Gene T21G5.1 (Nematode worm)

T21G5.1

Species: Nematode worm
Alias: T21G5.1x=(tnfn...tmda), aSWK354, CE13888, T21G5.1
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: I:1.46, WormBase Physical Map location: I: 6882367-6884991

Classification

Group: TK
Family: Fer

Sequence

Name Sequence Type Origin Length Description Download
T21G5.1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 258 Kinase domain by global Sugen HMM Fasta, JSON
T21G5.1.AA Protein Genbank 579 None Fasta, JSON

Protein domain

Protein domains of T21G5.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 T21G5.1.AA SH2 77-164 21 5.3e-16 60.41 SMART 1-87 (87) Show / Hide 
Range on Protein: 77-164
Range on HMM: 1-87/87
Sequence Identity: 21% (20 aa)

CQFYHGIIPRVDAELSLRYV----GDYLLRRAEPRENAGGQFLIISVKREAGFVHVPISQDKEGAKQFYFMP--TLKENTVLDLIDVHLARAQP
...||| |.| .||  |. .    ||.|.|  |.      .....||. . .. |  | ....  ...|.      | ... .|.. .   ...
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES----NPGDYVLSVRWKGKVKHYRIRRNDD--GKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 T21G5.1.AA SH2 79-158 22 2.3e-09 29.3 Pfam 1-81 (81) Show / Hide 
Range on Protein: 79-158
Range on HMM: 1-81/81
Sequence Identity: 22% (20 aa)

FYHGIIPRVDAELSLRY----VGDYLLRRAEPRENAGGQFLIISVKREA---GFVHVPISQDKEGAKQFYFMPTLKENTVLDLIDVH
.||| |.| .||  |.      |..|.|  |  ..       .||...     . |  | ....|  ..| .   | ... .|.. .
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGD----YTLSVRDDGPGDRVKHYRIQRTDNG--GYYITGRHKFCSLQELVEHY
Kinase T21G5.1.AA Fer 290-511 42 7.6e-121 407.77 In-house 44-283 (283) Show / Hide 
Range on Protein: 290-511
Range on HMM: 44-283/283
Sequence Identity: 42% (103 aa)

ATEATMDAKLRFMKEARMMLKNYKHKHIVMIFGIATLNSPLLILMELCPNGSLISYLRKNKGK-VTLLEKLRFSAEASSGLAYLEKMECIHRDIAARNCL
.. ||.. . .||.|||.|..||.|...|...|....  |..|.||.|..||| |||.|||.| |.. ||.|....|..|..||... ||||||||||||
CEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYLKKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCL

LSA-KNEIK--ISDLGLADD-KGMVIDYS----LDKLPIKWLAPEIMQDKVYSLKSDIWAFGIMIWEIFAEGDEPYPG------LNNT--QARAKIVVLD
... |...|  ||| |.... .... ||.    ..|.||.||||| .|...|| |.|.|.||.|.||||. |.|||||      ..|.  |||..|.. .
YHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKG

YRMKFPDEAPTELVQVID-TCWKKDPDMRQTMVLHSSALQ
|.|..|...|.|..|... .||.|||..| ||  .   | 
YMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
TyrKc T21G5.1.AA TyrKc 189-510 28 1.6e-100 341.15 SMART 1-280 (280) Show / Hide 
Range on Protein: 189-510
Range on HMM: 1-280/280
Sequence Identity: 28% (100 aa)

VILYRKIGSGAFGEVFLARMVDPTSEYVLDCAVKKLKQADSQTLTNFNILNFLVIVFWGCSRYFDVHFSISSITMKSHFHTTKKSFASMNRADIFFYFEV
. | .|.|.||||||.....        ...|||.||                                                               
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA------------------------------------------------------------

SATEATMDAKLRFMKEARMMLKNY-KHKHIVMIFGIATLN-------SPLLILMELCPNGSLISYLRKNKGKVTLLEKLRFSAEASSGLAYLEKMECIHR
         .  ||.|||.| | . .|..|| ..|..|          ||.|.||..|.|.| .||||...|... ..| |.  ...| .||... ||||
---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHR

DIAARNCLLSAKNEIKISDLGLADDKGMV-------IDYS-----LDK--LPIKWLAPEIMQDKVYSLKSDIWAFGIMIWEIFAEGDEPYPG-----LNN
|.||||||..... .|||| ||. | .           |.       |  |||.|.||| ....... |||.|.||...||||  |..||||     ..|
DLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSN

TQARAKIVVLDYRMKFPDE--------APTELVQVIDTCWKKDPDMRQTMVLHSSAL
.......    |||. |..        .|.|. |.. .||. ||..| |.    . .
QEVIEYVKQ-GYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase T21G5.1.AA Pkinase_Tyr 292-500 39 3e-81 275.79 Pfam 38-260 (270) Show / Hide 
Range on Protein: 292-500
Range on HMM: 38-260/270
Sequence Identity: 39% (89 aa)

EATMDA---KLRFMKEARMMLKNY-KHKHIVMIFGIAT-LNSP--LLILMELCPNGSLISYLRKN---KGKVTLLEKLRFSAEASSGLAYLEKMECIHRD
| .|.    .  ||.||..| |.. .|..||   |. |    |  ..| ||..|.|.| .||||.   |...|. ..| .... ..|..||| . |||||
EGAMHEQNCREDFMREAKIM-KQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRD

IAARNCLLSAKNEIKISDLGLADDKGMVIDYS-----LDKLPIKWLAPEIMQDKVYSLKSDIWAFGIMIWEIFAEGDEP-YPGLNNTQARAKIVVLDYRM
.||||||.. .| .||.| ||| |  .  ||        ||||||.||| ....... |||.|.||. .||||  |..| |||. |..  ..|    |||
LAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRM

KFPDEAPTELVQVIDTCWKKDPDMR
. |. .| |. ...  ||..||..|
PCPENCPDEIYDLMKQCWHYDPEDR
Kinase T21G5.1.AA TK 299-510 20 1.1e-76 256.38 In-house 86-486 (486) Show / Hide 
Range on Protein: 299-510
Range on HMM: 86-486/486
Sequence Identity: 20% (83 aa)

LRFMKEARMMLK-NYKHKHIVMIFGIATLN------------SPLLILMELCPNGS----LISYLRKNKGK-----------------------------
|... |. ||.   ..|..|| ..|. | .             |..|.||..|.|.    | .||||...|                             
LEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDIT

----------------------------------------------VTLLEKLRFSAEASSGLAYLEKM------ECIHRDIAARNCLLSAKNE------
                                              .|. ..| ... ...|..||...       ..|||.||||||.. .|       
YSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFD

-----IKISDLG--------LADDKGMVIDYS---------------------------LDKLPIKWLAPEIMQDKV---------YSLKSDIWAFGIMI
     .||.| |        || | .   ||                             .||||.|.||| ..|.|         .. |||.|.||...
GCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLM

WEIFAEGDEPYPG-LNN---------TQARAKIVVL-------------DYRMKFPDEAP--------------TELVQVIDTCWKKDPDMRQTMVLHSS
||||  |.|||.| ..|         ..   ...                .||. |. .|              .|. ...  ||..||. | |.    .
WEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHE

AL
.|
QL
Kinase T21G5.1.AA UTK 296-509 28 1.5e-64 219.72 In-house 45-296 (296) Show / Hide 
Range on Protein: 296-509
Range on HMM: 45-296/296
Sequence Identity: 28% (73 aa)

DAKL---RFMKEAR---MMLKNYKHKHIVMIFGIATLNSPLLILMELCPNGSLISYLRKNKG-------KVTLLEKLRFSAEASSGLAYLEKMECIHRDI
...    .||.|||   || . . | ...   |. |  .|..|..|...||.|.||||...         .|| ..| ...  ..|..||. . ..|||.
QEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDL

AARNCLLSAK-------NEIKISDLG---LADDKG------------MVIDYSLDKLPIKWLAPEIMQDK-VYSLKSDIWAFGIMIWEIFAEGDEPYPGL
||||||. .        . .||.|.|   .. . .            ..   . |..||.| |||.. .   ...|||.|.||.  |||.. |  ||||.
AARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGM

NNTQARAKIVVLD-YRMKFPDEAPTELVQVIDTCWKKDPDMRQTMV-LHSSA
.| |. . ..  . |||. |.. | .. ..   ||..||..| ... | .  
SNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase T21G5.1.AA TK-Unique 298-500 29 2.5e-57 196.23 In-house 47-284 (294) Show / Hide 
Range on Protein: 298-500
Range on HMM: 47-284/294
Sequence Identity: 29% (71 aa)

KLRFMKEARMMLKNYKHKHIVMIFGIATLNS-PLLILMELCPNGSLISYLRKNKGK-------------------------VTLLEKLRFSAEASSGLAY
|  |.||..|| .  .|..||...|. | .. | .|.|| ||.|.| .|||.....                         ...   ..|  .  .|..|
KQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEY

LEK--MECIHRDIAARNCLLSAKNEIKISDLGLAD--DKGMVIDYSL--DKLPIKWLAPEIMQ--DKVY-SLKSDIWAFGIMIWEIFAEGDEPYPGLNNT
|..  ....|||..|||.||. ....||.|.|.|.  ... |.. .    ..||.|.|||...  ...| . |||.|.||. .||||  |  ||||. ..
LASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWK

QARAKIVVLDYRMKFPDEA-PTELVQVIDTCWKKDPDMR
. . . .   |||. |..  . |. ... .||...|..|
D-IMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEER
Kinase T21G5.1.AA Src 301-500 37 4.8e-52 175.09 In-house 41-245 (255) Show / Hide 
Range on Protein: 301-500
Range on HMM: 41-245/255
Sequence Identity: 37% (78 aa)

FMKEARMMLKNYKHKHIVMIFGIATLNSPLLILMELCPNGSLISYLR-KNKGK-VTLLEKLRFSAEASSGLAYLEKMECIHRDIAARNCLLSAKNEIKIS
| .||  | |. .|...| .. . .   | .|  |.  .|||  ||. . .|. . | . . ..|  ..| ||||.|  |||| |||| | . .|  |. 
FLQEAQIM-KKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVA

DLGLADDKGMVI--D--Y---SLDKLPIKWLAPEIMQDKVYSLKSDIWAFGIMIWEIFAEGDEPYPGLNNTQARAKIVVLDYRMKFPDEAPTELVQ-VID
| |||    ..   |  |   .  |.|||| |||  .  ... ||| | ||| ..||.  |  |||| .| ..  . |   |||  |.. | || . .. 
DFGLAR---LIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEV-LQQVERGYRMPCPHNCPDELYEQIML

TCWKKDPDMR
 ||.|||. |
QCWHKDPEQR
Kinase T21G5.1.AA SFK-Src 301-500 34 6.3e-52 151.86 In-house 41-245 (259) Show / Hide 
Range on Protein: 301-500
Range on HMM: 41-245/259
Sequence Identity: 34% (72 aa)

FMKEARMMLKNYKHKHIVMIFGIATLNSPLLILMELCPNGSLISYLRKNKGKVTLLEKL-RFSAEASSGLAYLEKMECIHRDIAARNCLLSAKNEIKISD
|..|| .| |  .|   .  . . |   |. |  ||. .|||  ||.  .|.   . .|    |.  .|.||||    .||| |||| |    | .|. |
FLQEAQVM-KKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGD

LGLA---DDKGM-VIDYSLDKLPIKWLAPEIMQDKVYSLKSDIWAFGIMIWEIFAEGDEPYPGLNNTQARAKIVV-LDYRMKFPDEAPTELVQVIDTCWK
 |..    ..        . | |||| ||| |.   .| |||.|.|||.. ||   |  ||||. |     .. .   |||  |   | |. ..   ||.
FGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQ

KDPDMR
. || |
HEPDDR
Kinase T21G5.1.AA Abl 301-510 35 2.8e-49 162.28 In-house 42-252 (252) Show / Hide 
Range on Protein: 301-510
Range on HMM: 42-252/252
Sequence Identity: 35% (75 aa)

FMKEARMMLKNYKHKHIVMIFGIATLNSPLLILMELCPNGSLISYLRK-NKGKVTLLEKLRFSAEASSGLAYLEKMECIHRDIAARNCLLSAKNEIKISD
|.||| .| |. ||. .| . |. |  .|  |. |  ..| |. |||. .. ... .  |   .  .||. |||| . ||||.||||||.. .. .|. |
FLKEAAIM-KEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVAD

LGLAD--DKGMVIDYSLDKLPIKWLAPEIMQDKVYSLKSDIWAFGIMIWEIFAEGDEPYPGLNNTQARAKIVVLDYRMKFPDEAPTELVQVIDTCWKKDP
 |||    . .       | |||| ||| .  . .| |||.||||...|||   |  ||||.. ..   |.   .|||  |.  |..  ...  ||. ..
FGLARMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPYPGIDLSHVYHKLEK-GYRMERPEGCPPKVYELMRQCWQWSH

DMRQTMVLHSSAL
  | .      |.
TDRPSFKEIHHAM
Kinase T21G5.1.AA Frk 294-514 34 2.2e-48 165.69 In-house 35-260 (260) Show / Hide 
Range on Protein: 294-514
Range on HMM: 35-260/260
Sequence Identity: 34% (79 aa)

TMDAKLRFMKEARMMLKNYKHKHIVMIFGIATLNSPLLILMELCPNGSLISYLR--KNKG-KVTLLEKLRFSAEASSGLAYLEKMECIHRDIAARNCLLS
||| .  |..||..| |. .|  .. .. . |.. |..|. ||  .|||  ||.  ..|| .. . . .  .|   .|.||||..  ||||.|||| |. 
TMDPN-DFLREAQIM-KKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVG

AKNEIKISDLGLAD-----DKGMVIDYSLDKLPIKWLAPEIMQDKVYSLKSDIWAFGIMIWEIFAEGDEPYPGLNNTQARAKIVVLDYRMKFPDEAPTEL
 .| .|| | |||      .. .       ..|||| ||| .. . ...|||.|.|||.. ||   |  ||||. | .   ..|  .|||  | . | .|
EHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGRMPYPGMTNAEV-LQMVDHGYRMPQPPNCPQQL

VQVIDTCWKKDPDMRQTMVLHSSALQLLY
 ...  ||..||. | |       |.  .
YEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase T21G5.1.AA Tec 301-500 33 1.4e-46 160.73 In-house 41-242 (254) Show / Hide 
Range on Protein: 301-500
Range on HMM: 41-242/254
Sequence Identity: 33% (69 aa)

FMKEARMMLKNYKHKHIVMIFGIATLNSPLLILMELCPNGSLISYLRKNKGKVTLLE--KLRFSAEASSGLAYLEKMECIHRDIAARNCLLSAKNEIKIS
|. ||. | |   |   |  .|. .   |. |  |   .|.| .|||..|..        |    . . | ||||.   |||| |||||| . .. .|.|
FIEEAKVMMK-LSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVS

DLGLA----DDKGMVIDYSL-DKLPIKWLAPEIMQDKVYSLKSDIWAFGIMIWEIFAEGDEPYPGLNNTQARAKIVVLDYRMKFPDEAPTELVQVIDTCW
| |..    ||       |   | |.|| .||...   || |||.||||.  ||.| .|  ||. . |..   ..    .|.  |. ..... |.   ||
DFGMTRYVLDDQYTS---SVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQG-HRLYRPHLCSMHIYQIMYHCW

KKDPDMR
.  |. |
HEKPEER
Kinase T21G5.1.AA SrcB 301-511 36 7e-45 149.7 In-house 41-251 (251) Show / Hide 
Range on Protein: 301-511
Range on HMM: 41-251/251
Sequence Identity: 36% (79 aa)

FMKEARMMLKNYKHKHIVMIFGIATLNSPLLILMELCPNGSLISYLRKNKGKVTLLEKL-RFSAEASSGLAYLEKMECIHRDIAARNCLLSAKNEIKISD
|..|| .| |. .|...| .. . |   |. |. |   .|.|. .|. ..|    |.||  .||  . |.||.|.|  ||||. | | | |.    || |
FLAEANVM-KTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLIDMSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIAD

LGLADDKGMVIDY------SLDKLPIKWLAPEIMQDKVYSLKSDIWAFGIMIWEIFAEGDEPYPGLNNTQARAKIVVLDYRMKFPDEAPTELVQVIDTCW
 |||     .|.          | |||| ||| ..  .. .|||.|.|||.. ||   |  ||||  | .   . .   |||  ||. | || ...  ||
FGLA----RIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYPGMTNPEV-IRNLERGYRMPRPDNCPEELYNIMMMCW

KKDPDMRQTMVLHSSALQ
|. |. | |     | |.
KERPEERPTFDYLQSVLD
S_TKc T21G5.1.AA S_TKc 189-510 19 1.6e-34 121.91 SMART 1-231 (231) Show / Hide 
Range on Protein: 189-510
Range on HMM: 1-231/231
Sequence Identity: 19% (65 aa)

VILYRKIGSGAFGEVFLARMVDPTSEYVLDCAVKKLKQADSQTLTNFNILNFLVIVFWGCSRYFDVHFSISSITMKSHFHTTKKSFASMNRADIFFYFEV
  . ||||.||||.|...| ..        .|.|..|                                                               
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK---------------------------------------------------------------

SATEATMDAKLRFMKEARMMLKNYKHKHIVMIFGIATLNSPLLILMELCPN--GSLISYLRKNKGK-----VTLLEKLRFSAEASSGLAYLEKMECIHRD
           ....| ... |  .|..|| ....    . | . ||.|..  |.| .|..|....      .  .  .. ..  ..|.|. ..  ||||
----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRD

IAARNCLLSAKNEIKISDLGLADDKGMVIDYSLDKLPIKWLAPEIMQDKVYSL-KSDIWAFGIMIWEIFAEGDEPYPGLNNTQARAKIVVLDYRMKFPDE
.   | ||.   .|||.| |||         .       ..|||..    |.  |.|.|..|....| .. |  |.|   . |.  |...          
LKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP---QMQMMFKKIG----------

APTELVQVIDTCWKKDPDMRQTM-VLH-------SSAL
 . |. . |. |..|||. | |  .|.          .
-SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase T21G5.1.AA Pkinase 308-403 27 2.6e-13 48.12 Pfam 53-159 (293) Show / Hide 
Range on Protein: 308-403
Range on HMM: 53-159/293
Sequence Identity: 27% (29 aa)

MLKNYKHKHIVMIFGIATLNSPLLILMELCPNG----SLISYLR-KNKGKV--TLLEKLRFSAEASSGLAYLEKMECIHRDIAARNCLLSAKNEI----K
..|. .|..|| .... . .. . . ||.|..|    .| .|.. ...|..  .  |  ..  .  .||.|. .| .||||.   |.|.. ...|    |
IMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVK

ISDLGLA
|.| |||
ICDFGLA
Kinase T21G5.1.AA Fer 189-231 32 3e-13 41.56 In-house 1-49 (283) Show / Hide 
Range on Protein: 189-231
Range on HMM: 1-49/283
Sequence Identity: 32% (16 aa)

VILYRKIGSGAFGEVFLAR-----MVDPTSE-YVLDCAVKKLKQADSQT
|.|  |.|.||||||...|     . . ... . ....|||.|..|...
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATK
Kinase T21G5.1.AA Pkinase 421-500 21 1.8e-10 38.08 Pfam 177-281 (293) Show / Hide 
Range on Protein: 421-500
Range on HMM: 177-281/293
Sequence Identity: 21% (23 aa)

WLAPEIMQ-DKVYSLKSDIWAFGIMIWEIFAEGDEPYPGL----NNTQARAKIV-VLDYRMKFPDEAP---------------------TELVQVIDTCW
..|||. . .. |. |.|.|..|....| .  |  |.||     |    ...|. ... . .|. . .                      |. ..|. |.
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

KKDPDMR
.|||  |
CKDPKKR
Kinase T21G5.1.AA Pkinase_Tyr 189-235 28 2.9e-10 35.41 Pfam 1-50 (270) Show / Hide 
Range on Protein: 189-235
Range on HMM: 1-50/270
Sequence Identity: 28% (14 aa)

VILYRKIGSGAFGEVFLARMVDPTSEYVLDCAVKKLKQADSQT---LTNF
... .|.|.||||||..... .  ..  ...|||.||.  ..    .  |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDF
Kinase T21G5.1.AA TK 189-231 20 4.7e-10 29.1 In-house 1-67 (486) Show / Hide 
Range on Protein: 189-231
Range on HMM: 1-67/486
Sequence Identity: 20% (14 aa)

VILYRKIGSGAFG---EVFLARMVDP---------------------TSEYVLDCAVKKLKQADSQT
..| .|.|.|.||   ||..... ..                     ... . ..||| ||  |...
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMS
Kinase T21G5.1.AA UTK 189-231 44 6.3e-10 30.15 In-house 1-45 (296) Show / Hide 
Range on Protein: 189-231
Range on HMM: 1-45/296
Sequence Identity: 44% (20 aa)

VILYRKIGSGAFGEVFLARMVDPT-SEYVLDCAVKKLK-QADSQT
|.| |..|.||||||..|| ....  .|..|.|||...  ||.|.
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQ
Kinase T21G5.1.AA Src 189-206 50 3.2e-05 13.65 In-house 1-18 (255) Show / Hide 
Range on Protein: 189-206
Range on HMM: 1-18/255
Sequence Identity: 50% (9 aa)

VILYRKIGSGAFGEVFLA
. | ||.|.| ||||. .
IKLCRKLGQGQFGEVWMG
Kinase T21G5.1.AA TK-Unique 189-231 28 0.000541 9.8 In-house 1-45 (294) Show / Hide 
Range on Protein: 189-231
Range on HMM: 1-45/294
Sequence Identity: 28% (13 aa)

VILYRKIGSGAFGEVFLARMVDPT--SEYVLDCAVKKLKQADSQT
. . ..||.||||.|. . .. ..  ..     |||.||   ..|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDT
Kinase T21G5.1.AA SFK-Src 189-204 50 0.00073 6.67 In-house 1-16 (259) Show / Hide 
Range on Protein: 189-204
Range on HMM: 1-16/259
Sequence Identity: 50% (8 aa)

VILYRKIGSGAFGEVF
. | .| ||| ||.|.
IRLEKKLGSGQFGDVW
Kinase T21G5.1.AA Pkinase 189-207 47 0.001383 13.76 Pfam 1-19 (293) Show / Hide 
Range on Protein: 189-207
Range on HMM: 1-19/293
Sequence Identity: 47% (9 aa)

VILYRKIGSGAFGEVFLAR
  . ||||||.||.|....
YHIGRKIGSGSFGCVYKCH
Kinase T21G5.1.AA SrcB 189-206 44 0.002864 6.8 In-house 1-18 (251) Show / Hide 
Range on Protein: 189-206
Range on HMM: 1-18/251
Sequence Identity: 44% (8 aa)

VILYRKIGSGAFGEVFLA
. | .|.|.| ||||...
LKLVKKLGAGQFGEVWMG
Kinase T21G5.1.AA Frk 189-204 56 0.00419 6.2 In-house 1-16 (260) Show / Hide 
Range on Protein: 189-204
Range on HMM: 1-16/260
Sequence Identity: 56% (9 aa)

VILYRKIGSGAFGEVF
. | |..||| ||||.
IQLIRRLGSGQFGEVW
Kinase T21G5.1.AA Abl 189-206 33 0.077504 1.34 In-house 1-18 (252) Show / Hide 
Range on Protein: 189-206
Range on HMM: 1-18/252
Sequence Identity: 33% (6 aa)

VILYRKIGSGAFGEVFLA
...  |.| | .|||. .
IMMKHKLGGGQYGEVYEG