISKEGMKLMMDMMLWNPEKRPNANQSLRYKYF
||||.|||.|||||||.||.||.|||....|||||..||.||.|||.|||.|.|....|..|... .|.....||..|. |.|.||..|.|.|...||
GCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase M04C9.5.AA CMGC 45-325 24 3.2e-129 427.12 In-house 1-513 (513) Show / Hide 
Range on Protein: 45-325
Range on HMM: 1-513/513
Sequence Identity: 24% (126 aa)

YLMTKRLGDGTFGEVMLAKK--------------IDTGDRVAIKRMKKKFYSWEEA----------MSLREVKSLKKLN-----------------HPNI
|   |..| ||.|.|  ..               ..|. .||||..|..|| ...           ..|||.| ||.||                 |.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

IKLREVIREND-----------------ILYFVFEFMQENLYELMKD--------RDRYFPESV------------IRNII------YQVLQGLA--FMH
.||..... ..                  ||.|||.|. .||...|.        | ....| .            |....      ||.|.||.  ..|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

KNG--FFHRDMKPENIMCNGTELV--------------------KIADFGLAR--EIRSKP--------------------PYTDYVSTRWYRAPEILLR
...  ..|||.|||||. | .  .                    ||.||||||  ...|..                    |||.||.|||||||||||.
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

S---------TSYNSPIDMWALGCIMAELYI--------LRPLFPGTSE-----------MDQLFKIISILGTPN---------------KDEWPE----
.         . |..|||||..|||.||.|         ..||||| ||            ||||||. .||||.               ..|||.    
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

---------------------GYQLASAMNFRFQQVVATPMEQVVNT-----------------------------------ISKEGMKLMMDMMLWNPE
                     .....  .|.||...   | ....                                     .....  |.. |. ..|.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

KRPNANQSLRYKYF
||. | | |.  ||
KRITAEQALQHPYF
Kinase M04C9.5.AA CDK 45-325 35 2.8e-108 347.55 In-house 1-284 (284) Show / Hide 
Range on Protein: 45-325
Range on HMM: 1-284/284
Sequence Identity: 35% (113 aa)

YLMTKRLGDGTFGEVMLAKKIDTG-----DRVAIKRMK---KKFYSWE-EAMS---LREVKSLKKLNHPNIIKLREVIREN-----------DILYFVFE
| . ...| ||.|.|  |.  .||     . ||.|. .   ..  . | | ..   .||.. ||.| ||||.||..|.  .             ||.|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEG-REEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

FMQENLYELMKDRDRYFPESVIRNIIYQVLQGLAFMHKNGFFHRDMKPENIMCNGTEL-----VKIADFGLAREIRS-------KPPYTDYVSTRWYRAP
.|   |...|.          |.....| |.||...|.|.. |||.|| ||. | .       .|||||||||.  .         .||  | |.|||||
YMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAP

EILLRSTSYN--SPIDMWALGCIMAELYI---LRPLFPGTSEMDQLFKIISILGTPNKDEWPEGYQLASAMNFRFQQVVATPMEQVVNTISKEGMKLMMD
|.|| |. |.   |||||..|||.||..     .|||||.|| ||||||. |.|||. | ||.  .|                             |.. 
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNK

MMLWNPEKRPNANQSLRYKYF
|.  .|.|| .| | |  .||
MLCYDPKKRISAEQALQHPYF
Kinase M04C9.5.AA CDK7 45-325 37 7.2e-104 277.52 In-house 1-288 (288) Show / Hide 
Range on Protein: 45-325
Range on HMM: 1-288/288
Sequence Identity: 37% (108 aa)

YLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEEAM------SLREVKSLKKLNHPNIIKLREVIRENDILYFVFEFMQENLYELMKDRDRYF
|   | .| |.|. | .|    ||  ||||. | |  . .||        .||.| |. . |.|.| |. ..   . .. ||.||.  | .  ||    .
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIK-KLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIIL

PESVIRNIIYQVLQGLAFMHKNGFFHRDMKPENIMCNGTELVKIADFGLAREIRS-KPPYTDYVSTRWYRAPEILLRSTSYNSPIDMWALGCIMAELYIL
  . | ..  ..|||| ..|.|   |||.|| |   |    .||||||||| . |    ||  | |||||||| |    .| . .|||. |||.|||   
TPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLR

RPLFPGTSEMDQLFKIISILGTPNKDEWPEGYQLASAMNFRFQQV-VATPMEQVVNTISKEGMKLMMDMMLWNPEKRPNANQSLRYKYF
 | .||.|..||| .| ..||||.  |||.  .... . |. .     ||....    | . . ||  | . || ||  . |.|  .||
VPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase M04C9.5.AA CDC2 45-325 37 6.5e-99 304.65 In-house 1-301 (301) Show / Hide 
Range on Protein: 45-325
Range on HMM: 1-301/301
Sequence Identity: 37% (114 aa)

YLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEE---AMSLREVKSLKKLN-HPNIIKLREVIRENDILYFVFEFMQENLYELMK---DRDRY
|   ...| ||.|.|  .|  .|.. ||.|. . .  . ..     ..||   ||.|. ||||.||..|| .   || |||..  .| ..|.     . .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

FPESVIRNIIYQVLQGLAFMHKNGFFHRDMKPENIMCNGTELVKIADFGLAREIRS-KPPYT--DYVSTRWYRAPEILLRSTSYNSPIDMWALGCIMAEL
.|........|| |||..| | .. .||| || ||  . .  .||||||||| .   . .||    | |.|||||||||..  |. |.|||..|||.||.
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---YILRPLFPGTSEMDQLFKIISILGTPNKDEWPEGYQLA-SAMNF-RFQQVVATPMEQVVNT---------ISKEGMKLMMDMMLWNPEKRPNANQSL
      .|||.| || ||||||  |||||| ..||. .||    . | |...   . .....           . .||. | | |   .|.|| .| . |
FMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKP---QDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEAL

RYKYF
. .||
QHPYF
Kinase M04C9.5.AA S_TKc 45-325 30 1.6e-97 331.19 SMART 1-231 (231) Show / Hide 
Range on Protein: 45-325
Range on HMM: 1-231/231
Sequence Identity: 30% (91 aa)

YLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEEAMSLREVKSLKKLNHPNIIKLREVIRENDILYFVFEFMQE---NLYELMKDRDR-----
| . . .| |.||.|.......|| .||||..|         . .||.. ||| .||||.|| .|... | ||.|.|..     .|....|.| |     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

YFPESVIRNIIYQVLQGLAFMHKNGFFHRDMKPENIMCNGTELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEILLRSTSYNS-PIDMWALGCIMAELY
.||| ..| ..||....|...|..|. ||| |||||...    .||.||||||..      | .. |.||.|||.|    .|.  ..|.|..|||..|..
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

ILRPLFPGTSEMDQLFKIISILGTPNKDEWPEGYQLASAMNFRFQQVVATPMEQVVNTISKEGMKLMMDMMLWNPEKRPNANQSLR-------YKYF
  .|.||   .|...||.|                                        |.|.  ... .. ..||||| | . |.         .|
CGYPPFP---QMQMMFKKIG---------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase M04C9.5.AA Pkinase 45-325 30 8.8e-95 325.98 Pfam 1-293 (293) Show / Hide 
Range on Protein: 45-325
Range on HMM: 1-293/293
Sequence Identity: 30% (93 aa)

YLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEEAMSLR---EVKSLKKLNHPNIIKLREVIRENDILYFVFEFMQE-----NLYELMK-DRD
|   ...| |.||.| ......||..||.|..||.  .... ...|   |.. .|.||||||..|... ...| .|.|.|...       |..... .|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RYF--PESVIRNIIYQVLQGLAFMHKNGFFHRDMKPENIMCNGTELV----KIADFGLARE--IRSKPPYTDYVSTRWYRAPEILLRSTSYNSPIDMWAL
. |  .| ......||.|.||...|..|. |||.|||||... .  .    ||.|||||.   . ... .|... |.||.|||... .. | ...|||..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCIMAELYILRPLFPGT----SEMDQLFKIISILGTPNKDEWPEGYQLASAMNFRFQQVVATPMEQVVNTISKEGMKLMMDMMLWNPEKRPNANQSLRYK
|||..|..  ||.|||     . .||...|  |.|.|.. .||. .     . ||. .   .  . .   .|.|. ... ..  ..|.|||.| | |  .
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

YF
.|
WF
Kinase M04C9.5.AA MOK 45-325 40 2.2e-90 283.48 In-house 1-283 (283) Show / Hide 
Range on Protein: 45-325
Range on HMM: 1-283/283
Sequence Identity: 40% (114 aa)

YLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEEAMSLREVKSLKKLN-HPNIIKLREVI--RENDILYFVFEFMQENLYELMKDRDRYFPES
|    ..|.||| |||  . .  |.  | |.||..| | |.  .|||.. ...|| ||||..|.||.  |    |  . | |  |.|||.. |  | |. 
YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNNLREIQAMRRLNPHPNILMLHEVVFDRKTGNLALICELMDMNIYELIRGRRHYLPQK

VIRNIIYQVLQGLAFMHKNGFFHRDMKPENIMCNGTELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEILLRSTSYNSPIDMWALGCIMAELYILRPLF
 |.. .||... |  ||.|| ||||.|||||.    . .|.||||  | . || |||.|.||||||||| ||    |   .|||. ||.  |.  |.|||
KIMHYMYQLCKSLDHMHRNGIFHRDVKPENILIK-QDHLKLADFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGYYTYQMDMWSVGCVFYEIASLHPLF

PGTSEMDQLFKIISILGTPNKDEWPEGYQLASAMNFRFQQVVATPMEQVVNTISKEGMKLMMDMMLWNPEKRPNANQSLRYKYF
||  |.||. ||  ..||| .       . . |||. |       .|...  ..|  ...|  |. . |. |  | | ..  ||
PGVNEVDQISKIHDVMGTPCQKILNKFKNQSRAMNYDFPFKKGSGIEKLTPNLTKQCLEIMHKMCTYDPDERITAHQVIQHPYF
Kinase M04C9.5.AA CDK5 45-325 36 7.4e-81 255.14 In-house 1-287 (287) Show / Hide 
Range on Protein: 45-325
Range on HMM: 1-287/287
Sequence Identity: 36% (108 aa)

YLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEE---AMSLREVKSLKKLNHPNIIKLREVIRENDILYFVFEFMQENLYELMKDRDRYFPES
|    ..|.||.| |  |.  .|.  ||.||   .  |  |   .  .||.  || | |.||. |  ||  .  |  ||||. . |   | ..  .    
YEKMEKIGEGTYGTVYKARNKETHEIVALKRV--RLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMH

VIRNIIYQVLQGLAFMHKNGFFHRDMKPENIMCNGTELVKIADFGLARE----IRSKPPYTDYVSTRWYRAPEILLRSTSYNSPIDMWALGCIMAELY-I
.|. ..|| |.|||| |..   |||.|| | . |     | |||||||     .|    |.  | | |||.| .|. |  |. .||||  |||.||.   
IIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRC---YSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANA

LRPLFPGTSEMDQLFKIISILGTPNKDEWPEGYQLASAM--NFRFQQVVATP-MEQVVNTISKEGMKLMMDMMLWNPEKRPNANQSLRYKYF
.||||||... |||..|  |.|||. |.||   .|         .    |.. ..|.|   ...|| |.  |.  ||..|  |.. |.  ||
GRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase M04C9.5.AA MAPK 45-263 34 1.3e-76 260.88 In-house 1-257 (328) Show / Hide 
Range on Protein: 45-263
Range on HMM: 1-257/328
Sequence Identity: 34% (88 aa)

YLMTKRLGDGTFGEVMLAKKID------TGDRVAIKRMKKKFYSWEEAM-SLREVKSLKKL-NHPNIIKLREVIRE------NDI-----LYFVFEFMQE
|   |..| | .| |  |.         .|..||||.. . | .   .   .||.| |. . .|.|||||.....       |..     .|.|.|.|. 
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

NLYELMKDRDRYFPESVIRNIIYQVLQG--LAFMHKNGFFHRDMKPENIMCNGTELVKIADFGLAREIRSKPPY---------------TDYVSTRWYRA
.|. ..| ..    .  |. ..||.| |  | ..|  .  ||| ||.|| .|   ..||.|||||| | ..  .               |.||.||||||
DLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRA

PEILLR--STSYNSPIDMWALGCIMAELYI-LRPLFPGTSEMDQLFKIISILGTPNKD
|||.|   .. |.  .|||..|||.||..   .|||||.. .||...|...|||| ..
PEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEE
Kinase M04C9.5.AA CDKL 45-259 41 1.4e-74 254.09 In-house 1-218 (286) Show / Hide 
Range on Protein: 45-259
Range on HMM: 1-218/286
Sequence Identity: 41% (91 aa)

YLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMKK-KFYSWEEAMSLREVKSLKKLNHPNIIKLREVIRENDILYFVFEFMQENLYELMKDRDRYFPESVI
|    ..| |  | ||  .  .||  ||||. |  .    .    .||.| || | |.||  |.|| | .  |. |||..  .. .. . . .  .|.|.
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLKHENIVNLIEVFRRKRKLHLVFEYCDHTVLHELEEYPNGVDEHVV

RNIIYQVLQGLAFMHKNGFFHRDMKPENIMCN-GTELVKIADFGLAREIRSKPP--YTDYVSTRWYRAPEILLRSTSYNSPIDMWALGCIMAELYILRPL
|....|.|....| ||.   ||| |||||  .     ||. |||.|| . .||   ||||| |||||||| |.  |.| .|.|.||.||.|||.    ||
RKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFAR-MLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQPL

FPGTSEMDQLFKIISILGT
.|| |. |||..|.  ||.
WPGQSDIDQLYHIQKCLGP
Kinase M04C9.5.AA Pkinase_Tyr 45-205 26 1.9e-19 66.48 Pfam 1-176 (270) Show / Hide 
Range on Protein: 45-205
Range on HMM: 1-176/270
Sequence Identity: 26% (47 aa)

YLMTKRLGDGTFGEVMLAKKI----DTGDRVAIKRMKKKFYSWEE---AMSLREVKSLKKL-NHPNIIKLREVIR-ENDI--LYFVFEFMQE-NLYELMK
  . | || | ||||....      .|.  ||.| . |  .. |.   .. .||.| .|.| .||||..|  |.  . .   .| |.|.|.  .|..  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

DR---DRYFPESVIRNIIYQVLQGLAFMHKNGFFHRDMKPENIMCNGTELVKIADFGLAREIRSKPPY-TDYVSTRW
..   .. .. . . .. .|. .|... . ... |||    |.. . .  |||.|||||| | ..  | .   ....
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKL
Kinase M04C9.5.AA TyrKc 45-325 21 6.5e-15 18.47 SMART 1-280 (280) Show / Hide 
Range on Protein: 45-325
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

YLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEEAMSLREVKSLKKL--NHPNIIKLREVIREN-------DILYFVFEFMQE-NLYELMKDR
  . | || | ||||.... .     ||.| .|.      ... .|| . ..||  .||||..|  |...        . |. |.|.|   .| .  ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

DRYFPESVIRNIIYQVLQGLAFMHKNGFFHRDMKPENIMCNGTELVKIADFGLAREIRSK-------PPYT------DY--VSTRWYRAPEILLRSTSYN
 . .. .   .. .|. .| .. |.... |||    |.. .    |||.||||.|.| ..         |.          .  ||. ||| . .   ..
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NYGKFT

SPIDMWALGCIMAELYIL-RPLFPG---TSEMDQLFKIISILGTPNKDEWPEG----YQLASAMNFRFQQVVATPMEQVVNTISKEGMKLMMDMMLWNPE
.  | |. |  | |.. .  .  ||      |   . .|  . . .  . |.                             . ..|  ..| .    .||
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------F-VCCPDEMYQIMKQCWHEDPE

KRPNANQSLRYKYF
.||. ..   ...|
DRPTFSEI--HECF
Kinase M04C9.5.AA CDKL 286-325 24 4.5e-05 13.28 In-house 246-286 (286) Show / Hide 
Range on Protein: 286-325
Range on HMM: 246-286/286
Sequence Identity: 24% (10 aa)

PMEQVVNTIS-KEGMKLMMDMMLWNPEKRPNANQSLRYKYF
| |. . ..| |. . .|  ..  .| .|... |...  ||
PLEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF