Gene pct-1 (Nematode worm)

pct-1

Species: Nematode worm
Alias: pct-1, C07G1.3, CE06779, C07G1.3a, aSWK169, C07G1.3A
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: IV: 8176472-8188869, WormBase Genetic Map location: IV:3.68,

Classification

Group: CMGC
Family: CDK
Subfamily: PFTAIRE

Sequence

Name Sequence Type Origin Length Description Download
pct-1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 282 Kinase domain by global Sugen HMM Fasta, JSON
pct-1.AA Protein Genbank 577 None Fasta, JSON

Protein domain

Protein domains of pct-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase pct-1.AA PFTAIRE 238-519 65 3e-223 747.96 In-house 1-287 (287) Show / Hide 
Range on Protein: 238-519
Range on HMM: 1-287/287
Sequence Identity: 65% (188 aa)

YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEEGAPCTAIREVSLLRNLRHANVVTLHDIIHTDRLLTLVFEYVDRDLKQYMDSCNNAMQMNNIR
||||.|||||.||||..|.|.....|||||||||.||||.|.|||||.|||.||.|||.|.|||||||...||.|||||..||.||||.....|..||.|
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQQEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPGGMHPNNVR

LFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMIAGRALFPG
|||.||||||.|||||||||||||||||||...|||||||||||||||||..|||.|||||||||||||||||.||||.||||||||..||..|...|||
LFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPAFPG

G-TPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANR--HYNPDPLCRQIPRID--AHGFELLMKFLQYEGKDRVSAAEAVKHPFL
. ..|.||..||..||.|..|..|..|..|...|...|  .|.|..||.|.|||.  .|...|.||.||.|..|||||.||..||..
MKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase pct-1.AA PCTAIRE 238-519 66 1.4e-190 639.43 In-house 1-291 (291) Show / Hide 
Range on Protein: 238-519
Range on HMM: 1-291/291
Sequence Identity: 66% (193 aa)

YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEEGAPCTAIREVSLLRNLRHANVVTLHDIIHTDRLLTLVFEYVDRDLKQYMDSCNNAMQMNNIR
| |||||||||||||...|| ||.  ||||||||| |||||||||||||||..|.|||.|||||||||.. ||||||| |.||||||| | | |.|.|..
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTHHQLTLVFEYMDMDLKQYMDDCGNIMNMHNVK

LFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMIAGRALFPG
|||.||||||||||.|..||||||||||||  .||||||||||||||||||||||.|||||||||||||.||||||| |||||||||..|| .||.||||
LFLFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTGRPLFPG

GT------PTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANRHYNPDPLCRQIPRID---AHGFELLMKFLQYEGKDRVSAAEAVKHPFL
 |        .|| .||| || |     | .   . | .|    | . ||    ||.|     . .|| ..||||.| ||||..|.|||. 
STDSHYPGVKDQLHMIFRILGTPDEKTWPGVKSNEEFRTYNFPRYREQPLINHAPRLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPYF
Kinase pct-1.AA CDK 238-519 43 4.4e-166 535.49 In-house 1-284 (284) Show / Hide 
Range on Protein: 238-519
Range on HMM: 1-284/284
Sequence Identity: 43% (140 aa)

YEKLDKLGEGTYATVFRGRSILTN-----KFVALKEIRLEQ-----E-EGAPCTAIREVSLLRNLRHANVVTLHDIIHTD-----------RLLTLVFEY
||||.|.|||||..|...|. .|.     ..||||.||.|.     | || |.|||||.|||..| |.|.|.|||..||.           . |..||||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

VDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGE-----LKLADFGLARAKSV------PTKTYSNEVVTLWYRPPD
.| |||.|||          |. ...||||||.|||.....||||||||.||. .||     ||.||||||||...      |..||..||||||||.|.
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

VLLGSTDYS--THIDMWGVGCILFEMIA---GRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANRHYNPDPLCRQIPRIDAHGFELLMKF
.||||..||  | ||||.||||. ||.    ...|||| . ..|| .|||..|.| .|  | ... | .                         .||.|.
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNKM

LQYEGKDRVSAAEAVKHPFL
|.|. | |.|| .| .||..
LCYDPKKRISAEQALQHPYF
Kinase pct-1.AA CDK5 238-519 54 1.1e-160 511.88 In-house 1-287 (287) Show / Hide 
Range on Protein: 238-519
Range on HMM: 1-287/287
Sequence Identity: 54% (156 aa)

YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQE-EGAPCTAIREVSLLRNLRHANVVTLHDIIHTDRLLTLVFEYVDRDLKQYMDSCNNAMQMNNI
|||..|.|||||.||...|   |  .||||..||..| || |.|||||..||. |.| |.| |||.||... ||||||..| ||| ||||||  |.|. |
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

RLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMI-AGRALF
. |.||||.|||.||...|||||||||||||  .|||||||||||||  .| ..|| |||||||||||||.||  ||| |||| .|||. ||. ||| ||
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF

PGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFY--PYANRHYNPDP-LCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFL
||   ..|| .||. .|.|  |. | | . | .     .   |.. . .   .|. |..| .|| | ||.. . |.||..| .||. 
PGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase pct-1.AA CDC2 238-519 46 1.6e-139 431.76 In-house 1-301 (301) Show / Hide 
Range on Protein: 238-519
Range on HMM: 1-301/301
Sequence Identity: 46% (140 aa)

YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLE-QEEG--APCTAIREVSLLRNLR-HANVVTLHDIIHTDRLLTLVFEYVDRDLKQYMD---SCNNA
|.|. |.|||||  |....   ||. |||| |||| ..||   | ||||| |.| .|. | |.|.|||.||  . | .||||.|.|||.|||   . |  
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

MQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYS--NEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEM
|. .... ..||.|.|...|||||..||||||||.|| .||..|.|||||||| ..| .||    ||||||||.| .|||. .||| .||| .|||. ||
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---IAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANRHYNPDPLCRQIPR---------IDAHGFELLMKFLQYEGKDRVSAAEAVKH
   .  ..||.|    .||  |||.||.|  .  | ... | ...   | ..|  | ...|.         .|  |..|||. |||.  .|.|| || .|
FMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPR-WKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQH

PFL
|..
PYF
Kinase pct-1.AA CMGC 238-519 23 1.7e-127 421.41 In-house 1-513 (513) Show / Hide 
Range on Protein: 238-519
Range on HMM: 1-513/513
Sequence Identity: 23% (122 aa)

YEKLDKLGEGTYATVFRGRSILTN--------------KFVALKEIRLE----------QEEGAPCTAIREVSLLRNLR-----------------HANV
||...|.|||||..|...|  .||              ..||.| |...           ..| |..|.||...|..|.                 | |.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VTLHDIIHTDR-----------------LLTLVFEYVDRDLKQYMDSCN------NAMQM-------------NNIRLFL------YQLLRGLA--YCHQ
|.|.||....                   | |||||.| ||.||.....      . | .             .||. |.      ||.||||.  |||.
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHS

RR--VLHRDLKPQNLLITAKGEL--------------------KLADFGLARAKSVP---------------------TKTYSNEVVTLWYRPPDVLLGS
..  ..||||||.|.||. ..||                    |..||||||. ...                     ...|...|||.|||.| .|||.
HWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGW

TDYS---------THIDMWGVGCILFEMIAG--------RALFPGGTP-----------TEQLGLIFRTLGSPR---------------PDRHPTICEKP
..|.         | ||||.||||..||. |        . |||| .             .|| .||..||.|                ..  |.. ..|
KHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLP

TF---------------YP------------YANRHY-NPDPLCRQIPR--------------------------------IDAHGFELLMKFLQYEGKD
..               ..            . .... .  .|.  .|.                                .|  ...||.| |||. ..
WYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDK

RVSAAEAVKHPFL
| .|..| .||..
RITAEQALQHPYF
Kinase pct-1.AA S_TKc 238-519 27 1.3e-93 318.21 SMART 1-231 (231) Show / Hide 
Range on Protein: 238-519
Range on HMM: 1-231/231
Sequence Identity: 27% (81 aa)

YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEEGAPCTAIREVSLLRNLRHANVVTLHDIIHTDRLLTLVFEYVDR---DLKQYMDSCNNA----
||.|.|.|.|....|...| . |.. ||.|.|.        ....||...|.. .| |.|.|.|....   | .|.||.|    ||..|.....      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-MQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYST-HIDMWGVGCILFEM
 .    .| ..||....|.|||.....||||||.|.|..   ..|..||||||         .  ..|.||..| ||     |..  .|.| .||||.||
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEM

IAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANRHYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVK-------HPFL
..|. .||      |. ..|. .|                                    .  . ....| ||.. ..| .| || .       ||..
LCGYPPFP------QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase pct-1.AA Pkinase 238-519 28 2.2e-86 298.12 Pfam 1-293 (293) Show / Hide 
Range on Protein: 238-519
Range on HMM: 1-293/293
Sequence Identity: 28% (87 aa)

YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEEG-APCTAIR--EVSLLRNLRHANVVTLHDIIHTDRLLTLVFEYVDRDLKQYMDSC-------
|... |.|.|....|.... . |.| ||.|.|... |.   . |..|  |......|.| |.|.|.|. .... . .|.||.. .|.  || .       
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWR

NNAM--QMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGEL----KLADFGLARAK-SVPTKTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWG
....  ... .. ..||.||||.|||.....||||||.|.||  .|..    |..|||||. .   .   ..  ..|.||..| |..|...|.. .|||.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

VGCILFEMIAGRALFPGG----TPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANRHYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKH
.||||.||. || .|||     .  .|. .|.|..| | .   |. |....|.   .. . .. . .  ....  . ... . |..  |.| .|.....|
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF--FRH-W-HF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQH

PFL
|..
PWF
Kinase pct-1.AA PITSLRE 238-519 38 4.5e-86 292.27 In-house 1-295 (295) Show / Hide 
Range on Protein: 238-519
Range on HMM: 1-295/295
Sequence Identity: 38% (114 aa)

YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLE--QE-EGAPCTAIREVS-LLRNLRHANVVTLHDII--HTDRLLTLVFEYVDRDLKQYMDSCN---
...|.. .||||  |.|..  .|.  |||| . .|  .| || | |..||.. .|. |.| |.|..  |.   .     .|.|||. |||  |.  .   
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

NAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEM
   .   |  .. ||||| .. |   ..|||||  |||.. || ||..||||||    | | |.  ||||||| | .|||.  ||| .||| ||||. |.
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEF

IAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYA-NRHYNPDPLCRQIP---RIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFL
| .. ||.|   ..|.  ||  .| |     | . | | .      .|| .  | . .|   .|   ||.|| ..| |  | | .| .| |||. 
ITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase pct-1.AA CDK4 238-519 41 3.9e-85 289.15 In-house 1-290 (290) Show / Hide 
Range on Protein: 238-519
Range on HMM: 1-290/290
Sequence Identity: 41% (124 aa)

YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLE-QEE--GAPCTAIREVSLLRNLR---HANVVTLHDIIH---TDR---LLTLVFEYVDRDLKQYMD
|...  .||| | ||.| |.. | .||||| .|   .||  | |   |||.|..| |    |.|.| | |. |   |||   ..|.||| .| ||..|.|
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD

SCNN-AMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCI
 |    |    |.    |||||. . |  |. ||||||||.|.|  |..|||||||||  |  ..  .  ||||||| | ||| |. | | .||| ||||
KCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQMALTPV-VVTLWYRAPEVLLQSY-YNTPVDMWSVGCI

LFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHP-TICEKPTFYPYANRHYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFL
 .||   |.||.|    .||. ||   | |  |  | ..         . . . | |.    | ..  | .|| | | |. . |.|| .. .||..
FAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDVS----LPWDHFPQRHPRPFKDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase pct-1.AA CRK7 238-519 31 1.3e-84 287.37 In-house 1-343 (343) Show / Hide 
Range on Protein: 238-519
Range on HMM: 1-343/343
Sequence Identity: 31% (108 aa)

YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQE----EGAPCTAIREVSLLRNLRHANVVTLHDIIHTD---------R-LLTLVFEYVDRDLKQY
||...  |||||  |   .   |.. |||| .|.. |    || | |||||. .|| | |.|.|.|..|.  .         .    .||||.| ||   
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

MDSC-NNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGELKLADFGLARAKSVPT--KTYSNEVVTLWYRPPDVLLGSTDY--------
..|        .... |. ||| |..|||.. .||||.|  |.|.  .||.|.|||||||        . | | |.|||||||  ||| . |        
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE

------------------------------STHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANRHYNPDPLC
                               . ||||..|||| |   ....|.|    .|| .|..  ||| |.  |.. . | .     .      | 
LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRLR

RQIP------RIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFL
 .         ...  . || | | .  | |..| |.  |...
EEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase pct-1.AA CDK10 238-519 36 1.9e-76 260.28 In-house 1-285 (285) Show / Hide 
Range on Protein: 238-519
Range on HMM: 1-285/285
Sequence Identity: 36% (105 aa)

YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQE-EGAPCTAIREVSLLRNLRHANVVTLHDIIHTDRL--LTLVFEYVDRDLKQYMDSCNNAMQMN
.||| ..|||||  |.| | . ..  |||| .|...| .| |  ..||. || ..|| |.| ||...  . |  . || .| . ||   .|   .     
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHLDSIFLVMQYCEQDLASLLDNMPQPFTET

NIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMIAGRAL
...    |.|||| | |.. ..|||||  |||.| || .|.|||||||. .|| |     .|||||| |..|||...  | |||| ||||| |..... |
QVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELLVHKPL

FPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANRHYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFL
.||     |. .|   ||.|     |   . |    .. ..     |  . . .   | .||   . |. | |  | |...  . 
MPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYNNLKHKFHWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF
Kinase pct-1.AA Pkinase_Tyr 238-383 27 1.2e-15 53.57 Pfam 1-160 (270) Show / Hide 
Range on Protein: 238-383
Range on HMM: 1-160/270
Sequence Identity: 27% (45 aa)

YEKLDKLGEGTYATVFRGRSI----LTNKFVALKEIRLEQEEGAPCTA------IREVSLLRNL-RHANVVTLHDIIH-TDRL--LTLVFEYVDR-DLKQ
 ... ||||| . .|..|.       |.  || | ..    |||   .      .||......| .| |.| |. ..   ..   . .|.||.   ||. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

YMDSC---NNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGELKLADFGLARA
|  .    ...  |  .  . .|  .|..| ....  ||||   | |.| ..  | .||||||.
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD
Kinase pct-1.AA TyrKc 238-519 18 8.1e-14 0.73 SMART 1-280 (280) Show / Hide 
Range on Protein: 238-519
Range on HMM: 1-280/280
Sequence Identity: 18% (59 aa)

YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEEGAPCTAI-REVSLLRNL--RHANVVTLHDIIHTD-------RLLTLVFEYVDR-DLKQYMDS
 ....||||| . .|..|. .     || | .. .        .. || .....|  .| |.| |. .. ..         | .|.||..  |||.|  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

CNNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGELKLADFGLARAKSVP------TKTYS-----NEV--VTLWYRPPDVLLGSTD-Y
. .  .|     | .|  .| .| |.... ||||   | |.....  | .||||.|.          ...|.     ..   . .   .| ..   .  .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKF

STHIDMWGVGCILFEMIAGRALFPGG------TPTEQLGLIFRTLGSPRPDRH-PTICEKPTFYPYANRHYNPDPLCRQIPRIDAHGFELLMKFLQYEGK
.|  | |  |  ..|.    .  . |      ...| . .. .    |.|. . | .                       ..  .  ...  .  ... .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MS---------------------FVCCPDEMYQIMKQCWHEDPE

DRVSAAEAVKHPFL
|| . .|   | ..
DRPTFSEI--HECF