Y42A5A.4

Species: Nematode worm
Alias: aSWK171, CE20258, Y42A5A.4
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: V:2.97, WormBase Physical Map location: V: 11108095-11109872

Classification

Group: CMGC
Family: CDKL

Sequence

Name Sequence Type Origin Length Description Download
Y42A5A.4.AA Protein Genbank 353 None Fasta, JSON
Y42A5A.4.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 283 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of Y42A5A.4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Y42A5A.4.AA CDKL 4-286 64 1.5e-215 722.33 In-house 1-286 (286) Show / Hide
Range on Protein: 4-286
Range on HMM: 1-286/286
Sequence Identity: 64% (184 aa)

YDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLKHQNLVGLIEVFKRNRKLHLVFELCDRTVLHELEKNPHGVNDELI
|..|.|.||||||||.||.|..||||||||||.|.||||..||||.|||.|||||||.|.|.|||||.|.|||||||| ||.|||||||..|.||.....
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLKHENIVNLIEVFRRKRKLHLVFEYCDHTVLHELEEYPNGVDEHVV

KKIIYQLLEALKFCHSHKCIHRDVKPENIFLT-RNDQVKLGDFGFARIIN-TTEMYTDYVATRWYRSPELLVGDVQYGPPVDIWAVGCVYAELLTGEALW
.|...|.|.|..|||.|.|||||.|||||..| .|.||||.||||||... ..|.|||||||||||.|||||||.|||.||||||.|||.||...|..||
RKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFARMLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQPLW

PGRSDIDQLYHIRKTLGEFLPRHISIFRTNQFFFGLSIPEPEHLEPLPSKLPNAS-SAQLDFLQKCFEMSPDRRFSCSELMLHGIF
||.|||||||||.|.||...|||..||..|.||.|...||.||.|||....||.| ...|||..||..|.||.|..|..|| | .|
PGQSDIDQLYHIQKCLGPLIPRHQEIFSKNPFFHGMKFPEIEHMEPLEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF

Kinase Y42A5A.4.AA CMGC 4-286 23 2.2e-124 410.93 In-house 1-513 (513) Show / Hide
Range on Protein: 4-286
Range on HMM: 1-513/513
Sequence Identity: 23% (119 aa)

YDRLSKLGEGSYGVVYKCKN--------------RDTGQIVAIKKFVETEDDPHIKK----------IALREIRMLKQLK-----------------HQN
|. ..|.|||.|||||||..              ..|..||||||. . . ... .|          .|||||..||.|.                 | |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

LVGLIEVFKRNR-----------------KLHLVFELCDRTVLHELEKNP--------HGVNDEL------------IKKII------YQLLEALK--FC
.|.|...|...                  .|.||||..| . .. ...|.        .. ..              ||...      ||.|..||  .|
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSHK--CIHRDVKPENIFLTRN--------------------DQVKLGDFGFARIINT----------------------TEMYTDYVATRWYRSPELLV
|||.   |||| ||||| .. |                    ...|..|||.||....                      ...||.||.|||||.||.|.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GD---------VQYGPPVDIWAVGCVYAELLTG--------EALWPGRSD-----------IDQLYHIRKTLGEFL---------------PR-------
|.          .|..|.|.|.|||. ||..||        . |.||.|.           ||||..| |.|| .                ..       
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

------------------HISIFRTNQFFFGLSIPEPE--HLEPLPSKLPN--------------------------------ASSAQLDFLQKCFEMSP
                  |.|.|  |... ... |..   ....|  ..||                                ...  .|.|.|.... |
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

DRRFSCSELMLHGIF
|.| .... . |  |
DKRITAEQALQHPYF

Kinase Y42A5A.4.AA Pkinase 4-286 29 8.5e-99 339.33 Pfam 1-293 (293) Show / Hide
Range on Protein: 4-286
Range on HMM: 1-293/293
Sequence Identity: 29% (89 aa)

YDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALR--EIRMLKQLKHQNLVGLIEVFKRNRKLHLVFELCDRT----VLHELEK--NP
| ...|.|.||.|.||||....||.|||.|..   ....  .....|  ||...| |.| | | |...| .......|.|.|. .     |... .  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

HGV--NDELIKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQV----KLGDFGFARI--INTTEMYTDYVATRWYRSPELLVGDVQYGPPVDIWAV
 ..   .. .|...||.|..|..|||...||||.|||||.. .|...    |..|||.|.   .   . .|... |.||..||.. |.  |||.||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCVYAELLTGEALWPGR----SDIDQLYHIRKTLGEFLPRHISIFRTNQFFFGLSIPEPEHLEPLPSKLPNASSAQLDFLQKCFEMSPDRRFSCSELMLH
||. .|.|.|. ..||.    . .||.. |....|  |.....  ...  || ... . .  . .  . .|.|.. .||. .|... | .| .. ... |
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQH

GIF
  |
PWF

Kinase Y42A5A.4.AA S_TKc 4-286 28 1.6e-97 331.2 SMART 1-231 (231) Show / Hide
Range on Protein: 4-286
Range on HMM: 1-231/231
Sequence Identity: 28% (85 aa)

YDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLKHQNLVGLIEVFKRNRKLHLVFELCDR---TVLHELEKNPHG---
|. | |.|.|..|.||||....||.|||||.           . ..|||..||. .| |.| |..||    .|..|.|.||    .... ..|....   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--VNDELIKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQVKLGDFGFARIINTTEMYTDYVATRWYRSPELLVGDVQYGP-PVDIWAVGCVYAEL
   .   .....||...||..||||. ||||.|||||.|..  ..|..|||.||..      | .. |.||..||.|    .||. ..|.|..||. .|.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEM

LTGEALWPGRSDIDQLYHIRKTLGEFLPRHISIFRTNQFFFGLSIPEPEHLEPLPSKLPNASSAQLDFLQKCFEMSPDRRFSCSELML-------HGIF
|.|. ..|   ........ .                                        |.  .||..||... |..| .. |..        |  |
LCGYPPFP---QMQMMFKKIG----------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase Y42A5A.4.AA CDK 4-218 37 8.7e-97 310.2 In-house 1-242 (284) Show / Hide
Range on Protein: 4-218
Range on HMM: 1-242/284
Sequence Identity: 37% (95 aa)

YDRLSKLGEGSYGVVYKCKNRDTG-----QIVAIKKF-VETE----DDPHIKKIALREIRMLKQLKHQNLVGLIEVFKRN-----------RKLHLVFEL
|..| |.|||.||||||.....||     ||||.||. .|.|    ..  .   |.||| .||.| |.| | |..|.  .           .|| .||| 
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

CDRTVLHELEKNPHGVNDELIKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQ-----VKLGDFGFARIIN-------TTEMYTDYVATRWYRSPE
.|    . ..          || ...|||..| .|||.. .||| || || ...| .     .|..|||.||. .        .  ||  | |.|||.||
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

LLVGDVQYG--PPVDIWAVGCVYAELLT---GEALWPGRSDIDQLYHIRKTLG
|| |. .|.  .|.|.|.|||. ||..|   ...| ||.|.|||| .| ...|
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICG

Kinase Y42A5A.4.AA CDC2 4-218 41 2e-87 268.67 In-house 1-226 (301) Show / Hide
Range on Protein: 4-218
Range on HMM: 1-226/301
Sequence Identity: 41% (95 aa)

YDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKF-VETEDDP-HIKKIALREIRMLKQLK-HQNLVGLIEVFKRNRKLHLVFELCDRTVLHELE-KNP--HG
| .. |.|||.||||||||...|.||||.||. .|.||.   .   |.|||  || || |.|.| | .|..  .|| .||| .|.     .. ..|    
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

VNDELIKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQVKLGDFGFARIINT-TEMYT--DYVATRWYRSPELLVGDVQYGPPVDIWAVGCVYAEL
.  .|.|...||.|... |||... .||| || ||.. .. ..|..||| || ...    ||    | |.|||.||.| |. .|  |||.|..||. ||.
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---LTGEALWPGRSDIDQLYHIRKTLG
    | ..| .| | ||||. | ..||
FMDVTKKPLFHGDSEIDQLFKIFRILG

Kinase Y42A5A.4.AA RCK 4-218 40 5.1e-81 256.75 In-house 1-231 (298) Show / Hide
Range on Protein: 4-218
Range on HMM: 1-231/298
Sequence Identity: 40% (97 aa)

YDRLSKLGEGSYGVVYKCKNRDTGQIVAIK----KFVETEDDPHIKKIALREIRMLKQLK-HQNLVGLIEVFKRNR--KLHLVFELCDRTVLHELEKN--
|  ...||.|.||.| | .| .||.|||||    ||   |.      . ||||. |. |. | |.. |.||.. |    |..|||..| . | .. |.  
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEE-----CMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMD-MNLYQMMKDFK

--PHGVNDEL--IKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTR---------NDQVKLGDFGFARIINTTEMYTDYVATRWYRSPELLVGDVQYGPP
   . .. .   ||.|.||.| .|...|.|   |||.||||| .|          .| .|..||| .| |     ||||| |||||.||.|  . .|  |
ERRKYLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSP

VDIWAVGCVYAELLTGEALWPGRSDIDQLYHIRKTLG
.|||||||. .|| .  .|.|| | |||.. | | .|
MDIWAVGCIMYELYMLRPLFPGSSEIDQIFKICKVMG

Kinase Y42A5A.4.AA CDK7 4-218 40 5.3e-81 215.37 In-house 1-220 (288) Show / Hide
Range on Protein: 4-218
Range on HMM: 1-220/288
Sequence Identity: 40% (89 aa)

YDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFV----ETEDDPHIKKIALREIRMLKQLKHQNLVGLIEVFKRNRKLHLVFELCDRTVLHELEKNPHGVN
|. ....||| ...|||     |||||||||        | .  |   |.||| .|. ..| | .||| .|     . |||.. |    .  . .     
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

DELIKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQVKLGDFGFARIINT-TEMYTDYVATRWYRSPELLVGDVQYGPPVDIWAVGCVYAELLTGE
   || .  ..|  | .|| .   ||| || |  .  | |.|..||| || .    ..||  | |||||.|||| |  .||. ||.|.|||. |||.   
PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRV

ALWPGRSDIDQLYHIRKTLG
   || ||||||  | .|||
PYLPGDSDIDQLTRIFQTLG

Kinase Y42A5A.4.AA CDK5 4-218 41 1.2e-76 241.57 In-house 1-217 (287) Show / Hide
Range on Protein: 4-218
Range on HMM: 1-217/287
Sequence Identity: 41% (89 aa)

YDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLKHQNLVGLIEVFKRNRKLHLVFELCDRTVLHELEKNPHGVNDELI
|... |.||| ||.||| .|..|. |||.|.    ..|  .   |.||| .|| |||.| | |. |   ..|| |||| ||      ...   ... ..|
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

KKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQVKLGDFGFARIINT-TEMYTDYVATRWYRSPELLVGDVQYGPPVDIWAVGCVYAELL-TGEALW
| ..||||  | |||.|.  ||| || |    .| . ||.||| ||        |.  | | ||| |  | |  .|  ..|.| .||..||.  .|  | 
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF

PGRSDIDQLYHIRKTLG
|| .. |||  | | .|
PGNDVEDQLKRIFKIMG

Kinase Y42A5A.4.AA MAPK 4-218 33 1.4e-69 237.48 In-house 1-252 (328) Show / Hide
Range on Protein: 4-218
Range on HMM: 1-252/328
Sequence Identity: 33% (86 aa)

YDRLSKLGEGSYGVVYKCKNRD------TGQIVAIKKFVETEDDPHIKKIALREIRMLKQL-KHQNLVGLIEVFKRN-----------RKLHLVFELCDR
|. |...|.|.|||| ... .       .|..|||||..   ..|.  | ..|||..|. . .| | ..|...|.             . . .|.||.. 
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

TVLHELEKNPHGVNDELIKKIIYQLLEA--LKFCHSHKCIHRDVKPENIFLTRNDQVKLGDFGFARIINTTE---------------MYTDYVATRWYRS
  || . | .   .|. |. ..||.| .  ||. ||   |||| ||.|| .. |...|..||| ||.| ...               . |.||||||||.
D-LHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRA

PELLVGD--VQYGPPVDIWAVGCVYAELLT-GEALWPGRSDIDQLYHIRKTLG
||.. .     |   ||.|.|||  ||.|| .  | ||.. |||. .| ..||
PEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLG

Kinase Y42A5A.4.AA ERK7 4-286 33 8.3e-67 227.45 In-house 1-292 (292) Show / Hide
Range on Protein: 4-286
Range on HMM: 1-292/292
Sequence Identity: 33% (97 aa)

YDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLK-HQNLVGLIEVFK--RNRKLHLVFELCDRTVLHELEKNPHGVND
|. ...|| | ||.| |   . |.|.||.||      ..       ||| .|.... | |.. ||.|..   .| . ||||  . | ||   .  .   |
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFME-TDLHAVIRKGNILKD

ELIKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQVKLGDFGFARIINTTE-------MYTDYVATRWYRSPELLVGDVQYGPPVDIWAVGCVYAE
   . |.|||| |.|. || . ||||.|| || |  .  ||. ||| || |  .|       | |.||||||||.|| |.|  .| . || | .||. .|
IHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGE

LLTGEALWPGRSDIDQLYHIRKTLGEFLPRHISIFRTNQFFFGLSIPEPEHLEPLPSKLPNASSAQLDFLQKCFEMSPDRRFSCSELMLHGIF
.|.| .. || | ..|.  | .|...     |     .     |.  . .. ..|   .|... . .| |..   . |..| .  . . |   
MLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV

Kinase Y42A5A.4.AA p38 4-218 39 3.5e-60 204.32 In-house 1-221 (289) Show / Hide
Range on Protein: 4-218
Range on HMM: 1-221/289
Sequence Identity: 39% (89 aa)

YDRLSKLGEGSYGVVYKCKNRDTGQI---VAIKKFVETEDDPHIKKIALREIRMLKQLKHQNLVGLIEVFKR-NRKLH------LVFELCDRTVLHELEK
| .|. .|.|.|| | |   |.|||    |||||. .   ...  | . ||.| || ..| | ..|..||   .. .       .| .. ..  |. . |
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGAD-LNNIMK

NPHGVNDELIKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQVKLGDFGFARIINTTEMYTDYVATRWYRSPELLVGDVQYGPPVDIWAVGCVYAE
  .  .|. |. ..||.| .||. ||   |||| || || .. .  ..  ||| ||    .|| |.||||||||.|| .   ..|   |||| |||. ||
CQR-LSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR-HCDDEM-TGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMAE

LLTGEALWPGRSDIDQLYHIRKTLG
|.||..| ||   ||||  | | .|
LITGRTLFPGDDHIDQLQRIMKVCG

Kinase Y42A5A.4.AA TyrKc 4-286 21 1e-16 47.63 SMART 1-280 (280) Show / Hide
Range on Protein: 4-286
Range on HMM: 1-280/280
Sequence Identity: 21% (68 aa)

YDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQL--KHQNLVGLIEVFKRN-------RKLHLVFELCDRTVLHE-LEK
   . ||||| .|.|||.. .   . ||.|.  |      .. . .||.|....|  .|.|.| |. |             | .|.|...   |.. | |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDF-MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NPHGVNDELIKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQVKLGDFGFARIINTT-------EMYT------DY--VATRWYRSPELLVGDVQY
. . .. .   .. .|  .   . ||..|||||    |. ...| .|| .||| .| |          ..|.          .  ||. .|| .  .  .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NYGKF

GPPVDIWAVGCVYAELLT-GEALWPG-----RSDIDQLYHIRKTLGEFLPRH---ISIFRTNQFFFGLSIPEPEHLEPLPSKLPNASSAQLDFLQKCFEM
 .  |.|. | .  |..| |.  .||      |... . ....      | .   .|                       .  . ....  .  ..| . 
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-----------------------F--VCCPDEMYQIMKQCWHE

SPDRRFSCSELMLHGIF
 |. | . ||.  | .|
DPEDRPTFSEI--HECF

Kinase Y42A5A.4.AA Pkinase_Tyr 4-158 28 1.2e-16 57.04 Pfam 1-169 (270) Show / Hide
Range on Protein: 4-158
Range on HMM: 1-169/270
Sequence Identity: 28% (48 aa)

YDRLSKLGEGSYGVVYKCKNR----DTGQIVAIKKFVETEDDPH--IKKIALREIRMLKQL-KHQNLVGLIEVFK-RNRK--LHLVFELCDR-TVLHELE
   . |||||..|.|||.. .    .|.. ||.|.  |. ....  ...  .||....||| .|.|.| |. |   . .   . .|.|..     |. | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDF-MREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KN---PHGVNDELIKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQVKLGDFGFARIINTTEMY-T
|.   .. .. . . .. .|  ... . .|..|||||.   |. .|.| .|| .||| || |  .. | .
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYR

Kinase Y42A5A.4.AA CDK 250-286 29 1e-06 17.01 In-house 253-284 (284) Show / Hide
Range on Protein: 250-286
Range on HMM: 253-284/284
Sequence Identity: 29% (11 aa)

SKLPNASSAQLDFLQKCFEMSPDRRFSCSELMLHGIF
.|||.      |.|.|.. . |..|.|... . |  |
TKLPDY-----DLLNKMLCYDPKKRISAEQALQHPYF

Kinase Y42A5A.4.AA CDK7 255-286 28 0.000286 6.8 In-house 257-288 (288) Show / Hide
Range on Protein: 255-286
Range on HMM: 257-288/288
Sequence Identity: 28% (9 aa)

ASSAQLDFLQKCFEMSPDRRFSCSELMLHGIF
||   ||.... . | | .| .|..   .  |
ASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF

Kinase Y42A5A.4.AA CDK5 241-286 21 0.000716 7.58 In-house 241-287 (287) Show / Hide
Range on Protein: 241-286
Range on HMM: 241-287/287
Sequence Identity: 21% (10 aa)

EPEHLEP-LPSKLPNASSAQLDFLQKCFEMSPDRRFSCSELMLHGIF
.. .... . .  |. ..  .|.|||  .. |. | |  . . |  |
PMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF

Kinase Y42A5A.4.AA p38 252-286 34 0.000882 8.48 In-house 255-289 (289) Show / Hide
Range on Protein: 252-286
Range on HMM: 255-289/289
Sequence Identity: 34% (12 aa)

LPNASSAQLDFLQKCFEMSPDRRFSCSELMLHGIF
...|.   .| | |  |. ||.| . .| | |  |
FMGANPQAIDLLEKMLELDPDKRITAEEAMQHPYF

Kinase Y42A5A.4.AA MAPK 252-286 30 0.043179 2.76 In-house 290-328 (328) Show / Hide
Range on Protein: 252-286
Range on HMM: 290-328/328
Sequence Identity: 30% (12 aa)

LPN----ASSAQLDFLQKCFEMSPDRRFSCSELMLHGIF
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FPNANFNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF

Kinase Y42A5A.4.AA RCK 247-286 25 0.07866 1.26 In-house 259-298 (298) Show / Hide
Range on Protein: 247-286
Range on HMM: 259-298/298
Sequence Identity: 25% (10 aa)

PLPSKLPNASSAQLDFLQKCFEMSPDRRFSCSELMLHGIF
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PLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQALQHPYF