Gene Y43D4A.6 (Nematode worm)

Y43D4A.6

Species: Nematode worm
Alias: Y47D3A.16, CE21879, Y43D4A.6, Y113B8_04829, Y113B8_04829 Y43D4_04839, CE22045, aSWK022, aSWK036, Y47D3A.r
External Links: Wormbase Link
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CHK1

Sequence

Name Sequence Type Origin Length Description Download
Y43D4A.6.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 260 Kinase domain by global Sugen HMM Fasta, JSON
Y43D4A.6.AA Protein Genbank 328 None Fasta, JSON

Protein domain

Protein domains of Y43D4A.6.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Y43D4A.6.AA CHK1 6-265 48 4.5e-180 604.51 In-house 1-276 (276) Show / Hide 
Range on Protein: 6-265
Range on HMM: 1-276/276
Sequence Identity: 48% (133 aa)

FKPIKSIGKGAFGQVFLAEKLNNPRIKVAMKKINIFGAP-KEFLEQ-IQQEYYIQKNMK----HKNIVKMYGMSMDTEFCYLFQEFVTGGDLFEKIDFEN
.......|.||||||.|.|...||...||||.|.|.|.. ..|... |..||.|||...    |.|...|.||.||.||.|||.|...|||||.||....
YEVVQTLGEGAFGQVKLCENQRNPEEAVAMKEIHIKGQHKMCFMDNDIRKEYCIQKMLSKIGKHENVIRMMGMRMDPEFYYLFMEYADGGDLFDKIEPDC

GMPVNQVKGYLKQLMSGLKYIHGCG-IVHRDIKPDNLLINSSD------ALKIADFGLSTRFI-VDDKEILLHERIGTTPFMAPELFAKKKHRGPPVDIW
|||......|.|||.|||||||.|| ..||||||.|||....|      .||||||||.|... .|..|..|..|.||.|.||||....|..||||||||
GMPSDEAHRYFKQLISGLKYIHCCGGVTHRDIKPENLLLDKHDSNDMPDNLKIADFGLATWYRRHDGEERMLDKRCGTPPYMAPEVCTGKQYRGPPVDIW

SAGILVFSLLTGNLPWDEPK-ESDILYSQWMNNK-TSKNCIWYGLSTPVVRFLKKLLKENVNERATIEEIESDPWL
|.|......|||.||||.|. .... |..||.|| ....|.|..........|.|.|.||.|.|||||.||.|||.
SCGVVLMAMLTGELPWDQPSHMDCQEYCWWMDNKHWMHWCPWSKIDCRAICLLRKILCENPNKRATIEQIEKDPWY
Kinase Y43D4A.6.AA CAMKL 6-265 31 3.5e-114 365.81 In-house 1-297 (297) Show / Hide 
Range on Protein: 6-265
Range on HMM: 1-297/297
Sequence Identity: 31% (93 aa)

FKPIKSIGKGAFGQVFLAEKLNNPRIKVAMKKINIFGAP-KEFLEQ------------IQQEYYIQKNMK---HKNIVKMYGMSMDTEF------CYLFQ
.. .| .|||.||.| ||.   ....|||.| |.....  ... ..            |..|. |.| ..   |.||.|.| .  . |.      .||. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFVTGGD--LFEKI--DFENG--MPVNQVKGYLKQLMSGLKYIHGCGIVHRDIKPDNLLINSSD--ALKIADFGLSTRFI-V-DDKEILLHERIGTTPFM
| . ||.  ||..|    . .  || .. . | .|..|...|.| .|||||||||.|.|. ...   .||.|||.|. .. . . .. .|... |. |.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APELFAK--KKHRGPPVDIWSAGILVFSLLTGNLPWDEP-----KESDILYSQWMNNKTSKNC-IWYGLSTPVVRFLKKLLKENVNERATIEEIESDPWL
|||.|..  |...||.|||||.|.. . ...|.||.|..     . ..| |  |..... ..  ||| .| .. ....|.|. | ..|.||..|...||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase Y43D4A.6.AA CAMK 11-265 18 4.8e-92 296.84 In-house 1-425 (425) Show / Hide 
Range on Protein: 11-265
Range on HMM: 1-425/425
Sequence Identity: 18% (77 aa)

SIGKGAFGQVFLAEKLNNPR-----------IKVAMKKINIFGAPK-------------------------EFLEQ-IQQEYYIQKN-------MKHKNI
 .|.|.||.|.|..  |...            |||.| |.   ...                         .. .. ...|. | |.       ..|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKMYGMSMD-------------------TEFCYLFQ---EFVTGG----DLFEKIDFENG---------------MPVNQVKGYLKQLMSGLKYIHGCGI
.|.| .  |                   ....|..    |...||    |||..|    .               ..  ... | .|. |...|.| ..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDIKPDNLLINSSD----------------A-LKIADFGLSTRFIVDDKEI---------------------LLHERIGTTPFMA-PELFAK------
||||.||.|.|.....                . .||.|||....|. ....                      ..... || ..|| ||.. .      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------KKHRGPPVDIWSAGILVFSLLTGNLPWDEPKESDIL---------YSQWMNNKTSKNC-IWYGLST-----------------------PVVR
       |.  ||..|.||.|.. . .|.| .|........|.         |  . . .. |   ... .|.                        .  
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FLKKLLKENVNERATIEEIESDPWL
...|.|. . ..|.|||.. ..||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase Y43D4A.6.AA S_TKc 6-265 27 5.3e-82 279.64 SMART 1-231 (231) Show / Hide 
Range on Protein: 6-265
Range on HMM: 1-231/231
Sequence Identity: 27% (75 aa)

FKPIKSIGKGAFGQVFLAEKLNNPRIKVAMKKINIFGAPKEFLEQIQQEYYIQKNMKHKNIVKMYGMSMDTEFCYLFQEFVTG--GDLFEKIDFENG---
.. .. |||||||.|... . .    .||.|.|.         |.|..|  | |. .|.||||.|..  | .. |.. |.. |  ||||. |.  ..   
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---MPVNQVKGYLKQLMSGLKYIHGCGIVHRDIKPDNLLINSSDALKIADFGLSTRFIVDDKEILLHERIGTTPFMAPELFAKKKHRGPPVDIWSAGILV
   .|  ... |..|. ..|.|.|  ||.|||.||.|.|...   .||.||||....         .  .||  .||||..   .. ....|.|| |...
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

FSLLTGNLPWDEPKESDILYSQWMNNKTSKNCIWYGLSTPVVRFLKKLLKENVNERATIEEIES-------DPWL
. .|.|  |..   . . .. . .             | ..  |..|.|. . ..| |. |.         .||.
YEMLCGYPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Y43D4A.6.AA Pkinase 6-265 26 1.6e-73 255.32 Pfam 1-293 (293) Show / Hide 
Range on Protein: 6-265
Range on HMM: 1-293/293
Sequence Identity: 26% (79 aa)

FKPIKSIGKGAFGQVFLAEKLNNPRIKVAMKKINIFGAPKEFLEQIQQ--EYYIQKNMKHKNIVKMYGMSMDTEFCYLFQEFVTGG----DLFEKID--F
.. .. ||.|.||.|... . .... .||.|.|.  .. ......     | .| |...|.|||..|.. .|   .|. .|.. ||    |||. |    
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

ENGM--PVNQVKGYLKQLMSGLKYIHGCGIVHRDIKPDNLLINSSDAL----KIADFGLSTRFIVDDKEILLHERIGTTPFMAPELFAKKKHRGPPVDIW
....  . ...| |..|. .||.|.| .||.|||.||.|.||.. . .    ||.||||.  |    .   .. . || ..||||.  . .. ||.||.|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SAGILVFSLLTGNLPWDEP-----KESDILYSQWMNNKTSKNCIWY------------------GLSTPVVRFLKKLLKENVNERATIEEIESDPWL
|.|.... .|.|..|...       . . .. . |  ... .. |                    .| .   |.|..|. . ..| |.|.|  .||.
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase Y43D4A.6.AA Ciliate-E2 6-265 23 3.2e-66 226.31 In-house 1-365 (365) Show / Hide 
Range on Protein: 6-265
Range on HMM: 1-365/365
Sequence Identity: 23% (88 aa)

FKPIKSIGKGAFGQVFLAEKLNNPRI-----------------KVAMKKINIFGAPKEFLEQIQQEYYIQK----------------NMKHKNIVKMYGM
.| || ||.|.||.|..... ....                  ||..|....    |  .||| || .| .                ...|.||.|||  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

SM--DTEFCYLFQEFVTGGDLFE------KIDFEN-----GMPVNQVKGYLKQLMS---------------GLKYIHGCG-IVHRDIKPDNLLINSSDAL
    |.. .||  |.. |||||.      |  ...      .  ...| . ||. .               .|.|.|  . |.||||||.|.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIADFGLSTRFIVDDK--------EILLHER----------------------IGTTPFMAPELFAKKK--------HRGPPVDIWSAGILVFSLLTGNL
||.|||||...  | .        ....  .                      .|| ..|||| . .||        . .  .||||.|.. . .|.|..
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PWDEPKESDILYSQWMNNKTSKNCI---------------WYGLSTPVVRFLKK----LLKENVNERAT-IEEIESDPWL
|.         . | ...| . .|                |  .|  .  ..||    .|. . ..| | .|.|   ||.
PF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase Y43D4A.6.AA Ciliate-E2-Unclassified 6-265 22 2.1e-59 203.66 In-house 1-352 (352) Show / Hide 
Range on Protein: 6-265
Range on HMM: 1-352/352
Sequence Identity: 22% (79 aa)

FKPIKSIGKGAFGQVFLAEKLNNPRIKVAMKKIN--------IFGAPKEFLEQIQQEYYIQ---------------KNMKHKNIVKMYGMSMDTEFCYLF
.| || ||.|.||.|..... ..   . ||| ..        .    .|.. .....  ..               .|..| .||||. .  |.. .|. 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

QEFVTGGDLFEKIDFENG-----------------MPVNQVK-----GYLKQLMSGLKYIHGCG-IVHRDIKPDNLLINSSD---ALKIADFGLSTRFIV
 |.. ||||.. |   ..                  . .|.|      |..|. .||.|.|  . |.||||||.|.|....     .||.|||.| . . 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

DDK-------------EILLHERIGTTPFM----APELFAKKKHRGP---PVDIWSAGILVFSLLTGNLPWDEPKESD---------------ILYSQWM
...             . ... ..||  .|    |||.. .... ..    .|||| |.. . .|.|..| . ... .               .||.. .
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

NNKTSKNCIW-----YGLSTPVVRFLK----KLLKENVNERATIEEIESDPWL
........ .     ...|  .  |..    |.|| | |.| |.|.|   ||.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase Y43D4A.6.AA Ciliate-E2a 6-218 32 8.2e-59 171.76 In-house 1-227 (275) Show / Hide 
Range on Protein: 6-218
Range on HMM: 1-227/275
Sequence Identity: 32% (73 aa)

FKPIKSIGKGAFGQVFLAEKLNNPRIKVAMKKINIFGAPKEFLEQIQQEYYIQKNMKHKNIVKMYGMSMDTEFCYLFQEFVTGGDLFEKIDFENGMPVN-
.| || ||||.||.|.||......  ....| |. .   |.  |....|  | ....|.|| |.|.  .|    ||  |.. ||.|..||     .  . 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI

-QVKGYLKQLMS-GLKYIHGCGIVHRDIKPDNLLIN--SSD-----ALKIADFGLSTRFIVDDKEILLHERIGTTPFMAPELFAKKK---HR--GPPVDI
 ... ...|| . || |.|  .|.|||.||.|.|..  |..      .||.||||.|..  |.|.  .. . ||  ..|||... |    |.  .  .|.
QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKY-MFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM

WSAGILVFSLLTGNLPWDEPKESDILYS
||.|.  . ||.| .| .  ....||..
WSCGVIFYILLCGKPPFKGKTYNEILQQ
Kinase Y43D4A.6.AA ULK 6-265 23 2.9e-55 189.93 In-house 1-324 (324) Show / Hide 
Range on Protein: 6-265
Range on HMM: 1-324/324
Sequence Identity: 23% (76 aa)

FKPIKSIGKGAFG-QVFLAEKLNNP--RIKVAMKKINIF-GAPKEFL-------EQIQQEYYIQKNMK---HKN--IVKMYGMSMDT--EFCYLFQEFVT
.  .. .|||.|| .|. ... ..     .|| |.|...    |. .       .....|  |.| .|   |.|  |||.| .....   ..|...|.  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLFEKIDFENGMPVNQ----------VKGYLKQLMSGLKYIHGCGIVHRDIKPDNLLINSSDA------------LKIADFGLSTRFIVDDKE-ILLH
||||.. |   .. |. .          .....||...|.|..|  .|.||||||.|.||.  ..            |||||||..  .  ...|  ...
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

ERI------GTTPFMAPELFA---KKKHRGPP-VDIWSAGILVFSLLTGNLPWDEPKESDIL------------YSQWMNNKTSKNCIW----YGLSTPV
.        ||  .|||...    ..|. .   .|||| |.. . .|.|  |. ..  .|              . | . ...  ..      . .|  .
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQ-QIYIKNQPIQFPKPPKDPKISPEC

VRFLKKLLKENVNERATIEEIESDPWL
  .....|. . ..| ..||| . ||.
KDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase Y43D4A.6.AA ULK 6-265 23 8.1e-55 188.44 In-house 1-329 (329) Show / Hide 
Range on Protein: 6-265
Range on HMM: 1-329/329
Sequence Identity: 23% (76 aa)

FKPIKSIGKGAFGQVFLAEKLNNP---RIKVAMKKINIF-GAPKE-------FLEQIQQEYYIQKNMK----HKN----IVKMYGMSMDTEF--CYLFQE
.  .. .|||.||.|. ... ..     .||| |.| ..    |.       .......|  |.| .|    |||    |||.| ..... .  .|...|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FVTGGDLFEKIDFENGMPVNQ----------VKGYLKQLMSGLKYIHGCGIVHRDIKPDNLLINSSDA------------LKIADFGLSTRFIVD-DKEI
.  ||||.. |   ...| ..          .. ..||...|.|..|  .|.||||||.| ||.  ..            |||||||..  .  | . . 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LLHERI------GTTPFMAPELFA---KKKHRGPP-VDIWSAGILVFSLLTGNLPWDEPKESDILYSQWMNNKT----------SKNCIWYG------LS
...         ||  .|||...    ..|. .   .|||| |.. . .|.|  |. ..  .|    . ....           ...  ..       .|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

TPVVRFLKKLLKENVNERATIEEIESDPWL
  .  .....|. . ..| ..||. . ||.
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase Y43D4A.6.AA STE 6-265 21 1.7e-49 170.74 In-house 1-359 (359) Show / Hide 
Range on Protein: 6-265
Range on HMM: 1-359/359
Sequence Identity: 21% (79 aa)

FKPIKSIGKGAFGQVFLAEKLNNPRIK--------------VAMKKINIFGAPK---------------EFLEQIQQEYYIQKNMK--HKNIVKMYGMSM
.. |. |||||||.|..| . .|..|               .|.|..|.    .               | ..||..|  | |...  |.|||| ||. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DT-------EFCYLFQEFVTGGDLFEKID------FEN--------GMPVNQVKGYLKQLMSG-LKYIHGCGIVHRDIKPDNLLINSSDALKIADFGLST
.        . .... |.. || | . |.      ...         .| .|.. ...|.  | |.|.|  .|.||||||.| |.      |..|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

RFIVDDKEILLHE----------------RIGTTPFMAPELFAK-----KKHRGPPVDIWSAGILVFSLLTGNLPWDEPKESDILYSQWMNN--------
... .  .| . .                 .||  .||||   .     .|. .  .|||| |...  ..||. || . .    ..   .|.        
QLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----KTS---KNCIW---------------YGLSTPVVRFLKKLLKENVNERATIEEIES--DPWL
     ...   .. .                  .| .   |..| |. . |.|.| ..  .   |..
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase Y43D4A.6.AA MARK 111-265 36 2.3e-49 159.6 In-house 111-262 (262) Show / Hide 
Range on Protein: 111-265
Range on HMM: 111-262/262
Sequence Identity: 36% (58 aa)

KQLMSGLKYIHGCGIVHRDIKPDNLLINSSD--ALKIADFGLSTRFIVDDKEILLHERIGTTPFMAPELFAKKKHRGPPVDIWSAGILVFSLLTGNLPWD
.|. |...| |  .||||||||.|.|| .      ||.|||.|.... . |   | .  || |.||||.| ||.  ||.||||| |.. . ...|..|.|
RQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQK---LNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFD

EPKESDILYSQWMNNKTSKNCI-WYGLSTPVVRFLKKLLKENVNERATIEEIESDPWL
   .... | . . . .. ..   . .|.    ....||. | .||.|||||...||.
---GDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase Y43D4A.6.AA Pkinase_Tyr 6-151 26 5.7e-21 71.64 Pfam 1-158 (270) Show / Hide 
Range on Protein: 6-151
Range on HMM: 1-158/270
Sequence Identity: 26% (42 aa)

FKPIKSIGKGAFGQVFLAEKL---NNPRIKVAMKKINIFGAPKE-FLEQIQQEYYIQKNM-KHKNIVKMYGMSM-DTEF--CYLFQEFVTGGDLFEKIDF
 . .| .|.||||.|....      |..|.|| |...    ... ..|   .|  | |.. .|.|||..||  . . |    |.  |.. .||| .    
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----ENGMPVNQVKGYLKQLMSGLKYIHGCGIVHRDIKPDNLLINSSDALKIADFGLS
    ..  .. .  ..  |  .|. | .  ...|||.   | |....   ||.||||.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase Y43D4A.6.AA TyrKc 6-268 22 5.3e-15 19.83 SMART 1-280 (280) Show / Hide 
Range on Protein: 6-268
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

FKPIKSIGKGAFGQVFLAEKLNNPRIKVAMKKINIFGAPKEFLEQIQQEYYIQKNM--KHKNIVKMYGMSMDT-------EFCYLFQEFVTGGDLFEKID
 . .| .| ||||.|....      |.|| |...        .| . .|  | ..   .|.|||..||  ..        |  ..  |.. .||| . . 
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

FENG-MPVNQVKGYLKQLMSGLKYIHGCGIVHRDIKPDNLLINSSDALKIADFGLSTRFIVDD------KEILLHER--IGTTPF----MAPELFAKKKH
   .  .. .   .  |  .|  |.|  ...|||.   | |...    ||.||||| |.| ||      |.   .     | |..    |||| . ... 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLS-RDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGK

RGPPVDIWSAGILVFSLLT-GNLPWDEP----KESDILYSQWMNN---KTSKN--------CIWYGLSTPVVRFLKKLLKENVNERATIEEIESDPWLED
  .  |.|| |.. . ..| |  |. ..    .. . .. . ..    .  .|        |     .. . .  |.  .|. ..| | .||      |.
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCC-----PDEMYQIMKQCWHEDPEDRPTFSEI-----HEC

L
.
F
Kinase Y43D4A.6.AA MARK 6-70 30 1.2e-08 24.52 In-house 1-65 (262) Show / Hide 
Range on Protein: 6-70
Range on HMM: 1-65/262
Sequence Identity: 30% (20 aa)

FKPIKSIGKGAFGQVFLAEKLNNPRIKVAMKKINIFGAPK-EFLEQIQQEYYIQKNMKHKNIVKMY
.| .| ||.|....| ||  ..   .||| | .. |   . . .. .. |  | | ..|.||.|..
YKMLKTIGHGSYAKVKLACHKHTG-RKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLF