Gene pik-1 (Nematode worm)

pik-1

Species: Nematode worm
Alias: CE31033, aSWK414, pik-1, K09B11.1
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: IV: 13416764-13421499, WormBase Genetic Map location: n/a,

Classification

Group: TKL
Family: IRAK

Sequence

Name Sequence Type Origin Length Description Download
pik-1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 292 Kinase domain by global Sugen HMM Fasta, JSON
pik-1.AA Protein Genbank 485 None Fasta, JSON

Protein domain

Protein domains of pik-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Death pik-1.AA Death 22-100 17 3.5e-14 49.88 Pfam 1-87 (87) Show / Hide 
Range on Protein: 22-100
Range on HMM: 1-87/87
Sequence Identity: 17% (15 aa)

QQICAIL----DTDNTWETIAPY--MPGIELRDVEGCKRYSSYNQSPSELLLRIWSSK---GYSTTHLYQLFAKTKLIRLMRMMRSQV
|..|..|    .. . |.. |..  |.  |.. .| . ... ...|... .|..|. .   ...  ||.... | ..........| .
QKLCRLLDPDHHPGKDWRRLARKLGMSDNEIDQIEHD-QNPHDLRSQTYQMLWKWEQRHGKNATVDHLIEALRKMGRRDCAEKIQSWL
Kinase pik-1.AA IRAK 185-472 42 1.1e-170 573.29 In-house 1-317 (317) Show / Hide 
Range on Protein: 185-472
Range on HMM: 1-317/317
Sequence Identity: 42% (136 aa)

FAVSNVIGKGGYGTVYKGELKGTGGIVAVKRLHSGNDTSQNGSRERLRQSLTELRTLARFRHDNILPIYAYSLEGSEPCLVYQFMSNGSLEDRLLCRKGS
|...|.||.||.|.||.|..|.|.||.|||.|....|.|.|....|..||..||....|.||.||.|.|.|..|....||||..|.|||||||| |..|.
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

VP---LTWIQRKEISIGAGRGLGFLHSFG-KTPIIHGDIKTANILLDKHMEPKIGDFGLCRDGHVEAEAMEKHPL---IASHIKGTLAYLAPEFIT--SK
.|   |.|.||..|..|...|..|||... .|||||||||.||||||.|..|||.||||.|.|| .|...||...   ..||..||..|..||||.  ..
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGH-PASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQG

ILTTKLDVYSFGIVLLEIASGQ-RAYSDSRETRGLVEYCQVNKELAAH--------------------RKIPVREIFIDRRAPPLVGDEEKSFLDALIEV
.||.|.|||||||||||...|. ..|.|..|...|...|....| ..|                    |.....|.|||.|.||.....||.........
QLTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHRMPPCPPNMEKEMCQCACCC

GLAGANNDRKVRPTMSQI
|...||........|.|.
GHHRANRRCDMAWVMQQL
Kinase pik-1.AA TKL 191-476 22 2.1e-75 256.8 In-house 1-364 (364) Show / Hide 
Range on Protein: 191-476
Range on HMM: 1-364/364
Sequence Identity: 22% (85 aa)

IGKGGYGTVYKGELKG--------TGGIVAVKRLHSGNDTS--------------------QNGSRERLRQSLTELRTLARFRHDNILPIYAYSLEGSE-
||.||.|.||||...|        ||  ||||...| || .                    .. ..    .   |.. . |.||.||.....|.....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PCLVYQFMSNGSLEDRLLCRKGSVPLTWIQRKEISIGAGRGLGFLHSFG-----KTPIIHGDIKTANILLDKHME-------------
            .|.|......|||...|.         | ||  ..... ||. .||| .     | |||| |.|..|||.|....             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-PKIGDFGLCRDGHVEA--EAMEKHPL----------IASHIKGTLAYLAPEFITSK----------------ILTTKLDVYSFGIVLLEIASGQRAYSD
 .||.||||.|. . .   ......              ... ||....||| .  .                  ..| ||||||||| ||....| |.|
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

SRETRGLVEYCQVNKELAAHRKIPVREIFID-----RRAPPLVGDEEKSFLDALIEVGLAGANNDRKVRPTMSQIVEYL
  .   ..   .  .| .. .    .   |.     ..  . .   ...... ...      . | . ||....|...|
YPYMPMIFQD-P-FEEMFMMVCDKGLRPPIPPIWQNHH--K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase pik-1.AA Pkinase 185-397 29 3.9e-42 150.05 Pfam 1-209 (293) Show / Hide 
Range on Protein: 185-397
Range on HMM: 1-209/293
Sequence Identity: 29% (65 aa)

FAVSNVIGKGGYGTVYKGELKGTGGIVAVKRLHSGNDTSQNGSRERLRQSLTELRTLARFRHDNILPIYAYSLEGSEPCLVYQFMSNG----SLEDRLL-
. .  .||.|..|.|||.  |||| |||||..   .. |.   . |..   .|.. ..|..|.||. .| .  .......|  .. .|    .| |..  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL---SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

CRKGSVPLTWIQRKEISIGAGRGLGFLHSFGKTPIIHGDIKTANILLDKHMEP----KIGDFGLCRDGHVEAEAMEKHPLIASHIKGTLAYLAPEFIT-S
 |.|.. ... . | .     ||| ..||     ||| |.| .|||.|.....    ||.||||..         . .   .... ||. |.||| |  .
WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIRGG

KILTTKLDVYSFGIVLLEIASGQ
.  ..| |..|.|..| | ..|.
QYYGPKVDMWSCGCILYEMLCGR
Kinase pik-1.AA TKL-Unique 187-398 29 5e-40 138.88 In-house 1-226 (290) Show / Hide 
Range on Protein: 187-398
Range on HMM: 1-226/290
Sequence Identity: 29% (70 aa)

VSNVIGKGGYGTVYKGELKGTGGIVAVKRLHSGNDTSQNGSRERLRQSLTELRTLARFR-HDNILPIYAYSL----EGSEPCLVYQFMSNGSLEDRLLCR
..|.|| ||||.||||. .|.  .||.|..|  |  | | ... ..    |.... ... |.||. ...|.       .. |.|  ... ||| | .| .
FWNKIGEGGYGQVYKGKWRGY--PVAIKQFHP-NEDSSNEMMQEFEN---EVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYD-VLHQ

--------KGSVPLTWIQRKEISIGAGRGLGFLHSFGKTPIIHGDIKTANILLDKH-----MEPKIGDFGLCRDGHVEAEAMEKHPLIAS------HIKG
        . . .|.. ||  . | . .|. .||. ... |||.|.|. |.|.| .     .  || ||||..     .  . | ... .        .|
NNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSK----FNSKINKMTNNEHKGTRNQTRCG

TLAYLAPEFITS--KILTTKLDVYSFGIVLLEIASGQR
.. ..||| ...  .  ..| ||||||||| |||....
SFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKI
Kinase pik-1.AA S_TKc 185-476 22 8.3e-39 136.16 SMART 1-231 (231) Show / Hide 
Range on Protein: 185-476
Range on HMM: 1-231/231
Sequence Identity: 22% (68 aa)

FAVSNVIGKGGYGTVYKGELKGTGGIVAVKRLHSGNDTSQNGSRERLRQSLTELRTLARFRHDNILPIYAYSLEGSEPCLVYQFMSN--GSLEDRLLCRK
. . ..||||..|.|||.  |.|| |||.|...              .. . |.. | . .|.||  .| .  . .. ..|  ....  |.| |..  |.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

GS---VPLTWIQRKEISIGAGRGLGFLHSFGKTPIIHGDIKTANILLDKHMEPKIGDFGLCRDGHVEAEAMEKHPLIASHIKGTLAYLAPEFITSKILTT
.    .|..  . . .     ..| ..|| |   ||| |.| .|||||.  . ||.||||.|                ... ||. |.||| .     ..
RHGLRFPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGK

-KLDVYSFGIVLLEIASGQRAYSDSRETRGLVEYCQVNKELAAHRKIPVREIFIDRRAPPLVGDEEKSFLDALIEVGLAGANNDRKVRPTMSQIVE----
 | |..|.|..| | ..|.  ..       . .  .. .                        .| |.|.. . ..       | . |||  .. .    
CKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-----------------------SPEAKDFIRKCLQK-------DPEKRPTA-EALQDEWD

-----YL
     ..
IKCHPWF
Kinase pik-1.AA MLK 185-397 27 8.5e-32 107.64 In-house 1-233 (291) Show / Hide 
Range on Protein: 185-397
Range on HMM: 1-233/291
Sequence Identity: 27% (67 aa)

FAVSNVIGKGGYGTVYKGELKGTG---GIVAVKRLHSGNDTSQNGSRERLRQSLTELRTLARFRHDN----ILPIYAYSLE-GSEPCLVYQFMSNGSLED
. .. .||.|..| |.||. ...     |||||| ..  . .   . .  ..  .| | |....| |    | ..|. .|. ... |.| .....||| .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

RLLCRKG-----------SVPLTWIQRKEISIGAGRGLGFLHSFGKTPIIHGDIKTANILLD------KHMEPKIGDFGLCRDGHVE-AEAMEKHPLIAS
 |  ...           ..  .  .   ..    ||. .|||  . |||| |.|  |||.|      .|.  || |||. || |   .  | .      
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSN------

HIKGTLAYLAPEFI---TSKILTTKLDVYSFGIVLLEIASGQ
  .||.|. ||| |    .   . | ||.|.|.|| |. ...
--AGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase pik-1.AA TK 185-395 16 2.1e-31 101.95 In-house 1-389 (486) Show / Hide 
Range on Protein: 185-395
Range on HMM: 1-389/486
Sequence Identity: 16% (66 aa)

FAVSNVIGKGGYG---TVYKGELKGTGG-------------------------IVAVKRLHSGNDTSQNGSRER--------LRQSLTELRTLARFR---
  . ...|.| .|   .|||||..| ..                          |||| |..|...||.  ...        .   | |.. .. ..   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGE-DFLEEAEEMKMMCHSL

--HDNILPIYAYSLEG------------SEPCLVYQFMSNGS----LEDRLL-CRKGSVP----------------------------------------
  |.||. .|.....|              ...|  .|..|.    | | |  ||..  .                                        
GHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD

--------------------------------LTWIQRKEISIGAGRGLGFLHSF------GKTPIIHGDIKTANILLDKHME-----------PKIGDF
                                ||  |.  ..  . .|. .|||       .   ..|.|. . |.|.....             ||.||
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQN---FVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADF

G--------LCRDGHVEAEAMEKHPLIAS-------------------HIKGTLAYLAPEFITSKI---------LTTKLDVYSFGIVLLEIAS
|        |.|| . . .   |..  ..                     |  . ..||| .....          ||| ||.|||... || .
GLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase pik-1.AA RIPK 191-402 28 1.5e-30 101.31 In-house 1-230 (290) Show / Hide 
Range on Protein: 191-402
Range on HMM: 1-230/290
Sequence Identity: 28% (67 aa)

IGKGGYGTVYKGELKGTGGIVAVKRLHSGNDTSQNGSRERLRQSLTELRTLARFRHDNILPIYAYSLEG-----SE-PCLVYQFMSNGSLEDRLLCRKGS
.|.|| |.|.|   . . | ...|    .    .   ..   . . |   ... |...|.|||    .      .. . .| ..| ||||.. .| .| .
VGGGGFGEVFKARHR-HWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWH-FLHTKWP

-----VPLTWIQR--KEISIGAGRGLGFLHSFGKT-PIIHGDIKTANILLDKHMEPKIGDFGLCRDGHVEAEAMEKH-----PLIASHIK-GTLAYLAPE
     .|.    |  .|||     |  .|||  .. |||| | |..|||.| ..  || ||||  .        ...        .|  . |||.|..||
YQHHPDPWPLRCRMIHEISC----GMCYLHS--MNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPE

FIT-----S-KILTTKLDVYSFGIVLLEIASGQRAYSD
 .      . |. |.| |||||.||. |. ..  .|.|
HFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHPYED
Kinase pik-1.AA STE 185-402 24 1.9e-29 101.18 In-house 1-270 (359) Show / Hide 
Range on Protein: 185-402
Range on HMM: 1-270/359
Sequence Identity: 24% (71 aa)

FAVSNVIGKGGYGTVYKGELKG---------------TGGIVAVKRLHSGNDTS----------QNGSRERLRQSLTELRTLARFR--HDNILPIYAYSL
.    .||||..|||||.  .                || |.|.|...  |...          .|   | . | | |.... ...  |.||   | . .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EG-------SEPCLVYQFMSNGSLEDRLL-CRKGSVPLT----------WIQRKEISIGAGRG-LGFLHSFGKTPIIHGDIKTANILLDKHMEPKIGDFG
 .       .| ...  .|..|||.| .  . .   ||.            | . |     .| | .||| .   ||| ||| |||||      |. |||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LCR-------DGHVEAEAMEKHPLIAS------------HIKGTLAYLAPEFITS------KILTTKLDVYSFGIVLLEIASGQRAYSD
.|        ..   .        . .            .. ||  . ||| |.       |  .|| |..|.|....| | |.  ..|
VCGQLTDSMANI-Q-S-------NN-IIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHD
Kinase pik-1.AA LRRK 185-402 21 2e-27 94.11 In-house 1-285 (351) Show / Hide 
Range on Protein: 185-402
Range on HMM: 1-285/351
Sequence Identity: 21% (62 aa)

FAVSNVIGKGGYG-TVYKGELKG--------------------------TGGIVAVKRLHSG-------NDTSQN--------------------GSRER
.   . ||.||.| .||.....|                           .  ||.| .. .       .. | |                    .. . 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LRQSLTELRTLARFRHDNILPIYAYSLEGSEPCLVYQFMSNGSLEDRLLCRKGSV------PLTWIQRKEISIGAGRGLGFLHSFGKT-PIIHGDIKTAN
.|    |.  . ...|.||.... ....   .|.|  ....|.| ..|  .| .        ..|  . .|..   .|...|||  .. |||| | |. |
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS--HNPPIIHRDLKSPN

ILLDKHMEP------------KIGDFGLCRDGHVEAEAMEKHPLIASHIKGTLAYLAPEFIT---SKILTTKLDVYSFGIVLLEIASGQ-RAYSD
||| .....            ||.|||. |     .  |.    .|.   |.  ..||| .     .  |.| |.||||..| |. ..| ... .
ILLWSSPQNHSPNYPNAHVCAKIADFGISR-MF-QCFHMG----VAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDE
Kinase pik-1.AA Dicty4 185-397 30 1.4e-26 85.8 In-house 1-214 (277) Show / Hide 
Range on Protein: 185-397
Range on HMM: 1-214/277
Sequence Identity: 30% (70 aa)

FAVSNVIGKGGYGTVYKGELKGTGGIVAVKRLHSGNDTSQNGSRERLRQSLTELRTLARFRHDNILPIYAYSL----EGSEPCLVYQFMSNGSLEDRLLC
 .. . ||||..|.||||  .|.  .|||| | . |...   . ..|   . |   ..  || ||.  . ...    . ...| |  .|. |.|.  |. 
INIEQRIGKGSFGEVYKGTWRGK--EVAVKKLNNHNQNF---DENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHD

----RKGSVPLTWIQRKE---ISIGAGRGLGFLHSFGKTPIIHGDIKTANILLDKHMEPKIGDFGLCR----DGHVEAEAMEKHPLIASHIKGTLAYLAP
     . |..| |. .|    . . | ||.  ||.   . ||| |.|..|.| ||..  |..|||| .    .    . .|          .|| .. ||
KPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQM--------TACGTPCWMAP

EFITSKILTTKLDVYSFGIVLLEIASGQ
|   ..  . | ||||||||| ||. .|
EVMMHQPYNEKADVYSFGIVLWEILTRQ
Kinase pik-1.AA Pkinase_Tyr 185-342 28 2.5e-24 83.04 Pfam 1-160 (270) Show / Hide 
Range on Protein: 185-342
Range on HMM: 1-160/270
Sequence Identity: 28% (48 aa)

FAVSNVIGKGGYGTVYKGELK----GTGGIVAVKRLHSGNDTSQNGSRERLRQSLTELRTLARF-RHDNILPIYAYSL-EGSE--PCLVYQFMSNGSLED
     ..|.| .|.||||..|    .|.  |||| |  | . .||     ..  . |....  . .|.||.  |.  . .|    ...|  .| .|.| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN----CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

RLLCR-KGSVPLTWIQRKEISIGAGRGLGFLHSFGKTPIIHGDIKTANILLDKHMEPKIGDFGLCRD
 |  .  .  |||  .  ....   .|. .|.| .   .|| |. . |.|... .  ||.||||.||
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARD
Kinase pik-1.AA TyrKc 185-476 21 9e-22 79.57 SMART 1-280 (280) Show / Hide 
Range on Protein: 185-476
Range on HMM: 1-280/280
Sequence Identity: 21% (69 aa)

FAVSNVIGKGGYGTVYKGELKGTGGIVAVKRLHSGNDTSQNGSRERLRQSLTELRTLARF--RHDNILPIYAYSLEG-------SEPCLVYQFMSNGSLE
     ..| | .|.||||..|     |||| |...           ..  . |.| . ..  .|.||. .|.. ...         ...|  .|..|.| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

DRLLCRKGSVPLTWIQRKEISIGAGRGLGFLHSFGKTPIIHGDIKTANILLDKHMEPKIGDFGLCRDGHVE-AEAMEKHPLIAS----HIK--GTLAYLA
|.|  ...   |.. .  .... . .|  .|||    ..|| |. . |.|...    ||.||||.||.. . ..  | .  . .    . |    .  .|
DYLRKHRPK--LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTMLPIRWMA

PEFITSKILTTKLDVYSFGIVLLEIASGQRAYSDS-----RETRGLVEYCQVNKELAAHRK----IPVREIFIDRRAPPLVGDEEKS--FLDALIEVGLA
|| |  .. ||| ||.|||... || .              . . ..|| .  . .                              .    |.. .. . 
PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------FVCCPDEMYQIMKQ

GANNDRKVRPTMSQIVEYL
  . | . |||.|.|.|..
CWHEDPEDRPTFSEIHECF
Kinase pik-1.AA Dicty4-Unclassified 301-396 35 4.1e-17 55.14 In-house 120-204 (263) Show / Hide 
Range on Protein: 301-396
Range on HMM: 120-204/263
Sequence Identity: 35% (34 aa)

RGLGFLHSFGKTPIIHGDIKTANILLDKHMEPKIGDFGLCRDGHVEAEAMEKHPLIASHIKGTLAYLAPEFITSKILTTKLDVYSFGIVLLEIASG
.|. .||.     .|| ||| .|||.|||   ||.|||. |      .      . .  | || .  .||       . | ||||....| | | |
QGMQHLHTRN---FIHRDIKSSNILMDKHFNIKIADFGISR------VIDFNFNMTT--IAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATG
Kinase pik-1.AA Dicty4-Unclassified 185-274 29 5.8e-07 19.85 In-house 1-89 (263) Show / Hide 
Range on Protein: 185-274
Range on HMM: 1-89/263
Sequence Identity: 29% (28 aa)

FAVSNVIGKGGYGTVYKGELKGTGGIVAVKRLHSGNDTSQNGSR-ERLRQSLTELRTLARFRHDNILPIYAYSLEG----SEPCLVYQFMSNGSL
  .   ||||    |.||  ||    |||| . .. .      | | .   . |   |    | | . .| |..      |  | |  ||  | |
IQIDQFIGKGHFSKVHKGNWKGKD--VAVKKFNENKFK----FREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNL
Kinase pik-1.AA Dicty4-Unclassified 461-476 62 0.000761 9.01 In-house 248-263 (263) Show / Hide 
Range on Protein: 461-476
Range on HMM: 248-263/263
Sequence Identity: 62% (10 aa)

NDRKVRPTMSQIVEYL
|| . |||| ||..||
NDPNKRPTMNQIIQYL
Kinase pik-1.AA MLK 466-476 54 0.001895 7.98 In-house 281-291 (291) Show / Hide 
Range on Protein: 466-476
Range on HMM: 281-291/291
Sequence Identity: 54% (6 aa)

RPTMSQIVEYL
||...|||..|
RPSFRQIVQHL
Kinase pik-1.AA TK 462-476 53 0.004182 5.4 In-house 472-486 (486) Show / Hide 
Range on Protein: 462-476
Range on HMM: 472-486/486
Sequence Identity: 53% (8 aa)

DRKVRPTMSQIVEYL
| . |||.||..|.|
DPEDRPTFSQLHEQL
Kinase pik-1.AA Pkinase_Tyr 367-395 48 0.005023 10.87 Pfam 181-209 (270) Show / Hide 
Range on Protein: 367-395
Range on HMM: 181-209/270
Sequence Identity: 48% (14 aa)

LAPEFITSKILTTKLDVYSFGIVLLEIAS
.||| |  .. ||| ||.|||... || .
MAPECINYGKFTTKSDVWSFGVLMWEIFT
Kinase pik-1.AA Dicty4 464-478 23 0.03217 3.4 In-house 261-277 (277) Show / Hide 
Range on Protein: 464-478
Range on HMM: 261-277/277
Sequence Identity: 23% (4 aa)

KVRPTMSQIVEY--LCK
..||....|...  |  
QHRPSFEEIIQRRILEH
Kinase pik-1.AA LRRK 466-478 53 0.081755 2.18 In-house 339-351 (351) Show / Hide 
Range on Protein: 466-478
Range on HMM: 339-351/351
Sequence Identity: 53% (7 aa)

RPTMSQIVEYLCK
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RPHFSQIVKRLSQ
Kinase pik-1.AA TKL-Unique 466-476 36 0.103046 2.04 In-house 280-290 (290) Show / Hide 
Range on Protein: 466-476
Range on HMM: 280-290/290
Sequence Identity: 36% (4 aa)

RPTMSQIVEYL
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RPSFDEIIHRL
Kinase pik-1.AA Pkinase_Tyr 466-476 63 0.123511 6.16 Pfam 260-270 (270) Show / Hide 
Range on Protein: 466-476
Range on HMM: 260-270/270
Sequence Identity: 63% (7 aa)

RPTMSQIVEYL
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RPTFSEIHEQL