Gene T01A4.1 (Nematode worm)

T01A4.1

Species: Nematode worm
Alias: CE25977, T01A4.1, T01A4.1b, aSWK281
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: I:-1.05, WormBase Physical Map location: I: 4498009-4508257

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
T01A4.1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 279 Kinase domain by global Sugen HMM Fasta, JSON
T01A4.1.AA Protein Genbank 637 None Fasta, JSON

Protein domain

Protein domains of T01A4.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase T01A4.1.AA RGC 122-385 43 6.9e-144 484.32 In-house 1-300 (300) Show / Hide 
Range on Protein: 122-385
Range on HMM: 1-300/300
Sequence Identity: 43% (130 aa)

KGVVVAIKKLNIDPKKYPRLDLSRAQLMELKKMKDLQHDHITRFTGACIDFP------HYCVVTEYCPKGSLEDILENEKIELDKLMKYSLLHDLVKGLF
.|..|.|||.|.....  ..|..|....|||.|..||||....| |.||| |      ..|.|.|||..|||.|||||. |..|   |||...|.|||. 
EGDWVWIKKHNQRNLF-RHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQ

FLHNSEIRSHGRLKSSNCVVDSRFVLKVTDFGL-----HRLHCLEEI---------NLEEIGEHAYYKKMLWTAPELLR-DSNAPPMG--------TQKG
.||.|.||.||.|||.|||||||.|.|.|||||     |.... ..          .... .||.|||||||||||.|| . . ...|        ||||
YLHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKG

DIYSFAIILHEMMFRKGVFALE-------NEDLSPNEIVQRVRKPVS-EDQEPLRPWVSETGEGEGDDALNDTLLSLMVACWSEDPHERPE-VSSVRKAV
|.|||.||..|...|||.. ||       . .||| ||...|..|.. . | |.||...|. ||. ....|..||.|| .||.|||.|||.  ...||..
DVYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGH-MIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQL

RS
..
KT
Kinase T01A4.1.AA RGC 122-385 43 6.9e-144 484.32 In-house 1-300 (300) Show / Hide 
Range on Protein: 122-385
Range on HMM: 1-300/300
Sequence Identity: 43% (130 aa)

KGVVVAIKKLNIDPKKYPRLDLSRAQLMELKKMKDLQHDHITRFTGACIDFP------HYCVVTEYCPKGSLEDILENEKIELDKLMKYSLLHDLVKGLF
.|..|.|||.|.....  ..|..|....|||.|..||||....| |.||| |      ..|.|.|||..|||.|||||. |..|   |||...|.|||. 
EGDWVWIKKHNQRNLF-RHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQ

FLHNSEIRSHGRLKSSNCVVDSRFVLKVTDFGL-----HRLHCLEEI---------NLEEIGEHAYYKKMLWTAPELLR-DSNAPPMG--------TQKG
.||.|.||.||.|||.|||||||.|.|.|||||     |.... ..          .... .||.|||||||||||.|| . . ...|        ||||
YLHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKG

DIYSFAIILHEMMFRKGVFALE-------NEDLSPNEIVQRVRKPVS-EDQEPLRPWVSETGEGEGDDALNDTLLSLMVACWSEDPHERPE-VSSVRKAV
|.|||.||..|...|||.. ||       . .||| ||...|..|.. . | |.||...|. ||. ....|..||.|| .||.|||.|||.  ...||..
DVYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGH-MIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQL

RS
..
KT
Kinase T01A4.1.AA TKL 119-383 18 3.2e-36 126.66 In-house 12-364 (364) Show / Hide 
Range on Protein: 119-383
Range on HMM: 12-364/364
Sequence Identity: 18% (69 aa)

AIFKG----------VVVAIKKLNIDPKKYPRLDLS----------------------RAQLMELKKMKDLQHDHITRFTGACIDFPH------------
....|           .||.||....  .   . .                            |.. |. |.|..| .| |.|.. |.            
GKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWG

-YCVVTEYCPKGSLEDILENEKIELDKLMK-YSLLHDLVKGLFFLHNSEI-------RSHGRLKSSNCVVDSRFV--------------LKVTDFGLHRL
 .| |.||||.|||...|         . .  .. .|  .|. .||...          |  |||.|. ||. .               .|..|||| | 
QLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRF

HCLEEINLEE-----------IGEHAYYKKM---LWTAPELLRDSNAPP------------MGTQKGDIYSFAIILHEMMFRKGVFA-LENEDLSPN---
.. .. .               .. . ...     | |||.||...  .              ..| |.|||.|.| |.. |. ... . ...  ..   
MSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPF

EIVQRVRKPVSEDQEPLRP--WVS-ETGEGEGDDALND--TLLSLMVACWSEDPHERPEVSSVRKAV
|. . ..  ... . |..|  | . .  .    .  .    . .||  ||..||..||  . . |  
EEMFMMV--CDKGLRPPIPPIWQNHH--K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase T01A4.1.AA TKL-Unique 119-304 30 2.3e-33 115.09 In-house 16-221 (290) Show / Hide 
Range on Protein: 119-304
Range on HMM: 16-221/290
Sequence Identity: 30% (64 aa)

AIFKGVVVAIKKLNIDPKKYPRLDLSRAQLMELKKMKDLQ-HDHITRFTGACI----DFPHYCVVTEYCPKGSLEDILE---------NEKIELDKLMKY
....|  ||||....  .  .......   .|.. || |. |. |... |.|.    . |..| |.|||| ||| | |          |....|. ....
GKWRGYPVAIKQFHP--NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRV

SLLHDLVKGLFFLHNSE--IRSHGRLKSSNCVVDSR-----FVLKVTDFGLHRLHCLEEINLEEIGEH------AYYKKMLWTAPELLRDSNAPPMGTQK
.. .| ..|. .||..|  |  |. |||||  ||..     .  |. |||| ..  .  || . ..||         .  .| |||.||...   . ..|
KMAIDIAQGMYYLHHCEPPI-IHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKF--NSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNF--CQYSEK

GDIYSFAIILHEM
 |.|||.|.| |.
SDVYSFGIVLWEI
Kinase T01A4.1.AA DRK 154-248 41 1.3e-19 63.16 In-house 51-146 (258) Show / Hide 
Range on Protein: 154-248
Range on HMM: 51-146/258
Sequence Identity: 41% (40 aa)

MKDLQHDHITRFTGACIDFPHYCVVTEYCPKGSLEDILENEKIELDKLMKYSLLHDLVKGLFFLHNSE-IRSHGRLKSSNCVVDSRFVLKVTDFGL
|. | |  |  | |.|   |  |...|| |.|||  || .|.||.|     ..  |  ||. .||... |  |  ||| |  ||  .  || ||||
MCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGL
Kinase T01A4.1.AA Dicty4 154-248 35 2.4e-19 61.35 In-house 52-160 (277) Show / Hide 
Range on Protein: 154-248
Range on HMM: 52-160/277
Sequence Identity: 35% (39 aa)

MKDLQHDHITRFTGACI----DFPHYCVVTEYCPKGSLEDILEN------EKIELD-KLMKY--SLLHDLVKGLFFLHNSE-IRSHGRLKSSNCVVDSRF
|. ..| .|  | |||.      .  | ||||.|||.|. .| .      ..|.||  |.|    .  | ..|.  ||..  .  |  |||.|  ||  .
MCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNW

VLKVTDFGL
. ||.||||
RVKVCDFGL
Kinase T01A4.1.AA TKL-ciliate2 119-307 29 1.9e-17 54.29 In-house 18-214 (273) Show / Hide 
Range on Protein: 119-307
Range on HMM: 18-214/273
Sequence Identity: 29% (62 aa)

AIFKGVVVAIKKLNIDPKKYPRLDLSRAQLMELKKMKDLQHDHITRFTGACIDFPHYCVVTEYCPKGSLEDILENEKIELDKLMKYSLLHDLVKGLFFLH
| .. .|||.||  .|   .   .  |  . | . |  | |  |  | ||| . | .|.. ||| .|||  .| |. . |    .  .  |  .| ..||
AKWREIVVAVKKFKMD---HDNQQQIRDFVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQNQDVRLTWEDRRRIALDIARGVHYLH

NSEIRS-HGRLK--------------------SSNCVVDSRFVLKVTDFGLHRLHCLEEINLEEIGEHAYYKKMLWTAPELLRDSNAPPMGTQKGDIYSF
 |.    |  ||                    | | .||  |  |.||||  |    .      ||         | ||| ..      . | | |..|.
SSNPPIIHRDLKRQIKHKEKNLINIITLIKINSLNVLVDDNFRCKLTDFGWTRVKPQDNYMTNKIGTYQ------WMAPEVIKAF----YYTEKADVFSY

AIILHEMMFR
.||| |.  |
SIILWEIASR
Kinase T01A4.1.AA TK 148-305 15 1.5e-16 51.26 In-house 89-388 (486) Show / Hide 
Range on Protein: 148-305
Range on HMM: 89-388/486
Sequence Identity: 15% (48 aa)

LMELKKMKD--LQHDHITRFTGACIDF------------PHYCVVTEYCPKGS----LEDILENEKIE--------------------------------
..|.|.|.   ..|..| |. |.| .             .....|.||.|.|.    | | | . . .                                
AEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSH

-------------------------------------------LDKLMKYSLLHDLVKGLFFLHNSEIR-----SHGRLKSSNCVVDSRFV---------
                                           |.   .    ... .|. .||   ..      |. |   || |... |         
ESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCG

--LKVTDFGLH------RLHCLEEINLEEIGE----------------HAYYKK----ML---WTAPELLRD---SNA--PPMGTQKGDIYSFAIILHEM
   |..||||       .   ...       .                ..||..    .|   |.||| |.|   | |      | | |..|| . ..|.
PVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEI

M
.
F
S_TKc T01A4.1.AA S_TKc 90-385 16 3e-15 46.73 SMART 1-231 (231) Show / Hide 
Range on Protein: 90-385
Range on HMM: 1-231/231
Sequence Identity: 16% (52 aa)

SFGMVSFKSGSGGSVETIAQNNTQIYTKTAIFKGVVVAIKKLNIDPKKYPRLDLSRAQLMELKKMKDLQHDHITRFTGACIDFPHYCVVTEYCPK--GSL
   .    .|. |.|     ..           | .||||...            .  . |.. .|  .|..| .. ... |  |...|.|||.   |.|
YEILRKIGKGAFGKVYKCRHKK----------TGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDL

EDILENEKIE-----LDKLMKYSLLHDLVKGLFFLHNSEIRSHGRLKSSNCVVDSRFVLKVTDFGLHRLHCLEEINLEEIGEHAYYKKML----WTAPEL
 |.... . .     ..  .  .... ....| ..|.     |  || .|  .|.  ..|..|||| |.                 . .     . |||.
FDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL----------------TTFCGTPWYMAPEV

LRDSNAPPMGTQKGDIYSFAIILHEMMFRKGVFALENEDLSPNEIVQRVRKPVSEDQEPLRPWVSETGEGEGDDALNDTLLSLMVACWSEDPHERPEVSS
|      . |. | |..|. .|| ||. ..  |        .... ....                           . .....  |.  || .|| .  
L------GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG--------------------------SPEAKDFIRKCLQKDPEKRPTA-E

VRK-------AVRS
. .           
ALQDEWDIKCHPWF
Kinase T01A4.1.AA MLK 125-250 24 6.9e-15 48.2 In-house 29-181 (291) Show / Hide 
Range on Protein: 125-250
Range on HMM: 29-181/291
Sequence Identity: 24% (38 aa)

VVAIKKLNIDP----KKYPRLDLSRAQLMELKKMKDLQ-HDHITRFTGACIDFPH-YCVVTEYCPKGSLEDILENEK---------------IELDKLMK
.||.|. ....    ..|   .  .   ..|.... .  |  | .| |.|.. |. .|.|.|||..||| ..| ...               . .| .|.
IVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMN

YSLLHDLVKGLFFLHNSE----IRSHGRLKSSNCVVDS------RFVLKVTDFGLHR
 .|  .  .|. .||. .    |. .  |||.| ..|         .||..|||. |
WAL--QCARGMHYLHSMAPKPIIHRD--LKSHNILIDEICHDMHHGTLKICDFGTSR
TyrKc T01A4.1.AA TyrKc 84-383 20 2e-14 10.53 SMART 1-280 (280) Show / Hide 
Range on Protein: 84-383
Range on HMM: 1-280/280
Sequence Identity: 20% (68 aa)

LKNRKL----SFGMVSFKSGSGGSVETIAQNNTQIYTKTAIFKGVVVAIKKLNIDPKKYPRLDLSRAQLMELKKMKDL--QHDHITRFTGACIDF-----
..  |      || |     .                       . ||.|.|. |          .. . |.. |. |  .|..| |. |.|..      
ITLGKKLGEGAFGEVYKGTWK-----------------------IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFM

--PHYCVVTEYCPKGSLEDILENEKIELDKLMKYSLLHDLVKGLFFLHNSEIRSHGR-----LKSSNCVVDSRFVLKVTDFGLHRLHCLE-EINLEEIGE
  . ...|.||.|.|.| | | . . .|    . |  ..  .|  .||        .     |   || |..... |..|||| | .  . .       .
YIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSK------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG----ES

HAYYKK----ML-------WTAPELLRDSNAPPMGTQKGDIYSFAIILHEMMFRKGVFALE---NEDLSPNEIVQRVRKPVSEDQEPL-----RPWVSET
. ||.|             |.||| ....    . | | |..|| . . |.. . .    .   . ..|. |....|..    .| |             
KDYYRKKEHKGGKTMLPIRWMAPECINYG----KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSF------

GEGEGDDALNDTLLSLMVACWSEDPHERPEVSSVRKAV
          | . ..|  || |||..||  | ...  
------VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Pkinase T01A4.1.AA Pkinase 98-248 25 3.8e-13 47.56 Pfam 9-158 (293) Show / Hide 
Range on Protein: 98-248
Range on HMM: 9-158/293
Sequence Identity: 25% (42 aa)

SGSGGSVETIAQNNTQIYTKTAIFKGVVVAIKKLNIDPKKYPRLDLSRAQLMELKKMKDLQHDHITRFTGACIDFPHYCVVTEYCPKG----SLEDILE-
||| |.|      .|..          .||.|... . .|   .   |   .|.. || |.|..| |. ... | .|...|.|||..|    .| |... 
SGSFGCVYKCHHKGTGK----------IVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

--NEKI--ELDKLMKYSLLHDLVKGLFFLHNSEIRSHGRLKSSNCVVDSRFVL----KVTDFGL
  . ..  . . . .| .   ...|| ..|.  |  |  ||..|. .|.. ..    |..||||
WRHGCFYFSEWECKFYMY--QILRGLEYCHSMGI-IHRDLKPENILIDNNGHIDACVKICDFGL
Kinase T01A4.1.AA Pkinase_Tyr 148-219 29 1.2e-11 40.06 Pfam 51-129 (270) Show / Hide 
Range on Protein: 148-219
Range on HMM: 51-129/270
Sequence Identity: 29% (23 aa)

LMELKKMKDL-QHDHITRFTGACI-DFPH--YCVVTEYCPKGSLEDILENE---KIELDKLMKYSLLHDLVKGLFFLHN
. |.| || | .|..| |. |.|. .  .  ...|.||.|.|.| | | .    |  |.  .. .  ..  ||. .|..
MREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLES
Kinase T01A4.1.AA RIPK 123-248 27 3.7e-10 30.78 In-house 18-155 (290) Show / Hide 
Range on Protein: 123-248
Range on HMM: 18-155/290
Sequence Identity: 27% (38 aa)

GVVVAIKKLNIDPKKYP-RLDLSRAQLMELKKMKDLQHDHITRFTGACIDF-----PH-YCVVTEYCPKGSLEDILENEK--IELDKL--MKYSLLHDLV
|..||.|  .  ... .     . .|. | |.|. |...|| .  | |..      .  |  |.|| ..|||.. |  .    . . .   .  ..|  .
GDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQHHPDPWPLRCRMIHEIS

KGLFFLHNSE---IRSHGRLKSSNCVVDSRFVLKVTDFGL
 | ..||.     |  |  || .|  ||. |  |. ||||
CGMCYLHSMNPPII--HRDLKPENILVDNNFHVKIADFGL
Kinase T01A4.1.AA Pkinase 275-383 16 2.6e-08 30.49 Pfam 179-293 (293) Show / Hide 
Range on Protein: 275-383
Range on HMM: 179-293/293
Sequence Identity: 16% (21 aa)

APELLRDSNAPPMGTQKGDIYSFAIILHEMMFRKGVFALEN----EDLSPNEIVQRVRK-PVSEDQEPLRP--------WVSETGEGEGDDALNDTLLSL
|||..|     .. ..| |..|. .||.||....  |  .     . ........|... |...| . ...        | . . . .  ..........
APEVIR---GGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHW-H-F-HWTF-HNWSEECKDF

MVACWSEDPHERPEVSSVRKA--V
.  |.  ||..||    . .   .
IKWCLCKDPKKRPTAEQILQHPWF
Kinase T01A4.1.AA RIPK 275-312 37 5.2e-07 19.9 In-house 190-229 (290) Show / Hide 
Range on Protein: 275-312
Range on HMM: 190-229/290
Sequence Identity: 37% (15 aa)

APELLRDSNAPP--MGTQKGDIYSFAIILHEMMFRKGVFA
.||..|..|. |  . | | |.|||||.. | . .| ...
PPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHPYE
Kinase T01A4.1.AA DRK 273-308 50 1e-05 15.47 In-house 168-199 (258) Show / Hide 
Range on Protein: 273-308
Range on HMM: 168-199/258
Sequence Identity: 50% (18 aa)

WTAPELLRDSNAPPMGTQKGDIYSFAIILHEMMFRK
||||| ||.       | | |.|||||.| |.. |.
WTAPEVLRNQRY----TEKADVYSFAIVLWECVTRQ
Kinase T01A4.1.AA TK 361-383 39 2.9e-05 12.75 In-house 464-486 (486) Show / Hide 
Range on Protein: 361-383
Range on HMM: 464-486/486
Sequence Identity: 39% (9 aa)

LMVACWSEDPHERPEVSSVRKAV
||  ||..|| .||  | .... 
LMQQCWHYDPEDRPTFSQLHEQL
Kinase T01A4.1.AA MLK 355-383 31 3.8e-05 13.96 In-house 263-291 (291) Show / Hide 
Range on Protein: 355-383
Range on HMM: 263-291/291
Sequence Identity: 31% (9 aa)

NDTLLSLMVACWSEDPHERPEVSSVRKAV
.. . .||  ||..|||.||  ... .  
PEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase T01A4.1.AA Dicty4 272-304 36 0.000144 11.35 In-house 182-210 (277) Show / Hide 
Range on Protein: 272-304
Range on HMM: 182-210/277
Sequence Identity: 36% (12 aa)

LWTAPELLRDSNAPPMGTQKGDIYSFAIILHEM
.|.||| ..        ..| | |||.|.| |.
CWMAPEVMMHQPY----NEKADVYSFGIVLWEI
Kinase T01A4.1.AA RIPK 358-383 30 0.000947 8.62 In-house 265-290 (290) Show / Hide 
Range on Protein: 358-383
Range on HMM: 265-290/290
Sequence Identity: 30% (8 aa)

LLSLMVACWSEDPHERPEVSSVRKAV
. .||  ||. || .||    ..  .
MIELMQRCWQQDPNDRPCFQECEEWT
Kinase T01A4.1.AA DRK 361-385 36 0.001397 8.04 In-house 234-258 (258) Show / Hide 
Range on Protein: 361-385
Range on HMM: 234-258/258
Sequence Identity: 36% (9 aa)

LMVACWSEDPHERPEVSSVRKAVRS
||  ||.|||  ||    . .   .
LMNDCWNEDPQHRPSMQECLERLEA
Kinase T01A4.1.AA Dicty4 360-374 46 0.0027 7.04 In-house 250-264 (277) Show / Hide 
Range on Protein: 360-374
Range on HMM: 250-264/277
Sequence Identity: 46% (7 aa)

SLMVACWSEDPHERP
.|.. ||..||  ||
HLIQWCWDHDPQHRP
Kinase T01A4.1.AA TKL-Unique 361-383 30 0.002972 7.54 In-house 268-290 (290) Show / Hide 
Range on Protein: 361-383
Range on HMM: 268-290/290
Sequence Identity: 30% (7 aa)

LMVACWSEDPHERPEVSSVRKAV
|. .||  || .|| ......  
LIQQCWHHDPSQRPSFDEIIHRL
Kinase T01A4.1.AA Pkinase_Tyr 232-305 28 0.018785 8.93 Pfam 141-208 (270) Show / Hide 
Range on Protein: 232-305
Range on HMM: 141-208/270
Sequence Identity: 28% (23 aa)

NCVVDSRFVLKVTDFGLHRLHCLEEINLEEIGEHAYY-KKML-------WTAPELLRDSNAPPMGTQKGDIYSFAIILHEMM
|| |.. .| |..|||| |..           .  || .|         |.||| ....      | | |..|| . . |..
NCLVTENNVVKICDFGLARDI----------YNDDYYYRKRGGGKLPIKWMAPECINYGK----FTTKSDVWSFGVLMWEIF
Kinase T01A4.1.AA Pkinase_Tyr 360-383 37 0.018785 8.93 Pfam 247-270 (270) Show / Hide 
Range on Protein: 360-383
Range on HMM: 247-270/270
Sequence Identity: 37% (9 aa)

SLMVACWSEDPHERPEVSSVRKAV
.||  || .|| .||  | ..   
DLMKQCWHYDPEDRPTFSEIHEQL
Kinase T01A4.1.AA MLK 289-305 35 0.026545 3.95 In-house 214-230 (291) Show / Hide 
Range on Protein: 289-305
Range on HMM: 214-230/291
Sequence Identity: 35% (6 aa)

TQKGDIYSFAIILHEMM
. | |..|....| ||.
SEKCDVWSWGVVLWEML
CYCc T01A4.1.AA CYCc 423-629 42 1.5e-92 314.66 SMART 1-231 (231) Show / Hide 
Range on Protein: 423-629
Range on HMM: 1-231/231
Sequence Identity: 42% (101 aa)

AEKKKVEELLHQLLPPAIADTLIAGR-AVQAESYDCVTIYFSDIVGFTSLSSQSTPMQVVTLLNDLYLAFDGVVDNFK-----VYKVETIGDAYMVVSGL
.||.| ..||.|.||. .|. | .|| .|....||||||.|.||||||.|.|..||||||..|||.| .|| ..|...     .|||||||||||||||.
MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC

PERRD--------------------DHANQIAQMSLSLLHKVKNFVIRHR----PHEQLKLRIGMHSGSVVAGVVGSKMPRYCLFGDTVNTSSRMESNGL
|.|.                     .|| .||...|  .  .|.| ..|.    |...|..|||.|.|.||.|||| .|||||.||||||. |||||.|.
PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD

RMFWNFSLYKIYKFKVFKNKI--ELDFLKNEKESIEFEG
 .       .|   . .....    .| ..... .|||.
PG-------QIHVSEETYWCLCLD-QFERRRCGQFEFEP
Guanylate_cyc T01A4.1.AA Guanylate_cyc 450-592 46 7.5e-78 269.75 Pfam 1-162 (214) Show / Hide 
Range on Protein: 450-592
Range on HMM: 1-162/214
Sequence Identity: 46% (75 aa)

VQAESYDCVTIYFSDIVGFTSLSSQST----PMQVVTLLNDLYLAFDGVVDNF--KVYKVETIGDAYMVVSGLPER------RDDHANQIAQMSLSLLHK
|.|..||||||.|.||||||...|...    |||.|..|||.|  || ..|..   .|||.||||.||.|||||..      . .|| ..|.|.| ..  
VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY

VKNFVIRHRPHEQ-----LKLRIGMHSGSVVAGVVG--SKMPRYCLFGDTVNTSSRMESNGL
.. . . | . |.     ...|||.|.|.|||||.|  ..|||||..|||||. |||||.|.
CQQVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGV
HNOBA T01A4.1.AA HNOBA 424-444 42 0.000305 16.91 Pfam 214-234 (234) Show / Hide 
Range on Protein: 424-444
Range on HMM: 214-234/234
Sequence Identity: 42% (9 aa)

EKKKVEELLHQLLPPAIADTL
|||| ..||.. .|. .|. |
EKKKTDDLLYSMFPKSVANRL