Gene Y71F9AL.2 (Nematode worm)

Y71F9AL.2

Species: Nematode worm
Alias: Y71F9AL.2, aSWK083, CE25557
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: I:-5.89, WormBase Physical Map location: I: 2915177-2918807

Classification

Group: CK1
Family: TTBKL

Sequence

Name Sequence Type Origin Length Description Download
Y71F9AL.2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 346 Kinase domain by global Sugen HMM Fasta, JSON
Y71F9AL.2.AA Protein Genbank 511 None Fasta, JSON

Protein domain

Protein domains of Y71F9AL.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Y71F9AL.2.AA TTBKL 43-388 35 6.30000000001e-139 467.84 In-house 1-288 (288) Show / Hide 
Range on Protein: 43-388
Range on HMM: 1-288/288
Sequence Identity: 35% (126 aa)

YKLVKKIDEGGFGQVF--KVTKDDKTFYAMKLESNFLEGG-SAIKLELNVLSQLPKN--SVFPALVCGGRRARYQFLVLELLGDNLKVLKSQSTNPEVWS
.. ||.|.|||||||.  ...|| |...||| |.|.|||| | .|.|..||..|..|  ..||...|.|.| .|.|.|..|.|.||..|.... |. ..|
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

DGTWSRVGIQCLFAIKVMHDAGFVHRDIKPSNFAIGFSATSEIRSRRILLFDFGLARKFVRKLP-QASVSVKKDVSKAKSALLKNSSTTKAVAKLRGKPP
||||||.|||||.|.| |||.||.|||.||.|...|... |. |.|...|.|||.||....| . ..                             | |.
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWN-----------------------------G-PI

THRIRDPMKMKKSAGSAAKTKNKDPSQRAMEEIPEHEGYKFRVARPRTDFRGTHQYASPNAHMLIELGRHDDIWSLMYMVAESFVELPWTGCE-ETEVEH
 |...  |......                              |....||||..|.|||.|.  |.|||||.||.|||..| ...||||..| . |.||
-HENKWMMRRPRNF------------------------------RHKAPFRGTTRYCSPNMHDRKEQGRHDDLWSWMYMIIELHCGLPWTNMEDKMEIEH

YKNQSTILRLFSD---EKNPTRLNADMRRQLDEIYSMLKASKYYDSPNYDAVYQFF
 |....  .||.|   .       .|......... .|.. .||| |.|. .|..|
MKKNMKDEDLFKDMPRD-------HDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase Y71F9AL.2.AA CK1 43-384 24 1.4e-96 327.12 In-house 1-339 (339) Show / Hide 
Range on Protein: 43-384
Range on HMM: 1-339/339
Sequence Identity: 24% (98 aa)

YKLVKKIDEGGFG-QVFKVT----KDDKTF-------YAMKLESNFLEGGSAIKLELNVLSQLPKNS---------------------VFPALVCGGRRA
.|.||||.||||| |..||.    || |..       ||||.|..  .|..  ..|. .. .....                       .......|.. 
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

RYQ-FLVLELLGDNLKVLKSQSTNPE-VWSDGTWSRVGIQCLFAIKVMHDAGFVHRDIKPSNFAIGFSAT---------SEIRSRRILLFDFGLAR-KFV
.|  ..|..||| ||  |. |....    |..|| ...||.|.|...|||.||.||||||.||..| .           .. ..|.. ..|||.|| |..
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR

RKLPQASVSVKKDVSKAKSALLKNSSTTKAVAKLRGKPPTHRIRDPMKMKKSAGSAAKTKNKDPSQRAMEEIPEHEGYKFRVARP---RTDFRG-THQYA
.|  .   ..                                                              |  . .. | .|.   .. ||| |  |.
DKDGHNR-WN------------------------------------------------------------G-PRDKTWQHRPPREHKKKKGFRGCTARYC

SPNAHMLIELGRHDDIWSLMYMVAESFVE---LPWTGCE-ETE-----VEHYKNQSTILRLFSDEKNPTRLNAD---MRRQLDEIYSMLKASKYYDSPNY
|.|.|  .|.||.||.||..||..| ..    |||.... |..     ||. | ...   ..|.  .  . . .   ..... .|. .... |||| |.|
SINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKMSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDY

DAV
...
EMI
Kinase Y71F9AL.2.AA Worm6 43-196 35 1.4e-36 127.9 In-house 1-164 (279) Show / Hide 
Range on Protein: 43-196
Range on HMM: 1-164/279
Sequence Identity: 35% (58 aa)

YKLVKKIDEGGFGQVFKVT-KDDKT--FYAMKLESNFLEGGSA-IKLELNVLSQLPKNS--VFPALVCGGRRAR--YQFLVLELLGDNLKVLKSQSTNPE
.|..||| ||||| |.||. |.||.  ..|||.|.   .  .   |.|..||  . .     |. ..  |.  .  . ..|..|.| ||  |.  .    
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRP-DR

VWSDGTWSRVGIQCLFAIKVMHDAGFVHRDIKPSNFAIGF-SATSEIRSRRILLFDFGLAR--KF
  | ||  ...|||| || ..| .||.|||.||.||.||     .   ...| ..|||..|  |.
KFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKY
Kinase Y71F9AL.2.AA TTBK 43-197 34 1.1e-26 91.41 In-house 1-152 (257) Show / Hide 
Range on Protein: 43-197
Range on HMM: 1-152/257
Sequence Identity: 34% (54 aa)

YKLVKKIDEGGFGQVFKVTKDDKT--FYAMKLESNFLEGGSAIKLELNVLSQLPKNSVFPALVCGGRRARYQFLVLELLGDNLKVLKSQSTNPEVWSDGT
 | ||||  |||| ..  .         |.|.||         |.|  || .|         .  ||  .. ..|..|.| ||  |  .       | .|
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVES-AQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPR-GCFSLST

WSRVGIQCLFAIKVMHDAGFVHRDIKPSNFAIGFSATSEIRSRRILLFDFGLARKFV
  |.|.| | .|.  |. || ||||||||||.|  .    . |.. . ||||||...
TLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPS---TCRKCYMLDFGLARQYT
Kinase Y71F9AL.2.AA CK1-Unclassified 43-123 23 5.9e-17 46.59 In-house 1-90 (244) Show / Hide 
Range on Protein: 43-123
Range on HMM: 1-90/244
Sequence Identity: 23% (21 aa)

YKLVKKIDEGGFGQVFKVT-KDDKTFYAMKLESNFLEGGSAIKLELNVLSQLPKNS-------VFPALVCGGRR--ARYQFLVLELLGDNL
|....||. | ||...|.. .......|.|||..  .  . .. |  .. .| ...        .| . . |.    .|...|..||| .|
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSK-HPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSL
Kinase Y71F9AL.2.AA CMGC 43-169 15 1.9e-15 46.34 In-house 1-214 (513) Show / Hide 
Range on Protein: 43-169
Range on HMM: 1-214/513
Sequence Identity: 15% (33 aa)

YKLVKKIDEGGFGQVFKVTK---------------DDKTFYAMK---LESNFLEGGS----------AIKLELNVLSQLP-----------------KNS
|. .||| || .|.|.| .                ... ..|.|   ..  . |..            .  |.  | .|                  .| 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VFPALVCGGRRA----------------RYQFLVLELLGDNL-KVLKSQST-----NPEVWSDGT------------WSRVG------IQCLFAIK--VM
.   . .  ..                 .. .|| |... .| ...|....     .|   |.                          | | ..|   .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HDAG--FVHRDIKPSN
| ..  ..|||.||.|
HSHWGNIIHRDLKPEN
Kinase Y71F9AL.2.AA TTBK 278-325 57 3e-15 50.39 In-house 159-207 (257) Show / Hide 
Range on Protein: 278-325
Range on HMM: 159-207/257
Sequence Identity: 57% (29 aa)

RVARPRTDFRGTHQYASPNAHMLIELGRHDDIWSLMYMVAESFVE--LPW
| .|. . ||||  ||| |||   |.||||| ||| ||  | ||.  |||
RPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVE-FVQGQLPW
Kinase Y71F9AL.2.AA Dual 144-197 37 1.4e-14 45.31 In-house 118-167 (282) Show / Hide 
Range on Protein: 144-197
Range on HMM: 118-167/282
Sequence Identity: 37% (20 aa)

VGIQCLFAIKVMHDAGFVHRDIKPSNFAIGFSATSEIRSRRILLFDFGLARKFV
|.|| | ||.  | .|..||.|||.||..|     . .   . . ||...||..
VAIQMLRAIQDLHSIGYLHRNIKPANFHCGL----GMDETTVYMQDFRIVRKYI
Kinase Y71F9AL.2.AA CK1-A 43-196 29 2e-14 47.25 In-house 1-148 (261) Show / Hide 
Range on Protein: 43-196
Range on HMM: 1-148/261
Sequence Identity: 29% (46 aa)

YKLVKKIDEGGFGQVF-KVTKDDKTFYAMKLESNFLEGGSAIKLELNVLSQLPKNSVFPALVCGGRRARYQFLVLELLGDNLKVLKSQSTNPEVWSDGTW
|.||.||  | || ..  ..  .    |.|.|||       .  |  |  .| .   .| .   |.   |  .|..|||  |  |    .    ..  | 
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKAR-HPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCK--RRFTMKTV

SRVGIQCLFAIKVMHDAGFVHRDIKPSNFAIGFSATSEIRSRRILLFDFGLARKF
  .  | .  |  .|  .|.|||||| || .|          .. | |||||.|.
LMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCN----KLFLIDFGLAKKY
Kinase Y71F9AL.2.AA CK1 43-123 22 3e-13 42.15 In-house 1-91 (271) Show / Hide 
Range on Protein: 43-123
Range on HMM: 1-91/271
Sequence Identity: 22% (21 aa)

YKLVKKIDEGGFGQVFKVTKDDKTF---YAMKLESNFLEGGSAIKLELNVLSQLPK------NSVFPALVCGGRR--ARYQFLVLELLGDNL
|....||..| ||......  ...    .|.|||.|  .  . .. |  .. .| .         .| . . |.     | ..|..||| .|
YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKSK-HPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSL
Kinase Y71F9AL.2.AA S_TKc 43-376 14 9.5e-13 10.03 SMART 1-231 (231) Show / Hide 
Range on Protein: 43-376
Range on HMM: 1-231/231
Sequence Identity: 14% (51 aa)

YKLVKKIDEGGFGQVFKVTKDD-KTFYAMKLESNFLEGGSAIKLELNVLSQLPKNSVFPALVCGGRRARYQFLVLELLGD---NLKV-LKSQSTNP--EV
|....|| .|.||.|.|... . .  .|.|  .        |. |...|..  .      |    .   . ..|.|...    .|.  .|.. ...   .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

WSDGTWSRVGIQCLFAIKVMHDAGFVHRDIKPSNFAIGFSATSEIRSRRILLFDFGLARKFVRKLPQASVSVKKDVSKAKSALLKNSSTTKAVAKLRGKP
 .  .  ..  | . |.. .|. |..|||.||.|  .           .| . ||||||..                                       
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------HIKICDFGLARQL---------------------------------------

PTHRIRDPMKMKKSAGSAAKTKNKDPSQRAMEEIPEHEGYKFRVARPRTDFRGTHQYASPNAHMLIELGR-HDDIWSLMYMVAESFV-ELPWTGCEETEV
                                                | | ||  | .|        |.   |.||.  ...| .. . |.        
------------------------------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-------

EHYKNQSTILRLFSDEKNPTRL---------NADMRRQLDEIYS---MLKASKYY
    .. .....      |  .         . . |    |.       |.  . 
----QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Y71F9AL.2.AA Worm6 281-384 25 2.2e-12 41.01 In-house 175-279 (279) Show / Hide 
Range on Protein: 281-384
Range on HMM: 175-279/279
Sequence Identity: 25% (28 aa)

R-PRTDFRGTHQYASPNAHMLIELGRHDDIWSLMYMVAESFVE-LPWTGCEETEVEH--YKNQSTILR--LFSDEKNPTRLNADMRRQLDEIYSMLKASK
| ..  |||| .||. ..|  .|..| ||. | .||..| .|  ||| .....  ..  .| .   .|  ....  .|.      . ....|  ..   .
RWTACGFRGTVRYAPLACHKGQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPC-----PKEEFNDIMDYIDQYS

YYDSPNYDAV
|.| |.|. .
YWDRPDYKFI
Kinase Y71F9AL.2.AA CK1-Unclassified 154-199 32 1.1e-10 27.79 In-house 119-161 (244) Show / Hide 
Range on Protein: 154-199
Range on HMM: 119-161/244
Sequence Identity: 32% (15 aa)

VMHDAGFVHRDIKPSNFAIGFSATSEIRSRRILLFDFGLARKFVRK
..|  .|.|||||| || .|    .. .. .. . ||||. .....
YLHNKNFIHRDIKPDNFLMGK---LGKNHHQVYIIDFGLSKRYIDM
Kinase Y71F9AL.2.AA CK1-Unique 43-170 22 1.2e-10 33.2 In-house 1-148 (337) Show / Hide 
Range on Protein: 43-170
Range on HMM: 1-148/337
Sequence Identity: 22% (34 aa)

YKLVKKIDEGGFGQVFKVTKDDKT-------FYAMKLESNFLEGG-SAIKLELNVLSQLPKNS-------VFPALVCGGRRARYQFLVLELLGDNLKVLK
..  |.|  ||.| | .| .            |.|| |  |     .  . |.||.  . | .        |. .   .    . ..|. ..| ..  ..
WCVIKHIGYGGYGCVHRVIFVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDFHQHRDWWWIVMTMHGPSMEECC

SQSTN-PEVWS----DGTWSRVGIQCLFAIKVMHDAGFVHRDIKPSNF
    |     .      .  . | |||..| .|| .|| ||..|| |.
MMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNY
Kinase Y71F9AL.2.AA CK1 152-197 36 1.1e-09 29.73 In-house 118-160 (271) Show / Hide 
Range on Protein: 152-197
Range on HMM: 118-160/271
Sequence Identity: 36% (17 aa)

IKVMHDAGFVHRDIKPSNFAIGFSATSEIRSRRILLFDFGLARKFV
| ..|  .|.|||||| || .|    .. .. .. . ||||| ...
IEYVHNKNFIHRDIKPDNFLMGR---YGKHCHQVYIIDFGLAKRYR
Kinase Y71F9AL.2.AA CK1-A 288-327 48 4e-05 13.85 In-house 167-207 (261) Show / Hide 
Range on Protein: 288-327
Range on HMM: 167-207/261
Sequence Identity: 48% (20 aa)

GTHQYASPNAHMLIELGRHDDIWSLMY-MVAESFVELPWTG
||  ||| |||. ||  | ||. |. | |.     .||| |
GTARYASINAHLGIEQSRRDDMESMGYVMMYFNRGKLPWQG
Kinase Y71F9AL.2.AA CK1-Unique 281-315 45 4.5e-05 13.58 In-house 185-219 (337) Show / Hide 
Range on Protein: 281-315
Range on HMM: 185-219/337
Sequence Identity: 45% (16 aa)

RPRTDFRGTHQYASPNAHMLIELGRHDDIWSLMYM
||.| |||.  |..   | . |.|| ||  |. ||
RPITPFRGCKDYCPCSCHQCREHGRRDDMESWFYM
Kinase Y71F9AL.2.AA Dual 43-93 30 0.000207 10.59 In-house 1-53 (282) Show / Hide 
Range on Protein: 43-93
Range on HMM: 1-53/282
Sequence Identity: 30% (17 aa)

YKLVKKIDEGGFGQVFKVTKDDK-----TFYAMKLESNFLEGGSAIKLELNVLSQL
 | |. .  |||. | .| .. .     . |..|.||   |.|   .| | |. |.
WKVVNLLGSGGFRDVYHVHRFSQVNPKNKCYILKTES---EEGEKMMLRLKVEMQV
Kinase Y71F9AL.2.AA CK1-Unclassified 292-314 60 0.00047 7.88 In-house 182-204 (244) Show / Hide 
Range on Protein: 292-314
Range on HMM: 182-204/244
Sequence Identity: 60% (14 aa)

YASPNAHMLIELGRHDDIWSLMY
||| |||  || .| ||  ||.|
YASINAHLGIEQSRRDDLESLGY
Kinase Y71F9AL.2.AA Pkinase 155-170 50 0.000871 14.47 Pfam 124-139 (293) Show / Hide 
Range on Protein: 155-170
Range on HMM: 124-139/293
Sequence Identity: 50% (8 aa)

MHDAGFVHRDIKPSNF
.|. |..|||.||.|.
CHSMGIIHRDLKPENI
Kinase Y71F9AL.2.AA CK1 292-315 54 0.001434 8.39 In-house 182-205 (271) Show / Hide 
Range on Protein: 292-315
Range on HMM: 182-205/271
Sequence Identity: 54% (13 aa)

YASPNAHMLIELGRHDDIWSLMYM
||| |.|. || .| ||  ||.|.
YASINTHLGIEQSRRDDMESLGYV
Kinase Y71F9AL.2.AA Pkinase 43-71 33 0.028016 9.14 Pfam 1-30 (293) Show / Hide 
Range on Protein: 43-71
Range on HMM: 1-30/293
Sequence Identity: 33% (10 aa)

YKLVKKIDEGGFGQVFKVTKDDK-TFYAMK
|....|| .|.||.|.| .. .    .|.|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVK
Kinase Y71F9AL.2.AA Pkinase 281-352 17 4.83523 1.23 Pfam 167-244 (293) Show / Hide 
Range on Protein: 281-352
Range on HMM: 167-244/293
Sequence Identity: 17% (14 aa)

RPRTDFRGTHQYASPNAHM-LIELGRHDDIWSLMYMVAESFV-ELPWTGC-----EETEVEHYKNQSTILRLFSDEKNP
.  |.| ||  |..|  ..   . |.  |.||.  ...| .  ..|. |.      .  . .... ...|.  ......
S-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCS