Gene ZC504.3 (Nematode worm)

ZC504.3

Species: Nematode worm
Alias: ZC504.3, CE03811, aSWK167
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: X:1.95, WormBase Physical Map location: X: 10423813-10420437

Classification

Group: CMGC
Family: CDK
Subfamily: PITSLRE

Sequence

Name Sequence Type Origin Length Description Download
ZC504.3.AA Protein Genbank 763 None Fasta, JSON
ZC504.3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 297 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of ZC504.3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ZC504.3.AA PITSLRE 399-695 63 1.5e-227 762.24 In-house 1-295 (295) Show / Hide 
Range on Protein: 399-695
Range on HMM: 1-295/295
Sequence Identity: 63% (191 aa)

YVILNVIAEGTYGEVFRGKNTRTDEVVALKRFKME--KEKEGFPITALREINMLLKAGAHENIVNVKEILVGSTKTEVYMAMEYVEHDVKSLIDKMRSRN
...||.|.|||||.|.|.|..||||.|||||.|||  |||||||||.||||||.|.|..|.||||||||..||.....||.|||||||.|||...|..||
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

QRFKTGQQKTLMSQLLSGIEHMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRMKLTPIVVTLWYRSPELLLEPKTYSTPVDMWSIGC
|.||.|..|.||.|||.|.||||..||.||||||||||.||.|||||.|||||||||..     ....||.|||||||.|||||..|.|||||||||.||
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSP-----IKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGC

IMAEFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWPDIKELKVWNMVE-FPPVKPGQLRRIFKGEKLVNETGFDLLNGMLCLNPANRLTASEALQHDWF
|.||||.|||.|||.||..|...||..||||||.|||...||..|.|.. ||......||..|..|.....|||||||.||..||.||.|||.||.|.||
IFAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase ZC504.3.AA CDK 399-695 39 3.2e-161 519.68 In-house 1-284 (284) Show / Hide 
Range on Protein: 399-695
Range on HMM: 1-284/284
Sequence Identity: 39% (131 aa)

YVILNVIAEGTYGEVFRGKNTRTD-----EVVALKRFKMEK-----EKEGFPITALREINMLLKAGAHENIVNVKEILVGSTKT---------EVYMAME
| .|. | |||||.|.......|.     ..||||...||.     |||||||||.|||..| .   |.|||..... .....           .|| .|
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

YVEHDVKSLIDKMRSRNQRFKTGQQKTLMSQLLSGIEHMHKLWILHRDLKTSNLLISHSGI-----LKIADFGLAREYGEA--RDIEKRMKLTPIVVTLW
|..|| |...|              |..| |||.|....|. ||.|||||..|.||.. |.     ||||||||||..|     . |.....|. |||||
YMDHDLKKYMD-------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMS-EPNRTYTHEVVTLW

YRSPELLLEPKTYS--TPVDMWSIGCIMAEFIM---MKPMFQGDSEPNQVHQIFQMMGTPTEQIWPDIKELKVWNMVEFPPVKPGQLRRIFKGEKLVNET
||.|||||  |.||  ||.||||.|||.||...    ||.|.|||| .| . ||...|||||..||....|  .                          
YRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY--------------------------

GFDLLNGMLCLNPANRLTASEALQHDWF
  ||||.|||..|..|..|..||||..|
--DLLNKMLCYDPKKRISAEQALQHPYF
Kinase ZC504.3.AA CMGC 399-695 25 6.4e-133 439.52 In-house 1-513 (513) Show / Hide 
Range on Protein: 399-695
Range on HMM: 1-513/513
Sequence Identity: 25% (131 aa)

YVILNVIAEGTYGEVFRGKNTRTD--------------EVVALKRFK---MEK------EKEGFPITALREINMLLKAG---------------AHEN-I
| |...| |||||.|......||.              |.||.|..|   .|       ||.||||.||||| .| .                  |.| |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VNVKEILVGST---------------KTEVYMAMEYVEHDVKSLIDKMRS-----RNQRFKTGQ------------QKTLM------SQLLSGIE--HMH
|. ..|.. .                  ..|. .||..|| . .|....      |.. ..  .             | .|       |.| |..  ..|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

KLW--ILHRDLKTSNLLISHS--------------------GILKIADFGLAREYGEA-----------------RDIEKRMKLTPIVVTLWYRSPELLL
. |  |.||||| .|.||.|                     |.|||.|||||| |..                   | .... .|. |||.|||.||.||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDD-KPNRPYTHYVVTRWYRAPEILL

EPKTYS---------TPVDMWSIGCIMAEFIMM--------KPMFQGDSE-----------PNQVHQIFQMMGTPT---------------EQIWPDIKE
  | |.         ||.||||.|||.|| ..         ||.|.|.||            .| ..||...||||               |..||....
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

LKVWNM-------------------------VEFPPVKPGQLRRIFKG--------------------------------EKLVNETGFDLLNGMLCLNP
|  .|.                           ||...|  ....|..                                .|. .. ..|||..||...|
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

ANRLTASEALQHDWF
..|.||..||||..|
DKRITAEQALQHPYF
Kinase ZC504.3.AA CDC2 399-695 42 2.2e-127 393.72 In-house 1-301 (301) Show / Hide 
Range on Protein: 399-695
Range on HMM: 1-301/301
Sequence Identity: 42% (131 aa)

YVILNVIAEGTYGEVFRGKNTRTDEVVALKRFKMEKEKEG--FPITALREINMLLKAGA-HENIVNVKEILVGSTKTEVYMAMEYVEHDVKSLIDKMRSR
|  .. | |||||.|...|...|...||||... | | ||  .| ||.|||  .||.   |.|||  .....      .||  ||...| | . |.  . 
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREI-SCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPK

NQRFKTGQQKTLMSQLLSGIEHMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRMKLTPI--VVTLWYRSPELLLEPKTYSTPVDMWS
|. .     | .| |.|.|... |   |.||||| .|.||. .| .|||||||||  |   .     ..|.   |||||||.||.||  |.|||||||||
NKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIR-----TYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWS

IGCIMAEF---IMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWPDIKELKVWNMVEFPPVKPGQLRRIFKG------EKLVNETGFDLLNGMLCLNPANRL
||||.||.   .. ||.|.||||  |  .||...|||.||.||....|. ...  ||  || .|..|..       .  ....|.|||. ||...|..|.
IGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNT-FPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRI

TASEALQHDWF
.| ||||| .|
SAKEALQHPYF
Kinase ZC504.3.AA CRK7 399-695 39 9.79999999999e-106 357.58 In-house 1-343 (343) Show / Hide 
Range on Protein: 399-695
Range on HMM: 1-343/343
Sequence Identity: 39% (138 aa)

YVILNVIAEGTYGEVFRGKNTRTDEVVALKRFKMEKE---KEGFPITALREINMLLKAGAHENIVNVKEILVG--------STKTEVYMAMEYVEHDVKS
| ... | ||||| |   ||..| | ||||...|. |   |||||||| |||  .|.   |.|||| ||| .         ..|  .||  ||. ||   
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREI-KILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMG

LIDKMRSR-NQRFKTGQQKTLMSQLLSGIEHMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRMKLTPIVVTLWYRSPELLLEPKTY-
|   ..|   . |  .| | .| ||| |.. .||  .||||.| ||.|.  .|..||||||||| |      ||| ..|  |.||||| |||||  . | 
L---LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSE---EKRRPYTNRVITLWYRPPELLLGEERYT

-------------------------------------STPVDMWSIGCIMAEFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWPDIKELKVWNMVEFPP
                                      . .|||| |||..|    ||.|||  |. |   |.. .|.|. . ||.. .|  ||.  . |
EQHILKELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNT--MKP

VK--PGQLRRIFK-GEK--LVNETGFDLLNGMLCLNPANRLTASEALQHDWF
 .     ||  |   .|  .  .  .||| .||||.|  | ||.|.||||||
KRQYNRRLREEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase ZC504.3.AA CDK5 399-695 40 3.5e-102 323.7 In-house 1-287 (287) Show / Hide 
Range on Protein: 399-695
Range on HMM: 1-287/287
Sequence Identity: 40% (122 aa)

YVILNVIAEGTYGEVFRGKNTRTDEVVALKRFKMEKEKEGFPITALREINMLLKAGAHENIVNVKEILVGSTKTEVYMAMEYVEHDVKSLIDKMRSRNQR
|  .. | ||||| |....|  | |.||||| ... | || | ||.|||  |||   |.|||    ..    |    .  |..  | |  .|..      
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREI-CLLKELKHKNIVRLHDVIHSEKK--LTLVFEFCDQDLKKYMDSCNG---E

FKTGQQKTLMSQLLSGIEHMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRMKLTPIVVTLWYRSPELLLEPKTYSTPVDMWSIGCIM
      | .| ||| |..  |.  .||||||  ||||.  |.|| ||||||| .|    |  |   .  ||||||| |  |.  |.|||..||||.|||.
MDMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFG----IPVRC-YSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIF

AEFI-MMKPMFQGDSEPNQVHQIFQMMGTPTEQIWPDIKELKVWN--MVEFPPVKPGQ-LRRIFKGEKLVNETGFDLLNGMLCLNPANRLTASEALQHDW
|| .   .|.| | .. .|  .||..||||.|  || | .|  ..  ....|.  . | .  | ..    .|.| |||..|| .||. |..| .||.| .
AEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPK---LDEKGMDLLQKMLQCNPNQRISAKAALHHPY

F
|
F
Kinase ZC504.3.AA CDK7 399-695 36 1.2e-99 266.08 In-house 1-288 (288) Show / Hide 
Range on Protein: 399-695
Range on HMM: 1-288/288
Sequence Identity: 36% (110 aa)

YVILNVIAEGTYGEVFRGKNTRTDEVVALKRFK----MEKEKEGFPITALREINMLLKAGAHENIVNVKEILVGSTKTEVYMAMEYVEHDVKSLIDKMRS
| ..  | ||... |...  . |...|| |. |     .  | |   ||.|||  .|.   |.|...   |.    |. ... ... . |    |   . 
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREI-KILQEMQHDNVIGLIDIFM--HKSNIQLVFDFMDWDLEVVI---KD

RNQRFKTGQQKTLMSQLLSGIEHMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRMKLTPIVVTLWYRSPELLLEPKTYSTPVDMWSI
    ..    |  | ..| |.|..|. ||||||||  |||..  |.|||||||||| ||    |     .|. ||| |||.||||   . | | |||||.
KSIILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRI-----YTHQVVTRWYRAPELLFGARHYGTGVDMWSV

GCIMAEFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWPDIKELKVWNMV-EFPPVKPGQLRRIFK--GEKLVNETGFDLLNGMLCLNPANRLTASEALQ
|||.|| .   | . |||.  |   ||| .|||||. ||.. ...  .   .||.     || ||   .. |.     ||. ||. .|| .|.|....|.
GCIFAELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLL-----DLMCGMWTMNPCKRWTCTQCLK

HDWF
.. |
MPYF
Kinase ZC504.3.AA S_TKc 399-695 27 7.2e-95 322.39 SMART 1-231 (231) Show / Hide 
Range on Protein: 399-695
Range on HMM: 1-231/231
Sequence Identity: 27% (84 aa)

YVILNVIAEGTYGEVFRGKNTRTDEVVALKRFKMEKEKEGFPITALREINMLLKAGAHENIVNVKEILVGSTKTEVYMAMEYVEH---DVKSLIDKMRSR
| ||..| .|..|.|.......|...||.|. |         ....|||..| |   |.|||. ... .    ...|| |||...   |....|.|....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRH

NQR--FKTGQQKTLMSQLLSGIEHMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRMKLTPIVVTLWYRSPELLLEPKTYST-PVDMW
  |  |   . . .| |.....|..|...|.||||| .|.|...   .||.||||||..            | ...|.||..||.|     |.. ..|.|
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------TTFCGTPWYMAPEVL----GYGKCKCDWW

SIGCIMAEFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWPDIKELKVWNMVEFPPVKPGQLRRIFKGEKLVNETGFDLLNGMLCLNPANRLTASEALQ-
|.|||..|..  .| |.      |....|...|                                        . . |.....|. .|..|.|| |||| 
SCGCILYEMLCGYPPFP------QMQMMFKKIG---------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQD

------HDWF
      | ||
EWDIKCHPWF
Kinase ZC504.3.AA CDK10 399-695 43 1.5e-91 310.49 In-house 1-285 (285) Show / Hide 
Range on Protein: 399-695
Range on HMM: 1-285/285
Sequence Identity: 43% (128 aa)

YVILNVIAEGTYGEVFRGKNTRTDEVVALKRFKMEKEKEGFPITALREINMLLKAGAHENIVNVKEILVGSTKTEVYMAMEYVEHDVKSLIDKMRSRNQR
.  || . ||||| |.| . .|.||.||||. .|.|||.| || .|||| |||.   |||||...|. ||     ... |.| | |. ||.| |    | 
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREI-MLLIQCRHENIVELHEVVVGQHLDSIFLVMQYCEQDLASLLDNM---PQP

FKTGQQKTLMSQLLSGIEHMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRMKLTPIVVTLWYRSPELLLEPKTYSTPVDMWSIGCIM
|   | | .| |.| |.  .|. ...||||| ||||..  | .|.||||||| ||      | |  || .|||||| |||||  .|  | .||| .|||.
FTETQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVP---VKPM--TPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCIL

AEFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWPDIKELKVWNMVEFPPVKPGQLRRIFKGEKLVNETGFDLLNGMLCLNPANRLTASEALQHDWF
.| .. ||.. | ||  |.  | ...||| |.|||   .| . .           |.  |   ... ..|  ||| ..  ||  | || |.|.  .|
GELLVHKPLMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYNNLKHKF---HWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF
Kinase ZC504.3.AA CDK4 399-695 37 3.5e-85 289.32 In-house 1-290 (290) Show / Hide 
Range on Protein: 399-695
Range on HMM: 1-290/290
Sequence Identity: 37% (115 aa)

YVILNVIAEGTYGEVFRGKNTRTDEVVALKRFKMEKEKE--GFPITALREINML--LKAGAHENIVNVKEILVGSTKTE----VYMAMEYVEHDVKSLID
|. .. | || || |.|   . |   ||||. .   . |  | |.  .||| ..  |.. .| |||  ...   .        . | .| .. | . ..|
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD

KMRSRNQR--FKTGQQKTLMSQLLSGIEHMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRMKLTPIVVTLWYRSPELLLEPKTYSTP
|.     .    . . | .| |||.|..  |   | |||||  |.|.. .| .|.|||||||.|.        |.|||.|||||||.|| ||   .| ||
KCP----PPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSF------QMALTPVVVTLWYRAPEVLLQ-SYYNTP

VDMWSIGCIMAEFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWP-DIKELKVWNMVEFPPVKPGQLRRIFKGEKLVNETGFDLLNGMLCLNPANRLTAS
|||||.|||.||    .| | | || .| |.|| .||.|.|. || |.    .     ||. .| ... .        . | |||. ||| |.. |..| 
VDMWSVGCIFAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDV----SLPWDHFPQRHPRPFKDFCPH---MCKQGDDLLQKMLCYNHHKRMSAY

EALQHDWF
..|||..|
QCLQHPYF
Kinase ZC504.3.AA Pkinase 399-695 30 2.5e-84 291.24 Pfam 1-293 (293) Show / Hide 
Range on Protein: 399-695
Range on HMM: 1-293/293
Sequence Identity: 30% (94 aa)

YVILNVIAEGTYGEVFRGKNTRTDEVVALKRFKMEKEKEGFPITALR--EINMLLKAGAHENIVNVKEILVGSTKTEVYMAMEYVEHDVKSLIDKM----
|.|. .| .|..|.|.....  | ..||.|..| ..||.....|..|  || ....   |.|||  ...     |...|| |||.|.... ..| .    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLY-VMDLFDYIS

RSRNQRF--KTGQQKTLMSQLLSGIEHMHKLWILHRDLKTSNLLISHSGIL----KIADFGLAREYGEARDIEKRMKLTPIVVTLWYRSPELLLEPKTYS
..|. .|     . |  | |.|.|.|..|. .|.||||| .|.||.. | .    ||.|||||. .     . .   .| ...|.||..||.... . |.
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYG

TPVDMWSIGCIMAEFIMMKPMFQGD----SEPNQVHQIFQMMGTPTEQIWPDIKELKVWNMVEFPPVKPGQLRRIFKGEKLVNETGFDLLNGMLCLNPAN
..|||||.|||..|..  .| |.|.    .  .| . |.. ||.|..  ||   .    . . . . .     . ..  ....|.. |.....||..|. 
PKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-----F-HWTFHNWSEECKDFIKWCLCKDPKK

RLTASEALQHDWF
|.|| ..|||.||
RPTAEQILQHPWF
Kinase ZC504.3.AA CDK9 399-695 35 6.3e-78 265.19 In-house 1-340 (340) Show / Hide 
Range on Protein: 399-695
Range on HMM: 1-340/340
Sequence Identity: 35% (123 aa)

YVILNVIAEGTYG-----------EVFRGKNTRTDEVVALKRFKMEKEKEGFPITALREINML--LKAGAHENIVNVKEI-------LVGSTK-TEVYMA
|  |. |  ||.|           |||. .  ..  .||.|.  || ||||||||||||| ||  ||   |||.||  ||         ..     .|. 
YEKLAKIGQGTFGQVLQGRKSRNSEVFKARHKKNKRMVAMKKVLMENEKEGFPITALREIKMLQLLK---HENVVNLIEICRTKATAYNRYKDRATFYLV

MEYVEHDVKSLIDKMRSRNQRFKTGQQKTLMSQLLSGIEHMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRM-KLTPIVVTLWYRSP
... |||   |   |   | .|  |  |..| .|..|   .|.  |||||.|  | ||.  |||| ||||||| .  ..   .     |  ||||||| |
FDFCEHDLAGLLSNM---NVKFSLGHIKKMMQHLMNGLYYIHRNKILHRDMKAANVLITKDGILKLADFGLARAFSQPKNDAPNRPLYTNRVVTLWYRPP

ELLLEPKTYSTPVDMWSIGCIMAEFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWPDIKELKVWNMV------EFPPVK----PGQLRRIFK-------
||||    | .|.|||  ||||||     |  ||. |  |   | |. |  |...|| . ..  || .      | |  .    . ...   |       
ELLLGDRNYGPPIDMWGAGCIMAEMWTRSPIMQGNTEQHQLQLISQLCGSITPDVWPNCENMELWNKMSSEPNSELPKGQKRKVKDRMKNYMKFDAPDSK

----------GEKLVNETGFDLLNGMLCLNPANRLTASEALQHDWF
           .    ... .|.. .| . |. |... ||| ||||
TDPFGKNVKQHDSATDQQACHLIDKLLNIDPKKRMDSDEALDHDWF
Kinase ZC504.3.AA TyrKc 399-695 20 3.3e-13 -9.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 399-695
Range on HMM: 1-280/280
Sequence Identity: 20% (66 aa)

YVILNVIAEGTYGEVFRGKNTRTDEVVALKRFKMEKEKEGFPITALREINMLLKAG-AHENIVNVKEILVGSTK-----TEVYMAMEYVEH-DVKSLIDK
 . . .. || .|||..|. .   . || |  | ..         .||.... | |  |.|||.   . . .         ... |||..| | |. . |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

MRSRNQRFKTGQQKTLMSQLLSGIEHMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGEA-----RDIEKRMK---LTPIVVTLWYRSPELLLEPK
 | .   ... .    . |  .| |. |.  . |||| . | |... .. ||.||||.|. ..      ..  .|.|    .  .. .   .|| .   .
HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYG

TYSTPVDMWSIGCIMAEFIMMKPMFQGD-----SEPNQVHQI---FQMMGTPTEQIWPDIKELKVWNMVEFPPVKPGQLRRIFKGEKLVNETGFDLLNGM
...|  | || |  | |      .   .      .. .|..      .|  | .   | .                      |       .  ...    
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MS---------------------F---VCCPDEMYQIMKQC

LCLNPANRLTASEALQHDWF
   .|..| | ||   |. |
WHEDPEDRPTFSEI--HECF
Kinase ZC504.3.AA Pkinase_Tyr 399-550 28 6.5e-12 40.98 Pfam 1-159 (270) Show / Hide 
Range on Protein: 399-550
Range on HMM: 1-159/270
Sequence Identity: 28% (47 aa)

YVILNVIAEGTYGEVFRGKNT----RTDEVVALKRF---KMEKE--KEGFPITALREINMLLKAGAHENIVNVKEILV--GSTKTEVYMAMEYVEHDVKS
 ... .. || .|||..|. .     |.  || |      |...  .| |    .||.... . | |.|||.   . .  |  . ..|. |||..|   .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDF----MREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHG--D

LIDKMRSR---NQRFKTGQQKTLMSQLLSGIEHMHKLWILHRDLKTSNLLISHSGILKIADFGLAR
| |  |..   .|.... .      |  .| |. .   . |||| . | |...... ||.||||||
LLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR