Gene prk-2 (Nematode worm)

prk-2

Species: Nematode worm
Alias: prk-2, aSWK063, CE31517, F45H7.4
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: III: 3365739-3359211, WormBase Genetic Map location: n/a,

Classification

Group: CAMK
Family: PIM

Sequence

Name Sequence Type Origin Length Description Download
prk-2.AA Protein Genbank 363 None Fasta, JSON
prk-2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 255 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of prk-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase prk-2.AA PIM 31-285 60 6.9e-202 676.99 In-house 1-260 (260) Show / Hide 
Range on Protein: 31-285
Range on HMM: 1-260/260
Sequence Identity: 60% (156 aa)

YKLKAELGRGGFGVVYRAVRTCDN-ALVAVKFIERSNVKEWARIN-GEQVPMEICMLAKCSKV---RGVIRLLDWYSIPEGFLIVMERPYPCIDMFDFIK
|....||||||||.||...|.||| ..||.|..|...||.|.... |.|||||.|||.|||..   .||||||||...|.||.|||||||||.|.||||.
YQVGPELGRGGFGTVYAGHRICDNQQPVAIKHVEKERVKDWGMLCDGQQVPMEVCMLWKCSSIGGHHGVIRLLDWFERPDGFMIVMERPYPCQDLFDFIT

GQGKISEDMARFLFRQIAVTVHECVQNRVLHRDLKDENIVIDLVTGSTKLIDFGAATVLRRSQYSDFQGTRLYCPPEWFLHSLYLGREAAVWSLGVLLYN
.||...|||.||.|.|...|||.|.|..|||||.|||||.||..||..|||||||...|....|.||.|||.||||||..|..|.||||.|||||||||.
EQGPLNEDMCRFFFWQVWATVHHCHQCHVLHRDIKDENILIDMNTGEVKLIDFGAGAMLHDTVYTDFDGTRVYCPPEWIRHHRYHGREATVWSLGVLLYD

SLNGRLPFRNEKDICTAHLLGPLPFFVPVSAEVKDLISKCLTFDPFQRCSLEAILNHPWV
...|..||.|...||.|||||.|.|...||.|...||..||||.|..|||||.||||||.
MVCGDIPFENDQEICRAHLLGELHFRQHVSHECCQLIRWCLTFKPSHRCSLEQILNHPWM
Kinase prk-2.AA CAMK 36-285 21 8.9e-84 269.71 In-house 1-425 (425) Show / Hide 
Range on Protein: 36-285
Range on HMM: 1-425/425
Sequence Identity: 21% (93 aa)

ELGRGGFGVVYRAVRTCDN------------ALVAVKFIERSNVKE----------------------WARINGEQ-VPMEICMLAKCSK------VRGV
.||||.||.|...... ..              ||.|.|... .|.                      | | . .. |. ||... |...       . .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLLDWYS--------IPEG------------FLIVM---ERPYPC---IDMFDFIKGQ---------------GKISEDMARFLFRQIAVTVHECVQNR
|.|...|         .. .            . .||   |        .|.||.|. .               |...|. ||..||||.  || | .. 
IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VLHRDLKDENIVIDLVT----------------GSTKLIDFGAATVLRRSQ-------------------------YSDFQGTRLYCP-PEWFLH-----
. ||||| ||| .|                   .  |.|||| |.......                         ...| ||  |.. ||...      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------SLYLGREAAVWSLGVLLYNSLNGRLPFRNE---------------KDICTAHLLGPLPFFVP------------------------VSAEVK
          | |... .||.||.||  | |..||. .               ....   . |   |  |                        ||.|.|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLISKCLTFDPFQRCSLEAILNHPWV
|||.|.|. || .| ..| .|||||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase prk-2.AA Pkinase 31-285 29 1.3e-64 225.72 Pfam 1-293 (293) Show / Hide 
Range on Protein: 31-285
Range on HMM: 1-293/293
Sequence Identity: 29% (90 aa)

YKLKAELGRGGFGVVYRAVRTCDNALVAVKFIERSNVKEWAR-----INGEQVPMEICMLAKCSKVRGVIRLLDWYSIPEGFLIVMERP----YPCIDMF
|...  .|.|.||.||....  .. .|||| |.... |.| .     .      .||...... .   ..||.||.  .    .|||      | ..| |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL------SEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLF

DFIK--GQGKI--SEDMARFLFRQIAVTVHECVQNRVLHRDLKDENIVIDLVTGST----KLIDFGAAT---VLRRSQYSDFQGTRLYCPPEWFLHSLYL
|.|.   .|..  ||. ..| ..||.  .  | .....||||| ||| ||  .| .    |..||| |      . | ...| ||. |..||. ... | 
DYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYY

GREAAVWSLGVLLYNSLNGRLPFRNE-------KDICTAHLLG-PLPFFVPVS---------------------AEVKDLISKCLTFDPFQRCSLEAILN
|... .||.|..||  |.||.||...       .. . .  .| ||.|  | .                      | ||.|..||..|| .|.. | ||.
GPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ

HPWV
|||.
HPWF
Kinase prk-2.AA S_TKc 31-285 29 4e-61 210.31 SMART 1-231 (231) Show / Hide 
Range on Protein: 31-285
Range on HMM: 1-231/231
Sequence Identity: 29% (81 aa)

YKLKAELGRGGFGVVYRAVRTCDNALVAVKFIERSNVKEWARINGEQVPMEICMLAKCSKVRGVIRLLDWYSIPEGFLIVMERPYPC--IDMFDFIKGQG
|..  ..|.|.||.||... . .. .||.| |             |..  || .| |  .   ...|.|..   . . .|||   .    |.||.|| .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEY-CDGDLGDLFDYIKKRG

K------ISEDMARFLFRQIAVTVHECVQNRVLHRDLKDENIVIDLVTGSTKLIDFGAATVLRRSQYSDFQGTRLYCPPEWFLHSLYLGR-EAAVWSLGV
.      ..| .|||...||.  .  | .....||||| ||| .|      |..||| |..|     . | ||. |..|| .      |. .. .||.|.
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGC

LLYNSLNGRLPFRNEKDICTAHLLGPLPFFVPVSAEVKDLISKCLTFDPFQRCSLEAILN-------HPWV
.||  | |. ||.   .  . ...|        | |.||.|.|||..|| .| .   .|.       |||.
ILYEMLCGYPPFP--QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase prk-2.AA CAMKL 31-285 28 1.1e-53 169.66 In-house 1-297 (297) Show / Hide 
Range on Protein: 31-285
Range on HMM: 1-297/297
Sequence Identity: 28% (86 aa)

YKLKAELGRGGFGVVYRAVRTCD-NALVAVKFIE--RSNVKEWARINGEQ--------VPMEICMLAKCSKVRG---VIRLLDWYSIPEG------FLIV
|..  .||.|.||.|  |. .   .  ||.|.|.  . . ..|.. |           .  ||. . . . ...   .|.|.. .  ||       . .|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN-IGKHPNIIKLYEVIETPEHDIETKKIYLV

MERPYPC---IDMFDFI--KGQ--GKISEDMARFLFRQIAVTVHECVQNRVLHRDLKDENIVIDLVTGS-TKLIDFGAATVLR------RSQYSDFQGTR
||  | .   .|.||.|  .|   |...|. ||..||||   |. | .... |||.| ||| .|    .  |.|||| ..  |          . | |. 
ME--YCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP

LYCPPEWFLH--SLYLGREAAVWSLGVLLYNSLNGRLPFRNEK-----------DICTAHLLGPLPFFVPVSAEVKDLISKCLTFDPFQRCSLEAILNHP
 |..|| |.     | |... .||.||.||. . |.|||...               .  . .  | .. || ...|||.| |. .| .| ... |.|||
PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

WV
|.
WM
Kinase prk-2.AA PASK 31-285 30 1e-49 153.34 In-house 1-260 (260) Show / Hide 
Range on Protein: 31-285
Range on HMM: 1-260/260
Sequence Identity: 30% (81 aa)

YKLKAELGRGGFGVVYRAVRTCDNALVAVKFIERSNVKEWARING---EQVPMEICMLAKCS--KVRGVIRLLDWYSIPEGFLIVMERPYPC--IDMFDF
|    ..|.| .| |. ...  .. .| |||| .  | |   .      ..|.|| ....        ....|| .   . . .|||       .| |||
YTSIQQMGEGAYGYVWMCIHNECRYIVVVKFIFKEKVCEDCWVRDRKCGCIPLEIHIMQTLNKNPHENIVKVLDFFENDDFYQLVMEKHGSGGCMDLFDF

IKGQGKISEDMARFLFRQIAVTVHECVQNRVLHRDLKDENIVIDLVTGSTKLIDFGAATVLRRSQ-YSDFQGTRLYCPPEWFLHSLYLGREAAVWSLGVL
|  . .. |  | . |||..  |    .  ..||| ||||..||   .  |||||| |. ..|   .. | ||  || ||  . . | |.|  .|.|||.
IDRHPNMDEHLASYIFRQVVAAVKYLHEQGIVHRDIKDENVIID-EHFTIKLIDFGSAAYMERGKFFYTFCGTIEYCAPEVLMGNPYRGPEQEMWALGVT

LYNSLNGRLPFRNEKDICTAHLLGPLPFFVPVSAEVKDLISKCLTFDPFQRCSLEAILNHPWV
||  .    || |   .  | .   .|    || |.  ||.  |. .| .|| .. | . ||.
LYTLMFKENPFCNIEETLEAEIH--FPNAEHVSEECMSLIKSMLNRCPEKRCTMHQIITDPWL
Kinase prk-2.AA MARK 119-285 37 2.5e-38 122.98 In-house 88-262 (262) Show / Hide 
Range on Protein: 119-285
Range on HMM: 88-262/262
Sequence Identity: 37% (65 aa)

DMFDFIKGQ--GKISEDMARFLFRQIAVTVHECVQNRVLHRDLKDENIVIDLVT-GSTKLIDFGAATVLRRSQ-YSDFQGTRLYCPPEWFLHSLYLGREA
...|.|| .  |...|. || .||||   |. | .... |||.| ||| ||  .    |.|||| ..     |  . | ||  |..|| ||   | |...
ELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKV

AVWSLGVLLYNSLNGRLPFR--N--EKDICTAHLLGPLPFFVPVSAEVKDLISKCLTFDPFQRCSLEAILNHPWV
 .|||||.||  . |..||.  .  .|..    | |  ...  ||.| ..||.. ||..| .| ..| |..|||.
DIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase prk-2.AA SNRK 31-285 34 1.3e-34 110.6 In-house 1-254 (254) Show / Hide 
Range on Protein: 31-285
Range on HMM: 1-254/254
Sequence Identity: 34% (89 aa)

YKLKAELGRGGFGVVYRAVRTCDNALVAVKFIERSNVKEWARINGEQVPMEI-CMLAKCSKVRGVIRLLDWYSIPEGFLIVMERPYPCIDMFDFI-KGQG
| |   |||| | ||  |      . |||| |..  . | ..    ..  |. ||  |  .   ..|| .         ...|      ||.|.| | . 
YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKMDEVSK---AHLFQEVRCM--KLVQHPNIVRLYEVIDTQTKLYLILELGD-GYDMYDYIMKHEK

KISEDMARFLFRQIAVTVHECVQNRVLHRDLKDENIVIDLVTGSTKLIDFG-AATVLRRSQYSDFQGTRLYCPPEWFLHSLYLGREAAVWSLGVLLYNSL
 ..||.||  |.||   .  | | .| ||||| ||.|     |  || ||| .       .   . |   |  ||  |   |      .|||||.||  .
GLCEDLARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLV

NGRLPFRNEKDICTAHLLGPLPFFVP--VSAEVKDLISKCLTFDPFQRCSLEAILNHPWV
 |..||..  |  |   .    . ||  ||.| .||| . |  || .| ||| | .|.||
CGQAPFQEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV
Kinase prk-2.AA MELK 31-285 32 4.3e-32 106.76 In-house 1-254 (254) Show / Hide 
Range on Protein: 31-285
Range on HMM: 1-254/254
Sequence Identity: 32% (84 aa)

YKLKAELGRGGFGVVYRAVRTCDNALVAVKFIERSNV-KEWARINGEQVPMEICMLAKCSKVRGVIRLLDWYSIPEGFLIVMERPYPCIDMFDFIKGQGK
|..  |.| |||. |  |.    |  ||.| ... .. ..  |..      |.  | . .  . . .|       . ...|||   |  .|||.|  | .
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGHDLPRVK-----TEMDALKNLRHQH-ICQLYHYIETEDKIFMVMEY-CPGGEMFDYIIRQDR

ISEDMARFLFRQIAVTVHECVQNRVLHRDLKDENIVIDLVTGSTKLIDFG-AATVLRRSQYSDFQ---GTRLYCPPEWFLHSLYLGREAAVWSLGVLLYN
..|. .| .||||   .         ||||| ||...|      ||||||  |    |  | . |   |   |  ||      |.| || |||.|.||| 
LEEEETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDH-HLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYV

SLNGRLPFRNEKDICTAHLLGPLPFFVP--VSAEVKDLISKCLTFDPFQRCSLEAILNHPWV
 . | |||  .      . .    . .|  .| | |.|. . |  || .| |.  .||||||
LMCGFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase prk-2.AA Ciliate-E2-Unclassified 31-285 22 2.6e-31 105.86 In-house 1-352 (352) Show / Hide 
Range on Protein: 31-285
Range on HMM: 1-352/352
Sequence Identity: 22% (78 aa)

YKLKAELGRGGFGVVYRAVRTCDNALVAVKFIERSNVKEWARINGEQVPMEICMLAKCSK----VR----------------GVIRLLDWYSIPEGFLIV
||.   .|.||||.||....  .. . | | .  ....    |. ..  .  .|.. ..|    .|                 .......    . . ||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MERPYPCIDMFDFIKGQGK-----------------ISEDMAR-----FLFRQIAVTVHECVQN-RVLHRDLKDENIVIDLVTG--STKLIDFGAAT---
||   .  |....|| ..|                 ..|  |.     |.|.|| .    . ..  ..|||.| |||..|   .    |.|||| .    
MEYC-EGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

--------------VLRRSQYSDFQGTRLYC----PPEWFLHSLYLGR---EAAVWSLGVLLYNSLNGRLPFR--NEKD----------------ICTAH
              ....  ...| ||  |     .|| .    | ..   .. .|||||.||  | |..||   |...                .    
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

LLGPLPFFV--------PVSAEVKDLIS----KCLTFDPFQRCSLEAILNHPWV
. ... |.          .| |.||.|.    |.|  .| .| ..| |||||| 
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase prk-2.AA Ciliate-E2 119-285 22 9.5e-30 99.28 In-house 120-365 (365) Show / Hide 
Range on Protein: 119-285
Range on HMM: 120-365/365
Sequence Identity: 22% (58 aa)

DMFDFIK------------GQGKISEDMARFLFRQIAV---------------TVHECVQNR-VLHRDLKDENIVIDLVTGSTKLIDFGAAT--------
|.||.||            . ....|  ......||.                 .... ..  ..|||.| |||..       |.|||| ..        
DLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------IKIIDFGLSKKYDDDNQN

-------------------------VLRRSQYSDFQGTRLYCPPEWFLHSLYLG--------REAAVWSLGVLLYNSLNGRLPFRNEKDICTAHLLGPLP
                         ..   ..  . ||  | .|| .    | .         .. .|||||.||  | |..||  .. |.   .  | |
RTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--QQQIKQCKIDFPCP

F--------------FVPVSAEVKDLISK----CLTFDPFQRCS-LEAILNHPWV
.              .  .| |.||||.|    .|  || .| .  | |||||| 
EWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase prk-2.AA QIK 119-285 30 6.9e-29 102.3 In-house 84-272 (272) Show / Hide 
Range on Protein: 119-285
Range on HMM: 84-272/272
Sequence Identity: 30% (59 aa)

DMFDFIKGQGK--------------------ISEDMARFLFRQIAVTVHECVQNRVLHRDLKDENIVIDLVTGSTKLIDFGAATVLRRSQ-YSDFQGTRL
.||| .  .|.                    ..|. ||. | ||.  || | .  . ||||| ||| .|      |..|||        |  . . |.  
EMFDYLCKHGRKGVKMVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNM-NIKIADFGFSNWFKQGQLLMTWCGSPP

YCPPEWFLHSLYLGREAAVWSLGVLLYNSLNGRLPFRNEKD--ICTAHLLGP--LPFFVPVSAEVKDLISKCLTFDPFQRCSLEAILNHPWV
|  || |.   | | .. .||.||.||    | ||| .. .       | |   .|||  .| .  .|| . |. || .| . . |..|.| 
YAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFF--MSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase prk-2.AA MARK 31-72 23 3.5e-08 23.02 In-house 1-43 (262) Show / Hide 
Range on Protein: 31-72
Range on HMM: 1-43/262
Sequence Identity: 23% (10 aa)

YKLKAELGRGGFGVVYRAVRTCDNALVAVKFIERSNVKE-WAR
||.. ..| |....|. |. .. .  ||.|..|. .  . ...
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWM
Kinase prk-2.AA TyrKc 31-290 17 9.2e-08 -97.12 SMART 1-280 (280) Show / Hide 
Range on Protein: 31-290
Range on HMM: 1-280/280
Sequence Identity: 17% (54 aa)

YKLKAELGRGGFGVVYRAVRTCDNALVAVKFIERSNVKEWARINGEQVPMEICMLAKC-SKVRGVIRLLDWYSIP-------EGFLIVMERPYPCIDMFD
 .|. .||.| ||.||... .     |||| .  .          |    |. .. |   .   ..||.   . .       |  .||||   |  |  |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEY-MPHGDLKD

FIKGQGK-ISEDMARFLFRQIAVTVHECVQNRVLHRDLKDENIVIDLVTGSTKLIDFGAATVLRRS-------QYSDFQ---GTR--L---YCPPEWFLH
...  .. .. .       |||       .... ||||   |. ..      |  ||| .  .          .| . .   |..  |    ..|| . .
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

SLYLGREAA-VWSLGVLLY--NSLNGRLPFR-----NEKDICTAHLLGP--LPFFVP--------VSAEVKDLISKCLTFDPFQRCSLEAILNHPWVKQQ
. .   ..  ||| ||...   .. .  .        . .   ...     .|             ..|. .....|  .|| .|.. ..|        .
GKF--TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-------HE

TL
 .
CF
Kinase prk-2.AA Ciliate-E2 31-68 27 0.000113 11.95 In-house 1-46 (365) Show / Hide 
Range on Protein: 31-68
Range on HMM: 1-46/365
Sequence Identity: 27% (13 aa)

YKLKAELGRGGFGVVYRAVRTCDNALVAVKFIERSN---------VK
||.   .|.|.||.||.. .  .. ..| |.|.  .         ||
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVK
Kinase prk-2.AA QIK 31-69 33 0.01075 6.77 In-house 1-39 (272) Show / Hide 
Range on Protein: 31-69
Range on HMM: 1-39/272
Sequence Identity: 33% (13 aa)

YKLKAELGRGGFGVVYRAVRTCDNALVAVKFIERSNVKE
| .   .|.| |.|| .|      . ||.| | .|   |
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDE