Gene YCK1 (Bakers Yeast)
YCK1
Sequence
Protein domains of YCK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | YCK1.AA | CK1-G | 69-331 | 71 | 8.8e-218 | 729.79 | In-house | 1-266 (266) | Show / Hide |
Range on Protein: 69-331 Range on HMM: 1-266/266 Sequence Identity: 71% (189 aa) YKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRKTEAPQLRDEYKTYKILNGTP-NIPYAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRKFSVKTVVQ |..|||||.|.||.||||.||.|...|||||||.|..||||.|||..||||||.| .||..|||||.|..||.|.||||||||||||||.||||||||.. YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFDWCDRKFSVKTVCM VAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFY ||.|||...|..|.|.|||||.||||||||||...|...||.|||||||||.||.|||||||||.|||.|||||||||||||||||||||||||||.|.| VAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMFMY FLRGHLPWQGLKAPNNKQKYEKIGEKKRSTNVYDLAQG--LPVQFGRYLEIVRSLSFEECPDYEGY ||||.||||||||.|||..|.|||..||.||..||.|. .|.||..||..||.|.|.|||||. FLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL |
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Kinase | YCK1.AA | CK1 | 69-329 | 59 | 2.8e-184 | 618.5 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 69-329 Range on HMM: 1-271/271 Sequence Identity: 59% (162 aa) YKIGKKIGEGSFGVLFEGTNMINGVP--VAIKFEPRKTEAPQLRDEYKTYKILNG------TPNIPYAYYFGQE--GLHNILVIDLLGPSLEDLFDWCGR |..|.|||.||||....|.|| ||. ||||.|..|...||| .|.| ||||.| ..|| |..||| | .||.|.|||||||||||..|.| YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFCNR KFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDM |||.|||. .| |||. || .| ...|.|||||||||.|| .. .......||||.||.|||.||.|||||||.|.| |||||.|||||||.|||||||| KFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGR-YGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDM EALGHVFFYFLRGHLPWQGLKAPNNKQKYEKIGEKKRSTNVYDLAQG-LPVQFGRYLEIVRSLSFEECPDYE |.||.|..|||||.||||||||...|||||||.|||.||.|..| .| .|..| .||...|.|.|||.|||. ESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM |
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Kinase | YCK1.AA | CK1-Unclassified | 69-303 | 53 | 2.9e-144 | 428.66 | In-house | 1-244 (244) | Show / Hide |
Range on Protein: 69-303 Range on HMM: 1-244/244 Sequence Identity: 53% (131 aa) YKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRKTEAPQLRDEYKTYKILNGTP-------NIPYAYYFGQE--GLHNILVIDLLGPSLEDLFDWCGRK |....||| |||| ....|| .. ||||.| .... ||| | | ...|.. .|| |..||| | .||.| ||||||||||| |.|| YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCNRK FSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIG-RPGQPDANNIHLIDFGMAKQYRDP-KTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDD ||.||| | |||. || || . .|.|||||||||.| . .. ......|||| .| |.|. ||..||||||.|.| ||||| |||.||| ||||||| FSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKN--HHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDD MEALGHVFFYFLRGHLPWQGLKAPNNKQKYEKIGEKKRSTNVYDLA .|.|| |. |||.|.||||..|| | |.||||| |.| || | | LESLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC |
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Kinase | YCK1.AA | CK1-D | 69-331 | 56 | 1.1e-125 | 423.82 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 69-331 Range on HMM: 1-261/261 Sequence Identity: 56% (148 aa) YKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRKTEAPQLRDEYKTYKILNGTPNIPYAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRKFSVKTVVQV |.||.||| |||| .. |||.... |||| |. ||. ||| | | ||...| || ..|||| |..|.||||||||||| .|.||||.|||. . YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHRKFSLKTVLML AVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYF | |||. || .|... | |||||||||.| . | ...||||.||.|||..|.|||||||.|.| ||||| |||||.| |||||||.|.|| |. || ADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKR--GNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYF LRGHLPWQGLKAPNNKQKYEKIGEKKRSTNVYDLAQGLPVQFGRYLEIVRSLSFEECPDYEGY || |||||||| . .||||.| ||| ||.. .| .|.| .| .|.. .|.| |.. ||| NRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL |
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Kinase | YCK1.AA | CK1 | 69-331 | 36 | 4.4e-123 | 415.21 | In-house | 1-339 (339) | Show / Hide |
Range on Protein: 69-331 Range on HMM: 1-339/339 Sequence Identity: 36% (123 aa) YKIGKKIGEGSFG-VLFEG-----TNMING-----VPVAIKFEPRKTE--APQLRDEYKTYKILNGT-------------------PNIPYAYYFGQEGL .|..||||||.|| ... ..| |. .|.| ||.|.. ||| .||. ||.|.| .| .|....|. WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED --HNILVIDLLGPSLEDLFD---WCGRKFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQ-----------PDANNIHLIDFGMAK-QYR .|..|..||||.||||.. .|.||||.||....|.||. .|..| . |.||||||||..|| .. ........||||||. .|| DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR DP-----------KTKQHIPYRE---KKSLSG-TARYMSINTHLGREQSRRDDMEALGHVFFYFLRGH--LPWQGLKAPNN-------KQKYEKIGEKKR |. ||.||.|.|| ||.. | ||||.|||.|||.||.||||...........|.|. ||||..|.... |.|||.| ||| DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM STNVYDLAQG-----LPVQFGRYLEIVRSLSFEECPDYEGY || .. | . .| .| .....|||.... |||| STPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI |
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Kinase | YCK1.AA | CK1-A | 69-331 | 55 | 1.9e-117 | 396.5 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 69-331 Range on HMM: 1-261/261 Sequence Identity: 55% (147 aa) YKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRKTEAPQLRDEYKTYKILNGTPNIPYAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRKFSVKTVVQV |.. .||| |||| .. | |. || |||| | .| ||| | | |.||.| . || ..|.| .|..|.||||||||||| | |.|..|||. . YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKRRFTMKTVLML AVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYF | |||. || .| . | |||||||||.| | ..|||||.||.|||..|.||||||| | | ||||| ||| ||| |||||||||..| |. || ADQMIMRIEYVHEKNFIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYF LRGHLPWQGLKAPNNKQKYEKIGEKKRSTNVYDLAQGLPVQFGRYLEIVRSLSFEECPDYEGY ||.|||||.|| . ||||||| ||| || . | .| | .| |.. .|.| ||| ||| NRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL |
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Kinase | YCK1.AA | TTBKL | 69-335 | 27 | 7.6e-45 | 149.36 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 69-335 Range on HMM: 1-288/288 Sequence Identity: 27% (80 aa) YKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRKT-EAPQLRD--EYKTYKILN--GTPNIPYAYYFGQEGLHNILVIDLLGPSLEDLF-DWCGRK-FS ..| |.|||| ||. ... .| . .|.. |. .. | | | . . |. | | .| .. |... | .| |.||.| || . . .| || WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS VKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQ--PDANNIHLIDFGMAKQYRDP----------KTKQHIPYRE---KKSLSGTARYMSINT . |.. ...| . . ..| . | ||.|| |. .| .. ... ...|||||||.||... ..... . |. | .. || ||.|.| DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM HLGREQSRRDDMEALGHVFFYFLRGHLPWQGLKAPNNKQKYEKIGEKKRSTNVYDLAQG------LPVQFGRYLEIVRSLSFEECPDYEGYRKLL |...||.| ||. .. .. ... | |||.... . ..|...|.... ||... .| .|. . .|||.. . |||| .... HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDK------MEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF |
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Kinase | YCK1.AA | TTBK | 69-331 | 33 | 1.9e-42 | 147.31 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 69-331 Range on HMM: 1-257/257 Sequence Identity: 33% (89 aa) YKIGKKIGEGSFGVLFEGTNMING-VPVAIKFEPRKTEAPQLRDEYKTYKILNGTPNIPYAYYFGQEGLHNILVIDLLGPSLEDLFDWCGR-KFSVKTVV |. |||| | || .|...||| |||| | .. |. | | | | . . . | . | .| .|.| .| || | .||. | . WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTL QVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFF .. ||.. || | ||||| || .|| . ... ..|||.| || . | || ||.|| ||| |. || |.||. | . RLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPS-TCRKCYMLDFGLARQYTNACGEVRPP-REVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLV YFLRGHLPWQGLKAPNNKQKYEKIGEKKRSTNVYDLAQGLPVQFGRYLEIVRSLSFEECPDYEGY |. | ||| .| ...|| | . .| . .| .| ... ..|| .|. ||| EFVQGQLPWRKIKD------KDQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI |
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Kinase | YCK1.AA | Worm6 | 140-331 | 29 | 1.9e-37 | 130.74 | In-house | 80-279 (279) | Show / Hide |
Range on Protein: 140-331 Range on HMM: 80-279/279 Sequence Identity: 29% (60 aa) LVIDLLGPSLEDLFDWC-GRKFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGR---PGQPDANNIHLIDFGMAK--QYRDPKTKQHIPYR-EK .|. |.|..|.|| . .||||. | ..| |.. ||||| . | ||.|| || ||| . . .| ..||||.. .|.. | .. .. | .. IVMTLVGKNLWDLRKNRPDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCN-KGNELRTPRWTA KSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGHLPWQGLKAPNNKQ-KYEKIGEKKRSTNVYDLAQGLPV-QFGRYLEIVRSLSFEECPDYEG || ||.... | |.||.|.||.| . ...| |||...|...... .... ..|.. .. .. | .| . .... ..|... |||. CGFRGTVRYAPLACHKGQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKF Y I |
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Kinase | YCK1.AA | Pkinase | 69-294 | 25 | 1.3e-33 | 119.96 | Pfam | 1-234 (293) | Show / Hide |
Range on Protein: 69-294 Range on HMM: 1-234/293 Sequence Identity: 25% (62 aa) YKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRKTEAPQLRD------EYKTYKILNGTPNIPYAYYFGQEGLHNILVIDLLGPSLEDLFDWC------ |.||.|||.||||. ..... .| ||.| ....| .. . | . | | . ||| |.. ... | .| .... |. ..| . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTW -GRKF--SVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHL-GREQ ...| | ... .. |.. .| .|.. |.||.||.|.|| . |..|| ....||| |||.. . ... ... || .||. .. |.. RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIRGGQYY SRRDDMEALGHVFFYFLRGHLPWQGL----KAPNNKQKYEKIGEKK ... || ..| .....| |..|..| . . .|....|.... GPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPP |
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Kinase | YCK1.AA | S_TKc | 69-353 | 20 | 1.1e-18 | 69.29 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 69-353 Range on HMM: 1-231/231 Sequence Identity: 20% (63 aa) YKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRKTEAPQLRDEYKTYKILNGTPNIPYAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRK--------F |.|..|||.|.||. . ... | |||| . ..| | . | . ||| |.. |. | .| .... .| |||| .. | YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF SVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSR-RDDME . .. .. |.. .| .| | |.||.||.| |. . .| ..|||.|.|. ... || ||. .. . |. PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDWW ALGHVFFYFLRGHLPWQGLKAPNNKQKYEKIGEKKRSTNVYDLAQGLPVQFGRYLEIVRSLSFEECPDYEGYRKLLLSVLD-D----LGETADGQ----- ..| ... .| | |.. . .. ..||| . |. .. |. | .. | SCGCILYEMLCGYPPFP-----QMQMMFKKIG-----------------------------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDI --YDWM |. KCHPWF |
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Kinase | YCK1.AA | Dual | 140-260 | 31 | 1.3e-18 | 59.05 | In-house | 89-208 (282) | Show / Hide |
Range on Protein: 140-260 Range on HMM: 89-208/282 Sequence Identity: 31% (39 aa) LVIDLLGPSLEDLFD-WCGRKFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDPKTKQHIPYREKKSLSGT .|. . ||||.. .|. . || ||.. | ||| . |.||| || .| | . . ||.... | ||..|.| . | | |. WVMSPYGPSLQEIRRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGL--GMDETTVYMQDFRIVRKYIDPENKKHRTARKKVKMYGC ARYMSINTHLGREQSRRDDMEA .|| .. . ..| | ||.|. GRYACRACMMQKDQGRKDDLEC |
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Kinase | YCK1.AA | Worm6 | 69-110 | 27 | 1.6e-05 | 16.11 | In-house | 1-46 (279) | Show / Hide |
Range on Protein: 69-110 Range on HMM: 1-46/279 Sequence Identity: 27% (13 aa) YKIGKKIGEGSFGVLFEGT---NMINGVPVAIKFEP--RKTEAPQLR .|..||||||.|| .. . .. . ...|.| | .. . ..|. WKVTKKIGEGGFGAVYKVEDKSDKKK-KQFAMKCEKQMENMKRQMLK |
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Kinase | YCK1.AA | TyrKc | 69-290 | 17 | 0.000191 | -150.75 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 69-290 Range on HMM: 1-280/280 Sequence Identity: 17% (52 aa) YKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRKTEAPQLRDEYKTYKIL-NGTPNIPYAYYFGQEGL------HNILVIDLLGP--SLEDLFDWCGRK . |||.||| ||. ..|| ..||.| . ...| . . | ||| | .. . .... . | .| | ...| ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK FSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDP----KTKQHIPYREKKSLS--GTARYM---SINTH--- ...|. .. ..| | || . .| ||. | |.|... . |||... | |. . .|.|. | | .||.. LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT -----------------LGREQSRR-----DDMEALGHVFFYFLRGHLPWQGLK--------APNN-------------------KQKYEKI .| . . . .|. | .|. . | .| .. .|.. TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQ---EVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | YCK1.AA | Pkinase_Tyr | 69-98 | 41 | 0.000899 | 13.4 | Pfam | 1-34 (270) | Show / Hide |
Range on Protein: 69-98 Range on HMM: 1-34/270 Sequence Identity: 41% (14 aa) YKIGKKIGEGSFGVLFEGTNM----INGVPVAIK ..|||.|||.||. ..|| ...|||.| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVK |
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Kinase | YCK1.AA | Dual | 314-335 | 27 | 0.244638 | 0.1 | In-house | 261-282 (282) | Show / Hide |
Range on Protein: 314-335 Range on HMM: 261-282/282 Sequence Identity: 27% (6 aa) LEIVRSLSFEECPDYEGYRKLL . | ..... |||. | | VSYVNGYQYDSTPDYDYFRNCL |