Gene YAK1 (Bakers Yeast)

YAK1

Species: Bakers Yeast
Alias: YAK1
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: YAK

Sequence

Name Sequence Type Origin Length Description Download
YAK1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 257 Kinase domain by global Sugen HMM Fasta, JSON
YAK1.AA Protein Refseq_NP 807 Serine-threonine protein kinase; Yak1p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of YAK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase YAK1.AA YAK 369-704 56 4.7e-234 783.85 In-house 1-347 (347) Show / Hide 
Range on Protein: 369-704
Range on HMM: 1-347/347
Sequence Identity: 56% (197 aa)

YLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKH---HFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKF
|.|||.||||||||||||||..|.|..||||.|.|..|..|...|..||..|||..||.||.   |.|||||.||||||.|||||.|||||||.||||||
YIVLDMLGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKF

HGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFL
.|.|.||||..|.||||..|||.....||||||||||.||.|.|||.|||||||||.|...||||||.|.||.||||....|.|||||||||||||||||
CGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELFL

GIPIFPGASEYNQLTRIIDTLGYPPSWMIDMGKNSGKFMKKLAP----------EESSSSTQKHRMKTIEEFCREYNIVEKPSKQYFKWRKLPDIIRNYR
|.|||||.|||||..||||.|||||||||| |. . |. . .                       .|| ... ..  |  |.||.||.   |.||. .. 
GLPIFPGNSEYNQIKRIIDMLGYPPSWMIDQGRFKNKYFHCHDGSNSDDNNNNNNNNNGKPYYYIFKTKQDYQIDEKIQLKESKTYFQYKCLNDIKNYMY

YPKSIQNSQELIDQEMQNRECLIHFLGGVLNLNPLERWTPQQAMLHPFI
. ..  |  . .. . . |.|.|.|....|.|||.|||.|.|||.||||
FKQFMRN--QDDTKNNRHRDCFIDFINQLLQLNPRERWKPMQAMQHPFI
Kinase YAK1.AA DYRK 369-704 44 2.7e-173 582.0 In-house 1-320 (320) Show / Hide 
Range on Protein: 369-704
Range on HMM: 1-320/320
Sequence Identity: 44% (152 aa)

YLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGL
| .|...|.|.|||||||..  |.|..|.|..... ... |...| ||||.|||. ||..|.|...|||.|.|.||||.|||||| ||||.||.|.|.|.
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQ-DPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGF

-SIQLIRTFTTQILDSLCVLKES-KLIHCDLKPENILLCAP-DKPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFL
 |..|.|.|. |||..|..|... ..||||||||||.|. | .|...|.|||||||.|....|||||||||||||.|||.||...|||||||||.||||.
FSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFT

GIPIFPGASEYNQLTRIIDTLGYPPSWMIDMG--KNSGKFMKKLAPEESSSSTQKHRMKTIEEFCREYNIVEKPSKQYFKWRKLPDIIRNYRYPKSIQNS
| |.|||..||.||..|...||.||.|||| |  .   || ..                .  ..|.|    .|....|.  .. |. . ..|.|    ..
GWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC----------------FMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRP--PGRR

QELIDQEMQNRECLIHFLGGVLNLNPLERWTPQQAMLHPFI
     .. ........|. ..|...| .|.||.||. ||..
NWDPRHQ-CDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase YAK1.AA CMGC 369-704 23 2.2e-110 364.1 In-house 1-513 (513) Show / Hide 
Range on Protein: 369-704
Range on HMM: 1-513/513
Sequence Identity: 23% (124 aa)

YLVLDILGQGTFGQVVKCQN--------------LLTKEILAVKVVKSRTEYLTQSI-------------TEAKILELLNQKIDPTN---------KHH-
| ... .|.||.|.|.||..                |.|| |.| .|..  | .|                | |||. ||.. || |         ||| 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN

-FLRMYDSFVHKN-----------------HLCLVFELLSNNLYELLKQNK--------------------------FHGLSIQLIRTFTTQILDSLC--
  ...||.|.|||                 ||.||||.. ..||...|.|.                             ..| .|| .. ||| .|   
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

VLKESK--LIHCDLKPENILLCAP------------------DKPELKIIDFGSSC--EEA----------------------RTVYTYIQSRFYRAPEI
 .   .   ||.||||||||..                    .. .|||.|||...  ..                       |. ..|...|.||||||
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI

ILGIP----------YSTSIDMWSLGCIVAELFLG--------IPIFPGASE-----------YNQLTRIIDTLGYPPSWMIDMGKNSGKFMKKLAPEES
.|| .          |.|.|||||.||| ||...|         |.||| ||           ..|| .|...|| |. |||. || .  |       . 
LLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGK-RH-F-------N-

SSSTQKHRMKTIEEFCR--------------EYNIVEKPSKQY---FKWRKLPDIIRNYRYPKSIQNSQELIDQEMQNREC-------------------
 .. ..  .. |.   .              ....  .  .|    |.|.. ... . .   .  .. .      | .  .                   
FCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDD-N-NKK-AMVF-NWIYEEKFKSHKFNHQFKRKC

----LIHFLGGVLNLNPLERWTPQQAMLHPFI
    .|..| . | ..| .|.|..||. ||..
CDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase YAK1.AA DYRK2 369-595 48 2.7e-110 359.95 In-house 1-227 (318) Show / Hide 
Range on Protein: 369-595
Range on HMM: 1-227/318
Sequence Identity: 48% (110 aa)

YLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGL
| .| ..|.| |||||||    ||. .|.|..  .  .. |  .| .||. .  ..|..| .   .| |.|.  ||.|..||||| ||||..|.|.|.|.
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHI-RRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGF

SIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEAR-TVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGI
| ||.| |. .|| .|  |.. ..||||||||||||  . .  .|.||||||| | .  .|||||||||||||.|||..|...|||||.|||.|||. | 
SLQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGY

PIFPGASEYNQLTRIIDTLGYPPSWMID
|.|||  |  |.  ..  || ||. ..|
PLFPGENENDQFACMMEVLGMPPKKFFD
Kinase YAK1.AA HIPK 369-704 40 6.6e-100 315.35 In-house 1-329 (329) Show / Hide 
Range on Protein: 369-704
Range on HMM: 1-329/329
Sequence Identity: 40% (137 aa)

YLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGL
| ||..||.|||||||||    |.|. |.|. |    |  |   | .||. | |.    .  ||.|.|. | |||| |||||.|  |||. .|||||  |
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQEN--ADEYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPL

SIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKP--ELKIIDFGSSCEEARTVY-TYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFL
 .. ||. . |.|  |  |||  ||| |||||||.|  | .     |.|||||     ..|  ||.|||.|||||||||.|.  ..|||||||..|||||
PLKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFL

GIPIFPGASEYNQLTRIIDTLGYPPSWMIDMGKNSGKFMKKLAPEESSSSTQKHRMKTIEEFCREYNIVEKPSKQYFKWRKLPDIIRNYRYPKSIQNSQE
| | .|||.||.|   |. | . |   ..  .  . .| ...      |. .  |.|.|||   .  .  |  ..|     | |. ..  .    . .. 
GWPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFDRD----KQSKFRPWRLKHIEEHEQQTSVKSKEARKYI-FNCLDDMPEVN-MLVDPERQDY

LIDQEMQNRECLIHFLGGVLNLNPLERWTPQQAMLHPFI
..  |   |.  .| |  .. ... .| || .|. |||.
RV--EKIDRREFVHVLKKMCTWDAHKRITPCEALNHPFV
Kinase YAK1.AA DYRK1 369-629 43 1.8e-97 330.12 In-house 1-262 (321) Show / Hide 
Range on Protein: 369-629
Range on HMM: 1-262/321
Sequence Identity: 43% (114 aa)

YLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGL
|..   .|.| ||||||    ...|  |.|..| .  .. |   | ..|||.|.. |. .| . ...   |...||||||||||| |||.||.  .|.| 
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKH-DKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGV

SIQLIRTFTTQILDSLCVLK--ESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLG
|. |.| |  |.. .|  .   | ..||||||||||||| | .  .|||||||||.  . .| ||||||||.||..|||.|...|||||||||. |.  |
SLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTG

IPIFPGASEYNQLTRIIDTLGYPPSWMIDMGKNSGKFMKKLAPEESSSSTQKHRMKTIEEFCR
 |.| |..|  |...|.. || ||. ||| .  . |. .|.  .  .   .. . |. .|.|.
EPLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYFEKDPDNTWYCKKTRDKKKHYKEPCT
Kinase YAK1.AA S_TKc 369-704 21 6.4e-83 282.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 369-704
Range on HMM: 1-231/231
Sequence Identity: 21% (75 aa)

YLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSN---NLYELLKQNKF
| .|...|.|.||.| ||..  |..| |.|..|       . . | .||.         .  .  ..||.|.. .||..|.|....   .|....|... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

HG----LSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYST-SIDMWSLGCIV
||    ..   .| .. ||.. |  . . . ||.|||||||||.     ..||.|||....     .|.. ...|.|||..   .|.. ..|.||.|||.
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

AELFLGIPIFPGASEYNQLTRIIDTLGYPPSWMIDMGKNSGKFMKKLAPEESSSSTQKHRMKTIEEFCREYNIVEKPSKQYFKWRKLPDIIRNYRYPKSI
.|.. | | ||      |. .... .|                                                                         
YEMLCGYPPFP------QMQMMFKKIG-------------------------------------------------------------------------

QNSQELIDQEMQNRECLIHFLGGVLNLNPLERWTPQQAML-------HPFI
              . ...|. . |. .| .|.|  .|.        ||..
-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase YAK1.AA DyrkP 369-598 41 3.4e-62 203.38 In-house 1-233 (323) Show / Hide 
Range on Protein: 369-598
Range on HMM: 1-233/323
Sequence Identity: 41% (97 aa)

YLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNK----
| ... ||   | . ..|| . |  .. .|..    .|  ||| | |.|  .|   |   |   ||.|| | || || .. ||| .||||  | |.    
YQIMEYLGSAAFSKAIQCQDKQTNQMMCMKIIENNKDYFDQSIDEIKLLRYINYNGDVDEK-NVLRYYDYFYHKEHLFIITELLKDNLYEFYKFNRENEQ

FHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELF
     .  .   | ||| .|  .   .||||||||||||. .  | . |||||||||     .  |.||| |||||.|.|  |   |||||||||.|||.
QRYFTVGRLQKITQQILIALDYIHSLRLIHCDLKPENILMKSYPKCQVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELW

LGIPIFPGASEYNQLTRIIDTLGYPPSWMIDMGK
 |  .|        | |.|  .|  | ||.  |.
TGNVLFQNDNIQGLLARVIGIIGPFPEWMMQEGR
Kinase YAK1.AA PRP4 369-572 40 4.5e-60 205.88 In-house 1-207 (320) Show / Hide 
Range on Protein: 369-572
Range on HMM: 1-207/320
Sequence Identity: 40% (84 aa)

YLVLDILGQGTFGQVVKCQ-NLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQK-IDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQN-KF
| |    ||| |. |..|. .  ..|  |.|.. ..         |  ||  || .  |.  | | .||...| |..|.||||| .| || |.||.  | 
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKYGKD

HGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCE-EARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELF
 ||..  .| .. |..  |  || .. .| |.|| |||    .|  ||..||||  . .   .  | .||||||||||.|.||  .||||| ||  .||.
VGLHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNILVNE-SKNTLKMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYELY

LGIPIFPG
 |  .|||
TGKIMFPG
Kinase YAK1.AA Pkinase 369-595 30 2e-56 198.56 Pfam 1-240 (293) Show / Hide 
Range on Protein: 369-595
Range on HMM: 1-240/293
Sequence Identity: 30% (77 aa)

YLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSIT-----EAKILELLNQKIDPTNKH-HFLRMYDSFVHKNHLCLVFELLSN-----NLY
| .. ..|.|.||.| ||..  | .| |||..| |.|   . .|     |..|.  ||        | . .|.||.|  |.|...|.|.. .      |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN--------HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF

ELLK---QNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPEL----KIIDFGSSC---EEARTVYTYIQSRFYRAPEIIL-GIP
....   ...|  .| . .. . .|||  |  . . . ||.||||||||.   .....    ||.|||...   .  .  .|.  ...|.|||.|. | .
DYISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQY

YSTSIDMWSLGCIVAELFLGIPIFPGA----SEYNQLTRIIDTLGYPPSWMID
|....||||.|||..|...| |.|||.    . ..|. .|  ..| |... ..
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWP
Kinase YAK1.AA CLK 369-505 33 1.5e-51 152.4 In-house 1-148 (350) Show / Hide 
Range on Protein: 369-505
Range on HMM: 1-148/350
Sequence Identity: 33% (49 aa)

YLVLDILGQGTFGQVVKCQNLLT-KEILAVKVVKSRTEYLTQSITEAK-ILELLNQKIDPTNKHH--FLRMYDSFVH-KNHLCLVFELLSNNLYELLKQN
| ... ||.|||| ||.|.     |   |.|.... ..|  .. .| . |.. .|.| || ||.    ..|.|.| . ..| |.||||.  ..|...| |
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN

K------FHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLC
.      . .. |. || .. |.. ... | . ||.| |||||||...
NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICFV
Kinase YAK1.AA CDK 434-589 31 1.4e-42 133.95 In-house 71-244 (284) Show / Hide 
Range on Protein: 434-589
Range on HMM: 71-244/284
Sequence Identity: 31% (59 aa)

RMYDSFVHK-----------NHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPE---LKIIDFGS
. .| ...|           | | .||| .   |.....           |.... |.|. |  . . . .| |||| |||.    ...   ||| ||| 
KLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD-----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGL

SCEEA--------RTVYT-YIQSRFYRAPEIIL-GIPYS--TSIDMWSLGCIVAELFL---GIPIFPGASEYNQLTRIIDTLGYP
...          . .||  .  . |||||. |    ||  |.|||||.||| ||.|.   . |.||| || .|| .|....| |
ARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTP
Kinase YAK1.AA CLK 510-572 39 2.7e-20 56.9 In-house 184-249 (350) Show / Hide 
Range on Protein: 510-572
Range on HMM: 184-249/350
Sequence Identity: 39% (26 aa)

PELKIIDFGSSC---EEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIFPG
.. ..|||||      .    .| ...| |||||.||| ..|.  | || |||  || .|.  |..
THICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQT
Kinase YAK1.AA CDK 369-401 31 4.2e-10 28.36 In-house 1-38 (284) Show / Hide 
Range on Protein: 369-401
Range on HMM: 1-38/284
Sequence Identity: 31% (12 aa)

YLVLDILGQGTFGQVVKCQNLLTK-----EILAVKVVK
|  |. .|.||.|.| |.....|.     .| | | ..
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIR
Kinase YAK1.AA TyrKc 369-621 20 9.9e-09 -81.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 369-621
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

YLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELL---NQKIDPTNKHHFLRMYDSFVHK-------NHLCLVFELLSN-NLY
   ...|| | ||.|.|..     .  |||..|. .  .   . ||.|.  |   .. |        .|.|   ...         |..|.|. .. .| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNI--------VRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

ELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEART-------VYTYI----QSR-----FYRAPEI
. |. .. . |. .    | .|| .    | . ..|| ||   |.|. ..     || ||| | .            |       ...        ||| 
DYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

ILGIPYSTSIDMWSLGCIVAELF-LGIPIFPGA----SEYNQLTRIIDTLGYPPSWMID-------MGKNSGKFMKK---LAPEE-SSSSTQKHRM
|    ..|  | || |    |.| .| .  ||      .  .. . ... ...|    |       . .   . ||.     ||.  . |. ....
INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase YAK1.AA CDK 644-704 19 2e-06 16.09 In-house 252-284 (284) Show / Hide 
Range on Protein: 644-704
Range on HMM: 252-284/284
Sequence Identity: 19% (12 aa)

WRKLPDIIRNYRYPKSIQNSQELIDQEMQNRECLIHFLGGVLNLNPLERWTPQQAMLHPFI
. ||||                             ..| . | ..|  |.. .||. ||. 
VTKLPDY----------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase YAK1.AA DYRK2 675-704 43 5e-06 15.15 In-house 289-318 (318) Show / Hide 
Range on Protein: 675-704
Range on HMM: 289-318/318
Sequence Identity: 43% (13 aa)

ECLIHFLGGVLNLNPLERWTPQQAMLHPFI
| .| |.  ..   | || ||.||  ||.|
ENFIDFIKRCFEWDPSERMTPSQALKHPWI
Kinase YAK1.AA PRP4 660-704 31 2.2e-05 15.79 In-house 276-320 (320) Show / Hide 
Range on Protein: 660-704
Range on HMM: 276-320/320
Sequence Identity: 31% (14 aa)

IQNSQELIDQEMQNRECLIHFLGGVLNLNPLERWTPQQAMLHPFI
|.. | . ...|.    .  .| ..| | |  | |. .|  ||||
IECNQRIPEDQMKKVHQFKDLLDKCLMLDPKKRITCNEALKHPFI
Kinase YAK1.AA Pkinase 677-704 28 3e-05 19.63 Pfam 266-293 (293) Show / Hide 
Range on Protein: 677-704
Range on HMM: 266-293/293
Sequence Identity: 28% (8 aa)

LIHFLGGVLNLNPLERWTPQQAMLHPFI
...|. . |...| .|.|..|.. ||..
CKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase YAK1.AA DYRK1 684-704 38 0.063179 1.97 In-house 301-321 (321) Show / Hide 
Range on Protein: 684-704
Range on HMM: 301-321/321
Sequence Identity: 38% (8 aa)

VLNLNPLERWTPQQAMLHPFI
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MLQYDPKQRITPYYALQHSFF