Gene T01G5.1 (Nematode worm)

T01G5.1

Species: Nematode worm
Alias: CE12974, T01G5.1, aSWK383
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: V:7.29, WormBase Physical Map location: V: 15121255-15119502

Classification

Group: TK
Family: KIN16

Sequence

Name Sequence Type Origin Length Description Download
T01G5.1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 264 Kinase domain by global Sugen HMM Fasta, JSON
T01G5.1.AA Protein Genbank 349 None Fasta, JSON

Protein domain

Protein domains of T01G5.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase T01G5.1.AA KIN16 45-310 42 9.80000000001e-181 534.97 In-house 31-332 (332) Show / Hide 
Range on Protein: 45-310
Range on HMM: 31-332/332
Sequence Identity: 42% (129 aa)

HKNSPTLSIKCALLRNDITHQKMIQDELVTLSSLRSHSCILALVGYVREPN------MLLIVSEHAEHGRLDQFLIDRKLNFNNQLTCSDGSNQKVYNFN
|||......|... ..||..||||.|||........|...|||||.|....      ||.||.|..|.|.|..||.... ||.|...|.|...|..||.|
HKNRLEVAVKSPANPHDICQQKMIYDELKVMCAIGKHPNVLALVGAVTKNMRQGGRHMLMIVTEYVECGDLRKFLRQHRNNFQNHQVCWDNERQSGYNIN

NGE-------------QERISDDMQALCTLDLLSYGYQIAIAMKFLADSRC-LHRALALRSIFVTRNKTIRIGEFGLARINARKEYYIMKS-PQLPLAPE
|.|             |..|.|....||| ||||..||||..|..||...| .||.||.|..|..|||.|||..|||||....|.||.||| ...||...
NKERKHYVFKNFCENEQLVIKDIFDSLCTSDLLSFAYQIANGMEWLAHVPCCVHRDLACRNVFIKRNKIIRIADFGLARWHENKDYYRMKSSMDTPLPMR

VMAPESSED-----KKFTEKSEVRSFAVCLTGIFQLGVPPHEAVNAVYCG----------QDIERKLPELQYCHPDMYSFLSSCWNFDPEARPTYSKCVE
.||||..|.     .||||||.|.|..|||..||.||..|........|.          ......||. ..|||..|.|...|||||||.|||.|.|||
WMAPECFEEEQERKMKFTEKSDVWSYGVCLYEIFSLGETPYPNCPNNNCRDDYFQYVMEYLRKGNRLPQPEHCHPEIYDFMKMCWNFDPEKRPTFSECVE

FF
||
FF
Kinase T01G5.1.AA TK 63-310 18 9.6e-57 188.4 In-house 66-486 (486) Show / Hide 
Range on Protein: 63-310
Range on HMM: 66-486/486
Sequence Identity: 18% (77 aa)

THQKMIQD--------------ELVTLSSLRS----HSCILALVGYVREP------------NMLLIVSEHAEHGR----LDQFLIDRKLNFNNQLTCSD
..|.. .|              |.  .. ...    |  |. |.|.. ..              ..|| |...||     |...| ... .|.... |.|
MSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPD

GSNQKVYNFNNG------------------------EQERISDDMQALCTLDLLS-------------------YGYQIAIAMKFLADS------RCLHR
....|. . . .                        ....|.|. ..|.| |||.                   . .||| .| .|..       .. ||
NQHNKYPPSK-LHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHR

ALALRSIFVTRNKT-----------IRIGEFGLAR---------INARKEYYIMKSPQLPLAPEV-----------------------MAPESSE-----
 || | . |..|..           ..|. |||.|         |. ...|| ..|.  .. .                         ||||. .     
DLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPM-WPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFS

----DKKFTEKSEVRSFAVCLTGIFQLG-VPPHE-AVN---------AVYCGQDIE---------------RKLPELQYCH--------------PDMYS
    ..|||.|| | || |..  || .| .|...   |         .  . .  .                 .|  ..|.              ...| 
EAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYD

FLSSCWNFDPEARPTYSKCVEFF
.. .||..||| ||| | ..|..
LMQQCWHYDPEDRPTFSQLHEQL
TyrKc T01G5.1.AA TyrKc 21-310 25 5.9e-44 153.27 SMART 1-280 (280) Show / Hide 
Range on Protein: 21-310
Range on HMM: 1-280/280
Sequence Identity: 25% (85 aa)

IIEEKEIEH-YYSRIRLGKMKSMGAHKNSPTLSIKCA--LLRNDITHQKMIQDELVTLSSL-RSHSCILALVGYVREP-------NMLLIVSEHAEHGRL
|  .|.. .  . ....|..|            |..|   |..|   .... .|.  ...|  .| .|..|.|.....         |.|| |...|| |
ITLGKKLGEGAFGEVYKGTWK------------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

DQFLIDRKLNFNNQLTCSDGSNQKVYNFNNGEQERISDDMQALCTLDLLSYGYQIAIAMKFLADSRCLHRALALRSIFVTRNKTIRIGEFGLARINARK-
...| ... .                                ||. ||||. .|||  | .|.. .| || || | . |..|.|..|. |||.|    . 
KDYLRKHRPK--------------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDD

------EYYIMK---SPQ--LPLAPEVMAPESSEDKKFTEKSEVRSFAVCLTGIFQLGVPPHEA-----VNAVYCGQDIERK--LPELQY--------CH
      .|| .|   .    ||.    ||||.  ..|||.|| | || ||.  || .| .|..      ...    .....   .|  ..        |.
QQGESKDYYRKKEHKGGKTMLPIR--WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCP

PDMYSFLSSCWNFDPEARPTYSKCVEFF
..||.  ..||..||| ||| | ..|.|
DEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase T01G5.1.AA Pkinase_Tyr 64-310 29 7e-38 128.92 Pfam 47-270 (270) Show / Hide 
Range on Protein: 64-310
Range on HMM: 47-270/270
Sequence Identity: 29% (77 aa)

HQKMIQDELVTLSSLRSHSCILALVGYVR---EPNMLLIVSEHAEHGRLDQFLIDRKLNFNNQLTCSDGSNQKVYNFNNGEQERISDDMQALCTLDLLSY
...... |. ....| .|  |. |.| .    ||| ..|| |...|| |. .| ...                             .| |.|.. |||..
REDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR-----------------------------EDKQPLTMKDLLQM

GYQIAIAMKFLADSRCLHRALALRSIFVTRNKTIRIGEFGLARINARKEYY-IMKSPQLPLAPEVMAPESSEDKKFTEKSEVRSFAVCLTGIFQLGVPP-
 .||| .| .|.. .| || || | . ||.|....|. |||||    ..||  ...    |    ||||.  ..|||.|| | || |..  || .|  | 
CWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPT

------HEAVNAVYCGQDIERKLPELQYCHPDMYSFLSSCWNFDPEARPTYSKCVEFF
      .| ....|      . .|  ..|....|. . .||..||| ||| | ..|..
YPGMSNEEVYEYIYED---GYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase T01G5.1.AA TK-Unique 31-310 21 1.8e-28 95.38 In-house 12-294 (294) Show / Hide 
Range on Protein: 31-310
Range on HMM: 12-294/294
Sequence Identity: 21% (66 aa)

YSRIRLGKMKSMGAHKNSP-TLSIKCALLRNDITHQKMIQDELVTLSSLRSHSCILALVGYVREP-NMLLIVSEHAEHGRLDQFLIDRK-----------
.. .  |....  .| . .    .|    ... | ...  .|.  ...|  |  |. ..|.  .. .  .|. |... |.|. .|  ..           
FGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGN

LNFNNQLTCSDGSNQKVYNFNNGEQERIS------DDMQA-LCTLDLLSYGYQIAIAMKFLAD--SRCLHRALALRSIFVTRNKTIRIGEFGLAR-INAR
|.                         ..      ... . .   ||.....||| .|..||    .. || |. | ...|..|.. |. ||.|| ....
LK-------------------------FDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTN

KEYYIM-KSPQLPLAPEVMAPESSE--DKKF-TEKSEVRSFAVCLTGIFQLGVPPHEAVNAVYCGQDIERK--LPELQYC-HPDMYSFLSSCWNFDPEAR
..|  | ..  .|..   |||||    .. . |.||.| ||.| .  ||.|| .|   . .    ..|..   .|  ..|  ..||....|||. .|| |
GVYSMMCSQGRIPIR--WMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEER

PTYSKCVEFF
|. ....  .
PSFRQIKHRL
Kinase T01G5.1.AA UTK 71-310 22 2.2e-25 83.79 In-house 59-296 (296) Show / Hide 
Range on Protein: 71-310
Range on HMM: 59-296/296
Sequence Identity: 22% (60 aa)

ELVTLSSLRSHSCILALVGYVREPNMLLIVSEHAEHGRLDQFLIDRKLNFNNQLTCSDGSNQKVYNFNNGEQERISDDMQALCTLD-LLSYGYQIAIAMK
||. .. .. |  .| |||..     ..||.|..| | |...| . . ...                          . ... ||. .|.. ..|| .| 
ELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPP--------------------------ACPHWLTLHQRLCMAWDIARGMQ

FLADSRCLHRALALRSIFVTRN-------KTIRIGEFG---LARINAR--------KEYYIMKSPQLPLAPEVMAPESSEDK-KFTEKSEVRSFAVCLTG
.|.  .. || || | ..|...        ...|. ||   ..|  ..          || |...| ...   ||||.  .  .||.|| | || | .  
YLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWE

IFQLGVPPHEAVNAVYCGQDIERK----LPELQYCHPDMYSFLSSCWNFDPEARPTYSKCVEFF
|.. |  | .  ...   . ....    .|  . |  ..|  . .||. ||. ||.    |...
IWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase T01G5.1.AA FAK 157-315 32 6.9e-25 80.18 In-house 126-285 (285) Show / Hide 
Range on Protein: 157-315
Range on HMM: 126-285/285
Sequence Identity: 32% (52 aa)

LLSYGYQIAIAMKFLADSRCLHRALALRSIFVTRNKTIRIGEFGLARINARKEYYIMK-SPQLPLAPEVMAPESSEDKKFTEKSEVRSFAVCLTGIFQLG
|. | ||.. || .|   .. ||  | | . |  .  .. | ||| |    ..||      .||     |.|||     ||  | |  |.||.  |  .|
LILYCYQLCMAMAYLESKKFVHRDIAARNVLVSSPDCVKLGDFGLSRWMHDHSYYKASPKGKLPI--KWMSPESINFRRFTTASDVWMFGVCMWEILMYG

VPPHEAVNAVYCGQDIER--KLPELQYCHPDMYSFLSSCWNFDPEARPTYSKCVEFFDDHFS
| |   |        ||.   ||  . | | .|| .. || .||  || . . ..   | . 
VKPFQWVKNNDVIGRIENGERLPMPPNCPPTLYSLMTRCWAYDPSKRPRFKELKCQLKDIYQ
Kinase T01G5.1.AA Ack 157-310 31 8e-25 80.67 In-house 107-266 (266) Show / Hide 
Range on Protein: 157-310
Range on HMM: 107-266/266
Sequence Identity: 31% (51 aa)

LLSYGYQIAIAMKFLADSRCLHRALALRSIFVTRN-KTIRIGEFGLAR-INARKEYYIMKSPQ---LPLAPEVMAPESSEDKKFTEKSEVRSFAVCLTGI
|. .  ||| .| .|  .||.|| || | | . .  ... |. ||| |     . || |. .    .|.|   .|||.   ..|. .| | .| |.|   
LCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFA--WCAPECLRHRQFSHASDVWMFGVTLWEM

FQLGVPPHEAVNAVYCGQDIE---RKLPELQYCHPDMYSFLSSCWNFDPEARPTYSKCVEFF
|  |  |  ..|.    | |.     ||   .| .| |. .  || ..|. ||| |  ....
FSYGEEPWAGCNGYQILQKIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL
Kinase T01G5.1.AA EGFR 156-311 28 6.3e-24 76.17 In-house 102-258 (258) Show / Hide 
Range on Protein: 156-311
Range on HMM: 102-258/258
Sequence Identity: 28% (46 aa)

DLLSYGYQIAIAMKFLADSRCLHRALALRSIFVTRNKTIRIGEFGLARI-NARKEYYIMKSPQLPLAPEVMAPESSEDKKFTEKSEVRSFAVCLTGIFQL
.|| ...|||  |..| . |  || || | . |   . ..|  ||||.. .. .. | ...  .|     || |. . ...| .| | |. | .  .   
HLLNWCVQIAKGMQYLEEHRMVHRDLAARNVLVKSPNHVKITDFGLAKLLEHDEKEYHAQGGKMPI--KWMALECIHHRCYTHQSDVWSYGVTCWELMTF

GVPPHEAVNAVYCGQDIER--KLPELQYCHPDMYSFLSSCWNFDPEARPTYSKCVEFFD
|  |.. . |    . .|.  .||  . |  |.|  . .||  |.. |||. . .| |.
GQKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDEDMRPTFKELYEEFK
Kinase T01G5.1.AA Frk 163-314 30 7.2e-22 72.29 In-house 106-260 (260) Show / Hide 
Range on Protein: 163-314
Range on HMM: 106-260/260
Sequence Identity: 30% (48 aa)

QIAIAMKFLADSRCLHRALALRSIFVTRNKTIRIGEFGLAR-INARKE--YYIMKSPQLPLAPEVMAPESSEDKKFTEKSEVRSFAVCLTGIFQLGVPPH
|.|  | .| .   .|| || | . |  .. ..| .||||| .   .|  |      ..|.     |||  . .||| ||.| || . || |   |  | 
QVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPI--KWTAPEAANYNKFTIKSDVWSFGILLTEIITYGRMPY

EAVNAVYCGQDIER--KLPELQYCHPDMYSFLSSCWNFDPEARPTYSKCVEFFDDHF
  .      | ...  ..|.   | . .|. .  ||. ||. |||.      ..|.|
PGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase T01G5.1.AA Src-Echino1 146-310 27 1.9e-20 67.26 In-house 87-252 (252) Show / Hide 
Range on Protein: 146-310
Range on HMM: 87-252/252
Sequence Identity: 27% (47 aa)

SDDMQALCTLDLLSYGYQIAIAMKFLADSRCLHRALALRSIFVTRNKTIRIGEFGLARINARKEYYIMKSPQLPLAPEVMAPESSEDKKFTEKSEVRSFA
... . .    |.  | .||  | .|     .|| || | . | .   ..| .|||||.  . .|   .  .||.     |||     .|| ||.| || 
RGKCKHVKMTTLIDMGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPI--KWTAPEAALYGRFTIKSDVWSFG

VCLTGIFQLGVPPHEAVNAVYCGQDIER--KLPELQYCHPDMYSF-LSSCWNFDPEARPTYSKCVEFF
. .| .   |  | . . .    . ..|  ..| .. |   .|   .  ||  ||  |||.    .||
ILMTEMVTFGRYPYPGMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase T01G5.1.AA PDGFR 142-258 39 9.3e-17 49.97 In-house 188-303 (358) Show / Hide 
Range on Protein: 142-258
Range on HMM: 188-303/358
Sequence Identity: 39% (47 aa)

QERISDDMQALCTLDLLSYGYQIAIAMKFLADSRCLHRALALRSIFVTRNKTIRIGEFGLARINARKEYYIMK-SPQLPLAPEVMAPESSEDKKFTEKSE
.| . || ..|   |||.. ||.|  | |||   | || || | . ..  | . |. |||||   .   |. | .  ||.    |||||  |  .| .| 
NELMEDDSNVLTYWDLLCFSYQVAKGMEFLASKNCVHRDLAARNVLLCHGKVVKICDFGLARDIMNDSNYVVKGNARLPV--KWMAPESIFDCVYTTQSD

VRSFAVCLTGIFQLGVPP
| |. . |  || ||. |
VWSYGILLWEIFSLGGNP
S_TKc T01G5.1.AA S_TKc 21-310 17 5.2e-10 -30.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 21-310
Range on HMM: 1-231/231
Sequence Identity: 17% (53 aa)

IIEEKEIEHY-YSRIRLGKMKSMGAHKNSPTLSIKCAL--LRNDITHQKMIQDELVTLSSLRSHSCILALVGYVREPNMLLIVSEHAEH--GRLDQFLID
    ..| .  ... .... |.            ..|.  ..      ..|. |.  |..   |  |  | .. .. . | .| |....  | | ... .
YEILRKIGKGAFGKVYKCRHKK---------TGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKK

RKLNFNNQLTCSDGSNQKVYNFNNGEQERISDDMQALCTLDLLSYGYQIAIAMKFLADSRCLHRALALRSIFVTRNKTIRIGEFGLARINARKEYYIMKS
|. . ..                           . .   .  .| |||. |.... . . .|| |    |....  .| |. |||||.      . .  
RGRHGLR---------------------------FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCG

PQLPLAPEVMAPESSEDKKFTE-KSEVRSFAVCLTGIFQLGVPPHEAVNAVYCGQDIERKLPELQYCHPDMYSFLSSCWNFDPEARPTYSKCVE------
    .||||.        ...  |. . |. ..|   .  | || .        | . .|.       |.. .|.. |...||| |||  .. .      
TPWYMAPEVL--------GYGKCKCDWWSCGCILYEMLC-GYPPFP------QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

---FF
   .|
CHPWF
Kinase T01G5.1.AA PDGFR 284-310 40 3.6e-08 21.95 In-house 332-358 (358) Show / Hide 
Range on Protein: 284-310
Range on HMM: 332-358/358
Sequence Identity: 40% (11 aa)

DMYSFLSSCWNFDPEARPTYSKCVEFF
..|.   .||.|||| |||... ..| 
EIYEIMQKCWDFDPEKRPTFQQLCQFL
Kinase T01G5.1.AA Pkinase 282-310 25 0.002153 13.08 Pfam 263-293 (293) Show / Hide 
Range on Protein: 282-310
Range on HMM: 263-293/293
Sequence Identity: 25% (8 aa)

HPDMYSFLSSCWNFDPEARPTYSKCVEF--F
.... .|...|...||. |||   ...   |
SEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase T01G5.1.AA Pkinase 64-118 18 0.073926 7.65 Pfam 36-103 (293) Show / Hide 
Range on Protein: 64-118
Range on HMM: 36-103/293
Sequence Identity: 18% (13 aa)

HQKMIQD-------ELVTLSSLRSHSCILALVGYVREPNMLLIVSEHAEHG----RLDQFLI---DRKL
|.|. .|       |.  . .| .| .|. | ....... . .| |..|.|     |  ..    ....
HEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCF