Gene pkc-3 (Nematode worm)

pkc-3

Species: Nematode worm
Alias: CE02604, aSWK017, F09E5.1, pkc-3
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: II: 5379992-5384138, WormBase Genetic Map location: II:-1.57,

Classification

Group: AGC
Family: PKC
Subfamily: PKCi

Sequence

Name Sequence Type Origin Length Description Download
pkc-3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 270 Kinase domain by global Sugen HMM Fasta, JSON
pkc-3.AA Protein Genbank 597 None Fasta, JSON

Protein domain

Protein domains of pkc-3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PB1 pkc-3.AA PB1 12-95 23 1.5e-23 86.17 Pfam 1-86 (86) Show / Hide 
Range on Protein: 12-95
Range on HMM: 1-86/86
Sequence Identity: 23% (21 aa)

DIKLKTRFQGQVVV--LYARPPLILDDFFALLKDACKQHKKQDITVKWIDEDG-DPISIDSQMELDEAVRCLNSS-QEAELNIHVFVG
....| |..| ..   .. |... ..|....... ||..  .... ...|||| | ..| ....|.|.... .|| . ..|..|||..
TVRIKCRYGGDIRRFIIHVRRNISFEDLMHKVEQRCKCD--HTFKYQYPDEDGDDWVTITCDEDLQEMMEEYRSSEKSMTLRLHVFPS
PB1 pkc-3.AA PB1 12-95 24 2.2e-23 84.92 SMART 1-95 (95) Show / Hide 
Range on Protein: 12-95
Range on HMM: 1-95/95
Sequence Identity: 24% (23 aa)

DIKLKTRF-QGQVVVLYARPPLILDDFFALLKDACKQHKKQDITVKWI--DEDGD-PISIDSQMELDEAVRCLNS-------SQEAELNIHVFVG
....| |.  |.....  .... .||. ..... |.... |..|.|..  ||||| ...| ....|.|......|       |. . |..|||. 
PVDVKCRYVGGDTRRFSVPRDWSFDDLMSKVAQRCGHDNDQPFTLKYQLPDEDGDAWVTITCDEDLQEMMEMYDSLESQNKSSCWKTLRLHVFPF
C1_1 pkc-3.AA C1_1 128-180 29 4.8e-12 47.86 Pfam 1-55 (55) Show / Hide 
Range on Protein: 128-180
Range on HMM: 1-55/55
Sequence Identity: 29% (16 aa)

HRFQAK-RLNRRIQCFICHDYIWG-IGRQGFRCVDCRLCVHKKCHRHVRTHCGQA
|..... ....   |  | . .|| .|.||..| .| ...|..||..| . ||  
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN
C1 pkc-3.AA C1 128-177 30 2e-10 41.91 SMART 1-61 (61) Show / Hide 
Range on Protein: 128-177
Range on HMM: 1-61/61
Sequence Identity: 30% (19 aa)

HRFQAKRLNRRIQCFICHDYIWGIGRQ-----GFRCVDCRLCVHKKCHRHVRT-------HC
|.....|  ..  | .|...|||. .|     |.|| .|.. .|||||..|          |
HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
Kinase pkc-3.AA Iota 253-522 81 2.1e-223 748.48 In-house 1-271 (271) Show / Hide 
Range on Protein: 253-522
Range on HMM: 1-271/271
Sequence Identity: 81% (222 aa)

FRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEAASNYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEE
|.|..||||||||||...||..||.|||.|.|||||.|.|||||||||||.|||.|||.|||||||||||||||||||||||.|||||||||.|||||||
FELIRVIGRGSYAKVLMVEHKKTRRIYAMKVIKKEMVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEFVNGGDLMFHMQRQRKLPEE

HARFYSGEIILALHFLHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPEILRGDEYGFSVDWWALGVLMFEMMAGRSPF
||||||.||.|||.|||.||||||||||||||.|.||||||||||||||.|..||.||||||||||||||||||..||||||||||||||||||||||||
HARFYSAEICLALNFLHERGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPF

DIVG-MQNSEENTEDYLFQIILERQIRIPRSLSVRASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFF
|||| |.|...||||||||.|||.||||||||||||...|||||||||.|||||....|||..|.|||.||
DIVGNMDNPDQNTEDYLFQVILEKQIRIPRSLSVRAAHVLKGFLNKDPKERLGCHPQTNEGFMDIKEHPFF
Kinase pkc-3.AA PKC 253-522 58 7.4e-197 643.84 In-house 1-262 (262) Show / Hide 
Range on Protein: 253-522
Range on HMM: 1-262/262
Sequence Identity: 58% (158 aa)

FRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEAASNYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEE
|..|.|.|.||..||. ||.  |...||||..||.....|.|.....||| |.. |...|||..||.||||..|||||.|.| |||||||.||||...||
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

HARFYSGEIILALHFLHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPEILRGDEYGFSVDWWALGVLMFEMMAGRSPF
|||||. |||.||.|||..|||||||||||||.|.|||||..|.||||||. .|| ||||||||.|||||||...|||.||||||.||||.|||||.|||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

DIVGMQNSEENTEDYLFQIILERQIRIPRSLSVRASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFF
...        .||.|||.|.......||.||..|..|.|||..|.|..||||. . .|| .|..||.||
HGE--------DEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase pkc-3.AA AGC 253-522 30 3.6e-174 454.83 In-house 1-395 (395) Show / Hide 
Range on Protein: 253-522
Range on HMM: 1-395/395
Sequence Identity: 30% (121 aa)

FRLLTVIGRGSYAKVVQAEHV------STRQIYAIKIIKKEM-FNEDE--DIDWVQTE------------KSVFEAASN---------YPFLVG-LHSCF
|..|.|||.||. || .....      .| ..||.|..||.    ...  ... ..||            . ..| ...          ||.|  ||..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTESR--LFFVIEFVP---------GG-DLMFHMQ---QQRKLPEEHARFYSGE-------IILALHFLHS-RGIIYRD-LKLDNVLIDAEGHIKLTDYG
|....  |.|| |..|         || .|..|.|   ......||.||||  |       |.|||..||| .|||.|| ||..|.|.|..||||||| |
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

MCKENIKDG--------------------------------------------------DLTSTFCG--TPNYIAPEILRGDEYGFSVDWWA--LGVLMF
.|||...||                                                  |.|.||||  ||.|.|||||    ||...|||.  ||.||.
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMMAGRSPFDIVGMQ---NSEENTEDYLFQIIL------ERQIRIP----------RSLSVRASGILKGFLNKDPTERLGCKLDINE--GLRDMKEHQFF
||..|..||     |     . .... .|| |.      . ....|          |..|. |  ..|..|.|||..||||. . ..  |  . |.| .|
EMLTGYPPFYGDNPQENRH-PFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase pkc-3.AA Alpha 253-522 53 2.7e-124 419.25 In-house 1-259 (259) Show / Hide 
Range on Protein: 253-522
Range on HMM: 1-259/259
Sequence Identity: 53% (145 aa)

FRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEAASNYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEE
|  |.|.|.||. ||  ||   |   ||||| ||     | |..   .|| |    .  |||| .||||||  ||.|| |.| |||||.|.||  |  | 
FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQDDDVECTMVEKRVLALPGKPPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFKEP

HARFYSGEIILALHFLHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPEILRGDEYGFSVDWWALGVLMFEMMAGRSPF
|| ||  ||  .| |||..||||||||||||..|||||||..|.||||||. ... | ||||||.||||||   . || |||||| |||..|||||  ||
HAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQPPF

DIVGMQNSEENTEDYLFQIILERQIRIPRSLSVRASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFF
|         . || ||| | |..   |.|.|. |  | |||| | |  ||||  |     .| .||.||
D--------GEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKRLGCGPDGE---QDIREHPFF
Kinase pkc-3.AA Eta 253-522 51 2.2e-123 416.23 In-house 1-261 (261) Show / Hide 
Range on Protein: 253-522
Range on HMM: 1-261/261
Sequence Identity: 51% (140 aa)

FRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEAASNYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEE
|  . |.|.||. ||. ||.  | ..||||..||..   |.|..   ||| .   | . |||  ||.||||. |||||.|.| ||||||..|. ||  | 
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFDEP

HARFYSGEIILALHFLHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPEILRGDEYGFSVDWWALGVLMFEMMAGRSPF
 ||||  |...|| ||| .|.|||||||||.|.|.||| || |.||||| | .| .|.|||||| |||||||.  ||| ||||||.||||.|||.|..||
RARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPPF

DIVGMQNSEENTEDYLFQIILERQIRIPRSLSVRASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFF
        | . || ||. ||. ..  |  |.  | .|||.|. | |..|||| .    | .....| ||
--------EADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGC-MTAQGGEHAIRQHPFF
Kinase pkc-3.AA Akt 253-522 41 2e-119 383.48 In-house 1-264 (264) Show / Hide 
Range on Protein: 253-522
Range on HMM: 1-264/264
Sequence Identity: 41% (115 aa)

FRLLTVIGRGSYAKVVQAEHVSTRQIY-AIKIIKKEMFNEDEDIDWVQTEKSVFEAASNYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPE
|..| |.|.||..||....  .| ..| |.|..||..  .   .  ..||. . .     ||.|.||  |||. .|.|| ....||.| .|.|..|. .|
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCN-HPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE

EHARFYSGEIILALHFLHSRGIIYRD-LKLDNVLIDAEGHIKLTDYGMCKEN-IKDGDLTSTFCGTPNYIAPEILRGDEYGFSVDWWA-LGVLMFEMMAG
. ||||  |||||. .|||..||||| ||. |.|.|..|||.||| |.|||| |||.| | |||||| |.||||| |  .. .||||. ||..|.||| |
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG

RSPFDIVGMQNSEENTEDYLFQIILERQIRIP--RSLSVRASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFF
| ||        ... .  .|. |.. ....|  . .|  .  ...| |||||..||| .   ...... |.| .|
RPPF-------YNQDHHQ-MFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGG---PNDAQEIKRHPWF
Kinase pkc-3.AA SGK 253-522 37 2.9e-117 363.8 In-house 1-283 (283) Show / Hide 
Range on Protein: 253-522
Range on HMM: 1-283/283
Sequence Identity: 37% (111 aa)

FRLLTVIGRGSYAKVVQAEHVST------------------RQIYAIKIIKKEMFN-------EDEDIDWVQTEKSVFEAASNYPFLVGLHSCFQTESRL
|..|.||| ||. || |..|...                   ..||.|...|.            .    ...|..|     . ||.|.||  |||.  |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FFVIEFVPGGDLMFHMQQQRKLPEEHARFYSGEIILALHFLHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPEILRGD
.|| ..| ||.. .|.|  ...||  ||||  ||..||  |||  ||||||| .|.| |..||..||| | |||.||. | |.|||||| | |||.||. 
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

EYGFSVDWWALGVLMFEMMAGRSPFDIVGMQNSEENTEDYLFQIILERQIRIPRSLSVRASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFF
... .|||| || ...||| |  ||        . .    ... |.   ..||.. |. |. ...| |.|||..||| |    .. .. |.|.||
PHDRTVDWWCLGCVLYEMMYGLPPF--------YSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK----RDFMEIKNHPFF
Kinase pkc-3.AA Delta 253-522 47 8.10000000001e-107 361.18 In-house 1-259 (259) Show / Hide 
Range on Protein: 253-522
Range on HMM: 1-259/259
Sequence Identity: 47% (128 aa)

FRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEAASNYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEE
| .. |.|.||. ||. ||   ... |||| .||..  ||.|..    |. |   |.. |||  |   |||.. ||||.|.. |||||.|.||...  |.
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEK

HARFYSGEIILALHFLHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPEILRGDEYGFSVDWWALGVLMFEMMAGRSPF
 ||||. |||..|.|||..|||||||||||||.| .||||. |.||||||.     .||||||| ||||||..|. | .|||||. ||||.||. | |||
RARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPF

DIVGMQNSEENTEDYLFQIILERQIRIPRSLSVRASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFF
        . . || ||. |.. .   || ..  | ..||. ...||..||| . .  .|  |...|.||
--------HGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQ-YCPKG--DIRQHCFF
Kinase pkc-3.AA AktR 253-522 35 1.4e-95 323.87 In-house 1-268 (268) Show / Hide 
Range on Protein: 253-522
Range on HMM: 1-268/268
Sequence Identity: 35% (99 aa)

FRLLTVIGRGSYAKVVQAEHV-STRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEAASNYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPE
|... ..|.| ..||. ...   . ..||.|.|||. . | . .. ..||. . |. .| ||.| || ||||.. |||..|..|||.| .| ....|. |
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

EHARFYSGEIILALHFLHSR-GIIYRDLKLDNVLIDAEGHIKLTDYGMCK-ENIK-DGDLTSTFCGTPNYIAPEILRG-DEYGFSVDWWALGVLMFEMMA
| ||||. .|.||| .||..  ||||||| .| |.| .||.|.||.|. | .... . ... .||||| |.|||...  . ...||||||.|.. .||..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GRSPFDIVGMQNSEENTEDYLFQIILERQIRIPRS--LSVRASGILK-GFLNKDPTERLGCKLDINEGLRDMKEHQFF
|  ||      ... .........| . |...| .  .|  .  ... . |.|.|..|||    ...|  . |.| .|
GCPPF------YHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGY---YCNGWEEIKSHPWF
Kinase pkc-3.AA PKN 253-522 42 2.3e-91 309.83 In-house 1-260 (260) Show / Hide 
Range on Protein: 253-522
Range on HMM: 1-260/260
Sequence Identity: 42% (116 aa)

FRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEAASN--YPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLP
||...|.||| . ||. ... .| ..||||..||.     .... . .|| .||...    |||| |..|||||.  .||.|...||||| |. .    .
FRCIAVLGRGHFGKVLLSQYKHTGEYYAIKALKKQDIVARDEVESLMCEKRIFEVVNRMRHPFLVNLFACFQTEEHVCFVMEYAMGGDLMMHIHEDV-FS

EEHARFYSGEIILALHFLHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPEILRGDEYGFSVDWWALGVLMFEMMAGRS
| .|.||.  ..| | .|| . ||||||||||.|.|.||..|. |.|.|||..  || |||||||| ..|||.|  . |   |||| ||||..||. | .
EPRACFYAACVVLGLQYLHEHKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGEC

PFDIVGMQNSEENTEDYLFQIILERQIRIPRSLSVRASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFF
||           .|. .|. |.. ..| || ||| |  |..  | | |  |||      |   |.| ..||
PF--------PGDDEEEVFDCIVNDDVRYPRFLSVEAIAIMRRLLRKNPERRLGAGERDAE---DIKMQPFF
Kinase pkc-3.AA S_TKc 253-522 32 6.9e-90 305.85 SMART 1-231 (231) Show / Hide 
Range on Protein: 253-522
Range on HMM: 1-231/231
Sequence Identity: 32% (90 aa)

FRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEAASNYPFLVGLHSCFQTESRLFFVIEFVPG--GDLMFHMQQQRK--
...| .||.|...|| .. |..| .|.||||||          . .. | .. .   . |..| |. .||. ..|..| |...|  |||. .......  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LPEEHARFYSGEIILALHFLHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPEILRGDEYGF-SVDWWALGVLMF
    .|| |||||  .|..|| ..||.|||.|||| .|.|.|   |||..| |....        .||||||.|.|||.|    ||. ..|||..|....
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EMMAGRSPFDIVGMQNSEENTEDYLFQIILERQIRIPRSLSVRASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFF
||..|. ||.          ... .|..|.          |  |  .... |.|||..|...    .... | | |..|
EMLCGYPPFP----------QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEW-DIKCHPWF
Kinase pkc-3.AA Pkinase 253-522 27 5.8e-78 270.12 Pfam 1-293 (293) Show / Hide 
Range on Protein: 253-522
Range on HMM: 1-293/293
Sequence Identity: 27% (85 aa)

FRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQ-TEKSVFEAASNYPFLVGLHSCFQTESRLFFVIEFVPGG----DLMFHMQ--Q
.... .||.||...| .. |..|..|.|.|||||.  ....|.  .  .| ..     | |. | |. .|...... .| |...||    ||. ...  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

QRKL--PEEHARFYSGEIILALHFLHSRGIIYRDLKLDNVLIDAEGHI----KLTDYGMCKE--NIKDGDLTSTFCGTPNYIAPEILR-GDEYGFSVDWW
....  .|....||  .|. .| ..||.|||.||||..|.||| .|||    |..| | .|   . ...  ..||||||.|.|||..| | .|| .||.|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

ALGVLMFEMMAGRSPFDIVGMQNSEENTEDYLFQIILERQIRIPRSLS---------------------VRASGILKGFLNKDPTERLGCKLDINEGLRD
..|....||. || ||.  . .  . ........ |...... ... .                       .  ..|. |.|||..|..         ..
SCGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT--------AEQ

MKEHQFF
 ..| .|
ILQHPWF
Kinase pkc-3.AA TyrKc 253-513 18 8.2e-13 -15.54 SMART 1-280 (280) Show / Hide 
Range on Protein: 253-513
Range on HMM: 1-280/280
Sequence Identity: 18% (54 aa)

FRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEAA-SNYPFLVGLHSCFQTE-------SRLFFVIEFVPGGDLMFHMQ
 .|. ..|.| . .|....     .  |.| .|..       .     | ..      . | .| |. .  ..         |. | |..|.|||  . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QQRK-LPEEHARFYSGEIILALHFLHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKD-------GDLTSTF--CGTP----NYIAPEILRGDEYG
  |. |. ..   ..  |     .|||...| |||   |.|.......| .| |....   |          ...   .|         ||| ..  .. 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

FSVDWWALGVLMFEMMA-GRSPFDIVGMQNSEENTEDYLFQIILERQIRIPRSL----------SVRASGILKGFLNKDPTERLGCKLDINEGL
.  | |. ||.|.|..  | .|   .  |     . . ... . ..  . .             .   . | |   . || .|  .  .| | .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQ---MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRP-TFSEIHECF
Kinase pkc-3.AA Pkinase_Tyr 253-461 22 2.5e-09 32.21 Pfam 1-223 (270) Show / Hide 
Range on Protein: 253-461
Range on HMM: 1-223/270
Sequence Identity: 22% (50 aa)

FRLLTVIGRGSYAKVVQAEHV----STRQIYAIKIIKKEMFNEDE--DIDWVQTEKSVFEAASNYPFLVGLHSCFQ-TESR--LFFVIEFVPGGDLMFHM
 ... ..|.|.. .|....      .|..  |.|.. ||   ...    |  . | ..     . | .| |. .    .    .. | |..|.|||  . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

QQ----QRKLPEEHARFYSGEIILALHFLHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDL-TSTFCGT--PNYIAPEILRGDEYGFSVDWW
..    ...|. ..   .. .|  .. .|.|...| |||   |.|.. ....| .| |...   .|.   ...  |       ||| ..  ..    | |
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

ALGVLMFEMMA-GRSPFDIVGMQNSE
. ||||.|..  |..| .  || |.|
SFGVLMWEIFTYGEQP-TYPGMSNEE
S_TK_X pkc-3.AA S_TK_X 524-587 34 6.8e-20 73.34 SMART 1-79 (79) Show / Hide 
Range on Protein: 524-587
Range on HMM: 1-79/79
Sequence Identity: 34% (27 aa)

GFIDWEALEQ--KAVAPPYHPAVE----SDRDLTHFDHQFTDELPQLSPDNPDVIARIDQSE---------FDGFEYVN
  |||..|..  | . ||. | .     |..|.  ||  ||.| | |.||.| ......|.|         | || ||.
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Pkinase_C pkc-3.AA Pkinase_C 543-589 42 6.3e-15 55.76 Pfam 1-46 (46) Show / Hide 
Range on Protein: 543-589
Range on HMM: 1-46/46
Sequence Identity: 42% (20 aa)

AVESDRDLTHFDHQFTDELPQLSPDNPDVIARIDQSEFDGFEYVNPL
 |.|..|  .||..|||| |...|. .. .  .||..| || |||| 
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD