Gene BMPR2 (Human)

BMPR2

Species: Human
Alias: T-ALK, BMPR-II, PPH1, BRK-3, BMR2, BMPRII, BMPR2, BMPR3
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 2q33-q34 ,

Classification

Group: TKL
Family: STKR
Subfamily: STKR2

Sequence

Name Sequence Type Origin Length Description Download
BMPR2.AA Protein Sugen Kinome 1038 None Fasta, JSON
BMPR2.kin_dom Protein Kinase Domain Sugen Kinome 299 None Fasta, JSON
BMPR2.NA RNA Sugen Kinome 12086 None Fasta, JSON

Protein domain

Protein domains of BMPR2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Activin_recp BMPR2.AA Activin_recp 32-131 23 5.7e-33 111.19 Pfam 1-121 (121) Show / Hide 
Range on Protein: 32-131
Range on HMM: 1-121/121
Sequence Identity: 23% (29 aa)

RLCAFKDPYQQDLG--IGESRISHENGTILCSK----------GSTCYGLWEKSKGD--INLVKQ----GCWSHIGDPQECHYEECVV--TTTPPSIQNG
..| | ..|.....   .|.. ..|...  |..          . .|| .||.....  ......    ||||.......||...|..  .|..|....|
LKCYFCNGYWEYDYQICHENENNFEIPVHTCETHPDKMCFYCYDGQCYVSWEYNDDEEDTEQHQRMHMYGCWSLNENCPQCHPFMCKSYKHTHSPPHRHG

TYRFC-CCSTDLCNVNFTENF
.. .| ||.||.||.|.| ..
HNHECWCCETDYCNRNLTPPP
Kinase BMPR2.AA Type2 203-501 52 1.4e-221 738.66 In-house 1-315 (315) Show / Hide 
Range on Protein: 203-501
Range on HMM: 1-315/315
Sequence Identity: 52% (166 aa)

LKLLELIGRGRYGAVYKGSLDER-----PVAVKVFSFANRQNFINEKNIYRVP-LMEHDNIARFIVGDER--VTADGRMEYLLVMEYYPNGSLCKYLSLH
..|.||||.||.|.|.|......     .||||.|.....|...|||.||..| .|.|.||..||....|   ..||.|||.||.|....||||.||. |
IQLMELIGKGRFGCVWKAQWHNNNGEKRTVAVKIFPEQDKQSWQNEKDIYSLPYHMWHENILQFICAEKRRVHMGDGWMEYWLVTEFHHKGSLCDYLKQH

TSDWVSSCRLAHSVTRGLAYLHTELPRGDH---YKPAISHRDLNSRNVLVKNDGTCVISDFGLSMRLTGNRLVRPGE----EDNAAISEVGTIRYMAPEV
|.||...||.|.|..||||.||.|......   .||.|.|||..|.|||||||.||.|.||||.||..... ....|    .|...|..|||.|||||||
TIDWHECCRMAMSMARGLAHLHEEIWQWCQTDHHKPPIAHRDIKSKNVLVKNDMTCCIADFGLAMRFCPGKQPYKWEPTMPGDTHNIGQVGTRRYMAPEV

LEGAVNLRDCESALKQVDMYALGLIYWEIFMRCTDLFPGESVPEYQMAFQTEVGNH-PTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQ
||||||..||..|.||.||||.||..||...||||..|...||||||.|..|||.| |.|||||.||.|...||..|..||... ..|.|.||||||||.
LEGAVNFQDCRDAFKQMDMYAMGLVLWEMVSRCTDHYPDDEVPEYQMPFEEEVGQHDPSFEDMQELVVRKRKRPQWPDHWKCHPGMQRMLCETIEDCWDH

DAEARLTAQCAEERM
||||||||||..|||
DAEARLTAQCVQERM
Kinase BMPR2.AA STKR 203-501 50 3.2e-197 642.59 In-house 1-312 (312) Show / Hide 
Range on Protein: 203-501
Range on HMM: 1-312/312
Sequence Identity: 50% (156 aa)

LKLLELIGRGRYGAVYKGSLDE----RPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIVGDERVTADGRMEYLLVMEYYPNGSLCKYLSLHTSDW
..|.|.||.||||.|.||....    . ||||.|.....|.. .|..||. |.|.|.|| .||  |.. |......|.|..||..||||| ||. ||.||
IQLIECIGKGRYGEVWKGKWRGNGEKETVAVKIFPSRDEQSWFRETEIYQTPMMRHENILQFIAADMKHTEGSWTQYWLITEYHENGSLCDYLKRHTIDW

VSSCRLAHSVTRGLAYLHTELP--RGDH-YKPAISHRDLNSRNVLVKNDGTCVISDFGLSMRLTGNRLVRPGE---EDNAAISEVGTIRYMAPEVLEGAV
 ..||.|||...|||.||.|..  .... .||||.|||..|.|.||||||||.| ||||.||..... . ...   .|||.. .||| ||||||||.||.
HEMCRMAHSMACGLAHLHMEIWGWGTQQHHKPAIAHRDIKSKNILVKNDGTCCIADFGLAMRHDPDTNQIDIHNTMQDNAQNTQVGTKRYMAPEVLDGAM

NLRDCESALKQVDMYALGLIYWEIFMRCTDLFP---GESVPEYQMAFQTEVGNHPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAE
|....|||.|..||||.||..|||..||||. |   ...||||||.|...|.|||.||||| .|.|..|||..|..||.|. |.||...|.|.|||.|.|
NFQCFESAFKRMDMYAMGLVMWEIARRCTDGGPDLVDQIVPEYQMPFYDWVPNHPSFEDMQKVVCRKRQRPNIPNRWKCNHPAMRSMCKTMEECWDHDPE

ARLTAQCAEERM
|||||.| ...|
ARLTALCVKKTM
Kinase BMPR2.AA Type1 203-494 38 6.8e-105 284.93 In-house 1-283 (290) Show / Hide 
Range on Protein: 203-494
Range on HMM: 1-283/290
Sequence Identity: 38% (112 aa)

LKLLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIVGDERVTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSC
....| ||.|||| |..|.     ||||.|. .  . . .|  ||   .| |.|| .||  | . . .   . .|...|...|||  ||. || |  . .
IQMIECIGKGRYGEVWRGKWRGENVAVKIFFSRDERSWFRETEIYQTVMMRHENILGFIAADMKDN-GSWTQLWLITDYHEHGSLYDYLNRHTLDTQQML

RLAHSVTRGLAYLHTELPRGDH--YKPAISHRDLNSRNVLVKNDGTCVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRYMAPEVLEGAVNLRDCESA
|||.|.  |||.||.|   |     |||| |||. |.|..||..|.|.| |.||. | .        . | .    ||| ||||||||.   | .. || 
RLAYSCACGLAHLHMEI-FGTQEFGKPAIAHRDIKSKNIMVKKNGQCCIADLGLAVRHQQDT----DQIDIGQNPRVGTKRYMAPEVLDETMNMNCFES-

LKQVDMYALGLIYWEIFMRCTDLFPGESVPEYQMAFQTEVGNHPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTA
 | .|.|..||..|||  || .      | .||. .   | | |.||||.  |  .|.||..| .|.... . |..    ..|| | ..||.||
YKMADIYSFGLVMWEIARRCEVGG---IVEDYQLPYYDWVPNDPSFEDMRKVVCVRKLRPNIPNRWQSHP-CMRHMAKLMKECWYQNPHARHTA
Kinase BMPR2.AA TKL 209-501 25 3.9e-91 309.07 In-house 1-364 (364) Show / Hide 
Range on Protein: 209-501
Range on HMM: 1-364/364
Sequence Identity: 25% (98 aa)

IGRGRYGAVYKGSLDE----------RPVAVKVFSF-------------------------ANRQNFINEKNIYRVPLME---HDNIARFIVGDERVTA-
||.|..| |||| .            ..||||.|.                          .. . ..... .. . .|    |.|| .|.  . . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------DGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELP---RGDHYKPAISHRDLNSRNVLVKNDGT-------------
       .. ... .||||.|.|||. ||      |   ||.|... ||..|||.. |   .    ||.| ||||.|.|.||....|             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCT----KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-CVISDFGLSMRLTGNRLVRPGE-----------EDNAAISEVGTIRYMAPEVLEGAVNLRDC---------ESALKQVDMYALGLIYWEIFMRCTDLFP
 | |.||||| .....     ..            ... ....||.|.||||||.|. |....         ... ...|.|. |.. |||. ||.    
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR----

GESVPEYQMAFQTEVGNHPTFEDMQVLVSREKQRPKFPEAWKE------NSLAVRSLKETIEDCWDQDAEARLTAQCAEERM
    |.|.. . ......| ||.|...|. ...||  |. |..      .. . .|.|. ..||||.|.|.|...|.  .|.
----PYYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase BMPR2.AA Pkinase 203-501 21 1.6e-40 144.32 Pfam 1-293 (293) Show / Hide 
Range on Protein: 203-501
Range on HMM: 1-293/293
Sequence Identity: 21% (72 aa)

LKLLELIGRGRYGAVYKGSLDERP--VAVKVFSFANRQNFINEK-----NIYRVPLMEHDNIARFIVGDERVTADGRMEYLLVMEYYPNG----SLCKYL
..... ||.| .| |||.     .  ||||...  ..    ..       |.    . |.|| |..   |.     . .. .|||| ..|    .|. |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDYI

S---LHTS--DWVSSCRLAHSVTRGLAYLHTELPRGDHYKPAISHRDLNSRNVLVKNDGTC----VISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRY
|     .   ..   .. .  . |||.|.| .          | |||| . |.|..|.|..     |.||||.  .           .  . . .||..|
STWRHGCFYFSEWECKFYMYQILRGLEYCHSM---------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-------Y-NNS-MTTFCGTPWY

MAPEVLEGAVNLRDCESALKQVDMYALGLIYWEIFMRCTDLFPGESVPEYQMAFQTEVGNHPTFEDMQVLVSREKQRPKFPEAWKENSLAV---------
|||||      .|...   . |||...|.| .| . .                |. .. .|..  |..... | ...|   . ....|            
MAPEV------IRGGQYYGPKVDMWSCGCILYEMLCGR-------------PPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFH

-------RSLKETIEDCWDQDAEARLTAQCAEER--M
       ...|. |..|...| . |.||... .   .
WTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase BMPR2.AA MLK 203-389 25 1.1e-29 100.17 In-house 1-206 (291) Show / Hide 
Range on Protein: 203-389
Range on HMM: 1-206/291
Sequence Identity: 25% (57 aa)

LKLLELIGRGRYGAVYKGSLDERP-----VAVKVFSF-------ANRQNFINEKNIYRVPLMEHDN----IARFIVGDERVTADGRMEYLLVMEYYPNGS
....| || | .|.|.||    .      |||| . .       .  .    |. ....  . | |    | .|  .    . ..  ....|||| ..||
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGV---CLQPP-CHFCIVMEYCEGGS

LCKYLSLHTSDWV---------------SSCRLAHSVTRGLAYLHTELPRGDHYKPAISHRDLNSRNVLVKN------DGTCVISDFGLSMRLTGNRLVR
|. .|   .| |                .  . |. . ||..||| ..|      ..| ||||.|.|.|. .      .||..|.|||.|  ..      
LYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAP------KPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWH------

PGEEDNA-AISEVGTIRYMAPEVLE
  . . .   |  || ..|||||..
--QMC-TNMMSNAGTYAWMAPEVIQ
Kinase BMPR2.AA TK 203-389 16 1.5e-25 81.98 In-house 1-358 (486) Show / Hide 
Range on Protein: 203-389
Range on HMM: 1-358/486
Sequence Identity: 16% (61 aa)

LKLLELIGRGRYG---AVYKGSLDER---------------------------PVAVKVFSFANRQNFINEKN----------------IYRVPLME---
..|.. .|.| .|    |||| . .|                           |||||.    . ..   ..                   .  ...   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HDNIARFIV----GDER-----VTADGRMEYLLVMEYYPNGS----LCKYLS-----------------------------------------------
 |.|| |..     |...     |  ...  ...|||| |.|.    | .||                                                
HHPNIVRLYGVCTQGEPKPCFEVV--VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQ

-------------LHTSDWVSSCR----------------LAHSVTRGLAYLHTE---LPRGDHYKPAI---SHRDLNSRNVLVKNDGT-----------
             |.|.| .. ..                 .. . .|..|||     .         |    ||||  ||.|| ....           
DYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEF---------IQNFVHRDLAARNCLVGENNVCKWHFDGCGPV

CVISDFGLSMRLTGN---RLVRPGEEDNAAISEVGT------------------------IRYMAPEVLE
| |.|||||   .     | . ....  .. |. ..                        ||.||||.|.
CKIADFGLSRQGS-GVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLN
Kinase BMPR2.AA TKL-Unique 205-420 29 1.2e-24 83.96 In-house 1-225 (290) Show / Hide 
Range on Protein: 205-420
Range on HMM: 1-225/290
Sequence Identity: 29% (72 aa)

LLELIGRGRYGAVYKGSLDERPVAVKVFSF----ANR--QNFINEKNIYRVPLME-HDNIARFIVG--DERVTADGRMEYLLVMEYYPNGSLCKYLS---
 ...||.| ||.||||     |||.|.|..     |.  |.|.||.|.  .   . |.|| ... .  |. |..    .. .||||.| ||| ..|.   
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKK--LHYHPNIVHYMGYCMDHQVYP---PNMCIVMEYCPGGSLYDVLHQNN

--------LHTSDWVSSCRLAHSVTRGLAYLHTELPRGDHYKPAISHRDLNSRNVLVKND-----GTCVISDFGLSMRLTGN---RLVRP--GEEDNAAI
         .. ..    ..|. . .|. |||       |..| | |||| |.|.|| |.         |.|||||  .. .    . ..  .       
NNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLH-------HCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTR----NQ

SEVGTIRYMAPEVLEGAVNLRDCESALKQVDMYALGLIYWEIFMRC
...|..|.||||||..  .....     ..| |. | . |||. |.
TRCGSFRWMAPEVLRMNFCQYSE-----KSDVYSFGIVLWEIATRK
Kinase BMPR2.AA S_TKc 203-502 21 5.6e-24 86.89 SMART 1-231 (231) Show / Hide 
Range on Protein: 203-502
Range on HMM: 1-231/231
Sequence Identity: 21% (67 aa)

LKLLELIGRGRYGAVYKGSLDE--RPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIVGDERVTADGRMEYLLVMEYYPN--GSLCKYLSLHTS--
 ..|..||.| .| |||.   .  | ||.|. .    .....| .| .     |.|| ...   .        .. .|||| ..  |.| .|.  . .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK---HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRHG

-----DWVSSCRLAHSVTRGLAYLHTELPRGDHYKPAISHRDLNSRNVLVKNDGTCVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRYMAPEVLEGA
     .    ..... . ..|.|.        | .  | ||||   |.|. .  .  |.||||. .|                . .||  |||||||   
LRFPFPE-HARFYMYQICCALEYC--------HSH-GIIHRDLKPENILLDE--HIKICDFGLARQL---------------TTFCGTPWYMAPEVL---

VNLRDCESALK-QVDMYALGLIYWEIFMRCTDLFPGESVPEYQMAFQTEVGNHPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEA
       .  |  .|....| | .| . ... .||     ..|| |.  .                                 ...|. |. |.. | | 
-------GYGKCKCDWWSCGCILYEMLCGYP-PFP-----QMQMMFKKIG--------------------------------SPEAKDFIRKCLQKDPEK

RLTAQCAE-------ERMA
|.||.. .           
RPTAEALQDEWDIKCHPWF
Kinase BMPR2.AA UTK 203-388 24 2.8e-18 59.16 In-house 1-211 (296) Show / Hide 
Range on Protein: 203-388
Range on HMM: 1-211/296
Sequence Identity: 24% (57 aa)

LKLLELIGRGRYGAVYKGSLDERP-------VAVKVFS---FANRQ-----NFINEKN---IYRVPLMEHDNIARFI---VGDERVTADGRMEYLLVMEY
..|....|.|..| |.|..... .       ||||| .   .|...      |..| .   ..  .  .| |..|..   . .|          ..|.||
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFH-WHPNVLRLVGVCTQEEP--------WMIVTEY

YPNGSLCKYLSLHTS------DWVSSCR---LAHSVTRGLAYLHTELPRGDHYKPAISHRDLNSRNVLVKNDG-------TCVISDFG---LSMRLTGNR
..||.| .||  |.       .|.....    |  . ||..|||.           . ||||  ||.||  ..       .|.|.|||   .| |. . .
MENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCG---------FVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFH

LVRPGEEDNAAISE-VGT--IRYMAPEVL
     .|..   .  ..   || ||||.|
FSNRYWESYYYMAQHQDRWPIRWMAPEAL
Kinase BMPR2.AA HH498 274-417 29 2.2e-14 41.61 In-house 77-220 (284) Show / Hide 
Range on Protein: 274-417
Range on HMM: 77-220/284
Sequence Identity: 29% (48 aa)

EYLLVMEYYPNGSLCKYL--------------SLHT-----SDWVSSCRLAHSVTRGLAYLHTELPRGDHYKPAISHRDLNSRNVLVKNDGTCVISDFGL
. ..| .|  ||||   |                        |  |  ...  | .|  |||  |      |. | |||||| |.|.  ||  |. ||| 
QFAIVTQYCDNGSLFSILNTIPIGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSL------KHPIIHRDLNSHNILIHEDGHAVVADFGE

SMRLTGNRLVRPGEEDNAAISEVGTIRYMAPEVLEGAVNLRDCESALKQVDMYALGLIYWEIF
|      | |.  ..||   .  |  |.|||||         |    . || .  ... ||..
S------RFVCDMHDDNMT-KQPGNLRWMAPEVFS------QCQKYSIKVDVFSYAMCIWEMH
Kinase BMPR2.AA TyrKc 203-501 24 4.3e-14 5.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 203-501
Range on HMM: 1-280/280
Sequence Identity: 24% (80 aa)

LKLLELIGRGRYGAVYKGSLDERPVAVKVFS-FANRQNFINEKNIYRVPLM--EHDNIARFIVGDERVTADGR-----MEYLLVMEYYPNGSLCKYLSLH
..|.. .|.| .| |||| .. ..||||.    | |. |..| .| .      .|.|| |..     .| .||       ...|||| |.|.| .||  |
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMCK--LGGHHPNIVRLYGV---CTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

TS--DWVSSCRLAHSVTRGLAYLHTELPRGDHYKPAISHRDLNSRNVLVKNDGTCVISDFGLSMRLTGN-------RLVRPGE--EDNAAISEVGTIRYM
     .   .  .. . .| .|||            . ||||  ||.||....|. |||||||  ..            |. |    ..    .  || |
RPKLCMKDLLSFCWQIACGMEYLHSK---------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKT----MLPIRWM

APEVLEGAVNLRDCESALKQVDMYALGLIYWEIFMRCTDLFPGE---SVPEYQMAFQTEVGNHPTFEDM----QVLVSREKQRPKFPEAWKENSLAVRSL
|||..    | . . ..    | .. |   |||| ..    ||.    .. ...  . . |. .   .                 |         .   .
APECI----NYGKFTTK---SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-----------F-------VCCPDEM

KETIEDCWDQDAEARLTAQCAEERM
 . ...||. |.| | | .   |..
YQIMKQCWHEDPEDRPTFSEIHECF
Kinase BMPR2.AA MOS 203-281 34 1.7e-12 37.51 In-house 1-82 (299) Show / Hide 
Range on Protein: 203-281
Range on HMM: 1-82/299
Sequence Identity: 34% (29 aa)

LKLLELIGRGRYGAVYKGSLDERPVAVKVFS------FANRQNFINEKNIYRVPLMEHDNIARFIVGDERVTADGRMEYLLVMEY
 .|...|||| .| |.|.    ||||||.         | |. | .| |. |    .|||| | .    |  .|.    . .||.
VCLCQMIGRGGFGSVWKAQYCGRPVAVKQVNKCTKNLKAMRRSFWAEVNYLR---LRHDNIVRVMAVSQRSPEDFNNLGTIIMEC
Kinase BMPR2.AA Pkinase_Tyr 331-355 52 7.3e-08 27.26 Pfam 134-158 (270) Show / Hide 
Range on Protein: 331-355
Range on HMM: 134-158/270
Sequence Identity: 52% (13 aa)

HRDLNSRNVLVKNDGTCVISDFGLS
||||  ||.||...... |.||||.
HRDLAARNCLVTENNVVKICDFGLA
Kinase BMPR2.AA Pkinase_Tyr 203-231 34 1e-07 26.77 Pfam 1-35 (270) Show / Hide 
Range on Protein: 203-231
Range on HMM: 1-35/270
Sequence Identity: 34% (12 aa)

LKLLELIGRGRYGAVYKGSLD------ERPVAVKV
..... .|.| .| |||| ..      . |||||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKM
Kinase BMPR2.AA MOS 335-390 32 1.4e-05 14.26 In-house 158-212 (299) Show / Hide 
Range on Protein: 335-390
Range on HMM: 158-212/299
Sequence Identity: 32% (19 aa)

NSRNVLVKNDGTCVISDFGLSMRLT---GNRLVRPGEEDNAAISEVGTIRYMAPEVLEG
||  . ||    | ..||| | ..    |  . .. .   .     || .|||||.| |
NSSKIKVKRQDVCKLCDFGCSQQMFDSNGKEFCAWTNPHYLK----GTCTYMAPELLCG
Kinase BMPR2.AA HH498 203-230 46 8.3e-05 10.74 In-house 1-28 (284) Show / Hide 
Range on Protein: 203-230
Range on HMM: 1-28/284
Sequence Identity: 46% (13 aa)

LKLLELIGRGRYGAVYKGSLDERPVAVK
.. .| || | .| ||||      ||||
IEFHEKIGSGSFGKVYKGEWRNKIVAVK
Kinase BMPR2.AA MOS 468-506 30 0.040154 2.59 In-house 264-299 (299) Show / Hide 
Range on Protein: 468-506
Range on HMM: 264-299/299
Sequence Identity: 30% (12 aa)

ENSLAVRSLKETIEDCWDQDAEARLTAQCAEERMAELMM
|||.    ... |  || . .| |..   |..   || |
ENSCENDWYRQLIQKCWPKQPEQRPS---ARQLKHELEM
Kinase BMPR2.AA Pkinase_Tyr 274-291 50 2.266787 1.88 Pfam 81-98 (270) Show / Hide 
Range on Protein: 274-291
Range on HMM: 81-98/270
Sequence Identity: 50% (9 aa)

EYLLVMEYYPNGSLCKYL
....|||| |.|.| .||
QIYIVMEYMPHGDLLDYL