Gene RCK2 (Bakers Yeast)

RCK2

Species: Bakers Yeast
Alias: RCK2
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: CAMK
Family: CAMK1

Sequence

Name Sequence Type Origin Length Description Download
RCK2.AA Protein Refseq_NP 610 Serine/threonine protein kinase; Rck2p [Saccharomyces cerevisiae] Fasta, JSON
RCK2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 316 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of RCK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RCK2.AA CAMK1 163-478 36 1.1e-175 515.24 In-house 1-276 (276) Show / Hide 
Range on Protein: 163-478
Range on HMM: 1-276/276
Sequence Identity: 36% (118 aa)

YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSR---DQVLKEVALHKTVS-AGCSQIVAFIDFQE
|.....||.||||.|....  ...     | |.|..|||.|.|                |...|....   .....|.. .|.||   . .|..|....|
YEFGKEIGRGAFSEVYLCTHKETQ-----T-NGKQYAIKCIDK----------------KKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYE

TDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGI
.|...|...||.||||.|  ||  ....|.  ||..||.. ||..|||.|.||||.||||||......   ||. .                        
SDNHFYLVMELVTGGELFDRIVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKR-S------------------------

GIVKLADFGLSKQIFSK--NTKTPCGTVGYTAPEVVKD---EHYSMKVDMWGIGCVLYTMLCGFPPFYDEK-IDTLTEKISRGEYTFLKPWWDEISAG-A
    .|||||||.. ..  . ||.||| || ||||...   ..|....|||.||...|..|||.||||||  ...|.|||...||.| .||||.|| . |
----IADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEA

KNAVAKLLELEPSKRYDIDQFLDDPWL
|... ..||..|.|||...|.|..||.
KDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase RCK2.AA CAMK 168-478 23 9.3e-110 354.96 In-house 1-425 (425) Show / Hide 
Range on Protein: 168-478
Range on HMM: 1-425/425
Sequence Identity: 23% (106 aa)

KIGEGAFSKVFRAIPAKNSSNEF----LTKNYKAVAIKVIKKADLSSIN---------GDHRKKDKGKDSTKTSSRDQVLKEVALHKTVSAG-----CSQ
..|.|.|.||...|  ..  .|     .|.  . ||||.|.|  |.. .          |..|...... .. ..|..|..|....|.....        
TLGRGSFGKVKLCIHKNTTGKERVHHIYTN-GQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPN

IVAFIDFQE------------TDSY--------YYIIQ---ELLTGG----EIFGEIVRLTY---------------FSEDLSRHVIKQLALAVKHMHSL
|. .... |            | |.        .|..    |. .||    ..|  ||. ..               |.|.  |....|.. ||...||.
IIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

GVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKN-------------------------TKTPCG
..||||.||||.|.   .  ..  .  . .|       | || .    .  . .|..|||.........                          ||.||
NIVHRDLKPENILLDDNNDDSDP-V--E-HD-------E-IF-D----WNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCG

TVGYTA-PEVVKD--------------EHYSMKVDMWGIGCVLYTMLCGFPPFYDE-------------KIDTLTEKISRGEYTFLKPW-----------
| .| | |||..               . |. |.||| .|..||.||||.||||..              .  | ||| .|.|.|  |.           
TPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPE

-WDEISAG--------AKNAVAKLLELEPSKRYDIDQFLDDPWL
 ||.||          .|. . |.|. .|.||. |.| |..||.
WWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase RCK2.AA S_TKc 163-478 25 1.5e-83 284.81 SMART 1-231 (231) Show / Hide 
Range on Protein: 163-478
Range on HMM: 1-231/231
Sequence Identity: 25% (86 aa)

YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQETDSY
|....|||.|||.||....  |           . ||||.||                          .....|....|    ..  || ..|. .. ..
YEILRKIGKGAFGKVYKCRHKK---------TGRIVAIKIIK--------------------------EHIRREIQILKK---HHPNIVKLYDVFQD-DH

YYIIQELLTG--GEIFGEIVRLTY------FSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVG
.|.. |.. |  |. |  |..  .      |.|   |....|...|....||.|..|||.||||.|.                                 
LYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------------------------------

GGGIGIVKLADFGLSKQIFSKNTKTPCGTVGYTAPEVVKDEHYSM-KVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEYTFLKPWWDEISAGAKN
      .|..||||..|.     .| |||  | ||||.   .|.  |.|.| .||.|| |||| |||.   .... .||               |  ||.
-----HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKD

AVAKLLELEPSKRYDIDQFLD-------DPWL
 . |.|. .|.||. . . |        .||.
FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RCK2.AA AGC 163-478 18 4e-78 200.74 In-house 1-395 (395) Show / Hide 
Range on Protein: 163-478
Range on HMM: 1-395/395
Sequence Identity: 18% (86 aa)

YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNY-KAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSRDQVLKE--VALH----------------KTV
....  ||.|.|.||. .   .. .     |   |  |.||.||..                         |.|.     |                . .
FEFLKVIGKGSFGKVYLVRKKDGCH----KKDTGKYYAMKVLKKKH-----------------------KIVIKKKNMVEHTMTEHWKQDQGYVWEERNI

SAGCSQ------------IVA-FIDFQETDSY--YYIIQELLT---------GG-EIFGEIV---RLTYFSEDLSRHVIKQ-------LALAVKHMHS-L
 . |..            ||       .....   |.. |..          || | |  .    .  .|.|. .|. . .       ..||. ..|| .
LEKCNHTHNHPIKSHHPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHM

GVVHRD-IKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKN------------------------------
|..||| .||||.|.                                     | .||.||||.|.. ...                              
GIIHRDYLKPENILLDED----------------------------------GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCN

----------------------TKTPCG--TVGYTAPEVVKDEHYSMKVDMWG--IGCVLYTMLCGFPPFYDE----------KIDTLTEKISRGEYTFL
                      |.| ||  |  | |||..    |.  .| |.   ||..| ||.| ||||..            . . .||  |.|.. 
PNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFIN

KPWW------------DEISAGAKNAVAKLLELEPSKRYD----------IDQFLDDPWL
..              ...|  ||. . |||. .|.||            ...  . || 
WKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase RCK2.AA Pkinase 163-478 25 5.2e-75 260.3 Pfam 1-293 (293) Show / Hide 
Range on Protein: 163-478
Range on HMM: 1-293/293
Sequence Identity: 25% (91 aa)

YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDH---RKKDKGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQET
|... |||.|.|..|....  ...           ||.|.||| . .|    .   .                   |....| ..  .  || ..|. |.
YHIGRKIGSGSFGCVYKCHHKGTGK---------IVAVKIIKKRHEKSWKDQTHRRL------------------SEIQIMKRLN--HPNIVRLYDWFED

DSYYYIIQELLTGG----EIFGEIV--RLTYF--SEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTP
....|...|.. ||    . |  |   | . |  ||.  .....|.. .....|| |..|||.||||.|.     . .                      
KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA----------------------

GVGGGGIGIVKLADFGLSK---QIFSKNTKTPCGTVGYTAPEVVK-DEHYSMKVDMWGIGCVLYTMLCGFPPFYDE------KIDTLTEKISRGEYTFLK
        .||..||||.|      .  ..|.||| .| ||||.. ...|. |||||..||.|| |||| |||...        . . ..| .... |  
--------CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDW

PWWDEIS-----------------AGAKNAVAKLLELEPSKRYDIDQFLDDPWL
|||..||                   .|  . ..|.. |.||. ..| | .||.
PWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase RCK2.AA CAMKL 163-478 24 2.5e-66 210.61 In-house 1-297 (297) Show / Hide 
Range on Protein: 163-478
Range on HMM: 1-297/297
Sequence Identity: 24% (86 aa)

YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIK--KADLSSINGDH---RKKDKGKDSTKTSSRDQ-VLKEVALHKTVSAG-CSQIVAFID
|...  .|.|.|.||  |.  ..          . ||||.|.  |. .  .. ..   .|.          ..|. . .|....| .. |    |. . .
YRIGKTLGKGSFGKVKLATHIRTT--------GEKVAIKIIDKKKIWNDPWMKKNKCGQKH----------ESDMRIRREIQIMKMLNIGKHPNIIKLYE

FQETDSY------YYIIQELLTGGE--IFGEIVRLTY----FSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTK
  ||...      .|.. |.  |||   |  ||.  .    ..|.  |.  .|.  ||...||.|.|||||||||.|.                      
VIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN----------------

ADEGIFTPGVGGGGIGIVKLADFGLSKQIF------SKNTKTPCGTVGYTAPEVVKD--EHYS-MKVDMWGIGCVLYTMLCGFPPFYDEKI------DTL
                 .|..|||.| ..        .  || ||.  | |||....  ..|   |||.| .| .||.|.||  || |. .      .. 
----------------NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-

TEKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWL
...    .  .  | | ..|  ...   |.|.  |.||. |.| . .||.
YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase RCK2.AA Ciliate-E2 163-478 20 2.3e-61 209.38 In-house 1-365 (365) Show / Hide 
Range on Protein: 163-478
Range on HMM: 1-365/365
Sequence Identity: 20% (89 aa)

YKLINKIGEGAFSKVFRAIPAKNSSNE---FLTKNY------------KAVAIKVIKKADLSSI-NGDH--RKKDKGKDSTKTSSRDQVLKEVALHKTVS
||.|.|||.|.|..|...   |.  ..   . . ..            | .|.|..|| .. .| . .|  |...  .                      
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-F----------------------

AGCSQ---------------IVAFIDFQE--TDSYYYIIQELLTGGEIFGEIV------------RLTYFSEDLSRHVIKQLAL---------------A
                    |. .... .  .|...|.. |.. ||. |  |                ||.|   ....||..                |
--Y-KKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILA

VKHMHSLG-VVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKTP-------------------
....|| . ..||||||||.||                                       .|..||||||..  .| ..                    
LEYLHSKNNIIHRDIKPENILF---------------------------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPG

--------------CGTVGYTAPEVVKDEH---------YSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEYTFLKP------------W--
              ||| || |||... .          |. |.|.| .|..|| ||.| |||         ..|  ... | .|            |  
YMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKS

WDEISAGAKNAVAK----LLELEPSKRYD-IDQFLDDPWL
|...|  .|.   |    .|. .|.||.. ..| |. ||.
WKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase RCK2.AA Ciliate-E2-Unclassified 163-478 19 1.3e-56 194.34 In-house 1-352 (352) Show / Hide 
Range on Protein: 163-478
Range on HMM: 1-352/352
Sequence Identity: 19% (82 aa)

YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKAD------------LSSINGDHRKKDKGKDSTKTSSRDQVLKEVALHKTVSAGCSQ-
||.| .||.|.|.||....  |.   ..  . |. ..... .|              . .....| .|                              . 
YKIIKQIGQGGFGKVYKCQHKKQK--QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRK----------------------------Y-NK

-------------IVAFIDFQETDSYYYIIQELLTGGEIFGEIVRLTY-----------------FSEDLSR-----HVIKQLALAVKHMHSLG-VVHRD
             || ...  ... . ||. |.. ||. .  |                      |.|  ..     . ..|. .. ...|. . ..|||
IMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRD

IKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSK-----------------QIFSKNTKTPCGTVGYT----APEVV
|||||.||                                     . .|..|||.||                 .. .....| ||| .|     |||| 
IKPENILFDNNGK-------------------------------NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVL

KDEHYS----MKVDMWGIGCVLYTMLCGFPPFYDEKIDT----------------LTEKISRGEYTFLKPWW----DEISAGAKNAVA----KLLELEPS
. ..|.     |.|.|. |..|| || | .||||.. .                 | ..|  ... | | .|    . .|  ||. .     |.|.  |.
QGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPN

KRYDIDQFLDDPWL
||....| |  ||.
KRITFEQILNHPWF
Kinase RCK2.AA RAD53 360-478 40 1.9e-46 136.05 In-house 165-305 (305) Show / Hide 
Range on Protein: 360-478
Range on HMM: 165-305/305
Sequence Identity: 40% (58 aa)

IVKLADFGLSKQIFSKNT---KTPCGTVGYTAPEVVK-------DEH--------YSMKVDMWGIGCVLYTMLCGFPPFYDE-----KIDTLTEKISR-G
..|..||||||  |. ..   || |||  | ||||.        .|.        |. |||.| .||.||..|||.||| |.     . ..| |.| . |
LIKITDFGLSK--FVGEGSFMKTMCGTPQYVAPEVITSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQG

EYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWL
 | | .| ||.||  ||. . ..| ..| ||| ||. |  ||.
KYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEALNHPWM
Kinase RCK2.AA CAMK-Unique 361-478 28 4e-41 133.39 In-house 212-363 (363) Show / Hide 
Range on Protein: 361-478
Range on HMM: 212-363/363
Sequence Identity: 28% (44 aa)

VKLADFGLSKQIFSKNTK----TPCGTVGYTAP--------------EVVKDEHYSMKV----DMWGIGCVLYTMLCGFPPFYDEKID--------TLTE
.||.||||.... ..       | |||  | ||              ||..   |. ..    | | .| ..|.|||| |||. | .|         . |
IKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDKEIFE

KISRGEY-TFLKPWWDE---ISAGAKNAVAKLLELEPSKRYDIDQFLDDPWL
.|. |.| .| ...|.    || .||..| ......|..|  . . |. .|.
CICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase RCK2.AA MAPKAPK 360-478 33 2.4e-38 116.02 In-house 144-292 (292) Show / Hide 
Range on Protein: 360-478
Range on HMM: 144-292/292
Sequence Identity: 33% (50 aa)

IVKLADFGLSKQ-------IFS---KNTKTPCGTVGYTAPEVVKDEH----YSMKVDMWGIGCVLYTMLCGFPPFYDEKI------D----------TLT
.||| |||. |.         .    . .|||.|  | |||||  .     |  . ||| .| ..| ||||.|||| ..       |           . 
PVKLCDFGFAKEIHLNHDCTTPITTPELMTPCYTPYYMAPEVVGAFKEAHTYDKSCDMWSLGVIMYIMLCGYPPFYSNCGDEDCSWDRGEACRDCQNMMF

EKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWL
..|  |.|.|  . |..||. ||. . |||  .|..|. | |... ||.
HRIQEGQYEFPDEEWSHISEEAKDLIRKLLRRDPTQRLTIEQVMNHPWI
Kinase RCK2.AA RSK 361-478 30 2.1e-36 127.24 In-house 146-278 (278) Show / Hide 
Range on Protein: 361-478
Range on HMM: 146-278/278
Sequence Identity: 30% (40 aa)

VKLADFGLSKQ-IFS--KNTKTPCGTVGYTAPEVVK----DEHYSMKVDMWGIGCVLYTMLCGFPPFYD---EKIDTLTEKISRGEYTFLKPWWDEISAG
.|| |||..||   .  . |.|.|.|. | |||..|    .. ..  .| |  |...|.|| |.|||.    .  . . ..| .|....  | |...|. 
IKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQE

AKNAVAKLLELEPSKRYD-----IDQFLDDPWL
||. . |.|. .|.||.      ... ...||.
AKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase RCK2.AA CAMK-Unique 163-321 21 2.7e-31 100.43 In-house 1-190 (363) Show / Hide 
Range on Protein: 163-321
Range on HMM: 1-190/363
Sequence Identity: 21% (44 aa)

YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDH-RKKDKGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDF----Q
||... ||.|.|..|....   .....      |  |.|..||.. ... ..  |  |  .  |      .  .|... |.|.  .  |. . |.     
YKMHRIIGHGNFGHVYECM---DRETG------KKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPN--IIKLYDWNNPIF

ETDS---------------YYYIIQELLTGGEIFGEIVR--------------------LTYFSE--DLSRHVIKQLALAVKHMHSLGVVHRDIKPENLL
...                |.||..|...||. | .|..                     ..|||   ... .. .|. ||..|||...||||.|.||..
CDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIM

F
.
V
Kinase RCK2.AA MAPKAPK 222-322 33 3.9e-29 86.99 In-house 33-137 (292) Show / Hide 
Range on Protein: 222-322
Range on HMM: 33-137/292
Sequence Identity: 33% (36 aa)

KDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQET----DSYYYIIQELLTGGEIFGEIVR--LTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIK
.|. .. ||  ...|| ||.... |.  ||  ||. |     |.  |.. |.. |||.|  | .    .|.|   . ..|. ..||...||..  |||.|
EDQ-PGHSRQKARREVELHWHCQ-GHPNIVQIIDWFENMYQFDKCFYLVMECMEGGELFQHIQQRGHKHFTEREASQIMKDICSAVDFLHSMNIAHRDLK

PENLLFE
|||.|..
PENILCT
Kinase RCK2.AA RAD53 163-322 32 5.2e-27 77.05 In-house 1-143 (305) Show / Hide 
Range on Protein: 163-322
Range on HMM: 1-143/305
Sequence Identity: 32% (53 aa)

YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQET-DS
| .. ..| |.|..| .|.          .|. . |||| |.|  .. | .          .. ....||| .||   | ..  |  |....|. .| . 
YYMSKELGSGNFGTVKLAY---------EKKTCQKVAIKIIDKKKFF-IRC----------MHTIKKMDQVMNEVEILKKLNHPC--IIRIYDIFDTPQK

YYYIIQELLTGGEIFGEIVRLTY----FSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFE
|||.. || |||| |  ||   .    |.|| ..   .|. .|||  |..| .|||.|||| |..
YYYMVLELMTGGELFNKIVSNKRCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCN
Kinase RCK2.AA RSK 258-331 35 4.6e-21 73.99 In-house 71-147 (278) Show / Hide 
Range on Protein: 258-331
Range on HMM: 71-147/278
Sequence Identity: 35% (28 aa)

ETDSYYYIIQELLTGGEIFGEIVRLTY---FSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFT-RSIK
.|... |.| |.. ||| |  . .  .   ||||  . .. ...|||.|.|..|..|||.|||| |.. .. . ..||
QTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIK
Kinase RCK2.AA TyrKc 163-473 14 2.8e-11 -40.23 SMART 1-280 (280) Show / Hide 
Range on Protein: 163-473
Range on HMM: 1-280/280
Sequence Identity: 14% (53 aa)

YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSRDQVLKEVALHKTV--SAGCSQIVAFIDFQETD
 .|. |.||||| .|....                ||.|..|.                        |   ..|  . . .  .  .  ||...    ..
ITLGKKLGEGAFGEVYKGTWK------------IQVAVKMLKEDA----------------------REDFMREARIMCKLGGHHPN--IVRLYGVCTQQ

-------SYYYIIQELLTGGEIFGEIVRLTY--FSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTP
         ..|. |.  .|    .  | .   .. .   .   | |    . || ...|||.   | |                               
GRNFMYIEPLMIVMEYMPHGD-LKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--------------------------

GVGGGGIGIVKLADFGLSKQIFSK-------NTKTP----CGT----VGYTAPEVVKDEHYSMKVDMWGIGCVLYTML-CGFPPFYD-----EKIDTLTE
        .|| .|||||. | ..        ....    .|     .  .|||. ..  .. | | |  | ... ..  | .| ..      . . . |
--------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIE

KISRGEYTFLKPW-----WDEISAGAKNAVAKLLE----LEPSKR---YDIDQFL
.. .|..    |            ..  .. .. .     .|..|    .| ...
YVKQGYRMPQPPNDYPMSF----VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase RCK2.AA Pkinase_Tyr 163-204 28 0.005268 10.8 Pfam 1-37 (270) Show / Hide 
Range on Protein: 163-204
Range on HMM: 1-37/270
Sequence Identity: 28% (12 aa)

YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIK
 ... |.||||| .|.... .|        ..   ||.|..|
ITFGKKLGEGAFGEVYKGT-WKG----DPDNTKIPVAVKMLK
Kinase RCK2.AA Pkinase_Tyr 359-411 25 0.015849 9.18 Pfam 148-205 (270) Show / Hide 
Range on Protein: 359-411
Range on HMM: 148-205/270
Sequence Identity: 25% (15 aa)

GIVKLADFGLSKQI------FSKNTKTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLY
..|| .||||.. |      . | ....   .  .|||. ..  .. | | |  | ...
NVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVWSFGVLMW