Gene YMR291W (Bakers Yeast)

YMR291W

Species: Bakers Yeast
Alias: YMR291W
External Links: Saccharomyces Genome Database Link
Annotation:

Classification

Group: CAMK
Family: CAMK-Unique

Sequence

Name Sequence Type Origin Length Description Download
YMR291W.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 313 Kinase domain by global Sugen HMM Fasta, JSON
YMR291W.AA Protein Refseq_NP 586 Hypothetical ORF; Ymr291wp [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of YMR291W.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase YMR291W.AA CAMK-Unique 39-351 35 9.5e-175 581.51 In-house 1-363 (363) Show / Hide 
Range on Protein: 39-351
Range on HMM: 1-363/363
Sequence Identity: 35% (131 aa)

VTNHNSLGDGNFSVVKECMNIHTKDLYAMKLIKKQTVKNKIQLIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFDY----FETAD-------
...|...|.|||..|.|||...|....|.|..||||..||.|..||.|||...|.||.|||..|.||.......|..|..|.|.    |....       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------NIVLITQLCQKGDLYEKIVEN-------------------QCLDLE--TQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKN
        ........||.|||...|...                   |. . |  ........||.|.....|||.|||||||.||.... ....|.  
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNN--

LQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKVNS-LKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPV----DIWALGVLTYFMAFGYTPFD
    ||.||.||.......|.||||...||..|... .....||..|.|||||.||...|||.|.|.. ..|....    |||.|||..|.|..|..|||
----HHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFD

CTTDD--------ETLECISKCDY-YVDEQMMHDP--KYEQFWNFVQCCFTIDPAVRRSAKNLKQHPFI
|...|        |..|||.|.|| ..|..|.|.|  .......||.||.|.||..|.|||.|..|..|
CECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase YMR291W.AA CAMK 44-351 19 1.4e-86 278.92 In-house 1-425 (425) Show / Hide 
Range on Protein: 44-351
Range on HMM: 1-425/425
Sequence Identity: 19% (86 aa)

SLGDGNFSVVKECMNIHTK------------DLYAMKLIKKQTVKN---------------------------KIQLIQREFDLLRSISEKIRDMEKKNE
 || |.|..||.|....|.              .|.| |.|. .|.                           . . ..|| ......... .       
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGN-------

HSLDIFEGHHHILQLFDYFE------------TADN--------IVLIT---QLCQKG----DLYEKIVENQCLD-------------L-ETQVTSYCAC
     .  | .|..|....|            | ..        .....    .|. |    ||...|||. |               . | ..  |   
-----KLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQ

LVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKVNS----------------------LKEFVGT
..| ....||..||||||| ||.|.  . ..... .  | |..  .|.  ... ..|||.|.... .. |                       .|.|.||
ICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDP-V--E-HDE-IFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGT

ISYIA-PEIVKCKGVGEMTPDQVGKL----DKYGCPVDIWALGVLTYFMAFGYTPFDCT-------------TDDETLECISKCDYYVDEQMM-------
 .|.| ||... || ..|.  . .      . || ..|.|..||..|.|  || ||.               .| |..| | |..|. .. ..       
PEYMAAPEVLNGKGHCNMQ--N-A-TDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNY

-------------HDPKYEQFWNFVQCCFTIDPAVRRSAKNLKQHPFI
             |    ..  ...... . ||  | ...  ..||..
GPEWWDDISDEFHH-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase YMR291W.AA S_TKc 39-351 22 1.9e-70 241.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 39-351
Range on HMM: 1-231/231
Sequence Identity: 22% (74 aa)

VTNHNSLGDGNFSVVKECMNIHTKDLYAMKLIKKQTVKNKIQLIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETADNIVLITQLCQK
 . .. .| | |..|. | ...|. ..|.| ||        . |.|| ..|..                    .| .| .|.|.|.. |.. ... .|  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--------------------HHPNIVKLYDVFQD-DHLYMVMEYCDG

--GDLYEKIVENQCL-----DLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSK
  |||.. |.....        | .. .|.. ... ||..||.||.||||| ||.|.                           . ..|||||...    
DLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------------------------HIKICDFGLARQL----

VNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGC-PVDIWALGVLTYFMAFGYTPFDCTTDDETLECISKCDYYVDEQMMHDPKYEQFWNFVQC
    . |.||  |.|||..                 .||. ..|.|..|.. | |. ||.||.  ....... |                 .....|.. 
----TTFCGTPWYMAPEVL-----------------GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG---------------SPEAKDFIRK

CFTIDPAVRRSAKNLKQ-------HPFI
|.. ||. | .|  . |       ||..
CLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase YMR291W.AA Pkinase 39-351 23 1e-55 196.18 Pfam 1-293 (293) Show / Hide 
Range on Protein: 39-351
Range on HMM: 1-293/293
Sequence Identity: 23% (81 aa)

VTNHNSLGDGNFSVVKECMNIHTKDLYAMKLIKKQTVKNKI-QLIQR--EFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETADNIVLITQL
 . .  .| |.|..|..|... | ...|.| |||.. | .  |   |  |  ......                   | .|..|.|.||. |.| ... .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-------------------HPNIVRLYDWFEDKDHIYMVMEY

CQKG----DLYEKIV--ENQCL--DLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEY
|..|    ||.. |   .. |.  . | .. .|.  ... ||..||.||.||||| ||.|.  . ....                  .. ..|||||. .
CEGGLYVMDLFDYISTWRHGCFYFS-EWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDA-----------------CVKICDFGLAKQF

-NTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTPFDCT------TDDETLECISKCDYYVDEQMMHDPK
 . ...  .. |.||. |.|||...             .  .|| .||.|..|.. | |..|..||.        .... .. | ....  |..  ... 
DY-NNS--MTTFCGTPWYMAPEVIR-------------GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSIS

Y----------------EQFWNFVQCCFTIDPAVRRSAKNLKQHPFI
|                | .  |. .|.. ||. | .|. ..|||..
YFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase YMR291W.AA Ciliate-E2 39-351 20 2.2e-54 185.07 In-house 1-365 (365) Show / Hide 
Range on Protein: 39-351
Range on HMM: 1-365/365
Sequence Identity: 20% (84 aa)

VTNHNSLGDGNFSVVKECMNIHTKDLYAMKLIKKQT---------VKNKIQLIQRE-FDLLRSISEKIRDMEKKNEHS---LDI------FEGHHHILQL
   .. .| |||..|..| .. .. ..|.|.|. |          ||.||  . .   . ...|. .|. | ..|.     . .      .  | .|...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FYKKI-NEKNILEQLNHPNIIKM

FDYFE--TADNIVLITQLCQKGDLYE-----------------KIVENQCLDLETQVTS--------YCACLVSVLEFLHSQG-IVHRDLKAENVLFRLR
...|.  . .|| |.. .|| |||..                 ...|...... .|...        |.||... ||.|||.. |.|||.| ||.||   
YECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---

VNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKVNSL------------------------------KEFVGTISYIAPEIVKCKGVGEMTPD
                        . ..||||. .|...  | .                              . ..||  | ||||.. |. .     
------------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ---

QVGKLDK-YGCPVDIWALGVLTYFMAFGYTPFDCTTDDETLECISKCDYYVDEQMMHDPKYE---QFW-----------NFVQC----CFTIDPAVRRS-
   .. | |.  .|||.|||. |.| ||..||        .. | .|..  ... . .. .    . |           .. .     ..  ||  | . 
---QKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKD-TQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITG

AKNLKQHPFI
.. ...||..
WEQILNHPWF
Kinase YMR291W.AA AGC 39-351 17 1.7e-53 135.6 In-house 1-395 (395) Show / Hide 
Range on Protein: 39-351
Range on HMM: 1-395/395
Sequence Identity: 17% (81 aa)

VTNHNSLGDGNFSVVKECMNIH------TKDLYAMKLIKKQTVKNKIQLIQREFDLLRSISEKIRDMEKKNEHS------------LDIFE--G------
   .  .| | |. |  .   .      |...|||| .||..                 | .| ..|....                .|.|         
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKH----------------KIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHP

----HHHILQ-LFDYFETADN--IVLITQLCQ---------KG-DLYEKIV---ENQCLDLETQVTSYCAC-------LVSVLEFLHS-QGIVHRD-LKA
    |  | . |.  |.. |.  . .. ....          | .|.  .     ....| | ..  |.|.       .|. ||.||| .||.||| || 
IKSHHPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFD-EERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKP

ENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTS-------------------------------------------------KVNS
||.|.  .                        . |.||||. | ...                                                 | . 
ENILLDED----------------------GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDR

LKEFVG--TISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWA--LGVLTYFMAFGYTPFDCTTDD----------ETLECISKCDY--YVDEQMMHD
 . |.|  |  |.||||.                  || ..|.|.  ||.| | | .||.||   ...          |. . | ...|    .... ..
TWTFCGPCTPEYMAPEIL------------------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFP

--------PKY-EQFWNFVQCCFTIDPAVRRS----------AKNLKQHPFI
        ..  .. ..... ... ||. |            |. .|.||. 
EDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase YMR291W.AA Ciliate-E2-Unclassified 38-351 20 8e-49 167.47 In-house 1-352 (352) Show / Hide 
Range on Protein: 38-351
Range on HMM: 1-352/352
Sequence Identity: 20% (77 aa)

YVTNHNSLGDGNFSVVKECMNIHTKDLYAMKLIKKQTVKNKIQLIQREFDLLRS--ISEKIR--DMEKKNEHSLD---IFEGHHHILQLFDYFETADNIV
|  ..  .| |.|..|..| .. .| .|||| .||. .... |  . . .....  . ...   ... |..  ..   .   | .|. .|..|.. .|| 
YKIIKQ-IGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQR-KYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY

LITQLCQKGDLYEKIV----------------ENQCLDLETQVT-----SYCACLVSVLEFLHSQG-IVHRDLKAENVLFRLRVNENEKNLQGEHHGDFK
.....|. ||| . |                 ....   | |.       |.|.... ||.||... |.|||.| ||.||    .               
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK---------------

YDLLAHDLVLADFGLAAEYNTS--------------KVNSLKEFVGTISYI----APEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYT
       . ..|||.. .|...              | . .. |.||..|.    |||. . .. ....             .|||.|||. |.| ||| 
----NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA----------YKCDIWSLGVILYEMLFGYY

PFDCTTDDE----------------TLECISKCDYYVDEQMM------HDPKYEQFWN-FVQCCFTIDPAVRRSAKNLKQHPFI
||.......                 .. | .........         .|... | | . |...  .|  | ... ...||..
PFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase YMR291W.AA CAMKL 112-351 24 4e-41 128.9 In-house 72-297 (297) Show / Hide 
Range on Protein: 112-351
Range on HMM: 72-297/297
Sequence Identity: 24% (66 aa)

G-HHHILQLFDYFETADN------IVLITQLCQKGD--LYEKIVENQC----LDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKN
| | .| .|.. .|| ..      |.|.. .|. |.  |...||.. .    .. | .   |   .|| ....||.||||||.|.||.|.  . |.    
GKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMP-EHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN----

LQGEHHGDFKYDLLAHDLVLADFGLAAEYN---TSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVG-KLDKYGCPVDIWALGVLTYFMAFGYTPFDC
                 . ..|||....|      . . ||.| |. .| ||||..            | . . .| .||||..||. |.| .|| |||.
----------------NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQ------------GNNKPYDGPKVDIWSCGVILYAMVCGYLPFDD

TT-------DDETLECISKCDYYVDEQMMHDPKYE-QFWNFVQCCFTIDPAVRRSAKNLKQHPFI
 |       .  .|. . .|. |    ..  ...  .  .. .   . .|  | .......||. 
DTYNKQGKDNI-YLYWKIMCG-Y----YPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase YMR291W.AA STE 40-288 17 3.3e-37 128.95 In-house 1-264 (359) Show / Hide 
Range on Protein: 40-288
Range on HMM: 1-264/359
Sequence Identity: 17% (55 aa)

TNH-NSLGDGNFSVVKECMNIH---------------TKDLYAMKLIKKQTVK----------------NKIQLIQREFDLLRSISEKIRDMEKKNEHSL
  .   .| |.| .|  .||..               |....|.| ..... .                ...| |..| ....  .              
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNH-------------

DIFEGHHHILQLFDYFETA-------DNIVLITQLCQKGDLYEKIVEN-QCLDL------------ETQVTSYCACLVSV-LEFLHSQGIVHRDLKAENV
     | .| . .....         |.. ..  ..  | | . | ..  |..             |.|.  .|  ..   |..|||..|.|||.|. |.
---M-HPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANI

LFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNT---------------SKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGC
|.                             |.|||...  .                . .   . ||||  . |||.... | |          ..|..
LL---------------------------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-R-------DKGYDT

PVDIWALGVLTYFMAFG
 .||| || .   || |
KCDIWSLGCTIIEMATG
Kinase YMR291W.AA RSK 42-188 33 3.8e-25 86.8 In-house 4-134 (271) Show / Hide 
Range on Protein: 42-188
Range on HMM: 4-134/271
Sequence Identity: 33% (50 aa)

HNSLGDGNFS---VVKECMNIHTKDLYAMKLIKKQTVKNKIQLIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHH-HILQLFDYFETADNIVLITQLCQ
|  .| | ||   |.| |    |...|||| ||| |...| .            .| .|..           .|||  | .|.. |... .. .|. ...
HECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR----------VCWEEERII---------LRYGHHPFIVKLHYVFQDEGKVYMIMDFMR

KGDLYEKIVENQCLDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLF
 |||  ...   ..  |  |  | | . . .|.||||||||||||.||.|.
GGDLFDRLLKQKMF-SEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILY
Kinase YMR291W.AA CAMK1 40-148 22 3.6e-21 58.24 In-house 2-102 (276) Show / Hide 
Range on Protein: 40-148
Range on HMM: 2-102/276
Sequence Identity: 22% (26 aa)

TNHNSLGDGNFSVVKECMNIHT---KDLYAMKLIK-KQTVKNKIQ----LIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETADNIVL
 ... .| | ||.|..| .. |   .. ||.| |. |. .|.| .    ....| . ... |                   | .| ......|. . . |
EFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVS----------------KIDHPNIIKFYEWYESDNHFYL

ITQLCQKGDLYEKIVEN
...|.. |.| ..|||.
VMELVTGGELFDRIVEK
Kinase YMR291W.AA CAMK1 214-351 29 2e-20 56.06 In-house 148-276 (276) Show / Hide 
Range on Protein: 214-351
Range on HMM: 148-276/276
Sequence Identity: 29% (42 aa)

HDLV--LADFGLAAEYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTPFDCTT-DDETLECISKCDYY
....  .|||||.  .. ...| .|  .||..|.|||...||             . |. ..|.|  || ||.. .|| ||   . |.| .|.|.||.| 
SKIKRSIADFGLSKIFD-HDENLMKTACGTPGYVAPEVLECKK-----------DKPYDKACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYE

VDEQMMHDPKYEQ-FWNFVQCCFTIDPAVRRSAKNLKQHPFI
 ..    |   .|   .|. .  . ||  | ...   .||.|
FPSPW-WDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase YMR291W.AA RSK 216-351 25 3.1e-17 59.83 In-house 146-278 (278) Show / Hide 
Range on Protein: 216-351
Range on HMM: 146-278/278
Sequence Identity: 25% (37 aa)

LVLADFGLAAEYNTSKVNSLKEFVGTISYIAPEIVKC--KGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTPFDC---TTDDETLECISKCDYY
..| |||.. . . .. . .. |..|| |.|||..|   ...|            ..  .|.| |||| | | .|..||      . .|... | |... 
IKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGG------------HDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKF-

VDEQMMHDPKY--EQFWNFVQCCFTIDPAVRRS-----AKNLKQHPFI
   ..|  ..|  . . .... ... ||. | .     |. .||||..
--SLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase YMR291W.AA RSK 112-188 35 1.1e-15 54.15 In-house 59-137 (278) Show / Hide 
Range on Protein: 112-188
Range on HMM: 59-137/278
Sequence Identity: 35% (28 aa)

GHHHILQLFDYFETADNIVLITQLCQKGDLYEKIVENQCLD--LETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLF
.|  | .|.. |.| . . ||...|  |.|.... . ...    |. .  | | .|. .|.||.|||.||||| ||.|.
QHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILY
Kinase YMR291W.AA CAMK1 164-189 57 2.5e-11 29.1 In-house 117-142 (276) Show / Hide 
Range on Protein: 164-189
Range on HMM: 117-142/276
Sequence Identity: 57% (15 aa)

LVSVLEFLHSQGIVHRDLKAENVLFR
..| .|..||.|||||||| || |..
ILSAVEYMHSKGIVHRDLKPENLLYY
Kinase YMR291W.AA TyrKc 39-351 16 1.1e-10 -49.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 39-351
Range on HMM: 1-280/280
Sequence Identity: 16% (59 aa)

VTNHNSLGDGNFSVVKECMNIHTKDLYAMKLIKKQTVKNKIQLIQREFDLLRSI--SEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETA-------DNI
.|    || |.| .| ... .      | | .|. .    .. . ||  .....  .                   | .|..|. .  .        . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGH-------------------HPNIVRLYGVCTQQGRNFMYIEPL

VLITQLCQKGDLYEKIVENQCLDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLV-LADFGLAAEYN
 ... .. .||| . . ...      .  |.|    .  |.|||....|||| | |.|    |.||                     |  .||||. .  
MIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCL----VGENH-------------------TVKISDFGLSRDIY

TS-------KVNS-----LKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTY-FMAFGYTPFDC-----TTDDETLECISKCDYY
         .. .      . ..  |   |||                .  |.    |.|. ||. .  . .| .|         ...| .|.. .   |
DDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--------------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQG--Y

VDEQMMH--------DPKYEQFWNFVQCCFTIDPAVRRSAKNLKQHPFI
  .|. .         |.     .  ..|   ||. | . ...  | ..
RMPQPPNDYPMSFVCCPDE--MYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase YMR291W.AA CAMKL 45-93 21 4.9e-09 24.83 In-house 7-70 (297) Show / Hide 
Range on Protein: 45-93
Range on HMM: 7-70/297
Sequence Identity: 21% (14 aa)

LGDGNFSVVKECMN-IHTKDLYAMKLIKKQTVK-NKIQL-------------IQREFDLLRSIS
|| |.|..|| ... ..|.  .|.| |.|.  . . . .             |.||  ......
LGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN
Kinase YMR291W.AA RSK 218-306 29 5.8e-09 28.35 In-house 146-219 (271) Show / Hide 
Range on Protein: 218-306
Range on HMM: 146-219/271
Sequence Identity: 29% (26 aa)

LADFGLAAEYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTPFDCTTDDETLECISK
..|||.| .   ..   |. | .|. |.|||..| .|              ..  .|.| .||| | |  |.|||  ...|.. . | .
ICDFGFAKQ-LRDENGMLMTFCYTANYMAPEVLKRQG--------------HDQACDWWSFGVLMYEMLTGCTPFQNKPRDTPMNIIQR
Kinase YMR291W.AA STE 326-351 39 3.7e-08 25.04 In-house 332-359 (359) Show / Hide 
Range on Protein: 326-351
Range on HMM: 332-359/359
Sequence Identity: 39% (11 aa)

NFVQCCFTIDPAVRRSAKNLKQ--HPFI
.|.. |...||  | .|. | .  ||||
DFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase YMR291W.AA RSK 42-78 27 2e-06 19.73 In-house 1-40 (278) Show / Hide 
Range on Protein: 42-78
Range on HMM: 1-40/278
Sequence Identity: 27% (11 aa)

HNSL---GDGNFSVVKECMNIHTKDLYAMKLIKKQTVKNK
.  |   | | ......| .  |. .|||| .|| .....
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQR
Kinase YMR291W.AA RSK 332-351 32 0.001104 9.3 In-house 247-271 (271) Show / Hide 
Range on Protein: 332-351
Range on HMM: 247-271/271
Sequence Identity: 32% (8 aa)

FTIDPAVRRSA-----KNLKQHPFI
...||. | .|     .  ||||..
LHRDPHNRLGAGPNGVEQIKQHPWF