Gene Y111B2A.1 (Nematode worm)

Y111B2A.1

Species: Nematode worm
Alias: CE26621, Y111B2A.b, aSWK173, Y111B2A.1
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: III:17.86, WormBase Physical Map location: III: 12490998-12488284

Classification

Group: CMGC
Family: CLK

Sequence

Name Sequence Type Origin Length Description Download
Y111B2A.1.AA Protein Genbank 393 None Fasta, JSON
Y111B2A.1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 265 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of Y111B2A.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Y111B2A.1.AA CLK 50-392 32 1.2e-183 556.18 In-house 1-350 (350) Show / Hide 
Range on Protein: 50-392
Range on HMM: 1-350/350
Sequence Identity: 32% (116 aa)

LENVSVLGEGVFGTVFEVADAEKKKKFALKLFKAGHTQFGCEDWVRESELSIPNYLQIMKSVAAAHHPNLIKLVKSGKM-ASVPEGYLRIAILMELRGKS
.|.|..||||.||.|.|..|....||.................||...        ||||.....|.||........|| .....|...|.|..||.|.|
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEIN--------QIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLS

LFSVMDSTKSEVPNKEISFPIATIREIGAQILSAMKKLEKMEIVHLDLKPENICFTST------CTFTTEIRKD--------VCYISPSEELNVCIIDFG
....|.|..|..|||.|..||..||....|...|.|.|..|...|.|||||||||...      |||.....|.        ||..........|.||||
IYDFMKSNNSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICFVDSRFTHFDCTFKYNHKKKINKKSNNCVCHYWHVKNTHICVIDFG

NARKSNQEDLKSSEVVQTQNYRAPEIFMGLPFSTRSDVWSFGCILSELYTGELLFYGNDEHDTEQLQFELMQLILQQAPSYLMMRKAAENKKKMI---CI
.|.|..... ..|..|.|..|||||...||..|...||||.||||.|||||..||...|...........|.....|...  . |     |.|       
SATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMIQRTRR--FKVKQKYFYHNRL

DGNVYMKKRAKSSFDPPLPLYKQRRRNDRAAIPLFELLERILIFDPTRRLTFSEISSETFF
|... ..  ........ || .... .|  ...||.|....|..||..|.| ..... .||
DWDW-HNSDGRYVMENCKPLKQYMDCKDPEHRQLFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase Y111B2A.1.AA CMGC 50-392 17 9e-61 198.04 In-house 1-513 (513) Show / Hide 
Range on Protein: 50-392
Range on HMM: 1-513/513
Sequence Identity: 17% (91 aa)

LENVSVLGEGVFGTVFEVAD--------------AEKKKKFALKLFKAGHTQFGCEDWVRESEL----------SIPNYLQIMKSVAAA-----------
 |.....||| .|.|..  |               | ... |.| .|        .    | ..          ..   ..|.| .  .           
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIK-------NPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDP

---HHPNLIKLVKSGKMA-SVPEGYL----------RIAILMELRGKSLFSVMDSTKS--------EVPNKE-------------ISFPIATIREIGAQI
   ||.|..||  . .   | ...|            . . .|. ...|. ......         . .  .              .|.|  || .  ||
DNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMI-HIR-YMYQI

LSAMK--KLEKME--IVHLDLKPENICFTSTCTFTTEIRK------DVCYISPSEELNVCIIDFGNARKSNQEDLK---------------------SSE
| ..|   . ..   |.| ||||||| ....|.  |.. .      ..|    ..  .. |.|||.||. .... .                      ..
LRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRM-MWKSEDWNPC----QKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTH

VVQTQNYRAPEIFMGLP----------FSTRSDVWSFGCILSELYTG--------ELLFYGNDE-----------HDTEQLQFELMQLI---LQQ-----
 |.|  |||||| .| .          ..|  |.||.|||. |.|||        . || |..|            |  .. |...  .   .|.     
YVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHF

-----APSYLMMRKAAENKKKM-----------ICIDGNVYMKKRAKSSFDPPLPLYKQRRRNDR--------------------------------AAI
        .  | |  ...|..           .....  | ..  .    || |. ..  ....                                .  
NFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDP

PLFELLERILIFDPTRRLTFSEISSETFF
 ...||...|..||..|.| ... .  .|
QAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase Y111B2A.1.AA S_TKc 50-392 18 2.7e-46 161.02 SMART 1-231 (231) Show / Hide 
Range on Protein: 50-392
Range on HMM: 1-231/231
Sequence Identity: 18% (67 aa)

LENVSVLGEGVFGTVFEVADAEKKKKFALKLFKAGHTQFGCEDWVRESELSIPNYLQIMKSVAAAHHPNLIKLVKSGKMASVPEGYLRIAILMELRGK--
 | . ..|.| ||.|. . . . ....|.|  |                 .| . .||.|.    ||||..||  .           .. . ||. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------EHIRREIQILKK----HHPNIVKLYDVFQD-------DHLYMVMEYCDGDL

-SLFSVMDSTKSEVPNKEISFPIATIREIGAQILSAMKKLEKMEIVHLDLKPENICFTSTCTFTTEIRKDVCYISPSEELNVCIIDFGNARKSNQEDLKS
 .||..... ... ..    ||  ..| . .||..|.. . .. |.| ||||||| ...                     .. |.||| ||.        
GDLFDYIKKRGRHGLR--FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------------------HIKICDFGLARQL-------

SEVVQTQNYRAPEIFMGLPFST-RSDVWSFGCILSELYTGELLFYGNDEHDTEQLQFELMQLILQQAPSYLMMRKAAENKKKMICIDGNVYMKKRAKSSF
. .. | .|.|||..   .... ..|.||.|||| |...|. .|.          .......|.                                    
TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---------QMQMMFKKIG------------------------------------

DPPLPLYKQRRRNDRAAIPLFELLERILIFDPTRRLTFSEISS-------ETFF
                  .. ......| .||..|.|  |.           .|
----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Y111B2A.1.AA Pkinase 50-392 20 1.5e-38 137.44 Pfam 1-293 (293) Show / Hide 
Range on Protein: 50-392
Range on HMM: 1-293/293
Sequence Identity: 20% (73 aa)

LENVSVLGEGVFGTVFEVADAEKKKKFALKLFKAGHTQFGCEDWVRE-SELSIPNYLQIMKSVAAAHHPNLIKLVKSGKMASVPEGYLRIAILMELRGK-
.. ....|.| ||.|..  .    |..|.| .|  |.  ...   |  ||..| . |.         ||| ..|  .           .| . ||. .. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN---------HPNIVRLYDWFED------KDHIYMVMEYCEGG

----SLF----SVMDSTKSEVPNKEISF--PIATIREIGAQILSAMKKLEKMEIVHLDLKPENICFTSTCTFTTEIRKDVCYISPSEELNVCIIDFGNAR
    .||                .. .|  .  ... .  |||.... . .| |.| ||||||| . ....  .                |.|.||| |.
LYVMDLFDYIST----------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA---------------CVKICDFGLAK

KS-NQEDLKSSEVVQTQNYRAPEIFM-GLPFSTRSDVWSFGCILSELYTGELLFYGN----DEHDTEQLQFELMQ--LILQQAPSYLMMRKAAENKKKMI
.  .  .   . .. | .|.|||. . | . ....|.||.|||| |...|...|.|     . ||  |. .. |.  |  .   .. ...    .  .  
QFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H

CIDGNVYMKKRAKSSFDPPLPLYKQRRRNDRAAIPLFELLERILIFDPTRRLTFSEISSETFF
                         ... ...  .. ......| .||..|.|. .|    .|
----------------------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase Y111B2A.1.AA Ciliate-E2-Unclassified 177-392 21 1.9e-31 106.36 In-house 150-352 (352) Show / Hide 
Range on Protein: 177-392
Range on HMM: 150-352/352
Sequence Identity: 21% (54 aa)

AQILSAMKKLEKME-IVHLDLKPENICFTSTCTFTTEIRKDVCYISPSEELNVCIIDFGNARKSNQE---------------DLKSSEVVQTQNYR----
||||.. ..| .   |.| |.||||| |.. .                  ....|||||...|..|                . ... ...| ||     
AQILQGLEYLHHKNNIIHRDIKPENILFDNNGK----------------NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYT

APEIFMGLPFSTR----SDVWSFGCILSELYTGELLFYGNDEHD-----TEQLQF-----ELMQLILQQAPSYLMMRK----AAENKKKMICIDGNVYMK
|||...|   ...    .|.||.|.|| |. .|.. ||.|.. .     |... .     .| | |.|. ...  . .       ...   .|       
APEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-NNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFIN------

KRAKSSFDPPLPLYKQRRRNDRAAIPLFELLERILIFDPTRRLTFSEISSETFF
                            .|| ..|  .|  |.||..|    .|
----------------------------DLLQKMLKKNPNKRITFEQILNHPWF
Kinase Y111B2A.1.AA Ciliate-E2 162-392 18 2.2e-28 94.53 In-house 133-365 (365) Show / Hide 
Range on Protein: 162-392
Range on HMM: 133-365/365
Sequence Identity: 18% (55 aa)

NKEIS----FPIATIREIGAQILS---------------AMKKLEKME-IVHLDLKPENICFTSTCTFTTEIRKDVCYISPSEELNVCIIDFGNARKSNQ
|.||.    | .  |..| .|||.               |.. | .   |.| |.||||| |                        ..|||||...| ..
NHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------------------------IKIIDFGLSKKYDD

EDLKSSE-------------------------------VVQTQNYRAPEIFMGLP---------FSTRSDVWSFGCILSELYTGELLFYGNDEHDTEQLQ
.  . ..                               .. | .| ||||..| .          .. .|.||.|.|| |. .|.. |            
DNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF------------

FELMQLILQQAPSYLMMRKAAENKKKMICIDGNVYMKKRAKSSFDPPLPLYKQRRRNDRAAIPLF--ELLER----ILIFDPTRRLT-FSEISSETFF
   .| |.|.  ..    .  . .. .| .  ..  |                    .   ...    |. .    .|  ||  |.| ...|    .|
---QQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKW--K--------------------SWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase Y111B2A.1.AA CAMK 55-310 18 1.4e-24 75.53 In-house 1-361 (425) Show / Hide 
Range on Protein: 55-310
Range on HMM: 1-361/425
Sequence Identity: 18% (70 aa)

VLGEGVFGTVFEVADAEKK------------KKFALKLFK------------------AGHTQFGCEDWVRESELS-IPNYLQIMKSVAA----AHHPNL
.||.| ||.|... . . .            .|.| |  .                     .. . ..|.|.. .  ... ..|||.. .     .|||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLVK---------------SGKMASVPEGYLR----IAILM---ELRGK-----SLFSVMDSTKS--------EVPNKEISFPIATIREIGAQILSAMK
|||                 . ..      .      . . |   |.         ||.   . ..        ..  ..  |. .  | .  ||.||..
IKLYEVYEDPHYFKNTNDYET-SKQ----VF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVH

KLEKMEIVHLDLKPENICFTSTC----------TFTTEIRKDVCYISPSEELNVCIIDFGNARKSNQ-----------------------EDLKSSEVVQ
 . .. |||.||||||| ...             |             ..  |. ||||| |.| ..                       |. | .... 
YCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIF-D-----------WNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCG

TQNYRA-PEIFMG--------------LPFSTRSDVWSFGCILSELYTGELLFYGNDEHDTEQ------LQFELMQLILQ
|  | | ||.. |               . .  .|.|| |.||  . .|.. ||| .. ....       . ||.. |..
TPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMK
Kinase Y111B2A.1.AA TKL 178-296 20 1.5e-20 70.69 In-house 140-296 (364) Show / Hide 
Range on Protein: 178-296
Range on HMM: 140-296/364
Sequence Identity: 20% (33 aa)

QILSAMKKLEKME--------IVHLDLKPENICFTS-TCTFTTEIRKDVCYISPSEELNVCIIDFGNARKSNQEDL-------------------KSSEV
.| ..|  |  |.        |.| |||..||   .   . . ..      ..| .. ...| ||| .|  .|.                     ... .
DIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVS-NYM-----YNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQ

VQTQNYRAPEIFMGL----------------PFSTRSDVWSFGCILSELYTGELLFYGNDEHD
. | .. |||...|                 ..|...||.||| .| |..|... .|.... .
CGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMP
Kinase Y111B2A.1.AA DYRK2 250-306 47 1.4e-19 60.07 In-house 163-215 (318) Show / Hide 
Range on Protein: 250-306
Range on HMM: 163-215/318
Sequence Identity: 47% (27 aa)

VQTQNYRAPEIFMGLPFSTRSDVWSFGCILSELYTGELLFYGNDEHDTEQLQFELMQ
.|.  |||||.. |.....  | ||||||. |||||  || | .| |    || .|.
IQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYPLFPGENEND----QFACMM
Kinase Y111B2A.1.AA DYRK 230-296 43 4.4e-18 64.39 In-house 148-211 (320) Show / Hide 
Range on Protein: 230-296
Range on HMM: 148-211/320
Sequence Identity: 43% (29 aa)

IIDFGNARKSNQEDLKSSEVVQTQNYRAPEIFMGLPFSTRSDVWSFGCILSELYTGELLFYGNDEHD
.|||| .   .|   . .  .|   |||||.. |.|...  |.||.|||| ||.||. || |..| |
VIDFGSSCFEHQ---RIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTGWPLFPGENEYD
Kinase Y111B2A.1.AA p38 190-293 36 7e-17 53.97 In-house 126-208 (289) Show / Hide 
Range on Protein: 190-293
Range on HMM: 126-208/289
Sequence Identity: 36% (38 aa)

EIVHLDLKPENICFTSTCTFTTEIRKDVCYISPSEELNVCIIDFGNARKSNQEDLKSSEVVQTQNYRAPEI-FMGLPFSTRSDVWSFGCILSELYTGELL
.|.| |||| ||  .  |                      | ||| ||   . | .  . |.|  |||||| .    .    |.|| |||. || ||. |
GIIHRDLKPSNIAVNEDCEL-------------------RILDFGLAR---HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMAELITGRTL

FYGND
| |.|
FPGDD
Kinase Y111B2A.1.AA HIPK 228-296 43 9.5e-15 42.4 In-house 144-210 (329) Show / Hide 
Range on Protein: 228-296
Range on HMM: 144-210/329
Sequence Identity: 43% (30 aa)

VCIIDFGNARKSNQEDLKSSEVVQTQNYRAPEIFMGLPFSTRSDVWSFGCILSELYTGELLFYGNDEHD
| .|||| |    .     .  .|   |||||| .||||    |.|| ||.. ||. | .|. |.|| |
VKVIDFGSASHVSKV--VCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFLGWPLYPGADEYD
Kinase Y111B2A.1.AA TyrKc 50-391 18 8.1e-12 -31.61 SMART 1-280 (280) Show / Hide 
Range on Protein: 50-391
Range on HMM: 1-280/280
Sequence Identity: 18% (67 aa)

LENVSVLGEGVFGTVFEVADAEKKKKFALKLFKAGHTQFGCEDWVRESELSIPNYLQIMKSV-AAAHHPNLIKLVKSGKMASVP------EGYLRIAILM
..   .|||| ||.|.. . .    . | |  |...     ||  ||        ..||...    ||||...|.  |   .        | .. .  .|
ITLGKKLGEGAFGEVYK-GTWK--IQVAVKMLKEDA----REDFMRE--------ARIMCKLGG--HHPNIVRLY--GVCTQQGRNFMYIEPLMIVMEYM

ELRGKSLFSVMDSTKSEVPNKEISFPIATIREIGAQILSAMKKLEKMEIVHLDLKPENICFTSTCTFTTEIRKDVCYISPSEELNVCIIDFGNARKSNQE
..   .| .   ... .       .. ..  ..  || . |  |... ..| ||   |.  ..                      | | ||| .|.   .
PHG--DLKDYLRKHRPK-------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-------------------TVKISDFGLSRDIYDD

DLK---SSEVVQTQ--NYR--------APEIFMGLPFSTRSDVWSFGCILSELYTGELLFYGNDE---HDTEQLQFELMQLILQQAPSY----LMMRKAA
| .   ..  ....  . .        ||| ..   |.| |||||||  . |..|     | ...    . ...   ..|      | .           
DQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------

ENKKKMICIDGNVYMKKRAKSSFDPPLPLYKQRRRNDRAAIPLFELLERILIFDPTRRLTFSEISSETF
                                     ..   .... ..   .||  | |||||  | |
-----------------------------------FVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase Y111B2A.1.AA HIPK 162-201 47 1.1e-09 26.12 In-house 93-132 (329) Show / Hide 
Range on Protein: 162-201
Range on HMM: 93-132/329
Sequence Identity: 47% (19 aa)

NKEISFPIATIREIGAQILSAMKKLEKMEIVHLDLKPENI
||    |.  || |  |.| |..|| .. ..| |||||||
NKFMPLPLKHIRPILQQVLTALMKLKELGLIHADLKPENI
Kinase Y111B2A.1.AA DYRK 162-201 42 1.8e-08 28.06 In-house 94-135 (320) Show / Hide 
Range on Protein: 162-201
Range on HMM: 94-135/320
Sequence Identity: 42% (18 aa)

NKEISF-PIATIREIGAQILSAMKKLEKM-EIVHLDLKPENI
|..  | ..  .| .. ||| ..|.|.|  .|.| |||||||
NHFQGFFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENI
Kinase Y111B2A.1.AA DYRK2 167-201 42 9.2e-08 20.96 In-house 99-133 (318) Show / Hide 
Range on Protein: 167-201
Range on HMM: 99-133/318
Sequence Identity: 42% (15 aa)

FPIATIREIGAQILSAMKKLEKMEIVHLDLKPENI
|  . .|  ...|| ... | |  |.| |||||||
FSLQLVRRFAHSILQCLRFLHKNNIIHCDLKPENI
Kinase Y111B2A.1.AA Pkinase_Tyr 257-286 51 6.4e-05 17.29 Pfam 182-212 (270) Show / Hide 
Range on Protein: 257-286
Range on HMM: 182-212/270
Sequence Identity: 51% (16 aa)

APEIFMGLPFSTRSDVWSFGCILSELYT-GE
||| ..   |.| |||||||  . |..| ||
APECINYGKFTTKSDVWSFGVLMWEIFTYGE
Kinase Y111B2A.1.AA RIO1 63-88 29 0.000109 15.09 Pfam 1-27 (200) Show / Hide 
Range on Protein: 63-88
Range on HMM: 1-27/200
Sequence Identity: 29% (8 aa)

TVFEVADAEKKK-KFALKLFKAGHTQF
 |......|. | ..|.|... |.|.|
NVYHAYSMEDGKDECAVKIYRTGTTCF
Kinase Y111B2A.1.AA DYRK2 51-80 36 0.000145 10.4 In-house 2-31 (318) Show / Hide 
Range on Protein: 51-80
Range on HMM: 2-31/318
Sequence Identity: 36% (11 aa)

ENVSVLGEGVFGTVFEVADAEKKKKFALKL
| ..|.| | || |... |   |.. |.|.
EILEVIGKGSFGQVVKCYDHKTKQHVAIKM
Kinase Y111B2A.1.AA p38 50-79 27 0.000276 10.23 In-house 1-33 (289) Show / Hide 
Range on Protein: 50-79
Range on HMM: 1-33/289
Sequence Identity: 27% (9 aa)

LENVSVLGEGVFGTVFEVADAEKKKK---FALK
 .|.. .|.| .|.|  . |.. ..|   .| |
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIK
Kinase Y111B2A.1.AA DYRK 51-80 30 0.003937 7.88 In-house 2-31 (320) Show / Hide 
Range on Protein: 51-80
Range on HMM: 2-31/320
Sequence Identity: 30% (9 aa)

ENVSVLGEGVFGTVFEVADAEKKKKFALKL
| ....| |.|| |. . |   ....|.|.
EILEYIGKGSFGQVVKCWDHKTNEMVAIKI
Kinase Y111B2A.1.AA Ciliate-E2 50-82 27 0.0064 5.84 In-house 1-33 (365) Show / Hide 
Range on Protein: 50-82
Range on HMM: 1-33/365
Sequence Identity: 27% (9 aa)

LENVSVLGEGVFGTVFEVADAEKKKKFALKLFK
 . . ..|.| ||.|... . ...|.||.|...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID
Kinase Y111B2A.1.AA CAMK 368-392 24 0.009998 3.81 In-house 401-425 (425) Show / Hide 
Range on Protein: 368-392
Range on HMM: 401-425/425
Sequence Identity: 24% (6 aa)

LLERILIFDPTRRLTFSEISSETFF
|. ..|  ||..|.| ... .  ..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase Y111B2A.1.AA p38 367-392 38 0.017328 3.99 In-house 264-289 (289) Show / Hide 
Range on Protein: 367-392
Range on HMM: 264-289/289
Sequence Identity: 38% (10 aa)

ELLERILIFDPTRRLTFSEISSETFF
.|||..|. || .|.| .|  .  .|
DLLEKMLELDPDKRITAEEAMQHPYF
Kinase Y111B2A.1.AA Pkinase_Tyr 50-66 41 0.019567 8.87 Pfam 1-17 (270) Show / Hide 
Range on Protein: 50-66
Range on HMM: 1-17/270
Sequence Identity: 41% (7 aa)

LENVSVLGEGVFGTVFE
..   .|||| ||.|..
ITFGKKLGEGAFGEVYK
Kinase Y111B2A.1.AA TKL 376-390 40 0.021028 4.48 In-house 350-364 (364) Show / Hide 
Range on Protein: 376-390
Range on HMM: 350-364/364
Sequence Identity: 40% (6 aa)

DPTRRLTFSEISSET
||. |..|.|| .. 
DPEKRPSFQEILKRL
Kinase Y111B2A.1.AA DYRK 368-392 28 0.02465 4.87 In-house 296-320 (320) Show / Hide 
Range on Protein: 368-392
Range on HMM: 296-320/320
Sequence Identity: 28% (7 aa)

LLERILIFDPTRRLTFSEISSETFF
.... |..||..|.| |.     .|
FIKKCLQWDPHKRITPSQALQHPWF
Kinase Y111B2A.1.AA Ciliate-E2-Unclassified 51-79 27 0.055569 2.69 In-house 2-30 (352) Show / Hide 
Range on Protein: 51-79
Range on HMM: 2-30/352
Sequence Identity: 27% (8 aa)

ENVSVLGEGVFGTVFEVADAEKKKKFALK
. . ..|.| ||.|... . ..|...|.|
KIIKQIGQGGFGKVYKCQHKKQKQYYAMK
Kinase Y111B2A.1.AA TKL 56-65 50 0.133489 1.55 In-house 1-10 (364) Show / Hide 
Range on Protein: 56-65
Range on HMM: 1-10/364
Sequence Identity: 50% (5 aa)

LGEGVFGTVF
.|.| ||.|.
IGSGGFGEVY