Gene Y65B4A.9 (Nematode worm)

Y65B4A.9

Species: Nematode worm
Alias: CE22732, aSWK147, Y65B4A.9, Y65B4A_185.a
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: I:-23.03, WormBase Physical Map location: I: 666850-663627

Classification

Group: CK1
Family: Worm6

Sequence

Name Sequence Type Origin Length Description Download
Y65B4A.9.AA Protein Genbank 421 None Fasta, JSON
Y65B4A.9.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 271 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of Y65B4A.9.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Y65B4A.9.AA Worm6 21-288 40 2.7e-139 469.07 In-house 1-279 (279) Show / Hide 
Range on Protein: 21-288
Range on HMM: 1-279/279
Sequence Identity: 40% (114 aa)

YEVTKPLATGTFGSIYKVKRESDGK--FFAVKCEA--LNMKSS-LLRQMSVVLASIHHPSPFFTNIEERGTVPNR-FLFIVMPLYGENLYELMMNTNKDR
..|||....|.||..|||...||.|  .||.|||.   |||.. | ....| .|  ||....|..||.||.|.|| |..|||.|.|.||..|..|.. ||
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRP-DR

KFSMATGLHLAEQTLAAIRDLHRNGFIHRDIKPSHFCIGR---EIDGQHHQVYLLDFGLCKRPRFVKKNDEAEEQMRK-NAIHYRGVVKYASVHAHQGKN
||||.|||..|.|.|.||.|||..||||||.||..|||||   . |..||..|.||||.|.  |....|.. | .... .|...|| |.||....|.|..
KFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCR--RKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQE

LGYKDDMESWWYMVLEFFLGALPWALLNKESEQDVLHLK--RRITAPMVASVWRTTP--ETTAGFFDLLTIIREPKDVAEFV
...|||.|||.||..|...| |||. ........... .  ||..||| . .....|  |... .. .... ........|.
QCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase Y65B4A.9.AA CK1 21-260 27 7.6e-92 311.44 In-house 1-302 (339) Show / Hide 
Range on Protein: 21-260
Range on HMM: 1-302/339
Sequence Identity: 27% (83 aa)

YEVTKPLATGTFG-SIYKV-----KRESDG-----KFFAVKCEAL-NMKSSLLRQMSVVLASI--------------------HHPSPFFTNIEERGTVP
..|.|....| ||  ||||     |.....     ...|.|.|   .|... .... ...  .                    |...|..  ..  | ..
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

NRFLFIVMPLYGENLYELMM-NTNKDRKFSMATGLHLAEQTLAAIRDLHRNGFIHRDIKPSHFCIGR----------EI-DGQHHQVYLLDFGLCKRPRF
... ..||.|.|.|| .|.. |.. .||||| |.|..|.|.| |....|..|||||||||. ||.||          .  ...|.|||..|||...| ..
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARR-KY

VKKNDEA----------EEQMRKN---AIHYRG-VVKYASVHAHQGKNLGYKDDMESWWYMVLEFFLGA--LPWALLNKESE----QDVLHLKRRITAPM
..|...           .  ....   .  .||  ..|.|...|.|| .| .||..||.||..|.. |   |||  ...|..    | | . |. ... .
RDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQ-VEKMKYEFIDEK

VASV
  |.
KMST
Kinase Y65B4A.9.AA TTBKL 21-234 31 9.4e-42 138.77 In-house 1-228 (288) Show / Hide 
Range on Protein: 21-234
Range on HMM: 1-228/288
Sequence Identity: 31% (73 aa)

YEVTKPLATGTFGSIYKVKRESD-GKFFAVKCEALNMKS-SLLRQMSVVLASIHH--PSPFFTNIEERGTVPNRFLFIVMPLYGENLYELM-MNTNKDRK
....| .. | ||..|.|.  .| ....|.| |   .   .   .| | . .     .||.| .. . |  .. . |.|| | |.||  |. |. ||.  
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKD-YNFMVMTLCGPNLQDLRKMMPNKK-R

FSMATGLHLAEQTLAAIRDLHRNGFIHRDIKPSHFCIGREID-GQH-HQVYLLDFGLCKRPRFVKKNDEA-------EEQMRK--N---AIHYRGVVKYA
||  | . .. |.|.|....|..||||||.||. .|.| . . .   . |||.|||...  ....|..|        . .||.  |       || ..|.
FSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMAR--QYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYC

SVHAHQGKNLGYKDDMESWWYMVLEFFLGALPW
|. .|..| .| .||. || ||. |...| |||
SPNMHDRKEQGRHDDLWSWMYMIIELHCG-LPW
Kinase Y65B4A.9.AA TTBK 89-234 39 2.1e-34 118.98 In-house 68-207 (257) Show / Hide 
Range on Protein: 89-234
Range on HMM: 68-207/257
Sequence Identity: 39% (57 aa)

NRFLFIVMPLYGENLYELMMNTNKDRKFSMATGLHLAEQTLAAIRDLHRNGFIHRDIKPSHFCIGREIDGQHHQVYLLDFGLCKRPRFVKKNDEAEEQMR
..| ..|| | |.|| .|  .  .  .||. | | |  | | .|.  |  || ||||||| | .||    .  ..|.|||||    ...  | . |    
DKFNYMVMQLQGKNLADLRRKQPRG-CFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPS-TCRKCYMLDFGLAR--QYT--NACGEVRPP

KNAIHYRGVVKYASVHAHQGKNLGYKDDMESWWYMVLEFFLGALPW
 ..  .|| | |||. ||. ...| .||. |  ||  ||  | |||
REVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVQGQLPW
Kinase Y65B4A.9.AA CK1-A 21-234 31 4.9e-31 106.83 In-house 1-205 (261) Show / Hide 
Range on Protein: 21-234
Range on HMM: 1-205/261
Sequence Identity: 31% (67 aa)

YEVTKPLATGTFGSIYKVKRESDGKFFAVKCEALNMKSSLLRQMSVVLASIHHPSPFFTNIEERGTVPNRFLFIVMPLYGENLYELMMNTNKDRKFSMAT
| . ...  | || ||      .|.  |.| |  . .   |   . |   ..   . . ...  |.  . .  .|| | |  | .|      .|.|.| |
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQG-CVGIPHMRWYGCEKD-YNVMVMDLLGPSLEDLFNFC--KRRFTMKT

GLHLAEQTLAAIRDLHRNGFIHRDIKPSHFCIGREIDGQHHQVYLLDFGLCKRPRFVKKNDEAEEQMRKNAIHYRGVVKYASVHAHQGKNLGYKDDMESW
 | ||.| .. |  .|  .||||||||  | .|  |.    ...|.|||| |. |  .     . .  || .   | ..|||..||.|     .||||| 
VLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMG--IGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLT---GTARYASINAHLGIEQSRRDDMESM

WYMVLEFFLGALPW
 |... | .| |||
GYVMMYFNRGKLPW
Kinase Y65B4A.9.AA CK1-Unique 21-236 24 5.1e-24 80.16 In-house 1-234 (337) Show / Hide 
Range on Protein: 21-236
Range on HMM: 1-234/337
Sequence Identity: 24% (58 aa)

YEVTKPLATGTFGSIYKVKRESDG------KFFAVKCEALNMKSS--LLRQMSVVLASIHHPS------PFFTNIEERGTVPNRFLFIVMPLYGENLYEL
. |.| .  | .|  ..|  . .|      . .. | |   |.    .|     |...|   .        |  ..  . .     .||| . | .. |.
WCVIKHIGYGGYGCVHRVIFVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDFH-QHRDWWWIVMTMHGPSMEEC

MMNTNKDRKFSMATG--------LHLAEQTLAAIRDLHRNGFIHRDIKPSHFCIGREIDGQHHQVYLLDFGLCKRPRFVKKNDEAEEQMRKNAIHYRGVV
 |   . . |..  .        . ...|.| .|.  |  ||.||..||  .| .       |  | ||.| |.|  || .| .      .  . .||. 
CM---MMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQIRQPRPI--TPFRGCK

KYASVHAHQGKNLGYKDDMESWWYMVLEFFLGA--LPWAL
.|..   || . .| .|||||| || .  ...   | | |
DYCPCSCHQCREHGRRDDMESWFYMLYHLVHNTRGLSWKL
Kinase Y65B4A.9.AA CK1-D 113-234 40 1.3e-23 80.08 In-house 89-205 (261) Show / Hide 
Range on Protein: 113-234
Range on HMM: 89-205/261
Sequence Identity: 40% (49 aa)

DRKFSMATGLHLAEQTLAAIRDLHRNGFIHRDIKPSHFCIGREIDGQHHQVYLLDFGLCKRPRFVKKNDEAEEQMRKNAIHYRGVVKYASVHAHQGKNLG
.||||. | | ||.| .. |  .| . ||||||||  | .|  .  . . ||..|||| || |  .          ||     |  .|||.  |||    
HRKFSLKTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMG--LGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLT---GTARYASINTHQGIEQS

YKDDMESWWYMVLEFFLGALPW
 .||.||  |... | .|.|||
RRDDLESLGYVLMYFNRGSLPW
Kinase Y65B4A.9.AA CK1-Unclassified 93-173 47 6.7e-23 64.43 In-house 80-157 (244) Show / Hide 
Range on Protein: 93-173
Range on HMM: 80-157/244
Sequence Identity: 47% (39 aa)

FIVMPLYGENLYELMMNTNKDRKFSMATGLHLAEQTLAAIRDLHRNGFIHRDIKPSHFCIG-REIDGQHHQVYLLDFGLCKR
..|| | |..| .|.   |  ||||. | | .|.| .  |  ||...||||||||  |..| ..  ..|||||. |||| ||
IMVMDLLGPSLEDLFNMCN--RKFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLG--KNHHQVYIIDFGLSKR
Kinase Y65B4A.9.AA CK1 113-173 50 1.5e-20 67.64 In-house 99-158 (271) Show / Hide 
Range on Protein: 113-173
Range on HMM: 99-158/271
Sequence Identity: 50% (31 aa)

DRKFSMATGLHLAEQTLAAIRDLHRNGFIHRDIKPSHFCIGREIDGQHHQVYLLDFGLCKR
.||||. | | .|.| .  |  .| ..||||||||  |..||    ..||||. |||| ||
NRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGR-YGKHCHQVYIIDFGLAKR
Kinase Y65B4A.9.AA Dual 93-224 32 9.1e-19 59.62 In-house 88-213 (282) Show / Hide 
Range on Protein: 93-224
Range on HMM: 88-213/282
Sequence Identity: 32% (44 aa)

FIVMPLYGENLYELMM-NTNKDRKFSMATGLHLAEQTLAAIRDLHRNGFIHRDIKPSHFCIGREIDGQHHQVYLLDFGLCKRPRFVK-KNDEAEEQMRKN
..|| .||  | | .   ...   .|| .    | |.| ||.|||  |..||.|||. | .|  .. .   ||..||.. .   ..  .| .     ||.
YWVMSPYGPSLQEIRRKYIMG--QLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCG--LGMDETTVYMQDFRIVR--KYIDPENKKH-RTARKK

AIHYRGVVKYASVHAHQGKNLGYKDDMESWWYMV
 . . |   ||.      |  | |||.|.| |||
-VKMYGCGRYACRACMMQKDQGRKDDLECWIYMV
Kinase Y65B4A.9.AA Pkinase 21-148 23 3.8e-14 51.09 Pfam 1-137 (293) Show / Hide 
Range on Protein: 21-148
Range on HMM: 1-137/293
Sequence Identity: 23% (33 aa)

YEVTKPLATGTFGSIYKVKRESDGKFFAVKCEALNMKSSLLRQMSV------VLASIHHP--SPFFTNIEERGTVPNRFLFIVMPLYGENLYELMMNT--
|.. ...  |.||. || .. ..|| .|||.  .  ..|  .|  .      ......||    ..   |.     .. . .||.. .  || .|     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----KDHIYMVMEYCEGGLY-VMDLFDY

---NKDRKF--SMATGLHLAEQTLAAIRDLHRNGFIHRDIKPS
    ....|  |. .  . . |.| ..  .|..|.||||.||.
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPE
Kinase Y65B4A.9.AA S_TKc 21-293 14 9.1e-12 -4.38 SMART 1-231 (231) Show / Hide 
Range on Protein: 21-293
Range on HMM: 1-231/231
Sequence Identity: 14% (42 aa)

YEVTKPLATGTFGSIYKVKRESDGKFFAVKCEALNMKSSLLRQMSVVLASIHHPSPFFTNIEERGTVPNRFLFIVMPLYGE---NLYELMMNTNKDRK--
||. ...  |.||. ||..  ..|. .|.|.       ...| ...         |.  .. .       .|..|| . .    .|.... . .. ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK----HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-FSMATGLHLAEQTLAAIRDLHRNGFIHRDIKPSHFCIGREIDGQHHQVYLLDFGLCKRPRFVKKNDEAEEQMRKNAIHYRGVVKYAS--VHAHQGKNLG
 |.  .  ... |.. |.  .|..|.||||.||.   . .       .. . ||||...                   .. |   | .  |         
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-----------------TTFCGTPWYMAPEVL--------

YKDDM-ESWWY----MVLEFFLGALPWALLNKESEQDVLHLKRRITAPMVASVWRTTPETTAGFFDLLT--IIREPK---DVAEFVE-------YDRI
 . .  .. |.    .. |.. |  |.         ..  . ..|               .  . |..     ..|.    . |  .          .
-GYGKCKCDWWSCGCILYEMLCGYPPFP--------QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Y65B4A.9.AA CK1-Unclassified 21-61 34 6.3e-07 16.5 In-house 1-41 (244) Show / Hide 
Range on Protein: 21-61
Range on HMM: 1-41/244
Sequence Identity: 34% (14 aa)

YEVTKPLATGTFGSIYKVKRESDGKFFAVKCEALNMKSSLL
|.|.. . .| || |||..   .....|.| |  | |...|
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQL
Kinase Y65B4A.9.AA CK1-Unclassified 200-234 45 1e-06 15.5 In-house 182-216 (244) Show / Hide 
Range on Protein: 200-234
Range on HMM: 182-216/244
Sequence Identity: 45% (16 aa)

YASVHAHQGKNLGYKDDMESWWYMVLEFFLGALPW
|||. ||.|.  . .||.||  |  . |  | |||
YASINAHLGIEQSRRDDLESLGYVLIYFLKGSLPW
Kinase Y65B4A.9.AA CK1 200-234 45 2e-06 18.04 In-house 182-216 (271) Show / Hide 
Range on Protein: 200-234
Range on HMM: 182-216/271
Sequence Identity: 45% (16 aa)

YASVHAHQGKNLGYKDDMESWWYMVLEFFLGALPW
|||. .|.|.  . .|||||  |. . |  | |||
YASINTHLGIEQSRRDDMESLGYVLMYFLRGSLPW
Kinase Y65B4A.9.AA CK1 21-61 30 4.2e-05 13.75 In-house 1-43 (271) Show / Hide 
Range on Protein: 21-61
Range on HMM: 1-43/271
Sequence Identity: 30% (13 aa)

YEVTKPLATGTFGSIYKVKRESDGKF--FAVKCEALNMKSSLL
|.|.. . .| || ||.... ..|..   |.| |  . | ..|
YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKSKHPQL
Kinase Y65B4A.9.AA Dual 21-53 29 0.033029 3.07 In-house 1-37 (282) Show / Hide 
Range on Protein: 21-53
Range on HMM: 1-37/282
Sequence Identity: 29% (11 aa)

YEVTKPLATGTFGSIYKVKRESD----GKFFAVKCEA
  | . |  | |. .|.| |.|      | ...| |.
WKVVNLLGSGGFRDVYHVHRFSQVNPKNKCYILKTES
Kinase Y65B4A.9.AA CK1-D 21-57 27 0.056111 2.57 In-house 1-37 (261) Show / Hide 
Range on Protein: 21-57
Range on HMM: 1-37/261
Sequence Identity: 27% (10 aa)

YEVTKPLATGTFGSIYKVKRESDGKFFAVKCEALNMK
| . . .  | || ||  .  . .   |.| |..  |
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTK