Gene HRR25 (Bakers Yeast)

HRR25

Species: Bakers Yeast
Alias: HRR25
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: CK1
Family: CK1
Subfamily: CK1-D

Sequence

Name Sequence Type Origin Length Description Download
HRR25.AA Protein Refseq_NP 494 `Similar to YCK1 and YCK2, two other casein kinase I isoforms; found primarily in nucleus; may be involved in DNA-damage repair; Hrr25p [Saccharomyces cerevisiae]` Fasta, JSON
HRR25.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 259 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of HRR25.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase HRR25.AA CK1 9-267 65 3.3e-201 674.73 In-house 1-271 (271) Show / Hide 
Range on Protein: 9-267
Range on HMM: 1-271/271
Sequence Identity: 65% (177 aa)

FRIGRKIGSGSFGDIYHGTNLISGEE--VAIKLESIRSRHPQLDYESRVYRYLSG------GVGIPFIRWFGRE--GEYNAMVIDLLGPSLEDLFNYCHR
.|.|||||.|||||||.|.|. .|||  ||||||...|.||||.||...|..| |      ..||| ..|.|.|  |.||.||.||||||||||||.|.|
YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFCNR

RFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGV-GRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLE
.|| |||.|.| || .||.|.| ..||||||||||||||. |... .|..|||||.|.||| .||.||||||||.|||||||||.|||||||||||||.|
KFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDME

SLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSG-LPLEFQEYMAYCKNLKFDEKPDYL
||||||.||..|||||||||| ||||||..|||||....||.||.| .| ||..|. ||..|.|.||||| 
SLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase HRR25.AA CK1-D 9-269 73 9.3e-201 673.23 In-house 1-261 (261) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-261/261
Sequence Identity: 73% (193 aa)

FRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSFKTVIML
.|||||||||||||||||||....||||||||.|...||||..||..|....||.|||.|||.|.||.||.||.||||||||||||||||.||.|||.||
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHRKFSLKTVLML

ALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYVLIYFCK
|.||.|||.|||.|.||||||||||||||.|.||..|..|||||.|.|||..||.||||||||.|||||||||.|||.|||||||||||||||||.||..
ADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNR

GSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSGLPLEFQEYMAYCKNLKFDEKPDYLFL
||||||||||.||.|||.||.|||......|||.|.|.|||.||.||.|||||.||||..|
GSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase HRR25.AA CK1-Unclassified 9-241 63 3.4e-187 557.47 In-house 1-244 (244) Show / Hide 
Range on Protein: 9-241
Range on HMM: 1-244/244
Sequence Identity: 63% (154 aa)

FRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGV-------GIPFIRWFGRE--GEYNAMVIDLLGPSLEDLFNYCHRR
.|...|||.||||.||...|. ..||||||||.  |.||||.|| ....|| .|        ||| . |.|.|  |.|| || ||||||||||||.| |.
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCNRK

FSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMG-VGRRGSTVHVIDFGLSKKYRDF-NTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLE
|| ||| |.| ||  ||.|.| ..||||||||||||||  |..  .|. |||||||.|.|  .|..||||||||.|||||||||.|.|||||||||||||
FSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDLE

SLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLC
||||||||| |||||||..|| .||.||..|||.|....|| ||
SLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC
Kinase HRR25.AA CK1-A 9-269 67 1e-158 533.55 In-house 1-261 (261) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-261/261
Sequence Identity: 67% (175 aa)

FRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSFKTVIML
.|. |||||||||||| | |. .|||||||.|| . ||||| ||..||| |.|.|||| .||.|.| .||.||.||||||||||||.|.|||..|||.||
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKRRFTMKTVLML

ALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYVLIYFCK
| ||  || |.| ..||||||||||||||.||    ...|||||.||||| .|..|||||| | |||||||||.| |||||||||||.||.|||..|| .
ADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNR

GSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSGLPLEFQEYMAYCKNLKFDEKPDYLFL
|.|||||.|| ||||||..| |||. ...| || | | ||  ||.||.||.|.|.|||..|
GKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase HRR25.AA CK1-G 9-269 53 4.6e-147 494.87 In-house 1-266 (266) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-266/266
Sequence Identity: 53% (141 aa)

FRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGV-GIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSFKTVIM
.|.|.||| |.|| .. |.|.. .| ||||.| ..|| |||  | | |. |.| . ||| . .|| .| ||.||.|||||||||||. | |.|| |||.|
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFDWCDRKFSVKTVCM

LALQMFCRIQYIHGRSFIHRDIKPDNFLMG--VGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYVLIY
.| ||  |..|.| .. | ||.|||||| |    ..  ..|.||||. |.|.| .| .|||||| ||||||||| |.||||| |||||||.|.|| . .|
VAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMFMY

FCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSG--LPLEFQEYMAYCKNLKFDEKPDYLFL
|  |||||||||| . |..|..| ..| .. .| || .  .| .|  |. |  .|.|.|.||| .|
FLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase HRR25.AA CK1 9-269 37 4.8e-134 451.61 In-house 1-339 (339) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-339/339
Sequence Identity: 37% (127 aa)

FRIGRKIGSGSFG-DIYHG-----TNLISG-----EEVAIKLESIRSR--HPQLDYESRVYRYLSGG-------------------VGIPFIRWFGREGE
.....|||.|.|| .||..     ... ..     ||.|.|.|.. |.  |||| .|...|..| ||                   ...| ..|.. |..
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

--YNAMVIDLLGPSLEDLFN---YCHRRFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGV------GRRGS--------TVHVIDFGLSK-KY
  || ||..||||.||||..    | |.|| ||..|.|.||  ...|.| . |||||||||||.||.      |..          .|..||||... ||
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKH-HHEWNNEHRQVYMIDFGMARRKY

RDF-----------NTHRHIPYRE---NKSLTG-TARYASVNTHLGIEQSRRDDLESLGYVLIYFCKGS--LPWQGLKATTK-------KQKYDRIMEKK
||            .|..|.|.||   .|...| ||||.|.|.|||.||.|||||.|..|.||.. ||.  ||||..|. .|       |.||. |.|||
RDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKK

LNVSVETLCSG-----LPLEFQEYMAYCKNLKFDEKPDYLFL
...... || .     .| || ..| |...||....||| ..
MSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase HRR25.AA Pkinase 9-273 22 9.7e-58 202.93 Pfam 1-293 (293) Show / Hide 
Range on Protein: 9-273
Range on HMM: 1-293/293
Sequence Identity: 22% (68 aa)

FRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDY------ESRVYRYLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYC------
..|||||||||||  |....  .|..||.|  . |..... |.      | .. . |.    . ...|| .....  || ....  |. ..  .      
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLY-VMDLFDYISTW

-HRRF--SFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMG-VGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHL-GIEQS
 |..|  | ..... ..|... ..|.| ...||||.||.|.|.   |  ...|...||||.|...      . ... .....|| .|..   .. | . .
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYG

RRDDLESLGYVLIYFCKGSLPWQGL----KATTKKQKYDRIMEKKLNVSVETLCSGL----------------PLEFQEYMAYCKNLKFDEKPD--YLFL
.. |  |.| .|.... | .|..|     .  ...|...|||...|  . ...||.                 . |... . .| ...  . |    .. 
PKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ

ARLF
   |
HPWF
Kinase HRR25.AA TTBKL 9-273 28 3.2e-50 167.76 In-house 1-288 (288) Show / Hide 
Range on Protein: 9-273
Range on HMM: 1-288/288
Sequence Identity: 28% (83 aa)

FRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRS-RHPQ--LDYESRVYRYLS--GGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLF-NYCHRR-FS
..| ..||.| || .||. .. . ...|.. |  ..  .    .  |  |   |.  |   .| . . |... || ||  |.||.| ||    .... ||
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

FKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGVG----RRGSTVHVIDFGLSKKYRDF----------NTHRHIPYRE---NKSLTGTARYASVNT
  |.  .. | .  ....|   |||||.|| |. .|.     .|  .|..||||....|...          |. .. . |.     .. || ||.|.| 
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM

HLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSG------LPLEFQEYMAYCKNLKFDEKPDYLFLARLF
|.. ||.| ||| |. |..|.. .| |||.... .      ..|...|.| . |.|...      .| || . | . ..|.. . |||  .  .|
HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDK------MEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase HRR25.AA Worm6 9-269 27 2.7e-48 166.76 In-house 1-279 (279) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-279/279
Sequence Identity: 27% (77 aa)

FRIGRKIGSGSFGDIYHGTNLISGE--EVAIKLES--IRSRHPQLDYESRVYRYL--SGGVGIPFIRWFGREGE--YNAMVIDLLGPSLEDLFNYC-HRR
. ...|||.|.||..|  ..   ..  ..|.|.|.    . ...|. |  |   .  ... . . |   |. ..  .| .|. |.|..|.||   .  |.
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK

FSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGV-----GRRGSTVHVIDFGLSK--KYRDFNTHRHIPYR-ENKSLTGTARYASVNTHLGIEQS
||. | . .|.|.  .|.  |   |||||.|| ||  |.      .  .|.  .|||...  ||.. .. .. | | ..    || |||... | |.||.
FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTP-RWTACGFRGTVRYAPLACHKGQEQC

RRDDLESLGYVLIYFCKGSLPWQGLKATTKKQ-KYDRIMEKKLNVSVETLCSGLPL-EFQEYMAYCKNLKFDEKPDYLFL
|.||.||  |... . .| |||...|..  ..  . ... ..  .  . .  . |  ||.. | |  .... ..||| |.
RKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase HRR25.AA TTBK 9-269 36 5.5e-48 165.74 In-house 1-257 (257) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-257/257
Sequence Identity: 36% (97 aa)

FRIGRKIGSGSFGDIYHGTNLISG-EEVAIKLESIRSRHPQLDYESRVYRYLSGGVGIPFIRWF---GREGEYNAMVIDLLGPSLEDLFNYCHR-RFSFK
 .. .||| | || || ....|   |.||||.|| .     |  |  | . |    | ...  |   ||. ..| || .|.| .| ||     |  ||  
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQ---GCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLS

TVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMG-VGRRGSTVHVIDFGLSKKYRDFNTHRHI-PYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGY
| . | .|.   |. ||   | |||||| || || .  .   .  .||||  .|   |..  . | ||     ||.||||.| |.  |  |.||| || |
TTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQY--TNACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFY

VLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSGLPLEFQEYMAYCKNLKFDEKPDYLFL
.|. | .| |||  .|        | . | |       |   .| ||. .|.  | |.. ..||| ..
MLVEFVQGQLPWRKIKDK------DQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase HRR25.AA VRK 80-222 33 6e-21 64.2 In-house 106-251 (284) Show / Hide 
Range on Protein: 80-222
Range on HMM: 106-251/284
Sequence Identity: 33% (50 aa)

MVIDLLGPSLEDLFN-YCHRRFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLT--GT
||.. .| .|. .    .  ||| |||  ||..|    .|.|     | |||  | | |     ..|  .|.||. .| .   ||  .| |..     ||
MVMPRFGRDLQKIYEDQNGHRFSMKTVLQLACRMLDVLEYLHENEYVHGDIKAANILLGFEKNPDQVYLVDYGLAYRYCPNGKHR--QYKEDPRRCHNGT

ARYASVNTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLKA--TTKK
  . |   |.|   ||| |||.||| ...   |.|||  ..    ..|
CEFTSMDAHKGCAPSRRSDLEILGYCMMMWLYGYLPWMDCLQQQDPEK
Kinase HRR25.AA S_TKc 9-288 18 8.4e-14 25.52 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-288
Range on HMM: 1-231/231
Sequence Identity: 18% (54 aa)

FRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRR--------F
..|.||||.|.||  | ...  .|..||||  .      ..  | .. .       . .. .|    ..  || .... .| ||| | ..|        |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

SFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSR-RDDLESL
.  ..  .. |..| ..|.| . .||||.||.| |.       .. ..||||....              ... ||  | .         .. . |  |.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSGLPLEFQEYMAYCKNLKFDEKPDYLFLARLFK-D----LSIKLEYH------NDHLF
| .|. .. |  |..     . .. ...|.                                 ..   |. .... |    ...    .      ..  |
GCILYEMLCGYPPFP-----QMQMMFKKIG--------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase HRR25.AA TyrKc 9-273 18 1e-06 -114.18 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-273
Range on HMM: 1-280/280
Sequence Identity: 18% (59 aa)

FRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYL----------SGGVGIPFIRWFGREGE---YNAMVIDLLGP--SLEDLF
 . |.|.|.| || .|.||     ..||.|     . .  .  | |. . |           | .  .. .             |..  . |  .| |  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN------FMYIEPLMIVMEYMPHGDLKDYL

NYCHRRFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYR--DFNTHRHIPYRENK--SLT--GTARYASVNTHLG
 ....... |. .  ..|  |  .|.| . .||||.   | | | ..   || . |||||..    | .  ..  ||  .  .       |  .      
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA------

IEQSRRDDLESL-GY------------VLIY--FCKGSLPWQG-------LKATTKKQKYDRIMEKKLNVSVETL----CSGLPLEFQEYMAYCKNLKFD
        .|..  .            |...  |  |  |. |        .   .. |  . |..  |.  . .    |   | |  . |  | . . .
--------PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSFVCC---PDEMYQIMKQCWHEDPE

EKPDYLFLARLF
. |    . ..|
DRPTFSEIHECF
Kinase HRR25.AA VRK 9-24 56 3.1e-05 13.19 In-house 1-16 (284) Show / Hide 
Range on Protein: 9-24
Range on HMM: 1-16/284
Sequence Identity: 56% (9 aa)

FRIGRKIGSGSFGDIY
.|.|..||.| || ||
WRLGKPIGQGGFGCIY
Kinase HRR25.AA Pkinase_Tyr 9-38 35 0.00011 16.49 Pfam 1-34 (270) Show / Hide 
Range on Protein: 9-38
Range on HMM: 1-34/270
Sequence Identity: 35% (12 aa)

FRIGRKIGSGSFGDIYHGTNL----ISGEEVAIK
 ..|.|.|.|.||..|.||        . .||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVK
Kinase HRR25.AA Pkinase_Tyr 117-129 38 5.598291 0.55 Pfam 125-137 (270) Show / Hide 
Range on Protein: 117-129
Range on HMM: 125-137/270
Sequence Identity: 38% (5 aa)

QYIHGRSFIHRDI
.| . . .||||.
EYLESKNCIHRDL