Gene mbk-1 (Nematode worm)

mbk-1

Species: Nematode worm
Alias: aSWK179, CE06352, T04C10.1, mbk-1
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: X: 14828650-14823638, WormBase Genetic Map location: n/a,

Classification

Group: CMGC
Family: DYRK
Subfamily: DYRK1

Sequence

Name Sequence Type Origin Length Description Download
mbk-1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 322 Kinase domain by global Sugen HMM Fasta, JSON
mbk-1.AA Protein Genbank 948 None Fasta, JSON

Protein domain

Protein domains of mbk-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase mbk-1.AA DYRK1 394-715 75 2.6e-234 784.68 In-house 1-321 (321) Show / Hide 
Range on Protein: 394-715
Range on HMM: 1-321/321
Sequence Identity: 75% (243 aa)

ILSDTPVGKGSFGQVTKAYDTLNKEEVAIKIIKNKKTFFDQAQIEIHLLELTNAHDKDNKYNIVTLKGHFVHRAHLCLVFELLSYNLYDLLKNTSFRGVS
...|...||||||||.||||....|.||||||||||.|..||||||.||||.|.|||..||.||.||.||..|.|||||||||||||||||.||.|||||
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVS

LNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRSQIRVIDFGSSCQTGHRIYQYIQSRFYRSPEVLLGIAYDTKIDMWSLGCILVEMHTGE
|||.||||||....|||.|.|||.||||||||||.||.|.|||.|..||||||||.|.||||||||||||||||||||.||..|||||||||||||||||
LNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGE

PLFAGSSEVDQMMKIVEVLGMPPKEMLDIGPKTHKYFDKTEDGIYYCKKTRDGYRHTYKAPGARKLHEILGVTSGGPGGRRLGEPGHSVEDYSKFKDLIK
|||.||.|||||.|||||||||||.|.|..||.||||.|..|...|||||||...| ||.|..|||||||||..|||||||.||||||||||.|||||||
PLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYFEKDPDNTWYCKKTRDKKKH-YKEPCTRKLHEILGVETGGPGGRRKGEPGHSVEDYLKFKDLIK

RMLQFDPKQRISPYYVVRHPFL
||||.||||||.|||...|.|.
RMLQYDPKQRITPYYALQHSFF
Kinase mbk-1.AA DYRK 394-715 50 8e-187 626.95 In-house 1-320 (320) Show / Hide 
Range on Protein: 394-715
Range on HMM: 1-320/320
Sequence Identity: 50% (166 aa)

ILSDTPVGKGSFGQVTKAYDTLNKEEVAIKIIKNKKTFFDQAQIEIHLLELTNAHDKDNKYNIVTLKGHFVHRAHLCLVFELLSYNLYDLLKNTSFRGV-
   . . |||||||| |..|. ..| ||||||.|.| |..||||||..||. | .|.|.||..| .. .|.|| |||.||||||.|||..|||..|.|. 
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFF

SLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNA-KRSQIRVIDFGSSCQTGHRIYQYIQSRFYRSPEVLLGIAYDTKIDMWSLGCILVEMHT
|||| ||||||. . |.||...| .||||||||||..|... ..|.| ||||||||. ..|||.||||||||.|||.||. |...||||||||||.|..|
SLNLVRKFAQQILTCLKFLHKNE-NIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFT

GEPLFAGSSEVDQMMKIVEVLGMPPKEMLDIG--PKTHKYFDKTEDGIYYCKKTRDGYRHTYKAPGARKLHEILGVTSGGPGGRRLGEPGHSVEDYSKFK
|.|||.|..|.||. .|.||||||||.|.| |  ...||.||.     |........ ........ .|.|.... ....|.||| ..|.|   |...||
GWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC---FMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQ-CDDHQFK

DLIKRMLQFDPKQRISPYYVVRHPFL
|.||..||.||..||.|..  .||..
DFIKKCLQWDPHKRITPSQALQHPWF
Kinase mbk-1.AA DYRK2 392-715 42 2.1e-120 393.37 In-house 1-318 (318) Show / Hide 
Range on Protein: 392-715
Range on HMM: 1-318/318
Sequence Identity: 42% (145 aa)

YVILSDTPVGKGSFGQVTKAYDTLNKEEVAIKIIKNKKTFFDQAQIEIHLLELTNAHDKDNKYNIVTLKGHFVHRAHLCLVFELLSYNLYDLLKNTSFRG
| ||.    |||||||| |.||  .|. ||||.| ||| |  ||..||  |.    .|||| .|.| ..  |. | |.|..||||| |||...|. .| |
YEILE--VIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQG

VSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRSQIRVIDFGSSCQTGH-RIYQYIQSRFYRSPEVLLGIAYDTKIDMWSLGCILVEMH
 ||.| |.||... . | ||.  .  ||||||||||.||  . || | ||||||||     ||| ||||||||.||| ||. |.. |||||.|||..|. 
FSLQLVRRFAHSILQCLRFLH--KNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELY

TGEPLFAGSSEVDQMMKIVEVLGMPPKEMLDIG-----PKTHKYFD---------KTEDGIYYCKKTRDGYRHTYKAPGARKLHEILGVTSGGPGGRRLG
|| |||.|. |.||.  . ||||||||...|        ..  .|.            |.  . .| .   .   . ||.... ..|  .          
TGYPLFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCFRRKYFFNSHCFEWYCTFMTDHSMEIPKHYKNRHGKRRPPGSKSWKSVLKGC----------

EPGHSVEDYSKFKDLIKRMLQFDPKQRISPYYVVRHPFL
      ||.. | | ||| .. ||..|..|    .||..
------EDEN-FIDFIKRCFEWDPSERMTPSQALKHPWI
Kinase mbk-1.AA CMGC 394-715 21 1.4e-109 361.44 In-house 1-513 (513) Show / Hide 
Range on Protein: 394-715
Range on HMM: 1-513/513
Sequence Identity: 21% (111 aa)

ILSDTPVGKGSFGQVTKAYDTL--------------NKEEVAIKIIKNKKTFFDQAQ-------------IEIHLLELTN-AHDKDN-----------KY
   . ..|.|..|.| |..|..              ..|.||||.|||.. . .||.              || .|.  | .||. |           . 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN

NIVTLKGHFVHRA-----------------HLCLVFELLSYNLYDLLKNTS--------------------------FRGVSLNLARKFAQQLGKTLL--
|||.|. .|.|.                  ||.||||.. ..||...||..                           .  .. . | ...|. . |   
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

FLSSPELSIIHCDLKPENVLLVNAKRS------------------QIRVIDFGSSCQTGHR------------------------IYQYIQSRFYRSPEV
.. |  ..|||.||||||.|. . ...                  .....|||........                        ...|...|.||.||.
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI

LLGIA----------YDTKIDMWSLGCILVEMHTG--------EPLFAGSSE-----------VDQMMKIVEVLGMPPKEMLDIG-------PKTHKYFD
|||            |.|.|||||.|||. || ||        .||| |.||           .||. ||..|||.|. .|.. |       ... ....
LLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPN

KTEDGIY--------YCKKTRDGYRHTYKAPGARKLHEILGVTSGGPGGRRLGEPGHSV-------------------------------EDYSKFKDLI
...   |        .  .   .......  . ....  .      |   .  .|.|.                                 . ... ||.
MIKLPWYNKFPKKWNW--Q---TMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLL

KRMLQFDPKQRISPYYVVRHPFL
|.|||.||..||..    .||..
KKMLQYDPDKRITAEQALQHPYF
Kinase mbk-1.AA YAK 392-630 45 1e-100 340.93 In-house 1-239 (347) Show / Hide 
Range on Protein: 392-630
Range on HMM: 1-239/347
Sequence Identity: 45% (111 aa)

YVILSDTPVGKGSFGQVTKAYDTLNKEEVAIKIIKNKKTFFDQAQIEIHLLELTNA-HDKDNKY---NIVTLKGHFVHRAHLCLVFELLSYNLYDLLKNT
|..| |   |.| |||| |    . .| .|.|.|||.  .| ||  || .|.. |  || .||     |. .   |||. |.|||||.|| |||..||..
YIVL-DM-LGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQN

SFRGVSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRSQIRVIDFGSSCQTGHRIYQYIQSRFYRSPEVLLGIAYDTKIDMWSLGCILV
 |.| | .| | .  |    .  | .    ||||||||||..| .  .  |..||||||||.   .| |||.|.|||||..... | | |||||||||..
KFCGFSFQLIRQWTKQILDGMCVLENKQ--IIHCDLKPENIMLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVA

EMHTGEPLFAGSSEVDQMMKIVEVLGMPPKEMLDIGPKTHKYF
|   | |.| | || .|.  |...|| || .|.| |    |||
ELFLGLPIFPGNSEYNQIKRIIDMLGYPPSWMIDQGRFKNKYF
Kinase mbk-1.AA S_TKc 394-715 24 6.2e-76 259.5 SMART 1-231 (231) Show / Hide 
Range on Protein: 394-715
Range on HMM: 1-231/231
Sequence Identity: 24% (82 aa)

ILSDTPVGKGSFGQVTKAYDTLNKEEVAIKIIKNKKTFFDQAQIEIHLLELTNAHDKDNKYNIVTLKGHFVHRAHLCLVFELLSY---NLYDLLKNTSFR
     ..|||.||.| |....  ...|||||||      .... || .|.        .  |||.|...|..  ||..|.|...    .|.|..|.   .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

G----VSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRSQIRVIDFGSSCQTGHRIYQYIQSRFYRSPEVLLGIAYDT-KIDMWSLGCI
|     .   ||....|. . | .. |  . |||.||||||.|| .    .| ..|||...|     . .. ...|..||||    |.. |.|.||.|||
GLRFPFPE-HARFYMYQICCALEYCHS--HGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

LVEMHTGEPLFAGSSEVDQMMKIVEVLGMPPKEMLDIGPKTHKYFDKTEDGIYYCKKTRDGYRHTYKAPGARKLHEILGVTSGGPGGRRLGEPGHSVEDY
| || .|.|.|    ....|.|..                                                                            
LYEMLCGYPPFP---QMQMMFKKIG--------------------------------------------------------------------------S

SKFKDLIKRMLQFDPKQRISPYYVVR-------HPFL
. .||.|...||.||..|..   . .       ||..
PEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase mbk-1.AA HIPK 392-635 39 8.7e-68 212.4 In-house 1-242 (329) Show / Hide 
Range on Protein: 392-635
Range on HMM: 1-242/329
Sequence Identity: 39% (97 aa)

YVILSDTPVGKGSFGQVTKAYDTLNKEEVAIKIIKNKKTFFDQAQIEIHLLELTNAHDKDNKYNIVTLKGHFVHRAHLCLVFELLSYNLYDLLKNTSFRG
| .|     |.| |||| |.     .| |||||.||   .  | |||. .|.     . |. |..|     | |. | |||||.|  |||| .|.  |  
YEVLE--FLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADE-YHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMP

VSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRS--QIRVIDFGSSCQTGHRIYQ-YIQSRFYRSPEVLLGIAYDTKIDMWSLGCILVE
  |.  |   ||  . |. |   ||..|| ||||||..||  .|    ..||||||     . . . |.|||.|| ||..||. .  ..|||||||.. |
LPLKHIRPILQQVLTALMKLK--ELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAE

MHTGEPLFAGSSEVDQMMKIVEVLGMPPKEMLDIGPKTHKYFDKTED
 . | ||. |..| ||   | .  . | . .|  . |.|..||. ..
LFLGWPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFDRDKQ
Kinase mbk-1.AA Pkinase 394-715 24 6.4e-60 210.18 Pfam 1-293 (293) Show / Hide 
Range on Protein: 394-715
Range on HMM: 1-293/293
Sequence Identity: 24% (87 aa)

ILSDTPVGKGSFGQVTKAYDTLNKEEVAIKIIKNKKTFFDQAQI-----EIHLLELTNAHDKDNKYNIVTLKGHFVHRAHLCLVFELLSY-----NLYDL
.    ..|.||||.| |...  . ..||.|||| ...  .. |.     ||...   | |.      ||.|.. |  . |...|.|..        |.|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPN-----IVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY

LK---NTSFRGVSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRSQI----RVIDFGSSCQ---TGHRIYQYIQSRFYRSPEVLL-GIA
..   ...|   | . ..... |. . | .. |   .|||.||||||.|..  .. .|    ...|||...|    ..  . .  ...|..|||.. |  
ISTWRHGCFY-FSEWECKFYMYQILRGLEYCHS--MGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQY

YDTKIDMWSLGCILVEMHTGEPLFAGS----SEVDQMMKIVEVLGMPPKEMLDIGPKTHKYFDKTEDGIYYCKKTRDGYRHTYKAPGARKLHEILGVTSG
|..|.||||.|||| || .|.|.| |.    . .||| .|....| |...  .       .|... .                                 
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-H-------------------------------

GPGGRRLGEPGHSVEDY---SKFKDLIKRMLQFDPKQRISPYYVVRHPFL
         . |..  .   . .||.||..|..|||.|...  .. ||..
---------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase mbk-1.AA PRP4 392-632 36 5.6e-52 178.99 In-house 1-241 (320) Show / Hide 
Range on Protein: 392-632
Range on HMM: 1-241/320
Sequence Identity: 36% (90 aa)

YVILSDTPVGKGSFGQVTKAYDTLNKE-EVAIKIIKNKKTFFDQAQIEIHLLELTNAH--DKDNKYNIVTLKGHFVHRAHLCLVFELLSYNLYDLLKN-T
| . .  ..|.| |. | .. |. .   .|||||| |.    .    |.  |   |    ||. |. .| .. || || |.||||| .| || ..||   
YRVYG--YCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKYG

SFRGVSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRSQIRVIDFGSSCQ-TGHRIYQYIQSRFYRSPEVLLGIAYDTKIDMWSLGCIL
   | .|.  | .||||   |  |    . |.| |.|| | .|||  .. .  .||||  .     |  | .|||||.||...|. ||  ||||| || |
KDVGLHLKAVRSYAQQLFLALKHLK--KCNILHADIKPDN-ILVNESKNTLKMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTL

VEMHTGEPLFAGSSEVDQMMK-IVEVLGMPPKEMLDIGPKTHKYFDK
 |. ||  .| |..   .|.| . .. |  |. |.  |    ..||.
YELYTGKIMFPGKTN-NHMLKLFMDYKGKMPNKMIRKGQFKDNHFDQ
Kinase mbk-1.AA DyrkP 392-596 39 7e-50 162.11 In-house 1-205 (323) Show / Hide 
Range on Protein: 392-596
Range on HMM: 1-205/323
Sequence Identity: 39% (83 aa)

YVILSDTPVGKGSFGQVTKAYDTLNKEEVAIKIIKNKKTFFDQAQIEIHLLELTNAHDKDNKYNIVTLKGHFVHRAHLCLVFELLSYNLYDLLK----NT
| |.    .|   | .  .  |      . .||| | | .|||.  || ||   |        |..     | |. || .. |||  |||.  |    | 
YQIMEY--LGSAAFSKAIQCQDKQTNQMMCMKIIENNKDYFDQSIDEIKLLRYINYNGDVDEKNVLRYYDYFYHKEHLFIITELLKDNLYEFYKFNRENE

SFRGVSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRSQIRVIDFGSSCQTGHRIYQYIQSRFYRSPEVLLGIAYDTKIDMWSLGCILV
  |   .    |  ||.  .| .. |  | .|||||||||.|.    . |...|||||||     .  |.||| || |||..|  || .|||||||||| 
QQRYFTVGRLQKITQQILIALDYIHS--LRLIHCDLKPENILMKSYPKCQVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILA

EMHTGEPLF
|. ||  ||
ELWTGNVLF
Kinase mbk-1.AA CDK 392-715 25 6.3e-48 151.34 In-house 1-284 (284) Show / Hide 
Range on Protein: 392-715
Range on HMM: 1-284/284
Sequence Identity: 25% (94 aa)

YVILSDTPVGKGSFGQVTKAYDTLNK-----EEVAIKIIK---N----KKTFFDQ-AQIEIHLLELTNAHDKDNKYNIVTLKGHFVHR-----------A
| .|    .| |..|.| || |....     . ||.| |.   .    .|. | . |  || ||     |.     |||.|.  ...             
YEKLE--KIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HP-----NIVKLHDVCHTKNMDRNNKDKHEN

HLCLVFELLSYNLYDLLKNTSFRGVSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRS----QIRVIDFGSSCQTG--------HRIYQ
 | .||| . . |. ...            . . .|| . | .. |    |.| |||| | .|.| . .    .. . ||| ..  |         | | 
KLYMVFEYMDHDLKKYMD-----------IKCYMWQLLRGLHYCHS--NWIMHRDLKPQN-ILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYT

-YIQSRFYRSPEVLL-GIAYD--TKIDMWSLGCILVEMHT---GEPLFAGSSEVDQMMKIVEVLGMPPKEMLDIGPKTHKYFDKTEDGIYYCKKTRDGYR
  .  . ||.||.||    |.  | |||||.|||..|| |   ..||| |.|| ||. || ...| |  ..     |   |                   
HEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------

HTYKAPGARKLHEILGVTSGGPGGRRLGEPGHSVEDYSKFKDLIKRMLQFDPKQRISPYYVVRHPFL
                                         ||. .||..|||.|||      ||..
-----------------------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase mbk-1.AA CLK 392-532 31 1.8e-37 109.39 In-house 1-149 (350) Show / Hide 
Range on Protein: 392-532
Range on HMM: 1-149/350
Sequence Identity: 31% (48 aa)

YVILSDTPVGKGSFGQVTKAYDTLN-KEEVAIKIIKNKKTFFDQAQIEIH--LLELTNAHDKDNKYN--IVTLKGHFVH-RAHLCLVFELLSYNLYDLLK
|.|..   .| | || | .  |. | |  ||.|||.| . . ..|..||   .  ....||..|||   .. .   | .  .| |.||||.  ..||..|
YEIVCT--LGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMK

NTS------FRGVSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVN
 ..      ...  ..  |..| || . . || .  ....| |||||| ..|.
SNNSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHD--MKLTHTDLKPENICFVD
Kinase mbk-1.AA CLK 538-615 37 9.4e-20 55.24 In-house 186-266 (350) Show / Hide 
Range on Protein: 538-615
Range on HMM: 186-266/350
Sequence Identity: 37% (30 aa)

IRVIDFGSSC---QTGHRIYQYIQSRFYRSPEVLLGIAYDTKIDMWSLGCILVEMHTGEPLFAGSSEVDQMMKIVEVLGMP
|.||||||     .     .  ...| || ||| ||  . .. | || ||||.|  ||. || . .... .  . ...|||
ICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMP
Kinase mbk-1.AA TyrKc 394-715 16 4.5e-10 -59.74 SMART 1-280 (280) Show / Hide 
Range on Protein: 394-715
Range on HMM: 1-280/280
Sequence Identity: 16% (58 aa)

ILSDTPVGKGSFGQVTKAYDTLNKEEVAIKIIKNKKTFFDQAQI--EIHLLELT--NAHDKDNKYNIVTLKGHFVHR-------AHLCLVFELLSY-NLY
|  .   | | ||.| |.  .   ..||.| .|. .    .. .  |. ..     .        ||| | |  ..          |..|.|. .. .| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHP------NIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

DLLKNTSFRGVSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRSQIRVIDFGSSCQTGHR-------IYQYI----QSR-----FYRSP
| |...  . ...    .|. |  .   .|.|    .|| ||   |.|. . .  .... ||| |   ..         |       ...        .|
DYLRKHRPK-LCMKDLLSFCWQIACGMEYLHS--KNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

EVLLGIAYDTKIDMWSLGCILVEMHTGEPLFAGS-----SEVDQMMKIVEVLGMPPKEMLDIGPKTHKYFDKTEDGIYYCKKTRDGYRHTYKAPGARKLH
|..    . || | || |  . |. |              . ..... |.  ...|.   |  |                                    
ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MS---------------------------------

EILGVTSGGPGGRRLGEPGHSVEDYSKFKDLIKRMLQFDPKQRISPYYVVRHPFL
                    .|.  ..  ...|.  ..||..| .   .  | ..
--------------------FVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase mbk-1.AA PRP4 686-715 43 8.4e-10 32.14 In-house 291-320 (320) Show / Hide 
Range on Protein: 686-715
Range on HMM: 291-320/320
Sequence Identity: 43% (13 aa)

SKFKDLIKRMLQFDPKQRISPYYVVRHPFL
. ||||. ..|. ||| ||..  . .|||.
HQFKDLLDKCLMLDPKKRITCNEALKHPFI
Kinase mbk-1.AA HIPK 684-715 34 5.5e-08 20.73 In-house 298-329 (329) Show / Hide 
Range on Protein: 684-715
Range on HMM: 298-329/329
Sequence Identity: 34% (11 aa)

DYSKFKDLIKRMLQFDPKQRISPYYVVRHPFL
|.  | .. |.|.  |...||.|    .||| 
DRREFVHVLKKMCTWDAHKRITPCEALNHPFV
Kinase mbk-1.AA CLK 690-715 46 1.2e-07 18.24 In-house 325-350 (350) Show / Hide 
Range on Protein: 690-715
Range on HMM: 325-350/350
Sequence Identity: 46% (12 aa)

DLIKRMLQFDPKQRISPYYVVRHPFL
|||..|| .|| .||.   .  ||| 
DLIRKMLEYDPSKRITCKDALQHPFF
Kinase mbk-1.AA YAK 688-715 39 8e-06 15.32 In-house 320-347 (347) Show / Hide 
Range on Protein: 688-715
Range on HMM: 320-347/347
Sequence Identity: 39% (11 aa)

FKDLIKRMLQFDPKQRISPYYVVRHPFL
| |.|  .|| .|. | .|     |||.
FIDFINQLLQLNPRERWKPMQAMQHPFI
Kinase mbk-1.AA DyrkP 688-715 28 0.02353 2.79 In-house 296-323 (323) Show / Hide 
Range on Protein: 688-715
Range on HMM: 296-323/323
Sequence Identity: 28% (8 aa)

FKDLIKRMLQFDPKQRISPYYVVRHPFL
| | ....|| |   | .    ..||..
FIDFVRQCLQIDFTRRPTAKEALQHPWF