Gene Y73B6A.1 (Nematode worm)
Y73B6A.1
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| Y73B6A.1.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 219 | Kinase domain by global Sugen HMM | Fasta, JSON |
| Y73B6A.1.AA | Protein | Genbank | 418 | None | Fasta, JSON |
Protein domains of Y73B6A.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | Y73B6A.1.AA | Haspin | 170-386 | 29 | 1.2e-84 | 287.54 | In-house | 1-243 (264) | Show / Hide |
Range on Protein: 170-386 Range on HMM: 1-243/264 Sequence Identity: 29% (71 aa) KVEKLGQGNHGTIFKVRWNGRRAAMKVLHVPGEIS-------------ADTAKDEITVMKKVGSAVFRKKNPSFLEFLGAYLVEGHSKTDPKLQFKNKNG ...|.|.|..|..|.|.|||.. .||....... . .|.|..||..|||.|. .|...|.|..|.|.. |... ....|...|... NCKKIGEGCYGEVFSVTWNGKEVVMKIIPIHWSCCKYYGEYCGEHQQTNDEALNEIIIMKKMGKLSHRNMCPNFPNFCGMCVVTQVPGKCCKKLNKMWDH HPLPE----------KAQFVAIFMELVEGGRSIGDF--PFKTDNERKSFVCQLVVGLMTAQKELGFSHGDLSVDNTIVT-KTKLRTVAYILEGKAVKLKT .. .. |.....|.... .|||.. .| .|.|.|...|..||||.....|..|..|.|.|| ..|.... |||.....|...||..|.|. YCYTHHSENDRPDFFKKNQLHIHWIMEYGGRPLDNFRWKFNTCNQCISIMCQLVMSMYIAKDEMQFWHNDLHWGNVLIKRKTKKKWLHYTMDGKTIKIKS SGVLLKIIDYGKSECSSDNKASTSFEDSDYTKLRNHAMDVFKV .||...|||..||.|..|||..... ..|.|. .......|.| HGVMVTIIDFCKSRCGKDNKKIYWDWKNDETMFEQFWDYQFDV |
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| Kinase | Y73B6A.1.AA | TKL-Unique | 170-217 | 27 | 1.4e-07 | 22.94 | In-house | 1-51 (290) | Show / Hide |
Range on Protein: 170-217 Range on HMM: 1-51/290 Sequence Identity: 27% (14 aa) KVEKLGQGNHGTIFKVRWNGRRAAMKVLHV---PGEISADTAKDEITVMKK ..|.|.| |...|. |.| |.|..|. . .. .. ..|...||| FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKK |
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| Kinase | Y73B6A.1.AA | STE | 169-276 | 17 | 1.3e-05 | 15.92 | In-house | 1-122 (359) | Show / Hide |
Range on Protein: 169-276 Range on HMM: 1-122/359 Sequence Identity: 17% (24 aa) GKV-EKLGQGNHGTIFKVRWN-----------------GRRAAMKVLHVPGEISADTA------------KDEITVMKKVGSAVFRKK-NPSFLEFLGAY . ||.|.|. || .| . . |.. |.|.... . . | ... ..| . .. | ...|.| WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY LVEGHSKTDPKLQFKNKNGHPLPEKA-QFVAIFMELVEGG ..||| .|. . . |.||...|| FKEGHN-----------------HKNDDELWICMEYMDGG |
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| Kinase | Y73B6A.1.AA | S_TKc | 168-407 | 12 | 1.4e-05 | -95.14 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 168-407 Range on HMM: 1-231/231 Sequence Identity: 12% (37 aa) TGKVEKLGQGNHGTIFKVRWNG--RRAAMKVLHVPGEISADTAKDEITVMKKVGSAVFRKKNPSFLEFLGAYLVEGHSKTDPKLQFKNKNGHPLPEKAQF ...|.|.| |. .|.|... |. |.|... .... || ..|| . | ..... .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK--------HHPNIVKLYDVFQD------------------------DH VAIFMELVEG-GRSIGDFPFK----------TDNERKSFVCQLVVGLMTAQKELGFSHGDLSVDNTIVTKTKLRTVAYILEGKAVKLKTSGVLLKIIDYG . ..||...| . . |. | . . .....|.. .| . |. | || .| ... .||.| | LYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE----------------------HIKICDFG KSECSSDNKAST------------S---------------------FEDSDYTKLRNHAMDVFKVPGLKALADAVNNYDEE--------H-------ASW . . | |. .. .. .. . | .| . . ..| | . | LARQL-TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPW Y F |
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| Kinase | Y73B6A.1.AA | LISK | 173-198 | 28 | 1.4e-05 | 13.91 | In-house | 1-28 (296) | Show / Hide |
Range on Protein: 173-198 Range on HMM: 1-28/296 Sequence Identity: 28% (8 aa) KLGQGNHGTIFKVRWN--GRRAAMKVLH ..|.|. | ..|.... |. |.| .| EIGKGFFGKVYKGTHRQTGQVMAIKMIH |
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| Kinase | Y73B6A.1.AA | TKL | 174-217 | 15 | 2.7e-05 | 15.06 | In-house | 1-79 (364) | Show / Hide |
Range on Protein: 174-217 Range on HMM: 1-79/364 Sequence Identity: 15% (12 aa) LGQGNHGTIFKVRWNG----------RRAAMKVLHVPG-------------------------EISADTAKDEITVMKK .|.| |...| .|.| . |.|.... |.| . | .| . IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMM |
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| Kinase | Y73B6A.1.AA | SFK-Src | 172-217 | 44 | 5.1e-05 | 10.17 | In-house | 5-50 (259) | Show / Hide |
Range on Protein: 172-217 Range on HMM: 5-50/259 Sequence Identity: 44% (21 aa) EKLGQGNHGTIFKVRWNGRRA-AMKVLHVPGEISADTAKDEITVMKK .|||.| | ..| |||. . | | | || .||. | |||| KKLGSGQFGDVWKGRWNNTTEVAVKTLK-PGAMSAEEFLQEAQVMKK |
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| Kinase | Y73B6A.1.AA | SrcA | 171-218 | 36 | 0.000231 | 9.18 | In-house | 4-51 (250) | Show / Hide |
Range on Protein: 171-218 Range on HMM: 4-51/250 Sequence Identity: 36% (18 aa) VEKLGQGNHGTIFKVRWNGR-RAAMKVLHVPGEISADTAKDEITVMKKV .|||| | .. ||| . |.| | || .| .. .| .|||. ERRLGQGCFGEVWMGTWNGTTKVAIKTLK-PGTMSPEAFLEEAQIMKKL |
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| Kinase | Y73B6A.1.AA | Src | 171-218 | 38 | 0.000599 | 9.25 | In-house | 4-51 (255) | Show / Hide |
Range on Protein: 171-218 Range on HMM: 4-51/255 Sequence Identity: 38% (19 aa) VEKLGQGNHGTIFKVRWNG-RRAAMKVLHVPGEISADTAKDEITVMKKV ..|||||. | .. ||| | |.| || | . |. .|||. CRKLGQGQFGEVWMGYWNGNTKVAVKTLK-PGTMSPEAFLQEAQIMKKL |
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| Kinase | Y73B6A.1.AA | MOS | 168-197 | 26 | 0.000655 | 8.61 | In-house | 1-30 (299) | Show / Hide |
Range on Protein: 168-197
Range on HMM: 1-30/299
Sequence Identity: 26% (8 aa)
TGKVEKLGQGNHGTIFKVRWNGRRAAMKVL
. .|.| |...| . ||. | |..
VCLCQMIGRGGFGSVWKAQYCGRPVAVKQV
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| Kinase | Y73B6A.1.AA | RAF | 171-217 | 32 | 0.000858 | 7.84 | In-house | 4-54 (282) | Show / Hide |
Range on Protein: 171-217 Range on HMM: 4-54/282 Sequence Identity: 32% (17 aa) VEKLGQGNHGTIFKVRWNGRRAAMKVLHV----PGEISA-DTAKDEITVMKK .. |.| ||... .| | .| |.| | | .. | .|.|. |.|| MTRIGSGSFGTVYRGHWHG-DVAVKMLNVNDPTPEQMQADVFFKNEVAVYKK |
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