Gene wee-1.3 (Nematode worm)

wee-1.3

Species: Nematode worm
Alias: Y53C12A.1, aSWK259, CE14884, wee-1.3
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: n/a, WormBase Physical Map location: II: 9716373-9713641,

Classification

Group: Other
Family: WEE
Subfamily: Myt1

Sequence

Name Sequence Type Origin Length Description Download
wee-1.3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 248 Kinase domain by global Sugen HMM Fasta, JSON
wee-1.3.AA Protein Genbank 677 None Fasta, JSON

Protein domain

Protein domains of wee-1.3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase wee-1.3.AA WEE 108-355 42 1.1e-152 513.58 In-house 1-297 (297) Show / Hide 
Range on Protein: 108-355
Range on HMM: 1-297/297
Sequence Identity: 42% (125 aa)

FQIDEIIGRGSFGEVFAARCREDSQLYAVKVSLAPIRQHS--ISKYREAESHMIIP------PHKNLVKFYRAWEETGRLYIQTELCDQS------LLKY
||... ||.||||||...|||.|...||.|.| .|.|..|   ...||...|| ..      .|.. |..|.||||....|||.|.|...      ....
FQEVQKIGEGSFGEVYKCRCRIDGCIYAIKKSKQPFRGYSERKRALREVYAHMVLGQIMDCDHHPHIVRYYSAWEEDDHMYIQMEYCNGGSNLLQFWIQQ

CT-EKHALPEDEIWNIFVDLLQAVHHLHSN-DMIHDDIKPENIFLTKDM--------------------ICKLGDFGLVINLK-NPNDVKSAEEGDSKYL
|. ..|.|||..||.|.||..|..||.||| .|.|.||||||||..|.|                    .||.||||.|.... |.|......||||.|.
CHNWNHWLPEWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFNMMCKIGDFGHVTDMNSNNNNPHQEQEGDSRYM

APEVLNG--RPTKS--SDIFSLGMTILEATTDLDVPSNGDSWHQIRNG-------QIP-DRFFAGISTDLRSLIALMLDSDPRIRPTSRDLLDHPVI
|||.|.|  ..|..  .||||||.||.|.....|.|.|||.|||||.|       ||| ..|...||..|..||..|.. ||. |||...||.|||.
APEILQGYYHYTHLYKADIFSLGITIYELACNMDLPKNGDWWHQIRQGDLSFDKNQIPFPEFDNIISQELKQLIKWMMHPDPEQRPTCQQLLQHPVL
Kinase wee-1.3.AA S_TKc 108-355 25 2.4e-51 177.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 108-355
Range on HMM: 1-231/231
Sequence Identity: 25% (68 aa)

FQIDEIIGRGSFGEVFAARCREDSQLYAVKVSLAPIRQHSISKYREAESHMIIPPHKNLVKFYRAWEETGRLYIQTELCDQ---SLLKYCTEKHA-----
..| ..||.|.||.|. .| ... ...|.|.         .. .|| . ..    |.|.||.| .... ..||. .|.||.   .|..|  ..       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LPEDEIWNIFVDLLQAVHHLHSNDMIHDDIKPENIFLTKDMICKLGDFGLVINLKNPNDVKSAEEGDSKYLAPEVLNGRPTK-SSDIFSLGMTILEATT
 .|| ... ..  ...|. ..||.  || |.|||||.|..    |..||||   |       .   |   |.|||||    .| ..|. |.| .. |  .
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLC

DLDVPSNGDSWHQIRNGQIPDRFFAGISTDLRSLIALMLDSDPRIRPTSRDLLD-------HPVI
    |   .    ...           | .....|  .|. ||. |||  ..|        || .
-GYPPFP-QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase wee-1.3.AA Pkinase 108-355 22 3e-49 174.72 Pfam 1-293 (293) Show / Hide 
Range on Protein: 108-355
Range on HMM: 1-293/293
Sequence Identity: 22% (66 aa)

FQIDEIIGRGSFGEVFAARCREDSQLYAVKVSLAPIRQHSISKY----REAESHMIIPPHKNLVKFYRAWEETGRLYIQTELCDQ-----SLLKYCT--E
..| ..||.||||.|. .. . .....|||.   . . ..  ..    .|.. .  .  |.| |..|...|. ...|. .|.|.      .|  | .  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

KHAL--PEDEIWNIFVDLLQAVHHLHSNDMIHDDIKPENIFLTKDMIC----KLGDFGLVINL-KNPNDVKSAEEGDSKYLAPEVLN-GRP-TKSSDIFS
. ..  .|.|. ...  .|... ..||.  || |.|||||.. ... .    |..||||   .   .|   .   | . |.||||.. |.. ....|..|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGMTILEATTDLDVPSNGD----------SWHQIRNGQIPDRFFAGIS-------------------TDLRSLIALMLDSDPRIRPTSRDLLDHPVI
.| .. |  .    |  |.             .|. ....  ..  .|                    .....|  .|. ||  ||| ...| || .
CGCILYEMLCGR-PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase wee-1.3.AA STE 108-355 21 2.9e-40 139.89 In-house 1-359 (359) Show / Hide 
Range on Protein: 108-355
Range on HMM: 1-359/359
Sequence Identity: 21% (81 aa)

FQIDEIIGRGSFGEVFAARCR------EDSQL---------YAVK-VSLAPIR----------------QHSISKYREAESHMIIPP-HKNLVKFYRAWE
... |.||.|.||.|. |...      .  ..         .|.| ..| . .                .   .  .| . ..   . |.| ||.| . .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ETG-------RLYIQTELCD-QSLLKYCTEK--------------HALPEDEIWNIFVDLLQA-VHHLHSNDMIHDDIKPENIFLTKDMICKLGDFGLVI
  |        |.|  |..|  || .   .|              | .||..|  | ...|..  ..|||.  || |||| ||.|     .|| |||.  
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

NLKN--------------------PNDVKSAEEGDSKYLAPEVLNGRPTK-------SSDIFSLGMTILE-ATTDLDV---PSNGDSWHQIRN-------
.| .                     | .         . ||||.... ..       ..|| ||| ||.| ||        .     .. ..|       
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-----WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQF

-------GQIP---DRFF---------------AGISTDLRSLIALMLDSDPRIRPTSRDLLD--HPVI
       |..|   |..                   | ...  |.. |. ||. |||. .||   || |
EQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase wee-1.3.AA Ciliate-E2 108-292 20 1.3e-39 133.62 In-house 1-286 (365) Show / Hide 
Range on Protein: 108-292
Range on HMM: 1-286/365
Sequence Identity: 20% (60 aa)

FQIDEIIGRGSFGEVFAARCREDSQLYA----------------VKVSL--APIRQHSISKYREAESHMI--IPP---------------HKNLVKFYRA
. . ..||.|.|| |. .. ... ...|                ||...    | ...  .. . | |..  | .               |.|..|.| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

WE--ETGRLYIQTELCDQ-SLLKYCTEK-----------HALPEDEIWNIFVDLLQ---------------AVHHLHSND-MIHDDIKPENIFLTKDMIC
..   .  .|. .|.|.. .|..|. ..           . . | || .|.  .||               |...|||.   || |||||||..     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLGDFGLVINLKNPNDVKSAEEGDSK--------------------------------YLAPEVLNGRP----------TKSSDIFSLGMTI
|. ||||  .....|. ..     .|                                |.|||.||| .          ....||.|||...
KIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL
Kinase wee-1.3.AA Ciliate-E2-Unclassified 108-355 19 2e-39 134.44 In-house 1-352 (352) Show / Hide 
Range on Protein: 108-355
Range on HMM: 1-352/352
Sequence Identity: 19% (70 aa)

FQIDEIIGRGSFGEVFAARCREDSQLYAVKVSLAPIRQHSISKYR-----------EAESHM---------------IIPPHKNLVKFYRAWEETGRLYI
. | ..||.|.||.|. ...... |.|| |   .   |.  .|.            | ....               .  || ..||.. . . .  .||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMK--YMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

QTELCDQSLLKYCTEK------------------HALPEDEIW-----NIFVDLLQAVHHLHSND-MIHDDIKPENIFLTKDM---ICKLGDFGLVINLK
 .|.|..  |... .|                  . ..| ..      ..|  .||.  .||..   || |||||||......    .|. |||. ....
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

NPNDVKSAEE----------------GDSKYL----APEVLNG-RPT----KSSDIFSLGMTILEATTDLDVPSNGDS-------------------WHQ
..|. .  .                 |   |.    ||||| |  .     ...||.|||. . |  .    | .. .                    .|
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY-YPFYDNNCEQHQQLITQWINNAYRKQLYQ

IRNGQIPDRFF-------AGISTDLRSLIA----LMLDSDPRIRPTSRDLLDHPVI
. . .... .         ..|     .|      ||. .|  |.|  ..| || .
NIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase wee-1.3.AA TKL 114-353 16 6.2e-34 119.06 In-house 1-364 (364) Show / Hide 
Range on Protein: 114-353
Range on HMM: 1-364/364
Sequence Identity: 16% (60 aa)

IGRGSFGEVFAARCREDS--------QLYAVKVSL--------------------------APIRQHSISKYREAESHMIIPPHKNLVKFYRAWEETGR-
||.|.||||. ...|  .        .  |||.                            .|  ..   . .|   .|.   | |.|.|. .  . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LYIQTELC-DQSLLKYCTEKHALPEDEIWNIFVDLLQAVHHLHSND--------MIHDDIKPENIFLTKDMI--------------CK
            |.| .|.|   ||| | .       . . ..  |  .....|||..        .|| |.|..||.. ...               ||
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

LGDFGLVINLKNPND-------------------VKSAEEGDSKYLAPEVLN-----------------GRPTKSSDIFSLGMTILEATTDLDVPSNGDS
..||||  .... ..                    .. . |   ..|||||.                 .  ....|..| |. . |  |   . .. ..
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

W------------HQIRNGQIPDRFF------------AGISTDLRSLIALMLDSDPRIRPTSRDLLDHP
              .. . . .                  . .....|.    |.||. ||.  ..|.. 
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase wee-1.3.AA CAMK 113-289 18 2.4e-31 97.68 In-house 1-321 (425) Show / Hide 
Range on Protein: 113-289
Range on HMM: 1-321/425
Sequence Identity: 18% (60 aa)

IIGRGSFGEVFAARCREDS------------QLYAVKV---SLAPI------------------------RQHSIS-KYREAESHMI---IPP---HKNL
..||||||.|. .. ...             | .|.|.   . ..                         |...    .|| | ..    |     |.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKFYRAWEE-----------TGR---------LYIQT---ELCDQ-----SLLKYCTEK---------------HALPEDEIWNIFVDLLQAVHHLHSND
.|.| ..|            | .         .|. .   |.|.       |. | .|.               . ..|.|   .|  ...|||..||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

MIHDDIKPENIFLTKDM-----------------ICKLGDFGLVINLKNPND------VKSAEEGDSK-------------------YLA-PEVLNG---
 .| |.||||| |....                   |. |||. . ..  ..      .|..|   ..                   | | ||||||   
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH

-----------RP-TKSSDIFSLG
           .. ....|. |.|
CNMQNATDEEKPYYGPKCDMWSCG
Kinase wee-1.3.AA ULK 163-290 26 4.7e-25 84.46 In-house 77-244 (329) Show / Hide 
Range on Protein: 163-290
Range on HMM: 77-244/329
Sequence Identity: 26% (44 aa)

HKNLVKFYRAWEETGR--LYIQTELCDQ-SLLKYCTEKHALPEDE----------IWNIFVDLLQAVHHLHSNDMIHDDIKPENIFLTKD----------
|.| ||.|   |..    .|| .|.|..  | .|  ... ||||.          . ..| ..|..  .||..  || ||||.|| ....          
HPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVH

--MICKLGDFGLVINLKNP---NDVKSAEE------GDSKYLAPEVLNGR-----PT-KSSDIFSLGM
  ...|..|||.   . |.   ...  .        |   | ||..|.|.     .. . .||.|||.
PNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGC
Kinase wee-1.3.AA PEK 179-289 19 2.4e-24 81.11 In-house 358-581 (655) Show / Hide 
Range on Protein: 179-289
Range on HMM: 358-581/655
Sequence Identity: 19% (43 aa)

LYIQTELCDQSLLKYCTEKH---------------------------------------------ALPEDEIWNIFVDLLQAVHHLHSNDMIHDDIKPEN
||||.|.|....|.. .. .                                              ...|..|.|| ..| .. ..||. ||| |.|| |
LYIQMEYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNYIMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSN

IFLTKD-----MICKLGDFGLVIN--------------------------LKNPNDVKSAEEGDSK-------------------------------YLA
|||. |     |. | |||||..|                          ....|  ..  .....                               | .
IFLDCDGQHHQMQVKIGDFGLATNHEMLSQSQKNYNQQDQSYWKYVANDNCQWWNTNQQNSPTGQDTHMWSNNYHIQPTSMFYCEHCHHTGGVGTCLYMS

PEVLNGR------PTKSSDIFSLG
||.|.|.       .. .|..|||
PEQLSGQHYQKSHYNHKVDMYSLG
Kinase wee-1.3.AA NEK 163-249 30 2.5e-24 82.87 In-house 63-169 (286) Show / Hide 
Range on Protein: 163-249
Range on HMM: 63-169/286
Sequence Identity: 30% (33 aa)

HKNLVKFYRAWEETG--RLYIQTELCD-----QSL---LKYCT-EKHALPEDEIWNIFVDLLQAVHHLHSN-----DMIHDDIKPENIFLTK-DM---IC
| | ||.| ...| .  .|.|  | |.     . .   .| .. ... ..|..||..|. .. |....|..       .| |||| |||||| ..   . 
HPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNV

KLGDFGL
|.||||.
KIGDFGI
Kinase wee-1.3.AA ULK 163-290 24 2.1e-22 76.31 In-house 72-240 (324) Show / Hide 
Range on Protein: 163-290
Range on HMM: 72-240/324
Sequence Identity: 24% (42 aa)

HKN--LVKFYRAWEETGR--LYIQTELCDQ-SLLKYCTEKHA---------LPEDEIWNIFVDLLQAVHHLHSNDMIHDDIKPENIFLTKD---------
|.|   ||.|   |..    .|| .|.|..  | .|  ...          |.|.|. ..| .....  .||..  || ||||.|| ....         
HPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKV

---MICKLGDFGLVINLKNP----NDVKSAEE-----GDSKYLAPEVLNGR-----PT-KSSDIFSLGM
    ..|..|||.   . |.    .. ...       |   | ||..|.|.     .. . .||.|||.
HPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGC
Kinase wee-1.3.AA TyrKc 108-359 19 2e-14 10.48 SMART 1-280 (280) Show / Hide 
Range on Protein: 108-359
Range on HMM: 1-280/280
Sequence Identity: 19% (56 aa)

FQIDEIIGRGSFGEVFAARCREDSQLYAVKVSLAPIRQHSISKYREAESHMII-PPHKNLVKFYRAWEET-------GRLYIQTELCDQ-SLLKYCTEKH
 . ....|.| ||||. .. .   .  |||.  .         .|||.  . . . |.|.|..| .  .        . |.| .|...  .|..|  ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

A-LPEDEIWNIFVDLLQAVHHLHSNDMIHDDIKPENIFLTKDMICKLGDFGLVINLKNP-------NDVKSAE--EGDS----KYLAPEVL-NGRPTKSS
  |. ..  .. ..  .   .|||.  || |.   |. .... ..| .||||  ....           ...|   |..    . .|||..  |. |  |
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DIFSLGMTILEATTDLDVPSNG-----DSWHQ----IRNGQIPDRFFAG-------ISTDLRSLIALMLDSDPRIRPTSRDLLDHPVIKKKL
|..| | .. |  |. . |  |      |. .    ...|  ...   .        .... ...    . ||  ||| ...      ....
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI------HECF
Kinase wee-1.3.AA PEK 310-355 25 3e-08 24.03 In-house 604-655 (655) Show / Hide 
Range on Protein: 310-355
Range on HMM: 604-655/655
Sequence Identity: 25% (13 aa)

QIRN------GQIPDRFFAGISTDLRSLIALMLDSDPRIRPTSRDLLDHPVI
..|.      |..|   |.   ......| .||. ||. ||.. ..|.|. .
DLRDESIQFPGDFPPKWFDNKYPKQADFIQWMLSHDPQQRPSAQQILQHEFF
Kinase wee-1.3.AA ULK 108-138 28 3.3e-08 25.29 In-house 1-35 (324) Show / Hide 
Range on Protein: 108-138
Range on HMM: 1-35/324
Sequence Identity: 28% (10 aa)

FQIDEIIGRGSFG-EVFAARCRED---SQLYAVKV
.......| ||||  |. .|. ..    |..|.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKM
Kinase wee-1.3.AA Pkinase_Tyr 108-249 22 1.1e-07 26.69 Pfam 1-157 (270) Show / Hide 
Range on Protein: 108-249
Range on HMM: 1-157/270
Sequence Identity: 22% (36 aa)

FQIDEIIGRGSFGEVFAARCR----EDSQLYAVKVSLAPIRQH---SISKYREAESHMIIPPHKNLVKFYRAWE-ETGR--LYIQTELCDQ-SLLKYCTE
 .... .|.|.||||. ....    .. .  |||.      ..   . .  |||.  . .. |.|.|..| .   . .   .|| .|..   .||.|  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----KHALPEDEIWNIFVDLLQAVHHLHSNDMIHDDIKPENIFLTKDMICKLGDFGL
    |..|.  .. .. ..  ..  .|.|. .|| |.   |. .|.....| .||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL
Kinase wee-1.3.AA NEK 325-355 45 1.3e-07 23.25 In-house 256-286 (286) Show / Hide 
Range on Protein: 325-355
Range on HMM: 256-286/286
Sequence Identity: 45% (14 aa)

STDLRSLIALMLDSDPRIRPTSRDLLDHPVI
|.||..|| .||  ||  ||. ...| .| |
SQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase wee-1.3.AA ULK 108-138 25 1.4e-07 22.6 In-house 1-35 (329) Show / Hide 
Range on Protein: 108-138
Range on HMM: 1-35/329
Sequence Identity: 25% (9 aa)

FQIDEIIGRGSFGEVFAARCRED----SQLYAVKV
.......| |||| |. .|. ..     ...|.|.
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKM
Kinase wee-1.3.AA NEK 108-137 34 4.3e-07 21.45 In-house 1-35 (286) Show / Hide 
Range on Protein: 108-137
Range on HMM: 1-35/286
Sequence Identity: 34% (12 aa)

FQIDEIIGRGSFGEVFAARCREDSQL-----YAVK
..| . ||.||||.|. .|...|..      |. |
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWK
Kinase wee-1.3.AA PEK 108-137 32 9.8e-07 18.66 In-house 1-31 (655) Show / Hide 
Range on Protein: 108-137
Range on HMM: 1-31/655
Sequence Identity: 32% (10 aa)

FQIDEIIGRGSF-GEVFAARCREDSQLYAVK
|.  ...|.| | | |. .. . |...||.|
FEEIQCLGKGGFGGQVYKVQNKLDGCYYAIK
Kinase wee-1.3.AA CAMK 308-355 24 3e-06 15.56 In-house 356-425 (425) Show / Hide 
Range on Protein: 308-355
Range on HMM: 356-425/425
Sequence Identity: 24% (17 aa)

WHQIRNGQI--PDRFFAGIS--------------------TDLRSLIALMLDSDPRIRPTSRDLLDHPVI
...|..|.   |. .| .||                    .. ..||  ||  ||  |.|  . |.|| .
FEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase wee-1.3.AA Ciliate-E2 324-355 32 5.2e-05 13.12 In-house 329-365 (365) Show / Hide 
Range on Protein: 324-355
Range on HMM: 329-365/365
Sequence Identity: 32% (12 aa)

ISTDLRSLIAL----MLDSDPRIRPT-SRDLLDHPVI
.| .   ||      ||. ||  |.|   ..|.|| .
WSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF