Gene Y47G6A.13 (Nematode worm)
Y47G6A.13
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| Y47G6A.13.AA | Protein | Genbank | 468 | None | Fasta, JSON |
| Y47G6A.13.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 265 | Kinase domain by global Sugen HMM | Fasta, JSON |
Protein domains of Y47G6A.13.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | Y47G6A.13.AA | TTBKL | 25-289 | 42 | 2.9e-145 | 488.89 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 25-289 Range on HMM: 1-288/288 Sequence Identity: 42% (121 aa) WRIKALLGKGACGVVYKVEDKNRKGYCAAMKVEYDS-EEFDRTLQLEVNVLSKLT--DSRDVLKLIDYGKRKLYRYMVTTLCGKDLMALRMKIQRG--FN |.|. ..|.|..|.||.|.|...|..|||||.|... | |.....||.||.|| .|. ..|....|||| |..|| ||||..|..||...... |. WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS DATAMRVAVFTLYGLKQLHEAGYVHRDVKPGNIMTAANK--GRDARVMLLIDFGMARTFVMAGDDG-------KKKLRPMRR---RIPLRGTIRYCSMNV | |..|... .||.|||.|..|..||||||.|... ... ....|...|||||||| ... ... |...|..|. . |.|||.||||.|. DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM HERKEQGRCDDLVAMIYSIVYLTLGLPWSNLKDEKEIMSMKKSTKDLALFED------LPDELKSIFEYLRTLSYADRPNYEKIYNLL |.||||||.|||....|.|..| .||||.|..|..||..|||..|| .|| | .|.|. .....||.|.|.|||.||.||... HDRKEQGRHDDLWSWMYMIIELHCGLPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF |
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| Kinase | Y47G6A.13.AA | CK1 | 25-285 | 28 | 1.7e-103 | 350.13 | In-house | 1-339 (339) | Show / Hide |
Range on Protein: 25-285 Range on HMM: 1-339/339 Sequence Identity: 28% (98 aa) WRIKALLGKGACG-VVYKV-----EDKNRKG----YCAAMKVEY-DSEEFDRTLQLEVNVLSKLTD----------SRDVLK----------LIDYGKRK |... ..|.|..| .||| .|..... ..||||| .|. ...|. |.... ||.. .. ..| ....|... WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED LYR-YMVTTLCGKDLMALRM---KIQRGFNDATAMRVAVFTLYGLKQLHEAGYVHRDVKPGNIMTAANK-----------GRDARVMLLIDFGMAR-TFV | ||| ||.|..|. ||. .| |.. |....|. .|..|...|..|..|||.||.|.. .|. ....|.. .||||||| .. DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR MAGDDG--------KKKLRPMRR---RIPLRG-TIRYCSMNVHERKEQGRCDDLVAMIYSIVYLTLG---LPWSNLKDEKE-----IMSMKKSTKDLALF . .... ....|| |. . ..|| |.||||.|.|..||||| |||....| ..... | |||.|.|||.. .. ||. .| .. DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM ED------------LPDELKSIFEYLRTLSYADRPNYEKI . .|.|. |..|.|.|.| |||.||.| STPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI |
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| Kinase | Y47G6A.13.AA | Worm6 | 25-285 | 32 | 2.3e-65 | 223.48 | In-house | 1-279 (279) | Show / Hide |
Range on Protein: 25-285 Range on HMM: 1-279/279 Sequence Identity: 32% (92 aa) WRIKALLGKGACGVVYKVEDKNRKG-YCAAMKVEYDSEEFDRT-LQLEVNVLSKLTDSR--DVLKLIDYGKRKL--YRYMVTTLCGKDLMALRMKI-QRG | . ...|.|..| ||||||| .| |||.| |.. | |..|..|| ... .. ..|..|.|| . ..|.| ||.||.|. ||. .| WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK FNDATAMRVAVFTLYGLKQLHEAGYVHRDVKPGNIMTAA---NKGRDARVMLLIDFGMARTFVMAGDDGKKKLRPMR-RRIPLRGTIRYCSMNVHERKEQ | .|....| ..| .. .|| .|..|||||||| .. . ..||||.| ... ..... ||. | ... ||| ||.. . | ..|| FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNE--LRTPRWTACGFRGTVRYAPLACHKGQEQ GRCDDLVAMIYSIVYLTLG-LPWSNLKDEKEIMSMKKS---TKD----LALFEDLPD-ELKSIFEYLRTLSYADRPNYEKI .| ||. | .| ...| ||| ..||... || ... .|. | |.. |..|. ..|| |||.|..| CRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI |
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| Kinase | Y47G6A.13.AA | TTBK | 25-285 | 34 | 2.9e-50 | 173.31 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 25-285 Range on HMM: 1-257/257 Sequence Identity: 34% (90 aa) WRIKALLGKGACGVVYKVEDKNRKGYCAAMKVEYDSEEFDRTLQLEVNVLSKLTDSRDVLKLIDYGKRKLYRYMVTTLCGKDLMALRMKIQRG-FNDATA |.... | |. | .| .| . . |.||| .. |..|| || || | . | | . ||| .| || | || | || |. |. WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVE-SAQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTT MRVAVFTLYGLKQLHEAGYVHRDVKPGNIMTAANKGRDARVMLLIDFGMARTFVMAGDDGKKKLRPMRRRIPLRGTIRYCSMNVHERKEQGRCDDLVAMI .|. | | .... |. |. |||.|| | | | ..|||.|| .. | . || | |||.|| | | | .| || ||| . LRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRN-PSTCRKCYMLDFGLARQYTNACGE----VRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLF YSIVYLTLG-LPWSNLKDEKEIMSMKKSTKDLALFEDLPDELKSIFEYLRTLSYADRPNYEKI | | | ||| .|| .. .||. | ...| |.. . .. | |.|||.| | YMLVEFVQGQLPWRKIKDKDQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI |
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| Kinase | Y47G6A.13.AA | CK1 | 25-283 | 27 | 1.8e-28 | 95.27 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 25-283 Range on HMM: 1-271/271 Sequence Identity: 27% (76 aa) WRIKALLGKGACGVVYKVEDKNRKGYC--AAMKVEYDSEEFDRTLQLEVNVLSKLTD------SRDVLKLIDYGKR--KLYRYMVTTLCGKDLMALRMKI |. .| |. |..|.... .| |.|.| . |. |. .. | . . . ... .|. . | .||..| |..| | .. YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSK-HPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFC QRGFNDATAMRVAVFTLYGLKQLHEAGYVHRDVKPGNIMTAANKGRDARVMLLIDFGMARTFVMAGDDGKKKLRPMRRRIPLRGTIRYCSMNVHERKEQG .| | | . .| . . .|. ...|||.|| |.. .|... . .||||.| .. || .. | | .| || || | | | .||. NRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGR-YGKHCHQVYIIDFGLAKRYR---DDKTHQHIPYRENKNLTGTARYASINTHLGIEQS RCDDLVAMIYSIVYLTLG-LPWSNLK-DEKE-----IMSMKKSTKDLALFED-LPDELKSIFEYLRTLSYADRPNYE | ||. .. | ..|. | ||| .|| ..|. || .| || |... .| |. ..| | |.....|.|. RRDDMESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM |
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| Kinase | Y47G6A.13.AA | CK1-Unique | 25-287 | 17 | 7.9e-28 | 93.56 | In-house | 1-337 (337) | Show / Hide |
Range on Protein: 25-287 Range on HMM: 1-337/337 Sequence Identity: 17% (59 aa) WRIKALLGKGACGVVYKVEDKNRK-------GYCAAMKVEYDSEEFD----RTLQLEVNVLSKLT----DSRDVLKLIDYGKRKLYRYMVTTLCGKDLMA | . ...|.| | |..| . |. || || |. . .... ..|.. ..| .....| . . . ..| |. |. . WCVIKHIGYGGYGCVHRVIFVNNGTFRIDDDMYC--MKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDFHQHRDWWWIVMTMHGPSMEE LRMKIQR-GFNDA------TAMRVAVFTLYGLKQLHEAGYVHRDVKPGNIMTAANKGRDARVMLLIDFGMART--FVMAGDDGKKKLRPMRRRIPLRGTI ..|. . | .| . . .| .. |..|. ||. ||.|. . |... . .. .|.| | || . .|. | ..| ||. CCMMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFV----SNNHQIRQPRPITPFRGCK RYCSMNVHERKEQGRCDDLVAMIYSIVYLTLG---------------------------------------------------------LPWSNLKDEKE .||. |. .|.|| ||. |... | .. ..|. |.... DYCPCSCHQCREHGRRDDMESWFYMLYHLVHNTRGLSWKLDKIIPSGIDNIIVYLRGLKFEDPVDYRQIENELRTAGKKMAPSDSSDEKMCWKGLRRQNA IMSMKKSTKDLALFEDLPDELKSIFEYLRTLSYADRPNYEKIYN . |. . . | ..| . .| ... . | . |. . | YDKHKNYQN-SKQFNEKPCLFCKIKPHNDMKMYCCMSEYFYMFN |
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| Kinase | Y47G6A.13.AA | Dual | 25-289 | 26 | 8.6e-24 | 76.78 | In-house | 1-282 (282) | Show / Hide |
Range on Protein: 25-289 Range on HMM: 1-282/282 Sequence Identity: 26% (76 aa) WRIKALLGKGACGVVYKVEDKNR---KGYCAAMKVEYDSEE-FDRTLQLEVNVLSKLTD---------SRDVLKLIDYGKRKLYR--YMVTTLCGKDLMA |.. ||| | ..||.| . .. | | ..|.| . .| | |. | | . . . ..|||| . . |.| . | | WKVVNLLGSGGFRDVYHVHRFSQVNPKNKCYILKTESEEGEKMMLRLKVEMQVMMKFAEKRKKEKIPGDKCFIEFVDYGKCEQDKCKYWVMSPYGPSLQE LRMK-IQRGFNDATAMRVAVFTLYGLKQLHEAGYVHRDVKPGNIMTAANKGRDARVMLLIDFGMARTFVMAGDD-GKKKLRPMRRRIPLRGTIRYCSMNV | | | .. .. || .| .. || .||.||..|| | . . | .. ||...|... | || |. | . |. || . IRRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGLGM-DETTVYMQ-DFRIVRKYI----DPENKKHRTARKKVKMYGCGRYACRAC HERKEQGRCDDLVAMIYSIVYL---TLGLPWSNLKDEKEIMSMK---KSTKDLALFEDLPDELKSIFEYLRTLSYADRPNYEKIYNLL |.||| ||| . || . .| |..| .. | .... | . ..| . | .|| . | ..| | |. . | | MMQKDQGRKDDLECWIYMVFDLMDPEHGMSWRKECDCNMMIKQKDNFMYHFDKHQYSHIPRRLKPLVSYVNGYQYDSTPDYDYFRNCL |
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| Kinase | Y47G6A.13.AA | CK1-D | 95-285 | 31 | 7.8e-23 | 77.27 | In-house | 69-261 (261) | Show / Hide |
Range on Protein: 95-285 Range on HMM: 69-261/261 Sequence Identity: 31% (63 aa) YRYMVTTLCGKDLMALRMKIQRGFNDATAMRVAVFTLYGLKQLHEAGYVHRDVKPGNIMTAANKGRDARVMLLIDFGMARTFVMAGDDGKKKLRPMRRRI | || | | | | .| | | . .| . .. .| ..|||.|| | . |. .. .||||.|. . | .. | | YNVMVMDLLGPSLEDLFNYCHRKFSLKTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGL--GKRGNMVYIIDFGLAKRYR---DARTHQHIPYRENK PLRGTIRYCSMNVHERKEQGRCDDLVAMIYSIVYLTLG-LPWSNLKDE------KEIMSMKKSTKDLALFEDLPDELKSIFEYLRTLSYADRPNYEKI | || || |.| | || | ||| .. | ..| .| ||| || |. | ||| | . .| | . ..| |.| . |.|.| . NLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL |
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| Kinase | Y47G6A.13.AA | CK1-A | 25-285 | 29 | 5.4e-22 | 74.39 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 25-285 Range on HMM: 1-261/261 Sequence Identity: 29% (79 aa) WRIKALLGKGACGVVYKVEDKNRKGYCAAMKVEYDSEEFDRTLQLEVNVLSKLTDSRDVLKLIDYGKRKLYRYMVTTLCGKDLMALRMKIQRGFNDATAM .|. .| |. | .| . . ..| |.|.| . . | | | | . .. ||. | | || | | | | .| | | . YRLVRKIGSGSFGDIY-LGINITNGEEVAIKMESNKARHPQ-LIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKRRFTMKTVL RVAVFTLYGLKQLHEAGYVHRDVKPGNIMTAANKGRDARVMLLIDFGMARTFVMAGDDGKKKLRPMRRRIPLRGTIRYCSMNVHERKEQGRCDDLVAMIY .| . . .|| ...|||.|| | . || . |||||.|. . | .. | | | ||.|| |.| | || | ||. .| | MLADQMIMRIEYVHEKNFIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKYR---DSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGY SIVYLTLG-LPWSNLKDEKE------IMSMKKSTKDLALFEDLPDELKSIFEYLRTLSYADRPNYEKI ..| .| ||| .| | | || | | |. ...| | | . . |.| . VMMYFNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL |
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| Kinase | Y47G6A.13.AA | CK1-G | 122-285 | 31 | 1.8e-19 | 62.58 | In-house | 97-266 (266) | Show / Hide |
Range on Protein: 122-285 Range on HMM: 97-266/266 Sequence Identity: 31% (55 aa) TAMRVAVFTLYGLKQLHEAGYVHRDVKPGNIMTAANKGRDARVMLLIDFGMARTFVMAGDDGKKKLRPMRRRIPLRGTIRYCSMNVHERKEQGRCDDLVA | . ||. . ....|. . ||||| | . .|..|. .||||||. .. | |. | | . | || || | | | .|| | ||. | TVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYI---DPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEA MIYSIVYLTLG-LPWSNLK--DEKE----IMSMKKSTKDLALFED--LPDELKSIFEYLRTLSYADRPNYEKI . | | ||| || || | |..| .| . .|... .| | |.. . | |. . LGHMFMYFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL |
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| Kinase | Y47G6A.13.AA | S_TKc | 25-293 | 19 | 1.7e-15 | 50.51 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 25-293 Range on HMM: 1-231/231 Sequence Identity: 19% (55 aa) WRIKALLGKGACGVVYKVEDKNRKGYCAAMKVEYDSEEFDRTLQLEVNVLSKLTDSRDVLKLIDYGKRKLYRYMVTTLCGK---DLMALRMKIQRG---- ..| ..|||| |.|||. .|. | |.|. .... |...|.| . . ||.|. . |||. .|. ||. . | .|. YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF -FNDATAMRVAVFTLYGLKQLHEAGYVHRDVKPGNIMTAANKGRDARVMLLIDFGMARTFVMAGDDGKKKLRPMRRRIPLRGTIRYCSMNVHERKEQGRC |. .| ... .. .|. .|. | .|||.|| ||. . ..|||.|| . . || |.. | PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-----------------TTFCGTPWYMAPEVL------GY DDLVAMIYS-----IVYLTLGLPWSNLKDEKEIMSMKKSTKDLALFEDLPDELKSIFEYLRTLSYADRPNYEKIYN-----LLMAAI . . ..| . |. |.. ...... . . ..|.|.. . . . ..|| .. . .. . GKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | Y47G6A.13.AA | Pkinase | 25-176 | 26 | 1.8e-12 | 45.22 | Pfam | 1-162 (293) | Show / Hide |
Range on Protein: 25-176 Range on HMM: 1-162/293 Sequence Identity: 26% (44 aa) WRIKALLGKGACGVVYKVEDKNRKG-YCA-AMKVEYDSEEFDRTLQL--EVNVLSKLTDSRDVLKLIDYGKRKLYRYMVTTLCGK-----DLMALRM-KI ..|. .|.|. |.||| .|. .. .|.. .....|.|. . |. .. .| .. ...|.|. .| . |||. .|.. ||... . . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR QRGF--NDATAMRVAVFTLYGLKQLHEAGYVHRDVKPGNIMTAANKGRDARVMLLIDFGMARTF ...| . .. ... .| ||. .|. | .|||.|| ||. | ||.| ..||| |. | HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVK-ICDFGLAKQF |
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| Kinase | Y47G6A.13.AA | TyrKc | 25-289 | 16 | 5.1e-05 | -141.55 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 25-289
Range on HMM: 1-280/280
Sequence Identity: 16% (51 aa)
WRIKALLGKGACGVVYKVEDKNRKGYCAAMKVEYDSEEFDRTLQLEVNVLSKL-TDSRDVLKLIDYGKRK-------LYRYMVTTLCGK-DLMALRMKIQ
. . || || |.||| . | . | |. .. . . | ....|| . ...|. . . ..|. .. . || | .
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR
RGFNDATAMRVAVFTLYGLKQLHEAGYVHRDVKPGNIMTAANKGRDARVMLLIDFGMARTFVMA------GDDGKKKLRPMRRR-IPLRGTIRYCSMNVH
. .. .. .. | ||. ...||| |.. ..|. .. |||..| .| .|| . .. .| || .. .
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP----IRWMAPECI
ERKEQGRCDDLVAMIYSI---VY---------LTLG-LPWSNL----KDEKEIMSMKKSTKDLALFED--------LPDELKSIFEYLRTLSYADRPNYE
.... |. .|.| |... .. .|.. |. . . .. |||. .| . .|||. .
-----------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFS
KIYNLL
|. ..
EIHECF
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