Gene YKL161C (Bakers Yeast)

YKL161C

Species: Bakers Yeast
Alias: YKL161C
External Links: Saccharomyces Genome Database Link
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK1

Sequence

Name Sequence Type Origin Length Description Download
YKL161C.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 296 Kinase domain by global Sugen HMM Fasta, JSON
YKL161C.AA Protein Refseq_NP 433 Hypothetical ORF; Ykl161cp [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of YKL161C.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase YKL161C.AA ERK 23-318 54 3.7e-207 694.5 In-house 1-307 (307) Show / Hide 
Range on Protein: 23-318
Range on HMM: 1-307/307
Sequence Identity: 54% (167 aa)

FHLTGKIGRGSHSLICSSTYTE---SNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQII
.... .||.|.. ..||....|   ......|||.||.||| ... |||||||.|||||..||.||..|||......|.  .|..|..|||||.|| |||
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPE-QYNDIYCVEELMETDLHQII

RSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSC----SYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVD
.|.|.|.|.|.|.|.|||||.|||||||||.|.||||.|.||||.|.||||.|||..    ||.|||..|..|...|....||.||||.|..|..|||.|
NSQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMD

IWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTP-PEETLQEIASQKVYNYIFQFGN--IPGRSFESILPGAN--PEALELLKKMLEFDPKKRITVE
|||.|||.||.|||||.|.|||||...|.|.||.||| .||.||.|.|.....||....|  .|....|.| | ||  |.|..||.|||.|||.||||||
IWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRITVE

DALEHPYL
..|||||.
ECLEHPYF
Kinase YKL161C.AA MAPK 23-318 45 1.3e-169 569.74 In-house 1-328 (328) Show / Hide 
Range on Protein: 23-318
Range on HMM: 1-328/328
Sequence Identity: 45% (150 aa)

FHLTGKIGRGSHSLICSSTYTE----SNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVF-----YPNGALNGVYLYEELMEC
. .  .|| |.  . || . ..    ......||| ||...| |...||||.||.|||||...|.||..|.|    .     .... .| .|...||||.
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLSQIIRSEQRLEDAHFQSFIYQILCA--LKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSC----SYSENHKVNDG------FIKGYITSIWYKAP
|| |||.|.| |.| |.|.|.||||..  |||||||||.|.|||| |.|||..|.|||| |||..    .|...|. .|.      .  .|..  || ||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

EILLN--YQECTKAVDIWSTGCILAELLG-RKPMFEGKDYVDHLNHILQILGTPPEETLQEIA-SQKVYNYIFQF---GNIPGRSFESILPG----ANPE
||.||  ....|||||.|| |||.||.|. |||.| ||||.| .|.|...||||.|| .| |  |....||| ..    . |....|...|.    |||.
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQ

ALELLKKMLEFDPKKRITVEDALEHPYL
|. ||.|||.|||.||||||.||.|||.
AIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase YKL161C.AA CMGC 23-318 24 1.7e-123 408.02 In-house 1-513 (513) Show / Hide 
Range on Protein: 23-318
Range on HMM: 1-513/513
Sequence Identity: 24% (126 aa)

FHLTGKIGRGSHSLICSSTYTESNEE------------THVAIRKIPNAFGNKLSCK----------RTLRELKLLRHLR----------------GHPN
..  .|||.|. .  .. . ...|..             .||| || |.| ..  .|          |.|||.|.|.||.                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVWLFDTDIVFYPNGA-----------LNGVYLYEELMECDLSQIIRSEQ---------RLEDAH------------FQSFI------YQILCALK--YI
|| |.|      ..|            .| .||  |.|..|| |.|.. |          |.. |             ..|.      ||||..||  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSAN--VLHCDLKPKNLLVNSDCQL--------------------KICNFGLSCSYSENHKVNDG-----------------FIKGYITSIWYKAPEILL
||..  ..|.|||| |.|.|..|.|                    ||| |||...|.........                 ..  |. . ||.||||||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

NY---------QECTKAVDIWSTGCILAELLGR--------KPMFE-----------GKDYVDHLNHILQILGTPP---------------EETLQE---
..         .. |...|.|| |||.||.. .        ||.|            ||...|.|..| ..||||.               ||.  .   
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

------------------IASQKVYNYIFQ---FGNIPGRSFESILPG-----------------------------------ANPEALELLKKMLEFDP
                  . | ...|||..   |...|....... |.                                   ..|.|..||||||..||
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

KKRITVEDALEHPYL
.||||.|.||.|||.
DKRITAEQALQHPYF
Kinase YKL161C.AA p38 23-318 42 4.2e-104 352.16 In-house 1-289 (289) Show / Hide 
Range on Protein: 23-318
Range on HMM: 1-289/289
Sequence Identity: 42% (128 aa)

FHLTGKIGRGSHSLICSSTYTESNEE-THVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYP----NGALNGVYLYEELMECDLSQ
.     .| |.   .|.  ......   .||| |.   |   .  ||| |||.||.|.| | |.. | |   || |       .. ||.  ..|. ||..
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMR-HENVICLLD---VFTPPAHSMNDFQDVYMVTHFMGADLNN

IIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIW
|... ||| | | |  .|||| .|||||||.. | |||| |. || || |.|  |||.          |  . ||.   ||.||||.||  . |..||||
IMKC-QRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR-------HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIW

STGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPY
| |||.|||. ... | |.|..| |. |....|||.|| .| |.|..  |||     .| | |.....|||| |..|| |||| || ||||.|.|..|||
SVGCIMAELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAMQHPY

L
.
F
Kinase YKL161C.AA ERK5 23-318 42 1.8e-100 340.06 In-house 1-295 (295) Show / Hide 
Range on Protein: 23-318
Range on HMM: 1-295/295
Sequence Identity: 42% (127 aa)

FHLTGKIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQIIRSE
..   ||| |    .||       ..  |||.||||||      |||.||||.||| | | ||. . |      | . .  ||   .||| || ||| |.
YKIIEKIGNGAYGVVCSARRRKNGQQ--VAIKKIPNAFDVVTNAKRTFRELKILRHFR-HDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSN

QRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSE-NHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGC
| .   |   |.||||  |||.|||.|.| |||| |||||  | |||  ||.    .         |.  |.   ||.|||...  .. |.|.|.|| ||
QPFTLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGC

ILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQ-FGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYL
|. |...|. || || |.. |. |...||.||   .| .....||||. . | |   . .| . |.| . ||.|| .|| |.| .||||  || ||.|
IFGEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYPKADRQALDLLARMLRFEPSERITVNKALQHPFL
Kinase YKL161C.AA ERK1 23-318 45 7.9e-92 311.38 In-house 1-289 (289) Show / Hide 
Range on Protein: 23-318
Range on HMM: 1-289/289
Sequence Identity: 45% (135 aa)

FHLTGKIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQIIRSE
.     || | ....||   |   ....|||.||   |  .  |.|||||.|.|   . | ||. . |  |      ..  ||.  .||| || ..... 
YTNLQYIGEGAYGMVCSAYDTV--HKQRVAIKKI-SPFEHQTYCQRTLREIKILTRFK-HENIINIQDI-IRADTIEQMRDVYIVQCLMETDLYKLLKT-

QRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCI
|.|   |   |.||||  ||||||||||| |||| |||.|  | |||| |||      .|    ||.  |.   ||.||||.|| .  ||..|||| |||
QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPEHDHT-GFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCI

LAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYL
|||.|  .|.| || |.| ||||| .|| | .. |. |  .|  ||.      |  ..... |.| . ||.|| ||| | |.||||||.|| ||||
LAEMLSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPYL
Kinase YKL161C.AA ERK7 23-318 36 4.9e-91 308.74 In-house 1-292 (292) Show / Hide 
Range on Protein: 23-318
Range on HMM: 1-292/292
Sequence Identity: 36% (110 aa)

FHLTGKIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQIIRSE
. .  ..|.|   ..   .   . .   ||..||  || |.    || ||  .|. ...||||. | .   |.  .  .  .||  | || ||  .||  
YEIRKRLGKGAYGIVWKAYDKRTKQ--VVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLIN---VIRADNDRD-IYLVFEFMETDLHAVIRKG

QRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENH--KVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTG
. |.| | |. .||.| |.||.||.||.| |||| |.|..|.| .|.| |||  | ..    . ... .  |.   || ||||||  .. ||.|| || |
NILKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIG

CILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYL
|||.|.|  |||| |   .. .. ||.... | .| .. | |.   | . | .  . .... ..|.. ..|..|||..| | ||||.|.|.||.||| 
CILGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase YKL161C.AA nmo 23-318 40 2.3e-80 246.75 In-house 1-292 (292) Show / Hide 
Range on Protein: 23-318
Range on HMM: 1-292/292
Sequence Identity: 40% (123 aa)

FHLTGKIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNG-ALNGVYLYEELMECDLSQIIRS
 .    || |   .. |   |.  .   ||..|.|| | | .||||  ||||.|   . | |   |   ||.  |.   .. .|   |||  || .|| |
IQPDRPIGYGAFGVVWS--VTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFK-HDN--VLSALDILQPPHKDFFQEIYVVTELMQSDLHKIIVS

EQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGC
 | |   | . |.||||  |||.||||.|| |.|| ||||||.| |||| |||     .... .   .   .   .|.|||||.  .  | |||||| ||
PQHLSSDHVKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQDQSKH---MTQEVVTQYYRAPEILMGARHYTSAVDIWSVGC

ILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGN-IPGRSFESILPG---ANPEALELLKKMLEFDPKKRITVEDALEHPY
| ||||||. .|  .  .. |. | ..||||  | ..  | .   . .   .   |  .    |     |. || .||..|| ||| ||| ..|||.|||
IFAELLGRRILFQAQSPIQQLQMITDLLGTPSMEDMK-YACEGAKAHMLRMPHKPPCLQVLYTLSSPDHATHEAVHLLCRMLHFDPDKRISCKDALAHPY

L
|
L
Kinase YKL161C.AA S_TKc 23-318 25 3.1e-74 253.85 SMART 1-231 (231) Show / Hide 
Range on Protein: 23-318
Range on HMM: 1-231/231
Sequence Identity: 25% (80 aa)

FHLTGKIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMEC---DLSQII
...  |||.|. .  .  . ..     .||| .|.         ....||...|..  .||||| |.|.          . .|.  |...    || ..|
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYI

RSEQR------LEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTK-
.. .|      .   | ....|||.|||.|.|| ...|.|||| |.|...  ..||| |||.. .           . .. . || |||.|      .| 
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL----GYGKC

AVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDA
..|.|| ||||.|.| ..| |.      ... .....|                                      |||.....|.|..||.||.|. .|
KCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EA

LE-------HPYL
|.       ||..
LQDEWDIKCHPWF
Kinase YKL161C.AA Pkinase 23-318 26 7.1e-71 246.56 Pfam 1-293 (293) Show / Hide 
Range on Protein: 23-318
Range on HMM: 1-293/293
Sequence Identity: 26% (85 aa)

FHLTGKIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLR--ELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLY--EELMEC-----
.|. .|||.|| .  .  .   ...   ||. .|.    ..  ... .|  |......| .||||| |.|.           . ..|   |..|.     
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--------KDHIYMVMEYCEGGLYVM

DLSQIIR--SEQRL--EDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQL----KICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILL
||. .|.  .. ..  .. . ....||||..|.|.|| ...|.|||| |.|.......    ||| |||.. ..     |..  ...  ..|| |||...
DLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIR

NYQECTKAVDIWSTGCILAELLGRKPMFEGK----DYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEF
 .|. ...||.|| ||||.|.| ..| | |.    . .|..  | .|.|.|...  ..  |   .. ...      . ..   . ...|.....|..|..
GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--F-HWTF-HNWSEECKDFIKWCLCK

DPKKRITVEDALEHPYL
|||||.| |..|.||..
DPKKRPTAEQILQHPWF
Kinase YKL161C.AA CDK 69-318 32 1.5e-68 218.39 In-house 55-284 (284) Show / Hide 
Range on Protein: 69-318
Range on HMM: 55-284/284
Sequence Identity: 32% (87 aa)

TLRELKLLRHLRGHPNIVWLFDTDIVFYPNGAL-------NGVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLV
..|| .||..|  ||||| |.  |..   | .        | .|.  | |. ||.....          .....|.| .| |.|| ...| |||| |.|.
AIREISLLKEL--HPNIVKLH--DVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILI

NSDCQ-----LKICNFGLSCSYSENHKVNDGFIKGY---ITSIWYKAPEILLNYQECT--KAVDIWSTGCILAELLG---RKPMFEGKDYVDHLNHILQI
|.. .     |||  |||.. .. .|.   . .. |   .   || |||.||  .. .   ..|.|| |||.||..    |||.| |.   | | .| .|
NNNGEVKCGRLKIADFGLARAFGIPHQMS-EPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRI

LGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYL
.||| |..  .. .   |                          .|| ||| .||||||. |.||.|||.
CGTPTEDNWPGVTKLPDY--------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase YKL161C.AA MAPK-Unclassified 23-175 40 1.9e-50 173.92 In-house 1-156 (575) Show / Hide 
Range on Protein: 23-175
Range on HMM: 1-156/575
Sequence Identity: 40% (66 aa)

FHLTGKIGRGSHSLICSSTYTES-NEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALN----GVYLYEELMEC---D
  ... || |. .  |  . . . |    ||| |.. .| |.  |||.|||. .||.|  ||||. . |   .||. ...|     .|.  ..|.    |
YEYQKNIGSGAYGQVCRAMDKKNQNQQ--VAIKKVNHIFHNHTDCKRVLREIRILRYLN-HPNIIQIQD---IFYNKELHNQEFDDIYIVMDYMQTSLFD

LSQIIRSEQ-RLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLS
| |||.| |  ... |.| |.||||  |||.|||...| |||| |||.| || ..|| ||.|
LHQIIKSNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMS
Kinase YKL161C.AA MAPK-Unclassified 191-318 31 1.5e-42 147.68 In-house 407-575 (575) Show / Hide 
Range on Protein: 191-318
Range on HMM: 407-575/575
Sequence Identity: 31% (53 aa)

GYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGR-----------KPMFEGKD--------------------YVDHLNHILQILGTPPEETLQE
.|.   || ||||.|  .| ...||||| |||.||.. .           .|.| |.|                    ..| .. |.  ||.|||| ...
QYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPPEEDCNF

IASQKVYNYIFQFGNIPGRSFESILPGANP----------EALELLKKMLEFDPKKRITVEDALEHPYL
| . ..  ||  |.  .   | .. . ..|          |.. ...||| |.|.|||| ..|||||| 
ITCDSARKYIQSFKCKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase YKL161C.AA TyrKc 23-318 21 1.2e-11 -34.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 23-318
Range on HMM: 1-280/280
Sequence Identity: 21% (70 aa)

FHLTGKIGRGSHSLICSSTYTESNEETHVAIRKIP-NAFGNKLSCKRTLRELKLLRHL-RGHPNIVWLFDTDIVFYPNGAL---NGVYLYEELMEC-DLS
 .|  |.|.|    ..  |..     . ||. ..  .|       .  .||......|   ||||| |.   .    |        ...  |.|.  || 
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLK

QIIRSEQR-LEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSEN--------HKVNDGFIKGY--ITSIWYKAPEILL
. .|. .. |  ... || .|| |   |.|| |. | ||   | ||... . ||. ||||    .          ..  .   |   .   |. ||| . 
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-

NYQECTKAVDIWSTGCILAEL--LGRKPMFEG----KDYVDHLNHILQILGTPPEET-LQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKM
|| ..| . |.|| |  . |.  .| .|  .     ..  . .... |    |. .  . ...                  |    ... .|  .. |. 
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMS------------------F----VCCPDEMYQIMKQC

LEFDPKKRITVEDALEHPYL
 ..||..| | ..   | ..
WHEDPEDRPTFSEI--HECF