Gene RIM15 (Bakers Yeast)

RIM15

Species: Bakers Yeast
Alias: RIM15
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: AGC
Family: NDR
Subfamily: NDR-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
RIM15.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 269 Kinase domain by global Sugen HMM Fasta, JSON
RIM15.AA Protein Refseq_NP 1770 RIM15 is glucose-repressed; RIM15 is required for IME2 expression; Rim15p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of RIM15.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RIM15.AA AGC 794-1254 22 4.4e-159 414.93 In-house 1-395 (395) Show / Hide 
Range on Protein: 794-1254
Range on HMM: 1-395/395
Sequence Identity: 22% (128 aa)

YDILKPISKGAYGSVYLARKK------LTGDYFAIKVLRKSD-MIAKN--QVTNVKSE------------RAIMMVQSDK---------PYVAR-LFASF
...||.|.||..| |||.|||       ||.|.|.|||.|.. .. |.  .| ....|            | |..  . .         |.. . |. ||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QNKDN--LFLVMEYLP--------GGDLATLIKMMG-----YLPDQWAKQYLTE-------IVVGVNDMHQ-NGIIHHD-LKPENLLIDNAGHVKLTDFG
|.||.  |..||||.|        ||.. ... ..|     ... ..|. |. |       || ..  .|. .|||| | |||||.|.|. ||.||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSRAGLIRRHKFVPHKSSLSISSTLPIDNPANNFTMNNNNSNHSQLSTPDSFTSDHKQYNRSKKSSLGQQYEHSEYSSTSNSHSMTPTPSTNTVVYPSYY
|.  |  ...| ..   |.               ...  |... | ..  ...    . |                                        
LCKEGMNDGEKGQQ-SQSN-------------MKFHW-HNKKY-Q-KS--NMD----T-N----------------------------------------

RGKDRSHGSSNIDLPASLRRSESQLSFSLLDISRSSTPPLANPTNSNANNIMRRKSLTENKSFSNDLLSSDAIAATNTNINSNNNISLSPAPSDLALFYP
                                                                                            . . .   
--------------------------------------------------------------------------------------------K-CNPNNW

DDSK-------------QNKKFFG--TPDYLAPETIEGKGEDNKQCDWWS--VGCIFFELLLGYPPFHAETPD----------AVFKKILSGV--IQWPE
.. .             ... | |  ||.|.||| .      .|.|||||  .||...|.| |||||....|.           .|.||..|   |.|..
QRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKV

FKN-----EEEEREFLTPEAKDLIEKLLVVDPAKRLGAK-------GIQEIKDHPYF
  .     ...|.....|||||||.|||..||.||||..       |..|||.||.|
KFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase RIM15.AA MAST 794-1254 30 5.4e-142 436.93 In-house 1-337 (337) Show / Hide 
Range on Protein: 794-1254
Range on HMM: 1-337/337
Sequence Identity: 30% (142 aa)

YDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQN--KDNLFLVMEYLPGGDLATLIKMMG-YL
....|.||||||| |||...| |.| ||.||....|.| |||| .|..|| |  .. . |.|  .| |||   |. |..||||. ||| |.|..|.|  .
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNI-LTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCM

PDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLSRAGLIRRHKFVPH-KSSLSISSTLPIDNPANNFTMNNNNSNHSQLSTPDS
|   ||.|. |.| ..   |  ||.| ||||.|.|||  ||.||||||||  |.. . . ..  . .  |.                             
PEWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEGYFNTNIFGK---------------------------

FTSDHKQYNRSKKSSLGQQYEHSEYSSTSNSHSMTPTPSTNTVVYPSYYRGKDRSHGSSNIDLPASLRRSESQLSFSLLDISRSSTPPLANPTNSNANNI
                                                                                                    
----------------------------------------------------------------------------------------------------

MRRKSLTENKSFSNDLLSSDAIAAT-NTNINSNNNISLSPAPSDLALFYPDDSKQNKKFFGTPDYLAPETIEGKGEDNKQCDWWSVGCIFFELLLGYPPF
   .. .| ..  |  .....   . |||.|. .   ..| .       |   .|||.  |||||.||| | |.|  .|  ||||.| | .|.| |.|||
---NHFNEYHIQKNYQQFQQDFGINGNTNKNQIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPF

HAETPDA-VFKKILS--GVIQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLGAKGIQEIKDHPYF
 ..||   .| .|..    | |||    . . . ..|||.|||.||| ..| |||||.| .||| ||.|
NGDTPEEMIFQNIINHDREIEWPEEGDPN-DDDCMSPEAQDLIKKLLQPNPKKRLGANGADEIKQHPFF
Kinase RIM15.AA MAST 794-1254 31 3.2e-136 441.82 In-house 1-334 (334) Show / Hide 
Range on Protein: 794-1254
Range on HMM: 1-334/334
Sequence Identity: 31% (147 aa)

YDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQ
... ||||||||| |||...| |.| ||.||..||||| ||.| .|..|| |   ... |.|  .| ||| |..|..||||. |||.|.|..|.||..  
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNI-LAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEW

WAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLSRAGLIRRHKFVPH-KSSLSISSTLPIDNPANNFTMNNNNSNHSQLSTPDSFTS
 ||.|. |.| ..   |. ||.| ||||.|.|||. ||.||||||||  |.... . ..  . .  |                                 
MAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNI---------------------------------

DHKQYNRSKKSSLGQQYEHSEYSSTSNSHSMTPTPSTNTVVYPSYYRGKDRSHGSSNIDLPASLRRSESQLSFSLLDISRSSTPPLANPTNSNANNIMRR
                                                                                                .   
------------------------------------------------------------------------------------------------FNNS

KSLTENKSFSNDLLSSDAIAATNTNINSNNNISLSPAPSDLALFYPDDSKQNKKFFGTPDYLAPETIEGKGEDNKQCDWWSVGCIFFELLLGYPPFHAET
.. . ..   .  .  |    .|||.|. .   ..| .       |   .|||.  |||||.||| | |.|  .|  ||||.| |..|.| |.|||  .|
TDPMNKNQQDYSQFPGDFGINGNTNKNQIQQQQEQPQCQQQN-MRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDT

PDAVFKKILSGV---IQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLGAK-GIQEIKDHPYF
|. .| .||.     | |||    . . | ..|||.||||||| .|| |||||. | .|.| ||.|
PEEIFQNILNRNCNEIEWPEGGDIN-DDEAMSPEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
Kinase RIM15.AA NDR 794-950 49 3.4e-108 334.9 In-house 1-161 (350) Show / Hide 
Range on Protein: 794-950
Range on HMM: 1-161/350
Sequence Identity: 49% (80 aa)

YDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDK-PYVARLFASFQNKDNLFLVMEYLPGGDLAT---LIKMMGY
..|.|.|.|||.| |.|.||| ||...|.|..|||.|. ||||..|..|| ||.....| |.| .|. |||.|..|.|||||.||||. |   |...|..
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLSRAGLIRRHKF
....||..| .|.|. ....|..|.||.|.||.|.|||. ||.|||||||.. |.||||..
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWK
Kinase RIM15.AA S_TKc 794-1254 22 8.6e-100 338.75 SMART 1-231 (231) Show / Hide 
Range on Protein: 794-1254
Range on HMM: 1-231/231
Sequence Identity: 22% (106 aa)

YDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPG--GDLATLIKMMGY--
|.||..| |||.|.||..|.| || ..|||...           ....|..|..   . |.. .|. .||. |.|..||||..|  ||| ..|| .|.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLSRAGLIRRHKFVPHKSSLSISSTLPIDNPANNFTMNNNNSNHSQLS
    .|  .|. |. .|. ... .|..|||| ||||||.|.|.  |.|..||||.|                                            
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------------------------

TPDSFTSDHKQYNRSKKSSLGQQYEHSEYSSTSNSHSMTPTPSTNTVVYPSYYRGKDRSHGSSNIDLPASLRRSESQLSFSLLDISRSSTPPLANPTNSN
                                                                                                    
----------------------------------------------------------------------------------------------------

ANNIMRRKSLTENKSFSNDLLSSDAIAATNTNINSNNNISLSPAPSDLALFYPDDSKQNKKFFGTPDYLAPETIEGKGEDNK-QCDWWSVGCIFFELLLG
                                                           . | |||.|.||| .      .|  |||||.|||..|.| |
-----------------------------------------------------------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCG

YPPFHAETPDAVFKKILSGVIQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLGAKGIQE----IKDHPYF
||||.  .....||||.                   .|||||.|.|.|..||.||..|  . .    || ||.|
YPPFP--QMQMMFKKIG-------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RIM15.AA AktR 794-1254 22 1.1e-88 300.96 In-house 1-268 (268) Show / Hide 
Range on Protein: 794-1254
Range on HMM: 1-268/268
Sequence Identity: 22% (106 aa)

YDILKPISKGAYGSVYLARKK-LTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPD
....|.. |||.| |||..||  .....|.|...|...| .||   .  || ||  ... |   .|. .||.|..||..||| |||.| . .|  . .  
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

QWAKQYLTEIVVGVNDMHQN-GIIHHDLKPENLLIDNAGHVKLTDFGLSRAGLIRRHKFVPHKSSLSISSTLPIDNPANNFTMNNNNSNHSQLSTPDSFT
. |. |  .|. ..   ||.  ||  ||||||.|.|  ||||.||||||.                                                  
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK--------------------------------------------------

SDHKQYNRSKKSSLGQQYEHSEYSSTSNSHSMTPTPSTNTVVYPSYYRGKDRSHGSSNIDLPASLRRSESQLSFSLLDISRSSTPPLANPTNSNANNIMR
                                                                                                    
----------------------------------------------------------------------------------------------------

RKSLTENKSFSNDLLSSDAIAATNTNINSNNNISLSPAPSDLALFYPDDSKQNKKFFGTPDYLAPETIEG-KGEDNKQCDWWSVGCIFFELLLGYPPFHA
                                           .|  ...  ...|.||| |.|||.|   ||  ||..|||..|.  .|.. |.||| .
------------------------------------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKG-HNKSVDWWAFGIFIYEMVTGCPPFYH

ETPDAVFKKILSGV-IQWPEFKNEEEEREFLTPEAKDLIE-KLLVVDPAKRLG--AKGIQEIKDHPYF
.     |.||..   .. |. ..       .....||||. |||  .| ||||  ..|..|||.|| |
KNQNQMFQKIKIKQQNKFPYPSY-------FSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase RIM15.AA RSK 797-1254 22 3.2e-85 289.44 In-house 1-278 (278) Show / Hide 
Range on Protein: 797-1254
Range on HMM: 1-278/278
Sequence Identity: 22% (106 aa)

LKPISKGAYGSVYLARKK---LTGDYFAIKVLRKSDMIAKNQ-VTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGY---
||   .|.||.|.| ||.    || ..| |||.|. .....  .  .. || |..     | . .|. .|| .. |.|.|||..||.| | ..  ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDN---AGHVKLTDFGLSRAGLIRRHKFVPHKSSLSISSTLPIDNPANNFTMNNNNSNHSQLST
.    |..|. |||. |  .|| |||| |||||| | |.    ||.||||||... .                                           
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-------------------------------------------

PDSFTSDHKQYNRSKKSSLGQQYEHSEYSSTSNSHSMTPTPSTNTVVYPSYYRGKDRSHGSSNIDLPASLRRSESQLSFSLLDISRSSTPPLANPTNSNA
                                                                                                    
----------------------------------------------------------------------------------------------------

NNIMRRKSLTENKSFSNDLLSSDAIAATNTNINSNNNISLSPAPSDLALFYPDDSKQNKKFFGTPDYLAPETIE---GKGEDNKQCDWWSVGCIFFELLL
                                                   .|.... ..| .| .|.||| .    ..|  .|.||||| |.. .|.| 
--------------------------------------------------RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLT

GYPPFHA---ETPDAVFKKILSGVIQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLG--AKGIQEIKDHPYF
|.|||..   .... ..|.|..|     .|  . .. ..|..|||||| |.| .||.||||   ....|||.||.|
GCPPFQGPNDNNRKEIMKRIQKG-----KFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase RIM15.AA Ciliate-E2-Unclassified 794-1254 17 4.4e-78 265.71 In-house 1-352 (352) Show / Hide 
Range on Protein: 794-1254
Range on HMM: 1-352/352
Sequence Identity: 17% (99 aa)

YDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNV---------KSER---------AIMM---VQSDKPYVARLFASFQNKDNLFLVM
| |.| | .|..|.||....| .. |.|.| . |. .....|. |.           ..          ||    .... |.. ..|  ||.|.|...||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYLPGGDLATLIKMM-----------------GYLPDQWAK-----QYLTEIVVGVNDMHQNG-IIHHDLKPENLLIDNAG---HVKLTDFGLSR-----
||..||||   || .                   ...| ||     .|. .|..| . .|... ||| |.||||.|.|| |   ..|..|||.|.     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

------AGLIRRHKFVPHKSSLSISSTLPIDNPANNFTMNNNNSNHSQLSTPDSFTSDHKQYNRSKKSSLGQQYEHSEYSSTSNSHSMTPTPSTNTVVYP
                                                                                                    
NNCDTNQ---------------------------------------------------------------------------------------------

SYYRGKDRSHGSSNIDLPASLRRSESQLSFSLLDISRSSTPPLANPTNSNANNIMRRKSLTENKSFSNDLLSSDAIAATNTNINSNNNISLSPAPSDLAL
                                                                                                    
----------------------------------------------------------------------------------------------------

FYPDDSKQNKKFF---------GTPDYL----APETIEGKGEDN---KQCDWWSVGCIFFELLLGYPPFHAETPDA----------------VFKKILSG
      .|.....         ||| |.    ||| ..|.. |.   ..||.||.|.|..|.| ||.|| ... .                 ....|. .
------QQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQK

VIQWPEFKN----EEEEREFLTPEAKDLIE----KLLVVDPAKRLGAKGIQEIKDHPYF
 || |.|..           . |||||.|.    |.|...| ||.   ....|. ||.|
NIQFPKFPWQQIPKH-----WSPEAKDFINDLLQKMLKKNPNKRI---TFEQILNHPWF
Kinase RIM15.AA NDR 1146-1254 45 1.8e-69 213.24 In-house 240-350 (350) Show / Hide 
Range on Protein: 1146-1254
Range on HMM: 240-350/350
Sequence Identity: 45% (51 aa)

KFFGTPDYLAPETIEGKGEDNKQCDWWSVGCIFFELLLGYPPFHAETPDAVFKKILSGVIQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLGA--K
...|||||.||| ...|...|..|||||.|||..|.| |||||...||. ...||..  ..|...... .....|.|||.|||..|. .|| .|||.  |
STVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGK

GIQEIKDHPYF
|..|||.||.|
GVDEIKSHPFF
Kinase RIM15.AA Akt 794-948 40 3.3e-52 165.16 In-house 1-156 (264) Show / Hide 
Range on Protein: 794-948
Range on HMM: 1-156/264
Sequence Identity: 40% (63 aa)

YDILKPISKGAYGSVYLARKKLTGDYF-AIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPD
 |.|| . ||..| |.|..|| |.... |.|||.|.  |.|||| ..| || |  .  . |..  |  |||..|.|..||.| .||.| ....  .. . 
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNI-LQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE

QWAKQYLTEIVVGVNDMHQNGIIHHD-LKPENLLIDNAGHVKLTDFGLSRAGLIRRH
. |. |  ||. .    |...||  | |||||.|.|. ||..||||||.. ..| .|
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDH
Kinase RIM15.AA PKA 794-938 36 1.4e-44 154.45 In-house 1-146 (263) Show / Hide 
Range on Protein: 794-938
Range on HMM: 1-146/263
Sequence Identity: 36% (54 aa)

YDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVAR-LFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPD
..|.. . .| .| |.|.|.| .|.|.|.|.|.|.. .  .||  |..|. |.. . . |.. . . ..||. ..|..|||| |||.. . .   | .. 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQ-NIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSN

QWAKQYLT-EIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFG
. || | . .||     .|.  ||. ||||||.|||. ||.|.||||
PHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFG
Kinase RIM15.AA Pkinase 794-941 37 9.8e-43 152.18 Pfam 1-160 (293) Show / Hide 
Range on Protein: 794-941
Range on HMM: 1-160/293
Sequence Identity: 37% (60 aa)

YDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVK-SERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGG----DLATLIK--M
| |...| .|..|.||....| ||. .|.|...|..   . ..|... || .||    . |.. ||. .|..||.. .||||..||    ||...|.  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

MGYL--PDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHV----KLTDFGLSR
 | .  ... .| |...|. |.. .|..|||| ||||||.|||| ||.    |..||||..
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAK
Kinase RIM15.AA Ciliate-E2 794-941 23 2e-41 139.94 In-house 1-204 (365) Show / Hide 
Range on Protein: 794-941
Range on HMM: 1-204/365
Sequence Identity: 23% (50 aa)

YDILKPISKGAYGSVYLARKKLTGD-----------------------YFAIKVLRKSDMIAKNQVTNVK----------SERAIMMVQSDKPYVARLFA
|...| | .|..||||........                        ..|.|...|.. ....|. ..            |. |.  | . |.. ... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILE-QLNHPNIIKMYE

SFQ--NKDNLFLVMEYLPGGDLATLIK-------------------MMGYLPDQWAK-------QYLTEIVVGVNDMHQNG-IIHHDLKPENLLIDNAGH
.||  ...|..|||||. ||||  .||                    ..|.  | ..        |...|..... .|... ||| |.||||.|.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKLTDFGLSR
.|..|||||.
IKIIDFGLSK
Kinase RIM15.AA Akt 1149-1254 43 9.1e-39 121.5 In-house 164-264 (264) Show / Hide 
Range on Protein: 1149-1254
Range on HMM: 164-264/264
Sequence Identity: 43% (47 aa)

GTPDYLAPETIEGKGEDNKQCDWWS-VGCIFFELLLGYPPFHAETPDAVFKKILSGVIQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLG--AKGI
||| ||||| ..|.| . |..|||. .||...|.. | |||...  .  ||||... .. |.       .... ||.||||..||  || ||||   ...
GTPEYLAPEILNGNGHT-KAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPD-------KDWISPECKDLISGLLNKDPKKRLGGGPNDA

QEIKDHPYF
||||.||.|
QEIKRHPWF
Kinase RIM15.AA Ciliate-E2 1149-1254 33 1.1e-36 123.45 In-house 249-365 (365) Show / Hide 
Range on Protein: 1149-1254
Range on HMM: 249-365/365
Sequence Identity: 33% (42 aa)

GTPDYLAPETIEGKGEDN--------KQCDWWSVGCIFFELLLGYPPFHAETPDAVFKKILSGVIQWPEFKNEEE---------EREFLTPEAKDLIEK-
||| |.||| ..||..||        ..||.||.|.|..|.| |.|||        ...|. . |. |.......         . . ...|.|||| | 
GTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKF

---LLVVDPAKRLGAKGIQEIKDHPYF
   .|..|| ||..  |...|..||.|
GKRMLQKDPEKRIT--GWEQILNHPWF
Kinase RIM15.AA PKA 1149-1254 41 6.4e-33 115.7 In-house 160-263 (263) Show / Hide 
Range on Protein: 1149-1254
Range on HMM: 160-263/263
Sequence Identity: 41% (47 aa)

GTPDYLAPETIEGK-GEDNKQCDWWSVGCIFFELLLGYPPFHAE--TPDAVFKKILSGVIQWPEFKNEEEEREFLTPEA---KDLIEKLLVVDPAKRLGA
|||.||||| | .| |  .|  |||. |.. .|.| ||||| ..  .| . ..||..| |..|.         .... |   ||||.|||.||. ||.| 
GTPEYLAPEIIQSKNG-HGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPR---------HFDSDANYFKDLIKKLLQVDLTKRYGN

K--GIQEIKDHPYF
.  |.. ||.|. |
MKNGVNDIKNHKWF
Kinase RIM15.AA Pkinase 1133-1254 27 1.2e-29 105.97 Pfam 158-293 (293) Show / Hide 
Range on Protein: 1133-1254
Range on HMM: 158-293/293
Sequence Identity: 27% (39 aa)

LALFY-PDDSKQNKKFFGTPDYLAPETIEGKGEDNKQCDWWSVGCIFFELLLGYPPFHAE------TPDAVFKKILSGVIQWPEFKNEEEEREFLT----
|| ..    .  .. | |||.|.||| | |  .. . .|.||.|||..|.|.|.|||  .      ........|... . .....  .. ..| .    
LAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRHWH

---------PEAKDLIEKLLVVDPAKRLGAKGIQEIKDHPYF
         .|.||.|...| .||.||..   ...|. ||.|
FHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF
Kinase RIM15.AA S_TK_X 1255-1321 19 1e-09 39.55 SMART 1-79 (79) Show / Hide 
Range on Protein: 1255-1321
Range on HMM: 1-79/79
Sequence Identity: 19% (16 aa)

KNVDWDHVY----DEEASFVPTID----NPEDTDYFDLRGAELQDFGDDIENDNANILFGKHGINT--------DVSELSAAN
...|||..|      |. |.|.|     .|.|| .||    | ..     . .   .|.. .. |         .  .... .
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM----LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase RIM15.AA TyrKc 794-1220 11 3.4e-09 -74.07 SMART 1-280 (280) Show / Hide 
Range on Protein: 794-1220
Range on HMM: 1-280/280
Sequence Identity: 11% (55 aa)

YDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQ-SDKPYVARLFASFQNK-------DNLFLVMEYLPGGDLATLIK
   .| .  ||.| ||... |      |.|.|...       .    .|  ||.    . | . ||..    .       . |..|||| |.|||   ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

MMGY-LPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLSRAGLIR-------RHKFV----PHK------------SSLSISS
  .  |. .   .. . |  | .  |....|| ||   | |... ..|| .||||||..            . .      |               .. .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

T-------------------LPIDNP----ANNFTMNNNNSNHSQLSTPDS----FTSDHKQYNRSKKSSLGQQYEHSEYSSTSNSHSMTPTPSTNTVVY
|                    |  ..     .|. . ..  .   .  |..                                                 
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------------------------

PSYYRGKDRSHGSSNIDLPASLRRSESQLSFSLLDISRSSTPPLANPTNSNANNIMRRKSLTENKSFSNDLLSSDAIAATNTNINSNNNISLSPAPSDLA
                                                                                                    
----------------------------------------------------------------------------------------------------

LFYPDDSKQNKKFFGTPDYLAPETIEGKGEDNKQCDWWSVGCIFFELLLGYPPFHAETPDAVFKKILSGVIQW-----PEFKNEEEEREFL
                                                     |  . ||.... | .   .      | |..    .|..
-----------------------------------------------------F-VCCPDEMYQ-IMKQCWHEDPEDRPTFSEI---HECF
Kinase RIM15.AA Pkinase_Tyr 923-942 45 0.012241 9.56 Pfam 141-160 (270) Show / Hide 
Range on Protein: 923-942
Range on HMM: 141-160/270
Sequence Identity: 45% (9 aa)

NLLIDNAGHVKLTDFGLSRA
| |... ..|| .||||.|.
NCLVTENNVVKICDFGLARD
Kinase RIM15.AA Pkinase_Tyr 794-880 28 0.141501 5.96 Pfam 1-94 (270) Show / Hide 
Range on Protein: 794-880
Range on HMM: 1-94/270
Sequence Identity: 28% (27 aa)

YDILKPISKGAYGSVYLARKK----LTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQ-NKDN--LFLVMEYLPGGDL
  ..| . .||.|.||... |     |.   |.|.|. . |   |      .| .||.   . | . || .     ..   ...|||| |.|||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL
REC RIM15.AA REC 1635-1746 15 4.2e-12 47.47 SMART 1-150 (150) Show / Hide 
Range on Protein: 1635-1746
Range on HMM: 1-150/150
Sequence Identity: 15% (25 aa)

MDVLVCEPI----PIHRYRVT------KDLENLGCT--------VVSVGAGD-------ELVSRATSG------------VSFDLIMTALKLP-------
| .|...      |. |  ..      . || .|..        |...  |.       | . .. ..              .|||.. . .|       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

KLGAIDIVQLLKQTNGANSTTPIVAIT----NYFQEAATSRVFDDVLEKPVKLDELKKLV
..  |.... ..         ||...|        ..|     || . ||....|| . .
GMDGIELCRRIR---------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg RIM15.AA Response_reg 1637-1747 22 1.7e-09 36.59 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1637-1747
Range on HMM: 1-115/115
Sequence Identity: 22% (26 aa)

VLVCEPIPIHRYRVTKDLE-NLGC-TVVSVGAGDELVSRATSGVSFDLIMTALKLPKLGAIDIVQLLKQTNGANSTTPIVAIT-----NYFQEAATSRVF
||...  |. |  ... ||   |.  | ..  | |.. ..  .  .||| . . .|..  ... . . ....  ..|||...|     .. .||      
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-PDLIIMDINMPGMDGLELCRRIRRQHP-HPQTPIIMCTAHGDEDDAVEALQAG-A

DDVLEKPVKLDELKKLVA
.| . ||...|||.. ..
NDYITKPFDPDELHAAIR