Gene YCK3 (Bakers Yeast)

YCK3

Species: Bakers Yeast
Alias: YCK3
External Links: Saccharomyces Genome Database Link
Annotation:

Classification

Group: CK1
Family: CK1
Subfamily: CK1-G

Sequence

Name Sequence Type Origin Length Description Download
YCK3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 296 Kinase domain by global Sugen HMM Fasta, JSON
YCK3.AA Protein Refseq_NP 524 plasma membrane-bound casein kinase I homolog; Yck3p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of YCK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase YCK3.AA CK1-G 14-311 62 1.5e-215 722.36 In-house 1-266 (266) Show / Hide 
Range on Protein: 14-311
Range on HMM: 1-266/266
Sequence Identity: 62% (188 aa)

YAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSDAPQLRDEFRAYRILNGCV-GIPHAYYFGQEGMHNILIIDLLGPSLE
|.||.|||.|.||..|||.|...                 ||.|||||||..|.||||.||.|.|.|||||. |||..|||||.|..||...||||||||
YRVGKKIGCGNFGELFEGKNMYN-----------------NEHVAIKFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLE

DLFEWCGRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAKQYRDPRTKQHIPYRERKS
|||.||.|||||||.||||.|||.|....|.|.|||||.|||||||..                .||.|...|...||||||||.||.|||||||||.||
DLFDWCDRKFSVKTVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGR----------------PSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKS

LSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPYQFATYLKYARSLKFDEDPDYDYL
|.|||||||||||.|||||||||.|.|||.|.||||||||||||||.|||..|.|||.||.|.|..||. |||.|.||||||.|.|.|.|.|.||||||
LTGTARYMSINTHLGREQSRRDDMEALGHMFMYFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase YCK3.AA CK1 14-309 50 1.7e-175 589.35 In-house 1-271 (271) Show / Hide 
Range on Protein: 14-309
Range on HMM: 1-271/271
Sequence Identity: 50% (153 aa)

YAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSDAPQLRDEFRAYRILNG------CVGIPHAYYFGQE--GMHNILIID
| || |||.||||.|..|.|. .....             | .||||.|...| .||| .| . |.||.|      |.|||| |..|||  |..||...|
YRVGRKIGQGSFGDIYLGINM-TNGEE-------------N-HVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMD

LLGPSLEDLFEWCGRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAKQYRDPRTKQHI
|||||||||| .|.||||.||..|.| |||.|.  .| ...|.|||||||||.                   .... . .|..|||.||.|||..|.|||
LLGPSLEDLFNFCNRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGR-----------------YGKHCHQVYIIDFGLAKRYRDDKTHQHI

PYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPYQFATYLKYARSLKFDED
|||| |.| |||||.||||| |.|||||||.||||.|..||||||||||||||...| |||||...|.......|  .| .|..||.||.|.|.|.|.|.
PYRENKNLTGTARYASINTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGN-FPNEFAMYLNYCRQLHFEEK

PDYD
|||.
PDYM
Kinase YCK3.AA CK1-Unclassified 14-281 46 1.7e-126 375.33 In-house 1-244 (244) Show / Hide 
Range on Protein: 14-281
Range on HMM: 1-244/244
Sequence Identity: 46% (129 aa)

YAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIM-ANEPVAIKFEPRHSDAPQLRDEFRAYRILNGCV-------GIPHAYYFGQE--GMHNILI
| |. ||| |||| |...                  | |  || ||||.| . |  |||  | . ...|...        |||. |..|||  | .||..
YRVIEKIGQGSFGEIYKC------------------INMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMV

IDLLGPSLEDLFEWCGRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAKQYRDP-RTK
 |||||||||||  |.||||.||. | | |||.|.  .| . .|.|||||||||. .                 ...  . .|..||| .| |.|. .|.
MDLLGPSLEDLFNMCNRKFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGK-----------------LGKNHHQVYIIDFGLSKRYIDMDKTG

QHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLL
.|||||| |.| ||||| |||.| | |||||||||||| |. |||.||||||..|| | | |||||   |. . .. | 
KHIPYRENKNLTGTARYASINAHLGIEQSRRDDLESLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC
Kinase YCK3.AA CK1 14-311 31 5e-116 391.77 In-house 1-339 (339) Show / Hide 
Range on Protein: 14-311
Range on HMM: 1-339/339
Sequence Identity: 31% (116 aa)

YAVGPKIGEGSFG-VIFEG-----ENILHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSD--APQLRDEFRAYRILNGC-------------------VG
. |. |||||.||  |...     ...  . ..            ..| .|.| ||..|    ||| .|.. |..|.|.                   ..
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPY------------KGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCP

IPHAYYFGQEGM--HNILIIDLLGPSLEDLFE---WCGRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNND
.|..|....|.   .|.....||||.||||..   .|.||||.||. |.| ||..... .||.  |.||||||||... ....            .....
HPCMYWYHGEEDDYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESF------------KYGKH

PN--------LIYMVDFGMAK-QYRDP-----------RTKQHIPYRE---RKSLSG-TARYMSINTHFGREQSRRDDLESLGHVFFYFLRGS--LPWQG
 .         .||.|||||. .|||.           .|.||.|.||   .|.. | ||||.|||.| |.||.|||||.|........|.|.  ||||.
-HHEWNNEHRQVYMIDFGMARRKYRDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQN

LKAPNN-------KLKYEKIGMTKQKLNPDDLLLNNA---IPYQFATYLKYARSLKFDEDPDYDYL
.|....       | |||.|  .| .. .. |  .     .| .| ...|| ||||... |||...
MKDEMKPKDHQVEKMKYEFIDEKKMSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase YCK3.AA CK1-A 14-311 47 7.29999999999e-102 344.71 In-house 1-261 (261) Show / Hide 
Range on Protein: 14-311
Range on HMM: 1-261/261
Sequence Identity: 47% (141 aa)

YAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSDAPQLRDEFRAYRILNGCVGIPHAYYFGQEGMHNILIIDLLGPSLED
| .  ||| |||| |. | |                 |   | |||| | ..   |||  | . ||||.|||||||  ..|.|  .|....|||||||||
YRLVRKIGSGSFGDIYLGIN-----------------ITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLED

LFEWCGRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAKQYRDPRTKQHIPYRERKSL
||  | |.|..||  |.| ||| |.  .| .  | |||||||||.                          ....|||.||.|||.||.||||||| | |
LFNFCKRRFTMKTVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCN------------------KLFLIDFGLAKKYRDSRTRQHIPYREDKNL

SGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPYQFATYLKYARSLKFDEDPDYDYL
 ||||| ||| | | |||||||.||.| |. || ||.|||||.|| . | |||||   |     . |      | .|. |..|.|.|.|.| ||| ||
TGTARYASINAHLGIEQSRRDDMESMGYVMMYFNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLC--KGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase YCK3.AA CK1-D 183-311 60 4.5e-62 212.53 In-house 135-261 (261) Show / Hide 
Range on Protein: 183-311
Range on HMM: 135-261/261
Sequence Identity: 60% (78 aa)

NLIYMVDFGMAKQYRDPRTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLL
|..|..|||.||.|||.||.||||||| |.| ||||| ||||| | |||||||||||| |. || ||||||||||| . . |||.|  . .|..     |
NMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNRGSLPWQGLKAATKRQKYERI--CEKKMSTKIDTL

NNAIPYQFATYLKYARSLKFDEDPDYDYL
 .  | .|..|. |.|.||||. ||| ||
CKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase YCK3.AA CK1-D 14-158 48 3.7e-49 169.63 In-house 1-128 (261) Show / Hide 
Range on Protein: 14-158
Range on HMM: 1-128/261
Sequence Identity: 48% (70 aa)

YAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSDAPQLRDEFRAYRILNGCVGIPHAYYFGQEGMHNILIIDLLGPSLED
| .| ||| |||| |. |.|                 | .|| |||| |. ..  |||  | . |....| .|||.  ..||||  |....|||||||||
YRIGRKIGSGSFGDIYHGTN-----------------IQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLED

LFEWCGRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLI
|| .|.||||.||  |.| ||| |.  || .. | |||||||||.
LFNYCHRKFSLKTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLM
Kinase YCK3.AA TTBK 14-311 29 3.2e-32 111.18 In-house 1-257 (257) Show / Hide 
Range on Protein: 14-311
Range on HMM: 1-257/257
Sequence Identity: 29% (89 aa)

YAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSDAPQLRDEFRAYRILNGCVGIPHAYYFGQEGMHNILIIDLLGPSLED
  |  ||| | || |.|...                .|   | |||| |  .     |. |    . | ||  .   .  | .   | .. .|.| .| |
WKVVKKIGGGGFGEIYEAKD----------------MINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLAD

L-FEWCGRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAKQYRDPRTKQHIPYRERKS
|  .    .||. ||  . .|... ...||.     ||||| || .         |.. . |        . .||.|||.| ||         | ||   
LRRKQPRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAM---------GRNPSTC--------RKCYMLDFGLARQYTNACGEVRPP-REVAG

LSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPYQFATYLKYARSLKFDEDPDYDYL
  ||.|| ||| |  ||  |.||| ||  .   |. | |||  .|        ...|..|.| .  .||  . .| .| ....  .||.. . |||  .
FRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVQGQLPWRKIKD------KDQVGEMKEKYDHRMLL--KHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase YCK3.AA Worm6 102-311 27 8.1e-31 107.88 In-house 80-279 (279) Show / Hide 
Range on Protein: 102-311
Range on HMM: 80-279/279
Sequence Identity: 27% (59 aa)

LIIDLLGPSLEDLFEWC-GRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAK--QYRD
... |.|..|.|| . . .||||. |.  .| |......  | .  | ||.|| || | .||               ..|.   |||.||||..  .|..
IVMTLVGKNLWDLRKNRPDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQ------------M-KEDNEHHTIYMLDFGMCRRKKYCN

PRTKQHIPYR-ERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPY-QFATYLKY
 . .. .. | ..    || ||.... | |.||.|.||.||   .   ...| |||...|..... |. |  . . .     ..... .|. .|   ..|
-KGNELRTPRWTACGFRGTVRYAPLACHKGQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGP-CPKEEFNDIMDY

ARSLKFDEDPDYDYL
  .... ..|||...
IDQYSYWDRPDYKFI
Kinase YCK3.AA Pkinase 14-272 17 2e-29 105.14 Pfam 1-234 (293) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-234/293
Sequence Identity: 17% (50 aa)

YAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSDAPQLRD------EFRAYRILNGCVGIPHAYYFGQEGMHNILIIDLL
| .| |||.||||. ... ..  ..                  ||.|  ..... .. .       | .  . || .  .   ..|   . |  .. ...
YHIGRKIGSGSFGCVYKCHHKGTGK-----------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYC

GPSLEDLFEWC-------GRKF--SVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAKQYRD
.  |. ... .       ...|  | .. .....|..  .  .|..  |.||.||.|.||..   |..                  .   ||| |||.. 
EGGLY-VMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-----------------CVKICDFGLAKQFD-

PRTKQHIPYRERKSLSGTARYMSINTHF-GREQSRRDDLESLGHVFFYFLRGSLPWQGL----KAPNNKLKYEKIGMTK
     . ...  ... || .||.   .  |.. ... |  |.| .....| | .|..|     .  . . ....|....
-----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPP
Kinase YCK3.AA TTBKL 87-315 25 3e-27 89.1 In-house 62-288 (288) Show / Hide 
Range on Protein: 87-315
Range on HMM: 62-288/288
Sequence Identity: 25% (62 aa)

IPHAYYFGQEGMHNILIIDLLGPSLEDLFEWCGRK--FSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNL
.|. .. |...  | ..  |.||.| ||     .|  ||. |.  .. | .. .. .||.  | ||.|| |. .  ... ... ..              
FPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRH--------------

IYMVDFGMAKQYRDPRT----------KQHIPYRE---RKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKAPNNKLKYEKIGMT
.| .|||||.||...            ... . |.   . .. || ||.|.| | ..||.| ||| |.  .. ... | |||.... .      ..|. .
VYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNMHDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDK------MEIEHM

KQKLNPDDLLLNNA----IPYQFATYLKYARSLKFDEDPDYDYLISLM
|.... .||  .      .| .|.   |. |||.. . |||.... ..
KKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase YCK3.AA S_TKc 14-333 15 2e-14 34.47 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-333
Range on HMM: 1-231/231
Sequence Identity: 15% (53 aa)

YAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSDAPQLRDEFRAYRILNGCVGIPHAYYFGQEGMHNILIIDLLGPSLED
| .. |||.|.||. . . ..                   .. ||||  .      ..| | .  .   ..  | . |.. |.  |  .. .... .| |
YEILRKIGKGAFGKVYKCRHKK-----------------TGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGD

LFEWCGRK--------FSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAKQYRDPRTKQHI
||.   ..        |.  ... ...|... .  .|.|  |.||.||.| |...                        |   |||.|.|.         
LFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----------------------HIKICDFGLARQL---------

PYRERKSLSGTARYMSINTHFGREQSR-RDDLESLGHVFFYFLRGSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPYQFATYLKYARSLKFDE
     ... ||  ||.         .. . |  |.| ... .| |  |..     . .. ..|||                                   
-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG-----------------------------------

DPDYDYLISLMDDALRLN-----DLKDDGH-------YDWM
    . ......  |. .        .  .         |.
---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase YCK3.AA Dual 185-238 35 7e-12 36.11 In-house 155-208 (282) Show / Hide 
Range on Protein: 185-238
Range on HMM: 155-208/282
Sequence Identity: 35% (19 aa)

IYMVDFGMAKQYRDPRTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLES
.|| ||.... | || .|.| . |      |..|| ..     ..| | ||||.
VYMQDFRIVRKYIDPENKKHRTARKKVKMYGCGRYACRACMMQKDQGRKDDLEC
Kinase YCK3.AA TTBKL 14-34 28 0.000167 11.2 In-house 1-21 (288) Show / Hide 
Range on Protein: 14-34
Range on HMM: 1-21/288
Sequence Identity: 28% (6 aa)

YAVGPKIGEGSFGVIFEGENI
. .  .|||| ||........
WMIVKMIGEGGFGQVYHVWDM
Kinase YCK3.AA Worm6 14-30 47 0.000353 11.28 In-house 1-17 (279) Show / Hide 
Range on Protein: 14-30
Range on HMM: 1-17/279
Sequence Identity: 47% (8 aa)

YAVGPKIGEGSFGVIFE
. |. |||||.|| ...
WKVTKKIGEGGFGAVYK
Kinase YCK3.AA Dual 102-156 28 0.000832 8.53 In-house 89-144 (282) Show / Hide 
Range on Protein: 102-156
Range on HMM: 89-144/282
Sequence Identity: 28% (16 aa)

LIIDLLGPSLEDLFE-WCGRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNF
... . ||||..         .|. .   || ||.. ..  |    . |.||| ||
WVMSPYGPSLQEIRRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANF
Kinase YCK3.AA Dual 285-315 29 0.043253 2.67 In-house 252-282 (282) Show / Hide 
Range on Protein: 285-315
Range on HMM: 252-282/282
Sequence Identity: 29% (9 aa)

AIPYQFATYLKYARSLKFDEDPDYDYLISLM
.|| ...  . |  .. .|  |||||..  .
HIPRRLKPLVSYVNGYQYDSTPDYDYFRNCL