Gene nsy-1 (Nematode worm)

nsy-1

Species: Nematode worm
Alias: F59A6.1, aSWK301, nsy-1, CE27177
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: II: 5022743-5029907, WormBase Genetic Map location: II:-2.5,

Classification

Group: STE
Family: STE11
Subfamily: ASK

Sequence

Name Sequence Type Origin Length Description Download
nsy-1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 262 Kinase domain by global Sugen HMM Fasta, JSON
nsy-1.AA Protein Genbank 1378 None Fasta, JSON

Protein domain

Protein domains of nsy-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ASK_nterm_v5 nsy-1.AA ASK_nterm_v5 102-156 54 4.1e-33 116.32 In-house 1-55 (55) Show / Hide 
Range on Protein: 102-156
Range on HMM: 1-55/55
Sequence Identity: 54% (30 aa)

DFDKLDFGETETLDLFYNADVALVDVTVTHQQPSLCYHIGVRESMGQSYNMILTY
.|..||||||...|.||||||..||....||||.|.||.|||.|... .|.||..
EFMRLDFGETDMFDEFYNADVVIVDMSIDHQQPNLFYHLGVRHSFKMRNNIILYC
TPR_ASK_1 nsy-1.AA TPR_ASK_1 276-310 52 5.2e-19 62.65 In-house 1-38 (38) Show / Hide 
Range on Protein: 276-310
Range on HMM: 1-38/38
Sequence Identity: 52% (20 aa)

PDTVSLMMLSYRDNQNYGGMIRLVDDLK---RIPDCLK
.|.|. .|.||||.|.|..||.||.|||   .||.|.|
GDIVHNFMHSYRDIQDYDSMIELVEDLKEGEHIPNCCK
TPR_ASK_2 nsy-1.AA TPR_ASK_2 360-402 52 2.2e-30 96.11 In-house 1-46 (46) Show / Hide 
Range on Protein: 360-402
Range on HMM: 1-46/46
Sequence Identity: 52% (24 aa)

PDVVCLAGRIYKDKFIASNYED---RESLNSAIEWYRRAFEMSPLE
||..|..||||||.|..|.|.|   |||...||.|||..||..| .
PDMWCMCGRIYKDMFLESQYTDEAARESRDQAIHWYRKGFEIQPNH
TPR_ASK_3 nsy-1.AA TPR_ASK_3 448-481 58 4.4e-19 69.71 In-house 1-34 (34) Show / Hide 
Range on Protein: 448-481
Range on HMM: 1-34/34
Sequence Identity: 58% (20 aa)

YWDVATYFEVSVLAENYQKACEAALMMVKLKPPV
||||||.||.|.||..|.|...|. .|.|||||.
YWDVATFFEISILACDYHKCMQACECMFKLKPPN
Kinase nsy-1.AA ASK 669-925 72 4.8e-185 620.67 In-house 1-254 (254) Show / Hide 
Range on Protein: 669-925
Range on HMM: 1-254/254
Sequence Identity: 72% (189 aa)

VLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPMN--ENA
||||||||.|||.|||.||..|..|||.......||||.|||.||..|.|.||||||||     ...|..|.||||.|||||||.|||||||||.  ||.
VLGKGTYGIVYAGRDMHTQVRIAIKEIPERDSRYVQPLHEEIALHKQLRHRNIVQYLGC-----CSENGYFKIFMEQVPGGSLSALLRSKWGPMKDNENT

MNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVIDHGQRGYGAPADIWSFGCTMVEMATGRP
||.|.|||||||||||| .|||||||||||||||||||.|||||||||||||.||.|||||||||||||||||.||||||.|||||||||||||||||.|
MNFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTCKRLAGINPCTETFTGTLQYMAPEVIDQGQRGYGKPADIWSFGCTMVEMATGKP

PFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFI
||.|...||||||.|||.|.||.||.|....|.|||..|| |..|.|.||.|||||||.
PFHELGEPQAAMFKVGMYKKHPEIPEELSAECKNFILRCFEPDPCKRASAQDLLQDPFL
Kinase nsy-1.AA STE11 664-925 44 1.8e-158 532.77 In-house 1-303 (303) Show / Hide 
Range on Protein: 664-925
Range on HMM: 1-303/303
Sequence Identity: 44% (135 aa)

SNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDE--------EVQP------LMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGG
 ... ..|||..||||.....||.. ..||.||.. ..        |.|.      ..|||.|...|.| |||.|.|| |   |..|||. ||||..|||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLH--DNQNDHVNIFMEYCPGG

SLSSLLRSKWGP--MNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTET----------FTGTLQ------
||||.||.||||  ..|. . .| |||||||.|||. .|.||||||.|.|......|||..|||..||||. .. |..          .|||..      
SLSSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGT

--YMAPEVIDHGQRG-YGAPADIWSFGCTMVEMATGRPPFVEMQN-PQAAMFRVGMF-KTHPPIPTEIT------EKCRNFIKSCFLPEACDRPSAKDLL
  .||||||....|. ||..|||||.|||..|||||.||. .... ..||||..||. |.||||| ...      |.||.|.. || .. ..||.| .||
PMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLL

QDPFI
|.|||
QHPFI
Kinase nsy-1.AA STE 665-925 27 2.6e-107 362.81 In-house 1-359 (359) Show / Hide 
Range on Protein: 665-925
Range on HMM: 1-359/359
Sequence Identity: 27% (99 aa)

NER-VVLGKGTYGTVYAARDM------DTQRQ---------IVVKEIEVKYD-----------------EEVQPLMEEISLHSTLC--HANIVQYLGCDL
 |.  ..|||..|||| |...      .|...         . .|..... .                 ||.| ...||.... .   | |||.|.|| .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VGK--DGSNDHFLIFMEHVPGGSLSSLLRSKW-------------GPMNENAMNYYGKQILEG-LKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTC
..   ....|.  |.||...||||......|.             ....|.   |. .|||.| |.|||...|.|||||..|.|.      .|..|||.|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVC

KRLAGLNP----------------VTETFTGTLQYMAPEVIDHGQRG----YGAPADIWSFGCTMVEMATGRPPFVEMQNP---QAAMFRVGMF------
..|.  ..                 . ||.||  .||||||. ...|    |.. .||||.|||..|||||.||. .|...    ...|  .|.      
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----KTHPPIPTEIT-------------------EKCRNFIKSCFLPEACDRPSAKDLLQ--DPFI
    ...||.|...                    .....||. |.  .  .||.|..||.   |||
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase nsy-1.AA STE11-Unclassified 667-925 35 1.2e-91 310.78 In-house 4-308 (308) Show / Hide 
Range on Protein: 667-925
Range on HMM: 4-308/308
Sequence Identity: 35% (109 aa)

RVVLGKGTYGTVYAARDMDTQRQIVVKEIEV-KYD-------EE-VQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRS
. ..|||..|.|| . . .|   ..||.||. .|.       .| .| . .|...  .| | |||||.|| .   . ..|.  |||| .||||..|.|. 
GEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEI---HKHEDCINIFMEYMPGGSIWSMLN-

KWGPMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLA------------------GLN-PVTE------TFTGTLQ-
| |. .|.    | |||||||.|||. .|.||||||.|.|. .  |.||..|||. |  .                   .  .. .      .  ||.. 
KYGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDF-DGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQGTPYQ

--YMAPEVID-HGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQN--PQAAMFRVGMFKTHPPIPTE-----------ITEKCRNFIKSCFLPEACDRPS
  .||||||.   | |... .||||.|||..|||||..|.   ||  ...|.. ..| .. |.||.            |...|..|.  ||     .||.
PFWMAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKKRPT

AKDLLQDPFI
|  |||.|||
ANQLLQHPFI
Kinase nsy-1.AA S_TKc 664-925 28 2.3e-88 300.77 SMART 1-231 (231) Show / Hide 
Range on Protein: 664-925
Range on HMM: 1-231/231
Sequence Identity: 28% (79 aa)

SNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPG--GSLSSLLRSKWGP
     ..|||..|.|| .|. .|.|.  .|.|        . .. ||....   | |||.....         ||. ..||...|  |.| ...... ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----MNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVIDHGQRGYGA-PADIWSFG
     ..|    .| .||...|.|.|...|.|||.| .|.|...   . ||.||| ...|        || ||. ||||||.     |||  ..|.||.|
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCG

CTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQ-------DPFI
|.. ||..|.|||      ...||.. .           .. ...||. |.  .  .||.| ..||       .|..
CILYEMLCGYPPFP----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase nsy-1.AA Pkinase 664-925 29 7.1e-78 269.83 Pfam 1-293 (293) Show / Hide 
Range on Protein: 664-925
Range on HMM: 1-293/293
Sequence Identity: 29% (89 aa)

SNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLME----EISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGG----SLSSLL
     ..|.|..|.|| ... .|... .||.|... ... ..       ||...  |.| |||.....        .||  . ||...||    .|....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDYI

R-SKWGPM--NENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVC----KISDFGTCKRL-AGLNPVTETFTGTLQYMAPEVIDHGQRGYGA
. .. |..   |.    | .|||.||.|.|. .|.|||.| .|.|..   |..    ||.||| .| .    |. . ||.||. |||||||  |...|| 
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGP

PADIWSFGCTMVEMATGRPPFVEM-----QNPQAAMFRVGMFKTHPPIPTEIT-------------------EKCRNFIKSCFLPEACDRPSAKDLLQDP
..|.||.||.. ||..||||| .       .... ..|... ..| ..|....                   | |. |||.|. .   .||.|...||.|
KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

FI
..
WF
Kinase nsy-1.AA MEKK2 665-925 42 1.2e-67 231.02 In-house 2-262 (262) Show / Hide 
Range on Protein: 665-925
Range on HMM: 2-262/262
Sequence Identity: 42% (113 aa)

NERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDE-----EVQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKW
    .||.| .| ||   |.|| | . || ...  |.     ||| |  || |   | |  |||| || |  .|  .    ||||..||||.   |.  .
RRGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFDPDNPETRKEVQALECEIQLLKNLQHERIVQYYGC-L--RDNQEKTLSIFMEYMPGGSVKDQLKA-Y

GPMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVT---ETFTGTLQYMAPEVIDHGQRGYGAPADIWSFGC
|.. |.    | .|||||..|||.  |||||||| |.| .  ||  |..|||  |||  .        . |||  .|.||||.    |||  ||.|| ||
GALTETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDS-SGNVKLGDFGASKRLQTICMHITGMKSVTGTPYWMSPEVIN--GEGYGRKADVWSIGC

TMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFI
|.||| | .||. |     ||.|..   .| | .| .. .. |.|.| ||     |||||..||.  |.
TVVEMLTEKPPWAEYEA-MAAIFKIATQPTNPQLPQHVSQHARDFLKRCFVEIKQDRPSAEELLRHHFV
Kinase nsy-1.AA STE20 659-925 34 2.6e-67 229.96 In-house 1-288 (288) Show / Hide 
Range on Protein: 659-925
Range on HMM: 1-288/288
Sequence Identity: 34% (102 aa)

YELSNSNERVVLGKGTYGTVYAARDMDTQRQ----IVVKEIEVKYD----EEVQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGS
|||       ..|.|.||.|| |.. .|...    . .| .... .    .|.. .. |||  . . | |||.|.|. |....  .|.  | ||.  |||
YEL-----LEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTC-DDELWIVMEYCGGGS

LSSLLRS--KWG------PMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAG-----LNPVTETFTGTLQYMAPEV
|. ...   |.|      ||||    |  ...|.||.|||. .|.|||||.||.|... .| .|..||| |  |        ..   || ||  .|||||
LTDIMKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTE-DGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEV

IDHGQ---RGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPP---I--PTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFI
|   .    ||.  .||||.| |  |||.|.||. .| .|  |||..   .  ||      |.  . . ..|...|   .  .||.|..||. |||
IQCMEGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDM-HPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase nsy-1.AA MEKK15 665-925 41 3.1e-67 229.68 In-house 2-264 (264) Show / Hide 
Range on Protein: 665-925
Range on HMM: 2-264/264
Sequence Identity: 41% (114 aa)

NERVVLGKGTYGTVYAARDMDTQ----RQIVVKEIE-VKYDEEVQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKW
    .|||| |||||       |    .|. . ||.  | ... . | ||. |  || | ||| |||  |      .    |||. |||||.||..  ..
KKGNILGKGAYGTVYCGLTNTGQLIAVKQVELDEIDKEKAKQQYRKLQEEVDLLKTLKHKNIVAYLGVCL-----EDNVVNIFMQFVPGGSISSII-NRF

GPMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLA--GLNPVT----ETFTGTLQYMAPEVIDHGQRGYGAPADIWS
||..|     | ||||.| .||||  .||||||| ||..    |. |. |||  |||.  |.|           ||  .||||||     |||  .||||
GPLDEMVFCKYTKQILQGVQYLHENCVVHRDIKGNNVMLMP-TGIIKLIDFGCAKRLCWQGINRTHSDMLKSMRGTPYWMAPEVIM--ETGYGRKSDIWS

FGCTMVEMATGRPPFVEMQNPQAAMFRVGMF-KTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFI
 |||. ||||..||. .|. . |||| .|      |..|    |. |.|.. |   .  .||.| .||. |||
IGCTVFEMATRKPPWADMD-RMAAMFYIGAHRDPMPQLPVKFSEDARMFVRMCLTRDQHERPTASQLLKHPFI
Kinase nsy-1.AA CAMK 669-925 16 1.4e-60 193.61 In-house 1-425 (425) Show / Hide 
Range on Protein: 669-925
Range on HMM: 1-425/425
Sequence Identity: 16% (70 aa)

VLGKGTYGTVYAARDMDTQ------------RQIVVKEIEVK----------------------------YDEEVQPLMEEISLHST-------LCHANI
.||.|..|.|. ...  |.            ..  .| |. |                             ..  . .. ||.....       | | ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQYLGCDLVGKDGS--------------NDHFLIFM---EHVPGG----SLSSLLRSK--------------WGPMNENAMNYYGKQILEGLKYLHELKI
.. .     .. ..              ..|. ..|   |...||     | . ....              .| ..|    .| .||.....|.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDIKGDNVLVNTYS----------------GVCKISDFGTCKRLAGL-----------------------NPVTETFTGTLQYMA-PEVIDH-G----
||||.| .|.|... .                .  ||.|||  ... .                        ..  .|| ||. ||| |||.   |    
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------QRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAA--------------MFRVGMFK-THPPIPT-------------------EITEKCRN
       ...|| ..|.|| |. .  | .|.||| .  . .                . . | .   .|....                   .... |..
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FIKSCFLPEACDRPSAKDLLQDPFI
.|...  ..  .|..... |..|..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase nsy-1.AA Dicty2 659-925 36 4e-51 176.17 In-house 1-264 (264) Show / Hide 
Range on Protein: 659-925
Range on HMM: 1-264/264
Sequence Identity: 36% (100 aa)

YELSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIE-----VKYDEE-VQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLS
| ..     ...|||  |||| . .  |      | |.     .| .||  | .| || |  .| |.||| |..   .      .|  |..| . .||||
YQIGD----EKIGKGAFGTVYKGLHIETGDFVAIKQINIMKKKTKISEEQHQSIMQEIHLLKKLNHHNIVKYIEHIET-----ENHLYIILEYIENGSLS

SLLRSKWGPMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTY--SGVCKISDFGTCKRLA-GLNPVTETFTGTLQYMAPEVIDHGQRGYGAPA
  .  | |.  |     | .|.|.|| |||. ...|||||..| |...   ||| | .|||..  ..        |. ||   ||||||           
KIIK-KFGCFPESLCCIYIYQVLKGLVYLHRQGVIHRDIKAANILITKEGKSGVIKLADFGVATHIDYSDDDSRYTVVGTPYWMAPEVIQMSGNHCCTAC

DIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFI
|||| |||. |. || ||     || .||||      |||.|. |.  | .|   ||  .   |..|| ||. | |
DIWSLGCTIIELLTGNPPYWDL-NPMHAMFRM-VQDDHPPLPNDISPECKDFLMQCFCKDPNQRMTAKQLLHHPWI
Kinase nsy-1.AA STE-Unique 741-925 25 4.2e-40 139.54 In-house 371-616 (616) Show / Hide 
Range on Protein: 741-925
Range on HMM: 371-616/616
Sequence Identity: 25% (63 aa)

IFMEHVPGGSLSSLLRSKWGP--------MNENAMNYYGKQILEGLKYLHELK--IVHRDIKGDNVLVNTYS----GVCKISDFGTCKRLAGL-------
||||  ..|.|. .. .  .|        . |    .| .|||||| |||  .  |.|||.| .|.. .          ||.|||. ....         
IFMEYCEHGTLQQIIKRCGCPGNPNNLQLFPETEVIWYTYQILEGLEYLHSQHNPIIHRDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPDHFEKDNN

-------------------------------NPVTETFTGTLQYMAPEVIDHG---QRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQA-AMFRVGMF
                               |    .  ||  ||.||||        .|.. .||||.||.. .|..| ||... .. || .  .    
SKNSNTWININNNSSTNSTAQQTPMWDLNINNYTMKYCCGTPCYMCPEVINCRNQINNPYDTKVDIWSLGCMCFHMCCGCPPWHQRYHMQAYIEMCIHIH

KTHP-----PIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFI
.  |     .||   .   . || .|. ..  .||||..||.... 
CQPPQCPIENIPPKCQPEQQQFIEKCLERNPHHRPSAHQLLHHFWL
Kinase nsy-1.AA Pkinase_Tyr 669-811 28 7.3e-22 74.66 Pfam 6-156 (270) Show / Hide 
Range on Protein: 669-811
Range on HMM: 6-156/270
Sequence Identity: 28% (44 aa)

VLGKGTYGTVYAARDM----DTQRQIVVKEIEVKYDEE---VQPLMEEISLHSTL-CHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSK--
.||.| .|.|| ..      .|. .  || .  ....|    . .|.|... ..|  | |||...|. .  .. .  . .| ||..|.|.| . ||..  
KLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLDYLRKHRE

-WGPMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFG
  .| .   .  .  || .|. ||.. ...|||.   |.||.  ..|.||.|||
DKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-NNVVKICDFG
Kinase nsy-1.AA TyrKc 664-923 24 8e-17 49.27 SMART 1-280 (280) Show / Hide 
Range on Protein: 664-923
Range on HMM: 1-280/280
Sequence Identity: 24% (71 aa)

SNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTL--CHANIVQYLGCDLVGKDGSN----DHFLIFMEHVPGGSLSSLLRS
     .|| | .|.|| ..     .|  || .       .. .|.|... . |   | |||. .|.  . ..| |    .  .| ||..|.|.| . ||.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGV--CTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KWGPMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAG---------LNPV----TETFTGTLQYMAPEVIDHGQRG
. .  .   . ..  || .|  |||. ...|||.   |.||.    ..|||||| .. .              .     . .   .  ||||.|..|   
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK--

YGAPADIWSFGCTMVEMAT-GRPPFVEM----QNPQAAMFRVGMFKTHPPIPT-------EITEKCRNFIKSCFLPEACDRPSAKDLLQDP
.    |.|||| .| |. | | .|  .|     ..| .. .|   .  |. |        . ...  . .|.|   .. |||. ... .. 
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase nsy-1.AA STE-Unique 665-740 23 2.4e-11 36.01 In-house 1-102 (616) Show / Hide 
Range on Protein: 665-740
Range on HMM: 1-102/616
Sequence Identity: 23% (24 aa)

NERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEE------VQPLMEEISLHSTLCHANIVQYLGCDLVG--------------------KDGSNDH
|. . .|.|  |.|. .... . ..  .| |..|          |... .|| ... | | ||| |.|  | |                     | | | 
NCQQMIGRGSFGNVHNCQNKKDCFRCAIKVIHLKQFKDFNQEPLVNMIISEIEIMKCLHHQNIVKYYGHWLWGGCDSFQSLEEGNEDLSGDLETDASEDW

FL
|.
FM
Kinase nsy-1.AA Pkinase_Tyr 833-875 40 5.4e-07 24.31 Pfam 181-223 (270) Show / Hide 
Range on Protein: 833-875
Range on HMM: 181-223/270
Sequence Identity: 40% (18 aa)

MAPEVIDHGQRGYGAPADIWSFGCTMVEMAT-GRPP-FVEMQNPQ
||||.| .|   .    |.|||| .| |. | |. | . .| | .
MAPECINYGK--FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEE
Sam7 nsy-1.AA sam7 1302-1364 17 2e-09 31.45 In-house 1-70 (70) Show / Hide 
Range on Protein: 1302-1364
Range on HMM: 1-70/70
Sequence Identity: 17% (12 aa)

LLQEELVSWLRGLEI--DERSIALIASEAY----TKSDMMDFVTRDELLSIGV-GGGSSCRIMRAIGEVR
  .|... ||....   ... .  . .. .    |  |... .|...|...|.  .|  ..|...|   |
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR