Gene sax-1 (Nematode worm)

sax-1

Species: Nematode worm
Alias: R11G1.4, sax-1, aSWK008, CE31052
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: X: 3653949-3650117, WormBase Genetic Map location: n/a,

Classification

Group: AGC
Family: NDR
Subfamily: NDR

Sequence

Name Sequence Type Origin Length Description Download
sax-1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 295 Kinase domain by global Sugen HMM Fasta, JSON
sax-1.AA Protein Genbank 467 None Fasta, JSON

Protein domain

Protein domains of sax-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase sax-1.AA NDR 80-374 52 5.2e-229 714.5 In-house 1-350 (350) Show / Hide 
Range on Protein: 80-374
Range on HMM: 1-350/350
Sequence Identity: 52% (185 aa)

FESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHVRAERDILSEAD--CDWVVKMYYSFQDYSNLYLVMEFLPGGDMMT---LLIKKDT
||..|.||.||||||.||.|.||||||||||.|||||..|.|.|||||||||..|||  ..||||.|||||| ..||||||..|||||||   ||.|.|.
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LTEEATQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLCTG---------------------LKKFHRTDHYRNWPSTLPPDFI----
.||....||||| ..||  .|..|.|||||||||.|.|..||.||.|||||||                     ... |....|.|.    | ||.    
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNWN

SKPFESKR-----------------KAETWKRNRRAYAYSTVGTPDYIAPEVFQP-NGYTKSCDWWSLGVIMYEMLIGYPPFCSELPQETYRKVINWQQT
|.| ..|.                 ....||.|||..||||||||||.||||||  .||...|||||||.||||||.|||||||. ||||..|..||.||
SNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQT

L-----VFPSDVPISIEAKATIKRFCC-EAERRLGNHG-GLDEIKQCPFV
.      ||.....| ||.  |.|.|| ....|||.|| | ||||..|| 
WDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF
Kinase sax-1.AA AGC 80-374 33 2.4e-184 481.76 In-house 1-395 (395) Show / Hide 
Range on Protein: 80-374
Range on HMM: 1-395/395
Sequence Identity: 33% (136 aa)

FESLKVIGRGAFGEVRLVQKH------DTGHIYAMKILRKSE--------MVEKEQTAH-------VRAERDILSEAD----------CDWVVK-MYYSF
|| |||||.|.||.|.||.|       |||..||||.|.|..        |||. .|.|       |..||.||....          ....|| ..|||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDYSN--LYLVMEFLP--------GGDMMTLLIKKD-----TLTEEATQFYIAE-------AALAIQFIHS-LGFIHRD-IKPDNLLLDARGHVKLSDFG
|| ..  ||.|||..|        ||.....|....     ...||...||.||        .||....|| .|.|||| .||.|.|||..||.||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCTG----------------LKKFHRTDHYRNWPSTLPPDFISKPFESKRKAETWKRNR-----------RAYAYSTVG--TPDYIAPEVFQPNGYTKSC
||.                 ... |.. . . .      ..   . .. .....|.||.           |. ... .|  ||.|.|||..    |.|.|
LCKEGMNDGEKGQQSQSNMKFHW-HNKKY-Q-KS-----NMD--T-NK-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKAC

DWWS--LGVIMYEMLIGYPPFCSELPQ----------ETYRKVI------NWQQTL------VFPSDVPISIEAKATIKRFCC-EAERRLGNHG------
||||  ||..|||||.|||||... ||          |.. |..      ||....       || |. .| |||  ||...| . |.|||..|      
DWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDK

GLDEIKQCPFV
| .|||. |. 
GAEEIKNHPWF
Kinase sax-1.AA DMPK 80-225 50 1e-108 269.71 In-house 1-147 (270) Show / Hide 
Range on Protein: 80-225
Range on HMM: 1-147/270
Sequence Identity: 50% (74 aa)

FESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHVRAERDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKD-TLTEE
|| |||||||.|||| .|.   |. .||||.. | ||. ...|| .. ||||.. ... |... .| |||  .||.|||. ||||. ||. . .  . |.
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED

ATQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLC
 ..||.||  |||  ||..|..|||||||| ||| .||.|| ||| |
MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFGSC
Kinase sax-1.AA S_TKc 80-374 32 3.3e-99 336.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 80-374
Range on HMM: 1-231/231
Sequence Identity: 32% (99 aa)

FESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHVRAERDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPG--GDMMTLLIKKDT---
.| |..||.||||.|.......||.|.|.||..           |.| |..||.. .....||.|..||| ..||.|||...|  ||..... |. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTEEATQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLCTGLKKFHRTDHYRNWPSTLPPDFISKPFESKRKAETWKRNRRAYAY
   ..|  ..||... ..|....||.|.||||.||.|.|||   |.|..||||.. |                                          .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------------------------T

STVGTPDYIAPEVFQPNGYTK-SCDWWSLGVIMYEMLIGYPPFCSELPQETYRKVINWQQTLVFPSDVPISIEAKATIKRFCC-EAERRLGNHGGLD---
. .|||.|.||||.   ||.| .|||||.|.|.|||| |||||.   .|....|.               | |||  |.. .. . |.|..    |    
TFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEW

EIKQCPFV
.||. |..
DIKCHPWF
Kinase sax-1.AA RSK 83-374 34 2.7e-95 322.9 In-house 1-278 (278) Show / Hide 
Range on Protein: 83-374
Range on HMM: 1-278/278
Sequence Identity: 34% (107 aa)

LKVIGRGAFGEVRLVQKH---DTGHIYAMKILRKSEMVEKEQ-TAHVRAERDILSEAD-CDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKDT---
||| |.|..|.| |..|    |||.|||||.|.|...| ..  |.|...||.||..   .  .|. .|.||. . |||.||...||.. | | |. .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LTEEATQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDA---RGHVKLSDFGLCTGLKKFHRTDHYRNWPSTLPPDFISKPFESKRKAETWKRNR-RAYA
..|.  .||.|| .||....|..|.||||.||.| |.|    .||.||.|||.|  .                                   |..    .
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-----------------------------------RCDHNQWT

YSTVGTPDYIAPEVFQ----PNGYTKSCDWWSLGVIMYEMLIGYPPFCS---ELPQETYRKVINWQQTLVFPSDVPISIEAKATIKR-FCCEAERRLG-N
.. ..| .|.|||.      ..|..|.||||||||.||||| |.||| .   . ..|. ... . . .| .| .  .| |||  |.. .. . ..||| .
MTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCG

HGGLDEIKQCPFV
.....|||| |. 
PQDAEEIKQHPWF
Kinase sax-1.AA MAST 80-224 43 8.7e-78 237.06 In-house 1-148 (337) Show / Hide 
Range on Protein: 80-224
Range on HMM: 1-148/337
Sequence Identity: 43% (64 aa)

FESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHVRAERDILSEADCDWVVKMYYSFQD--YSNLYLVMEFLPGGDMMTLLIKKD-TLT
|| .|.|..||.| | ||.. .|. ..|||..... .  | |  .|..||.||.......||||.||||      |..|||.. |||  .||     .. 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EEATQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGL
|. ...||||  |.. ..|| | .|||.||||.|.|. ||.|| ||||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGL
Kinase sax-1.AA MAST 80-224 45 1.8e-77 249.21 In-house 1-145 (334) Show / Hide 
Range on Protein: 80-224
Range on HMM: 1-145/334
Sequence Identity: 45% (66 aa)

FESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHVRAERDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKDTLTEEA
||  |.|..||.| | || . .|. ..|||...||.|  | .. .|..||.||.......||||.||||  ..|..|||.. |||  .||    .. |. 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

TQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGL
...|||| .|.....|| | .|||.||||.|.|. ||.|| ||||
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGL
Kinase sax-1.AA Pkinase 80-374 25 7.6e-75 259.76 Pfam 1-293 (293) Show / Hide 
Range on Protein: 80-374
Range on HMM: 1-293/293
Sequence Identity: 25% (84 aa)

FESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHVR-AERDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPGG----DMMTLLI--KK
.. ...||.|.||.|.. ....||.|.|.||..|..  .... .|.| .|  |. . ... .|..|..|.| ...|.|||...||    | ....   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

DTL--TEEATQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHV----KLSDFGLCTGLKKFHRTDHYRNWPSTLPPDFISKPFESKRKAETWKRNR
 ..  .|.  .||. . . .....|| |.||||.||.|.|.| .||.    |..||||.  ..                                    .
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------------------------------Y-N

RAYAYSTVGTPDYIAPEVFQ-PNGYTKSCDWWSLGVIMYEMLIGYPPFCSE------LPQETYRKVINWQQTLVFPSDVPIS-----------------I
   ... .|||.|.|||| .  ..|....|.||.|.|.|||| |.|||...       ... ....   .    .| . .||                  
NS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSE

EAKATIKRFCC-EAERRLGNHGGLDEIKQCPFV
|.|  ||. .|   ..|..     ..|.| |..
ECKDFIKWCLCKDPKKRPT----AEQILQHPWF
Kinase sax-1.AA Akt 80-235 42 7.6e-69 219.18 In-house 1-160 (264) Show / Hide 
Range on Protein: 80-235
Range on HMM: 1-160/264
Sequence Identity: 42% (68 aa)

FESLKVIGRGAFGEVRLVQKHDTGHIY-AMKILRKSEMVEKEQTAHVRAERDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKDTLTEE
|. |||.|.|.|| | ||.| ||. .| |||.|.|.  ..| | .|. .|| ||   ..  .|...||||.  .||.||.. .||.  ..| .| . .|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

ATQFYIAEAALAIQFIHSLGFIHRD-IKPDNLLLDARGHVKLSDFGLCT-G-LKKFHRTD
 . ||.||  |||.. || . | ||  || |.|.|. ||..| |||||  . .| ...|.
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTK
Kinase sax-1.AA GEK 80-230 53 3.5e-67 224.45 In-house 1-152 (269) Show / Hide 
Range on Protein: 80-230
Range on HMM: 1-152/269
Sequence Identity: 53% (81 aa)

FESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHVRAERDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIK-KDTLTEE
|| ||||||||||||  |. ..|...|||||| | ||. .  ||  | |||.| . |. |. .. | |||  .|||||..  |||..||| | .| | |.
FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED

ATQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLCTGLKK
  .|||||  .||. .| |...||||||||.||| .||..| ||| |  ..|
MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFGSCLRMNK
Kinase sax-1.AA CRIK 80-223 44 6.7e-63 199.23 In-house 1-145 (272) Show / Hide 
Range on Protein: 80-223
Range on HMM: 1-145/272
Sequence Identity: 44% (64 aa)

FESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHVRAERDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKD-TLTEE
||   .||.| ||.| .|    |. |||||...|...  .|| . .  ||||.| .   |. .  | |||  ||||.||. ||||   |.   |  . |.
FEVKDLIGCGHFGQVQVVREKQTNDIYAMKVMHKKVVLAQEQVSFFEEERDIMSRRNSPWLPQLQYAFQDNDNLYLMMEYHPGGDLLSLMNRHDDQFDEN

ATQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFG
  .|| ||  .|.  .|  |..||||||.| |.|  ||.|| |||
MARFYLAELIVAVHSLHEMGYVHRDIKPENILIDRTGHIKLADFG
Kinase sax-1.AA ROCK 80-225 50 1.9e-62 211.44 In-house 1-145 (263) Show / Hide 
Range on Protein: 80-225
Range on HMM: 1-145/263
Sequence Identity: 50% (74 aa)

FESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHVRAERDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKDTLTEEA
|. .|||||||||||.|| .. . ..||||.| | ||. .   |    ||||.  |  .|.|...| |||   ||.||...||||.. |. . | . |  
FHMIKVIGRGAFGEVQLVRHKSSKKVYAMKMLSKFEMIKRSDSAFFWEERDIMAHANSEWIVQLHYAFQDDRYLYMVMDYMPGGDLVNLMSNYD-VPEKW

TQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLC
..|| .|  ||.. |||.||||||.||||.|||  ||.|| ||| |
ARFYTMEVVLALDAIHSMGFIHRDVKPDNMLLDKYGHLKLADFGTC
Kinase sax-1.AA DMPK 274-374 44 6.9e-52 126.0 In-house 162-270 (270) Show / Hide 
Range on Protein: 274-374
Range on HMM: 162-270/270
Sequence Identity: 44% (49 aa)

VGTPDYIAPEVFQPNGYT------KSCDWWSLGVIMYEMLIGYPPFCSELPQETYRKVINW-QQTLVFPSDVP--ISIEAKATIKRFCCEAERRLGNHGG
|||||||.||| |  .        ..|||||.||.||||| |  ||  .   ||| |  |  .  | ||.|..  .| |||  |... |..|.|||  .|
VGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLG-RNG

LDEIKQCPFV
....|. || 
YEDFKCHPFF
Kinase sax-1.AA ROCK 274-374 47 3.4e-33 110.21 In-house 160-263 (263) Show / Hide 
Range on Protein: 274-374
Range on HMM: 160-263/263
Sequence Identity: 47% (50 aa)

VGTPDYIAPEVFQPNG----YTKSCDWWSLGVIMYEMLIGYPPFCSELPQETYRKVINWQQTLVFPSDVPISIEAKATIKRFCCEAERRLGNHGGLDEIK
|||||||.||| .  |    | . ||||| || .||||.|  ||  .    || |... .. | || || || .||. |..|  ..|.||| . |.|.||
VGTPDYISPEVLKSQGQDGEYGRECDWWSVGVFIYEMLVGDTPFYADSLVGTYSKIMDHKNSLKFPDDVEISKQAKDLICKFLTDREQRLGRN-GVDDIK

QCPFV
| .| 
QHKFF
Kinase sax-1.AA GEK 274-374 45 6.8e-33 107.45 In-house 162-269 (269) Show / Hide 
Range on Protein: 274-374
Range on HMM: 162-269/269
Sequence Identity: 45% (50 aa)

VGTPDYIAPEVFQPNG-----YTKSCDWWSLGVIMYEMLIGYPPFCSELPQETYRKVINWQQTLVFPSDVP---ISIEAKATIKRFCCEAERRLGNHGGL
|||||||.||. |  .     | . ||||||||.||||| |  || .|   ||| |..|... . |||..    .| |||  |..  |..|.||| ..|.
VGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLG-RNGI

DEIKQCPFV
.. |. || 
QDFKKHPFF
Kinase sax-1.AA MAST 274-374 43 6.8e-32 94.21 In-house 229-337 (337) Show / Hide 
Range on Protein: 274-374
Range on HMM: 229-337/337
Sequence Identity: 43% (48 aa)

VGTPDYIAPEVFQPNG-YTKSCDWWSLGVIMYEMLIGYPPFCSELPQE-TYRKVINWQQTLVFPSD------VPISIEAKATIKRF-CCEAERRLGNHGG
.||||||||||    | | |. ||||.|.|||| |.|.|||  . |.| .  ..|| .  . .|..       ..| ||.  ||..       |||   |
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGAN-G

LDEIKQCPFV
 ||||| || 
ADEIKQHPFF
Kinase sax-1.AA MAST 274-374 40 4.7e-30 93.82 In-house 225-334 (334) Show / Hide 
Range on Protein: 274-374
Range on HMM: 225-334/334
Sequence Identity: 40% (44 aa)

VGTPDYIAPEVFQPNG-YTKSCDWWSLGVIMYEMLIGYPPFCSELPQETYRKVINWQ--QTLVFPS-----DVPISIEAKATIKRF-CCEAERRLGNHGG
.||||||||||    | . |. ||||.|.|||| |.|.|||. . |.|.. ...|    ..   .      |  .| ||.  |...  .  . |||  .|
CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNG

LDEIKQCPFV
 ||.|| ||.
ADEVKQHPFF
Kinase sax-1.AA CRIK 274-360 39 2.2e-26 80.83 In-house 162-262 (272) Show / Hide 
Range on Protein: 274-360
Range on HMM: 162-262/272
Sequence Identity: 39% (40 aa)

VGTPDYIAPEVFQP-NG-------YTKSCDWWSLGVIMYEMLIGYPPFCSELPQETYRKVIN------WQQTLVFPSDVPISIEAKATIKRFCCEAERRL
||||||.|||| |  ||       |  .|||||.|.| ||| .|  ||      .|| ...|       |  | || | ..| ..   |.   |.   ||
VGTPDYMAPEVLQTMNGYKLSKGMYGVDCDWWSMGIIAYEMMCGKTPFHEDNMHRTYSNIMNHCEESHFQRFLSFPDDPKVSPNYRDLIQSLLCNQSKRL

G
.
K
Kinase sax-1.AA Akt 270-313 53 2.8e-23 71.18 In-house 159-203 (264) Show / Hide 
Range on Protein: 270-313
Range on HMM: 159-203/264
Sequence Identity: 53% (24 aa)

AYSTVGTPDYIAPEVFQPNGYTKSCDWWS-LGVIMYEMLIGYPPF
...  ||| |.|||. . ||.||..|||. ||..||||. | |||
TKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPF
Kinase sax-1.AA Pkinase_Tyr 80-225 27 7.9e-14 47.45 Pfam 1-158 (270) Show / Hide 
Range on Protein: 80-225
Range on HMM: 1-158/270
Sequence Identity: 27% (44 aa)

FESLKVIGRGAFGEVRLVQKH----DTGHIYAMKILRKSEMVEKE--QTAHVRAERDILSEA-DCDWVVKMYYSFQ-DYSN--LYLVMEFLPGGDMMTLL
 . .|..|.||||||..   .    .|.   | |.| |    ...  . .  | |  |...  ... .|..|     .     .|.|||. |.||. . |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

IK----KDTLTEEATQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLC
 |    |. || .    . .. | . .. .| ..||||.   | |..  ..|| .||||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase sax-1.AA Pkinase_C 392-439 37 1e-11 44.47 Pfam 1-46 (46) Show / Hide 
Range on Protein: 392-439
Range on HMM: 1-46/46
Sequence Identity: 37% (19 aa)

TVKSIDDTSNFD-DFPDEDLTW--PTSTLIRPEEQPGRRGEFVDFTYKRFD
.|||..|||||| .| ||. .   |... .....|     .|..|||...|
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQE----PFRGFTYVNPD
Kinase sax-1.AA TyrKc 80-359 18 1.5e-11 -35.82 SMART 1-280 (280) Show / Hide 
Range on Protein: 80-359
Range on HMM: 1-280/280
Sequence Identity: 18% (61 aa)

FESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHVRAERDILSEA--DCDWVVKMYYSFQDY-------SNLYLVMEFLPGGDMMTLLI
 . .|..|.||||||.. .        | | |...        .  . |  |...   . . .|..|    .          |..|||. |.||    | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KKDT-LTEEATQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLCTGLKKFHRTD-HYRNWPSTLPPDFISKPFESKRKAETWKRNRRA
|.   |. .    .   .|   ...|| ..||||.   | |......|| |||||.    ...  | .                               .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLS----RDIYDDDQQG----------------------------ES

YAYSTV----GTPD-----YIAPEVFQPNGYTKSCDWWSLGVIMYEML-IGYPPFCSE----LPQETYRKVINWQQTLVFPSD--------VPISIEAKA
  | ..    |. .       |||... . .|   | || || |.|..  | .|   .    .. .  .. .     .  | .         |  .    
KDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ--

TIKRFCCE----------AERRL
 .|. . |            ...
IMKQCWHEDPEDRPTFSEIHECF
Kinase sax-1.AA S_TK_X 375-437 23 1.4e-08 35.7 SMART 1-79 (79) Show / Hide 
Range on Protein: 375-437
Range on HMM: 1-79/79
Sequence Identity: 23% (21 aa)

KRIDWNHIR----ERPPPIRVTVK----SIDDTSNFD-DFPDEDLTWPTSTLIRPEEQPGRR-----------------GEFVDFTYKR
. |||....    | .||.. ..|    |  |||||| .|..|. .          ..|  .                  .| .|||..
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM----------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase sax-1.AA Akt 356-374 35 0.005959 5.18 In-house 245-264 (264) Show / Hide 
Range on Protein: 356-374
Range on HMM: 245-264/264
Sequence Identity: 35% (7 aa)

ERRLG-NHGGLDEIKQCPFV
..|||  .....|||. |. 
KKRLGGGPNDAQEIKRHPWF
Kinase sax-1.AA Pkinase_Tyr 281-325 31 1.517808 2.47 Pfam 182-228 (270) Show / Hide 
Range on Protein: 281-325
Range on HMM: 182-228/270
Sequence Identity: 31% (15 aa)

APEVFQPNGYTKSCDWWSLGVIMYEMLI-GYPP-FCSELPQETYRKV
|||... . .|   | || || |.|..  |  | .    ..| |...
APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI