W03G9.5

Species: Nematode worm
Alias: W03G9.5, CE14562, aSWK111
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: I:-0.46, WormBase Physical Map location: I: 4970246-4968008

Classification

Group: CK1
Family: TTBKL

Sequence

Name Sequence Type Origin Length Description Download
W03G9.5.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 269 Kinase domain by global Sugen HMM Fasta, JSON
W03G9.5.AA Protein Genbank 488 None Fasta, JSON

Protein domain

Protein domains of W03G9.5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase W03G9.5.AA TTBKL 18-285 37 1.8e-140 472.93 In-house 1-288 (288) Show / Hide
Range on Protein: 18-285
Range on HMM: 1-288/288
Sequence Identity: 37% (109 aa)

YLAFRKLGEGGCGVIYEVAMVKCPGRRFACKAETTV-FDEDPTLPMEHKIISKLNEKNSIHCVELIDKGQSDNYQFIVMTLLGPSLDAIRATLPTNK-FS
... ...||||.|..|.| ..|... ..|.|.| ..  ..| .. ||... .||....|.|. .... |. ..|.|.||||.||.|...|...|..| ||
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

TFSTLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALG--TPKQRLVHVLDFGISRQYLVKDGEN------GGLRIRKPRR---IVPFRGTLRYCSVAA
 ......||| |...|..||.||.||||||.|...|. .  ....|.|...|||..|||..||||.      .....|.||.    .|||||.||||...
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM

QERKEQGRHDDLWSLFYMIVEFVKGSLPWTGIM-EEEKVIVMKEDVTELFNG-------LESECAMFAQHLSVLRYQTNPDYALLRDLL
..||||||||||||..|||.|...| ||||... ..| . ..|.  .|....       ..||...|..||. |||.  |||  .. ..
HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF

Kinase W03G9.5.AA CK1 18-281 30 4.8e-106 358.61 In-house 1-339 (339) Show / Hide
Range on Protein: 18-281
Range on HMM: 1-339/339
Sequence Identity: 30% (102 aa)

YLAFRKLGEGGCG-VIYEV-----AMVKCPG----RRFACKAETTV-FDEDPTLPMEHKIISKLN------------------EKNSIHCVELIDKGQSD
.   .|.||||.|  ||.|       .|...     ..|.|.|     . .|.| .|.... ||.                   ... |.. ....|  |
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

NYQ-FIVMTLLGPSLDAIRA--TLPTNKFSTFSTLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALG-----------TPKQRLVHVLDFGISR-QYL
.|  ..|||||||.|. .|.  .....|||  ..|  .|| |......||.||.|||.||.||..|. .            .. | |...|||..| .|.
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR

VKDGEN-------GGLRIRKPRR---IVPFRG-TLRYCSVAAQERKEQGRHDDLWSLFYMIVEFVKGS--LPWTGIMEEEK-----VIVMKEDVTEL--F
 |||.|       .  ..| ||.    ..||| |.||||......|||||.|||||.|||..|..||.  |||... .|.|     |..||.. .    .
DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM

NG------------LESECAMFAQHLSVLRYQTNPDYALL
.             . .|  ....... |.|.. |||. .
STPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI

Kinase W03G9.5.AA TTBK 18-281 40 7.8e-73 248.28 In-house 1-257 (257) Show / Hide
Range on Protein: 18-281
Range on HMM: 1-257/257
Sequence Identity: 40% (107 aa)

YLAFRKLGEGGCGVIYEVAMVKCPGRRFACKAETTVFDEDPTLPMEHKIISKLNEKNSIHCVELIDKGQSDNYQFIVMTLLGPSLDAIRATLPTNKFSTF
    .| | || | |||   .     . | | |  .      | ||  .  ||  ..  |    |  |  |.. ..||.|.| .|   |   |  .||  
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVE-SAQQPKQVLKMEVAVLKKLQGCD--HVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLS

STLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQYLVKDGENGGLRIRKPRRIVPFRGTLRYCSVAAQERKEQGRHDDLW
.|| .|.| |.||..||..|| |||.|| |||.| .   . | .  ||||  |||.   ||     .| ||    |||| || |. |   .| |||||||
TTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPS-TCRKCYMLDFGLARQYTNACGE-----VRPPREVAGFRGTVRYASINAHRNREMGRHDDLW

SLFYMIVEFVKGSLPWTGIMEEEKVIVMKE--DVTELFNGLESECAMFAQHLSVLRYQTNPDYALL
||||| ||||.| |||  |   ..|  |||  |   | . . .|  .| .|...| |.. |||.|.
SLFYMLVEFVQGQLPWRKIKDKDQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI

Kinase W03G9.5.AA Worm6 18-281 32 6.8e-72 245.15 In-house 1-279 (279) Show / Hide
Range on Protein: 18-281
Range on HMM: 1-279/279
Sequence Identity: 32% (91 aa)

YLAFRKLGEGGCGVIYEVAMVKCPGR-RFACKAETT-VFDEDPTLPMEHKIISKLNEKNSIHCVELIDKGQSDN--YQFIVMTLLGPSLDAIRATLPTNK
.   .|.||||.| .|.|   .     .||.|.|      . . |.||. .  ... ... | ....|.|. ||  . .|||||.|..|  .|...|..|
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK

FSTFSTLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGA---LGTPKQRLVHVLDFGISR--QYLVKDGENGGLRIRKPR-RIVPFRGTLRYCSVAAQER
||   .|  .|| |..| . | .||.||||||.||.||        ... .  ||||..|  .|. |..|     .|.||   ..||||.||...|.  .
FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNE-----LRTPRWTACGFRGTVRYAPLACHKG

KEQGRHDDLWSLFYMIVEFVKGSLPWTGIMEEEKVIVMKEDV---------TELFNGLES-ECAMFAQHLSVLRYQTNPDYALL
.||.| ||. | |||.||...| ||| .. ..  | . |.           ...|..    |     . .  ..|.. |||. .
QEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI

Kinase W03G9.5.AA CK1-Unique 18-233 28 3e-35 119.65 In-house 1-232 (337) Show / Hide
Range on Protein: 18-233
Range on HMM: 1-232/337
Sequence Identity: 28% (67 aa)

YLAFRKLGEGGCGVIYEVAMVKCP-----GRRFACKAETTVFDED----PTLPMEHKIISKLN--EKNSIHCVELIDKGQSDNYQFIVMTLLGPSLDAIR
.  . ..| || |  ..|  |. .       ... | |             .  . | |.|.   .| . |  |..| .|.. . .||||..|||.. ..
WCVIKHIGYGGYGCVHRVIFVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDFHQHRDWWWIVMTMHGPSMEECC

ATLPTNKFSTFS------TLV-MGIQALDSIKEIHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQ--YLVKDGENGGLRIRKPRRIVPFRGTL
  .   .| | .      ... .| | |. |   |  || ||. ||.|.  .|    .|.   .||.||.|    ... ..     ||.|| |.||||..
MMMKNFQF-TLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQ-----IRQPRPITPFRGCK

RYCSVAAQERKEQGRHDDLWSLFYMIVEFVKGS--LPW
.||. .  . .|.|| ||. |.|||..  | .   | |
DYCPCSCHQCREHGRRDDMESWFYMLYHLVHNTRGLSW

Kinase W03G9.5.AA CK1-D 18-281 31 1.3e-31 108.78 In-house 1-261 (261) Show / Hide
Range on Protein: 18-281
Range on HMM: 1-261/261
Sequence Identity: 31% (86 aa)

YLAFRKLGEGGCGVIYEVAMVKCPGRRFACKAETTVFDEDPTLPMEHKIISKLNEKNSIHCVELIDKGQSDNYQFIVMTLLGPSLDAIRATLPTNKFSTF
|   ||.| |  | ||  . ..  .   | | | ..  . | | .| |.   ..    |  .  .  ||  .|  .|| ||||||. .       |||  
YRIGRKIGSGSFGDIYHGTNIQT-NEEVAIKLE-CIKTKHPQLHIESKFYKMMQGGIGIPEIRWC--GQEGDYNVMVMDLLGPSLEDL-FNYCHRKFSLK

STLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQYLVKDGE-NGGLRIRKPRRIVPFRGTLRYCSVAAQERKEQGRHDDL
  |... | .  |. ||   |.|||.|| || .| ||  .  .|...|||....|  .| .    .  |  . .    || || |.      || | |||
TVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMG-LGK-RGNMVYIIDFGLAKRY--RDARTHQHIPYRENKNLT---GTARYASINTHQGIEQSRRDDL

WSLFYMIVEFVKGSLPWTGIMEEEK-----VIV---MKEDVTELFNGLESECAMFAQHLSVLRYQTNPDYALL
 || |... | .||||| |.    |      |.   |.  . .| .|. || . .  .   |...  |||. |
ESLGYVLMYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL

Kinase W03G9.5.AA Dual 77-223 36 1.9e-31 102.89 In-house 71-213 (282) Show / Hide
Range on Protein: 77-223
Range on HMM: 71-213/282
Sequence Identity: 36% (55 aa)

HCVELIDKG--QSDNYQFIVMTLLGPSLDAIRATLPTNKFSTFSTLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQYLV
. .|..| |  . |   ..|| . ||||. ||     . .|.    . .|| |..|.  | ||..||..|||||..| ||  .   |  .||.| | |. 
CFIEFVDYGKCEQDKCKYWVMSPYGPSLQEIRRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCG-LGM-DETTVYMQDFRIVRKYI-

KDGENGGLRIRKPRRIVPFRGTLRYCSVAAQERKEQGRHDDLWSLFYMI
 | ||.  |.  .|  | . |..|| . | .  |.||| ||| .  ||.
-DPENKKHRT--ARKKVKMYGCGRYACRACMMQKDQGRKDDLECWIYMV

Kinase W03G9.5.AA CK1-A 18-281 29 3.4e-31 107.4 In-house 1-261 (261) Show / Hide
Range on Protein: 18-281
Range on HMM: 1-261/261
Sequence Identity: 29% (81 aa)

YLAFRKLGEGGCGVIYEVAMVKCPGRRFACKAETTVFDEDPTLPMEHKIISKLNEKNSIHCVELIDKGQSDNYQFIVMTLLGPSLDAIRATLPTNKFSTF
|   ||.| |  | || ...    |   | | |       | |  | |.   |.    |  ..    |.  .|  .|| ||||||. .   . . .|.  
YRLVRKIGSGSFGDIY-LGINITNGEEVAIKMESNKA-RHPQLIYEAKVYRILQGCVGIPHMRWY--GCEKDYNVMVMDLLGPSLEDL-FNFCKRRFTMK

STLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQYLVKDGENGGLRIRKPRRIVPFRGTLRYCSVAAQERKEQGRHDDLW
  |..  | .  |  .|  .|.|||.|| || .| .|    .| ...|||....|  .  .   .  |. . ..   || || |. |.   || | ||. 
TVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMG-IGRHCNKL-FLIDFGLAKKYRDSRTRQ-HIPYREDKNLT---GTARYASINAHLGIEQSRRDDME

SLFYMIVEFVKGSLPWTGIMEE------EKVI--VMKEDVTELFNGLESECAMFAQHLSVLRYQTNPDYALL
|. |... | .|.||| |.         ||.    |   . .|  |  .| .|. ..   ||.. .|||  |
SMGYVMMYFNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL

Kinase W03G9.5.AA CK1 18-236 31 1.4e-29 99.06 In-house 1-219 (271) Show / Hide
Range on Protein: 18-236
Range on HMM: 1-219/271
Sequence Identity: 31% (74 aa)

YLAFRKLGEGGCGVIYEVAMVKCPGRR--FACKAETTVFDEDPTLPMEHKIISKLNE---KN-SIHCVELIDKGQS--DNYQFIVMTLLGPSLDAIRATL
|   ||.|.|  |.||..  .   | .   |.| |       | |. | ||   |.     | ...   ..  ||    .| ..||.||||||.     .
YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSK-HPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDL-FNF

PTNKFSTFSTLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQYLVKDGENGGLRIRKPRRIVPFR------GTLRYCSVA
   |||   .|  . | .. |  .|  .|.|||.|| || .|  .  ..  |.. |||.. .|.            | .. .|.|      || || |. 
CNRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGR-YGKHCHQVYIIDFGLAKRYR----------DDKTHQHIPYRENKNLTGTARYASIN

AQERKEQGRHDDLWSLFYMIVEFVKGSLPWTGI
.   .||.| ||. || |... | .||||| |.
THLGIEQSRRDDMESLGYVLMYFLRGSLPWQGL

Kinase W03G9.5.AA CK1-Unclassified 18-178 31 1.3e-22 63.53 In-house 1-166 (244) Show / Hide
Range on Protein: 18-178
Range on HMM: 1-166/244
Sequence Identity: 31% (54 aa)

YLAFRKLGEGGCGVIYEVAMVKCPGRRFACKAETTVFDEDPTLPMEHKIISKLNEKNSI-----HCVELIDKGQSDN--YQFIVMTLLGPSLDAIRATLP
|   .|.| |  | ||..  ..   . .|.| | .     |.|. | ||   |.   ..     .   ..  || ..  |...||.||||||. .     
YRVIEKIGQGSFGEIYKCINMQTN-EEVAIKLEKKNSK-HPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMC-

TN-KFSTFSTLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQYL-V-KDGE
 | |||   .|  . | .. |  .|  .|.||| || || .| ||  ..  |.  |||.|  |.   |.|.
-NRKFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGK-NHHQVYIIDFGLSKRYIDMDKTGK

Kinase W03G9.5.AA S_TKc 18-303 17 1.9e-13 20.17 SMART 1-231 (231) Show / Hide
Range on Protein: 18-303
Range on HMM: 1-231/231
Sequence Identity: 17% (54 aa)

YLAFRKLGEGGCGVIYEVAMVKCPGRRFACKAETTVFDEDPTLPMEHKIISKLNEKNSIHCVELIDKGQSDNYQFIVMTLLGP---SLDAIRATLPTNK-
|   ||.|.|. |. | .  .|  ||..|.|          ..  | .| .|    .  . | |.|  |. .. ..|| ...    .|  .    .... 
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSTFSTLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQYLVKDGENGGLRIRKPRRIVPFRGTLRYCS--VAAQERK
   |.   .  .  | .. .. .|. |..|||.||.|  .          . . |||..||.                    | ||. |..  |      
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL------------------TTFCGTPWYMAPEVL-----

EQGR-HDDLWSLFYMIVEFVKGSLPWTGIMEEEKVIVMKEDVTELFNGLESECAMFAQHLSVLRYQTNPDYALLRDLLM-NIFVRRNFNAQMK-------
  |.   | ||.  .. |.. |  |.   |..   ...                            . .   ..| .|  .   |      ..       
GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG----------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC

VDWE
  | 
HPWF

Kinase W03G9.5.AA CK1-Unclassified 195-241 51 1e-10 27.89 In-house 178-224 (244) Show / Hide
Range on Protein: 195-241
Range on HMM: 178-224/244
Sequence Identity: 51% (24 aa)

GTLRYCSVAAQERKEQGRHDDLWSLFYMIVEFVKGSLPWTGIMEEEK
|| || |. |   .||.| ||| || | .. | |||||| .|  ..|
GTARYASINAHLGIEQSRRDDLESLGYVLIYFLKGSLPWQNIKANNK

Kinase W03G9.5.AA Pkinase 133-246 23 4.5e-08 29.64 Pfam 124-230 (293) Show / Hide
Range on Protein: 133-246
Range on HMM: 124-230/293
Sequence Identity: 23% (28 aa)

IHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQYLVKDGENGGLRIRKPRRIVPFRGTLRYCSVAA-QERKEQGRHDDLWSLFYMIVEFVKGSL
.|. |..|||.||.|. |   |...   |.. |||...|.           . . .    | ||..|..    ..... |.  | ||.  .. |.. | .
CHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFD----------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRP

PWTGI-----MEEEKVIVMK
|. |      ... ..|...
PFPGHCWHDNHDQMQMICRI

Kinase W03G9.5.AA Dual 270-285 37 0.005838 5.64 In-house 267-282 (282) Show / Hide
Range on Protein: 270-285
Range on HMM: 267-282/282
Sequence Identity: 37% (6 aa)

LRYQTNPDYALLRDLL
. |.. |||. .|  |
YQYDSTPDYDYFRNCL

Kinase W03G9.5.AA CK1 249-279 31 0.010325 5.4 In-house 240-271 (271) Show / Hide
Range on Protein: 249-279
Range on HMM: 240-271/271
Sequence Identity: 31% (10 aa)

VTELFNG-LESECAMFAQHLSVLRYQTNPDYA
| .|..| . .| ||. ..   |...  |||.
VEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM